# Mandelic acid and lactobionic acid

Page: https://lovi.care/skincare/sg/ingredients/mandelic-acid-and-lactobionic-acid

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Singapore.

Work well together

Use them together in the same routine, applying the [mandelic acid](https://lovi.care/skincare/sg/ingredients/mandelic-acid) first and following with the [lactobionic acid](https://lovi.care/skincare/sg/ingredients/lactobionic-acid). Mandelic acid gently exfoliates while lactobionic acid adds moisture and calms any potential redness or stinging. If your skin feels sensitive, you can try using a gentler strength or space them out over more time.

[The use of polyhydroxy acids (PHAs) in photoaged skin](https://pubmed.ncbi.nlm.nih.gov/15002656/) [A polyhydroxy acid skin care regimen provides antiaging effects comparable to an alpha-hydroxyacid regimen](https://pubmed.ncbi.nlm.nih.gov/15002657/)

- [All about mandelic acid](https://lovi.care/skincare/sg/ingredients/mandelic-acid)
- [All about lactobionic acid](https://lovi.care/skincare/sg/ingredients/lactobionic-acid)

### [Mandelic acid](https://lovi.care/skincare/sg/ingredients/mandelic-acid) products

- [The Ordinary Mandelic Acid 10% + HA](https://lovi.care/skincare/sg/p/the-ordinary/mandelic-acid-10-ha/for/acne-prone-skin) — Superior fit
- [Nécessaire The Body Retinol](https://lovi.care/skincare/sg/p/necessaire/the-body-retinol/for/dark-spots) — Average fit
- [Good Molecules Mandelic Acid Serum](https://lovi.care/skincare/sg/p/good-molecules/mandelic-acid-serum/for/dry-sensitive-skin) — Superior fit
- [Glamglow Supermud Clearing Treatment](https://lovi.care/skincare/sg/p/glamglow/supermud-clearing-treatment/for/oily-skin) — High fit
- [Dermalogica PowerBright Dark Spot Peel](https://lovi.care/skincare/sg/p/dermalogica/powerbright-dark-spot-peel/for/oily-skin) — Average fit
- [Sofie Pavitt Face Mandelic Clearing Serum](https://lovi.care/skincare/sg/p/sofie-pavitt-face/mandelic-clearing-serum/for/oily-acne-prone-skin) — High fit
- [Cetaphil Gentle Exfoliating SA Lotion](https://lovi.care/skincare/sg/p/cetaphil/gentle-exfoliating-sa-lotion/for/combination-skin) — High fit — [S$19.91 at Amazon](https://www.amazon.sg/dp/B0CZDP1Q9H?tag=lovi-care-web-product0e-22&linkCode=osi&th=1&psc=1)
- [SkinCeuticals Cell Cycle Catalyst](https://lovi.care/skincare/sg/p/skinceuticals/cell-cycle-catalyst/for/oily-acne-prone-skin) — Average fit
- [DIME TBT Serum](https://lovi.care/skincare/sg/p/dime/tbt-serum/for/dry-sensitive-skin) — High fit
- [By Wishtrend Mandelic Acid 5% Skin Prep Water](https://lovi.care/skincare/sg/p/by-wishtrend/mandelic-acid-5-skin-prep-water/for/acne-prone-skin) — High fit
- [Haruharu Wonder Black Rice Triple AHA Gentle Cleansing Gel](https://lovi.care/skincare/sg/p/haruharu-wonder/black-rice-triple-aha-gentle-cleansing-gel/for/oily-acne-prone-skin) — High fit — [S$16.18 at YesStyle](https://www.yesstyle.com/en/haruharu-wonder-black-rice-triple-aha-gentle-cleansing-gel-100ml/info.html/pid.1125408032?curr=SGD&rco=SG)
- [Neutrogena Bright Boost Gel Cream](https://lovi.care/skincare/sg/p/neutrogena/bright-boost-gel-cream/for/acne-prone-skin) — High fit

### [Lactobionic acid](https://lovi.care/skincare/sg/ingredients/lactobionic-acid) products

- [Verb Ghost Exfoliating Scalp Nectar](https://lovi.care/skincare/sg/p/verb/ghost-exfoliating-scalp-nectar/for/oily-skin) — Superior fit
- [Elemis Pro-Collagen Marine Moisture Essence](https://lovi.care/skincare/sg/p/elemis/pro-collagen-marine-moisture-essence/for/mature-skin) — Average fit
- [Skintific AHA BHA PHA LHA Peeling Solution](https://lovi.care/skincare/sg/p/skintific/aha-bha-pha-lha-peeling-solution/for/oily-acne-prone-skin) — High fit — [S$19.53 at YesStyle](https://www.yesstyle.com/en/skintific-12-aha-bha-pha-lha-peeling-solution-30ml/info.html/pid.1136493068?curr=SGD&rco=SG)
- [Benton PHA Peeling Toner](https://lovi.care/skincare/sg/p/benton/pha-peeling-toner/for/dark-spots) — Superior fit
- [VT COSMETICS Cica Skin](https://lovi.care/skincare/sg/p/vt-cosmetics/cica-skin/for/sensitive-skin) — Superior fit
- [Estée Lauder Perfectly Clean Multi-Action Toning Lotion/Refiner](https://lovi.care/skincare/sg/p/estee-lauder/perfectly-clean-multi-action-toning-lotion-refiner/for/oily-skin) — High fit
- [COSRX Full Fit Propolis Synergy Pad](https://lovi.care/skincare/sg/p/cosrx/full-fit-propolis-synergy-pad/for/mature-skin) — High fit
- [MZ Skin Cleanse & Clarify Dual Action AHA Cleanser & Mask](https://lovi.care/skincare/sg/p/mz-skin/cleanse-and-clarify-dual-action-aha-cleanser-and-mask/for/acne-prone-skin) — High fit
- [MZ Skin Radiance & Renewal Instant Clarity Refining Mask](https://lovi.care/skincare/sg/p/mz-skin/radiance-and-renewal-instant-clarity-refining-mask/for/oily-acne-prone-skin) — High fit — [S$146.08 at Amazon](https://www.amazon.sg/dp/B07JC6S9HN?tag=lovi-care-web-product0e-22&linkCode=osi&th=1&psc=1)

## Questions and answers

### Which goes first, mandelic acid or lactobionic acid?

[Mandelic acid](https://lovi.care/skincare/sg/ingredients/mandelic-acid) and [lactobionic acid](https://lovi.care/skincare/sg/ingredients/lactobionic-acid) work well together to provide gentle exfoliation and antioxidant protection. You can find both ingredients in the product Elemis Pro-Collagen Tri-Acid Peel.

## Research on mandelic acid and lactobionic acid

- [Comparative study of efficacy and safety of 45% mandelic acid versus 30% salicylic acid peels in mild-to-moderate acne vulgaris](https://pubmed.ncbi.nlm.nih.gov/31553119/) Mandelic acid · Journal of Cosmetic Dermatology, 2020
- [Chemical peels for acne vulgaris: a systematic review of randomised controlled trials](https://pubmed.ncbi.nlm.nih.gov/29705755/) Mandelic acid · BMJ Open, 2018
- [Effects of lactobionic acid peel, aluminum oxide crystal microdermabrasion, and both procedures on skin hydration, elasticity, and transepidermal water loss](https://pubmed.ncbi.nlm.nih.gov/30661294/) Lactobionic acid · Journal of Cosmetic Dermatology, 2019
- [Lactobionic acid in a natural alkylpolyglucoside-based vehicle: assessing safety and efficacy aspects in comparison to glycolic acid](https://pubmed.ncbi.nlm.nih.gov/20367666/) Lactobionic acid · Journal of Cosmetic Dermatology, 2010
- [A 10% Lactobionic acid-containing moisturizer reduces skin surface pH without irritation-An in vivo/in vitro study](https://pubmed.ncbi.nlm.nih.gov/30859734/) Lactobionic acid · Journal of Cosmetic Dermatology, 2019

## Other combinations

- Keep them apart: [Benzoyl peroxide and mandelic acid](https://lovi.care/skincare/sg/ingredients/benzoyl-peroxide-and-mandelic-acid)
- Keep them apart: [Retinol and mandelic acid](https://lovi.care/skincare/sg/ingredients/retinol-and-mandelic-acid)
- Depends on the strength: [Niacinamide and mandelic acid](https://lovi.care/skincare/sg/ingredients/niacinamide-and-mandelic-acid)
- Work well together: [Mandelic acid and sodium lactate](https://lovi.care/skincare/sg/ingredients/mandelic-acid-and-sodium-lactate)
- Work well together: [Mandelic acid and tromethamine](https://lovi.care/skincare/sg/ingredients/mandelic-acid-and-tromethamine)
- Depends on the strength: [Niacinamide and lactobionic acid](https://lovi.care/skincare/sg/ingredients/niacinamide-and-lactobionic-acid)
- Work well together: [Hyaluronic acid and lactobionic acid](https://lovi.care/skincare/sg/ingredients/hyaluronic-acid-and-lactobionic-acid)
- Work well together: [Mandelic acid and betaine](https://lovi.care/skincare/sg/ingredients/mandelic-acid-and-betaine)
- Work well together: [Glycerin and mandelic acid](https://lovi.care/skincare/sg/ingredients/glycerin-and-mandelic-acid)
- Depends on the strength: [Mandelic acid and hyaluronic acid](https://lovi.care/skincare/sg/ingredients/mandelic-acid-and-hyaluronic-acid)
- Keep them apart: [Acetyl hexapeptide-3 and mandelic acid](https://lovi.care/skincare/sg/ingredients/acetyl-hexapeptide-3-and-mandelic-acid)
- Keep them apart: [Bio-placenta peptides and mandelic acid](https://lovi.care/skincare/sg/ingredients/bio-placenta-peptides-and-mandelic-acid)
- Keep them apart: [Carnosine and mandelic acid](https://lovi.care/skincare/sg/ingredients/carnosine-and-mandelic-acid)
- Keep them apart: [Mandelic acid and collagen peptide](https://lovi.care/skincare/sg/ingredients/mandelic-acid-and-collagen-peptide)
- Keep them apart: [Mandelic acid and copper peptide](https://lovi.care/skincare/sg/ingredients/mandelic-acid-and-copper-peptide)
- Keep them apart: [Hexapeptide and mandelic acid](https://lovi.care/skincare/sg/ingredients/hexapeptide-and-mandelic-acid)
- Keep them apart: [Mandelic acid and hexapeptide-9](https://lovi.care/skincare/sg/ingredients/mandelic-acid-and-hexapeptide-9)
- Keep them apart: [Mandelic acid and palmitoyl pentapeptide-4](https://lovi.care/skincare/sg/ingredients/mandelic-acid-and-palmitoyl-pentapeptide-4)
- Keep them apart: [Mandelic acid and palmitoyl tripeptide-1](https://lovi.care/skincare/sg/ingredients/mandelic-acid-and-palmitoyl-tripeptide-1)
- Keep them apart: [Mandelic acid and peptide-rich plasma](https://lovi.care/skincare/sg/ingredients/mandelic-acid-and-peptide-rich-plasma)
- Keep them apart: [Mandelic acid and triple peptide blend](https://lovi.care/skincare/sg/ingredients/mandelic-acid-and-triple-peptide-blend)
- Keep them apart: [Adapalene and mandelic acid](https://lovi.care/skincare/sg/ingredients/adapalene-and-mandelic-acid)
- Keep them apart: [Mandelic acid and granactive retinoid](https://lovi.care/skincare/sg/ingredients/mandelic-acid-and-granactive-retinoid)
- Keep them apart: [Mandelic acid and hydroxypinacolone retinoate](https://lovi.care/skincare/sg/ingredients/mandelic-acid-and-hydroxypinacolone-retinoate)
- Keep them apart: [Pro-retinol and mandelic acid](https://lovi.care/skincare/sg/ingredients/pro-retinol-and-mandelic-acid)
- Keep them apart: [Retinal and mandelic acid](https://lovi.care/skincare/sg/ingredients/retinal-and-mandelic-acid)
- Keep them apart: [Mandelic acid and retinoid blend](https://lovi.care/skincare/sg/ingredients/mandelic-acid-and-retinoid-blend)
- Keep them apart: [Tretinoin and mandelic acid](https://lovi.care/skincare/sg/ingredients/tretinoin-and-mandelic-acid)
- Work well together: [AHA blend glycolic and citric acids and lactobionic acid](https://lovi.care/skincare/sg/ingredients/aha-blend-glycolic-and-citric-acids-and-lactobionic-acid)
- Work well together: [Lactobionic acid and citric acid](https://lovi.care/skincare/sg/ingredients/lactobionic-acid-and-citric-acid)
- Work well together: [Glycolic acid and lactobionic acid](https://lovi.care/skincare/sg/ingredients/glycolic-acid-and-lactobionic-acid)
- Work well together: [Lactic acid and lactobionic acid](https://lovi.care/skincare/sg/ingredients/lactic-acid-and-lactobionic-acid)
- Work well together: [Mandelic acid and gluconolactone](https://lovi.care/skincare/sg/ingredients/mandelic-acid-and-gluconolactone)
- Work well together: [Vitamin C and lactobionic acid](https://lovi.care/skincare/sg/ingredients/vitamin-c-and-lactobionic-acid)
- Work well together: [Mandelic acid and cholesterol](https://lovi.care/skincare/sg/ingredients/mandelic-acid-and-cholesterol)
- Work well together: [Mandelic acid and lauric acid](https://lovi.care/skincare/sg/ingredients/mandelic-acid-and-lauric-acid)
- Work well together: [Linoleic acid and mandelic acid](https://lovi.care/skincare/sg/ingredients/linoleic-acid-and-mandelic-acid)
- Keep them apart: [Mandelic acid and tri-ceramide complex](https://lovi.care/skincare/sg/ingredients/mandelic-acid-and-tri-ceramide-complex)
- Work well together: [Arginine and mandelic acid](https://lovi.care/skincare/sg/ingredients/arginine-and-mandelic-acid)
- Work well together: [Mandelic acid and GABA](https://lovi.care/skincare/sg/ingredients/mandelic-acid-and-gaba)
- Work well together: [Silk amino acids and mandelic acid](https://lovi.care/skincare/sg/ingredients/silk-amino-acids-and-mandelic-acid)
- Work well together: [Taurine and mandelic acid](https://lovi.care/skincare/sg/ingredients/taurine-and-mandelic-acid)
- Work well together: [Mandelic acid and theanine](https://lovi.care/skincare/sg/ingredients/mandelic-acid-and-theanine)
- Work well together: [Salicylic acid and lactobionic acid](https://lovi.care/skincare/sg/ingredients/salicylic-acid-and-lactobionic-acid)
- Work well together: [Ferulic acid and mandelic acid](https://lovi.care/skincare/sg/ingredients/ferulic-acid-and-mandelic-acid)
- Work well together: [Vitamin E and mandelic acid](https://lovi.care/skincare/sg/ingredients/vitamin-e-and-mandelic-acid)
- Keep them apart: [Azelaic acid and mandelic acid](https://lovi.care/skincare/sg/ingredients/azelaic-acid-and-mandelic-acid)
- Keep them apart: [Salicylic acid and mandelic acid](https://lovi.care/skincare/sg/ingredients/salicylic-acid-and-mandelic-acid)
- Work well together: [Allantoin and mandelic acid](https://lovi.care/skincare/sg/ingredients/allantoin-and-mandelic-acid)
- Work well together: [Mandelic acid and bisabolol](https://lovi.care/skincare/sg/ingredients/mandelic-acid-and-bisabolol)
- Work well together: [Panthenol and mandelic acid](https://lovi.care/skincare/sg/ingredients/panthenol-and-mandelic-acid)

## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi checks every pairing with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this pairing advice: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/ingredients/mandelic-acid-and-lactobionic-acid
- United Kingdom: https://lovi.care/skincare/uk/ingredients/mandelic-acid-and-lactobionic-acid
- Ireland: https://lovi.care/skincare/ie/ingredients/mandelic-acid-and-lactobionic-acid
- Germany: https://lovi.care/skincare/de/ingredients/mandelic-acid-and-lactobionic-acid
- France: https://lovi.care/skincare/fr/ingredients/mandelic-acid-and-lactobionic-acid
- Italy: https://lovi.care/skincare/it/ingredients/mandelic-acid-and-lactobionic-acid
- Netherlands: https://lovi.care/skincare/nl/ingredients/mandelic-acid-and-lactobionic-acid
- Spain: https://lovi.care/skincare/es/ingredients/mandelic-acid-and-lactobionic-acid
- Canada: https://lovi.care/skincare/ca/ingredients/mandelic-acid-and-lactobionic-acid
- Australia: https://lovi.care/skincare/au/ingredients/mandelic-acid-and-lactobionic-acid
- Singapore: https://lovi.care/skincare/sg/ingredients/mandelic-acid-and-lactobionic-acid (this page)
- Saudi Arabia: https://lovi.care/skincare/sa/ingredients/mandelic-acid-and-lactobionic-acid
- United Arab Emirates: https://lovi.care/skincare/ae/ingredients/mandelic-acid-and-lactobionic-acid