# Salicylic acid and gluconolactone

Page: https://lovi.care/skincare/sg/ingredients/salicylic-acid-and-gluconolactone

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Singapore.

Work well together

Use them together, applying [salicylic acid](https://lovi.care/skincare/sg/ingredients/salicylic-acid) first and [gluconolactone](https://lovi.care/skincare/sg/ingredients/gluconolactone) second, because they make a gentle and hydrating exfoliating team. Salicylic acid clears out pores while gluconolactone attracts moisture and soothes the skin to prevent irritation. You can try a lower strength if your skin feels too sensitive, or wait a few minutes between applying them.

[The use of polyhydroxy acids (PHAs) in photoaged skin](https://pubmed.ncbi.nlm.nih.gov/15002656/) [A polyhydroxy acid skin care regimen provides antiaging effects comparable to an alpha-hydroxyacid regimen](https://pubmed.ncbi.nlm.nih.gov/15002657/)

- [All about salicylic acid](https://lovi.care/skincare/sg/ingredients/salicylic-acid)
- [All about gluconolactone](https://lovi.care/skincare/sg/ingredients/gluconolactone)

### [Salicylic acid](https://lovi.care/skincare/sg/ingredients/salicylic-acid) products

- [Paula's Choice Skin Perfecting 2% BHA Liquid Exfoliant](https://lovi.care/skincare/sg/p/paula-s-choice/skin-perfecting-2-bha-liquid-exfoliant/for/oily-skin) — Superior fit
- [Medicube Zero Pore Pad](https://lovi.care/skincare/sg/p/medicube/zero-pore-pad/for/oily-skin) — Superior fit — [S$36.48 at Amazon](https://www.amazon.sg/dp/B0CV7RX6ML?tag=lovi-care-web-product0e-22&linkCode=osi&th=1&psc=1)
- [CeraVe Renewing SA Cleanser](https://lovi.care/skincare/sg/p/cerave/renewing-sa-cleanser/for/oily-acne-prone-skin) — High fit — [S$28.59 at Amazon](https://www.amazon.sg/dp/B08CQ9T6KN?tag=lovi-care-web-product0e-22&linkCode=osi&th=1&psc=1)
- [Dermalogica Daily Microfoliant](https://lovi.care/skincare/sg/p/dermalogica/daily-microfoliant/for/oily-skin) — Superior fit
- [The Ordinary Salicylic Acid 2% Solution](https://lovi.care/skincare/sg/p/the-ordinary/salicylic-acid-2-solution/for/dry-skin) — Average fit
- [Mario Badescu Drying Lotion](https://lovi.care/skincare/sg/p/mario-badescu/drying-lotion/for/oily-skin) — High fit
- [La Roche-Posay Effaclar Medicated Gel Cleanser](https://lovi.care/skincare/sg/p/la-roche-posay/effaclar-medicated-gel-cleanser/for/acne-prone-skin) — High fit
- [The Ordinary AHA 30% + BHA 2% Peeling Solution](https://lovi.care/skincare/sg/p/the-ordinary/aha-30-bha-2-peeling-solution/for/oily-acne-prone-skin) — Superior fit — [S$23.22 at YesStyle](https://www.yesstyle.com/en/the-ordinary-aha-30-bha-2-peeling-solution-30ml/info.html/pid.1112381312?curr=SGD&rco=SG)
- [Paula's Choice 10% Azelaic Acid Booster](https://lovi.care/skincare/sg/p/paula-s-choice/10-azelaic-acid-booster/for/acne-prone-skin) — High fit
- [CeraVe SA Lotion for Rough & Bumpy Skin](https://lovi.care/skincare/sg/p/cerave/sa-lotion-for-rough-and-bumpy-skin/for/oily-skin) — Average fit — [S$31.36 at Amazon](https://www.amazon.sg/dp/B0071XPQQ2?tag=lovi-care-web-product0e-22&linkCode=osi&th=1&psc=1)
- [COSRX BHA Blackhead Power Liquid](https://lovi.care/skincare/sg/p/cosrx/bha-blackhead-power-liquid/for/oily-acne-prone-skin) — Superior fit — [S$17.75 at YesStyle](https://www.yesstyle.com/en/cosrx-bha-blackhead-power-liquid/info.html/pid.1052684693?curr=SGD&rco=SG)
- [Hero Cosmetics Mighty Patch](https://lovi.care/skincare/sg/p/hero-cosmetics/mighty-patch/for/oily-skin) — High fit — [S$25.75 at Amazon](https://www.amazon.sg/dp/B09NNF2DXX?tag=lovi-care-web-product0e-22&linkCode=osi&th=1&psc=1)

### [Gluconolactone](https://lovi.care/skincare/sg/ingredients/gluconolactone) products

- [SKIN1004 Madagascar Centella Toning Toner](https://lovi.care/skincare/sg/p/skin1004/madagascar-centella-toning-toner/for/combination-skin) — Superior fit — [S$18.07 at YesStyle](https://www.yesstyle.com/en/skin1004-madagascar-centella-toning-toner-210ml/info.html/pid.1077182357?curr=SGD&rco=SG)
- [BYOMA Clarifying Serum](https://lovi.care/skincare/sg/p/byoma/clarifying-serum/for/dry-skin) — High fit
- [EADEM Cashmere Peel](https://lovi.care/skincare/sg/p/eadem/cashmere-peel/for/oily-skin) — Average fit
- [The INKEY List PHA Toner](https://lovi.care/skincare/sg/p/the-inkey-list/pha-toner/for/acne-prone-skin) — Superior fit — [S$26.18 at Amazon](https://www.amazon.sg/dp/B09NB35HJB?tag=lovi-care-web-product0e-22&linkCode=osi&th=1&psc=1)
- [Kiehl's Hydro-Plumping Serum Concentrate](https://lovi.care/skincare/sg/p/kiehl-s/hydro-plumping-serum-concentrate/for/dry-skin) — Superior fit — [S$22.43 at Amazon](https://www.amazon.sg/dp/B084WR3WQX?tag=lovi-care-web-product0e-22&linkCode=osi&th=1&psc=1)
- [StriVectin Daily Reveal Exfoliating Pads](https://lovi.care/skincare/sg/p/strivectin/daily-reveal-exfoliating-pads/for/oily-skin) — Average fit
- [OLEHENRIKSEN Truth Juice Daily Cleanser](https://lovi.care/skincare/sg/p/olehenriksen/truth-juice-daily-cleanser/for/oily-acne-prone-skin) — High fit
- [Farmacy Brighten Up 3% TXA](https://lovi.care/skincare/sg/p/farmacy/brighten-up-3-txa/for/acne-prone-skin) — Average fit
- [Neutrogena Bright Boost Gel Cream](https://lovi.care/skincare/sg/p/neutrogena/bright-boost-gel-cream/for/acne-prone-skin) — High fit
- [Medik8 Press & Glow](https://lovi.care/skincare/sg/p/medik8/press-and-glow/for/dry-skin) — Superior fit
- [AXIS-Y PHA Resurfacing Glow Peel](https://lovi.care/skincare/sg/p/axis-y/pha-resurfacing-glow-peel/for/mature-skin) — Superior fit — [S$15.71 at YesStyle](https://www.yesstyle.com/en/axis-y-pha-resurfacing-glow-peel-50ml/info.html/pid.1115237803?curr=SGD&rco=SG)
- [La Roche-Posay MELA B3 Facial Gel Cleanser](https://lovi.care/skincare/sg/p/la-roche-posay/mela-b3-facial-gel-cleanser/for/sensitive-skin) — Superior fit

## Questions and answers

### Can you use salicylic acid and gluconolactone together?

Yes, you can use [salicylic acid](https://lovi.care/skincare/sg/ingredients/salicylic-acid) and [gluconolactone](https://lovi.care/skincare/sg/ingredients/gluconolactone) together because they combine for gentler exfoliation and hydration. This pairing is ideal for beginners or sensitive, acne-prone skin, and you can find both ingredients in products like Face Reality sal-C toner and CeraVe Blemish Control Cleanser.

[Clinical, Cosmetic and Investigational Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30858720/)

### Which goes first, salicylic acid or gluconolactone?

Salicylic acid and gluconolactone work well together to provide gentler exfoliation and hydration, making this combination ideal for beginners or sensitive acne-prone skin.

[Clinical, Cosmetic and Investigational Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30858720/)

### Are salicylic acid and gluconolactone good for sensitive skin?

Yes, salicylic acid and gluconolactone work well together to provide gentler exfoliation and hydration, making them ideal for sensitive, reactive, or acne-prone skin. You can find this combination in products like CeraVe Blemish Control Cleanser, Face Reality sal-C toner, and Hero Cosmetics Pore Release Blackhead Clearing Solution.

## Research on salicylic acid and gluconolactone

- [A Double-Blinded, Randomized, Vehicle-Controlled Study of the Efficacy of Moisturizer Containing Licochalcone A, Decanediol, L-Carnitine, and Salicylic Acid for Prevention of Acne Relapse in Asian Population](https://pubmed.ncbi.nlm.nih.gov/33150170/) Salicylic acid · BioMed Research International, 2020
- [The efficacy of glycolic acid, salicylic acid, gluconolactone, and licochalcone A combined with 0.1% adapalene vs adapalene monotherapy in mild-to-moderate acne vulgaris: a double-blinded within-person comparative study](https://pubmed.ncbi.nlm.nih.gov/30858720/) Gluconolactone · Clinical, Cosmetic and Investigational Dermatology, 2019
- [A comparative study of gluconolactone versus benzoyl peroxide in the treatment of acne](https://pubmed.ncbi.nlm.nih.gov/1303072/) Gluconolactone · The Australasian Journal of Dermatology, 1992
- [Efficacy of a multitargeted, salicylic acid-based dermocosmetic cream compared to benzoyl peroxide 5% in Acne vulgaris: Results from a randomized study](https://pubmed.ncbi.nlm.nih.gov/37941097/) Salicylic acid · Journal of Cosmetic Dermatology, 2024
- [A Salicylic Acid-Based Dermocosmetic is Effective as an Adjunct to Benzoyl Peroxide for Mild to Moderate Acne and as Monotherapy in Maintenance Post Benzoyl Peroxide](https://pubmed.ncbi.nlm.nih.gov/38051857/) Salicylic acid · Journal of Drugs in Dermatology, 2023
- [Clinical evaluation of the efficacy of a facial serum containing dioic acid, glycolic acid, salicylic acid, LHA, citric acid, and HEPES in treating post-inflammatory hyperchromia and controlling oily skin in patients with acne vulgaris](https://pubmed.ncbi.nlm.nih.gov/33617668/) Salicylic acid · Journal of Cosmetic Dermatology, 2021
- [Clinical tolerance and efficacy of capryloyl salicylic acid peel compared to a glycolic acid peel in subjects with fine lines/wrinkles and hyperpigmented skin](https://pubmed.ncbi.nlm.nih.gov/19146601/) Salicylic acid · Journal of Cosmetic Dermatology, 2008
- [Comparison of clindamycin 1% and benzoyl peroxide 5% gel to a novel composition containing salicylic acid, capryloyl salicylic acid, HEPES, glycolic acid, citric acid, and dioic acid in the treatment of acne vulgaris](https://pubmed.ncbi.nlm.nih.gov/23545907/) Salicylic acid · Journal of Drugs in Dermatology, 2013
- [Split-face evaluation: Gluconolactone plus oxybrasion versus gluconolactone plus microneedling. The effects on skin parameters](https://pubmed.ncbi.nlm.nih.gov/37357656/) Gluconolactone · Skin Research and Technology, 2023

## Other combinations

- Work well together: [Salicylic acid and glycerin](https://lovi.care/skincare/sg/ingredients/salicylic-acid-and-glycerin)
- Work well together: [Panthenol and salicylic acid](https://lovi.care/skincare/sg/ingredients/panthenol-and-salicylic-acid)
- Keep them apart: [Vitamin C and salicylic acid](https://lovi.care/skincare/sg/ingredients/vitamin-c-and-salicylic-acid)
- Keep them apart: [Benzoyl peroxide and salicylic acid](https://lovi.care/skincare/sg/ingredients/benzoyl-peroxide-and-salicylic-acid)
- Keep them apart: [Retinol and salicylic acid](https://lovi.care/skincare/sg/ingredients/retinol-and-salicylic-acid)
- Depends on the strength: [Niacinamide and salicylic acid](https://lovi.care/skincare/sg/ingredients/niacinamide-and-salicylic-acid)
- Work well together: [Salicylic acid and lauric acid](https://lovi.care/skincare/sg/ingredients/salicylic-acid-and-lauric-acid)
- Work well together: [Salicylic acid and linoleic acid](https://lovi.care/skincare/sg/ingredients/salicylic-acid-and-linoleic-acid)
- Depends on the strength: [Niacinamide and gluconolactone](https://lovi.care/skincare/sg/ingredients/niacinamide-and-gluconolactone)
- Work well together: [Gluconolactone and hyaluronic acid](https://lovi.care/skincare/sg/ingredients/gluconolactone-and-hyaluronic-acid)
- Depends on the strength: [Salicylic acid and zinc](https://lovi.care/skincare/sg/ingredients/salicylic-acid-and-zinc)
- Work well together: [Salicylic acid and zinc gluconate](https://lovi.care/skincare/sg/ingredients/salicylic-acid-and-zinc-gluconate)
- Work well together: [Salicylic acid and zinc oxide](https://lovi.care/skincare/sg/ingredients/salicylic-acid-and-zinc-oxide)
- Work well together: [Salicylic acid and zinc sulfate](https://lovi.care/skincare/sg/ingredients/salicylic-acid-and-zinc-sulfate)
- Keep them apart: [Salicylic acid and hyaluronic acid](https://lovi.care/skincare/sg/ingredients/salicylic-acid-and-hyaluronic-acid)
- Work well together: [AHA blend glycolic and citric acids and gluconolactone](https://lovi.care/skincare/sg/ingredients/aha-blend-glycolic-and-citric-acids-and-gluconolactone)
- Work well together: [Gluconolactone and citric acid](https://lovi.care/skincare/sg/ingredients/gluconolactone-and-citric-acid)
- Work well together: [Glycolic acid and gluconolactone](https://lovi.care/skincare/sg/ingredients/glycolic-acid-and-gluconolactone)
- Work well together: [Lactic acid and gluconolactone](https://lovi.care/skincare/sg/ingredients/lactic-acid-and-gluconolactone)
- Work well together: [Mandelic acid and gluconolactone](https://lovi.care/skincare/sg/ingredients/mandelic-acid-and-gluconolactone)
- Work well together: [Vitamin C and gluconolactone](https://lovi.care/skincare/sg/ingredients/vitamin-c-and-gluconolactone)
- Keep them apart: [Salicylic acid and acetyl hexapeptide-3](https://lovi.care/skincare/sg/ingredients/salicylic-acid-and-acetyl-hexapeptide-3)
- Keep them apart: [Salicylic acid and bio-placenta peptides](https://lovi.care/skincare/sg/ingredients/salicylic-acid-and-bio-placenta-peptides)
- Keep them apart: [Salicylic acid and collagen peptide](https://lovi.care/skincare/sg/ingredients/salicylic-acid-and-collagen-peptide)
- Keep them apart: [Salicylic acid and copper peptide](https://lovi.care/skincare/sg/ingredients/salicylic-acid-and-copper-peptide)
- Keep them apart: [Salicylic acid and hexapeptide](https://lovi.care/skincare/sg/ingredients/salicylic-acid-and-hexapeptide)
- Keep them apart: [Salicylic acid and hexapeptide-9](https://lovi.care/skincare/sg/ingredients/salicylic-acid-and-hexapeptide-9)
- Keep them apart: [Salicylic acid and palmitoyl pentapeptide-4](https://lovi.care/skincare/sg/ingredients/salicylic-acid-and-palmitoyl-pentapeptide-4)
- Keep them apart: [Salicylic acid and palmitoyl tripeptide-1](https://lovi.care/skincare/sg/ingredients/salicylic-acid-and-palmitoyl-tripeptide-1)
- Keep them apart: [Salicylic acid and peptide-rich plasma](https://lovi.care/skincare/sg/ingredients/salicylic-acid-and-peptide-rich-plasma)
- Keep them apart: [Salicylic acid and triple peptide blend](https://lovi.care/skincare/sg/ingredients/salicylic-acid-and-triple-peptide-blend)
- Work well together: [Salicylic acid and allantoin](https://lovi.care/skincare/sg/ingredients/salicylic-acid-and-allantoin)
- Work well together: [Salicylic acid and bisabolol](https://lovi.care/skincare/sg/ingredients/salicylic-acid-and-bisabolol)
- Keep them apart: [Salicylic acid and tri-ceramide complex](https://lovi.care/skincare/sg/ingredients/salicylic-acid-and-tri-ceramide-complex)
- Keep them apart: [Adapalene and salicylic acid](https://lovi.care/skincare/sg/ingredients/adapalene-and-salicylic-acid)
- Keep them apart: [Salicylic acid and granactive retinoid](https://lovi.care/skincare/sg/ingredients/salicylic-acid-and-granactive-retinoid)
- Keep them apart: [Salicylic acid and hydroxypinacolone retinoate](https://lovi.care/skincare/sg/ingredients/salicylic-acid-and-hydroxypinacolone-retinoate)
- Keep them apart: [Salicylic acid and pro-retinol](https://lovi.care/skincare/sg/ingredients/salicylic-acid-and-pro-retinol)
- Keep them apart: [Salicylic acid and retinal](https://lovi.care/skincare/sg/ingredients/salicylic-acid-and-retinal)
- Keep them apart: [Salicylic acid and retinoid blend](https://lovi.care/skincare/sg/ingredients/salicylic-acid-and-retinoid-blend)
- Keep them apart: [Salicylic acid and tretinoin](https://lovi.care/skincare/sg/ingredients/salicylic-acid-and-tretinoin)
- Work well together: [Salicylic acid and lactobionic acid](https://lovi.care/skincare/sg/ingredients/salicylic-acid-and-lactobionic-acid)
- Keep them apart: [AHA blend glycolic and citric acids and salicylic acid](https://lovi.care/skincare/sg/ingredients/aha-blend-glycolic-and-citric-acids-and-salicylic-acid)
- Keep them apart: [Salicylic acid and citric acid](https://lovi.care/skincare/sg/ingredients/salicylic-acid-and-citric-acid)
- Keep them apart: [Glycolic acid and salicylic acid](https://lovi.care/skincare/sg/ingredients/glycolic-acid-and-salicylic-acid)
- Keep them apart: [Salicylic acid and lactic acid](https://lovi.care/skincare/sg/ingredients/salicylic-acid-and-lactic-acid)
- Keep them apart: [Salicylic acid and mandelic acid](https://lovi.care/skincare/sg/ingredients/salicylic-acid-and-mandelic-acid)
- Keep them apart: [Azelaic acid and salicylic acid](https://lovi.care/skincare/sg/ingredients/azelaic-acid-and-salicylic-acid)
- Keep them apart: [Salicylic acid and titanium dioxide](https://lovi.care/skincare/sg/ingredients/salicylic-acid-and-titanium-dioxide)
- Work well together: [Green tea and salicylic acid](https://lovi.care/skincare/sg/ingredients/green-tea-and-salicylic-acid)
- Work well together: [Salicylic acid and resveratrol](https://lovi.care/skincare/sg/ingredients/salicylic-acid-and-resveratrol)
- Work well together: [Salicylic acid and vitamin E](https://lovi.care/skincare/sg/ingredients/salicylic-acid-and-vitamin-e)

## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi checks every pairing with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this pairing advice: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/ingredients/salicylic-acid-and-gluconolactone
- United Kingdom: https://lovi.care/skincare/uk/ingredients/salicylic-acid-and-gluconolactone
- Ireland: https://lovi.care/skincare/ie/ingredients/salicylic-acid-and-gluconolactone
- Germany: https://lovi.care/skincare/de/ingredients/salicylic-acid-and-gluconolactone
- France: https://lovi.care/skincare/fr/ingredients/salicylic-acid-and-gluconolactone
- Italy: https://lovi.care/skincare/it/ingredients/salicylic-acid-and-gluconolactone
- Netherlands: https://lovi.care/skincare/nl/ingredients/salicylic-acid-and-gluconolactone
- Spain: https://lovi.care/skincare/es/ingredients/salicylic-acid-and-gluconolactone
- Canada: https://lovi.care/skincare/ca/ingredients/salicylic-acid-and-gluconolactone
- Australia: https://lovi.care/skincare/au/ingredients/salicylic-acid-and-gluconolactone
- Singapore: https://lovi.care/skincare/sg/ingredients/salicylic-acid-and-gluconolactone (this page)
- Saudi Arabia: https://lovi.care/skincare/sa/ingredients/salicylic-acid-and-gluconolactone
- United Arab Emirates: https://lovi.care/skincare/ae/ingredients/salicylic-acid-and-gluconolactone