# SkinCeuticals vs Medik8

Page: https://lovi.care/skincare/sg/compare/skinceuticals-vs-medik8

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Singapore.

SkinCeuticals and Medik8 are skincare brands with dedicated followings, featuring American and British roots, respectively. SkinCeuticals offers [serums](https://lovi.care/skincare/sg/ingredients/serum), moisturizers, cleansers, and eye products with [glycerin](https://lovi.care/skincare/sg/ingredients/glycerin), [hyaluronic acid](https://lovi.care/skincare/sg/ingredients/hyaluronic-acid), and [dimethicone](https://lovi.care/skincare/sg/ingredients/dimethicone), which suit oily acne-prone skin best. Medik8 provides serums, moisturizers, eye products, and toners built around hyaluronic acid. While both brands share a focus on hydrating ingredients, they differ in their specific product ranges and regional heritage.

SkinCeuticals is an American skincare brand founded in 1994 and owned by L'Oréal since 2005.

[loreal.com](https://www.loreal.com/-/media/project/loreal/brand-sites/corp/master/lcorp/press-releases/group/historical-press-releases/loreal-to-acquire-skinceuticals/tt3ntc1214pz-1-702.pdf?rev=d0f68bc6ec2b43c7a701cf396299d650) [skinceuticals-za.com](https://www.skinceuticals-za.com/SkinCeuticals/about-us/t774.aspx) [pitchbook.com](https://pitchbook.com/profiles/company/95212-18)

Medik8 is a British skincare brand founded in 2009 and owned by L'Oréal Groupe since 2025.

[loreal.com](https://www.loreal.com/en/press-release/group/l-oreal-groupe-to-acquire-a-majority-stake-in-medik8/) [medik8.com](https://www.medik8.com/pages/founders-story) [tracxn.com](https://tracxn.com/d/companies/medik8/__vqs3N9eL3EfvIq0IoeUPADts7CrlGbzm7kjy9M9QY8o)

This page compares some of the most popular SkinCeuticals and Medik8 products; for every product of both brands, with a fit score for your own skin, [use the Lovi app](https://app.pora.ai/vqqJ/j1xj2b6o?af_sub2=compare&af_sub3=selection_note&af_sub4=pg8fa3a562d2).

### Popular SkinCeuticals vs Medik8 products

#### Medik8

- [Liquid Peptides](https://lovi.care/skincare/sg/p/medik8/liquid-peptides/for/oily-acne-prone-skin) — Average fit
- [CRYSTAL RETINAL 3](https://lovi.care/skincare/sg/p/medik8/crystal-retinal-3/for/mature-skin) — High fit
- [C-Tetra Serum](https://lovi.care/skincare/sg/p/medik8/c-tetra-serum/for/dry-sensitive-skin) — Average fit
- [Bakuchiol Peptides](https://lovi.care/skincare/sg/p/medik8/bakuchiol-peptides/for/dry-skin) — Superior fit
- [Crystal Retinal Ceramide Eye 3](https://lovi.care/skincare/sg/p/medik8/crystal-retinal-ceramide-eye-3/for/mature-skin) — High fit
- [Oxy-R Peptides](https://lovi.care/skincare/sg/p/medik8/oxy-r-peptides/for/mature-skin) — Superior fit
- [Total Moisture Daily Facial Cream](https://lovi.care/skincare/sg/p/medik8/total-moisture-daily-facial-cream/for/mature-skin) — High fit
- [Hydr8 B5 Intense](https://lovi.care/skincare/sg/p/medik8/hydr8-b5-intense/for/dry-skin) — Superior fit

#### SkinCeuticals

- [P-Tiox](https://lovi.care/skincare/sg/p/skinceuticals/p-tiox/for/dry-skin) — Average fit
- [P-TOX](https://lovi.care/skincare/sg/p/skinceuticals/p-tox/for/mature-skin) — High fit
- [Triple Lipid Restore 2:4:2](https://lovi.care/skincare/sg/p/skinceuticals/triple-lipid-restore-2-4-2/for/dry-skin) — Superior fit
- [A.G.E. Advanced Eye](https://lovi.care/skincare/sg/p/skinceuticals/a-g-e-advanced-eye/for/mature-skin) — Superior fit
- [H.A. Intensifier](https://lovi.care/skincare/sg/p/skinceuticals/h-a-intensifier/for/sensitive-skin) — Average fit
- [Hydrating B5 Gel](https://lovi.care/skincare/sg/p/skinceuticals/hydrating-b5-gel/for/dry-skin) — High fit
- [Phyto Corrective Gel](https://lovi.care/skincare/sg/p/skinceuticals/phyto-corrective-gel/for/dry-sensitive-skin) — High fit
- [Phloretin CF](https://lovi.care/skincare/sg/p/skinceuticals/phloretin-cf/for/combination-skin) — High fit

## People Say

SkinCeuticals

Medik8

- Skin smoothing and texture improvement Mostly Mentioned Often Mentioned “definitely gave me a glass skin texture — SkinCeuticals P-TOX” “pores appeared less noticeable — SkinCeuticals P-Tiox” “smoother skin — Medik8 Surface Radiance Cleanse” “My skin was smoother, my skin texture felt more resurfaced. — Medik8 Sleep Glycolic”
- Hydration and moisture Often Mentioned Often Mentioned “Hydrated my skin beautifully. — SkinCeuticals Triple Lipid Restore 2:4:2” “Pure hydration in a bottle — SkinCeuticals Hydrating B5 Gel” “Restores moisture — Medik8 Liquid Peptides” “Instantly quenched the skin — Medik8 Hydr8 B5 Intense”
- Gentle formulation for sensitive skin Sometimes Noted Mostly Mentioned “zero irritation or peeling — Medik8 CRYSTAL RETINAL 3” “only Vitamin C my sensitive skin can tolerate — Medik8 C-Tetra Serum” “Best retinol replacement — Medik8 Bakuchiol Peptides” “Perfect starting strength — SkinCeuticals Retinol 0.3”
- Radiance and brightening Often Mentioned Often Mentioned “I wake up glowing. It adds back that youthful bloom that I've lost. — Medik8 Sleep Glycolic” “unlocked a serious glow — Medik8 C-Tetra Serum” “pigmentation lightened slightly — Medik8 Oxy-R Peptides” “I really love this product, as my skin is brighter. — SkinCeuticals Phloretin CF”
- Lightweight and fast-absorbing texture Often Mentioned Often Mentioned “absorbs quickly — SkinCeuticals Discoloration Defense Serum” “absorbs very quickly — SkinCeuticals P-Tiox” “absorbed effortlessly — Medik8 Total Moisture Daily Facial Cream” “Absorbs instantly — Medik8 Hydr8 B5 Intense”
- Anti-aging and line reduction Often Mentioned Sometimes Noted “reduction in some of the finer lines — SkinCeuticals P-TOX” “softens crow's feet — SkinCeuticals A.G.E. Advanced Eye” “cheeks look fuller — SkinCeuticals H.A. Intensifier” “softened crow's feet — Medik8 Crystal Retinal Ceramide Eye 3”
- High price point Mostly Mentioned Often Mentioned “Expensive per bottle — Medik8 Liquid Peptides” “very expensive for amount — Medik8 CRYSTAL RETINAL 3” “hefty price tag — Medik8 C-Tetra Serum” “Too pricey for the hype — SkinCeuticals P-TOX”
- Lack of results or effectiveness Sometimes Noted Sometimes Noted “haven't noticed much change on the deeper lines — SkinCeuticals P-TOX” “did nothing — SkinCeuticals P-Tiox” “Not as effective as retinol — Medik8 Bakuchiol Peptides” “no difference — Medik8 Oxy-R Peptides”
- Skin irritation and breakouts Sometimes Noted Sometimes Noted “skin feeling parched — SkinCeuticals Blemish + Age Defense” “skin went through a slight purge — SkinCeuticals P-TOX” “stinging sensation — Medik8 Super C Ferulic” “made me break out constantly — Medik8 C-Tetra Serum”

### SkinCeuticals vs Medik8 [serums](https://lovi.care/skincare/sg/ingredients/serum) and treatments

#### Medik8

- [Liquid Peptides](https://lovi.care/skincare/sg/p/medik8/liquid-peptides/for/oily-acne-prone-skin) — Average fit
- [CRYSTAL RETINAL 3](https://lovi.care/skincare/sg/p/medik8/crystal-retinal-3/for/mature-skin) — High fit
- [C-Tetra Serum](https://lovi.care/skincare/sg/p/medik8/c-tetra-serum/for/dry-sensitive-skin) — Average fit
- [Bakuchiol Peptides](https://lovi.care/skincare/sg/p/medik8/bakuchiol-peptides/for/dry-skin) — Superior fit
- [Oxy-R Peptides](https://lovi.care/skincare/sg/p/medik8/oxy-r-peptides/for/mature-skin) — Superior fit
- [Super C Ferulic](https://lovi.care/skincare/sg/p/medik8/super-c-ferulic/for/acne-prone-skin) — High fit
- [Sleep Glycolic](https://lovi.care/skincare/sg/p/medik8/sleep-glycolic/for/oily-acne-prone-skin) — Average fit

#### SkinCeuticals

- [P-TOX](https://lovi.care/skincare/sg/p/skinceuticals/p-tox/for/mature-skin) — High fit
- [Phyto Corrective Gel](https://lovi.care/skincare/sg/p/skinceuticals/phyto-corrective-gel/for/dry-sensitive-skin) — High fit
- [Phloretin CF](https://lovi.care/skincare/sg/p/skinceuticals/phloretin-cf/for/combination-skin) — High fit
- [Discoloration Defense Serum](https://lovi.care/skincare/sg/p/skinceuticals/discoloration-defense-serum/for/dark-spots) — Superior fit
- [Retinol 0.3](https://lovi.care/skincare/sg/p/skinceuticals/retinol-0-3/for/acne-prone-skin) — High fit — [S$146.30 at Amazon](https://www.amazon.sg/dp/B07MKXJPXW?tag=lovi-care-web-product0e-22&linkCode=osi&th=1&psc=1)
- [Blemish + Age Defense](https://lovi.care/skincare/sg/p/skinceuticals/blemish-age-defense/for/oily-skin) — Superior fit
- [A.G.E. Interrupter](https://lovi.care/skincare/sg/p/skinceuticals/a-g-e-interrupter/for/dry-skin) — Warning fit
- [Silymarin CF](https://lovi.care/skincare/sg/p/skinceuticals/silymarin-cf/for/oily-skin) — Superior fit
- [Glycolic 10 Renew Overnight](https://lovi.care/skincare/sg/p/skinceuticals/glycolic-10-renew-overnight/for/oily-acne-prone-skin) — High fit
- [Redness Neutralizer](https://lovi.care/skincare/sg/p/skinceuticals/redness-neutralizer/for/sensitive-skin) — High fit
- [Retexturing Activator](https://lovi.care/skincare/sg/p/skinceuticals/retexturing-activator/for/dry-skin) — Superior fit
- [Serum 10](https://lovi.care/skincare/sg/p/skinceuticals/serum-10/for/dry-skin) — High fit
- [Cell Cycle Catalyst](https://lovi.care/skincare/sg/p/skinceuticals/cell-cycle-catalyst/for/oily-acne-prone-skin) — Average fit
- [Retinol 1.0 Maximum Strength Refining Night Cream](https://lovi.care/skincare/sg/p/skinceuticals/retinol-1-0-maximum-strength-refining-night-cream/for/oily-acne-prone-skin) — Average fit
- [C E Ferulic](https://lovi.care/skincare/sg/p/skinceuticals/c-e-ferulic/for/dry-sensitive-skin) — Superior fit

## Questions and answers

### SkinCeuticals or Medik8: which is better?

Medik8 is better for gentle formulations on sensitive skin and brightening, while SkinCeuticals is better for anti-aging and line reduction, according to the products on this page. Both brands deliver equal skin smoothing, texture improvement, and hydration.

### What is the difference between SkinCeuticals and Medik8?

SkinCeuticals excels in anti-aging and line reduction, while Medik8 does better in gentle formulation for sensitive skin and radiance brightening.

### SkinCeuticals or Medik8: which cleanser is better?

SkinCeuticals offers a wider range of cleansers on this page with high fit levels for oily and acne-prone skin, such as Simply Clean Gel, whereas Medik8 features Surface Radiance Cleanse as a top-performing cleanser for those concerns.

### Which is more affordable, SkinCeuticals or Medik8?

Reviewers on this page indicate that both SkinCeuticals and Medik8 have a high price point.

### Which causes fewer breakouts, SkinCeuticals or Medik8?

SkinCeuticals and Medik8 are equal when it comes to skin irritation and breakouts.

### Between SkinCeuticals and Medik8, which brand is better suited for sensitive skin?

Medik8 is better suited for sensitive skin, as its formulations are noted for being gentle and non-irritating.

### How do the founding years and corporate ownership of SkinCeuticals and Medik8 compare?

SkinCeuticals was founded in the United States in 1994 and has been owned by L'Oréal since 2005, whereas Medik8 was founded in the United Kingdom in 2009 and is owned by L'Oréal Groupe as of 2025.

### Which brand has a wider variety of fragrance-free products, SkinCeuticals or Medik8?

SkinCeuticals has a wider variety of fragrance-free products on this page, featuring 34 out of 37 fragrance-free options compared to Medik8's 11 out of 12.

### SkinCeuticals or Medik8: which moisturizer is better?

SkinCeuticals Triple Lipid Restore 2:4:2 helps dry skin with a Superior fit, while Medik8 Total Moisture Daily Facial Cream provides a High fit for mature, dry, and sensitive skin. Both ranges rely on key hydrators like [hyaluronic acid](https://lovi.care/skincare/sg/ingredients/hyaluronic-acid) to support skin quality and moisture.

[Dermatologic Therapy, 2022](https://pubmed.ncbi.nlm.nih.gov/36200921/)

## Research behind their key ingredients

- [Vitamin A antagonizes decreased cell growth and elevated collagen-degrading matrix metalloproteinases and stimulates collagen accumulation in naturally aged human skin](https://pubmed.ncbi.nlm.nih.gov/10692106/) Retinol · The Journal of Investigative Dermatology, 2000
- [Hyaluronic acid and wound healing](https://pubmed.ncbi.nlm.nih.gov/25877441/) Sodium hyaluronate · Journal of Pharmacy & Pharmaceutical Sciences, 2015
- [The effect of niacinamide on reducing cutaneous pigmentation and suppression of melanosome transfer](https://pubmed.ncbi.nlm.nih.gov/12100180/) Niacinamide · The British Journal of Dermatology, 2002
- [Skin delivery of epigallocatechin-3-gallate (EGCG) and hyaluronic acid loaded nano-transfersomes for antioxidant and anti-aging effects in UV radiation induced skin damage](https://pubmed.ncbi.nlm.nih.gov/28155509/) Hyaluronic acid · Drug Delivery, 2017
- [Mechanistic Basis and Clinical Evidence for the Applications of Nicotinamide (Niacinamide) to Control Skin Aging and Pigmentation](https://pubmed.ncbi.nlm.nih.gov/34439563/) Niacinamide · Antioxidants, 2021
- [Benefits of topical hyaluronic acid for skin quality and signs of skin aging: From literature review to clinical evidence](https://pubmed.ncbi.nlm.nih.gov/36200921/) Hyaluronic acid, Sodium hyaluronate · Dermatologic Therapy, 2022
- [Topical use of dexpanthenol in skin disorders](https://pubmed.ncbi.nlm.nih.gov/12113650/) Panthenol · American Journal of Clinical Dermatology, 2002
- [The Effect of Aloe Vera Clinical Trials on Prevention and Healing of Skin Wound: A Systematic Review](https://pubmed.ncbi.nlm.nih.gov/30666070/) Aloe barbadensis leaf juice powder, Aloe barbadensis · Iranian Journal of Medical Sciences, 2019
- [Caffeine's mechanisms of action and its cosmetic use](https://pubmed.ncbi.nlm.nih.gov/23075568/) Caffeine · Skin Pharmacology and Physiology, 2013
- [Improvement of naturally aged skin with vitamin A (retinol)](https://pubmed.ncbi.nlm.nih.gov/17515510/) Retinol · Archives of Dermatology, 2007
- [A topical antioxidant solution containing vitamins C and E stabilized by ferulic acid provides protection for human skin against damage caused by ultraviolet irradiation](https://pubmed.ncbi.nlm.nih.gov/18603326/) Ferulic acid · Journal of the American Academy of Dermatology, 2008
- [Anti-aging and brightening effects of a topical treatment containing vitamin C, vitamin E, and raspberry leaf cell culture extract: A split-face, randomized controlled trial](https://pubmed.ncbi.nlm.nih.gov/31975502/) Tocopherol vitamin e, Tocopherol, Ascorbic acid · Journal of Cosmetic Dermatology, 2020
- [Protective effects of a topical antioxidant mixture containing vitamin C, ferulic acid, and phloretin against ultraviolet-induced photodamage in human skin](https://pubmed.ncbi.nlm.nih.gov/19146606/) Ferulic acid · Journal of Cosmetic Dermatology, 2008
- [Molecular basis of retinol anti-ageing properties in naturally aged human skin in vivo](https://pubmed.ncbi.nlm.nih.gov/27261203/) Retinol · International Journal of Cosmetic Science, 2017
- [Effects of menthol and cold on histamine-induced itch and skin reactions in man](https://pubmed.ncbi.nlm.nih.gov/7624016/) Menthol · Neuroscience Letters, 1995
- [Production and characterization of cosmetic nanoemulsions containing Opuntia ficus-indica (L.) mill extract as moisturizing agent](https://pubmed.ncbi.nlm.nih.gov/25648593/) Hydrolyzed opuntia ficus-indica flower extract · Molecules, 2015
- [Topical anti-inflammatory effects of isorhamnetin glycosides isolated from Opuntia ficus-indica](https://pubmed.ncbi.nlm.nih.gov/25821823/) Hydrolyzed opuntia ficus-indica flower extract · BioMed Research International, 2015
- [Anti-Wrinkle Benefits of Peptides Complex Stimulating Skin Basement Membrane Proteins Expression](https://pubmed.ncbi.nlm.nih.gov/31861912/) Advanced peptide complex · International Journal of Molecular Sciences, 2019
- [Prospective, randomized, double-blind assessment of topical bakuchiol and retinol for facial photoageing](https://pubmed.ncbi.nlm.nih.gov/29947134/) Bakuchiol · The British Journal of Dermatology, 2019
- [Apigenin inhibits UVA-induced cytotoxicity in vitro and prevents signs of skin aging in vivo](https://pubmed.ncbi.nlm.nih.gov/27279007/) Chamomilla recutita flower extract, Chamomilla recutita extract · International Journal of Molecular Medicine, 2016
- [Topical delivery of tetrahydrocurcumin lipid nanoparticles effectively inhibits skin inflammation: in vitro and in vivo study](https://pubmed.ncbi.nlm.nih.gov/29938544/) Tetrahydrodiferuloylmethane · Drug Development and Industrial Pharmacy, 2018
- [Effect of fermentation time on the content of bioactive compounds with cosmetic and dermatological properties in Kombucha Yerba Mate extracts](https://pubmed.ncbi.nlm.nih.gov/34552134/) Saccharomyces xylinum black tea ferment · Scientific Reports, 2021
- [Vitamin C-squalene bioconjugate promotes epidermal thickening and collagen production in human skin](https://pubmed.ncbi.nlm.nih.gov/33037252/) Squalane · Scientific Reports, 2020
- [Treatment of acne with a combination of propolis, tea tree oil, and Aloe vera compared to erythromycin cream: two double-blind investigations](https://pubmed.ncbi.nlm.nih.gov/30588129/) Aloe barbadensis leaf juice · Clinical Pharmacology, 2018
- [Urea: a comprehensive review of the clinical literature](https://pubmed.ncbi.nlm.nih.gov/24314769/) Urea · Dermatology Online Journal, 2013
- [Alteration of barrier properties, stratum corneum ceramides and microbiome composition in response to lotion application on cosmetic dry skin](https://pubmed.ncbi.nlm.nih.gov/35340018/) Ceramides · Scientific Reports, 2022
- [Effects of glyceryl glucoside on AQP3 expression, barrier function and hydration of human skin](https://pubmed.ncbi.nlm.nih.gov/22584263/) Glyceryl glucoside · Skin Pharmacology and Physiology, 2012
- [Antioxidant Opuntia ficus-indica Extract Activates AHR-NRF2 Signaling and Upregulates Filaggrin and Loricrin Expression in Human Keratinocytes](https://pubmed.ncbi.nlm.nih.gov/26061570/) Hydrolyzed opuntia ficus-indica flower extract · Journal of Medicinal Food, 2015
- [Ceramide 1 and ceramide 3 act synergistically on skin hydration and the transepidermal water loss of sodium lauryl sulfate-irritated skin](https://pubmed.ncbi.nlm.nih.gov/18717861/) Ceramide eop, Ceramide np · International Journal of Dermatology, 2008
- [Effect of a topical antioxidant serum containing vitamin C, vitamin E, and ferulic acid after Q-switched 1064-nm Nd:YAG laser for treatment of environment-induced skin pigmentation](https://pubmed.ncbi.nlm.nih.gov/32052907/) Tocopherol vitamin e, Ferulic acid · Journal of Cosmetic Dermatology, 2020
- [Licochalcone A activates Nrf2 in vitro and contributes to licorice extract-induced lowered cutaneous oxidative stress in vivo](https://pubmed.ncbi.nlm.nih.gov/25381913/) Glycyrrhiza glabra extract · Experimental Dermatology, 2015
- [Tailoring of Retinyl Palmitate-Based Ethosomal Hydrogel as a Novel Nanoplatform for Acne Vulgaris Management: Fabrication, Optimization, and Clinical Evaluation Employing a Split-Face Comparative Study](https://pubmed.ncbi.nlm.nih.gov/34211271/) Retinyl palmitate · International Journal of Nanomedicine, 2021
- [Inhibitory effect of mulberroside A and its derivatives on melanogenesis induced by ultraviolet B irradiation](https://pubmed.ncbi.nlm.nih.gov/21946069/) Hydroxyresveratrol · Food and Chemical Toxicology, 2011
- [Clinical, biometric and structural evaluation of the long-term effects of a topical treatment with ascorbic acid and madecassoside in photoaged human skin](https://pubmed.ncbi.nlm.nih.gov/18503551/) Centella asiatica leaf extract · Experimental Dermatology, 2008
- [The 24-hour skin hydration and barrier function effects of a hyaluronic 1%, glycerin 5%, and Centella asiatica stem cells extract moisturizing fluid: an intra-subject, randomized, assessor-blinded study](https://pubmed.ncbi.nlm.nih.gov/28860834/) Glycerin · Clinical, Cosmetic and Investigational Dermatology, 2017
- [Randomized controlled study for the anti-aging effect of human adipocyte-derived mesenchymal stem cell media combined with niacinamide after laser therapy](https://pubmed.ncbi.nlm.nih.gov/33103316/) Niacinamide · Journal of Cosmetic Dermatology, 2021
- [Protective effects of a new phloretin derivative against UVB-induced damage in skin cell model and human volunteers](https://pubmed.ncbi.nlm.nih.gov/25334063/) Phloretin · International Journal of Molecular Sciences, 2014
- [Topical taurine bromamine, a new candidate in the treatment of moderate inflammatory acne vulgaris: a pilot study](https://pubmed.ncbi.nlm.nih.gov/18573718/) Taurine · European Journal of Dermatology, 2008
- [The anti-wrinkle efficacy of argireline, a synthetic hexapeptide, in Chinese subjects: a randomized, placebo-controlled study](https://pubmed.ncbi.nlm.nih.gov/23417317/) Acetyl hexapeptide-8 · American Journal of Clinical Dermatology, 2013
- [Evaluation of Cosmetic and Dermatological Properties of Kombucha-Fermented Berry Leaf Extracts Considered to Be By-Products](https://pubmed.ncbi.nlm.nih.gov/35408743/) Saccharomyces xylinum black tea ferment · Molecules, 2022
- [Treatment of human skin with an extract of Fucus vesiculosus changes its thickness and mechanical properties](https://pubmed.ncbi.nlm.nih.gov/11917251/) Algae extract · Journal of Cosmetic Science, 2002
- [Senomorphic activity of a combination of niacinamide and hyaluronic acid: correlation with clinical improvement of skin aging](https://pubmed.ncbi.nlm.nih.gov/39009698/) Niacinamide · Scientific Reports, 2024
- [A new topical panthenol-containing emollient: Results from two randomized controlled studies assessing its skin moisturization and barrier restoration potential, and the effect on skin microflora](https://pubmed.ncbi.nlm.nih.gov/27425824/) Panthenol · The Journal of Dermatological Treatment, 2017
- [Safety and Toxicological Evaluation of a Novel, Standardized 3-O-Acetyl-11-keto-beta-Boswellic Acid (AKBA)-Enriched Boswellia serrata Extract (5-Loxin(R))](https://pubmed.ncbi.nlm.nih.gov/20021046/) Boswellia serrata extract, Boswellia serrata gum · Toxicology Mechanisms and Methods, 2006
- [A Double-Blinded, Randomized, Vehicle-Controlled Study of the Efficacy of Moisturizer Containing Licochalcone A, Decanediol, L-Carnitine, and Salicylic Acid for Prevention of Acne Relapse in Asian Population](https://pubmed.ncbi.nlm.nih.gov/33150170/) Salicylic acid · BioMed Research International, 2020
- [Stable Ozonides with Vitamin E Acetate versus Corticosteroid in the Treatment of Lichen Sclerosus in Foreskin: Evaluation of Effects on Inflammation](https://pubmed.ncbi.nlm.nih.gov/30991399/) Tocopheryl acetate · Urologia Internationalis, 2019
- [Microneedling by dermapen and glycolic acid peel for the treatment of acne scars: Comparative study](https://pubmed.ncbi.nlm.nih.gov/30548170/) Glycolic acid · Journal of Cosmetic Dermatology, 2019
- [Formulation and evaluation on human skin of a water-in-oil emulsion containing Muscat hamburg black grape seed extract](https://pubmed.ncbi.nlm.nih.gov/25402429/) Grape seed oil · International Journal of Cosmetic Science, 2015
- [A randomized, single-blinded trial of a tripeptide/hexapeptide healing regimen following laser resurfacing of the face](https://pubmed.ncbi.nlm.nih.gov/28371204/) Hexapeptide · Journal of Cosmetic Dermatology, 2017
- [Effects of lecithin-based nanoemulsions on skin: Short-time cytotoxicity MTT and BrdU studies, skin penetration of surfactants and additives and the delivery of curcumin](https://pubmed.ncbi.nlm.nih.gov/32165223/) Hydrogenated lecithin · International Journal of Pharmaceutics, 2020
- [Treatment of xerosis with a topical formulation containing glyceryl glucoside, natural moisturizing factors, and ceramide](https://pubmed.ncbi.nlm.nih.gov/22916312/) Moisturizing factors nmf, Glyceryl glucoside · The Journal of Clinical and Aesthetic Dermatology, 2012
- [Comparative study of efficacy and safety of 45% mandelic acid versus 30% salicylic acid peels in mild-to-moderate acne vulgaris](https://pubmed.ncbi.nlm.nih.gov/31553119/) Mandelic acid · Journal of Cosmetic Dermatology, 2020
- [Evaluation of anti-acne properties of phloretin in vitro and in vivo](https://pubmed.ncbi.nlm.nih.gov/26212527/) Phloretin · International Journal of Cosmetic Science, 2016
- [The efficacy of glycolic acid, salicylic acid, gluconolactone, and licochalcone A combined with 0.1% adapalene vs adapalene monotherapy in mild-to-moderate acne vulgaris: a double-blinded within-person comparative study](https://pubmed.ncbi.nlm.nih.gov/30858720/) Gluconolactone, Glycolic acid · Clinical, Cosmetic and Investigational Dermatology, 2019
- [High molecular compounds (polysaccharides and proanthocyanidins) from Hamamelis virginiana bark: influence on human skin keratinocyte proliferation and differentiation and influence on irritated skin](https://pubmed.ncbi.nlm.nih.gov/11684194/) Witch hazel · Phytochemistry, 2001
- [Efficacy of a topical gel containing chitosan, chlorhexidine, allantoin and dexpanthenol for pain and inflammation control after third molar surgery: A randomized and placebo-controlled clinical trial](https://pubmed.ncbi.nlm.nih.gov/32683390/) Allantoin, Panthenol · Medicina Oral, Patologia Oral Y Cirugia Bucal, 2020
- [Sunscreens and Cosmetic Formulations Containing Ascorbyl Tetraisopalmitate and Rice Peptides for the Improvement of Skin Photoaging: A Double-blind, Randomized Placebo-controlled Clinical Study](https://pubmed.ncbi.nlm.nih.gov/33529350/) Tetrahexyldecyl ascorbate · Photochemistry and Photobiology, 2021
- [Clinical evidence of the efficacy and safety of a new 3-in-1 anti-aging topical night serum-in-oil containing melatonin, bakuchiol, and ascorbyl tetraisopalmitate: 103 females treated from 28 to 84 days](https://pubmed.ncbi.nlm.nih.gov/30924254/) Tetrahexyldecyl ascorbate · Journal of Cosmetic Dermatology, 2019
- [Anti-Wrinkle Efficacy of Cross-Linked Hyaluronic Acid-Based Microneedle Patch with Acetyl Hexapeptide-8 and Epidermal Growth Factor on Korean Skin](https://pubmed.ncbi.nlm.nih.gov/33911590/) Acetyl hexapeptide-8 · Annals of Dermatology, 2019
- [Efficacy of olive leaf extract-containing cream for facial rejuvenation: A pilot study](https://pubmed.ncbi.nlm.nih.gov/32333467/) Olea europaea leaf extract olive leaf extract · Journal of Cosmetic Dermatology, 2020
- [Taurine bromamine (TauBr)--its role in immunity and new perspectives for clinical use](https://pubmed.ncbi.nlm.nih.gov/20804605/) Taurine · Journal of Biomedical Science, 2010
- [Allergy to oxidized limonene and linalool is frequent in the U.K](https://pubmed.ncbi.nlm.nih.gov/24702129/) Citrus aurantium dulcis peel oil · The British Journal of Dermatology, 2014
- [Systematic Study of Paeonol/Madecassoside Co-Delivery Nanoemulsion Transdermal Delivery System for Enhancing Barrier Repair and Anti-Inflammatory Efficacy](https://pubmed.ncbi.nlm.nih.gov/37446936/) Centella asiatica leaf extract · Molecules, 2023
- [A comparative study of gluconolactone versus benzoyl peroxide in the treatment of acne](https://pubmed.ncbi.nlm.nih.gov/1303072/) Gluconolactone · The Australasian Journal of Dermatology, 1992
- [Efficacy of a multitargeted, salicylic acid-based dermocosmetic cream compared to benzoyl peroxide 5% in Acne vulgaris: Results from a randomized study](https://pubmed.ncbi.nlm.nih.gov/37941097/) Salicylic acid · Journal of Cosmetic Dermatology, 2024
- [Comparative Study of 35% Glycolic Acid, 20% Salicylic-10% Mandelic Acid, and Phytic Acid Combination Peels in the Treatment of Active Acne and Postacne Pigmentation](https://pubmed.ncbi.nlm.nih.gov/31619887/) Phytic acid · Journal of Cutaneous and Aesthetic Surgery, 2019
- [Biomimetic hyaluronic acid-stabilized zinc oxide nanoparticles in acne treatment: A preclinical and clinical approach](https://pubmed.ncbi.nlm.nih.gov/40254135/) Zinc oxide · Journal of Controlled Release, 2025
- [Fatty acids based α-Tocopherol loaded nanostructured lipid carrier gel: In vitro and in vivo evaluation for moisturizing and anti-aging effects](https://pubmed.ncbi.nlm.nih.gov/32129554/) Vitamin e · Journal of Cosmetic Dermatology, 2020
- [A Lipid Mixture Enriched by Ceramide NP with Fatty Acids of Diverse Chain Lengths Contributes to Restore the Skin Barrier Function Impaired by Topical Corticosteroid](https://pubmed.ncbi.nlm.nih.gov/34348350/) Ceramide np · Skin Pharmacology and Physiology, 2022
- [Evaluation of dermal extracellular matrix and epidermal-dermal junction modifications using matrix-assisted laser desorption/ionization mass spectrometric imaging, in vivo reflectance confocal microscopy, echography, and histology: effect of age and peptide applications](https://pubmed.ncbi.nlm.nih.gov/25817264/) Palmitoyl oligopeptide · Journal of Cosmetic Dermatology, 2015
- [Efficacy and safety of moisturizer containing 5% panthenol, madecassoside, and copper-zinc-manganese versus 0.02% triamcinolone acetonide cream in decreasing adverse reaction and downtime after ablative fractional carbon dioxide laser resurfacing: A split-face, double-blinded, randomized, controlled trial](https://pubmed.ncbi.nlm.nih.gov/30945430/) Centella asiatica leaf extract · Journal of Cosmetic Dermatology, 2019
- [A Salicylic Acid-Based Dermocosmetic is Effective as an Adjunct to Benzoyl Peroxide for Mild to Moderate Acne and as Monotherapy in Maintenance Post Benzoyl Peroxide](https://pubmed.ncbi.nlm.nih.gov/38051857/) Salicylic acid · Journal of Drugs in Dermatology, 2023
- [Comparison of skin calming effects of cosmetic products containing 4-t-butylcyclohexanol or acetyl dipeptide-1 cetyl ester on capsaicin-induced facial stinging in volunteers with sensitive skin](https://pubmed.ncbi.nlm.nih.gov/26805418/) Acetyl dipeptide-1 cetyl ester · Journal of the European Academy of Dermatology and Venereology, 2016
- [Oxidized citrus oil (R-limonene): a frequent skin sensitizer in Europe](https://pubmed.ncbi.nlm.nih.gov/12399762/) Citrus aurantium dulcis peel oil · Journal of the American Academy of Dermatology, 2002
- [Efficacy of a topical serum containing L-ascorbic acid, neohesperidin, pycnogenol, tocopherol, and hyaluronic acid in relation to skin aging signs](https://pubmed.ncbi.nlm.nih.gov/35150043/) Vitamin e · Journal of Cosmetic Dermatology, 2022
- [Antioxidant-based topical formulations influence on the inflammatory response of Japanese skin: A clinical study using non-invasive techniques](https://pubmed.ncbi.nlm.nih.gov/28385617/) Tetrahexyldecyl ascorbate · European Journal of Pharmaceutics and Biopharmaceutics, 2017
- [A dermocosmetic containing bakuchiol, Ginkgo biloba extract and mannitol improves the efficacy of adapalene in patients with acne vulgaris: result from a controlled randomized trial](https://pubmed.ncbi.nlm.nih.gov/25914553/) Bakuchiol · Clinical, Cosmetic and Investigational Dermatology, 2015
- [Retaining Skin Barrier Function Properties of the Stratum Corneum with Components of the Natural Moisturizing Factor-A Randomized, Placebo-Controlled Double-Blind In Vivo Study](https://pubmed.ncbi.nlm.nih.gov/33809557/) Moisturizing factors nmf · Molecules, 2021
- [Challenging the safety and efficacy of topically applied chlorogenic acid, apigenin, kaempferol, and naringenin by HET-CAM, HPLC-TBARS-EVSC, and laser Doppler flowmetry](https://pubmed.ncbi.nlm.nih.gov/38831914/) Grapefruit fruit extract · Frontiers in Chemistry, 2024
- [Development of stable tocopherol succinate-loaded ethosomes to enhance transdermal permeation: In vitro and in vivo characterizations](https://pubmed.ncbi.nlm.nih.gov/35274433/) Vitamin e · Journal of Cosmetic Dermatology, 2022
- [Topical application of jojoba (Simmondsia chinensis L.) wax enhances the synthesis of pro-collagen III and hyaluronic acid and reduces inflammation in the ex-vivo human skin organ culture model](https://pubmed.ncbi.nlm.nih.gov/38344180/) Jojoba seed oil · Frontiers in Pharmacology, 2024
- [Clinical evaluation of the efficacy of a facial serum containing dioic acid, glycolic acid, salicylic acid, LHA, citric acid, and HEPES in treating post-inflammatory hyperchromia and controlling oily skin in patients with acne vulgaris](https://pubmed.ncbi.nlm.nih.gov/33617668/) Capryloyl salicylic acid, Hydroxyethylpiperazine ethane sulfonic acid, Citric acid · Journal of Cosmetic Dermatology, 2021
- [Evaluation of moisturizing and irritation potential of sacha inchi oil](https://pubmed.ncbi.nlm.nih.gov/31441999/) Plukenetia volubilis seed oil · Journal of Cosmetic Dermatology, 2020
- [Assessment of Cosmetic and Dermatological Properties and Safety of Use of Model Skin Tonics with Kombucha-Fermented Red Berry Extracts](https://pubmed.ncbi.nlm.nih.gov/36499003/) Saccharomyces xylinum black tea ferment · International Journal of Molecular Sciences, 2022
- [A randomized, double-blind, vehicle-controlled study of a preparation containing undecylenoyl phenylalanine 2% in the treatment of solar lentigines](https://pubmed.ncbi.nlm.nih.gov/19874316/) Undecylenoyl phenylalanine · Clinical and Experimental Dermatology, 2010
- [Fractional microneedle radiofrequency with the application of vitamin C, E, and ferulic acid serum for neck skin rejuvenation: a prospective, double-blinded, split-neck, placebo-controlled trial](https://pubmed.ncbi.nlm.nih.gov/40464749/) Ferulic acid · The Journal of Dermatological Treatment, 2025
- [Antiaging, Brightening, and Antioxidant Efficacy of Fermented Bilberry Extract (Vaccinium myrtillus): A Randomized, Double-Blind, Placebo-Controlled Trial](https://pubmed.ncbi.nlm.nih.gov/39064646/) Vaccinium myrtillus fruit extract · Nutrients, 2024
- [Development of grape seed extract based formulations by using non-invasive biophysical technique and its impact on skin aging](https://pubmed.ncbi.nlm.nih.gov/34799340/) Grape seed oil · Pakistan Journal of Pharmaceutical Sciences, 2021
- [Effect of seasonal and geographical differences on skin and effect of treatment with an osmoprotectant: Sorbitol](https://pubmed.ncbi.nlm.nih.gov/23752031/) Sorbitol · Journal of Cosmetic Science, 2013
- [Efficacy of octenidine dihydrochloride and 2-phenoxyethanol in the topical treatment of inflammatory acne](https://pubmed.ncbi.nlm.nih.gov/18853079/) Phenoxyethanol · Acta Dermatovenerologica Alpina, Pannonica, Et Adriatica, 2008
- [Development of solid lipid microparticles (SLMs) containing asiatic acid for topical treatment of acne: Characterization, stability, in vitro and in vivo anti-acne assessment](https://pubmed.ncbi.nlm.nih.gov/38460769/) Centella asiatica leaf extract · International Journal of Pharmaceutics, 2024
- [Synergetic Effects of Aloe Vera Extract with Trimethylglycine for Targeted Aquaporin 3 Regulation and Long-Term Skin Hydration](https://pubmed.ncbi.nlm.nih.gov/38611819/) Aloe barbadensis flower extract · Molecules, 2024
- [Squalane as a Promising Agent Protecting UV-Induced Inhibition of Collagen Biosynthesis and Wound Healing in Human Dermal Fibroblast](https://pubmed.ncbi.nlm.nih.gov/40363772/) Squalane · Molecules, 2025
- [Clinical Development and Evaluation of a Multi-Component Dissolving Microneedle Patch for Skin Pigmentation Disorders](https://pubmed.ncbi.nlm.nih.gov/37571190/) 3-o-ethyl ascorbic acid · Polymers, 2023
- [Safety assessment of a novel water-soluble extract of Boswellia serrata gum resin: acute toxicity, 90-day sub-chronic toxicity, Ames' bacterial reverse mutation, and in vivo micronucleus assays](https://pubmed.ncbi.nlm.nih.gov/34886755/) Boswellia serrata extract, Boswellia serrata gum · Toxicology Mechanisms and Methods, 2022
- [Depth-dependent hydration dynamics in human skin: Vehicle-controlled efficacy assessment of a functional 10% urea plus NMF moisturizer by near-infrared confocal spectroscopic imaging (KOSIM IR) and capacitance method complemented by volunteer perception](https://pubmed.ncbi.nlm.nih.gov/35034387/) Moisturizing factors nmf · Skin Research and Technology, 2022
- [Effect of hydroxypropyl-β-cyclodextrin in fluid and semi-solid submicron emulsions on physiological skin parameters during regular in vivo application](https://pubmed.ncbi.nlm.nih.gov/33236374/) Cyclodextrin · International Journal of Cosmetic Science, 2021
- [Synergistic action of a triple peptide complex on an essential extra-cellular matrix protein exhibits significant anti-aging benefits](https://pubmed.ncbi.nlm.nih.gov/20618556/) Advanced peptide complex · Journal of Cosmetic Dermatology, 2010
- [Semi-solid functionalized nanostructured lipid carriers loading thymol for skin disorders](https://pubmed.ncbi.nlm.nih.gov/38142012/) Thymus vulgaris extract · International Journal of Pharmaceutics, 2024
- [A controlled, three-part trial to investigate the barrier function and skin hydration properties of six skin protectants](https://pubmed.ncbi.nlm.nih.gov/16439809/) Dimethicone · Ostomy/wound Management, 2005
- [Influence of vitamin E acetate on stratum corneum hydration](https://pubmed.ncbi.nlm.nih.gov/9706379/) Tocopheryl acetate · Arzneimittel-Forschung, 1998
- [A randomized controlled study to evaluate the depigmenting activity of L-ascorbic acid plus phytic acid-serum vs. placebo on solar lentigines](https://pubmed.ncbi.nlm.nih.gov/22151934/) Phytic acid · Journal of Cosmetic Dermatology, 2011
- [Anti-inflammatory and skin-hydrating properties of a dietary supplement and topical formulations containing oligomeric proanthocyanidins](https://pubmed.ncbi.nlm.nih.gov/17035721/) Grape seed oil · Skin Pharmacology and Physiology, 2007
- [Topical Zinc Oxide Nanoparticle Formulations for Acne Vulgaris: A Systematic Review of Pre-Clinical and Early-Phase Clinical Evidence](https://pubmed.ncbi.nlm.nih.gov/41007718/) Zinc oxide · Biomedicines, 2025
- [Emulgels Containing Perilla frutescens Seed Oil, Moringa oleifera Seed Oil, and Mixed Seed Oil: Microemulsion and Safety Assessment](https://pubmed.ncbi.nlm.nih.gov/35745923/) Moringa oleifera seed oil · Polymers, 2022
- [Assessment of the efficacy and safety of a new complex skin cream in Asian women: A controlled clinical trial](https://pubmed.ncbi.nlm.nih.gov/28512843/) Hydroxyresveratrol · Journal of Cosmetic Dermatology, 2017
- [A randomized controlled trial to compare the effectiveness and safety of adsorbent lotion containing tapioca starch, spent grain wax, Butyrospermum parkii extract, argania spinosa kernel oil, aloe barbadensis, rosehip oil, and allantoin with a low-potency topical corticosteroid in the treatment of intertrigo](https://pubmed.ncbi.nlm.nih.gov/33811776/) Shea butter · Journal of Cosmetic Dermatology, 2022
- [Lactobionic acid in a natural alkylpolyglucoside-based vehicle: assessing safety and efficacy aspects in comparison to glycolic acid](https://pubmed.ncbi.nlm.nih.gov/20367666/) Pha polyhydroxy acid · Journal of Cosmetic Dermatology, 2010
- [A Randomized, Investigator-Blinded, Split-Face, Controlled Trial Evaluating the Efficacy and Satisfaction of a Topical Product Containing Blueberry Extract and Pro-Xylane Combined With Micro-Focused Ultrasound for Anti-aging](https://pubmed.ncbi.nlm.nih.gov/40635529/) Blueberry extract, Proxylane · Journal of Cosmetic Dermatology, 2025
- [Evaluation of the Efficacy and Safety of a Panthenol-Enriched Mask for Skin Barrier Recovery After Facial Laser Treatment: Results of a Double-Blind Randomized Controlled Study](https://pubmed.ncbi.nlm.nih.gov/40613435/) Panthenol · Journal of Cosmetic Dermatology, 2025
- [Cucumber (Cucumis sativus L.) with heterologous poly-γ-glutamic acid has skin moisturizing, whitening and anti-wrinkle effects](https://pubmed.ncbi.nlm.nih.gov/38336313/) Cucumis sativus fruit extract · International Journal of Biological Macromolecules, 2024
- [Effects of topical boswellic acid on photo and age-damaged skin: clinical, biophysical, and echographic evaluations in a double-blind, randomized, split-face study](https://pubmed.ncbi.nlm.nih.gov/19918712/) Boswellia serrata extract, Boswellia serrata gum · Planta Medica, 2010
- [Enhancing the Cosmetic Potential of Aloe Vera Gel by Kombucha-Mediated Fermentation: Phytochemical Analysis and Evaluation of Antioxidant, Anti-Aging and Moisturizing Properties](https://pubmed.ncbi.nlm.nih.gov/40807366/) Saccharomyces xylinum black tea ferment · Molecules, 2025
- [Tocopherol succinate-loaded ethosomal gel synthesized by cold method technique: Deeper biophysical characterizations for translational application on human skin](https://pubmed.ncbi.nlm.nih.gov/38268219/) Vitamin e · Journal of Cosmetic Dermatology, 2024
- [The anti wrinkle efficacy of synthetic hexapeptide (Argireline) in Chinese Subjects](https://pubmed.ncbi.nlm.nih.gov/23607739/) Acetyl hexapeptide-8 · Journal of Cosmetic and Laser Therapy, 2013
- [Histometric assessment of the age-related skin response to 2-hydroxy-5-octanoyl benzoic acid](https://pubmed.ncbi.nlm.nih.gov/9603669/) Capryloyl salicylic acid · Skin Pharmacology and Applied Skin Physiology, 1998
- [Comparison of clindamycin 1% and benzoyl peroxide 5% gel to a novel composition containing salicylic acid, capryloyl salicylic acid, HEPES, glycolic acid, citric acid, and dioic acid in the treatment of acne vulgaris](https://pubmed.ncbi.nlm.nih.gov/23545907/) Capryloyl salicylic acid, Hydroxyethylpiperazine ethane sulfonic acid, Citric acid · Journal of Drugs in Dermatology, 2013
- [Functional properties and skin care effects of sodium trehalose sulfate](https://pubmed.ncbi.nlm.nih.gov/38606717/) Trehalose · Skin Research and Technology, 2024
- [Nanostructured Lipid Carrier Based Gel Containing α-Tocopherol and α-Tocopheryl Acetate for Synergistic Cutaneous Antiaging Efficacy](https://pubmed.ncbi.nlm.nih.gov/41309687/) Tocopheryl acetate · Scientific Reports, 2025
- [Evaluation of additive effects of hydrolyzed jojoba (Simmondsia chinensis) esters and glycerol: a preliminary study](https://pubmed.ncbi.nlm.nih.gov/19146603/) Jojoba esters · Journal of Cosmetic Dermatology, 2008
- [Peptide-pro complex serum: Investigating effects on aged skin](https://pubmed.ncbi.nlm.nih.gov/35426243/) Marine extracts · Journal of Cosmetic Dermatology, 2023
- [Green Synthesis of Copper Oxide Nanoparticles using Cucumis Sativus (Cucumber) Extracts and their Bio-Physical and Biochemical Characterization for Cosmetic and Dermatologic Applications](https://pubmed.ncbi.nlm.nih.gov/32628604/) Cucumis sativus fruit extract · Endocrine, Metabolic & Immune Disorders Drug Targets, 2021
- [Prospective randomized double-blind comparative study of topical acetyl zingerone with tetrahexyldecyl ascorbate versus tetrahexyldecyl ascorbate alone on facial photoaging](https://pubmed.ncbi.nlm.nih.gov/38525606/) Tetrahexyldecyl ascorbate · Journal of Cosmetic Dermatology, 2024
- [Effect of an Emollient Emulsion Containing 15.0% of Caprylic/Capric Triglyceride on the Urocanic Acid of the Stratum Corneum](https://pubmed.ncbi.nlm.nih.gov/37109405/) Caprylic capric triglyceride · Life, 2023
- [Clinical Efficacy of a Flavo-Proxylane Topical Regimen Pre- and Post-ultrasound Procedure for Subjects Undergoing Glucagon-Like Peptide 1 (GLP-1) Receptor Agonist Therapy](https://pubmed.ncbi.nlm.nih.gov/41781778/) Proxylane · Dermatology and Therapy, 2026
- [Safety assessment on comedogenicity of dermatological products containing d-alpha tocopheryl acetate in Asian subjects: A double-blind randomized controlled trial](https://pubmed.ncbi.nlm.nih.gov/34471722/) Tocopheryl acetate, Tocopheryl acetate vitamin e · Contemporary Clinical Trials Communications, 2021
- [A Randomized Controlled Trial of the Genistein Plus Bakuchiol and Vitamins (GEN+) Product for Male Facial Skin: Effects on Skin Appearance and Properties](https://pubmed.ncbi.nlm.nih.gov/41562471/) Bakuchiol · Skin Research and Technology, 2026
- [A polyhydroxy acid skin care regimen provides antiaging effects comparable to an alpha-hydroxyacid regimen](https://pubmed.ncbi.nlm.nih.gov/15002657/) Pha polyhydroxy acid · Cutis, 2004
- [The effect of a serum containing acetyl hexapeptide-8, dipeptide diaminobutyroyl benzylamide diacetate and gluconolactone on skin biomarkers, wrinkles and skin texture: Ex vivo and clinical studies](https://pubmed.ncbi.nlm.nih.gov/41668671/) Laminaria digitata extract · International Journal of Cosmetic Science, 2026
- [The Application of a Formulation Containing Hydroxypropyl Tetrahydropyrantriol and Niacinamide to Augment Anti-aging Benefits in a Double-blind, Randomized Nonablative Laser Treatment Study](https://pubmed.ncbi.nlm.nih.gov/41647767/) Proxylane · The Journal of Clinical and Aesthetic Dermatology, 2025
- [Clinical Evaluation of a Soap-Free Cleansing Lotion Containing Sodium Cocoyl Apple Amino Acids for Effective Impurity Removal and Skin Barrier Preservation in Healthy Adults With Diverse Skin Types](https://pubmed.ncbi.nlm.nih.gov/40978887/) Cetyl alcohol · Cureus, 2025
- [Mechanistic understanding and peptide ingredient screening for type III collagen via biological knowledge graph and molecular docking](https://pubmed.ncbi.nlm.nih.gov/42683869/) Palmitoyl oligopeptide · International Journal of Cosmetic Science, 2026
- [The Therapeutic Effects of a Bentonite-Based Facial Mask With Alcea sulphurea Extract on Acne Severity and Patient Experience: Add-On Randomized Controlled Clinical Trial](https://pubmed.ncbi.nlm.nih.gov/41347526/) Bentonite · Journal of Cosmetic Dermatology, 2025
- [Targeting Circadian Rhythm for the Regulation of Skin Collagen Metabolism](https://pubmed.ncbi.nlm.nih.gov/41527525/) Palmitoyl tripeptide-1 · Journal of Cosmetic Dermatology, 2026
- [Prospective, Randomized, Double-Blind Assessment of Supramolecular Bakuchiol and Terminalia Chebula Extract for Facial Photoaging in Chinese Sensitive Skin Population](https://pubmed.ncbi.nlm.nih.gov/41424674/) Bakuchiol · Health Science Reports, 2025
- [Split-face evaluation: Gluconolactone plus oxybrasion versus gluconolactone plus microneedling. The effects on skin parameters](https://pubmed.ncbi.nlm.nih.gov/37357656/) Gluconolactone · Skin Research and Technology, 2023
- [Efficacy and safety of combination cream of stimu-tex AS™ (spent grain wax, Argania Spinosa Kernel oil, Butyrospermum Parkii (shea butter) extract), and saccharide isomerate after fractional CO2 laser procedure: split-face, double blinded, randomized controlled trial](https://pubmed.ncbi.nlm.nih.gov/41134387/) Shea butter · Lasers in Medical Science, 2025
- [Preclinical Safety Evaluation of Dual Drug-Loaded Nanolipidic Carriers of Dissolvable Patches: In-Vitro and In-Vivo Safety Assessment](https://pubmed.ncbi.nlm.nih.gov/41186117/) Tetrahydrodiferuloylmethane · Molecular Pharmaceutics, 2025
- [Acai Oil-Based Organogel Containing Hyaluronic Acid for Topical Cosmetic: In Vitro and Ex Vivo Assessment](https://pubmed.ncbi.nlm.nih.gov/39339231/) Euterpe oleracea fruit extract · Pharmaceutics, 2024

## The brands

- American skincare: [SkinCeuticals](https://lovi.care/skincare/sg/brands/skinceuticals)
- British skincare: [Medik8](https://lovi.care/skincare/sg/brands/medik8)

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## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this comparison: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

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