# Coenzyme Q10 and acetyl hexapeptide-3

Page: https://lovi.care/skincare/sg/ingredients/coenzyme-q10-and-acetyl-hexapeptide-3

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Singapore.

Work well together

Use them together in the same routine, applying the [coenzyme Q10](https://lovi.care/skincare/sg/ingredients/coenzyme-q10) first and the peptide second for the best anti-aging results. Coenzyme Q10 protects the peptides from breaking down, while the peptides help firm and smooth the skin. No changes are needed since this pairing is gentle and stable for daily use.

- [All about coenzyme q10](https://lovi.care/skincare/sg/ingredients/coenzyme-q10)
- [All about acetyl hexapeptide-3](https://lovi.care/skincare/sg/ingredients/acetyl-hexapeptide-3)

### [Coenzyme Q10](https://lovi.care/skincare/sg/ingredients/coenzyme-q10) products

- [Eucerin Q10 Anti-Wrinkle Face Cream](https://lovi.care/skincare/sg/p/eucerin/q10-anti-wrinkle-face-cream/for/mature-skin) — Superior fit
- [Eucerin Q10 Anti-Wrinkle Face Creme](https://lovi.care/skincare/sg/p/eucerin/q10-anti-wrinkle-face-creme/for/mature-skin) — Superior fit
- [MISSHA Time Revolution Night Repair Ampoule](https://lovi.care/skincare/sg/p/missha/time-revolution-night-repair-ampoule/for/dark-spots) — High fit
- [Timeless Coenzyme Q10 Serum](https://lovi.care/skincare/sg/p/timeless/coenzyme-q10-serum/for/oily-acne-prone-skin) — High fit
- [Eucerin Q10 Anti-Wrinkle + Pro-Retinol Night Cream](https://lovi.care/skincare/sg/p/eucerin/q10-anti-wrinkle-pro-retinol-night-cream/for/mature-skin) — High fit — [S$20.35 at Amazon](https://www.amazon.sg/dp/B0877PX27D?tag=lovi-care-web-product0e-22&linkCode=osi&th=1&psc=1)
- [Acure Radically Rejuvenating Eye Cream](https://lovi.care/skincare/sg/p/acure/radically-rejuvenating-eye-cream/for/dry-skin) — High fit
- [AGE-R Vita C Pro Ampoule](https://lovi.care/skincare/sg/p/age-r/vita-c-pro-ampoule/for/oily-skin) — High fit — [S$39.43 at Amazon](https://www.amazon.sg/dp/B0CW64R56F?tag=lovi-care-web-product0e-22&linkCode=osi&th=1&psc=1)
- [Sulwhasoo Timetreasure Renovating Eye Cream Ex](https://lovi.care/skincare/sg/p/sulwhasoo/timetreasure-renovating-eye-cream-ex/for/dry-skin) — Superior fit
- [Sulwhasoo Timetreasure Renovating Cream](https://lovi.care/skincare/sg/p/sulwhasoo/timetreasure-renovating-cream/for/mature-skin) — High fit
- [Sulwhasoo Timetreasure Renovating Cream Ex](https://lovi.care/skincare/sg/p/sulwhasoo/timetreasure-renovating-cream-ex/for/mature-skin) — High fit
- [Sunday Riley A+ High-Dose Retinoid Serum](https://lovi.care/skincare/sg/p/sunday-riley/a-high-dose-retinoid-serum/for/oily-acne-prone-skin) — High fit — [S$119.36 at Amazon](https://www.amazon.sg/dp/B07T53TFGM?tag=lovi-care-web-product0e-22&linkCode=osi&th=1&psc=1)

### [Acetyl hexapeptide-3](https://lovi.care/skincare/sg/ingredients/acetyl-hexapeptide-3) products

- [The Ordinary Multi-Peptide + Copper Peptides 1% Serum](https://lovi.care/skincare/sg/p/the-ordinary/multi-peptide-copper-peptides-1-serum/for/mature-skin) — High fit
- [The Ordinary Multi-Peptide + HA Serum](https://lovi.care/skincare/sg/p/the-ordinary/multi-peptide-ha-serum/for/dry-skin) — Superior fit
- [Medik8 Liquid Peptides](https://lovi.care/skincare/sg/p/medik8/liquid-peptides/for/oily-acne-prone-skin) — Average fit
- [La Mer The Treatment Lotion](https://lovi.care/skincare/sg/p/la-mer/the-treatment-lotion/for/mature-skin) — Superior fit — [S$238.16 at Amazon](https://www.amazon.sg/dp/B076ZQ7YVB?tag=lovi-care-web-product0e-22&linkCode=osi&th=1&psc=1)
- [Rhode Peptide Glazing Fluid](https://lovi.care/skincare/sg/p/rhode/peptide-glazing-fluid/for/mature-skin) — High fit
- [The Ordinary Argireline Solution 10%](https://lovi.care/skincare/sg/p/the-ordinary/argireline-solution-10/for/mature-skin) — Average fit
- [Good Molecules Super Peptide Serum](https://lovi.care/skincare/sg/p/good-molecules/super-peptide-serum/for/mature-skin) — High fit — [S$38.42 at Amazon](https://www.amazon.sg/dp/B091MTKS35?tag=lovi-care-web-product0e-22&linkCode=osi&th=1&psc=1)
- [Clinique Smart Clinical Repair Wrinkle Correcting Serum](https://lovi.care/skincare/sg/p/clinique/smart-clinical-repair-wrinkle-correcting-serum/for/mature-skin) — Average fit
- [La Mer The Renewal Oil](https://lovi.care/skincare/sg/p/la-mer/the-renewal-oil/for/mature-skin) — High fit — [S$466.85 at Amazon](https://www.amazon.sg/dp/B0163GAMI4?tag=lovi-care-web-product0e-22&linkCode=osi&th=1&psc=1)
- [Estée Lauder Micro Essence Treatment Lotion](https://lovi.care/skincare/sg/p/estee-lauder/micro-essence-treatment-lotion/for/oily-acne-prone-skin) — Superior fit
- [The INKEY List Collagen Peptide Serum](https://lovi.care/skincare/sg/p/the-inkey-list/collagen-peptide-serum/for/dry-sensitive-skin) — High fit
- [La Mer The Eye Concentrate](https://lovi.care/skincare/sg/p/la-mer/the-eye-concentrate/for/mature-skin) — High fit — [S$337.38 at Amazon](https://www.amazon.sg/dp/B00438A000?tag=lovi-care-web-product0e-22&linkCode=osi&th=1&psc=1)

## Questions and answers

### Can you use coenzyme q10 and acetyl hexapeptide-3 together?

Yes, you can use [coenzyme q10](https://lovi.care/skincare/sg/ingredients/coenzyme-q10) and [acetyl hexapeptide-3](https://lovi.care/skincare/sg/ingredients/acetyl-hexapeptide-3) together because they offer synergistic protection against oxidative degradation. This combination helps stabilize the ingredients and enhances anti-aging performance for mature, photoaged, and stressed skin.

### Which goes first, coenzyme q10 or acetyl hexapeptide-3?

Coenzyme Q10 and acetyl hexapeptide-3 work well together, and you can apply either ingredient first or use them mixed in your routine. Antioxidants like coenzyme Q10 help stabilize peptides and enhance their anti-aging performance.

### Are coenzyme q10 and acetyl hexapeptide-3 good for sensitive skin?

Coenzyme Q10 and acetyl hexapeptide-3 work well together to provide synergistic protection against oxidative degradation and help combat signs of aging. Antioxidants help stabilize peptides and enhance anti-aging performance.

## Research on coenzyme q10 and acetyl hexapeptide-3

- [Aging skin is functionally anaerobic: importance of coenzyme Q10 for anti aging skin care](https://pubmed.ncbi.nlm.nih.gov/19096122/) Coenzyme Q10 · BioFactors, 2008
- [Topical treatment with coenzyme Q10-containing formulas improves skin's Q10 level and provides antioxidative effects](https://pubmed.ncbi.nlm.nih.gov/26648450/) Coenzyme Q10 · BioFactors, 2015
- [The anti-wrinkle efficacy of argireline, a synthetic hexapeptide, in Chinese subjects: a randomized, placebo-controlled study](https://pubmed.ncbi.nlm.nih.gov/23417317/) Acetyl hexapeptide-3 · American Journal of Clinical Dermatology, 2013
- [Anti-Wrinkle Efficacy of Cross-Linked Hyaluronic Acid-Based Microneedle Patch with Acetyl Hexapeptide-8 and Epidermal Growth Factor on Korean Skin](https://pubmed.ncbi.nlm.nih.gov/33911590/) Acetyl hexapeptide-3 · Annals of Dermatology, 2019
- [The efficacy study of the combination of tripeptide-10-citrulline and acetyl hexapeptide-3. A prospective, randomized controlled study](https://pubmed.ncbi.nlm.nih.gov/28150423/) Acetyl hexapeptide-3 · Journal of Cosmetic Dermatology, 2017
- [The anti wrinkle efficacy of synthetic hexapeptide (Argireline) in Chinese Subjects](https://pubmed.ncbi.nlm.nih.gov/23607739/) Acetyl hexapeptide-3 · Journal of Cosmetic and Laser Therapy, 2013

## Other combinations

- Keep them apart: [Adapalene and acetyl hexapeptide-3](https://lovi.care/skincare/sg/ingredients/adapalene-and-acetyl-hexapeptide-3)
- Keep them apart: [Acetyl hexapeptide-3 and granactive retinoid](https://lovi.care/skincare/sg/ingredients/acetyl-hexapeptide-3-and-granactive-retinoid)
- Keep them apart: [Acetyl hexapeptide-3 and hydroxypinacolone retinoate](https://lovi.care/skincare/sg/ingredients/acetyl-hexapeptide-3-and-hydroxypinacolone-retinoate)
- Keep them apart: [Pro-retinol and acetyl hexapeptide-3](https://lovi.care/skincare/sg/ingredients/pro-retinol-and-acetyl-hexapeptide-3)
- Keep them apart: [Retinal and acetyl hexapeptide-3](https://lovi.care/skincare/sg/ingredients/retinal-and-acetyl-hexapeptide-3)
- Keep them apart: [Acetyl hexapeptide-3 and retinoid blend](https://lovi.care/skincare/sg/ingredients/acetyl-hexapeptide-3-and-retinoid-blend)
- Depends on the strength: [Retinol and acetyl hexapeptide-3](https://lovi.care/skincare/sg/ingredients/retinol-and-acetyl-hexapeptide-3)
- Keep them apart: [Tretinoin and acetyl hexapeptide-3](https://lovi.care/skincare/sg/ingredients/tretinoin-and-acetyl-hexapeptide-3)
- Keep them apart: [Vitamin A and acetyl hexapeptide-3](https://lovi.care/skincare/sg/ingredients/vitamin-a-and-acetyl-hexapeptide-3)
- Work well together: [Liposome and acetyl hexapeptide-3](https://lovi.care/skincare/sg/ingredients/liposome-and-acetyl-hexapeptide-3)
- Work well together: [Acetyl hexapeptide-3 and microcapsule](https://lovi.care/skincare/sg/ingredients/acetyl-hexapeptide-3-and-microcapsule)
- Depends on the strength: [Vitamin C and acetyl hexapeptide-3](https://lovi.care/skincare/sg/ingredients/vitamin-c-and-acetyl-hexapeptide-3)
- Work well together: [Acetyl hexapeptide-3 and betaine](https://lovi.care/skincare/sg/ingredients/acetyl-hexapeptide-3-and-betaine)
- Work well together: [Glycerin and acetyl hexapeptide-3](https://lovi.care/skincare/sg/ingredients/glycerin-and-acetyl-hexapeptide-3)
- Work well together: [Acetyl hexapeptide-3 and hyaluronic acid](https://lovi.care/skincare/sg/ingredients/acetyl-hexapeptide-3-and-hyaluronic-acid)
- Work well together: [Coenzyme Q10 and hyaluronic acid](https://lovi.care/skincare/sg/ingredients/coenzyme-q10-and-hyaluronic-acid)
- Depends on the strength: [Niacinamide and acetyl hexapeptide-3](https://lovi.care/skincare/sg/ingredients/niacinamide-and-acetyl-hexapeptide-3)
- Work well together: [Panthenol and acetyl hexapeptide-3](https://lovi.care/skincare/sg/ingredients/panthenol-and-acetyl-hexapeptide-3)
- Work well together: [Bakuchiol and acetyl hexapeptide-3](https://lovi.care/skincare/sg/ingredients/bakuchiol-and-acetyl-hexapeptide-3)
- Work well together: [Retinol and coenzyme q10](https://lovi.care/skincare/sg/ingredients/retinol-and-coenzyme-q10)
- Work well together: [Arginine and acetyl hexapeptide-3](https://lovi.care/skincare/sg/ingredients/arginine-and-acetyl-hexapeptide-3)
- Work well together: [Acetyl hexapeptide-3 and GABA](https://lovi.care/skincare/sg/ingredients/acetyl-hexapeptide-3-and-gaba)
- Work well together: [Silk amino acids and acetyl hexapeptide-3](https://lovi.care/skincare/sg/ingredients/silk-amino-acids-and-acetyl-hexapeptide-3)
- Work well together: [Taurine and acetyl hexapeptide-3](https://lovi.care/skincare/sg/ingredients/taurine-and-acetyl-hexapeptide-3)
- Work well together: [Acetyl hexapeptide-3 and theanine](https://lovi.care/skincare/sg/ingredients/acetyl-hexapeptide-3-and-theanine)
- Keep them apart: [AHA blend glycolic and citric acids and acetyl hexapeptide-3](https://lovi.care/skincare/sg/ingredients/aha-blend-glycolic-and-citric-acids-and-acetyl-hexapeptide-3)
- Keep them apart: [Acetyl hexapeptide-3 and citric acid](https://lovi.care/skincare/sg/ingredients/acetyl-hexapeptide-3-and-citric-acid)
- Keep them apart: [Glycolic acid and acetyl hexapeptide-3](https://lovi.care/skincare/sg/ingredients/glycolic-acid-and-acetyl-hexapeptide-3)
- Keep them apart: [Lactic acid and acetyl hexapeptide-3](https://lovi.care/skincare/sg/ingredients/lactic-acid-and-acetyl-hexapeptide-3)
- Keep them apart: [Acetyl hexapeptide-3 and mandelic acid](https://lovi.care/skincare/sg/ingredients/acetyl-hexapeptide-3-and-mandelic-acid)
- Work well together: [Green tea and acetyl hexapeptide-3](https://lovi.care/skincare/sg/ingredients/green-tea-and-acetyl-hexapeptide-3)
- Work well together: [Vitamin E and acetyl hexapeptide-3](https://lovi.care/skincare/sg/ingredients/vitamin-e-and-acetyl-hexapeptide-3)
- Work well together: [Bio-placenta peptides and coenzyme q10](https://lovi.care/skincare/sg/ingredients/bio-placenta-peptides-and-coenzyme-q10)
- Work well together: [Coenzyme Q10 and collagen peptide](https://lovi.care/skincare/sg/ingredients/coenzyme-q10-and-collagen-peptide)
- Work well together: [Coenzyme Q10 and copper peptide](https://lovi.care/skincare/sg/ingredients/coenzyme-q10-and-copper-peptide)
- Work well together: [Coenzyme Q10 and hexapeptide](https://lovi.care/skincare/sg/ingredients/coenzyme-q10-and-hexapeptide)
- Work well together: [Coenzyme Q10 and hexapeptide-9](https://lovi.care/skincare/sg/ingredients/coenzyme-q10-and-hexapeptide-9)
- Work well together: [Coenzyme Q10 and palmitoyl pentapeptide-4](https://lovi.care/skincare/sg/ingredients/coenzyme-q10-and-palmitoyl-pentapeptide-4)
- Work well together: [Coenzyme Q10 and palmitoyl tripeptide-1](https://lovi.care/skincare/sg/ingredients/coenzyme-q10-and-palmitoyl-tripeptide-1)
- Work well together: [Coenzyme Q10 and peptide-rich plasma](https://lovi.care/skincare/sg/ingredients/coenzyme-q10-and-peptide-rich-plasma)
- Work well together: [Coenzyme Q10 and triple peptide blend](https://lovi.care/skincare/sg/ingredients/coenzyme-q10-and-triple-peptide-blend)
- Work well together: [Coenzyme Q10 and tri-ceramide complex](https://lovi.care/skincare/sg/ingredients/coenzyme-q10-and-tri-ceramide-complex)
- Work well together: [Acetyl hexapeptide-3 and beta-sitosterol](https://lovi.care/skincare/sg/ingredients/acetyl-hexapeptide-3-and-beta-sitosterol)
- Work well together: [Ceramide-building complex and acetyl hexapeptide-3](https://lovi.care/skincare/sg/ingredients/ceramide-building-complex-and-acetyl-hexapeptide-3)
- Work well together: [Acetyl hexapeptide-3 and cholesterol](https://lovi.care/skincare/sg/ingredients/acetyl-hexapeptide-3-and-cholesterol)
- Work well together: [Acetyl hexapeptide-3 and phytosphingosine](https://lovi.care/skincare/sg/ingredients/acetyl-hexapeptide-3-and-phytosphingosine)
- Work well together: [Acetyl hexapeptide-3 and phytosterol](https://lovi.care/skincare/sg/ingredients/acetyl-hexapeptide-3-and-phytosterol)
- Work well together: [Acetyl hexapeptide-3 and squalene](https://lovi.care/skincare/sg/ingredients/acetyl-hexapeptide-3-and-squalene)
- Work well together: [Acetyl hexapeptide-3 and tri-ceramide complex](https://lovi.care/skincare/sg/ingredients/acetyl-hexapeptide-3-and-tri-ceramide-complex)
- Keep them apart: [Salicylic acid and acetyl hexapeptide-3](https://lovi.care/skincare/sg/ingredients/salicylic-acid-and-acetyl-hexapeptide-3)
- Keep them apart: [Acetyl hexapeptide-3 and baking soda](https://lovi.care/skincare/sg/ingredients/acetyl-hexapeptide-3-and-baking-soda)
- Keep them apart: [Acetyl hexapeptide-3 and bleach](https://lovi.care/skincare/sg/ingredients/acetyl-hexapeptide-3-and-bleach)
- Keep them apart: [Acetyl hexapeptide-3 and potassium hydroxide](https://lovi.care/skincare/sg/ingredients/acetyl-hexapeptide-3-and-potassium-hydroxide)
- Keep them apart: [Acetyl hexapeptide-3 and behenyl alcohol](https://lovi.care/skincare/sg/ingredients/acetyl-hexapeptide-3-and-behenyl-alcohol)
- Keep them apart: [Acetyl hexapeptide-3 and isopropyl alcohol](https://lovi.care/skincare/sg/ingredients/acetyl-hexapeptide-3-and-isopropyl-alcohol)
- Keep them apart: [Acetyl hexapeptide-3 and polyvinyl alcohol](https://lovi.care/skincare/sg/ingredients/acetyl-hexapeptide-3-and-polyvinyl-alcohol)
- Keep them apart: [Copper and acetyl hexapeptide-3](https://lovi.care/skincare/sg/ingredients/copper-and-acetyl-hexapeptide-3)
- Keep them apart: [Magnesium and acetyl hexapeptide-3](https://lovi.care/skincare/sg/ingredients/magnesium-and-acetyl-hexapeptide-3)
- Keep them apart: [Acetyl hexapeptide-3 and zinc](https://lovi.care/skincare/sg/ingredients/acetyl-hexapeptide-3-and-zinc)
- Keep them apart: [Acetyl hexapeptide-3 and zinc sulfate](https://lovi.care/skincare/sg/ingredients/acetyl-hexapeptide-3-and-zinc-sulfate)
- Keep them apart: [Benzoyl peroxide and acetyl hexapeptide-3](https://lovi.care/skincare/sg/ingredients/benzoyl-peroxide-and-acetyl-hexapeptide-3)
- Keep them apart: [Azelaic acid and acetyl hexapeptide-3](https://lovi.care/skincare/sg/ingredients/azelaic-acid-and-acetyl-hexapeptide-3)
- Keep them apart: [Acetyl hexapeptide-3 and protease](https://lovi.care/skincare/sg/ingredients/acetyl-hexapeptide-3-and-protease)
- Keep them apart: [Acetyl hexapeptide-3 and superoxide dismutase](https://lovi.care/skincare/sg/ingredients/acetyl-hexapeptide-3-and-superoxide-dismutase)

## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi checks every pairing with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this pairing advice: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/ingredients/coenzyme-q10-and-acetyl-hexapeptide-3
- United Kingdom: https://lovi.care/skincare/uk/ingredients/coenzyme-q10-and-acetyl-hexapeptide-3
- Ireland: https://lovi.care/skincare/ie/ingredients/coenzyme-q10-and-acetyl-hexapeptide-3
- Germany: https://lovi.care/skincare/de/ingredients/coenzyme-q10-and-acetyl-hexapeptide-3
- France: https://lovi.care/skincare/fr/ingredients/coenzyme-q10-and-acetyl-hexapeptide-3
- Italy: https://lovi.care/skincare/it/ingredients/coenzyme-q10-and-acetyl-hexapeptide-3
- Netherlands: https://lovi.care/skincare/nl/ingredients/coenzyme-q10-and-acetyl-hexapeptide-3
- Spain: https://lovi.care/skincare/es/ingredients/coenzyme-q10-and-acetyl-hexapeptide-3
- Canada: https://lovi.care/skincare/ca/ingredients/coenzyme-q10-and-acetyl-hexapeptide-3
- Australia: https://lovi.care/skincare/au/ingredients/coenzyme-q10-and-acetyl-hexapeptide-3
- Singapore: https://lovi.care/skincare/sg/ingredients/coenzyme-q10-and-acetyl-hexapeptide-3 (this page)
- Saudi Arabia: https://lovi.care/skincare/sa/ingredients/coenzyme-q10-and-acetyl-hexapeptide-3
- United Arab Emirates: https://lovi.care/skincare/ae/ingredients/coenzyme-q10-and-acetyl-hexapeptide-3