# Coenzyme Q10 and hexapeptide

Page: https://lovi.care/skincare/sg/ingredients/coenzyme-q10-and-hexapeptide

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Singapore.

Work well together

Use them together by applying [coenzyme Q10](https://lovi.care/skincare/sg/ingredients/coenzyme-q10) first and [hexapeptide](https://lovi.care/skincare/sg/ingredients/hexapeptide) second, because they work well as a team. Coenzyme Q10 helps keep the peptide stable so it can smooth lines better. You can use standard strengths without spacing them out.

- [All about coenzyme q10](https://lovi.care/skincare/sg/ingredients/coenzyme-q10)
- [All about hexapeptide](https://lovi.care/skincare/sg/ingredients/hexapeptide)

### [Coenzyme Q10](https://lovi.care/skincare/sg/ingredients/coenzyme-q10) products

- [Eucerin Q10 Anti-Wrinkle Face Cream](https://lovi.care/skincare/sg/p/eucerin/q10-anti-wrinkle-face-cream/for/mature-skin) — Superior fit
- [Eucerin Q10 Anti-Wrinkle Face Creme](https://lovi.care/skincare/sg/p/eucerin/q10-anti-wrinkle-face-creme/for/mature-skin) — Superior fit
- [MISSHA Time Revolution Night Repair Ampoule](https://lovi.care/skincare/sg/p/missha/time-revolution-night-repair-ampoule/for/dark-spots) — High fit
- [Timeless Coenzyme Q10 Serum](https://lovi.care/skincare/sg/p/timeless/coenzyme-q10-serum/for/oily-acne-prone-skin) — High fit
- [Eucerin Q10 Anti-Wrinkle + Pro-Retinol Night Cream](https://lovi.care/skincare/sg/p/eucerin/q10-anti-wrinkle-pro-retinol-night-cream/for/mature-skin) — High fit — [S$20.35 at Amazon](https://www.amazon.sg/dp/B0877PX27D?tag=lovi-care-web-product0e-22&linkCode=osi&th=1&psc=1)
- [Acure Radically Rejuvenating Eye Cream](https://lovi.care/skincare/sg/p/acure/radically-rejuvenating-eye-cream/for/dry-skin) — High fit
- [AGE-R Vita C Pro Ampoule](https://lovi.care/skincare/sg/p/age-r/vita-c-pro-ampoule/for/oily-skin) — High fit — [S$39.43 at Amazon](https://www.amazon.sg/dp/B0CW64R56F?tag=lovi-care-web-product0e-22&linkCode=osi&th=1&psc=1)
- [Sulwhasoo Timetreasure Renovating Eye Cream Ex](https://lovi.care/skincare/sg/p/sulwhasoo/timetreasure-renovating-eye-cream-ex/for/dry-skin) — Superior fit
- [Sulwhasoo Timetreasure Renovating Cream](https://lovi.care/skincare/sg/p/sulwhasoo/timetreasure-renovating-cream/for/mature-skin) — High fit
- [Sulwhasoo Timetreasure Renovating Cream Ex](https://lovi.care/skincare/sg/p/sulwhasoo/timetreasure-renovating-cream-ex/for/mature-skin) — High fit
- [Sunday Riley A+ High-Dose Retinoid Serum](https://lovi.care/skincare/sg/p/sunday-riley/a-high-dose-retinoid-serum/for/oily-acne-prone-skin) — High fit — [S$119.36 at Amazon](https://www.amazon.sg/dp/B07T53TFGM?tag=lovi-care-web-product0e-22&linkCode=osi&th=1&psc=1)

### [Hexapeptide](https://lovi.care/skincare/sg/ingredients/hexapeptide) products

- [SkinCeuticals P-TOX](https://lovi.care/skincare/sg/p/skinceuticals/p-tox/for/mature-skin) — High fit

## Questions and answers

### Can you use coenzyme q10 and hexapeptide together?

Yes, [coenzyme q10](https://lovi.care/skincare/sg/ingredients/coenzyme-q10) and [hexapeptide](https://lovi.care/skincare/sg/ingredients/hexapeptide) work well together because antioxidants stabilize peptides and enhance anti-aging performance. Lovi rates the fit as Superior.

### Which goes first, coenzyme q10 or hexapeptide?

Coenzyme Q10 and hexapeptide work well together, and you can use them as part of your routine to help protect against oxidative damage and smooth wrinkles.

[American Journal of Clinical Dermatology, 2013](https://pubmed.ncbi.nlm.nih.gov/23417317/) [Journal of Cosmetic Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28371204/)

### Are coenzyme q10 and hexapeptide good for sensitive skin?

Coenzyme Q10 and hexapeptide work well together, offering synergistic protection against oxidative degradation for mature, photoaged, and stressed skin.

## Research on coenzyme q10 and hexapeptide

- [Aging skin is functionally anaerobic: importance of coenzyme Q10 for anti aging skin care](https://pubmed.ncbi.nlm.nih.gov/19096122/) Coenzyme Q10 · BioFactors, 2008
- [Topical treatment with coenzyme Q10-containing formulas improves skin's Q10 level and provides antioxidative effects](https://pubmed.ncbi.nlm.nih.gov/26648450/) Coenzyme Q10 · BioFactors, 2015
- [The anti-wrinkle efficacy of argireline, a synthetic hexapeptide, in Chinese subjects: a randomized, placebo-controlled study](https://pubmed.ncbi.nlm.nih.gov/23417317/) Hexapeptide · American Journal of Clinical Dermatology, 2013
- [A randomized, single-blinded trial of a tripeptide/hexapeptide healing regimen following laser resurfacing of the face](https://pubmed.ncbi.nlm.nih.gov/28371204/) Hexapeptide · Journal of Cosmetic Dermatology, 2017
- [Anti-Wrinkle Efficacy of Cross-Linked Hyaluronic Acid-Based Microneedle Patch with Acetyl Hexapeptide-8 and Epidermal Growth Factor on Korean Skin](https://pubmed.ncbi.nlm.nih.gov/33911590/) Hexapeptide · Annals of Dermatology, 2019

## Other combinations

- Keep them apart: [Adapalene and hexapeptide](https://lovi.care/skincare/sg/ingredients/adapalene-and-hexapeptide)
- Keep them apart: [Hexapeptide and granactive retinoid](https://lovi.care/skincare/sg/ingredients/hexapeptide-and-granactive-retinoid)
- Keep them apart: [Hexapeptide and hydroxypinacolone retinoate](https://lovi.care/skincare/sg/ingredients/hexapeptide-and-hydroxypinacolone-retinoate)
- Keep them apart: [Hexapeptide and pro-retinol](https://lovi.care/skincare/sg/ingredients/hexapeptide-and-pro-retinol)
- Keep them apart: [Hexapeptide and retinal](https://lovi.care/skincare/sg/ingredients/hexapeptide-and-retinal)
- Keep them apart: [Hexapeptide and retinoid blend](https://lovi.care/skincare/sg/ingredients/hexapeptide-and-retinoid-blend)
- Depends on the strength: [Retinol and hexapeptide](https://lovi.care/skincare/sg/ingredients/retinol-and-hexapeptide)
- Keep them apart: [Tretinoin and hexapeptide](https://lovi.care/skincare/sg/ingredients/tretinoin-and-hexapeptide)
- Keep them apart: [Hexapeptide and vitamin A](https://lovi.care/skincare/sg/ingredients/hexapeptide-and-vitamin-a)
- Work well together: [Hexapeptide and liposome](https://lovi.care/skincare/sg/ingredients/hexapeptide-and-liposome)
- Work well together: [Hexapeptide and microcapsule](https://lovi.care/skincare/sg/ingredients/hexapeptide-and-microcapsule)
- Depends on the strength: [Vitamin C and hexapeptide](https://lovi.care/skincare/sg/ingredients/vitamin-c-and-hexapeptide)
- Work well together: [Hexapeptide and betaine](https://lovi.care/skincare/sg/ingredients/hexapeptide-and-betaine)
- Work well together: [Glycerin and hexapeptide](https://lovi.care/skincare/sg/ingredients/glycerin-and-hexapeptide)
- Work well together: [Hexapeptide and hyaluronic acid](https://lovi.care/skincare/sg/ingredients/hexapeptide-and-hyaluronic-acid)
- Work well together: [Coenzyme Q10 and hyaluronic acid](https://lovi.care/skincare/sg/ingredients/coenzyme-q10-and-hyaluronic-acid)
- Depends on the strength: [Niacinamide and hexapeptide](https://lovi.care/skincare/sg/ingredients/niacinamide-and-hexapeptide)
- Work well together: [Panthenol and hexapeptide](https://lovi.care/skincare/sg/ingredients/panthenol-and-hexapeptide)
- Work well together: [Bakuchiol and hexapeptide](https://lovi.care/skincare/sg/ingredients/bakuchiol-and-hexapeptide)
- Work well together: [Retinol and coenzyme q10](https://lovi.care/skincare/sg/ingredients/retinol-and-coenzyme-q10)
- Work well together: [Hexapeptide and arginine](https://lovi.care/skincare/sg/ingredients/hexapeptide-and-arginine)
- Work well together: [Hexapeptide and GABA](https://lovi.care/skincare/sg/ingredients/hexapeptide-and-gaba)
- Work well together: [Hexapeptide and silk amino acids](https://lovi.care/skincare/sg/ingredients/hexapeptide-and-silk-amino-acids)
- Work well together: [Hexapeptide and taurine](https://lovi.care/skincare/sg/ingredients/hexapeptide-and-taurine)
- Work well together: [Hexapeptide and theanine](https://lovi.care/skincare/sg/ingredients/hexapeptide-and-theanine)
- Keep them apart: [AHA blend glycolic and citric acids and hexapeptide](https://lovi.care/skincare/sg/ingredients/aha-blend-glycolic-and-citric-acids-and-hexapeptide)
- Keep them apart: [Hexapeptide and citric acid](https://lovi.care/skincare/sg/ingredients/hexapeptide-and-citric-acid)
- Keep them apart: [Glycolic acid and hexapeptide](https://lovi.care/skincare/sg/ingredients/glycolic-acid-and-hexapeptide)
- Keep them apart: [Hexapeptide and lactic acid](https://lovi.care/skincare/sg/ingredients/hexapeptide-and-lactic-acid)
- Keep them apart: [Hexapeptide and mandelic acid](https://lovi.care/skincare/sg/ingredients/hexapeptide-and-mandelic-acid)
- Work well together: [Coenzyme Q10 and acetyl hexapeptide-3](https://lovi.care/skincare/sg/ingredients/coenzyme-q10-and-acetyl-hexapeptide-3)
- Work well together: [Bio-placenta peptides and coenzyme q10](https://lovi.care/skincare/sg/ingredients/bio-placenta-peptides-and-coenzyme-q10)
- Work well together: [Coenzyme Q10 and collagen peptide](https://lovi.care/skincare/sg/ingredients/coenzyme-q10-and-collagen-peptide)
- Work well together: [Coenzyme Q10 and copper peptide](https://lovi.care/skincare/sg/ingredients/coenzyme-q10-and-copper-peptide)
- Work well together: [Green tea and hexapeptide](https://lovi.care/skincare/sg/ingredients/green-tea-and-hexapeptide)
- Work well together: [Vitamin E and hexapeptide](https://lovi.care/skincare/sg/ingredients/vitamin-e-and-hexapeptide)
- Work well together: [Coenzyme Q10 and hexapeptide-9](https://lovi.care/skincare/sg/ingredients/coenzyme-q10-and-hexapeptide-9)
- Work well together: [Coenzyme Q10 and palmitoyl pentapeptide-4](https://lovi.care/skincare/sg/ingredients/coenzyme-q10-and-palmitoyl-pentapeptide-4)
- Work well together: [Coenzyme Q10 and palmitoyl tripeptide-1](https://lovi.care/skincare/sg/ingredients/coenzyme-q10-and-palmitoyl-tripeptide-1)
- Work well together: [Coenzyme Q10 and peptide-rich plasma](https://lovi.care/skincare/sg/ingredients/coenzyme-q10-and-peptide-rich-plasma)
- Work well together: [Coenzyme Q10 and triple peptide blend](https://lovi.care/skincare/sg/ingredients/coenzyme-q10-and-triple-peptide-blend)
- Work well together: [Coenzyme Q10 and tri-ceramide complex](https://lovi.care/skincare/sg/ingredients/coenzyme-q10-and-tri-ceramide-complex)
- Work well together: [Hexapeptide and beta-sitosterol](https://lovi.care/skincare/sg/ingredients/hexapeptide-and-beta-sitosterol)
- Work well together: [Ceramide-building complex and hexapeptide](https://lovi.care/skincare/sg/ingredients/ceramide-building-complex-and-hexapeptide)
- Work well together: [Hexapeptide and cholesterol](https://lovi.care/skincare/sg/ingredients/hexapeptide-and-cholesterol)
- Work well together: [Hexapeptide and phytosphingosine](https://lovi.care/skincare/sg/ingredients/hexapeptide-and-phytosphingosine)
- Work well together: [Hexapeptide and phytosterol](https://lovi.care/skincare/sg/ingredients/hexapeptide-and-phytosterol)
- Work well together: [Hexapeptide and squalene](https://lovi.care/skincare/sg/ingredients/hexapeptide-and-squalene)
- Work well together: [Hexapeptide and tri-ceramide complex](https://lovi.care/skincare/sg/ingredients/hexapeptide-and-tri-ceramide-complex)
- Keep them apart: [Salicylic acid and hexapeptide](https://lovi.care/skincare/sg/ingredients/salicylic-acid-and-hexapeptide)
- Keep them apart: [Hexapeptide and baking soda](https://lovi.care/skincare/sg/ingredients/hexapeptide-and-baking-soda)
- Keep them apart: [Hexapeptide and bleach](https://lovi.care/skincare/sg/ingredients/hexapeptide-and-bleach)
- Keep them apart: [Hexapeptide and potassium hydroxide](https://lovi.care/skincare/sg/ingredients/hexapeptide-and-potassium-hydroxide)
- Keep them apart: [Hexapeptide and behenyl alcohol](https://lovi.care/skincare/sg/ingredients/hexapeptide-and-behenyl-alcohol)
- Keep them apart: [Hexapeptide and isopropyl alcohol](https://lovi.care/skincare/sg/ingredients/hexapeptide-and-isopropyl-alcohol)
- Keep them apart: [Hexapeptide and polyvinyl alcohol](https://lovi.care/skincare/sg/ingredients/hexapeptide-and-polyvinyl-alcohol)
- Keep them apart: [Hexapeptide and copper](https://lovi.care/skincare/sg/ingredients/hexapeptide-and-copper)
- Keep them apart: [Hexapeptide and magnesium](https://lovi.care/skincare/sg/ingredients/hexapeptide-and-magnesium)
- Keep them apart: [Hexapeptide and zinc](https://lovi.care/skincare/sg/ingredients/hexapeptide-and-zinc)
- Keep them apart: [Hexapeptide and zinc sulfate](https://lovi.care/skincare/sg/ingredients/hexapeptide-and-zinc-sulfate)
- Keep them apart: [Benzoyl peroxide and hexapeptide](https://lovi.care/skincare/sg/ingredients/benzoyl-peroxide-and-hexapeptide)
- Keep them apart: [Azelaic acid and hexapeptide](https://lovi.care/skincare/sg/ingredients/azelaic-acid-and-hexapeptide)
- Keep them apart: [Hexapeptide and protease](https://lovi.care/skincare/sg/ingredients/hexapeptide-and-protease)
- Keep them apart: [Hexapeptide and superoxide dismutase](https://lovi.care/skincare/sg/ingredients/hexapeptide-and-superoxide-dismutase)

## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi checks every pairing with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this pairing advice: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/ingredients/coenzyme-q10-and-hexapeptide
- United Kingdom: https://lovi.care/skincare/uk/ingredients/coenzyme-q10-and-hexapeptide
- Ireland: https://lovi.care/skincare/ie/ingredients/coenzyme-q10-and-hexapeptide
- Germany: https://lovi.care/skincare/de/ingredients/coenzyme-q10-and-hexapeptide
- France: https://lovi.care/skincare/fr/ingredients/coenzyme-q10-and-hexapeptide
- Italy: https://lovi.care/skincare/it/ingredients/coenzyme-q10-and-hexapeptide
- Netherlands: https://lovi.care/skincare/nl/ingredients/coenzyme-q10-and-hexapeptide
- Spain: https://lovi.care/skincare/es/ingredients/coenzyme-q10-and-hexapeptide
- Canada: https://lovi.care/skincare/ca/ingredients/coenzyme-q10-and-hexapeptide
- Australia: https://lovi.care/skincare/au/ingredients/coenzyme-q10-and-hexapeptide
- Singapore: https://lovi.care/skincare/sg/ingredients/coenzyme-q10-and-hexapeptide (this page)
- Saudi Arabia: https://lovi.care/skincare/sa/ingredients/coenzyme-q10-and-hexapeptide
- United Arab Emirates: https://lovi.care/skincare/ae/ingredients/coenzyme-q10-and-hexapeptide