# Skintific vs Natura Bissé

Page: https://lovi.care/skincare/sg/compare/skintific-vs-natura-bisse

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Singapore.

Skintific and Natura Bissé are distinct skincare lines, with the former loved for its moisturizers, [serums](https://lovi.care/skincare/sg/ingredients/serum), and sunscreens utilizing carefully formulated ingredients, and the latter known as a Spanish brand founded in 1979 and owned by Natura Bissé International, S.A. for its luxurious moisturizers and advanced formulas. While the first brand suits oily, acne-prone, and combination skin best due to these targeted formulations, the second suits mature, dry, and sensitive skin best due to their rich nourishing properties. Through these offerings, both deliver effective daily care to restore balance and vitality to the complexion.

Natura Bissé is a Spanish skincare brand founded in 1979 and owned by Natura Bissé International, S.A..

[naturabisse.com](https://www.naturabisse.com/int/en/our-story.html) [tracxn.com](https://tracxn.com/d/accelerator-incubator/ushopal/__yjGH7DKhQGNWnINKarEuFce6tilrPzGJv0PnASFLfpg)

This page compares some of the most popular Skintific and Natura Bissé products; for every product of both brands, with a fit score for your own skin, [use the Lovi app](https://app.pora.ai/vqqJ/j1xj2b6o?af_sub2=compare&af_sub3=selection_note&af_sub4=pgaf0f73240d).

### Popular Skintific vs Natura Bissé products

#### Natura Bissé

- [Diamond Extreme](https://lovi.care/skincare/sg/p/natura-bisse/diamond-extreme/for/mature-skin) — Superior fit — [S$379.15 at Amazon](https://www.amazon.sg/dp/B0032YV8RU?tag=lovi-care-web-product0e-22&linkCode=osi&th=1&psc=1)

#### Skintific

- [5X Ceramide Barrier Moisture Gel](https://lovi.care/skincare/sg/p/skintific/5x-ceramide-barrier-moisture-gel/for/dry-sensitive-skin) — High fit — [S$17.22 at YesStyle](https://www.yesstyle.com/en/skintific-5x-ceramide-barrier-moisture-gel-30g/info.html/pid.1136489178?curr=SGD&rco=SG)
- [MUGWORT](https://lovi.care/skincare/sg/p/skintific/mugwort/for/dry-skin) — Average fit — [S$13.39 at YesStyle](https://www.yesstyle.com/en/skintific-mugwort-acne-clay-stick-40g/info.html/pid.1136489187?curr=SGD&rco=SG)
- [All Day Light Sunscreen Mist](https://lovi.care/skincare/sg/p/skintific/all-day-light-sunscreen-mist/for/dark-spots) — High fit
- [AHA BHA PHA LHA Peeling Solution](https://lovi.care/skincare/sg/p/skintific/aha-bha-pha-lha-peeling-solution/for/oily-acne-prone-skin) — High fit — [S$19.53 at YesStyle](https://www.yesstyle.com/en/skintific-12-aha-bha-pha-lha-peeling-solution-30ml/info.html/pid.1136493068?curr=SGD&rco=SG)
- [MATE FIT](https://lovi.care/skincare/sg/p/skintific/mate-fit/for/oily-acne-prone-skin) — High fit — [S$16.34 at YesStyle](https://www.yesstyle.com/en/skintific-matte-fit-serum-sunscreen-spf50-pa-50g/info.html/pid.1136493008?curr=SGD&rco=SG)

## Questions and answers

### Skintific or Natura Bissé: which is better?

Skintific and Natura Bissé serve different needs, with Skintific offering fragrance-free options that Lovi rates High for oily and combination skin, while Natura Bissé provides Diamond Extreme, which Lovi rates Superior for mature skin.

### What is the difference between Skintific and Natura Bissé?

Skintific is a newer brand founded in 2021 with fragrance-free products on this page, whereas Natura Bissé was founded in 1979 in Spain and includes fragrance in its Diamond Extreme moisturizer. Skintific fits oily acne-prone, combination, and oily skin best, while Natura Bissé has a superior fit for mature skin with its Diamond Extreme cream.

### Skintific or Natura Bissé: which moisturizer is better?

For mature skin, Natura Bissé Diamond Extreme achieves a Superior Lovi fit level, whereas Skintific 5X Ceramide Barrier Moisture Gel achieves an Average fit level. Natura Bissé Diamond Extreme also contains fragrance, while Skintific products on this page list no fragrance.

### Which is more affordable, Skintific or Natura Bissé?

The provided page facts do not contain pricing information for either Skintific or Natura Bissé, so affordability cannot be determined.

### Which causes fewer breakouts, Skintific or Natura Bissé?

Skintific is better for oily and acne-prone skin types, whereas Natura Bissé's Diamond Extreme is rated Average for acne-prone skin. Lovi gives Skintific's products high fit ratings for acne-prone skin on this page, including the 5X Ceramide Barrier Moisture Gel and All Day Light Sunscreen Mist.

### How do the founding years and company ownership compare between Skintific and Natura Bissé?

Skintific was founded in 2021 and is owned by Guangzhou Feimei Network Technology Co., Ltd., whereas Natura Bissé was founded in 1979 in Spain and is owned by Natura Bissé International, S.A.

### Which of the two brands offers products that are completely free of fragrance according to their ingredient lists?

Skintific offers products that are completely free of fragrance, as every product on this page lists no fragrance in its ingredients, whereas Natura Bissé includes fragrance in its Diamond Extreme product.

### How does the Lovi fit level for dry skin differ between Skintific's 5X Ceramide Barrier Moisture Gel and Natura Bissé's Diamond Extreme?

For dry skin, Lovi rates Skintific's 5X Ceramide Barrier Moisture Gel as High, whereas Natura Bissé's Diamond Extreme is also rated as High.

## Research behind their key ingredients

- [Benefits of topical hyaluronic acid for skin quality and signs of skin aging: From literature review to clinical evidence](https://pubmed.ncbi.nlm.nih.gov/36200921/) Hyaluronic acid · Dermatologic Therapy, 2022
- [Topical use of dexpanthenol in skin disorders](https://pubmed.ncbi.nlm.nih.gov/12113650/) Panthenol · American Journal of Clinical Dermatology, 2002
- [Moisturizing and Antiinflammatory Properties of Cosmetic Formulations Containing Centella asiatica Extract](https://pubmed.ncbi.nlm.nih.gov/27168678/) Centella asiatica extract · Indian Journal of Pharmaceutical Sciences, 2016
- [Topical Application of Centella asiatica in Wound Healing: Recent Insights into Mechanisms and Clinical Efficacy](https://pubmed.ncbi.nlm.nih.gov/39458583/) Centella asiatica extract · Pharmaceutics, 2024
- [Alteration of barrier properties, stratum corneum ceramides and microbiome composition in response to lotion application on cosmetic dry skin](https://pubmed.ncbi.nlm.nih.gov/35340018/) Ceramide · Scientific Reports, 2022
- [Ceramide 1 and ceramide 3 act synergistically on skin hydration and the transepidermal water loss of sodium lauryl sulfate-irritated skin](https://pubmed.ncbi.nlm.nih.gov/18717861/) Ceramide np, Ceramide eop · International Journal of Dermatology, 2008
- [The 24-hour skin hydration and barrier function effects of a hyaluronic 1%, glycerin 5%, and Centella asiatica stem cells extract moisturizing fluid: an intra-subject, randomized, assessor-blinded study](https://pubmed.ncbi.nlm.nih.gov/28860834/) Glycerin · Clinical, Cosmetic and Investigational Dermatology, 2017
- [Anti-Aging Effects of Leontopodium alpinum (Edelweiss) Callus Culture Extract Through Transcriptome Profiling](https://pubmed.ncbi.nlm.nih.gov/32098197/) Leontopodium alpinum leaf extract flower · Genes, 2020
- [Anti-inflammatory effects of concentrated ethanol extracts of Edelweiss (Leontopodium alpinum Cass.) callus cultures towards human keratinocytes and endothelial cells](https://pubmed.ncbi.nlm.nih.gov/23093820/) Leontopodium alpinum leaf extract flower · Mediators of Inflammation, 2012
- [A new topical panthenol-containing emollient: Results from two randomized controlled studies assessing its skin moisturization and barrier restoration potential, and the effect on skin microflora](https://pubmed.ncbi.nlm.nih.gov/27425824/) Panthenol · The Journal of Dermatological Treatment, 2017
- [A Double-Blinded, Randomized, Vehicle-Controlled Study of the Efficacy of Moisturizer Containing Licochalcone A, Decanediol, L-Carnitine, and Salicylic Acid for Prevention of Acne Relapse in Asian Population](https://pubmed.ncbi.nlm.nih.gov/33150170/) Salicylic acid · BioMed Research International, 2020
- [Microneedling by dermapen and glycolic acid peel for the treatment of acne scars: Comparative study](https://pubmed.ncbi.nlm.nih.gov/30548170/) Glycolic acid · Journal of Cosmetic Dermatology, 2019
- [High molecular compounds (polysaccharides and proanthocyanidins) from Hamamelis virginiana bark: influence on human skin keratinocyte proliferation and differentiation and influence on irritated skin](https://pubmed.ncbi.nlm.nih.gov/11684194/) Witch hazel extract · Phytochemistry, 2001
- [Efficacy of a topical gel containing chitosan, chlorhexidine, allantoin and dexpanthenol for pain and inflammation control after third molar surgery: A randomized and placebo-controlled clinical trial](https://pubmed.ncbi.nlm.nih.gov/32683390/) Allantoin · Medicina Oral, Patologia Oral Y Cirugia Bucal, 2020
- [The efficacy of glycolic acid, salicylic acid, gluconolactone, and licochalcone A combined with 0.1% adapalene vs adapalene monotherapy in mild-to-moderate acne vulgaris: a double-blinded within-person comparative study](https://pubmed.ncbi.nlm.nih.gov/30858720/) Glycolic acid · Clinical, Cosmetic and Investigational Dermatology, 2019
- [Systematic Study of Paeonol/Madecassoside Co-Delivery Nanoemulsion Transdermal Delivery System for Enhancing Barrier Repair and Anti-Inflammatory Efficacy](https://pubmed.ncbi.nlm.nih.gov/37446936/) Centella asiatica extract · Molecules, 2023
- [The pivotal role of Bifida Ferment Lysate on reinforcing the skin barrier function and maintaining homeostasis of skin defenses in vitro](https://pubmed.ncbi.nlm.nih.gov/37218728/) Bifida ferment filtrate, Bifida lysate ferment · Journal of Cosmetic Dermatology, 2023
- [Efficacy of a multitargeted, salicylic acid-based dermocosmetic cream compared to benzoyl peroxide 5% in Acne vulgaris: Results from a randomized study](https://pubmed.ncbi.nlm.nih.gov/37941097/) Salicylic acid · Journal of Cosmetic Dermatology, 2024
- [Rosmarinic Acid, as an NHE1 Activator, Decreases Skin Surface pH and Improves the Skin Barrier Function](https://pubmed.ncbi.nlm.nih.gov/35409270/) Rosamarinus officinalis leaf extract rosemary leaf extract · International Journal of Molecular Sciences, 2022
- [A Lipid Mixture Enriched by Ceramide NP with Fatty Acids of Diverse Chain Lengths Contributes to Restore the Skin Barrier Function Impaired by Topical Corticosteroid](https://pubmed.ncbi.nlm.nih.gov/34348350/) Ceramide np · Skin Pharmacology and Physiology, 2022
- [Evaluation of dermal extracellular matrix and epidermal-dermal junction modifications using matrix-assisted laser desorption/ionization mass spectrometric imaging, in vivo reflectance confocal microscopy, echography, and histology: effect of age and peptide applications](https://pubmed.ncbi.nlm.nih.gov/25817264/) Palmitoyl tetrapeptide-7 · Journal of Cosmetic Dermatology, 2015
- [A Salicylic Acid-Based Dermocosmetic is Effective as an Adjunct to Benzoyl Peroxide for Mild to Moderate Acne and as Monotherapy in Maintenance Post Benzoyl Peroxide](https://pubmed.ncbi.nlm.nih.gov/38051857/) Salicylic acid · Journal of Drugs in Dermatology, 2023
- [Efficacy and Tolerability of Topical Nicotinamide Plus Antibacterial Adhesive Agents and Zinc-Pyrrolidone Carboxylic Acid Versus Placebo as an Adjuvant Treatment for Moderate Acne Vulgaris in Indonesia: A Multicenter, Double-blind, Randomized, Controlled Trial](https://pubmed.ncbi.nlm.nih.gov/32983333/) Zinc pca · The Journal of Clinical and Aesthetic Dermatology, 2020
- [In vivo and in vitro evaluation of octyl methoxycinnamate liposomes](https://pubmed.ncbi.nlm.nih.gov/24376350/) Ethylhexyl methoxycinnamate · International Journal of Nanomedicine, 2013
- [Lactobionic acid in a natural alkylpolyglucoside-based vehicle: assessing safety and efficacy aspects in comparison to glycolic acid](https://pubmed.ncbi.nlm.nih.gov/20367666/) Lactobionic acid · Journal of Cosmetic Dermatology, 2010
- [Evaluation of the Efficacy and Safety of a Panthenol-Enriched Mask for Skin Barrier Recovery After Facial Laser Treatment: Results of a Double-Blind Randomized Controlled Study](https://pubmed.ncbi.nlm.nih.gov/40613435/) Panthenol · Journal of Cosmetic Dermatology, 2025
- [A 10% Lactobionic acid-containing moisturizer reduces skin surface pH without irritation-An in vivo/in vitro study](https://pubmed.ncbi.nlm.nih.gov/30859734/) Lactobionic acid · Journal of Cosmetic Dermatology, 2019
- [Formulation and evaluation of exotic fat based cosmeceuticals for skin repair](https://pubmed.ncbi.nlm.nih.gov/20046792/) Mangifera indica seed butter · Indian Journal of Pharmaceutical Sciences, 2008
- [Effect of an Emollient Emulsion Containing 15.0% of Caprylic/Capric Triglyceride on the Urocanic Acid of the Stratum Corneum](https://pubmed.ncbi.nlm.nih.gov/37109405/) Caprylic capric triglyceride · Life, 2023
- [Facial disbiosis and UV filters](https://pubmed.ncbi.nlm.nih.gov/39499337/) Ethylhexyl methoxycinnamate · Archives of Dermatological Research, 2024
- [Efficacy of a Topical Formulation on Skin Hydration and Barrier Function in Individuals With Xerosis: A 28-Day Randomized, Split-Leg, Untreated-Controlled Trial](https://pubmed.ncbi.nlm.nih.gov/42108609/) Dipotassium glycyrrhizate · Journal of Cosmetic Dermatology, 2026
- [Low-temperature extracted Portulaca oleracea L. as a functional ingredient in facial masks for photorejuvenation of sensitive skin](https://pubmed.ncbi.nlm.nih.gov/41182319/) Portulaca oleracea extract · Cutaneous and Ocular Toxicology, 2025
- [Retrospective Review of Dermal Safety Studies of Organic Sunscreens](https://pubmed.ncbi.nlm.nih.gov/40911743/) Homosalate · Journal of Drugs in Dermatology, 2025
- [Efficacy and safety of combination cream of stimu-tex AS™ (spent grain wax, Argania Spinosa Kernel oil, Butyrospermum Parkii (shea butter) extract), and saccharide isomerate after fractional CO2 laser procedure: split-face, double blinded, randomized controlled trial](https://pubmed.ncbi.nlm.nih.gov/41134387/) Butyrospermum parkii butter shea butter · Lasers in Medical Science, 2025
- [Targeting Circadian Rhythm for the Regulation of Skin Collagen Metabolism](https://pubmed.ncbi.nlm.nih.gov/41527525/) Palmitoyl tripeptide-1 · Journal of Cosmetic Dermatology, 2026

## The brands

- Skincare: [Skintific](https://lovi.care/skincare/sg/brands/skintific)
- Spanish skincare: [Natura Bissé](https://lovi.care/skincare/sg/brands/natura-bisse)

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## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this comparison: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/compare/skintific-vs-natura-bisse
- United Kingdom: https://lovi.care/skincare/uk/compare/skintific-vs-natura-bisse
- Ireland: https://lovi.care/skincare/ie/compare/skintific-vs-natura-bisse
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- Italy: https://lovi.care/skincare/it/compare/skintific-vs-natura-bisse
- Netherlands: https://lovi.care/skincare/nl/compare/skintific-vs-natura-bisse
- Spain: https://lovi.care/skincare/es/compare/skintific-vs-natura-bisse
- Canada: https://lovi.care/skincare/ca/compare/skintific-vs-natura-bisse
- Australia: https://lovi.care/skincare/au/compare/skintific-vs-natura-bisse
- Singapore: https://lovi.care/skincare/sg/compare/skintific-vs-natura-bisse (this page)
- Saudi Arabia: https://lovi.care/skincare/sa/compare/skintific-vs-natura-bisse
- United Arab Emirates: https://lovi.care/skincare/ae/compare/skintific-vs-natura-bisse