# Anua PDRN Hyaluronic Acid Capsule 100 Serum for combination skin

**Lovi Fit: Average fit for combination skin.**
Combination Skin Fit: High · Effectiveness: Average · Safety: High.

Page: https://lovi.care/skincare/sg/p/anua/pdrn-hyaluronic-acid-capsule-100-serum/for/combination-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Singapore.

Brand: [Anua](https://lovi.care/skincare/sg/brands/anua)
Category: [Moisturizers and moisturizing serums](https://lovi.care/skincare/sg/best/moisturizers)

This fit is calculated for the concerns frequently associated with combination skin: an oily T-zone, enlarged pores, and dry cheeks. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for combination skin; other moisturizers fit it better.

## Why this fit

- This serum offers excellent moisturizing benefits for your combination skin, with multiple forms of hyaluronic acid like Hydrolyzed Hyaluronic Acid and Sodium Hyaluronate Crosspolymer providing deep hydration and improving elasticity.
- Niacinamide is also present to help with seboregulation, though its impact on managing oily shine is supportive rather than primary.
- The formula is safe for your combination skin, as it lacks any harsh or prohibited ingredients that could cause irritation.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/sg/p/anua/pdrn-hyaluronic-acid-capsule-100-serum/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/sg/p/anua/pdrn-hyaluronic-acid-capsule-100-serum/for/dry-skin): Average
- [Combination skin](https://lovi.care/skincare/sg/p/anua/pdrn-hyaluronic-acid-capsule-100-serum/for/combination-skin): Average (this page)
- [Sensitive skin](https://lovi.care/skincare/sg/p/anua/pdrn-hyaluronic-acid-capsule-100-serum/for/sensitive-skin): Average
- [Acne-prone skin](https://lovi.care/skincare/sg/p/anua/pdrn-hyaluronic-acid-capsule-100-serum/for/acne-prone-skin): Average
- [Skin with dark spots](https://lovi.care/skincare/sg/p/anua/pdrn-hyaluronic-acid-capsule-100-serum/for/dark-spots): High
- [Mature skin](https://lovi.care/skincare/sg/p/anua/pdrn-hyaluronic-acid-capsule-100-serum/for/mature-skin): Average
- [Dry sensitive skin](https://lovi.care/skincare/sg/p/anua/pdrn-hyaluronic-acid-capsule-100-serum/for/dry-sensitive-skin): Average
- [Oily acne-prone skin](https://lovi.care/skincare/sg/p/anua/pdrn-hyaluronic-acid-capsule-100-serum/for/oily-acne-prone-skin): High

## Key ingredients

Hydrolyzed Hyaluronic Acid, Niacinamide, Glutathione

## What the research says

- Profhilo treatment led to significant improvements in superficial skin hydration and transepidermal water loss over time in Chinese females, while demonstrating good product tolerability. ([Aesthetic Plastic Surgery, 2026](https://pubmed.ncbi.nlm.nih.gov/40921777/))
- Polyelectrolyte nanocomplexes of quaternized cyclodextrin grafted chitosan and low molecular weight hyaluronic acid improved skin texture and elasticity by increasing skin hydration in clinical evaluation. ([Colloids and Surfaces. B, Biointerfaces, 2022](https://pubmed.ncbi.nlm.nih.gov/36279763/))
- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))
- Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33103316/))
- Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women. ([The Journal of Investigative Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/17882270/))
- Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging. ([Dermatologic Surgery, 2005](https://pubmed.ncbi.nlm.nih.gov/16029679/))
- Glutathione amino acid precursors effectively increase cellular glutathione levels, reducing oxidative stress, ATP depletion, and DNA damage in human keratinocytes, clinical subjects, and ex vivo skin compared to controls. ([Journal of the European Academy of Dermatology and Venereology, 2024](https://pubmed.ncbi.nlm.nih.gov/38189670/))
- Topical oxidized glutathione significantly decreases the skin melanin index and improves moisture content, smoothness, wrinkle formation, and elasticity compared to placebo in healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2014](https://pubmed.ncbi.nlm.nih.gov/25378941/))
- Topical glutathione improves hyperpigmentation, reduces ultraviolet-induced erythema and wrinkles, decreases transepidermal water loss, and enhances antioxidant capacity. ([The Journal of Clinical and Aesthetic Dermatology, 2025](https://pubmed.ncbi.nlm.nih.gov/41416233/))

## What reviewers say

Users consistently praise this serum for delivering the coveted "glass skin" look, offering deep hydration that plumps the skin without feeling heavy or greasy. While most find it excellent for barrier repair and instant glow, a minority feel it is simply a good hydrator rather than a "life-changing" treatment for the price.

- Liked: Deep hydration (mostly mentioned)
- Liked: Glass skin glow (often mentioned)
- Liked: Lightweight texture (often mentioned)
- Liked: Makeup compatibility (sometimes noted)
- Liked: Soothing & repair (sometimes noted)
- Disliked: Price vs volume (sometimes noted)
- Disliked: Breakouts (rarely noted)
- Disliked: Runny consistency (rarely noted)
- Disliked: Subtle results (rarely noted)
- Disliked: Texture issues (rarely noted)

## How to apply

- Use this moisturizer in your AM and PM routine every day to control shine. Always pair with SPF in the morning.
- Apply this moisturizer after your cleanser and toner, right before your morning SPF.
- Gently press a small amount of the moisturizer into your skin and avoid harsh rubbing. Let it ⏳absorb for a minute.
- Apply the moisturizer on slightly damp skin to help it lock in moisture better. This keeps your combination skin balanced.
- Avoid the eye area when applying the moisturizer. Do a patch test before your first use.
- Video: https://storage.pora.ai/2f72f5d69f07beeafc30237f829efbff.mp4

## Questions and answers

### How well does Anua PDRN Hyaluronic Acid Capsule 100 Serum work for combination skin?

This serum works decently for combination skin by delivering deep hydration with multiple forms of hyaluronic acid, though other options may fit it better. To truly excel on this skin type, a product needs a balanced blend of effective hydrators and oil-controlling ingredients like niacinamide and peptides that maintain moisture without adding excess shine.
Sources: [Aesthetic Plastic Surgery, 2026](https://pubmed.ncbi.nlm.nih.gov/40921777/)

### Which ingredients make this serum a good fit for combination skin?

Hydrolyzed Hyaluronic Acid and niacinamide make this serum a good fit by providing deep hydration and helping balance oil. To fit combination skin even better, a product like this needs ingredients like ceramides and peptides to keep moisture locked in and control shine effectively.
Sources: [Aesthetic Plastic Surgery, 2026](https://pubmed.ncbi.nlm.nih.gov/40921777/)

### What does Hydrolyzed Hyaluronic Acid do for combination skin?

Hydrolyzed hyaluronic acid helps keep combination skin hydrated and balanced without feeling heavy. It draws moisture into the skin while being lightweight enough to avoid making oily areas slick.
Sources: [Colloids and Surfaces. B, Biointerfaces, 2022](https://pubmed.ncbi.nlm.nih.gov/36279763/)

### What does Niacinamide do for combination skin?

Niacinamide helps balance oily areas by reducing excess shine and pore size while keeping dry patches hydrated and smooth. It also works to calm redness and even out skin tone, making it very suitable for combination skin.
Sources: [The British Journal of Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12100180/), [Antioxidants, 2021](https://pubmed.ncbi.nlm.nih.gov/34439563/)

### Where does this serum go in a skincare routine for combination skin?

This treatment goes in the evening routine after cleansing and before moisturizing, though some serums may also be used in the morning or twice a day. Combination skin of this type needs a balanced serum that provides deep hydration without feeling heavy, while offering gentle support for oily shine.

### Can I use this serum with retinol, and in what order?

You can use this serum with retinol by applying the serum first to give your combination skin deep hydration before adding your retinol. Using a hydrating serum underneath helps keep skin comfortable and is unlikely to cause irritation.
Sources: [Cutis, 2006](https://pubmed.ncbi.nlm.nih.gov/17121065/)

### How often should I use this serum?

This serum works well in your evening routine, but some treatments can also be used in the morning or twice a day. It is safe for your skin and helps provide deep hydration, though combination skin also needs strong oil control ingredients to manage oily shine.
Sources: [Health Science Reports, 2021](https://pubmed.ncbi.nlm.nih.gov/34141902/)

### Can this serum clog pores, cause breakouts or purging for combination skin?

This serum is unlikely to clog pores or cause breakouts on combination skin because its formula is safe and lacks harsh ingredients that typically cause irritation. To properly care for combination skin, this type of product needs hydrating ingredients like hyaluronic acid to keep dry areas soft and balancing ingredients like niacinamide to help manage oily shine.
Sources: [Aesthetic Plastic Surgery, 2026](https://pubmed.ncbi.nlm.nih.gov/40921777/)

### Can I use this serum around the eyes or on my body?

You can safely use this moisturizing treatment around the eyes and on the body because its formula is gentle and lacks harsh ingredients. For the thin skin around the eyes and on the body, a product of this type needs deep hydration from hyaluronic acid along with soothing ingredients to keep skin soft and smooth without irritation.
Sources: [Polymers, 2023](https://pubmed.ncbi.nlm.nih.gov/37896378/)

### Is this serum fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for combination skin

- [MEDI-PEEL Peptide 9 Volume White Cica All-in-one Essence](https://lovi.care/skincare/sg/p/medi-peel/peptide-9-volume-white-cica-all-in-one-essence/for/combination-skin) — High fit — S$41.73 at Amazon
- [COSRX Hydrium Triple Hyaluronic Moisture Ampoule](https://lovi.care/skincare/sg/p/cosrx/hydrium-triple-hyaluronic-moisture-ampoule/for/combination-skin) — High fit — S$21.96 at YesStyle
- [MISSHA Super Aqua Ultra Hyalron Ampoule](https://lovi.care/skincare/sg/p/missha/super-aqua-ultra-hyalron-ampoule/for/combination-skin) — Average fit — S$23.12 at YesStyle

## Pairs well with

- Cleanser: [Fresh Soy Face Cleanser](https://lovi.care/skincare/sg/p/fresh/soy-face-cleanser/for/combination-skin) — Superior fit — S$30.00 at Amazon
- Hydrating Toner: [Whamisa Organic Flowers Toner Deep Rich](https://lovi.care/skincare/sg/p/whamisa/organic-flowers-toner-deep-rich/for/combination-skin) — Superior fit — S$64.81 at Amazon
- SPF: [CeraVe AM Facial Moisturizing Lotion](https://lovi.care/skincare/sg/p/cerave/am-facial-moisturizing-lotion-spf-30/for/combination-skin) — Superior fit — S$28.72 at Amazon

## Where to buy

- YesStyle: S$30.50 (https://www.yesstyle.com/en/anua-pdrn-hyaluronic-acid-capsule-100-serum-30ml/info.html/pid.1132449410?curr=SGD&rco=SG)
Prices checked 17 Oct 2026.

## Ingredients

Water, Butylene Glycol, Propanediol, Glycerin, Hydrolyzed Hyaluronic Acid, 1,2-Hexanediol, Niacinamide, Glyceryl Oleate, Lauryl Glucoside, Myristyl Glucoside, Polyglyceryl-6 Laurate, Hydrogenated Lecithin, Glutathione, Hydrolyzed Collagen, Hyaluronic Acid, Coptis Japonica Root Extract, Adenosine, Sodium Dna, Hydrolyzed Sodium Hyaluronate, Hydroxypropyltrimonium Hyaluronate, Potassium Hyaluronate, Sodium Hyaluronate Crosspolymer, Sodium Acetylated Hyaluronate, Melia Azadirachta Leaf Extract, Melia Azadirachta Flower Extract, Coccinia Indica Fruit Extract, Solanum Melongena Fruit Extract, Ocimum Sanctum Leaf Extract, Citric Acid, Curcuma Longa Root Extract, Corallina Officinalis Extract, Sodium Citrate
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/anua/pdrn-hyaluronic-acid-capsule-100-serum/for/combination-skin
- United Kingdom: https://lovi.care/skincare/uk/p/anua/pdrn-hyaluronic-acid-capsule-100-serum/for/combination-skin
- Ireland: https://lovi.care/skincare/ie/p/anua/pdrn-hyaluronic-acid-capsule-100-serum/for/combination-skin
- Germany: https://lovi.care/skincare/de/p/anua/pdrn-hyaluronic-acid-capsule-100-serum/for/combination-skin
- France: https://lovi.care/skincare/fr/p/anua/pdrn-hyaluronic-acid-capsule-100-serum/for/combination-skin
- Italy: https://lovi.care/skincare/it/p/anua/pdrn-hyaluronic-acid-capsule-100-serum/for/combination-skin
- Netherlands: https://lovi.care/skincare/nl/p/anua/pdrn-hyaluronic-acid-capsule-100-serum/for/combination-skin
- Spain: https://lovi.care/skincare/es/p/anua/pdrn-hyaluronic-acid-capsule-100-serum/for/combination-skin
- Canada: https://lovi.care/skincare/ca/p/anua/pdrn-hyaluronic-acid-capsule-100-serum/for/combination-skin
- Australia: https://lovi.care/skincare/au/p/anua/pdrn-hyaluronic-acid-capsule-100-serum/for/combination-skin
- Singapore: https://lovi.care/skincare/sg/p/anua/pdrn-hyaluronic-acid-capsule-100-serum/for/combination-skin (this page)
- Saudi Arabia: https://lovi.care/skincare/sa/p/anua/pdrn-hyaluronic-acid-capsule-100-serum/for/combination-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/anua/pdrn-hyaluronic-acid-capsule-100-serum/for/combination-skin