# Bayer Skinoren Cream 20% for combination skin

**Lovi Fit: High fit for combination skin.**
Combination Skin Fit: High · Effectiveness: Average · Safety: High.

Page: https://lovi.care/skincare/sg/p/bayer/skinoren-cream-20/for/combination-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Singapore.

Brand: [Bayer](https://lovi.care/skincare/sg/brands/bayer)
Category: [Serums and treatments](https://lovi.care/skincare/sg/best/serums)

This fit is calculated for the concerns frequently associated with combination skin: an oily T-zone, enlarged pores, and dry cheeks. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

One of the best serums for combination skin.

## Why this fit

- Offers excellent treatment for acne-prone skin due to the high concentration of azelaic acid, which effectively reduces acne lesions and blemishes, while glycerin provides humectant action suitable for combination skin.
- The anti-inflammatory and keratolytic actions of azelaic acid also offer moderate benefits for controlling oily shine and improving skin texture.
- The safety profile is excellent, with no risks of irritation for your combination skin due to the absence of prohibited or harsh ingredients.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/sg/p/bayer/skinoren-cream-20/for/oily-skin): High
- [Dry skin](https://lovi.care/skincare/sg/p/bayer/skinoren-cream-20/for/dry-skin): Low
- [Combination skin](https://lovi.care/skincare/sg/p/bayer/skinoren-cream-20/for/combination-skin): High (this page)
- [Sensitive skin](https://lovi.care/skincare/sg/p/bayer/skinoren-cream-20/for/sensitive-skin): High
- [Acne-prone skin](https://lovi.care/skincare/sg/p/bayer/skinoren-cream-20/for/acne-prone-skin): High
- [Skin with dark spots](https://lovi.care/skincare/sg/p/bayer/skinoren-cream-20/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/sg/p/bayer/skinoren-cream-20/for/mature-skin): Average
- [Dry sensitive skin](https://lovi.care/skincare/sg/p/bayer/skinoren-cream-20/for/dry-sensitive-skin): Low
- [Oily acne-prone skin](https://lovi.care/skincare/sg/p/bayer/skinoren-cream-20/for/oily-acne-prone-skin): Average

## Key ingredients

Azelaic Acid, Benzoic Acid, Glycerin, Cetearyl Alcohol, Glyceryl Stearate

## What the research says

- Azelaic acid nanocrystal hydrogel 10% achieved a higher success rate and greater lesion reduction than azelaic acid cream 20% in patients with mild to moderate facial acne. ([Pharmaceutics, 2021](https://pubmed.ncbi.nlm.nih.gov/33923739/))
- Application of 15% azelaic acid gel significantly reduced post-inflammatory erythema and hyperpigmentation, decreased hemoglobin and melanin content, improved quality of life, and contributed to acne improvement in patients with mild to moderate acne compared to placebo. ([Dermatology and Therapy, 2024](https://pubmed.ncbi.nlm.nih.gov/38734843/))
- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Topical application of a dermocosmetic containing Myrtus communis extract and azelaic acid reduced acne relapses and helped maintain remission compared to a light moisturizing cream in adult females in the acne maintenance phase over 16 weeks. ([Journal of the European Academy of Dermatology and Venereology, 2023](https://pubmed.ncbi.nlm.nih.gov/36729399/))
- Topical administration of 20% azelaic acid cream and 5% tranexamic acid solution comparably improved acne-related postinflammatory hyperpigmentation in patients with acne vulgaris, while tranexamic acid demonstrated a significantly better safety profile at week 4. ([Journal of Research in Medical Sciences, 2023](https://pubmed.ncbi.nlm.nih.gov/37213446/))
- Azelaic acid 15% gel showed comparable efficacy to adapalene 0.1% gel in reducing lesions, severity, and Dermatology Life Quality Index in women with adult acne, with significantly lower dryness and scaling, and demonstrated superiority during maintenance compared to no further treatment. ([Journal of the European Academy of Dermatology and Venereology, 2015](https://pubmed.ncbi.nlm.nih.gov/25399481/))
- Trioxsalen bath PUVA therapy suppressed nonimmunologic immediate contact reactions to benzoic acid and methyl nicotinate in 12 dermatologic patients, with the suppressive effect intensifying during therapy. ([International Journal of Dermatology, 1989](https://pubmed.ncbi.nlm.nih.gov/2583908/))
- The emollient V0034CR significantly reduced TEWL compared to vehicle and vehicle plus glycerol, and significantly increased corneometry scores compared to vehicle and vehicle plus petrolatum in healthy volunteers with dry skin, demonstrating combined barrier function improvement from petrolatum and hydration improvement from glycerol. ([Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31532576/))
- Ten days of treatment with a cream containing 20% glycerin significantly increased skin hydration measured by corneometer values in 17 healthy volunteers compared to a placebo cream, but showed no influence on transepidermal water loss or skin sensitivity to an irritating surfactant. ([International Journal of Cosmetic Science, 2001](https://pubmed.ncbi.nlm.nih.gov/18498456/))
- Niacinamide/glycerin body moisturizers provided better rapid and prolonged improvement of cosmetic xerosis through functional improvement of stratum corneum barrier function compared to no treatment and conventional moisturizers in female subjects. ([Journal of Drugs in Dermatology, 2012](https://pubmed.ncbi.nlm.nih.gov/22206073/))

## What reviewers say

A significant number of reviewers note that patience is required due to a slow initial working period and common side effects like intense itching and dryness upon application.

- Liked: Clears active acne (mostly mentioned)
- Disliked: Itching and stinging (mostly mentioned)
- Liked: Fades dark spots (often mentioned)
- Disliked: Drying and flaking (often mentioned)
- Liked: Reduces redness (sometimes noted)
- Liked: Smooths skin texture (sometimes noted)
- Disliked: Initial purging phase (sometimes noted)
- Disliked: Slow onset (sometimes noted)

## How to apply

- Use your serum as part of your PM routine. Start using it 3 times a week and move to daily use if your skin likes it.
- Apply the serum after cleansing and toner, and right before your moisturizer.
- Gently press 2-3 drops of the serum into your skin and wait a minute ⏳for it to soak in.
- Apply the serum on clean and dry skin since your skin is not sensitive.
- Always do a patch test before using the serum for the first time, and avoid the eye area .
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### What makes Skinoren Cream 20% a great fit for combination skin?

Bayer Skinoren Cream 20% is a great fit because its high concentration of azelaic acid effectively reduces acne blemishes, controls oily shine, and improves skin texture. Glycerin also helps keep combination skin balanced by providing needed moisture without heavy oils, while the formula's gentle makeup is unlikely to cause irritation.
Sources: [Pharmaceutics, 2021](https://pubmed.ncbi.nlm.nih.gov/33923739/), [Dermatology and Therapy, 2024](https://pubmed.ncbi.nlm.nih.gov/38734843/)

### Which ingredients make this cream a good fit for combination skin?

Azelaic acid makes this cream a great fit for your combination skin because it helps clear acne breakouts, control oily shine, and smooth out your skin texture. Meanwhile, glycerin adds gentle moisture that keeps your skin balanced without clogging pores, and the formula has a very safe profile that is unlikely to cause irritation.
Sources: [Pharmaceutics, 2021](https://pubmed.ncbi.nlm.nih.gov/33923739/), [Dermatology and Therapy, 2024](https://pubmed.ncbi.nlm.nih.gov/38734843/)

### What does Azelaic Acid do for combination skin?

Azelaic acid helps combination skin by calming redness, clearing breakouts, and fading dark spots while keeping the skin smooth. It is unlikely to irritate dry areas while working on oily spots. Combination skin of this type needs a balanced routine with gentle exfoliants and soothing hydrators.
Sources: [Postepy Dermatologii I Alergologii, 2023](https://pubmed.ncbi.nlm.nih.gov/38282869/), [Journal of Drugs in Dermatology, 2015](https://pubmed.ncbi.nlm.nih.gov/26355614/)

### What does Benzoic Acid do for combination skin?

Benzoic acid helps keep formulas fresh and safe for daily use on combination skin. It is unlikely to cause irritation when used in typical cosmetic amounts, though it may occasionally trigger mild reactions in sensitive individuals.
Sources: [International Journal of Cosmetic Science, 2009](https://pubmed.ncbi.nlm.nih.gov/19627383/), [International Journal of Toxicology, 2001](https://pubmed.ncbi.nlm.nih.gov/11766131/)

### Where does this cream go in a skincare routine for combination skin?

This treatment goes in the evening routine after cleansing and before your moisturizer. Using it at night helps keep things simple and provides extra safety around sun exposure.

### Can I use this cream with retinol, and in what order?

This cream can be used alongside retinol by applying retinol at night and this treatment at a separate time or alternating nights to prevent irritation. Combining these ingredients is unlikely to cause issues because this product has a very safe formula with gentle ingredients, but you should introduce them slowly to keep your skin calm and smooth.

### How often should I use this cream?

You can use this treatment in your evening routine, applying it once a week at first and carefully increasing the frequency if your skin tolerates it well. It is very safe and is unlikely to cause irritation for your combination skin.

### Can this cream clog pores, cause breakouts or purging for combination skin?

Yes, this cream may cause an initial purging phase and breakouts when you first start using it. It is unlikely to cause long-term clogs, but reviewers often mention drying, flaking, itching, and stinging on combination skin.
Sources: [Pharmaceutics, 2021](https://pubmed.ncbi.nlm.nih.gov/33923739/)

### Is this cream fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol. Cetearyl alcohol is a fatty alcohol, which soften the skin.

## Alternatives for combination skin

- [Skin1004 Probio-Cica Intensive Ampoule](https://lovi.care/skincare/sg/p/skin1004/probio-cica-intensive-ampoule/for/combination-skin) — High fit — S$28.55 at Amazon
- [Neogen Dermalogy Real Vitamin C Serum](https://lovi.care/skincare/sg/p/neogen-dermalogy/real-vitamin-c-serum/for/combination-skin) — High fit — S$50.41 at Amazon
- [NEOGEN DERMALOGY REAL VITA C SERUM](https://lovi.care/skincare/sg/p/neogen-dermalogy/real-vita-c-serum/for/combination-skin) — High fit — S$50.41 at Amazon

## Pairs well with

- Cleanser: [Fresh Soy Face Cleanser](https://lovi.care/skincare/sg/p/fresh/soy-face-cleanser/for/combination-skin) — Superior fit — S$30.00 at Amazon
- Hydrating Toner: [Whamisa Organic Flowers Toner Deep Rich](https://lovi.care/skincare/sg/p/whamisa/organic-flowers-toner-deep-rich/for/combination-skin) — Superior fit — S$64.81 at Amazon
- SPF: [CeraVe AM Facial Moisturizing Lotion](https://lovi.care/skincare/sg/p/cerave/am-facial-moisturizing-lotion-spf-30/for/combination-skin) — Superior fit — S$28.72 at Amazon

## Where to buy

No store in Singapore has a checked price for this product, so the page shows none.

## Ingredients

Azelaic Acid, Glyceryl Stearate, Cetearyl Alcohol, Cetyl Palmitate, Water, Glycerin, Propylene Glycol, Cocoglycerides, Benzoic Acid, Glyceryl Stearate Malate, Cetearyl Nonanoate, Cetearyl Octanoate, Stearoyl Macrogolglycerides, Peg-30 Stearate
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/bayer/skinoren-cream-20/for/combination-skin
- United Kingdom: https://lovi.care/skincare/uk/p/bayer/skinoren-cream-20/for/combination-skin
- Ireland: https://lovi.care/skincare/ie/p/bayer/skinoren-cream-20/for/combination-skin
- Germany: https://lovi.care/skincare/de/p/bayer/skinoren-cream-20/for/combination-skin
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- Italy: https://lovi.care/skincare/it/p/bayer/skinoren-cream-20/for/combination-skin
- Netherlands: https://lovi.care/skincare/nl/p/bayer/skinoren-cream-20/for/combination-skin
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- Canada: https://lovi.care/skincare/ca/p/bayer/skinoren-cream-20/for/combination-skin
- Australia: https://lovi.care/skincare/au/p/bayer/skinoren-cream-20/for/combination-skin
- Singapore: https://lovi.care/skincare/sg/p/bayer/skinoren-cream-20/for/combination-skin (this page)
- Saudi Arabia: https://lovi.care/skincare/sa/p/bayer/skinoren-cream-20/for/combination-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/bayer/skinoren-cream-20/for/combination-skin