# Bonajour Extreme Spot Serum for combination skin

**Lovi Fit: High fit for combination skin.**
Combination Skin Fit: High · Effectiveness: High · Safety: High.

Page: https://lovi.care/skincare/sg/p/bonajour/extreme-spot-serum/for/combination-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Singapore.

Brand: Bonajour
Category: [Serums and treatments](https://lovi.care/skincare/sg/best/serums)

This fit is calculated for the concerns frequently associated with combination skin: an oily T-zone, enlarged pores, and dry cheeks. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

One of the best serums for combination skin.

## Why this fit

- Offers excellent treatment for acne-prone skin as Centella Asiatica Extract and Salix Nigra Bark Extract reduce acne lesions and blemishes, while Niacinamide and Salix Nigra Bark Extract control sebum and provide mild exfoliation for your combination skin.
- Glycerin and Salix Nigra Bark Extract offer keratolytic and humectant actions, making it highly suitable for your combination skin type.
- The formula is safe for your combination skin, with no risks of irritation due to the absence of prohibited or harsh ingredients.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/sg/p/bonajour/extreme-spot-serum/for/oily-skin): High
- [Dry skin](https://lovi.care/skincare/sg/p/bonajour/extreme-spot-serum/for/dry-skin): Superior
- [Combination skin](https://lovi.care/skincare/sg/p/bonajour/extreme-spot-serum/for/combination-skin): High (this page)
- [Sensitive skin](https://lovi.care/skincare/sg/p/bonajour/extreme-spot-serum/for/sensitive-skin): High
- [Acne-prone skin](https://lovi.care/skincare/sg/p/bonajour/extreme-spot-serum/for/acne-prone-skin): High
- [Skin with dark spots](https://lovi.care/skincare/sg/p/bonajour/extreme-spot-serum/for/dark-spots): High
- [Mature skin](https://lovi.care/skincare/sg/p/bonajour/extreme-spot-serum/for/mature-skin): High
- [Dry sensitive skin](https://lovi.care/skincare/sg/p/bonajour/extreme-spot-serum/for/dry-sensitive-skin): High
- [Oily acne-prone skin](https://lovi.care/skincare/sg/p/bonajour/extreme-spot-serum/for/oily-acne-prone-skin): High

## Key ingredients

Centella Asiatica Extract, Niacinamide, Glycosaminoglycans, Allantoin, Akebia Quinata Extract

## What the research says

- Co-delivery of paeonol and madecassoside via nanoemulsions improved transdermal delivery, promoted barrier repair proteins, inhibited inflammatory cytokine secretion in cellular and 3D models, and reduced transepidermal water loss and acne in human facial skin compared to free components. ([Molecules, 2023](https://pubmed.ncbi.nlm.nih.gov/37446936/))
- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Topical application of 0.05% w/w ECa 233 gel reduced erythema index by 0.03 U and improved early crusting and general wound appearance compared to placebo in thirty individuals undergoing facial laser resurfacing. ([Journal of Alternative and Complementary Medicine, 2020](https://pubmed.ncbi.nlm.nih.gov/32310680/))
- Moisturizer containing 5% panthenol, madecassoside, and copper-zinc-manganese decreased adverse reactions and downtime after ablative fractional carbon dioxide laser resurfacing with comparable efficacy to 0.02% triamcinolone acetonide cream in 20 subjects. ([Journal of Cosmetic Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30945430/))
- Topical treatment with 5% vitamin C and 0.1% madecassoside significantly improved clinical scores for wrinkles, suppleness, firmness, roughness, and skin hydration, along with functional and structural remodeling of the elastic fiber network in 20 female volunteers with photoaged skin after 6 months compared to baseline. ([Experimental Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/18503551/))
- Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33103316/))
- Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women. ([The Journal of Investigative Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/17882270/))
- Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging. ([Dermatologic Surgery, 2005](https://pubmed.ncbi.nlm.nih.gov/16029679/))
- Topical treatment with sphingolipids and glycosaminoglycans attenuated clinical worsening and reduced CADESI and PVAS scores compared to the untreated control group in house dust mite-allergic beagle dogs. ([BMC Veterinary Research, 2020](https://pubmed.ncbi.nlm.nih.gov/32197613/))
- Glycosaminoglycans restored type I collagen synthesis, reduced matrix metalloproteinase-1 levels, upregulated tissue inhibitor of metalloproteinase-1, and attenuated apoptosis in tumor necrosis factor-alpha-stimulated human dermal fibroblasts by inhibiting extracellular signal-regulated kinase/activator protein-1 signaling. ([International Journal of Molecular Medicine, 2018](https://pubmed.ncbi.nlm.nih.gov/29436595/))
- Fraction 3 of glycosaminoglycans from Liparis tessellatus eggs showed 20.1% tyrosinase inhibition at 50mg/mL and effective skin regeneration activities at 200mg/mL against skin fibroblast CCD-986sk cell lines. ([International Journal of Biological Macromolecules, 2017](https://pubmed.ncbi.nlm.nih.gov/28917941/))
- Topical gel containing chitosan, 0.2% chlorhexidine, allantoin and dexpanthenol did not improve postoperative comfort regarding swelling and pain, but improved the wound's aesthetic appearance following impacted lower third molar extraction compared to no gel. ([Medicina Oral, Patologia Oral Y Cirugia Bucal, 2016](https://pubmed.ncbi.nlm.nih.gov/27475700/))
- A topical gel containing chitosan, chlorhexidine, allantoin, and dexpanthenol significantly reduced postoperative pain, trismus, swelling, and analgesic consumption, while improving wound healing after third molar surgery compared to a placebo. ([Medicina Oral, Patologia Oral Y Cirugia Bucal, 2020](https://pubmed.ncbi.nlm.nih.gov/32683390/))
- An overnight patch containing Allium cepa extract and allantoin safely promotes scar healing after dermatologic surgery, resulting in significantly greater reductions in observer- and patient-assessed POSAS scores compared to no treatment. ([Aesthetic Plastic Surgery, 2018](https://pubmed.ncbi.nlm.nih.gov/29948103/))
- Akebia quinata fruit extract reduced CML expression, stimulated fibrillin-1 expression, and decreased deep crow's feet wrinkle depth in humans compared to treatment without the extract. ([Nutrients, 2015](https://pubmed.ncbi.nlm.nih.gov/26569300/))

## What reviewers say

Based on limited data, users with acne-prone and sensitive skin find this serum effective for calming breakouts and fading post-acne marks. It is frequently praised for soothing redness and providing hydration. A notable number of users report a temporary stinging sensation upon application and a sticky finish that takes time to absorb.

- Liked: Calms acne (mostly mentioned)
- Liked: Fades dark spots (often mentioned)
- Disliked: Sticky texture (often mentioned)
- Liked: Deeply hydrating (sometimes noted)
- Disliked: Stinging sensation (sometimes noted)
- Disliked: Poor packaging (rarely noted)

## How to apply

- Use your serum as part of your PM routine. Start using it 3 times a week and move to daily use if your skin likes it.
- Apply the serum after cleansing and toner, and right before your moisturizer.
- Gently press 2-3 drops of the serum into your skin and wait a minute ⏳for it to soak in.
- Apply the serum on clean and dry skin since your skin is not sensitive.
- Always do a patch test before using the serum for the first time, and avoid the eye area .
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### What makes Bonajour Extreme Spot Serum a great fit for combination skin?

Bonajour Extreme Spot Serum is a great fit for combination skin because Centella Asiatica Extract and Salix Nigra Bark Extract reduce blemishes while Niacinamide helps control oily shine. The formula is very safe and unlikely to cause irritation.
Sources: [Molecules, 2023](https://pubmed.ncbi.nlm.nih.gov/37446936/), [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Which ingredients make this serum a good fit for combination skin?

Centella Asiatica Extract and Salix Nigra Bark Extract help reduce acne and blemishes, while Niacinamide and Salix Nigra Bark Extract control oil and provide mild exfoliation for your combination skin. Additionally, Glycerin and Salix Nigra Bark Extract keep your skin hydrated and smooth.
Sources: [Molecules, 2023](https://pubmed.ncbi.nlm.nih.gov/37446936/), [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### What does Centella Asiatica Extract do for combination skin?

Centella Asiatica Extract helps balance combination skin by boosting moisture levels while keeping redness and irritation calm. It also supports skin barrier repair to help maintain smooth and healthy skin overall.
Sources: [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/), [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### What does Niacinamide do for combination skin?

Niacinamide helps balance oily areas by reducing excess shine and pore size while keeping dry patches hydrated and smooth. It also works to calm redness and even out skin tone, making it very suitable for combination skin.
Sources: [The British Journal of Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12100180/), [Antioxidants, 2021](https://pubmed.ncbi.nlm.nih.gov/34439563/)

### Where does it go in a skincare routine for combination skin?

Apply this treatment in the evening as part of your routine. This timing keeps things simple and provides extra safety around sun exposure.

### Can I use this serum with retinol, and in what order?

You can use this serum with retinol by applying the serum first in your evening routine, as the formula is safe and unlikely to cause irritation on combination skin. Using soothing ingredients like Centella Asiatica Extract alongside your routine helps keep skin calm while managing breakouts.
Sources: [Molecules, 2023](https://pubmed.ncbi.nlm.nih.gov/37446936/), [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### How often should I use it?

Use this serum in your evening routine, applying it once a day for your combination skin. The formula is safe for your skin with no risks of irritation, helping to control oil and blemishes effectively.
Sources: [Molecules, 2023](https://pubmed.ncbi.nlm.nih.gov/37446936/), [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Can this serum clog pores, cause breakouts or purging for combination skin?

This serum is unlikely to clog pores or cause breakouts on your combination skin because Centella Asiatica Extract and Niacinamide help control oil and soothe blemishes safely. The formula has a very low risk of irritation, though some users report a sticky feel or mild stinging.
Sources: [Molecules, 2023](https://pubmed.ncbi.nlm.nih.gov/37446936/), [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Is it fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for combination skin

- [Skin1004 Probio-Cica Intensive Ampoule](https://lovi.care/skincare/sg/p/skin1004/probio-cica-intensive-ampoule/for/combination-skin) — High fit — S$28.55 at Amazon
- [Neogen Dermalogy Real Vitamin C Serum](https://lovi.care/skincare/sg/p/neogen-dermalogy/real-vitamin-c-serum/for/combination-skin) — High fit — S$50.41 at Amazon
- [NEOGEN DERMALOGY REAL VITA C SERUM](https://lovi.care/skincare/sg/p/neogen-dermalogy/real-vita-c-serum/for/combination-skin) — High fit — S$50.41 at Amazon

## Pairs well with

- Cleanser: [Fresh Soy Face Cleanser](https://lovi.care/skincare/sg/p/fresh/soy-face-cleanser/for/combination-skin) — Superior fit — S$30.00 at Amazon
- Hydrating Toner: [Whamisa Organic Flowers Toner Deep Rich](https://lovi.care/skincare/sg/p/whamisa/organic-flowers-toner-deep-rich/for/combination-skin) — Superior fit — S$64.81 at Amazon
- SPF: [CeraVe AM Facial Moisturizing Lotion](https://lovi.care/skincare/sg/p/cerave/am-facial-moisturizing-lotion-spf-30/for/combination-skin) — Superior fit — S$28.72 at Amazon

## Where to buy

- Amazon.sg: S$41.48 (https://www.amazon.sg/dp/B07588ML8Q?tag=lovi-care-web-product0e-22&linkCode=osi&th=1&psc=1)
- YesStyle: S$39.53 (https://www.yesstyle.com/en/bonajour-extreme-spot-serum-jumbo-100ml/info.html/pid.1115269997?curr=SGD&rco=SG)
Prices checked 14 Oct – 5 Nov 2026.

## Ingredients

Centella Asiatica Extract, Glycerin, Water, Niacinamide, Akebia Quinata Extract, Nicotinoyl Dipeptide-23, Glycosaminoglycans, Salix Nigra Bark Extract Willow Bark Extract, Aminobutyric Acid, Allantoin, 1,2-Hexanediol, Ammonium Acryloyldimethyltaurate Vp Copolymer, Butylene Glycol, Pentylene Glycol, Caprylyl Glycol, Xanthan Gum, Zanthoxylum Piperitum Fruit Extract, Pulsatilla Koreana Extract, Usnea Barbata Extract
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/bonajour/extreme-spot-serum/for/combination-skin
- United Kingdom: https://lovi.care/skincare/uk/p/bonajour/extreme-spot-serum/for/combination-skin
- Ireland: https://lovi.care/skincare/ie/p/bonajour/extreme-spot-serum/for/combination-skin
- Germany: https://lovi.care/skincare/de/p/bonajour/extreme-spot-serum/for/combination-skin
- France: https://lovi.care/skincare/fr/p/bonajour/extreme-spot-serum/for/combination-skin
- Italy: https://lovi.care/skincare/it/p/bonajour/extreme-spot-serum/for/combination-skin
- Netherlands: https://lovi.care/skincare/nl/p/bonajour/extreme-spot-serum/for/combination-skin
- Spain: https://lovi.care/skincare/es/p/bonajour/extreme-spot-serum/for/combination-skin
- Canada: https://lovi.care/skincare/ca/p/bonajour/extreme-spot-serum/for/combination-skin
- Australia: https://lovi.care/skincare/au/p/bonajour/extreme-spot-serum/for/combination-skin
- Singapore: https://lovi.care/skincare/sg/p/bonajour/extreme-spot-serum/for/combination-skin (this page)
- Saudi Arabia: https://lovi.care/skincare/sa/p/bonajour/extreme-spot-serum/for/combination-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/bonajour/extreme-spot-serum/for/combination-skin