# Clinique Smart Clinical Repair Wrinkle Correcting Serum for oily acne-prone skin

**Lovi Fit: Average fit for oily acne-prone skin.**
Oily Skin Fit: High · Effectiveness: Average · Safety: High.

Page: https://lovi.care/skincare/sg/p/clinique/smart-clinical-repair-wrinkle-correcting-serum/for/oily-acne-prone-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Singapore.

Brand: [Clinique](https://lovi.care/skincare/sg/brands/clinique)
Category: [Serums and treatments](https://lovi.care/skincare/sg/best/serums)

This fit is calculated for the concerns frequently associated with oily acne-prone skin: shine, breakouts, blemishes, and enlarged pores. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for oily acne-prone skin; other serums fit it better.

## Why this fit

- Highly suitable for oily skin due to ingredients like dimethicone and polysilicone-11, which provide emollient and occlusive benefits without feeling heavy, while peptides such as acetyl hexapeptide-8 and palmitoyl tripeptide-1 offer moderate wrinkle reduction by smoothing texture.
- The serum also provides general skincare benefits like hydration and soothing, supported by glycerin and sodium hyaluronate, which are beneficial for oily and acne-prone skin.
- The safety profile is excellent, with no risks of irritation for your oily skin due to the absence of harsh ingredients and the presence of soothing components like glycerin and squalane.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/sg/p/clinique/smart-clinical-repair-wrinkle-correcting-serum/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/sg/p/clinique/smart-clinical-repair-wrinkle-correcting-serum/for/dry-skin): Average
- [Combination skin](https://lovi.care/skincare/sg/p/clinique/smart-clinical-repair-wrinkle-correcting-serum/for/combination-skin): Average
- [Sensitive skin](https://lovi.care/skincare/sg/p/clinique/smart-clinical-repair-wrinkle-correcting-serum/for/sensitive-skin): Low
- [Acne-prone skin](https://lovi.care/skincare/sg/p/clinique/smart-clinical-repair-wrinkle-correcting-serum/for/acne-prone-skin): Average
- [Skin with dark spots](https://lovi.care/skincare/sg/p/clinique/smart-clinical-repair-wrinkle-correcting-serum/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/sg/p/clinique/smart-clinical-repair-wrinkle-correcting-serum/for/mature-skin): Average
- [Dry sensitive skin](https://lovi.care/skincare/sg/p/clinique/smart-clinical-repair-wrinkle-correcting-serum/for/dry-sensitive-skin): Average
- [Oily acne-prone skin](https://lovi.care/skincare/sg/p/clinique/smart-clinical-repair-wrinkle-correcting-serum/for/oily-acne-prone-skin): Average (this page)

## Key ingredients

Cl1870 Laser Focus Complex, Retinoid, Hyaluronic Acid Concentrate, Acetyl Hexapeptide-8, Palmitoyl Tripeptide-1

## What the research says

- Argireline treatment twice daily for 4 weeks produced a significant anti-wrinkle effect with 48.9% total efficacy and decreased skin roughness in Chinese subjects compared with 0% efficacy and no decrease in roughness in the placebo group. ([American Journal of Clinical Dermatology, 2013](https://pubmed.ncbi.nlm.nih.gov/23417317/))
- Treatment with cross-linked hyaluronic acid-based microneedle patches combined with acetyl hexapeptide-8 or epidermal growth factor significantly improved wrinkles and skin hydration compared to the patch alone in Korean females over 29 days. ([Annals of Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/33911590/))
- Acetyl hexapeptide-3 and tripeptide-10 citrulline demonstrated antiwrinkle efficacy and decreased transepidermal water loss in twenty-four healthy volunteers compared to control groups, though synergistic effects between the two peptides remained unclear. ([Journal of Cosmetic Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28150423/))
- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Topical application of a vitamin C-squalene bioconjugate significantly increased epidermal thickness, type III collagen production, and glycosaminoglycans production in human skin explants compared to free vitamin C and vitamin C-palmitate. ([Scientific Reports, 2020](https://pubmed.ncbi.nlm.nih.gov/33037252/))
- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))
- Daily topical acetyl hexapeptide-8 showed a trend toward a longer time until return to baseline Jankovic Blepharospasm Rating Scale scores compared to placebo (3.7 months vs. 3.0 months) in 24 patients with blepharospasm receiving botulinum toxin therapy. ([European Journal of Neurology, 2013](https://pubmed.ncbi.nlm.nih.gov/23146065/))
- Argireline applied twice daily for 4 weeks achieved a total anti-wrinkle efficiency of 48.9% and notably reduced wrinkle depth compared to placebo in Chinese subjects. ([Journal of Cosmetic and Laser Therapy, 2013](https://pubmed.ncbi.nlm.nih.gov/23607739/))
- Dissolving microneedles loaded with 3-O-ethyl ascorbic acid and acetyl hexapeptide-8 achieved higher cumulative transdermal delivery than aqueous solutions and significantly reduced photoaging signs while restoring oxidative balance in a UV/D-galactose-induced mouse model. ([International Journal of Biological Macromolecules, 2026](https://pubmed.ncbi.nlm.nih.gov/41628877/))
- A multi-modal methodology combining MALDI-MSI, in vivo RCM, echography, and histology revealed age-related decreases in extracellular matrix and epidermal-dermal junction proteins and undulation depth, while a blend of palmitoyl oligopeptide and palmitoyl tetrapeptide-7 improved subepidermal low-echogenic band thickness, density, and extracellular matrix structure compared to placebo. ([Journal of Cosmetic Dermatology, 2015](https://pubmed.ncbi.nlm.nih.gov/25817264/))
- Chronomodulated daytime application of baicalin and nighttime application of palmitoyl tripeptide-1 synergistically improved skin luminance by 16.29%, nasolabial fold depth by -36.35%, and firmness by 24.35% in 30 female participants. ([Journal of Cosmetic Dermatology, 2026](https://pubmed.ncbi.nlm.nih.gov/41527525/))
- Palmitoyl tetrapeptide-7, acetyl hexapeptide-8, palmitoyl tripeptide-1, and palmitoyl tetrapeptide-10 significantly increased type III collagen levels in human dermal fibroblasts following UV exposure, with their combination demonstrating a greater effect in vitro and enhancing type I, III, and IV collagen levels in ex vivo skin tissues compared to individual components. ([International Journal of Cosmetic Science, 2026](https://pubmed.ncbi.nlm.nih.gov/42683869/))

## What reviewers say

Based on a very large amount of data, users consistently praise this serum for its lightweight, fragrance-free formula that effectively hydrates and smooths skin texture without causing irritation, making it suitable for sensitive skin. While many report visible improvements in fine lines, plumpness, and overall radiance, some users note that deep wrinkles require consistent, long-term use to show significant changes and that the high price point is a consideration.

- Liked: Smoother skin (mostly mentioned)
- Liked: Hydrating and plumping (often mentioned)
- Liked: Lightweight absorption (often mentioned)
- Disliked: Expensive product (often mentioned)
- Liked: Gentle formula (sometimes noted)
- Liked: Reduces fine lines (sometimes noted)
- Disliked: Slow results (sometimes noted)
- Disliked: Pump issues (rarely noted)
- Disliked: Sun sensitivity (rarely noted)

## How to apply

- Could be used as part of your PM routine. Start 3 times a week and build up to daily use if your skin tolerates it well.
- Apply your serum after cleansing and toning, but before putting on your moisturizer.
- Gently press 2 to 3 drops of the serum into your skin and let it absorb for a minute.
- Apply the serum on clean, dry skin to help manage your blemishes safely.
- Do a patch test before your first use and avoid the delicate eye area.
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### How well does Clinique Smart Clinical Repair serum work for oily acne-prone skin?

This serum works reasonably well for your oily acne-prone skin, providing light hydration and smoothing texture without feeling heavy or causing irritation. A product of this type needs ingredients like niacinamide, propolis, and vitamin C to properly control excess oil, manage blemishes, and promote a healthy glow.
Sources: [American Journal of Clinical Dermatology, 2013](https://pubmed.ncbi.nlm.nih.gov/23417317/), [Annals of Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/33911590/)

### Which ingredients make this serum a good fit for oily acne-prone skin?

Dimethicone, polysilicone-11, glycerin, and sodium hyaluronate make this serum a good fit for oily acne-prone skin because they hydrate and smooth texture without feeling heavy or causing irritation. To work best for this skin type, a product of this type needs effective ingredients like niacinamide and propolis that control excess oil and manage acne concerns comfortably.
Sources: [American Journal of Clinical Dermatology, 2013](https://pubmed.ncbi.nlm.nih.gov/23417317/), [Annals of Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/33911590/)

### What does Cl1870 Laser Focus Complex do for oily acne-prone skin?

Cl1870 Laser Focus Complex helps oily, acne-prone skin by addressing breakouts and excess surface oils while supporting the skin barrier. An effective product for this skin type needs targeted ingredients that reduce blemishes and balance oil without causing irritation.
Sources: [Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/32697858/)

### What does Retinoid do for oily acne-prone skin?

Retinoid helps clear oily acne-prone skin by clearing out pores and calming redness. It is a reliable first-line choice that keeps skin smooth and manages breakouts over the long term.
Sources: [American Journal of Clinical Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/18973403/), [American Journal of Clinical Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30674002/)

### Where does this serum go in a skincare routine for oily acne-prone skin?

This treatment serum goes in the evening routine. Applying it at night helps keep things simple and provides extra safety around sun exposure.

### Can I use this serum with niacinamide, and in what order?

Yes, you can use this serum with niacinamide by applying niacinamide first and then this treatment once it absorbs. This routine is unlikely to cause irritation for your oily skin, though an oily acne-prone skin type needs oil-free hydrators, salicylic acid, and lightweight soothing ingredients for the best fit.

### How often should I use this serum?

You can use this treatment in the evening as part of your routine. This product of this type needs lightweight hydrators and soothing peptides to keep oily skin balanced and smooth without feeling heavy.
Sources: [American Journal of Clinical Dermatology, 2013](https://pubmed.ncbi.nlm.nih.gov/23417317/), [Annals of Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/33911590/)

### Can this serum clog pores, cause breakouts or purging for oily acne-prone skin?

This serum is unlikely to cause breakouts or clog pores on oily acne-prone skin because it has an excellent safety profile with soothing components and no harsh ingredients. However, because it is an average fit for your skin type, a product for oily and acne-prone skin needs lightweight hydrators and smoothing peptides that keep pores clear without feeling heavy.

### Is this serum fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for oily acne-prone skin

- [Neogen Dermalogy Real Vitamin C Serum](https://lovi.care/skincare/sg/p/neogen-dermalogy/real-vitamin-c-serum/for/oily-acne-prone-skin) — Superior fit — S$50.41 at Amazon
- [NEOGEN DERMALOGY REAL VITA C SERUM](https://lovi.care/skincare/sg/p/neogen-dermalogy/real-vita-c-serum/for/oily-acne-prone-skin) — High fit — S$50.41 at Amazon
- [Skin1004 Probio-Cica Intensive Ampoule](https://lovi.care/skincare/sg/p/skin1004/probio-cica-intensive-ampoule/for/oily-acne-prone-skin) — High fit — S$28.55 at Amazon

## Pairs well with

- Cleanser: [CeraVe Foaming Facial Cleanser](https://lovi.care/skincare/sg/p/cerave/foaming-facial-cleanser/for/oily-acne-prone-skin) — Superior fit — S$30.40 at Amazon
- Hydrating Toner: [TROIAREUKE H+Cocktail Purifying Ampoule Toner](https://lovi.care/skincare/sg/p/troiareuke/h-cocktail-purifying-ampoule-toner/for/oily-acne-prone-skin) — Superior fit — S$168.51 at Amazon
- SPF: [make p:rem UV Defense Me Blue Ray Sun Cream](https://lovi.care/skincare/sg/p/make-p-rem/uv-defense-me-blue-ray-sun-cream/for/oily-acne-prone-skin) — Superior fit — S$41.48 at Amazon

## Where to buy

No store in Singapore has a checked price for this product, so the page shows none.

## Ingredients

Water, Dimethicone, Isododecane, Butylene Glycol, Glycerin, Polysilicone-11, Ascorbyl Glucoside, Sodium Hyaluronate, Tocopheryl Acetate, Squalane, Hypnea Musciformis Extract Algae Extract, Gelidiella Acerosa Extract, Sigesbeckia Orientalis Extract, Helianthus Annuus Seed Extract Sunflower Seed Extract, Hordeum Vulgare Extract, Wheat Extract Germ Extract, Cucumis Sativus Fruit Extract, Caffeine, Acetyl Hexapeptide-8, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Palmitoyl Hexapeptide-12, Peg-10 Dimethicone, Glycyrrhetinic Acid, Whey Lactis Protéine Du Petit-Lait Protein, Isohexadecane, Propylene Glycol Dicaprate, Caprylyl Glycol, Hydroxypinacolone Retinoate, Acetyl Glucosamine, Cholesterol, Peg-8, Yeast Faex Extrait De Levure Extract, Peg-6, Dimethyl Isosorbide, Glyceryl Polymethacrylate, Polysorbate 20, Sodium Phosphate, Synthetic Fluorphlogopite, Polysorbate 80, Carbomer, Hexylene Glycol, Ammonium Acryloyldimethyltaurate Vp Copolymer, Acrylamide Sodium Acryloyldimethyltaurate Copolymer, Potassium Hydroxide, Tin Oxide, Disodium Phosphate, Citric Acid, Disodium Edta, Sodium Citrate, Phenoxyethanol, Potassium Sorbate, Titanium Dioxide Ci 77891
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/clinique/smart-clinical-repair-wrinkle-correcting-serum/for/oily-acne-prone-skin
- United Kingdom: https://lovi.care/skincare/uk/p/clinique/smart-clinical-repair-wrinkle-correcting-serum/for/oily-acne-prone-skin
- Ireland: https://lovi.care/skincare/ie/p/clinique/smart-clinical-repair-wrinkle-correcting-serum/for/oily-acne-prone-skin
- Germany: https://lovi.care/skincare/de/p/clinique/smart-clinical-repair-wrinkle-correcting-serum/for/oily-acne-prone-skin
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- Canada: https://lovi.care/skincare/ca/p/clinique/smart-clinical-repair-wrinkle-correcting-serum/for/oily-acne-prone-skin
- Australia: https://lovi.care/skincare/au/p/clinique/smart-clinical-repair-wrinkle-correcting-serum/for/oily-acne-prone-skin
- Singapore: https://lovi.care/skincare/sg/p/clinique/smart-clinical-repair-wrinkle-correcting-serum/for/oily-acne-prone-skin (this page)
- Saudi Arabia: https://lovi.care/skincare/sa/p/clinique/smart-clinical-repair-wrinkle-correcting-serum/for/oily-acne-prone-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/clinique/smart-clinical-repair-wrinkle-correcting-serum/for/oily-acne-prone-skin