# Tretinoin

Page: https://lovi.care/skincare/sg/ingredients/tretinoin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Singapore.

Daily application of topical tretinoin steadily builds deep [collagen](https://lovi.care/skincare/sg/ingredients/collagen), clearly smooths fine lines and dark spots, and calms troublesome breakouts by clearing pores and reducing redness. This refined active ingredient suits both dry skin and oily skin particularly well, and it is easily found in lightweight [serums](https://lovi.care/skincare/sg/ingredients/serum). To keep your skin comfortable, simply apply your tretinoin at a separate time from [glycolic acid](https://lovi.care/skincare/sg/ingredients/glycolic-acid), [benzoyl peroxide](https://lovi.care/skincare/sg/ingredients/benzoyl-peroxide), and [vitamin C](https://lovi.care/skincare/sg/ingredients/vitamin-c).

[The New England Journal of Medicine, 1993](https://pubmed.ncbi.nlm.nih.gov/8336752/) [Clinical, Cosmetic and Investigational Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/32210603/) [Archives of Dermatological Research, 2022](https://pubmed.ncbi.nlm.nih.gov/34146120/)

This page shows tretinoin products with a Lovi page. For every product, and a routine built for your skin, use the Lovi app.

### Popular tretinoin products

- [Retin-A Cream](https://lovi.care/skincare/sg/p/retin-a/cream/for/oily-skin) — High fit
- [Tri-Luma Cream](https://lovi.care/skincare/sg/p/tri-luma/cream/for/dark-spots) — Average fit
- [Musely The Spot Cream](https://lovi.care/skincare/sg/p/musely/the-spot-cream/for/mature-skin) — High fit
- [Obagi Tretinoin Cream 0.05%](https://lovi.care/skincare/sg/p/obagi/tretinoin-cream-0-05/for/oily-skin) — High fit
- [Taro Tretinoin Cream](https://lovi.care/skincare/sg/p/taro/tretinoin-cream/for/combination-skin) — High fit
- [Mylan Tretinoin](https://lovi.care/skincare/sg/p/mylan/tretinoin/for/acne-prone-skin) — Average fit
- [Curology Formula](https://lovi.care/skincare/sg/p/curology/formula/for/oily-skin) — High fit
- [Menarini A-Ret Gel](https://lovi.care/skincare/sg/p/menarini/a-ret-gel/for/oily-skin) — High fit

### Tretinoin [serums](https://lovi.care/skincare/sg/ingredients/serum)

- [Retin-A Cream](https://lovi.care/skincare/sg/p/retin-a/cream/for/oily-skin) — High fit
- [Tri-Luma Cream](https://lovi.care/skincare/sg/p/tri-luma/cream/for/dark-spots) — Average fit
- [Musely The Spot Cream](https://lovi.care/skincare/sg/p/musely/the-spot-cream/for/mature-skin) — High fit
- [Obagi Tretinoin Cream 0.05%](https://lovi.care/skincare/sg/p/obagi/tretinoin-cream-0-05/for/oily-skin) — High fit
- [Taro Tretinoin Cream](https://lovi.care/skincare/sg/p/taro/tretinoin-cream/for/combination-skin) — High fit
- [Mylan Tretinoin](https://lovi.care/skincare/sg/p/mylan/tretinoin/for/acne-prone-skin) — Average fit
- [Curology Formula](https://lovi.care/skincare/sg/p/curology/formula/for/oily-skin) — High fit
- [Menarini A-Ret Gel](https://lovi.care/skincare/sg/p/menarini/a-ret-gel/for/oily-skin) — High fit

## What reviewers say about popular tretinoin products

The highlight reviewers mention most for each popular tretinoin product on Lovi.

- Retin-A Cream Initial breakouts ★4.0 · 200+ reviews Smooths skin Dryness and peeling “I had full blown acne, everywhere” [What people say about Cream](https://lovi.care/skincare/sg/p/retin-a/cream/for/oily-skin)
- Tri-Luma Cream Rapid Melasma Clearance ★3.8 · 200+ reviews Effective on Stubborn Spots High Cost “cleared my brown spots” [What people say about Cream](https://lovi.care/skincare/sg/p/tri-luma/cream/for/dark-spots)
- Musely The Spot Cream Boosts confidence ★4.2 · 1.5k+ reviews Irritation and peeling Fast results “No more concealer” [What people say about The Spot Cream](https://lovi.care/skincare/sg/p/musely/the-spot-cream/for/mature-skin)
- Obagi Tretinoin Cream 0.05% Transforms skin ★4.9 · 100+ reviews Intense peeling Reduces aging “smooth as a baby” [What people say about Tretinoin Cream 0.05%](https://lovi.care/skincare/sg/p/obagi/tretinoin-cream-0-05/for/oily-skin)
- Taro Tretinoin Cream Reduces fine lines ★4.3 · 800+ reviews Initial skin peeling Smooth, spreadable texture “At 55, my skin looks better than it did in my 30s.” [What people say about Tretinoin Cream](https://lovi.care/skincare/sg/p/taro/tretinoin-cream/for/combination-skin)
- Mylan Tretinoin Gel pills ★3.9 · 800+ reviews Severe dryness/peeling Strong alcohol smell “consistency of chunky super glue” [What people say about Tretinoin](https://lovi.care/skincare/sg/p/mylan/tretinoin/for/acne-prone-skin)

### Tretinoin for dry skin

- [Taro Tretinoin Cream](https://lovi.care/skincare/sg/p/taro/tretinoin-cream/for/dry-skin) — Low fit
- [Musely The Spot Cream](https://lovi.care/skincare/sg/p/musely/the-spot-cream/for/dry-skin) — Low fit
- [Obagi Tretinoin Cream 0.05%](https://lovi.care/skincare/sg/p/obagi/tretinoin-cream-0-05/for/dry-skin) — Low fit
- [Curology Formula](https://lovi.care/skincare/sg/p/curology/formula/for/dry-skin) — Low fit
- [Tri-Luma Cream](https://lovi.care/skincare/sg/p/tri-luma/cream/for/dry-skin) — Caution fit
- [Retin-A Cream](https://lovi.care/skincare/sg/p/retin-a/cream/for/dry-skin) — Caution fit
- [Menarini A-Ret Gel](https://lovi.care/skincare/sg/p/menarini/a-ret-gel/for/dry-skin) — Caution fit
- [Mylan Tretinoin](https://lovi.care/skincare/sg/p/mylan/tretinoin/for/dry-skin) — Caution fit

### Tretinoin for oily skin

- [Curology Formula](https://lovi.care/skincare/sg/p/curology/formula/for/oily-skin) — High fit
- [Obagi Tretinoin Cream 0.05%](https://lovi.care/skincare/sg/p/obagi/tretinoin-cream-0-05/for/oily-skin) — High fit
- [Retin-A Cream](https://lovi.care/skincare/sg/p/retin-a/cream/for/oily-skin) — High fit
- [Menarini A-Ret Gel](https://lovi.care/skincare/sg/p/menarini/a-ret-gel/for/oily-skin) — High fit
- [Musely The Spot Cream](https://lovi.care/skincare/sg/p/musely/the-spot-cream/for/oily-skin) — Average fit
- [Taro Tretinoin Cream](https://lovi.care/skincare/sg/p/taro/tretinoin-cream/for/oily-skin) — Average fit
- [Tri-Luma Cream](https://lovi.care/skincare/sg/p/tri-luma/cream/for/oily-skin) — Low fit
- [Mylan Tretinoin](https://lovi.care/skincare/sg/p/mylan/tretinoin/for/oily-skin) — Low fit

### Tretinoin for combination skin

- [Taro Tretinoin Cream](https://lovi.care/skincare/sg/p/taro/tretinoin-cream/for/combination-skin) — High fit
- [Obagi Tretinoin Cream 0.05%](https://lovi.care/skincare/sg/p/obagi/tretinoin-cream-0-05/for/combination-skin) — High fit
- [Retin-A Cream](https://lovi.care/skincare/sg/p/retin-a/cream/for/combination-skin) — High fit
- [Curology Formula](https://lovi.care/skincare/sg/p/curology/formula/for/combination-skin) — Average fit
- [Menarini A-Ret Gel](https://lovi.care/skincare/sg/p/menarini/a-ret-gel/for/combination-skin) — Average fit
- [Musely The Spot Cream](https://lovi.care/skincare/sg/p/musely/the-spot-cream/for/combination-skin) — Average fit
- [Tri-Luma Cream](https://lovi.care/skincare/sg/p/tri-luma/cream/for/combination-skin) — Low fit
- [Mylan Tretinoin](https://lovi.care/skincare/sg/p/mylan/tretinoin/for/combination-skin) — Low fit

### Tretinoin for sensitive skin

- [Musely The Spot Cream](https://lovi.care/skincare/sg/p/musely/the-spot-cream/for/sensitive-skin) — Average fit
- [Tri-Luma Cream](https://lovi.care/skincare/sg/p/tri-luma/cream/for/sensitive-skin) — Average fit
- [Curology Formula](https://lovi.care/skincare/sg/p/curology/formula/for/sensitive-skin) — Low fit
- [Taro Tretinoin Cream](https://lovi.care/skincare/sg/p/taro/tretinoin-cream/for/sensitive-skin) — Low fit
- [Retin-A Cream](https://lovi.care/skincare/sg/p/retin-a/cream/for/sensitive-skin) — Low fit
- [Obagi Tretinoin Cream 0.05%](https://lovi.care/skincare/sg/p/obagi/tretinoin-cream-0-05/for/sensitive-skin) — Low fit
- [Menarini A-Ret Gel](https://lovi.care/skincare/sg/p/menarini/a-ret-gel/for/sensitive-skin) — Low fit
- [Mylan Tretinoin](https://lovi.care/skincare/sg/p/mylan/tretinoin/for/sensitive-skin) — Caution fit

### Tretinoin for acne-prone skin

- [Obagi Tretinoin Cream 0.05%](https://lovi.care/skincare/sg/p/obagi/tretinoin-cream-0-05/for/acne-prone-skin) — High fit
- [Taro Tretinoin Cream](https://lovi.care/skincare/sg/p/taro/tretinoin-cream/for/acne-prone-skin) — High fit
- [Musely The Spot Cream](https://lovi.care/skincare/sg/p/musely/the-spot-cream/for/acne-prone-skin) — High fit
- [Curology Formula](https://lovi.care/skincare/sg/p/curology/formula/for/acne-prone-skin) — Average fit
- [Menarini A-Ret Gel](https://lovi.care/skincare/sg/p/menarini/a-ret-gel/for/acne-prone-skin) — Average fit
- [Mylan Tretinoin](https://lovi.care/skincare/sg/p/mylan/tretinoin/for/acne-prone-skin) — Average fit
- [Retin-A Cream](https://lovi.care/skincare/sg/p/retin-a/cream/for/acne-prone-skin) — Average fit
- [Tri-Luma Cream](https://lovi.care/skincare/sg/p/tri-luma/cream/for/acne-prone-skin) — Low fit

### Tretinoin for mature skin

- [Musely The Spot Cream](https://lovi.care/skincare/sg/p/musely/the-spot-cream/for/mature-skin) — High fit
- [Retin-A Cream](https://lovi.care/skincare/sg/p/retin-a/cream/for/mature-skin) — Average fit
- [Curology Formula](https://lovi.care/skincare/sg/p/curology/formula/for/mature-skin) — Average fit
- [Obagi Tretinoin Cream 0.05%](https://lovi.care/skincare/sg/p/obagi/tretinoin-cream-0-05/for/mature-skin) — Average fit
- [Tri-Luma Cream](https://lovi.care/skincare/sg/p/tri-luma/cream/for/mature-skin) — Average fit
- [Taro Tretinoin Cream](https://lovi.care/skincare/sg/p/taro/tretinoin-cream/for/mature-skin) — Average fit
- [Menarini A-Ret Gel](https://lovi.care/skincare/sg/p/menarini/a-ret-gel/for/mature-skin) — Low fit
- [Mylan Tretinoin](https://lovi.care/skincare/sg/p/mylan/tretinoin/for/mature-skin) — Caution fit

## What to combine tretinoin with

Ingredient Together How to use them

[Niacinamide](https://lovi.care/skincare/sg/ingredients/niacinamide) Depends Use them at different times of day, applying [niacinamide](https://lovi.care/skincare/sg/ingredients/niacinamide) in the morning and tretinoin at night, to keep your skin calm. [Tretinoin and niacinamide](https://lovi.care/skincare/sg/ingredients/niacinamide-and-tretinoin) [Glycolic acid](https://lovi.care/skincare/sg/ingredients/glycolic-acid) Keep apart Use them on alternate nights because they are both strong and should not go on together. [Tretinoin and glycolic acid](https://lovi.care/skincare/sg/ingredients/glycolic-acid-and-tretinoin) [Benzoyl peroxide](https://lovi.care/skincare/sg/ingredients/benzoyl-peroxide) Keep apart Use them at different times of day, applying [benzoyl peroxide](https://lovi.care/skincare/sg/ingredients/benzoyl-peroxide) in the morning and tretinoin at night, because they cancel each other out. [Tretinoin and benzoyl peroxide](https://lovi.care/skincare/sg/ingredients/benzoyl-peroxide-and-tretinoin) [Vitamin C](https://lovi.care/skincare/sg/ingredients/vitamin-c) Keep apart Use [vitamin C](https://lovi.care/skincare/sg/ingredients/vitamin-c) in the morning and tretinoin at night to prevent irritation. [Tretinoin and vitamin C](https://lovi.care/skincare/sg/ingredients/vitamin-c-and-tretinoin) [AHA blend glycolic and citric acids](https://lovi.care/skincare/sg/ingredients/aha-blend-glycolic-and-citric-acids) Keep apart Use them on alternate nights, applying the acid blend on one evening and the tretinoin on the next, to prevent severe skin irritation. [Tretinoin and aha blend glycolic and citric acids](https://lovi.care/skincare/sg/ingredients/aha-blend-glycolic-and-citric-acids-and-tretinoin) [Salicylic acid](https://lovi.care/skincare/sg/ingredients/salicylic-acid) Keep apart Use [salicylic acid](https://lovi.care/skincare/sg/ingredients/salicylic-acid) and tretinoin on alternate nights to prevent skin irritation. [Tretinoin and salicylic acid](https://lovi.care/skincare/sg/ingredients/salicylic-acid-and-tretinoin) [Bio-placenta peptides](https://lovi.care/skincare/sg/ingredients/bio-placenta-peptides) Keep apart Use them at different times of day, applying your peptides in the morning and tretinoin at night to prevent irritation. [Tretinoin and bio-placenta peptides](https://lovi.care/skincare/sg/ingredients/tretinoin-and-bio-placenta-peptides) [Hexapeptide](https://lovi.care/skincare/sg/ingredients/hexapeptide) Keep apart Use them at different times of day by applying your peptide product in the morning and tretinoin at night to prevent skin irritation. [Tretinoin and hexapeptide](https://lovi.care/skincare/sg/ingredients/tretinoin-and-hexapeptide) [Lactic acid](https://lovi.care/skincare/sg/ingredients/lactic-acid) Keep apart Use them on alternate nights because combining them causes irritation. [Tretinoin and lactic acid](https://lovi.care/skincare/sg/ingredients/tretinoin-and-lactic-acid) [Acetyl hexapeptide-3](https://lovi.care/skincare/sg/ingredients/acetyl-hexapeptide-3) Keep apart Use them at different times of day by applying [acetyl hexapeptide-3](https://lovi.care/skincare/sg/ingredients/acetyl-hexapeptide-3) in the morning and tretinoin at night to prevent irritation. [Tretinoin and acetyl hexapeptide-3](https://lovi.care/skincare/sg/ingredients/tretinoin-and-acetyl-hexapeptide-3) [Mandelic acid](https://lovi.care/skincare/sg/ingredients/mandelic-acid) Keep apart Use them on alternate nights because combining them too often can cause skin irritation and redness. [Tretinoin and mandelic acid](https://lovi.care/skincare/sg/ingredients/tretinoin-and-mandelic-acid) [Collagen peptide](https://lovi.care/skincare/sg/ingredients/collagen-peptide) Keep apart Use them at different times of day, applying [collagen peptides](https://lovi.care/skincare/sg/ingredients/collagen-peptide) in the morning and tretinoin at night. [Tretinoin and collagen peptide](https://lovi.care/skincare/sg/ingredients/tretinoin-and-collagen-peptide) [Copper peptide](https://lovi.care/skincare/sg/ingredients/copper-peptide) Keep apart Use them at different times of day, applying the peptide product in the morning and tretinoin at night, to prevent skin irritation. [Tretinoin and copper peptide](https://lovi.care/skincare/sg/ingredients/tretinoin-and-copper-peptide) [Citric acid](https://lovi.care/skincare/sg/ingredients/citric-acid) Keep apart Use them on alternate nights because they both increase cell turnover and can cause irritation when layered together. [Tretinoin and citric acid](https://lovi.care/skincare/sg/ingredients/tretinoin-and-citric-acid) [Hexapeptide-9](https://lovi.care/skincare/sg/ingredients/hexapeptide-9) Keep apart Use them at different times of day, applying [hexapeptide-9](https://lovi.care/skincare/sg/ingredients/hexapeptide-9) in the morning and tretinoin at night, because combining them in the same routine can cause irritation. [Tretinoin and hexapeptide-9](https://lovi.care/skincare/sg/ingredients/tretinoin-and-hexapeptide-9) [Peptide-rich plasma](https://lovi.care/skincare/sg/ingredients/peptide-rich-plasma) Keep apart Use them at different times of day by applying peptides in the morning and tretinoin at night to prevent irritation. [Tretinoin and peptide-rich plasma](https://lovi.care/skincare/sg/ingredients/tretinoin-and-peptide-rich-plasma) [Triple peptide blend](https://lovi.care/skincare/sg/ingredients/triple-peptide-blend) Keep apart Use them at different times of day by applying your peptide product in the morning and tretinoin at night to prevent skin irritation. [Tretinoin and triple peptide blend](https://lovi.care/skincare/sg/ingredients/tretinoin-and-triple-peptide-blend) [Palmitoyl pentapeptide-4](https://lovi.care/skincare/sg/ingredients/palmitoyl-pentapeptide-4) Keep apart Use them at different times of day by applying [palmitoyl pentapeptide-4](https://lovi.care/skincare/sg/ingredients/palmitoyl-pentapeptide-4) in the morning and tretinoin at night to prevent skin irritation. [Tretinoin and palmitoyl pentapeptide-4](https://lovi.care/skincare/sg/ingredients/tretinoin-and-palmitoyl-pentapeptide-4) [Palmitoyl tripeptide-1](https://lovi.care/skincare/sg/ingredients/palmitoyl-tripeptide-1) Keep apart Use them at different times of day by applying your peptide product in the morning and your tretinoin at night. [Tretinoin and palmitoyl tripeptide-1](https://lovi.care/skincare/sg/ingredients/tretinoin-and-palmitoyl-tripeptide-1)

From the ingredient rules behind the "Works well with" and "Don't mix with" notes on every product in the Lovi app.

## Questions and answers

### What does tretinoin do for the skin?

Tretinoin helps improve the clinical appearance of photoaging in terms of wrinkling, mottled hyperpigmentation, sallowness, and lentigines. Daily application may also produce an increase in [collagen](https://lovi.care/skincare/sg/ingredients/collagen) I formation in photodamaged skin.

[International Journal of Women's Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/35620028/) [The New England Journal of Medicine, 1993](https://pubmed.ncbi.nlm.nih.gov/8336752/)

### How do you use tretinoin?

Tretinoin is applied at night to help improve the clinical appearance of photoaging and reduce acne lesions. Daily application helps restore collagen formation in photodamaged human skin over time.

[International Journal of Women's Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/35620028/) [Archives of Dermatological Research, 2022](https://pubmed.ncbi.nlm.nih.gov/34146120/)

### Should you use tretinoin in the morning or at night?

You should use tretinoin at night to help prevent irritation and ensure the best results. Applying it at night also allows it to work effectively alongside morning partner ingredients like [vitamin C](https://lovi.care/skincare/sg/ingredients/vitamin-c) or peptides without causing skin issues.

[International Journal of Women's Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/35620028/)

### Can you use tretinoin every day?

Yes, you can use tretinoin every day for photoaging, as daily application helps increase collagen formation. Topical tretinoin improves the clinical appearance of wrinkles and mottled hyperpigmentation while remaining safe and well tolerated.

[The New England Journal of Medicine, 1993](https://pubmed.ncbi.nlm.nih.gov/8336752/) [International Journal of Women's Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/35620028/)

### Does tretinoin cause purging or irritation?

Yes, tretinoin may cause skin irritation and redness. It helps improve the clinical appearance of photoaging and is safe and well tolerated.

[Clinical, Cosmetic and Investigational Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/32210603/) [International Journal of Women's Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/35620028/)

### Which skin types is tretinoin best for?

Tretinoin is best for oily, combination, acne-prone, and mature skin types. For oily acne-prone skin, Lovi gives High fit ratings to products like Retin-A Cream, Curology Formula, and Menarini A-Ret Gel.

### Can you use tretinoin with glycolic acid?

Keep them apart by using [glycolic acid](https://lovi.care/skincare/sg/ingredients/glycolic-acid) and tretinoin on alternate nights because they are both strong and should not go on together.

## Research on tretinoin

- [Restoration of collagen formation in photodamaged human skin by tretinoin (retinoic acid)](https://pubmed.ncbi.nlm.nih.gov/8336752/) Tretinoin · The New England Journal of Medicine, 1993
- [Clinical Assessment of New Topical Cream Containing Two Essential Oils Combined with Tretinoin in the Treatment of Acne](https://pubmed.ncbi.nlm.nih.gov/32210603/) Tretinoin · Clinical, Cosmetic and Investigational Dermatology, 2020
- [Efficacy assessments of tretinoin-loaded nano lipid carriers in acne vulgaris: a double blind, split-face randomized clinical study](https://pubmed.ncbi.nlm.nih.gov/34146120/) Tretinoin · Archives of Dermatological Research, 2022
- [Topical tretinoin for treating photoaging: A systematic review of randomized controlled trials](https://pubmed.ncbi.nlm.nih.gov/35620028/) Tretinoin · International Journal of Women's Dermatology, 2022

## Combining tretinoin

- Keep them apart: [Tretinoin and acetyl hexapeptide-3](https://lovi.care/skincare/sg/ingredients/tretinoin-and-acetyl-hexapeptide-3)
- Keep them apart: [Tretinoin and bio-placenta peptides](https://lovi.care/skincare/sg/ingredients/tretinoin-and-bio-placenta-peptides)
- Keep them apart: [Tretinoin and collagen peptide](https://lovi.care/skincare/sg/ingredients/tretinoin-and-collagen-peptide)
- Keep them apart: [Tretinoin and copper peptide](https://lovi.care/skincare/sg/ingredients/tretinoin-and-copper-peptide)
- Keep them apart: [Tretinoin and hexapeptide](https://lovi.care/skincare/sg/ingredients/tretinoin-and-hexapeptide)
- Keep them apart: [Tretinoin and hexapeptide-9](https://lovi.care/skincare/sg/ingredients/tretinoin-and-hexapeptide-9)
- Keep them apart: [Tretinoin and palmitoyl pentapeptide-4](https://lovi.care/skincare/sg/ingredients/tretinoin-and-palmitoyl-pentapeptide-4)
- Keep them apart: [Tretinoin and palmitoyl tripeptide-1](https://lovi.care/skincare/sg/ingredients/tretinoin-and-palmitoyl-tripeptide-1)
- Keep them apart: [Tretinoin and peptide-rich plasma](https://lovi.care/skincare/sg/ingredients/tretinoin-and-peptide-rich-plasma)
- Keep them apart: [Tretinoin and triple peptide blend](https://lovi.care/skincare/sg/ingredients/tretinoin-and-triple-peptide-blend)
- Depends on the strength: [Niacinamide and tretinoin](https://lovi.care/skincare/sg/ingredients/niacinamide-and-tretinoin)
- Keep them apart: [AHA blend glycolic and citric acids and tretinoin](https://lovi.care/skincare/sg/ingredients/aha-blend-glycolic-and-citric-acids-and-tretinoin)
- Keep them apart: [Tretinoin and citric acid](https://lovi.care/skincare/sg/ingredients/tretinoin-and-citric-acid)
- Keep them apart: [Glycolic acid and tretinoin](https://lovi.care/skincare/sg/ingredients/glycolic-acid-and-tretinoin)
- Keep them apart: [Tretinoin and lactic acid](https://lovi.care/skincare/sg/ingredients/tretinoin-and-lactic-acid)
- Keep them apart: [Tretinoin and mandelic acid](https://lovi.care/skincare/sg/ingredients/tretinoin-and-mandelic-acid)
- Keep them apart: [Salicylic acid and tretinoin](https://lovi.care/skincare/sg/ingredients/salicylic-acid-and-tretinoin)
- Keep them apart: [Vitamin C and tretinoin](https://lovi.care/skincare/sg/ingredients/vitamin-c-and-tretinoin)
- Keep them apart: [Benzoyl peroxide and tretinoin](https://lovi.care/skincare/sg/ingredients/benzoyl-peroxide-and-tretinoin)

## Brands with tretinoin

- Skincare: [Menarini](https://lovi.care/skincare/sg/brands/menarini)
- Skincare: [Taro](https://lovi.care/skincare/sg/brands/taro)
- American skincare: [Retin-A](https://lovi.care/skincare/sg/brands/retin-a)
- American skincare: [Tri-Luma](https://lovi.care/skincare/sg/brands/tri-luma)
- American skincare: [Musely](https://lovi.care/skincare/sg/brands/musely)
- American skincare: [Obagi](https://lovi.care/skincare/sg/brands/obagi)
- American skincare: [Curology](https://lovi.care/skincare/sg/brands/curology)
- American skincare: [Mylan](https://lovi.care/skincare/sg/brands/mylan)

## Related ingredients

- [Glycolic acid](https://lovi.care/skincare/sg/ingredients/glycolic-acid)
- [Benzoyl peroxide](https://lovi.care/skincare/sg/ingredients/benzoyl-peroxide)
- [Vitamin C](https://lovi.care/skincare/sg/ingredients/vitamin-c)
- [AHA blend glycolic and citric acids](https://lovi.care/skincare/sg/ingredients/aha-blend-glycolic-and-citric-acids)
- [Niacinamide](https://lovi.care/skincare/sg/ingredients/niacinamide)
- [Salicylic acid](https://lovi.care/skincare/sg/ingredients/salicylic-acid)
- [Bio-placenta peptides](https://lovi.care/skincare/sg/ingredients/bio-placenta-peptides)
- [Hexapeptide](https://lovi.care/skincare/sg/ingredients/hexapeptide)
- [Lactic acid](https://lovi.care/skincare/sg/ingredients/lactic-acid)
- [Acetyl hexapeptide-3](https://lovi.care/skincare/sg/ingredients/acetyl-hexapeptide-3)
- [Mandelic acid](https://lovi.care/skincare/sg/ingredients/mandelic-acid)
- [Collagen peptide](https://lovi.care/skincare/sg/ingredients/collagen-peptide)
- [Copper peptide](https://lovi.care/skincare/sg/ingredients/copper-peptide)
- [Citric acid](https://lovi.care/skincare/sg/ingredients/citric-acid)
- [Hexapeptide-9](https://lovi.care/skincare/sg/ingredients/hexapeptide-9)
- [Peptide-rich plasma](https://lovi.care/skincare/sg/ingredients/peptide-rich-plasma)
- [Triple peptide blend](https://lovi.care/skincare/sg/ingredients/triple-peptide-blend)
- [Palmitoyl pentapeptide-4](https://lovi.care/skincare/sg/ingredients/palmitoyl-pentapeptide-4)
- [Palmitoyl tripeptide-1](https://lovi.care/skincare/sg/ingredients/palmitoyl-tripeptide-1)

## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi checks every ingredient with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this ingredient guide: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/ingredients/tretinoin
- United Kingdom: https://lovi.care/skincare/uk/ingredients/tretinoin
- Ireland: https://lovi.care/skincare/ie/ingredients/tretinoin
- Germany: https://lovi.care/skincare/de/ingredients/tretinoin
- France: https://lovi.care/skincare/fr/ingredients/tretinoin
- Italy: https://lovi.care/skincare/it/ingredients/tretinoin
- Netherlands: https://lovi.care/skincare/nl/ingredients/tretinoin
- Spain: https://lovi.care/skincare/es/ingredients/tretinoin
- Canada: https://lovi.care/skincare/ca/ingredients/tretinoin
- Australia: https://lovi.care/skincare/au/ingredients/tretinoin
- Singapore: https://lovi.care/skincare/sg/ingredients/tretinoin (this page)
- Saudi Arabia: https://lovi.care/skincare/sa/ingredients/tretinoin
- United Arab Emirates: https://lovi.care/skincare/ae/ingredients/tretinoin
