# Benzoyl peroxide and hexapeptide-9

Page: https://lovi.care/skincare/sg/ingredients/benzoyl-peroxide-and-hexapeptide-9

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Singapore.

Keep them apart

Use them at different times of day, with [benzoyl peroxide](https://lovi.care/skincare/sg/ingredients/benzoyl-peroxide) in the morning and [hexapeptide-9](https://lovi.care/skincare/sg/ingredients/hexapeptide-9) at night, because they cancel each other out. Benzoyl peroxide can break down and weaken the helpful anti-aging effects of the peptide. You can use them safely by applying them in separate routines.

- [All about benzoyl peroxide](https://lovi.care/skincare/sg/ingredients/benzoyl-peroxide)
- [All about hexapeptide-9](https://lovi.care/skincare/sg/ingredients/hexapeptide-9)

### [Benzoyl peroxide](https://lovi.care/skincare/sg/ingredients/benzoyl-peroxide) products

- [Proactiv Renewing Cleanser](https://lovi.care/skincare/sg/p/proactiv/renewing-cleanser/for/oily-acne-prone-skin) — Average fit — [S$34.99 at Amazon](https://www.amazon.sg/dp/B004DOYM2Q?tag=lovi-care-web-product0e-22&linkCode=osi&th=1&psc=1)
- [Clean & Clear Persa-Gel 10](https://lovi.care/skincare/sg/p/clean-and-clear/persa-gel-10/for/oily-acne-prone-skin) — Superior fit — [S$25.46 at Amazon](https://www.amazon.sg/dp/B00E4MM8N2?tag=lovi-care-web-product0e-22&linkCode=osi&th=1&psc=1)
- [Differin Daily Deep Cleanser](https://lovi.care/skincare/sg/p/differin/daily-deep-cleanser/for/oily-acne-prone-skin) — Average fit
- [Neutrogena Clear Pore Cleanser/Mask](https://lovi.care/skincare/sg/p/neutrogena/clear-pore-cleanser-mask/for/acne-prone-skin) — High fit
- [Proactiv Repairing Treatment](https://lovi.care/skincare/sg/p/proactiv/repairing-treatment/for/oily-skin) — High fit
- [Paula's Choice Clear Daily Skin Clearing Treatment](https://lovi.care/skincare/sg/p/paula-s-choice/clear-daily-skin-clearing-treatment/for/acne-prone-skin) — Average fit
- [Galderma Epiduo Gel](https://lovi.care/skincare/sg/p/galderma/epiduo-gel/for/acne-prone-skin) — High fit
- [Galderma Benzac AC 5](https://lovi.care/skincare/sg/p/galderma/benzac-ac-5/for/oily-acne-prone-skin) — High fit
- [CeraVe Acne Foaming Cream Cleanser](https://lovi.care/skincare/sg/p/cerave/acne-foaming-cream-cleanser/for/oily-skin) — High fit
- [Galderma Benzac AC Mild Strength 2.5% Acne Gel](https://lovi.care/skincare/sg/p/galderma/benzac-ac-mild-strength-2-5-acne-gel/for/oily-acne-prone-skin) — High fit
- [PanOxyl Acne Foaming Wash](https://lovi.care/skincare/sg/p/panoxyl/acne-foaming-wash/for/oily-acne-prone-skin) — High fit
- [PanOxyl Acne Creamy Wash](https://lovi.care/skincare/sg/p/panoxyl/acne-creamy-wash/for/oily-acne-prone-skin) — Average fit

### [Hexapeptide-9](https://lovi.care/skincare/sg/ingredients/hexapeptide-9) products

- [Elemis Pro-Collagen Night Cream](https://lovi.care/skincare/sg/p/elemis/pro-collagen-night-cream/for/dry-sensitive-skin) — Superior fit
- [Murad Cellular Hydration Repair Serum](https://lovi.care/skincare/sg/p/murad/cellular-hydration-repair-serum/for/acne-prone-skin) — High fit
- [MARY & MAY 6 Peptide Complex Serum](https://lovi.care/skincare/sg/p/mary-and-may/6-peptide-complex-serum/for/mature-skin) — High fit — [S$11.96 at YesStyle](https://www.yesstyle.com/en/mary-may-6-peptide-complex-serum-30ml/info.html/pid.1100063350?curr=SGD&rco=SG)

## Questions and answers

### Can you use benzoyl peroxide and hexapeptide-9 together?

No, you should keep [benzoyl peroxide](https://lovi.care/skincare/sg/ingredients/benzoyl-peroxide) and [hexapeptide-9](https://lovi.care/skincare/sg/ingredients/hexapeptide-9) apart because benzoyl peroxide oxidizes peptide bonds and reduces their efficacy. Instead, use your hexapeptide-9 products separately in your PM routine.

### Which goes first, benzoyl peroxide or hexapeptide-9?

Keep benzoyl peroxide and hexapeptide-9 apart because benzoyl peroxide oxidizes peptide bonds and reduces efficacy, so use hexapeptide-9 separately in your PM routine.

### Are benzoyl peroxide and hexapeptide-9 good for sensitive skin?

No, you should keep benzoyl peroxide and hexapeptide-9 apart because benzoyl peroxide oxidizes peptide bonds and reduces efficacy, so use hexapeptide-9 separately in your PM routine.

## Research on benzoyl peroxide and hexapeptide-9

- [Topical benzoyl peroxide for acne](https://pubmed.ncbi.nlm.nih.gov/32175593/) Benzoyl peroxide · The Cochrane Database of Systematic Reviews, 2020
- [Benzoyl peroxide treatment decreases Cutibacterium acnes in shoulder surgery, from skin incision until wound closure](https://pubmed.ncbi.nlm.nih.gov/33545336/) Benzoyl peroxide · Journal of Shoulder and Elbow Surgery, 2021
- [Efficacy and Safety of a Fixed-Dose Clindamycin Phosphate 1.2%, Benzoyl Peroxide 3.1%, and Adapalene 0.15% Gel for Moderate-to-Severe Acne: A Randomized Phase II Study of the First Triple-Combination Drug](https://pubmed.ncbi.nlm.nih.gov/34674160/) Benzoyl peroxide · American Journal of Clinical Dermatology, 2022
- [Novel Cyclized Hexapeptide-9 Outperforms Retinol Against Skin Aging: A Randomized, Double-Blinded, Active- and Vehicle-Controlled Clinical Trial](https://pubmed.ncbi.nlm.nih.gov/40586182/) Hexapeptide-9 · Journal of Cosmetic Dermatology, 2025

## Other combinations

- Keep them apart: [Benzoyl peroxide and aha blend glycolic and citric acids](https://lovi.care/skincare/sg/ingredients/benzoyl-peroxide-and-aha-blend-glycolic-and-citric-acids)
- Keep them apart: [Benzoyl peroxide and citric acid](https://lovi.care/skincare/sg/ingredients/benzoyl-peroxide-and-citric-acid)
- Keep them apart: [Glycolic acid and benzoyl peroxide](https://lovi.care/skincare/sg/ingredients/glycolic-acid-and-benzoyl-peroxide)
- Keep them apart: [Benzoyl peroxide and lactic acid](https://lovi.care/skincare/sg/ingredients/benzoyl-peroxide-and-lactic-acid)
- Keep them apart: [Benzoyl peroxide and mandelic acid](https://lovi.care/skincare/sg/ingredients/benzoyl-peroxide-and-mandelic-acid)
- Keep them apart: [Benzoyl peroxide and salicylic acid](https://lovi.care/skincare/sg/ingredients/benzoyl-peroxide-and-salicylic-acid)
- Work well together: [Benzoyl peroxide and ceramide-building complex](https://lovi.care/skincare/sg/ingredients/benzoyl-peroxide-and-ceramide-building-complex)
- Work well together: [Benzoyl peroxide and tri-ceramide complex](https://lovi.care/skincare/sg/ingredients/benzoyl-peroxide-and-tri-ceramide-complex)
- Keep them apart: [Adapalene and hexapeptide-9](https://lovi.care/skincare/sg/ingredients/adapalene-and-hexapeptide-9)
- Keep them apart: [Granactive retinoid and hexapeptide-9](https://lovi.care/skincare/sg/ingredients/granactive-retinoid-and-hexapeptide-9)
- Keep them apart: [Hydroxypinacolone retinoate and hexapeptide-9](https://lovi.care/skincare/sg/ingredients/hydroxypinacolone-retinoate-and-hexapeptide-9)
- Keep them apart: [Pro-retinol and hexapeptide-9](https://lovi.care/skincare/sg/ingredients/pro-retinol-and-hexapeptide-9)
- Keep them apart: [Retinal and hexapeptide-9](https://lovi.care/skincare/sg/ingredients/retinal-and-hexapeptide-9)
- Keep them apart: [Retinoid blend and hexapeptide-9](https://lovi.care/skincare/sg/ingredients/retinoid-blend-and-hexapeptide-9)
- Depends on the strength: [Retinol and hexapeptide-9](https://lovi.care/skincare/sg/ingredients/retinol-and-hexapeptide-9)
- Keep them apart: [Tretinoin and hexapeptide-9](https://lovi.care/skincare/sg/ingredients/tretinoin-and-hexapeptide-9)
- Keep them apart: [Vitamin A and hexapeptide-9](https://lovi.care/skincare/sg/ingredients/vitamin-a-and-hexapeptide-9)
- Work well together: [Liposome and hexapeptide-9](https://lovi.care/skincare/sg/ingredients/liposome-and-hexapeptide-9)
- Work well together: [Microcapsule and hexapeptide-9](https://lovi.care/skincare/sg/ingredients/microcapsule-and-hexapeptide-9)
- Depends on the strength: [Vitamin C and hexapeptide-9](https://lovi.care/skincare/sg/ingredients/vitamin-c-and-hexapeptide-9)
- Work well together: [Betaine and hexapeptide-9](https://lovi.care/skincare/sg/ingredients/betaine-and-hexapeptide-9)
- Work well together: [Glycerin and hexapeptide-9](https://lovi.care/skincare/sg/ingredients/glycerin-and-hexapeptide-9)
- Work well together: [Hyaluronic acid and hexapeptide-9](https://lovi.care/skincare/sg/ingredients/hyaluronic-acid-and-hexapeptide-9)
- Depends on the strength: [Niacinamide and hexapeptide-9](https://lovi.care/skincare/sg/ingredients/niacinamide-and-hexapeptide-9)
- Work well together: [Panthenol and hexapeptide-9](https://lovi.care/skincare/sg/ingredients/panthenol-and-hexapeptide-9)
- Work well together: [Bakuchiol and hexapeptide-9](https://lovi.care/skincare/sg/ingredients/bakuchiol-and-hexapeptide-9)
- Keep them apart: [Benzoyl peroxide and vitamin C](https://lovi.care/skincare/sg/ingredients/benzoyl-peroxide-and-vitamin-c)
- Work well together: [Arginine and hexapeptide-9](https://lovi.care/skincare/sg/ingredients/arginine-and-hexapeptide-9)
- Work well together: [Hexapeptide-9 and GABA](https://lovi.care/skincare/sg/ingredients/hexapeptide-9-and-gaba)
- Work well together: [Silk amino acids and hexapeptide-9](https://lovi.care/skincare/sg/ingredients/silk-amino-acids-and-hexapeptide-9)
- Work well together: [Taurine and hexapeptide-9](https://lovi.care/skincare/sg/ingredients/taurine-and-hexapeptide-9)
- Work well together: [Hexapeptide-9 and theanine](https://lovi.care/skincare/sg/ingredients/hexapeptide-9-and-theanine)
- Keep them apart: [AHA blend glycolic and citric acids and hexapeptide-9](https://lovi.care/skincare/sg/ingredients/aha-blend-glycolic-and-citric-acids-and-hexapeptide-9)
- Keep them apart: [Citric acid and hexapeptide-9](https://lovi.care/skincare/sg/ingredients/citric-acid-and-hexapeptide-9)
- Keep them apart: [Glycolic acid and hexapeptide-9](https://lovi.care/skincare/sg/ingredients/glycolic-acid-and-hexapeptide-9)
- Keep them apart: [Lactic acid and hexapeptide-9](https://lovi.care/skincare/sg/ingredients/lactic-acid-and-hexapeptide-9)
- Keep them apart: [Mandelic acid and hexapeptide-9](https://lovi.care/skincare/sg/ingredients/mandelic-acid-and-hexapeptide-9)
- Work well together: [Coenzyme Q10 and hexapeptide-9](https://lovi.care/skincare/sg/ingredients/coenzyme-q10-and-hexapeptide-9)
- Work well together: [Green tea and hexapeptide-9](https://lovi.care/skincare/sg/ingredients/green-tea-and-hexapeptide-9)
- Work well together: [Vitamin E and hexapeptide-9](https://lovi.care/skincare/sg/ingredients/vitamin-e-and-hexapeptide-9)
- Work well together: [Hexapeptide-9 and beta-sitosterol](https://lovi.care/skincare/sg/ingredients/hexapeptide-9-and-beta-sitosterol)
- Work well together: [Ceramide-building complex and hexapeptide-9](https://lovi.care/skincare/sg/ingredients/ceramide-building-complex-and-hexapeptide-9)
- Work well together: [Cholesterol and hexapeptide-9](https://lovi.care/skincare/sg/ingredients/cholesterol-and-hexapeptide-9)
- Work well together: [Phytosphingosine and hexapeptide-9](https://lovi.care/skincare/sg/ingredients/phytosphingosine-and-hexapeptide-9)
- Work well together: [Phytosterol and hexapeptide-9](https://lovi.care/skincare/sg/ingredients/phytosterol-and-hexapeptide-9)
- Work well together: [Hexapeptide-9 and squalene](https://lovi.care/skincare/sg/ingredients/hexapeptide-9-and-squalene)
- Work well together: [Hexapeptide-9 and tri-ceramide complex](https://lovi.care/skincare/sg/ingredients/hexapeptide-9-and-tri-ceramide-complex)
- Keep them apart: [Salicylic acid and hexapeptide-9](https://lovi.care/skincare/sg/ingredients/salicylic-acid-and-hexapeptide-9)
- Keep them apart: [Hexapeptide-9 and baking soda](https://lovi.care/skincare/sg/ingredients/hexapeptide-9-and-baking-soda)
- Keep them apart: [Bleach and hexapeptide-9](https://lovi.care/skincare/sg/ingredients/bleach-and-hexapeptide-9)
- Keep them apart: [Potassium hydroxide and hexapeptide-9](https://lovi.care/skincare/sg/ingredients/potassium-hydroxide-and-hexapeptide-9)
- Keep them apart: [Hexapeptide-9 and behenyl alcohol](https://lovi.care/skincare/sg/ingredients/hexapeptide-9-and-behenyl-alcohol)
- Keep them apart: [Hexapeptide-9 and isopropyl alcohol](https://lovi.care/skincare/sg/ingredients/hexapeptide-9-and-isopropyl-alcohol)
- Keep them apart: [Polyvinyl alcohol and hexapeptide-9](https://lovi.care/skincare/sg/ingredients/polyvinyl-alcohol-and-hexapeptide-9)
- Work well together: [Benzoyl peroxide and niacinamide](https://lovi.care/skincare/sg/ingredients/benzoyl-peroxide-and-niacinamide)
- Keep them apart: [Copper and hexapeptide-9](https://lovi.care/skincare/sg/ingredients/copper-and-hexapeptide-9)
- Keep them apart: [Adapalene and benzoyl peroxide](https://lovi.care/skincare/sg/ingredients/adapalene-and-benzoyl-peroxide)
- Keep them apart: [Benzoyl peroxide and granactive retinoid](https://lovi.care/skincare/sg/ingredients/benzoyl-peroxide-and-granactive-retinoid)
- Keep them apart: [Benzoyl peroxide and hydroxypinacolone retinoate](https://lovi.care/skincare/sg/ingredients/benzoyl-peroxide-and-hydroxypinacolone-retinoate)
- Keep them apart: [Benzoyl peroxide and pro-retinol](https://lovi.care/skincare/sg/ingredients/benzoyl-peroxide-and-pro-retinol)
- Keep them apart: [Benzoyl peroxide and retinal](https://lovi.care/skincare/sg/ingredients/benzoyl-peroxide-and-retinal)
- Keep them apart: [Benzoyl peroxide and retinoid blend](https://lovi.care/skincare/sg/ingredients/benzoyl-peroxide-and-retinoid-blend)
- Keep them apart: [Benzoyl peroxide and retinol](https://lovi.care/skincare/sg/ingredients/benzoyl-peroxide-and-retinol)
- Keep them apart: [Benzoyl peroxide and tretinoin](https://lovi.care/skincare/sg/ingredients/benzoyl-peroxide-and-tretinoin)
- Keep them apart: [Benzoyl peroxide and copper peptide](https://lovi.care/skincare/sg/ingredients/benzoyl-peroxide-and-copper-peptide)
- Keep them apart: [Benzoyl peroxide and palmitoyl pentapeptide-4](https://lovi.care/skincare/sg/ingredients/benzoyl-peroxide-and-palmitoyl-pentapeptide-4)
- Keep them apart: [Benzoyl peroxide and palmitoyl tripeptide-1](https://lovi.care/skincare/sg/ingredients/benzoyl-peroxide-and-palmitoyl-tripeptide-1)
- Keep them apart: [Magnesium and hexapeptide-9](https://lovi.care/skincare/sg/ingredients/magnesium-and-hexapeptide-9)
- Keep them apart: [Zinc and hexapeptide-9](https://lovi.care/skincare/sg/ingredients/zinc-and-hexapeptide-9)
- Keep them apart: [Zinc sulfate and hexapeptide-9](https://lovi.care/skincare/sg/ingredients/zinc-sulfate-and-hexapeptide-9)
- Work well together: [Benzoyl peroxide and zinc](https://lovi.care/skincare/sg/ingredients/benzoyl-peroxide-and-zinc)
- Work well together: [Benzoyl peroxide and zinc gluconate](https://lovi.care/skincare/sg/ingredients/benzoyl-peroxide-and-zinc-gluconate)
- Work well together: [Benzoyl peroxide and zinc oxide](https://lovi.care/skincare/sg/ingredients/benzoyl-peroxide-and-zinc-oxide)
- Work well together: [Benzoyl peroxide and zinc sulfate](https://lovi.care/skincare/sg/ingredients/benzoyl-peroxide-and-zinc-sulfate)
- Keep them apart: [Benzoyl peroxide and acetyl hexapeptide-3](https://lovi.care/skincare/sg/ingredients/benzoyl-peroxide-and-acetyl-hexapeptide-3)
- Keep them apart: [Benzoyl peroxide and bio-placenta peptides](https://lovi.care/skincare/sg/ingredients/benzoyl-peroxide-and-bio-placenta-peptides)
- Keep them apart: [Benzoyl peroxide and collagen peptide](https://lovi.care/skincare/sg/ingredients/benzoyl-peroxide-and-collagen-peptide)
- Keep them apart: [Benzoyl peroxide and hexapeptide](https://lovi.care/skincare/sg/ingredients/benzoyl-peroxide-and-hexapeptide)
- Keep them apart: [Benzoyl peroxide and peptide-rich plasma](https://lovi.care/skincare/sg/ingredients/benzoyl-peroxide-and-peptide-rich-plasma)
- Keep them apart: [Benzoyl peroxide and triple peptide blend](https://lovi.care/skincare/sg/ingredients/benzoyl-peroxide-and-triple-peptide-blend)
- Keep them apart: [Benzoyl peroxide and isopropyl alcohol](https://lovi.care/skincare/sg/ingredients/benzoyl-peroxide-and-isopropyl-alcohol)
- Keep them apart: [Benzoyl peroxide and sodium lauryl sulfate](https://lovi.care/skincare/sg/ingredients/benzoyl-peroxide-and-sodium-lauryl-sulfate)
- Keep them apart: [Azelaic acid and hexapeptide-9](https://lovi.care/skincare/sg/ingredients/azelaic-acid-and-hexapeptide-9)
- Keep them apart: [Hexapeptide-9 and protease](https://lovi.care/skincare/sg/ingredients/hexapeptide-9-and-protease)
- Keep them apart: [Superoxide dismutase and hexapeptide-9](https://lovi.care/skincare/sg/ingredients/superoxide-dismutase-and-hexapeptide-9)

## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi checks every pairing with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this pairing advice: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/ingredients/benzoyl-peroxide-and-hexapeptide-9
- United Kingdom: https://lovi.care/skincare/uk/ingredients/benzoyl-peroxide-and-hexapeptide-9
- Ireland: https://lovi.care/skincare/ie/ingredients/benzoyl-peroxide-and-hexapeptide-9
- Germany: https://lovi.care/skincare/de/ingredients/benzoyl-peroxide-and-hexapeptide-9
- France: https://lovi.care/skincare/fr/ingredients/benzoyl-peroxide-and-hexapeptide-9
- Italy: https://lovi.care/skincare/it/ingredients/benzoyl-peroxide-and-hexapeptide-9
- Netherlands: https://lovi.care/skincare/nl/ingredients/benzoyl-peroxide-and-hexapeptide-9
- Spain: https://lovi.care/skincare/es/ingredients/benzoyl-peroxide-and-hexapeptide-9
- Canada: https://lovi.care/skincare/ca/ingredients/benzoyl-peroxide-and-hexapeptide-9
- Australia: https://lovi.care/skincare/au/ingredients/benzoyl-peroxide-and-hexapeptide-9
- Singapore: https://lovi.care/skincare/sg/ingredients/benzoyl-peroxide-and-hexapeptide-9 (this page)
- Saudi Arabia: https://lovi.care/skincare/sa/ingredients/benzoyl-peroxide-and-hexapeptide-9
- United Arab Emirates: https://lovi.care/skincare/ae/ingredients/benzoyl-peroxide-and-hexapeptide-9