# Mandelic acid and triple peptide blend

Page: https://lovi.care/skincare/sg/ingredients/mandelic-acid-and-triple-peptide-blend

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Singapore.

Keep them apart

Use them at different times of day, applying [mandelic acid](https://lovi.care/skincare/sg/ingredients/mandelic-acid) first and the peptide blend later, because the acid is too harsh for peptides. The strong acid breaks down the peptides, which stops them from firming and smoothing your skin. You can easily fix this by using your acid in the morning and your peptides at night, or by spacing them out with more time.

- [All about mandelic acid](https://lovi.care/skincare/sg/ingredients/mandelic-acid)
- [All about triple peptide blend](https://lovi.care/skincare/sg/ingredients/triple-peptide-blend)

### [Mandelic acid](https://lovi.care/skincare/sg/ingredients/mandelic-acid) products

- [The Ordinary Mandelic Acid 10% + HA](https://lovi.care/skincare/sg/p/the-ordinary/mandelic-acid-10-ha/for/acne-prone-skin) — Superior fit
- [Nécessaire The Body Retinol](https://lovi.care/skincare/sg/p/necessaire/the-body-retinol/for/dark-spots) — Average fit
- [Good Molecules Mandelic Acid Serum](https://lovi.care/skincare/sg/p/good-molecules/mandelic-acid-serum/for/dry-sensitive-skin) — Superior fit
- [Glamglow Supermud Clearing Treatment](https://lovi.care/skincare/sg/p/glamglow/supermud-clearing-treatment/for/oily-skin) — High fit
- [Dermalogica PowerBright Dark Spot Peel](https://lovi.care/skincare/sg/p/dermalogica/powerbright-dark-spot-peel/for/oily-skin) — Average fit
- [Sofie Pavitt Face Mandelic Clearing Serum](https://lovi.care/skincare/sg/p/sofie-pavitt-face/mandelic-clearing-serum/for/oily-acne-prone-skin) — High fit
- [Cetaphil Gentle Exfoliating SA Lotion](https://lovi.care/skincare/sg/p/cetaphil/gentle-exfoliating-sa-lotion/for/combination-skin) — High fit — [S$19.91 at Amazon](https://www.amazon.sg/dp/B0CZDP1Q9H?tag=lovi-care-web-product0e-22&linkCode=osi&th=1&psc=1)
- [SkinCeuticals Cell Cycle Catalyst](https://lovi.care/skincare/sg/p/skinceuticals/cell-cycle-catalyst/for/oily-acne-prone-skin) — Average fit
- [DIME TBT Serum](https://lovi.care/skincare/sg/p/dime/tbt-serum/for/dry-sensitive-skin) — High fit
- [By Wishtrend Mandelic Acid 5% Skin Prep Water](https://lovi.care/skincare/sg/p/by-wishtrend/mandelic-acid-5-skin-prep-water/for/acne-prone-skin) — High fit
- [Haruharu Wonder Black Rice Triple AHA Gentle Cleansing Gel](https://lovi.care/skincare/sg/p/haruharu-wonder/black-rice-triple-aha-gentle-cleansing-gel/for/oily-acne-prone-skin) — High fit — [S$16.18 at YesStyle](https://www.yesstyle.com/en/haruharu-wonder-black-rice-triple-aha-gentle-cleansing-gel-100ml/info.html/pid.1125408032?curr=SGD&rco=SG)
- [Neutrogena Bright Boost Gel Cream](https://lovi.care/skincare/sg/p/neutrogena/bright-boost-gel-cream/for/acne-prone-skin) — High fit

### [Triple peptide blend](https://lovi.care/skincare/sg/ingredients/triple-peptide-blend) products

- [Drunk Elephant A-Passioni Retinol Cream](https://lovi.care/skincare/sg/p/drunk-elephant/a-passioni-retinol-cream/for/mature-skin) — High fit — [S$110.11 at Amazon](https://www.amazon.sg/dp/B08TGGGZM5?tag=lovi-care-web-product0e-22&linkCode=osi&th=1&psc=1)

## Questions and answers

### Can you use mandelic acid and triple peptide blend together?

Keep [mandelic acid](https://lovi.care/skincare/sg/ingredients/mandelic-acid) and [triple peptide blend](https://lovi.care/skincare/sg/ingredients/triple-peptide-blend) apart in your routine because the low pH of mandelic acid can destabilize peptide bonds and reduce their effectiveness. You can still use them by separating them into different steps or routines, such as using one in the morning and the other at night.

### Which goes first, mandelic acid or triple peptide blend?

Keep mandelic acid and triple peptide blend apart by using them in separate steps or routines, such as applying one in the morning and the other at night. The low pH of mandelic acid may destabilize the peptide bonds and reduce their bioactivity if combined in the same routine.

### Are mandelic acid and triple peptide blend good for sensitive skin?

No, you should keep mandelic acid and triple peptide blend apart because the low pH of the acid destabilizes peptide bonds and reduces their bioactivity, which can irritate sensitive skin. Instead, use them in separate steps or routines like AM and PM separation.

## Research on mandelic acid and triple peptide blend

- [Anti-Wrinkle Benefits of Peptides Complex Stimulating Skin Basement Membrane Proteins Expression](https://pubmed.ncbi.nlm.nih.gov/31861912/) Triple peptide blend · International Journal of Molecular Sciences, 2019
- [Comparative study of efficacy and safety of 45% mandelic acid versus 30% salicylic acid peels in mild-to-moderate acne vulgaris](https://pubmed.ncbi.nlm.nih.gov/31553119/) Mandelic acid · Journal of Cosmetic Dermatology, 2020
- [Evaluation of dermal extracellular matrix and epidermal-dermal junction modifications using matrix-assisted laser desorption/ionization mass spectrometric imaging, in vivo reflectance confocal microscopy, echography, and histology: effect of age and peptide applications](https://pubmed.ncbi.nlm.nih.gov/25817264/) Triple peptide blend · Journal of Cosmetic Dermatology, 2015
- [Chemical peels for acne vulgaris: a systematic review of randomised controlled trials](https://pubmed.ncbi.nlm.nih.gov/29705755/) Mandelic acid · BMJ Open, 2018
- [Synergistic action of a triple peptide complex on an essential extra-cellular matrix protein exhibits significant anti-aging benefits](https://pubmed.ncbi.nlm.nih.gov/20618556/) Triple peptide blend · Journal of Cosmetic Dermatology, 2010

## Other combinations

- Keep them apart: [Benzoyl peroxide and mandelic acid](https://lovi.care/skincare/sg/ingredients/benzoyl-peroxide-and-mandelic-acid)
- Keep them apart: [Retinol and mandelic acid](https://lovi.care/skincare/sg/ingredients/retinol-and-mandelic-acid)
- Depends on the strength: [Niacinamide and mandelic acid](https://lovi.care/skincare/sg/ingredients/niacinamide-and-mandelic-acid)
- Work well together: [Mandelic acid and sodium lactate](https://lovi.care/skincare/sg/ingredients/mandelic-acid-and-sodium-lactate)
- Work well together: [Mandelic acid and tromethamine](https://lovi.care/skincare/sg/ingredients/mandelic-acid-and-tromethamine)
- Keep them apart: [Adapalene and triple peptide blend](https://lovi.care/skincare/sg/ingredients/adapalene-and-triple-peptide-blend)
- Keep them apart: [Granactive retinoid and triple peptide blend](https://lovi.care/skincare/sg/ingredients/granactive-retinoid-and-triple-peptide-blend)
- Keep them apart: [Hydroxypinacolone retinoate and triple peptide blend](https://lovi.care/skincare/sg/ingredients/hydroxypinacolone-retinoate-and-triple-peptide-blend)
- Keep them apart: [Pro-retinol and triple peptide blend](https://lovi.care/skincare/sg/ingredients/pro-retinol-and-triple-peptide-blend)
- Keep them apart: [Retinal and triple peptide blend](https://lovi.care/skincare/sg/ingredients/retinal-and-triple-peptide-blend)
- Keep them apart: [Retinoid blend and triple peptide blend](https://lovi.care/skincare/sg/ingredients/retinoid-blend-and-triple-peptide-blend)
- Depends on the strength: [Retinol and triple peptide blend](https://lovi.care/skincare/sg/ingredients/retinol-and-triple-peptide-blend)
- Keep them apart: [Tretinoin and triple peptide blend](https://lovi.care/skincare/sg/ingredients/tretinoin-and-triple-peptide-blend)
- Keep them apart: [Vitamin A and triple peptide blend](https://lovi.care/skincare/sg/ingredients/vitamin-a-and-triple-peptide-blend)
- Work well together: [Liposome and triple peptide blend](https://lovi.care/skincare/sg/ingredients/liposome-and-triple-peptide-blend)
- Work well together: [Microcapsule and triple peptide blend](https://lovi.care/skincare/sg/ingredients/microcapsule-and-triple-peptide-blend)
- Keep them apart: [Vitamin C and triple peptide blend](https://lovi.care/skincare/sg/ingredients/vitamin-c-and-triple-peptide-blend)
- Work well together: [Betaine and triple peptide blend](https://lovi.care/skincare/sg/ingredients/betaine-and-triple-peptide-blend)
- Work well together: [Glycerin and triple peptide blend](https://lovi.care/skincare/sg/ingredients/glycerin-and-triple-peptide-blend)
- Work well together: [Hyaluronic acid and triple peptide blend](https://lovi.care/skincare/sg/ingredients/hyaluronic-acid-and-triple-peptide-blend)
- Work well together: [Mandelic acid and betaine](https://lovi.care/skincare/sg/ingredients/mandelic-acid-and-betaine)
- Work well together: [Glycerin and mandelic acid](https://lovi.care/skincare/sg/ingredients/glycerin-and-mandelic-acid)
- Depends on the strength: [Mandelic acid and hyaluronic acid](https://lovi.care/skincare/sg/ingredients/mandelic-acid-and-hyaluronic-acid)
- Depends on the strength: [Niacinamide and triple peptide blend](https://lovi.care/skincare/sg/ingredients/niacinamide-and-triple-peptide-blend)
- Work well together: [Panthenol and triple peptide blend](https://lovi.care/skincare/sg/ingredients/panthenol-and-triple-peptide-blend)
- Work well together: [Bakuchiol and triple peptide blend](https://lovi.care/skincare/sg/ingredients/bakuchiol-and-triple-peptide-blend)
- Work well together: [Arginine and triple peptide blend](https://lovi.care/skincare/sg/ingredients/arginine-and-triple-peptide-blend)
- Work well together: [Triple peptide blend and GABA](https://lovi.care/skincare/sg/ingredients/triple-peptide-blend-and-gaba)
- Work well together: [Silk amino acids and triple peptide blend](https://lovi.care/skincare/sg/ingredients/silk-amino-acids-and-triple-peptide-blend)
- Work well together: [Taurine and triple peptide blend](https://lovi.care/skincare/sg/ingredients/taurine-and-triple-peptide-blend)
- Work well together: [Triple peptide blend and theanine](https://lovi.care/skincare/sg/ingredients/triple-peptide-blend-and-theanine)
- Keep them apart: [AHA blend glycolic and citric acids and triple peptide blend](https://lovi.care/skincare/sg/ingredients/aha-blend-glycolic-and-citric-acids-and-triple-peptide-blend)
- Keep them apart: [Citric acid and triple peptide blend](https://lovi.care/skincare/sg/ingredients/citric-acid-and-triple-peptide-blend)
- Keep them apart: [Glycolic acid and triple peptide blend](https://lovi.care/skincare/sg/ingredients/glycolic-acid-and-triple-peptide-blend)
- Keep them apart: [Lactic acid and triple peptide blend](https://lovi.care/skincare/sg/ingredients/lactic-acid-and-triple-peptide-blend)
- Keep them apart: [Acetyl hexapeptide-3 and mandelic acid](https://lovi.care/skincare/sg/ingredients/acetyl-hexapeptide-3-and-mandelic-acid)
- Keep them apart: [Bio-placenta peptides and mandelic acid](https://lovi.care/skincare/sg/ingredients/bio-placenta-peptides-and-mandelic-acid)
- Keep them apart: [Carnosine and mandelic acid](https://lovi.care/skincare/sg/ingredients/carnosine-and-mandelic-acid)
- Keep them apart: [Mandelic acid and collagen peptide](https://lovi.care/skincare/sg/ingredients/mandelic-acid-and-collagen-peptide)
- Keep them apart: [Mandelic acid and copper peptide](https://lovi.care/skincare/sg/ingredients/mandelic-acid-and-copper-peptide)
- Keep them apart: [Hexapeptide and mandelic acid](https://lovi.care/skincare/sg/ingredients/hexapeptide-and-mandelic-acid)
- Keep them apart: [Mandelic acid and hexapeptide-9](https://lovi.care/skincare/sg/ingredients/mandelic-acid-and-hexapeptide-9)
- Keep them apart: [Mandelic acid and palmitoyl pentapeptide-4](https://lovi.care/skincare/sg/ingredients/mandelic-acid-and-palmitoyl-pentapeptide-4)
- Keep them apart: [Mandelic acid and palmitoyl tripeptide-1](https://lovi.care/skincare/sg/ingredients/mandelic-acid-and-palmitoyl-tripeptide-1)
- Keep them apart: [Mandelic acid and peptide-rich plasma](https://lovi.care/skincare/sg/ingredients/mandelic-acid-and-peptide-rich-plasma)
- Work well together: [Coenzyme Q10 and triple peptide blend](https://lovi.care/skincare/sg/ingredients/coenzyme-q10-and-triple-peptide-blend)
- Work well together: [Green tea and triple peptide blend](https://lovi.care/skincare/sg/ingredients/green-tea-and-triple-peptide-blend)
- Work well together: [Vitamin E and triple peptide blend](https://lovi.care/skincare/sg/ingredients/vitamin-e-and-triple-peptide-blend)
- Keep them apart: [Adapalene and mandelic acid](https://lovi.care/skincare/sg/ingredients/adapalene-and-mandelic-acid)
- Keep them apart: [Mandelic acid and granactive retinoid](https://lovi.care/skincare/sg/ingredients/mandelic-acid-and-granactive-retinoid)
- Keep them apart: [Mandelic acid and hydroxypinacolone retinoate](https://lovi.care/skincare/sg/ingredients/mandelic-acid-and-hydroxypinacolone-retinoate)
- Keep them apart: [Pro-retinol and mandelic acid](https://lovi.care/skincare/sg/ingredients/pro-retinol-and-mandelic-acid)
- Keep them apart: [Retinal and mandelic acid](https://lovi.care/skincare/sg/ingredients/retinal-and-mandelic-acid)
- Keep them apart: [Mandelic acid and retinoid blend](https://lovi.care/skincare/sg/ingredients/mandelic-acid-and-retinoid-blend)
- Keep them apart: [Tretinoin and mandelic acid](https://lovi.care/skincare/sg/ingredients/tretinoin-and-mandelic-acid)
- Work well together: [Beta-sitosterol and triple peptide blend](https://lovi.care/skincare/sg/ingredients/beta-sitosterol-and-triple-peptide-blend)
- Work well together: [Ceramide-building complex and triple peptide blend](https://lovi.care/skincare/sg/ingredients/ceramide-building-complex-and-triple-peptide-blend)
- Work well together: [Cholesterol and triple peptide blend](https://lovi.care/skincare/sg/ingredients/cholesterol-and-triple-peptide-blend)
- Work well together: [Phytosphingosine and triple peptide blend](https://lovi.care/skincare/sg/ingredients/phytosphingosine-and-triple-peptide-blend)
- Work well together: [Phytosterol and triple peptide blend](https://lovi.care/skincare/sg/ingredients/phytosterol-and-triple-peptide-blend)
- Work well together: [Squalene and triple peptide blend](https://lovi.care/skincare/sg/ingredients/squalene-and-triple-peptide-blend)
- Work well together: [Tri-ceramide complex and triple peptide blend](https://lovi.care/skincare/sg/ingredients/tri-ceramide-complex-and-triple-peptide-blend)
- Work well together: [Mandelic acid and gluconolactone](https://lovi.care/skincare/sg/ingredients/mandelic-acid-and-gluconolactone)
- Work well together: [Mandelic acid and lactobionic acid](https://lovi.care/skincare/sg/ingredients/mandelic-acid-and-lactobionic-acid)
- Keep them apart: [Salicylic acid and triple peptide blend](https://lovi.care/skincare/sg/ingredients/salicylic-acid-and-triple-peptide-blend)
- Work well together: [Mandelic acid and cholesterol](https://lovi.care/skincare/sg/ingredients/mandelic-acid-and-cholesterol)
- Work well together: [Mandelic acid and lauric acid](https://lovi.care/skincare/sg/ingredients/mandelic-acid-and-lauric-acid)
- Work well together: [Linoleic acid and mandelic acid](https://lovi.care/skincare/sg/ingredients/linoleic-acid-and-mandelic-acid)
- Keep them apart: [Mandelic acid and tri-ceramide complex](https://lovi.care/skincare/sg/ingredients/mandelic-acid-and-tri-ceramide-complex)
- Work well together: [Arginine and mandelic acid](https://lovi.care/skincare/sg/ingredients/arginine-and-mandelic-acid)
- Work well together: [Mandelic acid and GABA](https://lovi.care/skincare/sg/ingredients/mandelic-acid-and-gaba)
- Work well together: [Silk amino acids and mandelic acid](https://lovi.care/skincare/sg/ingredients/silk-amino-acids-and-mandelic-acid)
- Work well together: [Taurine and mandelic acid](https://lovi.care/skincare/sg/ingredients/taurine-and-mandelic-acid)
- Work well together: [Mandelic acid and theanine](https://lovi.care/skincare/sg/ingredients/mandelic-acid-and-theanine)
- Keep them apart: [Triple peptide blend and baking soda](https://lovi.care/skincare/sg/ingredients/triple-peptide-blend-and-baking-soda)
- Keep them apart: [Bleach and triple peptide blend](https://lovi.care/skincare/sg/ingredients/bleach-and-triple-peptide-blend)
- Keep them apart: [Potassium hydroxide and triple peptide blend](https://lovi.care/skincare/sg/ingredients/potassium-hydroxide-and-triple-peptide-blend)
- Keep them apart: [Behenyl alcohol and triple peptide blend](https://lovi.care/skincare/sg/ingredients/behenyl-alcohol-and-triple-peptide-blend)
- Keep them apart: [Isopropyl alcohol and triple peptide blend](https://lovi.care/skincare/sg/ingredients/isopropyl-alcohol-and-triple-peptide-blend)
- Keep them apart: [Polyvinyl alcohol and triple peptide blend](https://lovi.care/skincare/sg/ingredients/polyvinyl-alcohol-and-triple-peptide-blend)
- Work well together: [Ferulic acid and mandelic acid](https://lovi.care/skincare/sg/ingredients/ferulic-acid-and-mandelic-acid)
- Work well together: [Vitamin E and mandelic acid](https://lovi.care/skincare/sg/ingredients/vitamin-e-and-mandelic-acid)
- Keep them apart: [Copper and triple peptide blend](https://lovi.care/skincare/sg/ingredients/copper-and-triple-peptide-blend)
- Keep them apart: [Azelaic acid and mandelic acid](https://lovi.care/skincare/sg/ingredients/azelaic-acid-and-mandelic-acid)
- Keep them apart: [Salicylic acid and mandelic acid](https://lovi.care/skincare/sg/ingredients/salicylic-acid-and-mandelic-acid)
- Work well together: [Allantoin and mandelic acid](https://lovi.care/skincare/sg/ingredients/allantoin-and-mandelic-acid)
- Work well together: [Mandelic acid and bisabolol](https://lovi.care/skincare/sg/ingredients/mandelic-acid-and-bisabolol)
- Work well together: [Panthenol and mandelic acid](https://lovi.care/skincare/sg/ingredients/panthenol-and-mandelic-acid)
- Keep them apart: [Magnesium and triple peptide blend](https://lovi.care/skincare/sg/ingredients/magnesium-and-triple-peptide-blend)
- Keep them apart: [Zinc and triple peptide blend](https://lovi.care/skincare/sg/ingredients/zinc-and-triple-peptide-blend)
- Keep them apart: [Zinc sulfate and triple peptide blend](https://lovi.care/skincare/sg/ingredients/zinc-sulfate-and-triple-peptide-blend)
- Keep them apart: [Benzoyl peroxide and triple peptide blend](https://lovi.care/skincare/sg/ingredients/benzoyl-peroxide-and-triple-peptide-blend)
- Keep them apart: [Azelaic acid and triple peptide blend](https://lovi.care/skincare/sg/ingredients/azelaic-acid-and-triple-peptide-blend)
- Keep them apart: [Protease and triple peptide blend](https://lovi.care/skincare/sg/ingredients/protease-and-triple-peptide-blend)
- Keep them apart: [Superoxide dismutase and triple peptide blend](https://lovi.care/skincare/sg/ingredients/superoxide-dismutase-and-triple-peptide-blend)

## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi checks every pairing with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this pairing advice: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/ingredients/mandelic-acid-and-triple-peptide-blend
- United Kingdom: https://lovi.care/skincare/uk/ingredients/mandelic-acid-and-triple-peptide-blend
- Ireland: https://lovi.care/skincare/ie/ingredients/mandelic-acid-and-triple-peptide-blend
- Germany: https://lovi.care/skincare/de/ingredients/mandelic-acid-and-triple-peptide-blend
- France: https://lovi.care/skincare/fr/ingredients/mandelic-acid-and-triple-peptide-blend
- Italy: https://lovi.care/skincare/it/ingredients/mandelic-acid-and-triple-peptide-blend
- Netherlands: https://lovi.care/skincare/nl/ingredients/mandelic-acid-and-triple-peptide-blend
- Spain: https://lovi.care/skincare/es/ingredients/mandelic-acid-and-triple-peptide-blend
- Canada: https://lovi.care/skincare/ca/ingredients/mandelic-acid-and-triple-peptide-blend
- Australia: https://lovi.care/skincare/au/ingredients/mandelic-acid-and-triple-peptide-blend
- Singapore: https://lovi.care/skincare/sg/ingredients/mandelic-acid-and-triple-peptide-blend (this page)
- Saudi Arabia: https://lovi.care/skincare/sa/ingredients/mandelic-acid-and-triple-peptide-blend
- United Arab Emirates: https://lovi.care/skincare/ae/ingredients/mandelic-acid-and-triple-peptide-blend