# CELL BY CELL Soft Enzyme Powder for sensitive skin

**Lovi Fit: Average fit for sensitive skin.**
Normal Skin Fit: High · Effectiveness: Average · Safety: High.

Page: https://lovi.care/skincare/sg/p/cell-by-cell/soft-enzyme-powder/for/sensitive-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Singapore.

Brand: CELL BY CELL
Category: [Exfoliants](https://lovi.care/skincare/sg/best/exfoliators)

This fit is calculated for the concerns frequently associated with sensitive skin: redness, stinging, and reactions to new products. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for sensitive skin; other products fit it better.

## Why this fit

- Offers moderate benefits for your normal skin with sensitivity, as Aloe Barbadensis Leaf Juice and Allantoin provide soothing and barrier-repairing actions to help calm redness and irritation.
- The cleansing agents Sodium Cocoyl Isethionate and Sodium Lauroyl Glutamate effectively remove impurities without compromising your skin's natural balance.
- The product is safe for your skin, with no risks of irritation due to the absence of harsh or prohibited ingredients.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/sg/p/cell-by-cell/soft-enzyme-powder/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/sg/p/cell-by-cell/soft-enzyme-powder/for/dry-skin): Average
- [Combination skin](https://lovi.care/skincare/sg/p/cell-by-cell/soft-enzyme-powder/for/combination-skin): Average
- [Sensitive skin](https://lovi.care/skincare/sg/p/cell-by-cell/soft-enzyme-powder/for/sensitive-skin): Average (this page)
- [Acne-prone skin](https://lovi.care/skincare/sg/p/cell-by-cell/soft-enzyme-powder/for/acne-prone-skin): Average
- [Skin with dark spots](https://lovi.care/skincare/sg/p/cell-by-cell/soft-enzyme-powder/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/sg/p/cell-by-cell/soft-enzyme-powder/for/mature-skin): Average
- [Dry sensitive skin](https://lovi.care/skincare/sg/p/cell-by-cell/soft-enzyme-powder/for/dry-sensitive-skin): Average
- [Oily acne-prone skin](https://lovi.care/skincare/sg/p/cell-by-cell/soft-enzyme-powder/for/oily-acne-prone-skin): Average

## Key ingredients

Sodium Cocoyl Isethionate, Aloe Barbadensis Leaf Juice, Collagen, Allantoin, Opuntia Ficus-Indica Stem Extract

## What the research says

- A cream combining propolis, tea tree oil, and Aloe vera reduced erythema scars, acne severity index, and total lesion count better than erythromycin cream in sixty patients with mild to moderate acne vulgaris compared to placebo. ([Clinical Pharmacology, 2018](https://pubmed.ncbi.nlm.nih.gov/30588129/))
- Sodium cocoyl isethionate micelles are too large to penetrate stratum corneum aqueous pores, resulting in significant steric hindrance that prevents skin barrier perturbation and explains its skin mildness. ([Journal of Cosmetic Science, 2007](https://pubmed.ncbi.nlm.nih.gov/17598025/))
- Opuntia ficus-indica extract and its isorhamnetin-glucosyl-rhamnoside suppressed nitric oxide, COX-2, TNF-alpha, and IL-6 production in vitro and inhibited croton oil-induced ear edema in vivo. ([BioMed Research International, 2015](https://pubmed.ncbi.nlm.nih.gov/25821823/))
- Topical aloe vera gel significantly accelerated split-thickness skin graft donor-site healing compared to placebo in 12 patients, but showed no significant difference in pain relief. ([Plastic and Reconstructive Surgery, 2018](https://pubmed.ncbi.nlm.nih.gov/29649056/))
- Topical application of Aloe vera cream reduced postoperative pain at rest and during defecation, accelerated wound healing at two weeks, and decreased analgesic requirements in patients after open hemorrhoidectomy compared to placebo. ([Journal of Alternative and Complementary Medicine, 2010](https://pubmed.ncbi.nlm.nih.gov/20569031/))
- Formulations containing 0.10%, 0.25%, and 0.50% freeze-dried Aloe vera extract increased stratum corneum water content compared with the vehicle in 20 female subjects, while transepidermal water loss was not modified. ([Skin Research and Technology, 2006](https://pubmed.ncbi.nlm.nih.gov/17026654/))
- Topical application of TAC/Collagen postbiotics gel improved skin moisture score and inflammation index, and reduced porphyrins and brown spots in 20 volunteers with acne vulgaris. ([Journal of Cosmetic Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/35818134/))
- Topical collagen tripeptide application improved skin wrinkles, elasticity, and density while reducing advanced glycated end products in 22 Asian women over 4 weeks. ([International Journal of Molecular Sciences, 2022](https://pubmed.ncbi.nlm.nih.gov/35163025/))
- Marine collagen extracted from Greenland halibut skin showed a non-cytotoxic effect on fibroblast cells and provided a slight skin hydration effect when incorporated into cosmetic hydrogel formulations at dosages of 0.1, 0.25, and 0.5% in 23 healthy volunteers. ([Marine Drugs, 2023](https://pubmed.ncbi.nlm.nih.gov/36827098/))
- Topical gel containing chitosan, 0.2% chlorhexidine, allantoin and dexpanthenol did not improve postoperative comfort regarding swelling and pain, but improved the wound's aesthetic appearance following impacted lower third molar extraction compared to no gel. ([Medicina Oral, Patologia Oral Y Cirugia Bucal, 2016](https://pubmed.ncbi.nlm.nih.gov/27475700/))
- A topical gel containing chitosan, chlorhexidine, allantoin, and dexpanthenol significantly reduced postoperative pain, trismus, swelling, and analgesic consumption, while improving wound healing after third molar surgery compared to a placebo. ([Medicina Oral, Patologia Oral Y Cirugia Bucal, 2020](https://pubmed.ncbi.nlm.nih.gov/32683390/))
- An overnight patch containing Allium cepa extract and allantoin safely promotes scar healing after dermatologic surgery, resulting in significantly greater reductions in observer- and patient-assessed POSAS scores compared to no treatment. ([Aesthetic Plastic Surgery, 2018](https://pubmed.ncbi.nlm.nih.gov/29948103/))
- Opuntia ficus-indica extract activated AHR-NRF2 signaling, inhibited reactive oxygen species generation, and upregulated filaggrin and loricrin expression in human keratinocytes. ([Journal of Medicinal Food, 2015](https://pubmed.ncbi.nlm.nih.gov/26061570/))
- Pre-treating normal human keratinocytes with an Opuntia ficus-indica cladode water extract protected against UVA-induced oxidative stress and apoptosis by inhibiting free radicals, lipid peroxidation, and GSH depletion. ([Bioorganic & Medicinal Chemistry Letters, 2017](https://pubmed.ncbi.nlm.nih.gov/29107540/))
- Mucilaginous and methanol extracts of Opuntia ficus-indica flowers accelerated wound contraction and improved cutaneous repair compared to the control group in rats. ([International Journal of Biological Macromolecules, 2015](https://pubmed.ncbi.nlm.nih.gov/26306411/))

## What reviewers say

Based on limited data, users consistently describe this cleanser as an exceptionally gentle powder-to-foam exfoliant that effectively smooths skin texture without stripping moisture. It is frequently recommended for sensitive, acne-prone, and oily skin types, with many users reporting a reduction in small bumps and a baby-soft finish after use.

- Liked: Gentle exfoliation (mostly mentioned)
- Liked: Skin texture improvement (often mentioned)
- Liked: Deep cleansing (sometimes noted)
- Liked: Non-stripping (sometimes noted)
- Disliked: Packaging design (sometimes noted)
- Disliked: Clumping issues (rarely noted)
- Disliked: Messy application (rarely noted)
- Disliked: Price vs. quantity (rarely noted)

## How to apply

- Could be used as part of your PM routine once a week. Start slowly and increase usage only if your skin feels comfortable.
- Apply this enzyme powder cleanser after your regular cleanser, and before your hydrating toner and moisturizer.
- Pour a small amount into wet hands, lather into a foam, and gently massage onto your face without harsh rubbing.
- For sensitive skin, apply this product on slightly damp skin to ensure better tolerance and comfort.
- Avoid the eye area and do a patch test before your very first use to prevent irritation.
- Video: https://storage.pora.ai/2d8db6e67371d665a6a7736b5ed5d762.mp4

## Questions and answers

### How well does CELL BY CELL Soft Enzyme Powder work for sensitive skin?

This product works moderately well for sensitive skin, as aloe vera and allantoin help calm redness and irritation while gentle cleansers remove impurities without disrupting the skin. To work best for sensitive skin, this type of product needs soothing plant extracts and gentle exfoliating agents that lift away impurities without any harsh or irritating effects.

### Which ingredients make this cleanser a good fit for sensitive skin?

Aloe Barbadensis Leaf Juice and Allantoin make this cleanser a good fit because they help calm redness and irritation, while Sodium Cocoyl Isethionate and Sodium Lauroyl Glutamate gently remove impurities without upsetting your skin's natural balance. An enzyme powder cleanser for sensitive skin needs soothing plant extracts and gentle cleansing agents that lift impurities without stripping moisture, along with extra hydrating ingredients to keep the skin calm and comfortable.

### What does Sodium Cocoyl Isethionate do for sensitive skin?

Sodium cocoyl isethionate helps cleanse sensitive skin without causing dryness or irritation. Its large molecules are unable to slip past the skin barrier, which makes it very gentle and unlikely to cause discomfort.
Sources: [Journal of Cosmetic Science, 2007](https://pubmed.ncbi.nlm.nih.gov/17598025/), [Journal of Cosmetic Dermatology, 2018](https://pubmed.ncbi.nlm.nih.gov/29231284/)

### What does Aloe Vera Leaf Juice do for sensitive skin?

Aloe Vera Leaf Juice helps calm sensitive skin and keeps it hydrated without causing irritation. Studies show it supports skin comfort and can safely improve moisture levels.
Sources: [Skin Research and Technology, 2006](https://pubmed.ncbi.nlm.nih.gov/17026654/), [Journal of Cosmetic Dermatology, 2025](https://pubmed.ncbi.nlm.nih.gov/40682399/)

### Where does it go in a skincare routine for sensitive skin?

This enzyme powder is used once a week as an exfoliating step in a weekly evening routine for sensitive skin. To truly thrive, sensitive skin needs gentle cleansers and soothing ingredients like aloe and allantoin to calm redness while keeping the skin barrier strong.

### Can I use this cleanser with retinol, and in what order?

You can use this cleanser in your routine when using retinol, but use it on separate days or times rather than layering them directly to avoid overwhelming sensitive skin. Because enzyme powder is a deeper exfoliant, sensitive skin needs a cleanser and moisturizer with soothing ingredients like aloe and allantoin to help calm irritation and maintain a healthy barrier.
Sources: [Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38102855/)

### How often should I use it?

Start by using this enzyme powder once a week, and if your skin tolerates it well and shows good results, you can carefully use it more often. A product of this type for sensitive skin needs calming plant extracts and gentle cleansing agents that soothe redness while keeping your skin balanced and comfortable.

### Can this cleanser clog pores, cause breakouts or purging for sensitive skin?

CELL BY CELL Soft Enzyme Powder is unlikely to clog pores or cause breakouts for sensitive skin, as its gentle cleansing agents remove impurities without disturbing the skin barrier. However, because it is an average fit for this skin type, sensitive skin needs a cleanser packed with extra soothing ingredients like aloe and allantoin alongside ultra-mild cleansers to prevent any potential irritation.

### Is it fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for sensitive skin

- [Leegeehaam Life Enzyme Wash](https://lovi.care/skincare/sg/p/leegeehaam/life-enzyme-wash/for/sensitive-skin) — High fit — S$29.18 at Amazon
- [By Wishtrend Green Tea & Enzyme Powder Wash](https://lovi.care/skincare/sg/p/by-wishtrend/green-tea-and-enzyme-powder-wash/for/sensitive-skin) — High fit — S$15.41 at YesStyle
- [NEEDLY Mild Enzyme Cleansing Powder](https://lovi.care/skincare/sg/p/needly/mild-enzyme-cleansing-powder/for/sensitive-skin) — High fit — S$18.03 at YesStyle

## Pairs well with

- Cleanser: [Fresh Soy Face Cleanser](https://lovi.care/skincare/sg/p/fresh/soy-face-cleanser/for/sensitive-skin) — Superior fit — S$30.00 at Amazon
- Soothing Toner: [One Thing Centella Asiatica Extract Toner](https://lovi.care/skincare/sg/p/one-thing/centella-asiatica-extract-toner/for/sensitive-skin) — Superior fit — S$30.07 at Amazon
- Moisturizer with Sun Protection: [ISDIN Eryfotona Actinica SPF 50+](https://lovi.care/skincare/sg/p/isdin/eryfotona-actinica-spf-50/for/sensitive-skin) — Superior fit — S$110.01 at Amazon

## Where to buy

No store in Singapore has a checked price for this product, so the page shows none.

## Ingredients

Zea Mays Starch, Sodium Cocoyl Isethionate, Sodium Lauroyl Glutamate, Aloe Barbadensis Leaf Juice, Opuntia Ficus-Indica Stem Extract, Allantoin, Collagen, Sorbitol, Ascorbyl Palmitate, Isopropyl Palmitate, Grapefruit Seed Extract, Pollen Extract, Titanium Dioxide, Citric Acid, Disodium Edta
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/cell-by-cell/soft-enzyme-powder/for/sensitive-skin
- United Kingdom: https://lovi.care/skincare/uk/p/cell-by-cell/soft-enzyme-powder/for/sensitive-skin
- Ireland: https://lovi.care/skincare/ie/p/cell-by-cell/soft-enzyme-powder/for/sensitive-skin
- Germany: https://lovi.care/skincare/de/p/cell-by-cell/soft-enzyme-powder/for/sensitive-skin
- France: https://lovi.care/skincare/fr/p/cell-by-cell/soft-enzyme-powder/for/sensitive-skin
- Italy: https://lovi.care/skincare/it/p/cell-by-cell/soft-enzyme-powder/for/sensitive-skin
- Netherlands: https://lovi.care/skincare/nl/p/cell-by-cell/soft-enzyme-powder/for/sensitive-skin
- Spain: https://lovi.care/skincare/es/p/cell-by-cell/soft-enzyme-powder/for/sensitive-skin
- Canada: https://lovi.care/skincare/ca/p/cell-by-cell/soft-enzyme-powder/for/sensitive-skin
- Australia: https://lovi.care/skincare/au/p/cell-by-cell/soft-enzyme-powder/for/sensitive-skin
- Singapore: https://lovi.care/skincare/sg/p/cell-by-cell/soft-enzyme-powder/for/sensitive-skin (this page)
- Saudi Arabia: https://lovi.care/skincare/sa/p/cell-by-cell/soft-enzyme-powder/for/sensitive-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/cell-by-cell/soft-enzyme-powder/for/sensitive-skin