# Citric acid and peptide-rich plasma

Page: https://lovi.care/skincare/sg/ingredients/citric-acid-and-peptide-rich-plasma

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Singapore.

Keep them apart

Apply the peptide [serum](https://lovi.care/skincare/sg/ingredients/serum) in the morning and the [citric acid](https://lovi.care/skincare/sg/ingredients/citric-acid) at night to prevent the acid from breaking down the peptides. Citric acid makes the skin too acidic, which ruins the firming power of peptides and makes them useless. You can use both if you space them out by several hours or switch to gentler products.

- [All about citric acid](https://lovi.care/skincare/sg/ingredients/citric-acid)
- [All about peptide-rich plasma](https://lovi.care/skincare/sg/ingredients/peptide-rich-plasma)

### [Citric acid](https://lovi.care/skincare/sg/ingredients/citric-acid) products

- [The Ordinary Salicylic Acid 2% Solution](https://lovi.care/skincare/sg/p/the-ordinary/salicylic-acid-2-solution/for/dry-skin) — Average fit
- [Dr. Bronner's Pure-Castile Liquid Soap (Baby Unscented)](https://lovi.care/skincare/sg/p/dr-bronner-s/pure-castile-liquid-soap-baby-unscented/for/dry-sensitive-skin) — Average fit
- [Thayers Hydrating Milky Toner](https://lovi.care/skincare/sg/p/thayers/hydrating-milky-toner/for/dry-skin) — High fit — [S$11.35 at Amazon](https://www.amazon.sg/dp/B0BS1RKKHW?tag=lovi-care-web-product0e-22&linkCode=osi&th=1&psc=1)
- [Seven Minerals Organic Aloe Vera Gel](https://lovi.care/skincare/sg/p/seven-minerals/organic-aloe-vera-gel/for/dry-sensitive-skin) — Average fit
- [SkinCeuticals Blemish + Age Defense](https://lovi.care/skincare/sg/p/skinceuticals/blemish-age-defense/for/oily-skin) — Superior fit
- [Naturie Hatomugi Skin Conditioner](https://lovi.care/skincare/sg/p/naturie/hatomugi-skin-conditioner/for/sensitive-skin) — High fit
- [E45 Cream](https://lovi.care/skincare/sg/p/e45/cream/for/dry-skin) — High fit — [S$89.33 at Amazon](https://www.amazon.sg/dp/B076GTPC43?tag=lovi-care-web-product0e-22&linkCode=osi&th=1&psc=1)
- [NATURIUM BHA Liquid Exfoliant 2%](https://lovi.care/skincare/sg/p/naturium/bha-liquid-exfoliant-2/for/oily-skin) — Superior fit — [S$31.03 at Amazon](https://www.amazon.sg/dp/B08881VH6J?tag=lovi-care-web-product0e-22&linkCode=osi&th=1&psc=1)
- [Dr. Sam's Flawless Cleanser](https://lovi.care/skincare/sg/p/dr-sam-s/flawless-cleanser/for/dry-skin) — High fit
- [Kiehl's Calendula Deep Cleansing Foaming Face Wash](https://lovi.care/skincare/sg/p/kiehl-s/calendula-deep-cleansing-foaming-face-wash/for/oily-skin) — Superior fit — [S$57.34 at YesStyle](https://www.yesstyle.com/en/kiehls-calendula-deep-cleansing-foaming-face-wash-230ml-230ml/info.html/pid.1117135920?curr=SGD&rco=SG)
- [Neutrogena Hydro Boost Micellar Water](https://lovi.care/skincare/sg/p/neutrogena/hydro-boost-micellar-water/for/dark-spots) — Average fit — [S$16.37 at Amazon](https://www.amazon.sg/dp/B0CLSZX63K?tag=lovi-care-web-product0e-22&linkCode=osi&th=1&psc=1)
- [Garnier SkinActive Blackhead Eliminating Scrub](https://lovi.care/skincare/sg/p/garnier-skinactive/blackhead-eliminating-scrub/for/oily-skin) — Low fit — [S$50.01 at Amazon](https://www.amazon.sg/dp/B00NVQC4YA?tag=lovi-care-web-product0e-22&linkCode=osi&th=1&psc=1)

### [Peptide-rich plasma](https://lovi.care/skincare/sg/ingredients/peptide-rich-plasma) products

- [Eighth Day Regenerative Serum](https://lovi.care/skincare/sg/p/eighth-day/regenerative-serum/for/dry-sensitive-skin) — High fit

## Questions and answers

### Can you use citric acid and peptide-rich plasma together?

No, you should keep [citric acid](https://lovi.care/skincare/sg/ingredients/citric-acid) and [peptide-rich plasma](https://lovi.care/skincare/sg/ingredients/peptide-rich-plasma) apart because the low pH of the acid destabilizes the peptides and reduces their activity. Use them in separate steps or routines, such as applying one in the morning and the other at night.

### Which goes first, citric acid or peptide-rich plasma?

Keep citric acid and peptide-rich plasma apart by using them in separate steps or routines, such as morning and evening separation. The acidic environment of citric acid may destabilize peptide bonds and reduce their bioactivity if combined.

### Are citric acid and peptide-rich plasma good for sensitive skin?

Citric acid and peptide-rich plasma are best kept apart in your routine, especially for sensitive skin, because the low pH of the acid may destabilize the peptide bonds and reduce their effectiveness. Use them in separate steps or routines instead.

## Research on citric acid and peptide-rich plasma

- [Clinical evaluation of the efficacy of a facial serum containing dioic acid, glycolic acid, salicylic acid, LHA, citric acid, and HEPES in treating post-inflammatory hyperchromia and controlling oily skin in patients with acne vulgaris](https://pubmed.ncbi.nlm.nih.gov/33617668/) Citric acid · Journal of Cosmetic Dermatology, 2021
- [Comparison of clindamycin 1% and benzoyl peroxide 5% gel to a novel composition containing salicylic acid, capryloyl salicylic acid, HEPES, glycolic acid, citric acid, and dioic acid in the treatment of acne vulgaris](https://pubmed.ncbi.nlm.nih.gov/23545907/) Citric acid · Journal of Drugs in Dermatology, 2013

## Other combinations

- Keep them apart: [Benzoyl peroxide and citric acid](https://lovi.care/skincare/sg/ingredients/benzoyl-peroxide-and-citric-acid)
- Keep them apart: [Retinol and citric acid](https://lovi.care/skincare/sg/ingredients/retinol-and-citric-acid)
- Depends on the strength: [Niacinamide and citric acid](https://lovi.care/skincare/sg/ingredients/niacinamide-and-citric-acid)
- Work well together: [Sodium lactate and citric acid](https://lovi.care/skincare/sg/ingredients/sodium-lactate-and-citric-acid)
- Work well together: [Citric acid and tromethamine](https://lovi.care/skincare/sg/ingredients/citric-acid-and-tromethamine)
- Keep them apart: [Adapalene and peptide-rich plasma](https://lovi.care/skincare/sg/ingredients/adapalene-and-peptide-rich-plasma)
- Keep them apart: [Granactive retinoid and peptide-rich plasma](https://lovi.care/skincare/sg/ingredients/granactive-retinoid-and-peptide-rich-plasma)
- Keep them apart: [Hydroxypinacolone retinoate and peptide-rich plasma](https://lovi.care/skincare/sg/ingredients/hydroxypinacolone-retinoate-and-peptide-rich-plasma)
- Keep them apart: [Pro-retinol and peptide-rich plasma](https://lovi.care/skincare/sg/ingredients/pro-retinol-and-peptide-rich-plasma)
- Keep them apart: [Retinal and peptide-rich plasma](https://lovi.care/skincare/sg/ingredients/retinal-and-peptide-rich-plasma)
- Keep them apart: [Retinoid blend and peptide-rich plasma](https://lovi.care/skincare/sg/ingredients/retinoid-blend-and-peptide-rich-plasma)
- Depends on the strength: [Retinol and peptide-rich plasma](https://lovi.care/skincare/sg/ingredients/retinol-and-peptide-rich-plasma)
- Keep them apart: [Tretinoin and peptide-rich plasma](https://lovi.care/skincare/sg/ingredients/tretinoin-and-peptide-rich-plasma)
- Keep them apart: [Vitamin A and peptide-rich plasma](https://lovi.care/skincare/sg/ingredients/vitamin-a-and-peptide-rich-plasma)
- Work well together: [Liposome and peptide-rich plasma](https://lovi.care/skincare/sg/ingredients/liposome-and-peptide-rich-plasma)
- Work well together: [Microcapsule and peptide-rich plasma](https://lovi.care/skincare/sg/ingredients/microcapsule-and-peptide-rich-plasma)
- Keep them apart: [Vitamin C and peptide-rich plasma](https://lovi.care/skincare/sg/ingredients/vitamin-c-and-peptide-rich-plasma)
- Work well together: [Betaine and peptide-rich plasma](https://lovi.care/skincare/sg/ingredients/betaine-and-peptide-rich-plasma)
- Work well together: [Glycerin and peptide-rich plasma](https://lovi.care/skincare/sg/ingredients/glycerin-and-peptide-rich-plasma)
- Work well together: [Hyaluronic acid and peptide-rich plasma](https://lovi.care/skincare/sg/ingredients/hyaluronic-acid-and-peptide-rich-plasma)
- Work well together: [Betaine and citric acid](https://lovi.care/skincare/sg/ingredients/betaine-and-citric-acid)
- Work well together: [Glycerin and citric acid](https://lovi.care/skincare/sg/ingredients/glycerin-and-citric-acid)
- Depends on the strength: [Hyaluronic acid and citric acid](https://lovi.care/skincare/sg/ingredients/hyaluronic-acid-and-citric-acid)
- Depends on the strength: [Niacinamide and peptide-rich plasma](https://lovi.care/skincare/sg/ingredients/niacinamide-and-peptide-rich-plasma)
- Work well together: [Panthenol and peptide-rich plasma](https://lovi.care/skincare/sg/ingredients/panthenol-and-peptide-rich-plasma)
- Work well together: [Bakuchiol and peptide-rich plasma](https://lovi.care/skincare/sg/ingredients/bakuchiol-and-peptide-rich-plasma)
- Work well together: [Arginine and peptide-rich plasma](https://lovi.care/skincare/sg/ingredients/arginine-and-peptide-rich-plasma)
- Work well together: [Peptide-rich plasma and GABA](https://lovi.care/skincare/sg/ingredients/peptide-rich-plasma-and-gaba)
- Work well together: [Silk amino acids and peptide-rich plasma](https://lovi.care/skincare/sg/ingredients/silk-amino-acids-and-peptide-rich-plasma)
- Work well together: [Taurine and peptide-rich plasma](https://lovi.care/skincare/sg/ingredients/taurine-and-peptide-rich-plasma)
- Work well together: [Peptide-rich plasma and theanine](https://lovi.care/skincare/sg/ingredients/peptide-rich-plasma-and-theanine)
- Keep them apart: [AHA blend glycolic and citric acids and peptide-rich plasma](https://lovi.care/skincare/sg/ingredients/aha-blend-glycolic-and-citric-acids-and-peptide-rich-plasma)
- Keep them apart: [Acetyl hexapeptide-3 and citric acid](https://lovi.care/skincare/sg/ingredients/acetyl-hexapeptide-3-and-citric-acid)
- Keep them apart: [Bio-placenta peptides and citric acid](https://lovi.care/skincare/sg/ingredients/bio-placenta-peptides-and-citric-acid)
- Keep them apart: [Carnosine and citric acid](https://lovi.care/skincare/sg/ingredients/carnosine-and-citric-acid)
- Keep them apart: [Collagen peptide and citric acid](https://lovi.care/skincare/sg/ingredients/collagen-peptide-and-citric-acid)
- Keep them apart: [Copper peptide and citric acid](https://lovi.care/skincare/sg/ingredients/copper-peptide-and-citric-acid)
- Keep them apart: [Hexapeptide and citric acid](https://lovi.care/skincare/sg/ingredients/hexapeptide-and-citric-acid)
- Keep them apart: [Citric acid and hexapeptide-9](https://lovi.care/skincare/sg/ingredients/citric-acid-and-hexapeptide-9)
- Keep them apart: [Citric acid and palmitoyl pentapeptide-4](https://lovi.care/skincare/sg/ingredients/citric-acid-and-palmitoyl-pentapeptide-4)
- Keep them apart: [Citric acid and palmitoyl tripeptide-1](https://lovi.care/skincare/sg/ingredients/citric-acid-and-palmitoyl-tripeptide-1)
- Keep them apart: [Citric acid and triple peptide blend](https://lovi.care/skincare/sg/ingredients/citric-acid-and-triple-peptide-blend)
- Keep them apart: [Glycolic acid and peptide-rich plasma](https://lovi.care/skincare/sg/ingredients/glycolic-acid-and-peptide-rich-plasma)
- Keep them apart: [Lactic acid and peptide-rich plasma](https://lovi.care/skincare/sg/ingredients/lactic-acid-and-peptide-rich-plasma)
- Keep them apart: [Mandelic acid and peptide-rich plasma](https://lovi.care/skincare/sg/ingredients/mandelic-acid-and-peptide-rich-plasma)
- Work well together: [Coenzyme Q10 and peptide-rich plasma](https://lovi.care/skincare/sg/ingredients/coenzyme-q10-and-peptide-rich-plasma)
- Work well together: [Green tea and peptide-rich plasma](https://lovi.care/skincare/sg/ingredients/green-tea-and-peptide-rich-plasma)
- Work well together: [Vitamin E and peptide-rich plasma](https://lovi.care/skincare/sg/ingredients/vitamin-e-and-peptide-rich-plasma)
- Keep them apart: [Adapalene and citric acid](https://lovi.care/skincare/sg/ingredients/adapalene-and-citric-acid)
- Keep them apart: [Granactive retinoid and citric acid](https://lovi.care/skincare/sg/ingredients/granactive-retinoid-and-citric-acid)
- Keep them apart: [Hydroxypinacolone retinoate and citric acid](https://lovi.care/skincare/sg/ingredients/hydroxypinacolone-retinoate-and-citric-acid)
- Keep them apart: [Pro-retinol and citric acid](https://lovi.care/skincare/sg/ingredients/pro-retinol-and-citric-acid)
- Keep them apart: [Retinal and citric acid](https://lovi.care/skincare/sg/ingredients/retinal-and-citric-acid)
- Keep them apart: [Retinoid blend and citric acid](https://lovi.care/skincare/sg/ingredients/retinoid-blend-and-citric-acid)
- Keep them apart: [Tretinoin and citric acid](https://lovi.care/skincare/sg/ingredients/tretinoin-and-citric-acid)
- Work well together: [Beta-sitosterol and peptide-rich plasma](https://lovi.care/skincare/sg/ingredients/beta-sitosterol-and-peptide-rich-plasma)
- Work well together: [Ceramide-building complex and peptide-rich plasma](https://lovi.care/skincare/sg/ingredients/ceramide-building-complex-and-peptide-rich-plasma)
- Work well together: [Cholesterol and peptide-rich plasma](https://lovi.care/skincare/sg/ingredients/cholesterol-and-peptide-rich-plasma)
- Work well together: [Phytosphingosine and peptide-rich plasma](https://lovi.care/skincare/sg/ingredients/phytosphingosine-and-peptide-rich-plasma)
- Work well together: [Phytosterol and peptide-rich plasma](https://lovi.care/skincare/sg/ingredients/phytosterol-and-peptide-rich-plasma)
- Work well together: [Peptide-rich plasma and squalene](https://lovi.care/skincare/sg/ingredients/peptide-rich-plasma-and-squalene)
- Work well together: [Peptide-rich plasma and tri-ceramide complex](https://lovi.care/skincare/sg/ingredients/peptide-rich-plasma-and-tri-ceramide-complex)
- Work well together: [Gluconolactone and citric acid](https://lovi.care/skincare/sg/ingredients/gluconolactone-and-citric-acid)
- Work well together: [Lactobionic acid and citric acid](https://lovi.care/skincare/sg/ingredients/lactobionic-acid-and-citric-acid)
- Keep them apart: [Salicylic acid and peptide-rich plasma](https://lovi.care/skincare/sg/ingredients/salicylic-acid-and-peptide-rich-plasma)
- Work well together: [Cholesterol and citric acid](https://lovi.care/skincare/sg/ingredients/cholesterol-and-citric-acid)
- Work well together: [Citric acid and lauric acid](https://lovi.care/skincare/sg/ingredients/citric-acid-and-lauric-acid)
- Work well together: [Linoleic acid and citric acid](https://lovi.care/skincare/sg/ingredients/linoleic-acid-and-citric-acid)
- Keep them apart: [Citric acid and tri-ceramide complex](https://lovi.care/skincare/sg/ingredients/citric-acid-and-tri-ceramide-complex)
- Work well together: [Arginine and citric acid](https://lovi.care/skincare/sg/ingredients/arginine-and-citric-acid)
- Work well together: [Citric acid and GABA](https://lovi.care/skincare/sg/ingredients/citric-acid-and-gaba)
- Work well together: [Silk amino acids and citric acid](https://lovi.care/skincare/sg/ingredients/silk-amino-acids-and-citric-acid)
- Work well together: [Taurine and citric acid](https://lovi.care/skincare/sg/ingredients/taurine-and-citric-acid)
- Work well together: [Citric acid and theanine](https://lovi.care/skincare/sg/ingredients/citric-acid-and-theanine)
- Keep them apart: [Peptide-rich plasma and baking soda](https://lovi.care/skincare/sg/ingredients/peptide-rich-plasma-and-baking-soda)
- Keep them apart: [Bleach and peptide-rich plasma](https://lovi.care/skincare/sg/ingredients/bleach-and-peptide-rich-plasma)
- Keep them apart: [Potassium hydroxide and peptide-rich plasma](https://lovi.care/skincare/sg/ingredients/potassium-hydroxide-and-peptide-rich-plasma)
- Keep them apart: [Peptide-rich plasma and behenyl alcohol](https://lovi.care/skincare/sg/ingredients/peptide-rich-plasma-and-behenyl-alcohol)
- Keep them apart: [Isopropyl alcohol and peptide-rich plasma](https://lovi.care/skincare/sg/ingredients/isopropyl-alcohol-and-peptide-rich-plasma)
- Keep them apart: [Polyvinyl alcohol and peptide-rich plasma](https://lovi.care/skincare/sg/ingredients/polyvinyl-alcohol-and-peptide-rich-plasma)
- Work well together: [Ferulic acid and citric acid](https://lovi.care/skincare/sg/ingredients/ferulic-acid-and-citric-acid)
- Work well together: [Vitamin E and citric acid](https://lovi.care/skincare/sg/ingredients/vitamin-e-and-citric-acid)
- Keep them apart: [Copper and peptide-rich plasma](https://lovi.care/skincare/sg/ingredients/copper-and-peptide-rich-plasma)
- Keep them apart: [Azelaic acid and citric acid](https://lovi.care/skincare/sg/ingredients/azelaic-acid-and-citric-acid)
- Keep them apart: [Salicylic acid and citric acid](https://lovi.care/skincare/sg/ingredients/salicylic-acid-and-citric-acid)
- Work well together: [Allantoin and citric acid](https://lovi.care/skincare/sg/ingredients/allantoin-and-citric-acid)
- Work well together: [Citric acid and bisabolol](https://lovi.care/skincare/sg/ingredients/citric-acid-and-bisabolol)
- Work well together: [Panthenol and citric acid](https://lovi.care/skincare/sg/ingredients/panthenol-and-citric-acid)
- Keep them apart: [Magnesium and peptide-rich plasma](https://lovi.care/skincare/sg/ingredients/magnesium-and-peptide-rich-plasma)
- Keep them apart: [Zinc and peptide-rich plasma](https://lovi.care/skincare/sg/ingredients/zinc-and-peptide-rich-plasma)
- Keep them apart: [Zinc sulfate and peptide-rich plasma](https://lovi.care/skincare/sg/ingredients/zinc-sulfate-and-peptide-rich-plasma)
- Keep them apart: [Benzoyl peroxide and peptide-rich plasma](https://lovi.care/skincare/sg/ingredients/benzoyl-peroxide-and-peptide-rich-plasma)
- Keep them apart: [Azelaic acid and peptide-rich plasma](https://lovi.care/skincare/sg/ingredients/azelaic-acid-and-peptide-rich-plasma)
- Keep them apart: [Peptide-rich plasma and protease](https://lovi.care/skincare/sg/ingredients/peptide-rich-plasma-and-protease)
- Keep them apart: [Superoxide dismutase and peptide-rich plasma](https://lovi.care/skincare/sg/ingredients/superoxide-dismutase-and-peptide-rich-plasma)

## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi checks every pairing with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this pairing advice: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/ingredients/citric-acid-and-peptide-rich-plasma
- United Kingdom: https://lovi.care/skincare/uk/ingredients/citric-acid-and-peptide-rich-plasma
- Ireland: https://lovi.care/skincare/ie/ingredients/citric-acid-and-peptide-rich-plasma
- Germany: https://lovi.care/skincare/de/ingredients/citric-acid-and-peptide-rich-plasma
- France: https://lovi.care/skincare/fr/ingredients/citric-acid-and-peptide-rich-plasma
- Italy: https://lovi.care/skincare/it/ingredients/citric-acid-and-peptide-rich-plasma
- Netherlands: https://lovi.care/skincare/nl/ingredients/citric-acid-and-peptide-rich-plasma
- Spain: https://lovi.care/skincare/es/ingredients/citric-acid-and-peptide-rich-plasma
- Canada: https://lovi.care/skincare/ca/ingredients/citric-acid-and-peptide-rich-plasma
- Australia: https://lovi.care/skincare/au/ingredients/citric-acid-and-peptide-rich-plasma
- Singapore: https://lovi.care/skincare/sg/ingredients/citric-acid-and-peptide-rich-plasma (this page)
- Saudi Arabia: https://lovi.care/skincare/sa/ingredients/citric-acid-and-peptide-rich-plasma
- United Arab Emirates: https://lovi.care/skincare/ae/ingredients/citric-acid-and-peptide-rich-plasma