# CLEARSTEM CELLRENEW Serum for dry skin

**Lovi Fit: High fit for dry skin.**
Dry Skin Fit: High · Effectiveness: High · Safety: High.

Page: https://lovi.care/skincare/sg/p/clearstem/cellrenew-serum/for/dry-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Singapore.

Brand: [CLEARSTEM](https://lovi.care/skincare/sg/brands/clearstem)
Category: [Serums and treatments](https://lovi.care/skincare/sg/best/serums)

This fit is calculated for the concerns frequently associated with dry skin: flakiness, tightness, dehydration, fine lines, and wrinkles. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

A great choice for dry skin; a few serums fit it even better.

## Why this fit

- Highly suitable for your dry skin due to the presence of sodium hyaluronate and panthenol B5, which offer humectant and barrier repair actions to hydrate and soothe. Camellia sinensis and aloe barbadensis further support hydration and provide antioxidant protection, addressing your dry or flaky skin concerns.
- The serum offers excellent skin treatment with antioxidants and sodium hyaluronate to hydrate and protect against environmental stressors, enhancing overall skin health.
- This formula is safe for your dry skin, containing no harsh ingredients and including soothing components like Camellia Sinensis and Aloe Barbadensis.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/sg/p/clearstem/cellrenew-serum/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/sg/p/clearstem/cellrenew-serum/for/dry-skin): High (this page)
- [Combination skin](https://lovi.care/skincare/sg/p/clearstem/cellrenew-serum/for/combination-skin): High
- [Sensitive skin](https://lovi.care/skincare/sg/p/clearstem/cellrenew-serum/for/sensitive-skin): Average
- [Acne-prone skin](https://lovi.care/skincare/sg/p/clearstem/cellrenew-serum/for/acne-prone-skin): Average
- [Skin with dark spots](https://lovi.care/skincare/sg/p/clearstem/cellrenew-serum/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/sg/p/clearstem/cellrenew-serum/for/mature-skin): High
- [Dry sensitive skin](https://lovi.care/skincare/sg/p/clearstem/cellrenew-serum/for/dry-sensitive-skin): High
- [Oily acne-prone skin](https://lovi.care/skincare/sg/p/clearstem/cellrenew-serum/for/oily-acne-prone-skin): Average

## Key ingredients

Sodium Hyaluronate, Ganoderma Lucidum, Bio-Available Collagen Cells Stem, Antioxidants, Curcuma Longa

## What the research says

- Topical dexpanthenol acts as a moisturizer, improves stratum corneum hydration, accelerates wound healing and epidermal regeneration, reduces erythema, and improves symptoms of skin irritation compared to vehicle or no pretreatment. ([American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/))
- A new topical panthenol-containing emollient significantly improved transepidermal water loss reduction, stratum corneum hydration, and intercellular lipid lamellae length compared with control in healthy subjects without negatively impacting bacterial viability. ([The Journal of Dermatological Treatment, 2017](https://pubmed.ncbi.nlm.nih.gov/27425824/))
- Topical application of (-)-epigallocatechin-3-gallate (EGCG) to human skin before UV irradiation decreases UV-induced production of hydrogen peroxide by 68-90% and nitric oxide by 30-100%, inhibits leukocyte infiltration and lipid peroxidation by 41-84%, and restores glutathione levels and glutathione peroxidase activity compared to UV exposure alone. ([Carcinogenesis, 2001](https://pubmed.ncbi.nlm.nih.gov/11181450/))
- Topical hyaluronic acid filler serum combined with Botulinum toxin type A lengthened the duration of the toxin's effect in reducing wrinkles compared to Botulinum toxin type A alone. ([Dermatologic Therapy, 2022](https://pubmed.ncbi.nlm.nih.gov/36200921/))
- Topical epigallocatechin-3-gallate application and zonal priming reduced scar thickness and VEGFA, decreased mast cells, increased M2 macrophages and hydration, and improved elasticity compared with placebo in human scars. ([The Journal of Investigative Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30822414/))
- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))
- Topical application of soap enriched with Ganoderma lucidum and goat's milk for 3 days resulted in almost complete regression of annular cutaneous sarcoidosis lesions in a 44-year-old male patient. ([Dermatology and Therapy, 2016](https://pubmed.ncbi.nlm.nih.gov/26868374/))
- Ganoderma lucidum polysaccharides at concentrations of 10, 20, and 40 ΓΖg/mL significantly increased fibroblast viability, migration, and CICP and TGF-Β1 expression compared to the control group, and external use in mice significantly increased wound healing rates and reduced healing time. ([Chinese Journal of Integrative Medicine, 2019](https://pubmed.ncbi.nlm.nih.gov/30552545/))
- Ethanolic extracts of Ganoderma lucidum rich in triterpenoids and phenolic acids exhibit antioxidant, anti-inflammatory, antityrosinase, antimicrobial, and cytotoxic effects, and can be successfully incorporated into topical cosmeceutical formulations while preserving their bioactivities. ([Food and Chemical Toxicology, 2017](https://pubmed.ncbi.nlm.nih.gov/28760544/))
- Topical application of TAC/Collagen postbiotics gel improved skin moisture score and inflammation index, and reduced porphyrins and brown spots in 20 volunteers with acne vulgaris. ([Journal of Cosmetic Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/35818134/))
- Topical collagen tripeptide application improved skin wrinkles, elasticity, and density while reducing advanced glycated end products in 22 Asian women over 4 weeks. ([International Journal of Molecular Sciences, 2022](https://pubmed.ncbi.nlm.nih.gov/35163025/))
- Marine collagen extracted from Greenland halibut skin showed a non-cytotoxic effect on fibroblast cells and provided a slight skin hydration effect when incorporated into cosmetic hydrogel formulations at dosages of 0.1, 0.25, and 0.5% in 23 healthy volunteers. ([Marine Drugs, 2023](https://pubmed.ncbi.nlm.nih.gov/36827098/))
- Topical application of curcumin or turmeric treats various skin conditions by leveraging antioxidant, anti-inflammatory, and antimicrobial properties. ([Skin Pharmacology and Physiology, 2023](https://pubmed.ncbi.nlm.nih.gov/38008088/))
- Topical formulations of curcumin target oxidative damage and inflammation to improve wound healing in animal models. ([Drug Discovery Today, 2017](https://pubmed.ncbi.nlm.nih.gov/28711364/))
- A curcumin-loaded spanlastic anti-aging gel utilizing formula F5 incorporated into 2% HPMC E50 demonstrated sustained release action, compatibility, and the ability to penetrate skin layers to a depth of about 112.5 um without signs of irritation. ([Saudi Pharmaceutical Journal, 2024](https://pubmed.ncbi.nlm.nih.gov/38178851/))

## What reviewers say

Based on a very large amount of data, users with acne-prone, sensitive, and reactive skin highly praise this product for calming inflammation, improving hydration, and supporting skin barrier repair. Many report smoother texture and reduced redness. Some users note it is a gentle, long-term support product rather than an overnight solution for deep-seated skin concerns.

- Liked: Acne-safe formula (mostly mentioned)
- Liked: Calms inflammation (often mentioned)
- Liked: Improves skin texture (often mentioned)
- Liked: Deeply hydrating (sometimes noted)
- Disliked: High price point (sometimes noted)
- Disliked: Slow visible results (sometimes noted)
- Disliked: Insufficient for severe acne (rarely noted)

## How to apply

- Apply this serum PM, starting 3×/week and working up to daily use as your skin adjusts.
- Place the serum after cleansing and toner, but right before your moisturizer.
- Gently press 2-3 drops of the serum into your skin and let it absorb for a minute.
- Apply the serum on slightly damp skin to help lock in extra moisture.
- Avoid the eye area and do a patch test before your first use.
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### What makes CLEARstem CELLRENEW Serum a great fit for dry skin?

CLEARstem CELLRENEW Serum is a great fit because it contains sodium hyaluronate and panthenol B5, which help hydrate and soothe dry skin. Camellia sinensis and aloe barbadensis provide extra moisture and protection against everyday stress without harsh ingredients.
Sources: [American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/), [The Journal of Dermatological Treatment, 2017](https://pubmed.ncbi.nlm.nih.gov/27425824/)

### Which ingredients make this serum a good fit for dry skin?

Sodium hyaluronate and panthenol B5 make this serum a great fit for your dry skin by pulling in moisture and repairing your skin barrier to keep it soft and calm. Camellia sinensis and aloe barbadensis also help boost hydration and protect against dryness or flaking.
Sources: [American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/), [The Journal of Dermatological Treatment, 2017](https://pubmed.ncbi.nlm.nih.gov/27425824/)

### What does Hyaluronic Acid do for dry skin?

Hyaluronic acid draws moisture into dry skin, giving an immediate and lasting boost in hydration that helps smooth out fine lines and soften rough patches. It is very gentle and unlikely to cause irritation while improving overall skin smoothness and plumpness.
Sources: [Dermatology and Therapy, 2021](https://pubmed.ncbi.nlm.nih.gov/34176098/), [Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/)

### What does Reishi Mushroom Extract do for dry skin?

Reishi mushroom extract helps calm dry skin by reducing cellular oxidative stress and protecting against damage caused by UV rays. It also helps prevent the breakdown of proteins in the skin to keep it looking healthy and smooth.
Sources: [Fitoterapia, 2025](https://pubmed.ncbi.nlm.nih.gov/40381851/)

### Where does this serum go in a skincare routine for dry skin?

This serum goes in your evening routine after cleansing and before your moisturizer. Putting it on at night helps keep things simple and protects your skin while it rests.

### Can I use this serum with retinol, and in what order?

You can use this serum with retinol by applying the serum first to hydrate and soothe, followed by your retinol. This approach helps minimize dryness and irritation while supporting your overall skin health.
Sources: [Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38102855/)

### How often should I use this serum?

This serum is used in the evening as part of your routine for dry skin. It contains sodium hyaluronate and panthenol B5, which help hydrate and soothe dry or flaky skin.
Sources: [American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/), [The Journal of Dermatological Treatment, 2017](https://pubmed.ncbi.nlm.nih.gov/27425824/)

### Can this serum clog pores, cause breakouts or purging for dry skin?

This serum is unlikely to clog pores, cause breakouts, or lead to purging on dry skin. It contains gentle, soothing ingredients like panthenol and aloe, and has a very safe profile without harsh components that typically trigger irritation.
Sources: [American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/), [The Journal of Dermatological Treatment, 2017](https://pubmed.ncbi.nlm.nih.gov/27425824/)

### Is this serum fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for dry skin

- [ma:nyo Bifida Biome Complex Ampoule](https://lovi.care/skincare/sg/p/ma-nyo/bifida-biome-complex-ampoule/for/dry-skin) — Superior fit — S$40.09 at Amazon
- [SKIN1004 Madagascar Centella Tone Brightening Capsule Ampoule](https://lovi.care/skincare/sg/p/skin1004/madagascar-centella-tone-brightening-capsule-ampoule/for/dry-skin) — Superior fit — S$54.11 at Amazon
- [Neogen Dermalogy Real Vitamin C Serum](https://lovi.care/skincare/sg/p/neogen-dermalogy/real-vitamin-c-serum/for/dry-skin) — Superior fit — S$50.41 at Amazon

## Pairs well with

- Cleanser: [CeraVe Hydrating Cleanser](https://lovi.care/skincare/sg/p/cerave/hydrating-facial-cleanser/for/dry-skin) — Superior fit — S$25.06 at Amazon
- Hydrating Toner: [COSRX Propolis Synergy Toner](https://lovi.care/skincare/sg/p/cosrx/propolis-synergy-toner/for/dry-skin) — Superior fit — S$41.07 at Amazon
- Moisturizer: [d'Alba First Spray Serum](https://lovi.care/skincare/sg/p/d-alba/first-spray-serum/for/dry-skin) — Superior fit — S$25.94 at Amazon

## Where to buy

No store in Singapore has a checked price for this product, so the page shows none.

## Ingredients

Antioxidants, Camellia Sinensis, Sodium Hyaluronate, Ganoderma Lucidum, Curcuma Longa, Trifolium Pratense, Peppermint Essence, Curcuma Extract, Aloe Barbadensis, Panthenol B5, Bio-Available Collagen Cells Stem, Kunzea Pomifera Fruit Extract
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/clearstem/cellrenew-serum/for/dry-skin
- United Kingdom: https://lovi.care/skincare/uk/p/clearstem/cellrenew-serum/for/dry-skin
- Ireland: https://lovi.care/skincare/ie/p/clearstem/cellrenew-serum/for/dry-skin
- Germany: https://lovi.care/skincare/de/p/clearstem/cellrenew-serum/for/dry-skin
- France: https://lovi.care/skincare/fr/p/clearstem/cellrenew-serum/for/dry-skin
- Italy: https://lovi.care/skincare/it/p/clearstem/cellrenew-serum/for/dry-skin
- Netherlands: https://lovi.care/skincare/nl/p/clearstem/cellrenew-serum/for/dry-skin
- Spain: https://lovi.care/skincare/es/p/clearstem/cellrenew-serum/for/dry-skin
- Canada: https://lovi.care/skincare/ca/p/clearstem/cellrenew-serum/for/dry-skin
- Australia: https://lovi.care/skincare/au/p/clearstem/cellrenew-serum/for/dry-skin
- Singapore: https://lovi.care/skincare/sg/p/clearstem/cellrenew-serum/for/dry-skin (this page)
- Saudi Arabia: https://lovi.care/skincare/sa/p/clearstem/cellrenew-serum/for/dry-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/clearstem/cellrenew-serum/for/dry-skin