# Sesderma vs grace & stella

Page: https://lovi.care/skincare/sg/compare/sesderma-vs-grace-and-stella

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Singapore.

Sesderma and grace & stella are two distinct skincare lines offering targeted solutions for diverse complexions. The Spanish brand is known for advanced [serums](https://lovi.care/skincare/sg/ingredients/serum) with botanical [extracts](https://lovi.care/skincare/sg/ingredients/extract) and active compounds, suiting sensitive, hyperpigmented, and aging skin types best. Conversely, the Canadian brand is loved for nourishing eye products and moisturizers that suit all skin types best. While both feature carefully crafted formulas to refine texture, they differ in their primary focuses and key ingredients.

Sesderma is a Spanish skincare brand founded in 1989 and owned by Grupo Sesderma since 2026.

[skinexpert.sesderma.com](https://skinexpert.sesderma.com/en/jb-capital-joins-the-shareholding-of-sesderma-group-as-a-strategic-partner/) [sesderma.com](https://www.sesderma.com/us_en/about-us.html)

grace & stella is a Canadian skincare brand founded in 2016 and owned by Gravitiq since 2022.

[graceandstella.com](https://www.graceandstella.com/pages/faq) [tracxn.com](https://tracxn.com/d/companies/gravitiq/__cAcLAYVXizPoeM7P-lpcSTukNbDz1463zb8cbxeIerY) [pitchbook.com](https://pitchbook.com/profiles/company/484071-94) [preqin.com](https://www.preqin.com/data/profile/asset/gravitiq-holdings--inc-/454659)

This page compares some of the most popular Sesderma and grace & stella products; for every product of both brands, with a fit score for your own skin, [use the Lovi app](https://app.pora.ai/vqqJ/j1xj2b6o?af_sub2=compare&af_sub3=selection_note&af_sub4=pg070b63022d).

### Popular Sesderma vs grace & stella products

#### grace & stella

- [Under Eye Mask](https://lovi.care/skincare/sg/p/grace-and-stella/under-eye-mask/for/oily-skin) — Superior fit
- [Hyaluronic Acid Serum](https://lovi.care/skincare/sg/p/grace-and-stella/hyaluronic-acid-serum/for/dry-sensitive-skin) — High fit

#### Sesderma

- [Azelac RU Serum](https://lovi.care/skincare/sg/p/sesderma/azelac-ru-serum/for/acne-prone-skin) — High fit

## Questions and answers

### Sesderma or grace & stella: which is better?

grace & stella fits a wider variety of skin types better across the products on this page, and every product lists no fragrance. Sesderma's Azelac RU [Serum](https://lovi.care/skincare/sg/ingredients/serum) achieves a High fit for acne-prone skin and dark spots, though it contains fragrance.

[Pharmaceutics, 2021](https://pubmed.ncbi.nlm.nih.gov/33923739/)

### What is the difference between Sesderma and grace & stella?

grace & stella wins out for most skin types on this page, as Lovi rates its Under Eye Mask and [Hyaluronic Acid](https://lovi.care/skincare/sg/ingredients/hyaluronic-acid) Serum at High to Superior fits across almost all skin types, while Sesderma features only Azelac RU Serum with High fit levels limited to acne-prone, dark spot, and combination skin. Additionally, all products on this page from grace & stella list no fragrance, whereas Sesderma includes fragrance in its serum.

### Which is more affordable, Sesderma or grace & stella?

The provided page facts and studies do not contain pricing information, so it is not possible to determine whether Sesderma or grace & stella is more affordable.

### Which causes fewer breakouts, Sesderma or grace & stella?

grace & stella fits acne-prone skin with a High Lovi rating across the products on this page, whereas Sesderma scores High for acne-prone skin but only Average for oily acne-prone skin. Topical [azelaic acid](https://lovi.care/skincare/sg/ingredients/azelaic-acid) helps manage acne vulgaris.

[Pharmaceutics, 2021](https://pubmed.ncbi.nlm.nih.gov/33923739/)

### Which brand has been established longer, Sesderma or grace & stella?

Sesderma has been established longer, having been founded in Spain in 1989 compared to grace & stella, which was founded in Canada in 2016.

### Do products from Sesderma or grace & stella contain fragrance?

Grace & stella offers fragrance-free choices, as every product on this page lists no fragrance in its ingredients. Sesderma includes fragrance in its Azelac RU Serum, meaning 0 of 1 products on this page list no fragrance.

### Which brand offers an eye product on this page?

grace & stella offers an eye product on this page called Under Eye Mask. Sesderma does not list any eye products among the products on this page.

## Research behind their key ingredients

- [Vitamin A antagonizes decreased cell growth and elevated collagen-degrading matrix metalloproteinases and stimulates collagen accumulation in naturally aged human skin](https://pubmed.ncbi.nlm.nih.gov/10692106/) Retinol · The Journal of Investigative Dermatology, 2000
- [The effect of niacinamide on reducing cutaneous pigmentation and suppression of melanosome transfer](https://pubmed.ncbi.nlm.nih.gov/12100180/) Niacinamide · The British Journal of Dermatology, 2002
- [Benefits of topical hyaluronic acid for skin quality and signs of skin aging: From literature review to clinical evidence](https://pubmed.ncbi.nlm.nih.gov/36200921/) Sodium hyaluronate · Dermatologic Therapy, 2022
- [Topical use of dexpanthenol in skin disorders](https://pubmed.ncbi.nlm.nih.gov/12113650/) Panthenol · American Journal of Clinical Dermatology, 2002
- [Improvement of naturally aged skin with vitamin A (retinol)](https://pubmed.ncbi.nlm.nih.gov/17515510/) Retinol · Archives of Dermatology, 2007
- [Nicotinic acid/niacinamide and the skin](https://pubmed.ncbi.nlm.nih.gov/17147561/) Niacin · Journal of Cosmetic Dermatology, 2004
- [Molecular basis of retinol anti-ageing properties in naturally aged human skin in vivo](https://pubmed.ncbi.nlm.nih.gov/27261203/) Retinol · International Journal of Cosmetic Science, 2017
- [Prospective, randomized, double-blind assessment of topical bakuchiol and retinol for facial photoageing](https://pubmed.ncbi.nlm.nih.gov/29947134/) Retinol · The British Journal of Dermatology, 2019
- [Efficacy and Safety of Azelaic Acid Nanocrystal-Loaded In Situ Hydrogel in the Treatment of Acne Vulgaris](https://pubmed.ncbi.nlm.nih.gov/33923739/) Azelaic acid · Pharmaceutics, 2021
- [A topical lipophilic niacin derivative increases NAD, epidermal differentiation and barrier function in photodamaged skin](https://pubmed.ncbi.nlm.nih.gov/17518989/) Niacin · Experimental Dermatology, 2007
- [The 24-hour skin hydration and barrier function effects of a hyaluronic 1%, glycerin 5%, and Centella asiatica stem cells extract moisturizing fluid: an intra-subject, randomized, assessor-blinded study](https://pubmed.ncbi.nlm.nih.gov/28860834/) Glycerin · Clinical, Cosmetic and Investigational Dermatology, 2017
- [A new topical panthenol-containing emollient: Results from two randomized controlled studies assessing its skin moisturization and barrier restoration potential, and the effect on skin microflora](https://pubmed.ncbi.nlm.nih.gov/27425824/) Panthenol · The Journal of Dermatological Treatment, 2017
- [Effects of 15% Azelaic Acid Gel in the Management of Post-Inflammatory Erythema and Post-Inflammatory Hyperpigmentation in Acne Vulgaris](https://pubmed.ncbi.nlm.nih.gov/38734843/) Azelaic acid · Dermatology and Therapy, 2024
- [Influence of vitamin E acetate on stratum corneum hydration](https://pubmed.ncbi.nlm.nih.gov/9706379/) Tocopheryl acetate · Arzneimittel-Forschung, 1998
- [Evaluation of the Efficacy and Safety of a Panthenol-Enriched Mask for Skin Barrier Recovery After Facial Laser Treatment: Results of a Double-Blind Randomized Controlled Study](https://pubmed.ncbi.nlm.nih.gov/40613435/) Panthenol · Journal of Cosmetic Dermatology, 2025
- [Nanostructured Lipid Carrier Based Gel Containing α-Tocopherol and α-Tocopheryl Acetate for Synergistic Cutaneous Antiaging Efficacy](https://pubmed.ncbi.nlm.nih.gov/41309687/) Tocopheryl acetate · Scientific Reports, 2025
- [Functional properties and skin care effects of sodium trehalose sulfate](https://pubmed.ncbi.nlm.nih.gov/38606717/) Trehalose · Skin Research and Technology, 2024
- [Safety assessment on comedogenicity of dermatological products containing d-alpha tocopheryl acetate in Asian subjects: A double-blind randomized controlled trial](https://pubmed.ncbi.nlm.nih.gov/34471722/) Tocopheryl acetate · Contemporary Clinical Trials Communications, 2021
- [The efficacy of enoxolone in reducing erythema and pain after laser treatment: A randomized split-face pilot study](https://pubmed.ncbi.nlm.nih.gov/38622995/) Glycyrrhetinic acid · Journal of Cosmetic Dermatology, 2024

## The brands

- Spanish skincare: [Sesderma](https://lovi.care/skincare/sg/brands/sesderma)
- Canadian skincare: [grace & stella](https://lovi.care/skincare/sg/brands/grace-and-stella)

## More comparisons

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- [SKIN1004 vs grace & stella](https://lovi.care/skincare/sg/compare/skin1004-vs-grace-and-stella)
- [Anua vs Sesderma](https://lovi.care/skincare/sg/compare/anua-vs-sesderma)
- [Anua vs grace & stella](https://lovi.care/skincare/sg/compare/anua-vs-grace-and-stella)
- [Medicube vs Sesderma](https://lovi.care/skincare/sg/compare/medicube-vs-sesderma)
- [Medicube vs grace & stella](https://lovi.care/skincare/sg/compare/medicube-vs-grace-and-stella)
- [The Ordinary vs Sesderma](https://lovi.care/skincare/sg/compare/the-ordinary-vs-sesderma)
- [The Ordinary vs grace & stella](https://lovi.care/skincare/sg/compare/the-ordinary-vs-grace-and-stella)
- [Beauty of Joseon vs Sesderma](https://lovi.care/skincare/sg/compare/beauty-of-joseon-vs-sesderma)
- [Beauty of Joseon vs grace & stella](https://lovi.care/skincare/sg/compare/beauty-of-joseon-vs-grace-and-stella)
- [COSRX vs Sesderma](https://lovi.care/skincare/sg/compare/cosrx-vs-sesderma)
- [COSRX vs grace & stella](https://lovi.care/skincare/sg/compare/cosrx-vs-grace-and-stella)
- [CeraVe vs Sesderma](https://lovi.care/skincare/sg/compare/cerave-vs-sesderma)
- [CeraVe vs grace & stella](https://lovi.care/skincare/sg/compare/cerave-vs-grace-and-stella)
- [La Roche-Posay vs Sesderma](https://lovi.care/skincare/sg/compare/la-roche-posay-vs-sesderma)
- [La Roche-Posay vs grace & stella](https://lovi.care/skincare/sg/compare/la-roche-posay-vs-grace-and-stella)
- [Dr. Althea vs Sesderma](https://lovi.care/skincare/sg/compare/dr-althea-vs-sesderma)
- [Dr. Althea vs grace & stella](https://lovi.care/skincare/sg/compare/dr-althea-vs-grace-and-stella)
- [Some By Mi vs Sesderma](https://lovi.care/skincare/sg/compare/some-by-mi-vs-sesderma)
- [Some By Mi vs grace & stella](https://lovi.care/skincare/sg/compare/some-by-mi-vs-grace-and-stella)

## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this comparison: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/compare/sesderma-vs-grace-and-stella
- United Kingdom: https://lovi.care/skincare/uk/compare/sesderma-vs-grace-and-stella
- Ireland: https://lovi.care/skincare/ie/compare/sesderma-vs-grace-and-stella
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- Netherlands: https://lovi.care/skincare/nl/compare/sesderma-vs-grace-and-stella
- Spain: https://lovi.care/skincare/es/compare/sesderma-vs-grace-and-stella
- Canada: https://lovi.care/skincare/ca/compare/sesderma-vs-grace-and-stella
- Australia: https://lovi.care/skincare/au/compare/sesderma-vs-grace-and-stella
- Singapore: https://lovi.care/skincare/sg/compare/sesderma-vs-grace-and-stella (this page)
- Saudi Arabia: https://lovi.care/skincare/sa/compare/sesderma-vs-grace-and-stella
- United Arab Emirates: https://lovi.care/skincare/ae/compare/sesderma-vs-grace-and-stella
