# Neutrogena vs ISDIN

Page: https://lovi.care/skincare/sg/compare/neutrogena-vs-isdin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Singapore.

Neutrogena and ISDIN are well-regarded skincare brands that offer reliable daily support for a healthy complexion. Neutrogena is universally loved for its thoughtful array of moisturizers, sunscreens, cleansers, and toners formulated with [glycerin](https://lovi.care/skincare/sg/ingredients/glycerin), [hyaluronic acid](https://lovi.care/skincare/sg/ingredients/hyaluronic-acid), and [dimethicone](https://lovi.care/skincare/sg/ingredients/dimethicone), which suit sensitive skin and mature skin best. Meanwhile, the Spanish brand is known for its elegant moisturizers, advanced sunscreens, restorative [serums](https://lovi.care/skincare/sg/ingredients/serum), and targeted eye products that suit dry skin and sensitive skin best. While both provide gentle comfort and targeted solutions for various concerns, they differ in their heritage, specific formulations, and primary focus areas.

Neutrogena is an American skincare brand founded in 1930 and owned by Kimberly-Clark Corporation since 2026.

[investor.kimberly-clark.com](https://www.investor.kimberly-clark.com/news-releases/news-release-details/kimberly-clark-completes-acquisition-kenvue-creating-preeminent) [en.wikipedia.org](https://en.wikipedia.org/wiki/Neutrogena) [investors.kenvue.com](https://investors.kenvue.com/financial-news/news-details/2025/Kimberly-Clark-to-Acquire-Kenvue-Creating-a-32-Billion-Global-Health-and-Wellness-Leader/default.aspx)

ISDIN is a Spanish skincare brand founded in 1975 and owned by Puig.

[puig.com](https://www.puig.com/en/newsroom/new-chapter-for-Isdin-Puig-to-assume-full-ownership/) [beautymatter.com](https://beautymatter.com/articles/puig-to-take-full-ownership-of-isdin-in-1-39-billion-deal) [uploads.puig.com](https://uploads.puig.com/uploads/Puig_NP_Sept_14_EN_fc21e2f47a.pdf)

This page compares some of the most popular Neutrogena and ISDIN products; for every product of both brands, with a fit score for your own skin, [use the Lovi app](https://app.pora.ai/vqqJ/j1xj2b6o?af_sub2=compare&af_sub3=selection_note&af_sub4=pg5ec52ea3d1).

### Popular Neutrogena vs ISDIN products

#### ISDIN

- [Eryfotona Actinica](https://lovi.care/skincare/sg/p/isdin/eryfotona-actinica/for/mature-skin) — Superior fit — [S$110.01 at Amazon](https://www.amazon.sg/dp/B07RXS4FQM?tag=lovi-care-web-product0e-22&linkCode=osi&th=1&psc=1)
- [Fusion Water](https://lovi.care/skincare/sg/p/isdin/fusion-water/for/dry-sensitive-skin) — Superior fit
- [K-Ox Eyes](https://lovi.care/skincare/sg/p/isdin/k-ox-eyes/for/dry-skin) — High fit
- [Hyaluronic Concentrate](https://lovi.care/skincare/sg/p/isdin/hyaluronic-concentrate/for/sensitive-skin) — High fit
- [Hyaluronic Moisture](https://lovi.care/skincare/sg/p/isdin/hyaluronic-moisture/for/dry-sensitive-skin) — Average fit
- [Flavo-C Serum](https://lovi.care/skincare/sg/p/isdin/flavo-c-serum/for/sensitive-skin) — High fit — [S$161.49 at Amazon](https://www.amazon.sg/dp/B01BMLQ086?tag=lovi-care-web-product0e-22&linkCode=osi&th=1&psc=1)
- [Uradin Lotion 10](https://lovi.care/skincare/sg/p/isdin/uradin-lotion-10/for/dry-skin) — High fit
- [Retinal Intense Serum](https://lovi.care/skincare/sg/p/isdin/retinal-intense-serum/for/acne-prone-skin) — High fit

#### Neutrogena

- [Hydro Boost Water Gel](https://lovi.care/skincare/sg/p/neutrogena/hydro-boost-water-gel/for/sensitive-skin) — Average fit — [S$28.51 at Amazon](https://www.amazon.sg/dp/B0CX3CCJWV?tag=lovi-care-web-product0e-22&linkCode=osi&th=1&psc=1)
- [Ultra Sheer Dry-Touch Sunscreen](https://lovi.care/skincare/sg/p/neutrogena/ultra-sheer-dry-touch-sunscreen/for/combination-skin) — Superior fit — [S$28.35 at Amazon](https://www.amazon.sg/dp/B004D2DR0Q?tag=lovi-care-web-product0e-22&linkCode=osi&th=1&psc=1)
- [HYDRO BOOST WATER CREAM](https://lovi.care/skincare/sg/p/neutrogena/hydro-boost-water-cream/for/dry-skin) — Superior fit — [S$28.51 at Amazon](https://www.amazon.sg/dp/B0CX3CCJWV?tag=lovi-care-web-product0e-22&linkCode=osi&th=1&psc=1)
- [Ultra Gentle Daily Cleanser](https://lovi.care/skincare/sg/p/neutrogena/ultra-gentle-daily-cleanser/for/mature-skin) — Superior fit — [S$82.61 at Amazon](https://www.amazon.sg/dp/B08CSLHGL2?tag=lovi-care-web-product0e-22&linkCode=osi&th=1&psc=1)
- [Rapid Wrinkle Repair Regenerating Cream](https://lovi.care/skincare/sg/p/neutrogena/rapid-wrinkle-repair-regenerating-cream/for/mature-skin) — High fit — [S$36.58 at Amazon](https://www.amazon.sg/dp/B0725JP4TN?tag=lovi-care-web-product0e-22&linkCode=osi&th=1&psc=1)
- [Oil-Free Eye Makeup Remover](https://lovi.care/skincare/sg/p/neutrogena/oil-free-eye-makeup-remover/for/dark-spots) — Superior fit — [S$17.59 at Amazon](https://www.amazon.sg/dp/B07T9JV956?tag=lovi-care-web-product0e-22&linkCode=osi&th=1&psc=1)
- [Retinol Regenerating Cream](https://lovi.care/skincare/sg/p/neutrogena/retinol-regenerating-cream/for/mature-skin) — Average fit
- [COLLAGEN BANK Moisturizer](https://lovi.care/skincare/sg/p/neutrogena/collagen-bank-moisturizer/for/dry-skin) — Average fit — [S$28.16 at Amazon](https://www.amazon.sg/dp/B0D43JLX7H?tag=lovi-care-web-product0e-22&linkCode=osi&th=1&psc=1)

## People Say

Neutrogena

ISDIN

- Lightweight and non-greasy texture Mostly Mentioned Mostly Mentioned “absorbs instantly — ISDIN Eryfotona Actinica” “ultra-light fluid product, which makes it super easy to apply — ISDIN Fusion Water” “Lightweight formula absorbs fast — ISDIN Hyaluronic Concentrate” “Absorbs instantly without sticky residue — Neutrogena Hydro Boost Water Gel”
- Deep hydration and moisture Mostly Mentioned Mostly Mentioned “Skin looked plumper and radiant — Neutrogena HYDRO BOOST WATER CREAM” “It also hydrates my skin. This cream has been so easy to add to my routine. — Neutrogena Retinol Regenerating Cream” “Improved moisture and texture — ISDIN Hyaluronic Moisture” “skin looks smooth and healthy — ISDIN K-Ox Eyes”
- Sensitive skin friendly and gentle Mostly Mentioned Often Mentioned “leaves skin soft and balanced — Neutrogena Ultra Gentle Daily Cleanser” “love that it has no scent — Neutrogena Ultra Gentle Daily Cleanser” “Sensitive/reactive skin tolerates — ISDIN Hyaluronic Moisture” “no excessive exfoliation — ISDIN Retinal Intense Serum”
- Makeup compatibility and base Sometimes Noted Often Mentioned “Foundation glides right over it — Neutrogena Hydro Boost Water Gel” “Concealer doesn't cake or get stuck in crevices — Neutrogena Hydro Boost Eye Gel-Cream” “acts like a primer — ISDIN Eryfotona Actinica” “My skin felt sooo hydrated and looks so plump and dewey. — ISDIN Fusion Water”
- Skin texture improvement and anti-aging Sometimes Noted Rarely Noted “Skin is looking smoother — Neutrogena Rapid Wrinkle Repair Regenerating Cream” “Deep lines have softened — Neutrogena Rapid Wrinkle Repair Regenerating Cream” “I can see a difference in my forehead wrinkles. — Neutrogena Retinol Regenerating Cream” “skin was much smoother — ISDIN Retinal Intense Serum”
- Cooling and soothing sensation Rarely Noted Sometimes Noted “Feels amazing and cold on the skin — Neutrogena Hydro Boost Hydrating Hydrogel Mask” “Feels refreshing and cool on application — Neutrogena Hydro Boost Water Gel” “applicator has a cooling effect — ISDIN K-Ox Eyes”
- Price vs quantity and high cost Sometimes Noted Often Mentioned “Jar is too small for the price — Neutrogena Hydro Boost Water Gel” “Runs out quickly — Neutrogena HYDRO BOOST WATER CREAM” “Tube is tiny for the cost — Neutrogena Hydro Boost Eye Gel-Cream” “very expensive — ISDIN Eryfotona Actinica”
- Strong fragrance and scent issues Sometimes Noted Often Mentioned “Smell is too overpowering and lingering — Neutrogena Hydro Boost Water Gel” “Scent is so off-putting — Neutrogena Rapid Wrinkle Repair Regenerating Cream” “smell is overpowering — ISDIN Eryfotona Actinica” “lingering headache inducing effect — ISDIN K-Ox Eyes”
- Packaging and design issues Sometimes Noted Rarely Noted “Pump stopped working — ISDIN Hyaluronic Concentrate” “I like the actual product, but the packaging is awful, I've already lost three bottles the applicator pops off. — ISDIN Flavo-C Serum” “Eye holes are too small — Neutrogena Hydro Boost Hydrating Hydrogel Mask”

### Neutrogena vs ISDIN routines for dry skin

#### ISDIN-focused routine

- Cleanser: [CeraVe Hydrating Facial Cleanser](https://lovi.care/skincare/sg/p/cerave/hydrating-facial-cleanser/for/dry-skin) — Superior fit — [S$25.06 at Amazon](https://www.amazon.sg/dp/B07RL88DD2?tag=lovi-care-web-routine07-22&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- Hydrating Toner: [COSRX Propolis Synergy Toner](https://lovi.care/skincare/sg/p/cosrx/propolis-synergy-toner/for/dry-skin) — Superior fit — [S$41.07 at Amazon](https://www.amazon.sg/dp/B07XHHRXDZ?tag=lovi-care-web-routine07-22&linkCode=osi&th=1&psc=1) — Morning
- Moisturizer: [d'Alba First Spray Serum](https://lovi.care/skincare/sg/p/d-alba/first-spray-serum/for/dry-skin) — Superior fit — [S$25.94 at Amazon](https://www.amazon.sg/dp/B0C5T25JJP?tag=lovi-care-web-routine07-22&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- SPF: [Eryfotona Actinica](https://lovi.care/skincare/sg/p/isdin/eryfotona-actinica/for/dry-skin) — High fit — [S$110.01 at Amazon](https://www.amazon.sg/dp/B07RXS4FQM?tag=lovi-care-web-routine07-22&linkCode=osi&th=1&psc=1) — Morning
- Pre-Cleanser: [MISSHA Ultra Hyalon Cleansing Cream](https://lovi.care/skincare/sg/p/missha/ultra-hyalon-cleansing-cream/for/dry-skin) — Superior fit — [S$39.68 at Amazon](https://www.amazon.sg/dp/B084Q16G8D?tag=lovi-care-web-routine07-22&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Serum or Treatment: [Flavo-C Serum](https://lovi.care/skincare/sg/p/isdin/flavo-c-serum/for/dry-skin) — Average fit — [S$161.49 at Amazon](https://www.amazon.sg/dp/B01BMLQ086?tag=lovi-care-web-routine07-22&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Nourishing Mask: [MEDIHEAL Collagen Essential Mask](https://lovi.care/skincare/sg/p/mediheal/collagen-essential-mask/for/dry-skin) — Superior fit — [S$62.94 at Amazon](https://www.amazon.sg/dp/B0DDBDYZWN?tag=lovi-care-web-routine07-22&linkCode=osi&th=1&psc=1) — Once a week

#### Neutrogena-focused routine

- Cleanser: [Hydro Boost Water Gel](https://lovi.care/skincare/sg/p/neutrogena/hydro-boost-water-gel/for/dry-skin) — Average fit — [S$28.51 at Amazon](https://www.amazon.sg/dp/B0CX3CCJWV?tag=lovi-care-web-routine07-22&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- Hydrating Toner: [Alcohol-Free Toner](https://lovi.care/skincare/sg/p/neutrogena/alcohol-free-toner/for/dry-skin) — High fit — [S$67.90 at Amazon](https://www.amazon.sg/dp/B01LTI056U?tag=lovi-care-web-routine07-22&linkCode=osi&th=1&psc=1) — Morning
- Moisturizer: [Hydro Boost Hyaluronic Acid Serum](https://lovi.care/skincare/sg/p/neutrogena/hydro-boost-hyaluronic-acid-serum/for/dry-skin) — Superior fit — [S$31.79 at Amazon](https://www.amazon.sg/dp/B01HOHBS7K?tag=lovi-care-web-routine07-22&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- SPF: [Clear Face Liquid Lotion Sunscreen](https://lovi.care/skincare/sg/p/neutrogena/clear-face-liquid-lotion-sunscreen/for/dry-skin) — Average fit — [S$16.08 at Amazon](https://www.amazon.sg/dp/B004D2C5FY?tag=lovi-care-web-routine07-22&linkCode=osi&th=1&psc=1) — Morning
- Pre-Cleanser: [HYDRO BOOST WATER CREAM](https://lovi.care/skincare/sg/p/neutrogena/hydro-boost-water-cream/for/dry-skin) — Superior fit — [S$28.51 at Amazon](https://www.amazon.sg/dp/B0CX3CCJWV?tag=lovi-care-web-routine07-22&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Serum or Treatment: [Peach & Lily Glass Skin Refining Serum](https://lovi.care/skincare/sg/p/peach-and-lily/glass-skin-refining-serum/for/dry-skin) — Superior fit — [S$63.44 at Amazon](https://www.amazon.sg/dp/B08H4QPM19?tag=lovi-care-web-routine07-22&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Nourishing Mask: [Hydro Boost Hydrating Hydrogel Mask](https://lovi.care/skincare/sg/p/neutrogena/hydro-boost-hydrating-hydrogel-mask/for/dry-skin) — High fit — [S$57.28 at Amazon](https://www.amazon.sg/dp/B076H45H68?tag=lovi-care-web-routine07-22&linkCode=osi&th=1&psc=1) — Once a week

[Buy ISDIN routine · S$466.19 · 93% fit](https://www.amazon.sg/gp/aws/cart/add.html?ASIN.1=B07RL88DD2&Quantity.1=1&ASIN.2=B07XHHRXDZ&Quantity.2=1&ASIN.3=B0C5T25JJP&Quantity.3=1&ASIN.4=B07RXS4FQM&Quantity.4=1&ASIN.5=B084Q16G8D&Quantity.5=1&ASIN.6=B01BMLQ086&Quantity.6=1&ASIN.7=B0DDBDYZWN&Quantity.7=1&AssociateTag=lovi-care-web-routine07-22) [Buy Neutrogena routine · S$265.00 · 82% fit](https://www.amazon.sg/gp/aws/cart/add.html?ASIN.1=B0CX3CCJWV&Quantity.1=1&ASIN.2=B01LTI056U&Quantity.2=1&ASIN.3=B01HOHBS7K&Quantity.3=1&ASIN.4=B004D2C5FY&Quantity.4=1&ASIN.5=B08H4QPM19&Quantity.5=1&ASIN.6=B076H45H68&Quantity.6=1&AssociateTag=lovi-care-web-routine07-22) [See multi-brand routine · 99% fit](https://lovi.care/skincare/sg/skin/dry-skin)

### Neutrogena vs ISDIN routines for oily skin

#### ISDIN-focused routine

- Cleanser: [CeraVe Foaming Facial Cleanser](https://lovi.care/skincare/sg/p/cerave/foaming-facial-cleanser/for/oily-skin) — Superior fit — [S$30.40 at Amazon](https://www.amazon.sg/dp/B07RJ18VMF?tag=lovi-care-web-routine07-22&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- Hydrating Toner: [TROIAREUKE H+Cocktail Purifying Ampoule Toner](https://lovi.care/skincare/sg/p/troiareuke/h-cocktail-purifying-ampoule-toner/for/oily-skin) — Superior fit — [S$168.51 at Amazon](https://www.amazon.sg/dp/B00S7GMF02?tag=lovi-care-web-routine07-22&linkCode=osi&th=1&psc=1) — Morning · Once a week
- Moisturizer: [SKIN1004 Centella Cream](https://lovi.care/skincare/sg/p/skin1004/centella-cream/for/oily-skin) — Superior fit — [S$33.87 at Amazon](https://www.amazon.sg/dp/B0C8SBJD89?tag=lovi-care-web-routine07-22&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- SPF: [Eryfotona Actinica](https://lovi.care/skincare/sg/p/isdin/eryfotona-actinica/for/oily-skin) — High fit — [S$110.01 at Amazon](https://www.amazon.sg/dp/B07RXS4FQM?tag=lovi-care-web-routine07-22&linkCode=osi&th=1&psc=1) — Morning
- Pre-Cleanser: [Shu Uemura Ultime8 Sublime Beauty Cleansing Oil](https://lovi.care/skincare/sg/p/shu-uemura/ultime8-sublime-beauty-cleansing-oil/for/oily-skin) — Superior fit — [S$70.21 at Amazon](https://www.amazon.sg/dp/B0DNJKPSB8?tag=lovi-care-web-routine07-22&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Cleansing Toner: [Medicube Zero Pore Pad 2.0](https://lovi.care/skincare/sg/p/medicube/zero-pore-pad-2-0/for/oily-skin) — Superior fit — [S$36.48 at Amazon](https://www.amazon.sg/dp/B0CV7RX6ML?tag=lovi-care-web-routine07-22&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Serum or Treatment: [Flavo-C Serum](https://lovi.care/skincare/sg/p/isdin/flavo-c-serum/for/oily-skin) — High fit — [S$161.49 at Amazon](https://www.amazon.sg/dp/B01BMLQ086?tag=lovi-care-web-routine07-22&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Cleansing Mask: [HERBIVORE Botanicals Blue Tansy BHA and Enzyme Pore Refining Mask](https://lovi.care/skincare/sg/p/herbivore-botanicals/blue-tansy-bha-and-enzyme-pore-refining-mask/for/oily-skin) — Superior fit — [S$89.14 at Amazon](https://www.amazon.sg/dp/B015RRNQCY?tag=lovi-care-web-routine07-22&linkCode=osi&th=1&psc=1) — Once a week

#### Neutrogena-focused routine

- Cleanser: [Hydro Boost Water Gel](https://lovi.care/skincare/sg/p/neutrogena/hydro-boost-water-gel/for/oily-skin) — Caution fit — [S$28.51 at Amazon](https://www.amazon.sg/dp/B0CX3CCJWV?tag=lovi-care-web-routine07-22&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- Hydrating Toner: [Alcohol-Free Toner](https://lovi.care/skincare/sg/p/neutrogena/alcohol-free-toner/for/oily-skin) — Average fit — [S$67.90 at Amazon](https://www.amazon.sg/dp/B01LTI056U?tag=lovi-care-web-routine07-22&linkCode=osi&th=1&psc=1) — Morning · Once a week
- Moisturizer: [Hydro Boost+ Niacinamide Serum](https://lovi.care/skincare/sg/p/neutrogena/hydro-boost-niacinamide-serum/for/oily-skin) — High fit — [S$26.64 at Amazon](https://www.amazon.sg/dp/B0B3C3TJBF?tag=lovi-care-web-routine07-22&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- SPF: [Clear Face Liquid Lotion Sunscreen](https://lovi.care/skincare/sg/p/neutrogena/clear-face-liquid-lotion-sunscreen/for/oily-skin) — Superior fit — [S$16.08 at Amazon](https://www.amazon.sg/dp/B004D2C5FY?tag=lovi-care-web-routine07-22&linkCode=osi&th=1&psc=1) — Morning
- Pre-Cleanser: [Oil-Free Eye Makeup Remover](https://lovi.care/skincare/sg/p/neutrogena/oil-free-eye-makeup-remover/for/oily-skin) — Average fit — [S$17.59 at Amazon](https://www.amazon.sg/dp/B07T9JV956?tag=lovi-care-web-routine07-22&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Cleansing Toner: [Medicube Zero Pore Pad 2.0](https://lovi.care/skincare/sg/p/medicube/zero-pore-pad-2-0/for/oily-skin) — Superior fit — [S$36.48 at Amazon](https://www.amazon.sg/dp/B0CV7RX6ML?tag=lovi-care-web-routine07-22&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Serum or Treatment: [Peach & Lily Glass Skin Refining Serum](https://lovi.care/skincare/sg/p/peach-and-lily/glass-skin-refining-serum/for/oily-skin) — Superior fit — [S$63.44 at Amazon](https://www.amazon.sg/dp/B08H4QPM19?tag=lovi-care-web-routine07-22&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Cleansing Mask: [HERBIVORE Botanicals Blue Tansy BHA and Enzyme Pore Refining Mask](https://lovi.care/skincare/sg/p/herbivore-botanicals/blue-tansy-bha-and-enzyme-pore-refining-mask/for/oily-skin) — Superior fit — [S$89.14 at Amazon](https://www.amazon.sg/dp/B015RRNQCY?tag=lovi-care-web-routine07-22&linkCode=osi&th=1&psc=1) — Once a week

[Buy ISDIN routine · S$700.11 · 91% fit](https://www.amazon.sg/gp/aws/cart/add.html?ASIN.1=B07RJ18VMF&Quantity.1=1&ASIN.2=B00S7GMF02&Quantity.2=1&ASIN.3=B0C8SBJD89&Quantity.3=1&ASIN.4=B07RXS4FQM&Quantity.4=1&ASIN.5=B0DNJKPSB8&Quantity.5=1&ASIN.6=B0CV7RX6ML&Quantity.6=1&ASIN.7=B01BMLQ086&Quantity.7=1&ASIN.8=B015RRNQCY&Quantity.8=1&AssociateTag=lovi-care-web-routine07-22) [Buy Neutrogena routine · S$345.78 · 77% fit](https://www.amazon.sg/gp/aws/cart/add.html?ASIN.1=B0CX3CCJWV&Quantity.1=1&ASIN.2=B01LTI056U&Quantity.2=1&ASIN.3=B0B3C3TJBF&Quantity.3=1&ASIN.4=B004D2C5FY&Quantity.4=1&ASIN.5=B07T9JV956&Quantity.5=1&ASIN.6=B0CV7RX6ML&Quantity.6=1&ASIN.7=B08H4QPM19&Quantity.7=1&ASIN.8=B015RRNQCY&Quantity.8=1&AssociateTag=lovi-care-web-routine07-22) [See multi-brand routine · 96% fit](https://lovi.care/skincare/sg/skin/oily-skin)

### Neutrogena vs ISDIN routines for combination skin

#### ISDIN-focused routine

- Cleanser: [Fresh Soy Face Cleanser](https://lovi.care/skincare/sg/p/fresh/soy-face-cleanser/for/combination-skin) — Superior fit — [S$30.00 at Amazon](https://www.amazon.sg/dp/B0013522FC?tag=lovi-care-web-routine07-22&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- Hydrating Toner: [Whamisa Organic Flowers Toner Deep Rich](https://lovi.care/skincare/sg/p/whamisa/organic-flowers-toner-deep-rich/for/combination-skin) — Superior fit — [S$64.81 at Amazon](https://www.amazon.sg/dp/B01N7P9N8I?tag=lovi-care-web-routine07-22&linkCode=osi&th=1&psc=1) — Morning · Once a week
- SPF: [Eryfotona Actinica](https://lovi.care/skincare/sg/p/isdin/eryfotona-actinica/for/combination-skin) — High fit — [S$110.01 at Amazon](https://www.amazon.sg/dp/B07RXS4FQM?tag=lovi-care-web-routine07-22&linkCode=osi&th=1&psc=1) — Morning
- Pre-Cleanser: [Shu Uemura Ultime8 Sublime Beauty Cleansing Oil](https://lovi.care/skincare/sg/p/shu-uemura/ultime8-sublime-beauty-cleansing-oil/for/combination-skin) — Superior fit — [S$70.21 at Amazon](https://www.amazon.sg/dp/B0DNJKPSB8?tag=lovi-care-web-routine07-22&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Cleansing Toner: [Medicube Zero Pore Pad 2.0](https://lovi.care/skincare/sg/p/medicube/zero-pore-pad-2-0/for/combination-skin) — Superior fit — [S$36.48 at Amazon](https://www.amazon.sg/dp/B0CV7RX6ML?tag=lovi-care-web-routine07-22&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Serum or Treatment: [Flavo-C Serum](https://lovi.care/skincare/sg/p/isdin/flavo-c-serum/for/combination-skin) — High fit — [S$161.49 at Amazon](https://www.amazon.sg/dp/B01BMLQ086?tag=lovi-care-web-routine07-22&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Cleansing Mask: [HERBIVORE Botanicals Blue Tansy BHA and Enzyme Pore Refining Mask](https://lovi.care/skincare/sg/p/herbivore-botanicals/blue-tansy-bha-and-enzyme-pore-refining-mask/for/combination-skin) — Superior fit — [S$89.14 at Amazon](https://www.amazon.sg/dp/B015RRNQCY?tag=lovi-care-web-routine07-22&linkCode=osi&th=1&psc=1) — Once a week

#### Neutrogena-focused routine

- Cleanser: [Hydro Boost Water Gel](https://lovi.care/skincare/sg/p/neutrogena/hydro-boost-water-gel/for/combination-skin) — Low fit — [S$28.51 at Amazon](https://www.amazon.sg/dp/B0CX3CCJWV?tag=lovi-care-web-routine07-22&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- Hydrating Toner: [Alcohol-Free Toner](https://lovi.care/skincare/sg/p/neutrogena/alcohol-free-toner/for/combination-skin) — Average fit — [S$67.90 at Amazon](https://www.amazon.sg/dp/B01LTI056U?tag=lovi-care-web-routine07-22&linkCode=osi&th=1&psc=1) — Morning · Once a week
- Moisturizer: [Hydro Boost Hyaluronic Acid Serum](https://lovi.care/skincare/sg/p/neutrogena/hydro-boost-hyaluronic-acid-serum/for/combination-skin) — High fit — [S$31.79 at Amazon](https://www.amazon.sg/dp/B01HOHBS7K?tag=lovi-care-web-routine07-22&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- SPF: [Ultra Sheer Dry-Touch Sunscreen](https://lovi.care/skincare/sg/p/neutrogena/ultra-sheer-dry-touch-sunscreen/for/combination-skin) — Superior fit — [S$28.35 at Amazon](https://www.amazon.sg/dp/B004D2DR0Q?tag=lovi-care-web-routine07-22&linkCode=osi&th=1&psc=1) — Morning
- Pre-Cleanser: [Oil-Free Eye Makeup Remover](https://lovi.care/skincare/sg/p/neutrogena/oil-free-eye-makeup-remover/for/combination-skin) — High fit — [S$17.59 at Amazon](https://www.amazon.sg/dp/B07T9JV956?tag=lovi-care-web-routine07-22&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Cleansing Toner: [Medicube Zero Pore Pad 2.0](https://lovi.care/skincare/sg/p/medicube/zero-pore-pad-2-0/for/combination-skin) — Superior fit — [S$36.48 at Amazon](https://www.amazon.sg/dp/B0CV7RX6ML?tag=lovi-care-web-routine07-22&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Serum or Treatment: [Peach & Lily Glass Skin Refining Serum](https://lovi.care/skincare/sg/p/peach-and-lily/glass-skin-refining-serum/for/combination-skin) — Superior fit — [S$63.44 at Amazon](https://www.amazon.sg/dp/B08H4QPM19?tag=lovi-care-web-routine07-22&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Cleansing Mask: [HERBIVORE Botanicals Blue Tansy BHA and Enzyme Pore Refining Mask](https://lovi.care/skincare/sg/p/herbivore-botanicals/blue-tansy-bha-and-enzyme-pore-refining-mask/for/combination-skin) — Superior fit — [S$89.14 at Amazon](https://www.amazon.sg/dp/B015RRNQCY?tag=lovi-care-web-routine07-22&linkCode=osi&th=1&psc=1) — Once a week

[Buy ISDIN routine · S$562.14 · 92% fit](https://www.amazon.sg/gp/aws/cart/add.html?ASIN.1=B0013522FC&Quantity.1=1&ASIN.2=B01N7P9N8I&Quantity.2=1&ASIN.3=B07RXS4FQM&Quantity.3=1&ASIN.4=B0DNJKPSB8&Quantity.4=1&ASIN.5=B0CV7RX6ML&Quantity.5=1&ASIN.6=B01BMLQ086&Quantity.6=1&ASIN.7=B015RRNQCY&Quantity.7=1&AssociateTag=lovi-care-web-routine07-22) [Buy Neutrogena routine · S$363.20 · 82% fit](https://www.amazon.sg/gp/aws/cart/add.html?ASIN.1=B0CX3CCJWV&Quantity.1=1&ASIN.2=B01LTI056U&Quantity.2=1&ASIN.3=B01HOHBS7K&Quantity.3=1&ASIN.4=B004D2DR0Q&Quantity.4=1&ASIN.5=B07T9JV956&Quantity.5=1&ASIN.6=B0CV7RX6ML&Quantity.6=1&ASIN.7=B08H4QPM19&Quantity.7=1&ASIN.8=B015RRNQCY&Quantity.8=1&AssociateTag=lovi-care-web-routine07-22) [See multi-brand routine · 97% fit](https://lovi.care/skincare/sg/skin/combination-skin)

## Questions and answers

### Neutrogena or ISDIN: which is better?

Both Neutrogena and ISDIN offer great options, with Neutrogena outperforming on skin texture improvement and anti-aging while ISDIN delivers more ultralight sunscreens and lighter moisturizers. Lovi fit levels for the products on this page are High for Neutrogena and Superior for ISDIN across all skin types. [Retinol](https://lovi.care/skincare/sg/ingredients/retinol) helps stimulate [collagen](https://lovi.care/skincare/sg/ingredients/collagen) accumulation in naturally aged human skin.

[The Journal of Investigative Dermatology, 2000](https://pubmed.ncbi.nlm.nih.gov/10692106/) [Archives of Dermatology, 2007](https://pubmed.ncbi.nlm.nih.gov/17515510/)

### What is the difference between Neutrogena and ISDIN?

Neutrogena and ISDIN both offer gentle, hydrating skincare, but Neutrogena provides more options for anti-aging and skin texture improvement while ISDIN is often noted for its ultralight sunscreens.

### Neutrogena or ISDIN for dry skin?

Neutrogena has a High routine fit for dry skin with products like Hydro Boost [Hyaluronic Acid](https://lovi.care/skincare/sg/ingredients/hyaluronic-acid) [Serum](https://lovi.care/skincare/sg/ingredients/serum), which helps deliver deep hydration, while ISDIN offers a Superior routine fit for dry skin with ultralight sunscreens like Eryfotona Actinica.

[Journal of Pharmacy & Pharmaceutical Sciences, 2015](https://pubmed.ncbi.nlm.nih.gov/25877441/) [Dermatologic Therapy, 2022](https://pubmed.ncbi.nlm.nih.gov/36200921/)

### Neutrogena or ISDIN: which moisturizer is better?

Both Neutrogena and ISDIN offer effective moisturizers, with Neutrogena standing out for its anti-aging formulas and ISDIN excelling in lightweight textures and dry skin routines where Lovi fit is Superior. Neutrogena products on this page often feature retinol, which helps stimulate collagen accumulation in naturally aged skin. Additionally, hyaluronic acid helps improve skin quality and signs of aging.

[The Journal of Investigative Dermatology, 2000](https://pubmed.ncbi.nlm.nih.gov/10692106/) [Archives of Dermatology, 2007](https://pubmed.ncbi.nlm.nih.gov/17515510/)

### Which is more affordable, Neutrogena or ISDIN?

Neutrogena tends to be more affordable, while ISDIN is often noted for a high price point. Both brands offer products on this page with various fit levels for different skin types.

### Which brand was founded earlier, Neutrogena or ISDIN?

Neutrogena was founded earlier in 1930 in the United States, whereas ISDIN was founded later in 1975 in Spain.

### How many products with fragrance does Neutrogena have compared to ISDIN?

Neutrogena has 4 products with fragrance on this page, while ISDIN has 5 products with fragrance.

### Which brand performs better for skin texture improvement and anti-aging according to review themes?

Neutrogena performs better for skin texture improvement and anti-aging according to the review themes on this page. Its products on this page help improve skin texture and target signs of aging with ingredients like retinol, which stimulates collagen accumulation to help combat aging.

[The Journal of Investigative Dermatology, 2000](https://pubmed.ncbi.nlm.nih.gov/10692106/)

### Neutrogena or ISDIN for oily skin?

Both brands offer solid options for oily skin, but Lovi rates ISDIN Superior and Neutrogena High for this skin type. ISDIN features ultralight sunscreens and lightweight moisturizers that reviewers mostly mention, while the products on this page from Neutrogena include targeted oil-free options.

### Neutrogena or ISDIN: which sunscreen is better?

Both Neutrogena and ISDIN offer sunscreens that perform well, but ISDIN fits dry sensitive skin and mature skin at a Superior level on this page. Neutrogena sunscreens like Ultra Sheer Dry-Touch Sunscreen and Clear Face Liquid Lotion Sunscreen also provide Superior fit for sensitive and oily skin.

### Neutrogena or ISDIN for sensitive skin?

Both Neutrogena and ISDIN fit sensitive skin well, with Lovi rating the routine fit for sensitive skin as High for Neutrogena and Superior for ISDIN.

### Neutrogena or ISDIN for acne-prone skin?

Both Neutrogena and ISDIN achieve a High Lovi fit for acne-prone skin on the products on this page. Reviewers note that Neutrogena offers a broader selection of gentle, acne-safe options, while ISDIN delivers ultralight sunscreens.

## Research behind their key ingredients

- [Vitamin A antagonizes decreased cell growth and elevated collagen-degrading matrix metalloproteinases and stimulates collagen accumulation in naturally aged human skin](https://pubmed.ncbi.nlm.nih.gov/10692106/) Retinol · The Journal of Investigative Dermatology, 2000
- [Hyaluronic acid and wound healing](https://pubmed.ncbi.nlm.nih.gov/25877441/) Sodium hyaluronate · Journal of Pharmacy & Pharmaceutical Sciences, 2015
- [The effect of niacinamide on reducing cutaneous pigmentation and suppression of melanosome transfer](https://pubmed.ncbi.nlm.nih.gov/12100180/) Niacinamide · The British Journal of Dermatology, 2002
- [Skin delivery of epigallocatechin-3-gallate (EGCG) and hyaluronic acid loaded nano-transfersomes for antioxidant and anti-aging effects in UV radiation induced skin damage](https://pubmed.ncbi.nlm.nih.gov/28155509/) Antioxidants · Drug Delivery, 2017
- [Final report on the safety assessment of Benzyl Alcohol, Benzoic Acid, and Sodium Benzoate](https://pubmed.ncbi.nlm.nih.gov/11766131/) Benzyl alcohol · International Journal of Toxicology, 2001
- [Benefits of topical hyaluronic acid for skin quality and signs of skin aging: From literature review to clinical evidence](https://pubmed.ncbi.nlm.nih.gov/36200921/) Sodium hyaluronate, Hyaluronic acid · Dermatologic Therapy, 2022
- [Topical use of dexpanthenol in skin disorders](https://pubmed.ncbi.nlm.nih.gov/12113650/) Panthenol · American Journal of Clinical Dermatology, 2002
- [The Effect of Aloe Vera Clinical Trials on Prevention and Healing of Skin Wound: A Systematic Review](https://pubmed.ncbi.nlm.nih.gov/30666070/) Aloe barbadensis leaf extract · Iranian Journal of Medical Sciences, 2019
- [Improvement of naturally aged skin with vitamin A (retinol)](https://pubmed.ncbi.nlm.nih.gov/17515510/) Retinol · Archives of Dermatology, 2007
- [Final report on the safety assessment of BHT(1)](https://pubmed.ncbi.nlm.nih.gov/12396675/) Bht · International Journal of Toxicology, 2002
- [Anti-aging and brightening effects of a topical treatment containing vitamin C, vitamin E, and raspberry leaf cell culture extract: A split-face, randomized controlled trial](https://pubmed.ncbi.nlm.nih.gov/31975502/) Ascorbic acid, Tocopherol · Journal of Cosmetic Dermatology, 2020
- [Molecular basis of retinol anti-ageing properties in naturally aged human skin in vivo](https://pubmed.ncbi.nlm.nih.gov/27261203/) Retinol · International Journal of Cosmetic Science, 2017
- [Prospective, randomized, double-blind assessment of topical bakuchiol and retinol for facial photoageing](https://pubmed.ncbi.nlm.nih.gov/29947134/) Bakuchiol · The British Journal of Dermatology, 2019
- [Effects of ascorbic acid on gingival melanin pigmentation in vitro and in vivo](https://pubmed.ncbi.nlm.nih.gov/19186973/) Ascorbyl glucoside · Journal of Periodontology, 2009
- [Apigenin inhibits UVA-induced cytotoxicity in vitro and prevents signs of skin aging in vivo](https://pubmed.ncbi.nlm.nih.gov/27279007/) Chamomilla recutita flower extract matricaria flower extract · International Journal of Molecular Medicine, 2016
- [Skin penetration and stabilization of formulations containing microfine titanium dioxide as physical UV filter](https://pubmed.ncbi.nlm.nih.gov/18503414/) Titanium dioxide · International Journal of Cosmetic Science, 2000
- [Treatment of acne with a combination of propolis, tea tree oil, and Aloe vera compared to erythromycin cream: two double-blind investigations](https://pubmed.ncbi.nlm.nih.gov/30588129/) Aloe barbadensis leaf juice, Aloe barbadensis leaf extract · Clinical Pharmacology, 2018
- [Topical benzoyl peroxide for acne](https://pubmed.ncbi.nlm.nih.gov/32175593/) Benzoyl peroxide · The Cochrane Database of Systematic Reviews, 2020
- [Antiaging efficacy of melatonin-based day and night creams: a randomized, split-face, assessor-blinded proof-of-concept trial](https://pubmed.ncbi.nlm.nih.gov/29416368/) Melatonin · Clinical, Cosmetic and Investigational Dermatology, 2018
- [Sacha Inchi Oil (Plukenetia volubilis L.), effect on adherence of Staphylococus aureus to human skin explant and keratinocytes in vitro](https://pubmed.ncbi.nlm.nih.gov/26087228/) Plukenetia volubilis seed oil · Journal of Ethnopharmacology, 2015
- [Effect of a topical antioxidant serum containing vitamin C, vitamin E, and ferulic acid after Q-switched 1064-nm Nd:YAG laser for treatment of environment-induced skin pigmentation](https://pubmed.ncbi.nlm.nih.gov/32052907/) Ascorbic acid · Journal of Cosmetic Dermatology, 2020
- [The 24-hour skin hydration and barrier function effects of a hyaluronic 1%, glycerin 5%, and Centella asiatica stem cells extract moisturizing fluid: an intra-subject, randomized, assessor-blinded study](https://pubmed.ncbi.nlm.nih.gov/28860834/) Glycerin · Clinical, Cosmetic and Investigational Dermatology, 2017
- [The human stratum corneum layer: an effective barrier against dermal uptake of different forms of topically applied micronised titanium dioxide](https://pubmed.ncbi.nlm.nih.gov/11509913/) Titanium dioxide · Skin Pharmacology and Applied Skin Physiology, 2001
- [Benzoyl peroxide treatment decreases Cutibacterium acnes in shoulder surgery, from skin incision until wound closure](https://pubmed.ncbi.nlm.nih.gov/33545336/) Benzoyl peroxide · Journal of Shoulder and Elbow Surgery, 2021
- [Randomized controlled study for the anti-aging effect of human adipocyte-derived mesenchymal stem cell media combined with niacinamide after laser therapy](https://pubmed.ncbi.nlm.nih.gov/33103316/) Niacinamide · Journal of Cosmetic Dermatology, 2021
- [Efficacy and Safety of a Fixed-Dose Clindamycin Phosphate 1.2%, Benzoyl Peroxide 3.1%, and Adapalene 0.15% Gel for Moderate-to-Severe Acne: A Randomized Phase II Study of the First Triple-Combination Drug](https://pubmed.ncbi.nlm.nih.gov/34674160/) Benzoyl peroxide · American Journal of Clinical Dermatology, 2022
- [Reduction in the appearance of facial hyperpigmentation by topical N-acetyl glucosamine](https://pubmed.ncbi.nlm.nih.gov/17348991/) Acetyl glucosamine, Neoglucosamine · Journal of Cosmetic Dermatology, 2007
- [Reduction in the appearance of facial hyperpigmentation after use of moisturizers with a combination of topical niacinamide and N-acetyl glucosamine: results of a randomized, double-blind, vehicle-controlled trial](https://pubmed.ncbi.nlm.nih.gov/19845667/) Acetyl glucosamine, Neoglucosamine · The British Journal of Dermatology, 2010
- [Quaternized carboxymethyl chitosan/organic montmorillonite nanocomposite as a novel cosmetic ingredient against skin aging](https://pubmed.ncbi.nlm.nih.gov/28732847/) Bentonite · Carbohydrate Polymers, 2017
- [A new topical panthenol-containing emollient: Results from two randomized controlled studies assessing its skin moisturization and barrier restoration potential, and the effect on skin microflora](https://pubmed.ncbi.nlm.nih.gov/27425824/) Panthenol · The Journal of Dermatological Treatment, 2017
- [Phytosphingosine enhances moisture level in human skin barrier through stimulation of the filaggrin biosynthesis and degradation leading to NMF formation](https://pubmed.ncbi.nlm.nih.gov/28936777/) Hydration complex · Archives of Dermatological Research, 2017
- [A Double-Blinded, Randomized, Vehicle-Controlled Study of the Efficacy of Moisturizer Containing Licochalcone A, Decanediol, L-Carnitine, and Salicylic Acid for Prevention of Acne Relapse in Asian Population](https://pubmed.ncbi.nlm.nih.gov/33150170/) Salicylic acid · BioMed Research International, 2020
- [Senomorphic activity of a combination of niacinamide and hyaluronic acid: correlation with clinical improvement of skin aging](https://pubmed.ncbi.nlm.nih.gov/39009698/) Niacinamide · Scientific Reports, 2024
- [Stable Ozonides with Vitamin E Acetate versus Corticosteroid in the Treatment of Lichen Sclerosus in Foreskin: Evaluation of Effects on Inflammation](https://pubmed.ncbi.nlm.nih.gov/30991399/) Tocopheryl acetate · Urologia Internationalis, 2019
- [Efficacy of a topical gel containing chitosan, chlorhexidine, allantoin and dexpanthenol for pain and inflammation control after third molar surgery: A randomized and placebo-controlled clinical trial](https://pubmed.ncbi.nlm.nih.gov/32683390/) Allantoin · Medicina Oral, Patologia Oral Y Cirugia Bucal, 2020
- [High molecular compounds (polysaccharides and proanthocyanidins) from Hamamelis virginiana bark: influence on human skin keratinocyte proliferation and differentiation and influence on irritated skin](https://pubmed.ncbi.nlm.nih.gov/11684194/) Witch hazel extract · Phytochemistry, 2001
- [The efficacy of glycolic acid, salicylic acid, gluconolactone, and licochalcone A combined with 0.1% adapalene vs adapalene monotherapy in mild-to-moderate acne vulgaris: a double-blinded within-person comparative study](https://pubmed.ncbi.nlm.nih.gov/30858720/) Glycolic acid · Clinical, Cosmetic and Investigational Dermatology, 2019
- [A comparative study of gluconolactone versus benzoyl peroxide in the treatment of acne](https://pubmed.ncbi.nlm.nih.gov/1303072/) Gluconolactone · The Australasian Journal of Dermatology, 1992
- [Anti-inflammatory activity of parthenolide-depleted Feverfew (Tanacetum parthenium)](https://pubmed.ncbi.nlm.nih.gov/19112586/) Chrysanthemum parthenium flower leaf stem juice · Inflammopharmacology, 2009
- [Efficacy of a multitargeted, salicylic acid-based dermocosmetic cream compared to benzoyl peroxide 5% in Acne vulgaris: Results from a randomized study](https://pubmed.ncbi.nlm.nih.gov/37941097/) Salicylic acid · Journal of Cosmetic Dermatology, 2024
- [Biomimetic hyaluronic acid-stabilized zinc oxide nanoparticles in acne treatment: A preclinical and clinical approach](https://pubmed.ncbi.nlm.nih.gov/40254135/) Zinc oxide · Journal of Controlled Release, 2025
- [Efficacy and Tolerability of a Skin Brightening/Anti-Aging Cosmeceutical Containing Retinol 0.5%, Niacinamide, Hexylresorcinol, and Resveratrol](https://pubmed.ncbi.nlm.nih.gov/27391637/) Hexylresorcinol · Journal of Drugs in Dermatology, 2016
- [Comparison of clinical efficacies of sodium ascorbyl phosphate, retinol and their combination in acne treatment](https://pubmed.ncbi.nlm.nih.gov/19134126/) Sodium ascorbyl phosphate · International Journal of Cosmetic Science, 2009
- [Evaluation of dermal extracellular matrix and epidermal-dermal junction modifications using matrix-assisted laser desorption/ionization mass spectrometric imaging, in vivo reflectance confocal microscopy, echography, and histology: effect of age and peptide applications](https://pubmed.ncbi.nlm.nih.gov/25817264/) Palmitoyl tripeptide-1, Palmitoyl tetrapeptide-7 · Journal of Cosmetic Dermatology, 2015
- [Preparation and evaluation of benzalkonium chloride hand sanitizer as a potential alternative for alcohol-based hand gels](https://pubmed.ncbi.nlm.nih.gov/34408542/) Benzalkonium chloride · Saudi Pharmaceutical Journal, 2021
- [Retaining Skin Barrier Function Properties of the Stratum Corneum with Components of the Natural Moisturizing Factor-A Randomized, Placebo-Controlled Double-Blind In Vivo Study](https://pubmed.ncbi.nlm.nih.gov/33809557/) Hydration complex · Molecules, 2021
- [Superior even skin tone and anti-ageing benefit of a combination of 4-hexylresorcinol and niacinamide](https://pubmed.ncbi.nlm.nih.gov/34958693/) Hexylresorcinol · International Journal of Cosmetic Science, 2022
- [Efficacy and safety of microencapsulated benzoyl peroxide and microencapsulated tretinoin for the treatment of acne vulgaris: Results from two phase 3 double-blind, randomized, vehicle-controlled studies](https://pubmed.ncbi.nlm.nih.gov/37356627/) Benzoyl peroxide · Journal of the American Academy of Dermatology, 2023
- [A Salicylic Acid-Based Dermocosmetic is Effective as an Adjunct to Benzoyl Peroxide for Mild to Moderate Acne and as Monotherapy in Maintenance Post Benzoyl Peroxide](https://pubmed.ncbi.nlm.nih.gov/38051857/) Salicylic acid · Journal of Drugs in Dermatology, 2023
- [Efficacy and tolerability of the investigational topical cream SD-101 (6% allantoin) in patients with epidermolysis bullosa: a phase 3, randomized, double-blind, vehicle-controlled trial (ESSENCE study)](https://pubmed.ncbi.nlm.nih.gov/32576219/) Allantoin · Orphanet Journal of Rare Diseases, 2020
- [Botulinum toxin injection as a single or combined treatment with non-cross-linked high molecular weight and low molecular weight hyaluronic acid gel for neck rejuvenation: A randomized clinical trial](https://pubmed.ncbi.nlm.nih.gov/35775872/) Hydrolyzed hyaluronic acid · Dermatologic Therapy, 2022
- [Subclinical, non-erythematous irritation with an open assay model (washing): sodium lauryl sulfate (SLS) versus sodium laureth sulfate (SLES)](https://pubmed.ncbi.nlm.nih.gov/11278060/) Sodium laureth sulfate · Food and Chemical Toxicology, 2001
- [Challenging the safety and efficacy of topically applied chlorogenic acid, apigenin, kaempferol, and naringenin by HET-CAM, HPLC-TBARS-EVSC, and laser Doppler flowmetry](https://pubmed.ncbi.nlm.nih.gov/38831914/) Grapefruit extract · Frontiers in Chemistry, 2024
- [Safety assessment of cyclomethicone, cyclotetrasiloxane, cyclopentasiloxane, cyclohexasiloxane, and cycloheptasiloxane](https://pubmed.ncbi.nlm.nih.gov/22247236/) Cyclopentasiloxane · International Journal of Toxicology, 2011
- [Is benzyl alcohol a significant contact sensitizer?](https://pubmed.ncbi.nlm.nih.gov/35080274/) Benzyl alcohol · Journal of the European Academy of Dermatology and Venereology, 2022
- [Evaluation of moisturizing and irritation potential of sacha inchi oil](https://pubmed.ncbi.nlm.nih.gov/31441999/) Plukenetia volubilis seed oil · Journal of Cosmetic Dermatology, 2020
- [Whitening effect of alpha-bisabolol in Asian women subjects](https://pubmed.ncbi.nlm.nih.gov/20642768/) Bisabolol · International Journal of Cosmetic Science, 2010
- [Clinical evaluation of the efficacy of a facial serum containing dioic acid, glycolic acid, salicylic acid, LHA, citric acid, and HEPES in treating post-inflammatory hyperchromia and controlling oily skin in patients with acne vulgaris](https://pubmed.ncbi.nlm.nih.gov/33617668/) Citric acid · Journal of Cosmetic Dermatology, 2021
- [Parthenolide-depleted Feverfew (Tanacetum parthenium) protects skin from UV irradiation and external aggression](https://pubmed.ncbi.nlm.nih.gov/18071724/) Chrysanthemum parthenium flower leaf stem juice · Archives of Dermatological Research, 2008
- [Assessment of Combined Ascorbyl Palmitate (AP) and Sodium Ascorbyl Phosphate (SAP) on Facial Skin Sebum Control in Female Healthy Volunteers](https://pubmed.ncbi.nlm.nih.gov/27756097/) Sodium ascorbyl phosphate · Drug Research, 2017
- [Solid lipid nanoparticles bearing oxybenzone: in-vitro and in-vivo evaluation](https://pubmed.ncbi.nlm.nih.gov/19622017/) Oxybenzone, Oxybenzone-free formula · Journal of Microencapsulation, 2010
- [Nanostructured Lipid Carrier for Topical Application of N-Acetyl Glucosamine](https://pubmed.ncbi.nlm.nih.gov/28101465/) Acetyl glucosamine, Neoglucosamine · Advanced Pharmaceutical Bulletin, 2016
- [Axillary hyperhidrosis. Local treatment with aluminium-chloride hexahydrate 25% in absolute ethanol with and without supplementary treatment with triethanolamine](https://pubmed.ncbi.nlm.nih.gov/2449022/) Triethanolamine · Acta Dermato-venereologica, 1988
- [Using ordered mesoporous silica SBA-15 to limit cutaneous penetration and transdermal permeation of organic UV filters](https://pubmed.ncbi.nlm.nih.gov/31437563/) Butyl methoxydibenzoylmethane · International Journal of Pharmaceutics, 2019
- [Comparison of methods for assessing photoprotection against ultraviolet A in vivo](https://pubmed.ncbi.nlm.nih.gov/3819071/) Butyl methoxydibenzoylmethane · Journal of the American Academy of Dermatology, 1987
- [Enhancing Photoprotection and Mitigating Ex Vivo Stratum Corneum Oxidative Stress: A Multifunctional Strategy Combining Rosmarinic Acid with UVB Filters](https://pubmed.ncbi.nlm.nih.gov/40227214/) Octocrylene · Antioxidants, 2025
- [Rates of allergic sensitization and irritation to oxybenzone-containing sunscreen products: a quantitative meta-analysis of 64 exaggerated use studies](https://pubmed.ncbi.nlm.nih.gov/18717962/) Helioplex technology, Helioplex · Photodermatology, Photoimmunology & Photomedicine, 2008
- [Influence of vitamin E acetate on stratum corneum hydration](https://pubmed.ncbi.nlm.nih.gov/9706379/) Tocopheryl acetate · Arzneimittel-Forschung, 1998
- [Topical Zinc Oxide Nanoparticle Formulations for Acne Vulgaris: A Systematic Review of Pre-Clinical and Early-Phase Clinical Evidence](https://pubmed.ncbi.nlm.nih.gov/41007718/) Zinc oxide · Biomedicines, 2025
- [A controlled, three-part trial to investigate the barrier function and skin hydration properties of six skin protectants](https://pubmed.ncbi.nlm.nih.gov/16439809/) Dimethicone · Ostomy/wound Management, 2005
- [Comparative physicochemical stability and clinical anti-wrinkle efficacy of transdermal emulgel preparations of 5% sodium ascorbyl phosphate and or ascorbic acid on human volunteers](https://pubmed.ncbi.nlm.nih.gov/32383548/) Sodium ascorbyl phosphate · Journal of Cosmetic Dermatology, 2021
- [TiO2-embedded mesoporous silica with lower porosity is beneficial to adsorb the pollutants and retard UV filter absorption: A possible application for outdoor skin protection](https://pubmed.ncbi.nlm.nih.gov/36455708/) Butyl methoxydibenzoylmethane · European Journal of Pharmaceutical Sciences, 2023
- [A new formula for a mild body cleanser: sodium laureth sulphate supplemented with sodium laureth carboxylate and lauryl glucoside](https://pubmed.ncbi.nlm.nih.gov/24617572/) Lauryl glucoside · International Journal of Cosmetic Science, 2014
- [Evaluation of the Efficacy and Safety of a Panthenol-Enriched Mask for Skin Barrier Recovery After Facial Laser Treatment: Results of a Double-Blind Randomized Controlled Study](https://pubmed.ncbi.nlm.nih.gov/40613435/) Panthenol · Journal of Cosmetic Dermatology, 2025
- [Safety of a preservative system containing 1,2-hexanediol and caprylyl glycol](https://pubmed.ncbi.nlm.nih.gov/19514921/) Caprylyl glycol · Cutaneous and Ocular Toxicology, 2009
- [Cucumber (Cucumis sativus L.) with heterologous poly-γ-glutamic acid has skin moisturizing, whitening and anti-wrinkle effects](https://pubmed.ncbi.nlm.nih.gov/38336313/) Cucumis sativus fruit extract · International Journal of Biological Macromolecules, 2024
- [Efficacy and Tolerability of Stable Hybrid Cooperative Complexes of High- and Low-Molecular Weight Hyaluronic Acid in Asian Patients: An Open-Label Study](https://pubmed.ncbi.nlm.nih.gov/40921777/) Hydrolyzed hyaluronic acid · Aesthetic Plastic Surgery, 2026
- [Prospective, randomized, double-blind clinical study of split-body comparison of topical hydroquinone and hexylresorcinol for skin pigment appearance](https://pubmed.ncbi.nlm.nih.gov/36502500/) Hexylresorcinol · Archives of Dermatological Research, 2023
- [Instrumental, clinical and subjective evaluation of the efficacy of a cosmetic treatment for home use](https://pubmed.ncbi.nlm.nih.gov/30040516/) Acetyl glucosamine, Neoglucosamine · Journal of Cosmetic and Laser Therapy, 2019
- [Ginkgo biloba leaves extract's cosmeceutical evaluation: a preliminary assessments on human volunteers towards achieving improved skin condition and rejuvenation](https://pubmed.ncbi.nlm.nih.gov/37074796/) Ginkgo biloba leaf extract · Drug Development and Industrial Pharmacy, 2023
- [Nanocomplex of quaternized cyclodextrin grafted chitosan and hyaluronic acid for a skin delivery](https://pubmed.ncbi.nlm.nih.gov/36279763/) Hydrolyzed hyaluronic acid · Colloids and Surfaces. B, Biointerfaces, 2022
- [Functional properties and skin care effects of sodium trehalose sulfate](https://pubmed.ncbi.nlm.nih.gov/38606717/) Trehalose · Skin Research and Technology, 2024
- [A Double-Blind, 12-Week Study to Evaluate the Antiaging Efficacy of a Cream Containing the NFκB Inhibitor 4-Hexyl-1, 3-Phenylenediol and Ascorbic Acid-2 Glucoside in Adult Females](https://pubmed.ncbi.nlm.nih.gov/27272084/) Ascorbyl glucoside · Journal of Drugs in Dermatology, 2016
- [Nanostructured Lipid Carrier Based Gel Containing α-Tocopherol and α-Tocopheryl Acetate for Synergistic Cutaneous Antiaging Efficacy](https://pubmed.ncbi.nlm.nih.gov/41309687/) Tocopheryl acetate · Scientific Reports, 2025
- [Evaulation of irritation potential of surfactant mixtures](https://pubmed.ncbi.nlm.nih.gov/18503452/) Sodium laureth sulfate · International Journal of Cosmetic Science, 1999
- [Comparison of clindamycin 1% and benzoyl peroxide 5% gel to a novel composition containing salicylic acid, capryloyl salicylic acid, HEPES, glycolic acid, citric acid, and dioic acid in the treatment of acne vulgaris](https://pubmed.ncbi.nlm.nih.gov/23545907/) Citric acid · Journal of Drugs in Dermatology, 2013
- [Effect of an Emollient Emulsion Containing 15.0% of Caprylic/Capric Triglyceride on the Urocanic Acid of the Stratum Corneum](https://pubmed.ncbi.nlm.nih.gov/37109405/) Caprylic capric triglyceride · Life, 2023
- [Facial disbiosis and UV filters](https://pubmed.ncbi.nlm.nih.gov/39499337/) Ethylhexyl salicylate · Archives of Dermatological Research, 2024
- [A Randomized Controlled Trial of the Genistein Plus Bakuchiol and Vitamins (GEN+) Product for Male Facial Skin: Effects on Skin Appearance and Properties](https://pubmed.ncbi.nlm.nih.gov/41562471/) Bakuchiol · Skin Research and Technology, 2026
- [Treatment with Ascorbyl Glucoside-Arginine Complex Ameliorates Solar Lentigos](https://pubmed.ncbi.nlm.nih.gov/39769217/) Ascorbyl glucoside · International Journal of Molecular Sciences, 2024
- [Safety assessment on comedogenicity of dermatological products containing d-alpha tocopheryl acetate in Asian subjects: A double-blind randomized controlled trial](https://pubmed.ncbi.nlm.nih.gov/34471722/) Tocopheryl acetate · Contemporary Clinical Trials Communications, 2021
- [Portulaca oleracea extract relieves skin barrier damage induced by increased photosensitivity after GA peeling](https://pubmed.ncbi.nlm.nih.gov/35920724/) Portulaca oleracea extract · Cutaneous and Ocular Toxicology, 2022
- [The clinical efficacy of a new emulsion for acne and conspicuous facial pore amelioration](https://pubmed.ncbi.nlm.nih.gov/38140770/) Lens esculenta seed extract · Journal of Cosmetic Dermatology, 2024
- [Retrospective Review of Dermal Safety Studies of Organic Sunscreens](https://pubmed.ncbi.nlm.nih.gov/40911743/) Ethylhexyl salicylate · Journal of Drugs in Dermatology, 2025
- [Acetyl Dipeptide-31 Amide: A Novel Cosmetic Anti-Inflammatory Peptide That Demonstrates Anti-Aging, Firming, and Lifting Benefits](https://pubmed.ncbi.nlm.nih.gov/39761149/) Acetyl dipeptide-31 amide · Journal of Drugs in Dermatology, 2025
- [Natural Moisturizing Factor-Enriched Formulations Compared to a Ceramide-Based Cream](https://pubmed.ncbi.nlm.nih.gov/38443132/) Hydration complex · Journal of Drugs in Dermatology, 2024
- [Synergistic combination: Developing a natural carrier-free assembled gel through hydrogen bond reconstruction strategy for efficient skin photo-damage restoration](https://pubmed.ncbi.nlm.nih.gov/41129958/) Sodium pca · Biomaterials Advances, 2026
- [Clinical Efficacy of Topical Ascorbic Acid 2-Glucoside in Enhancing Outcomes of Laser Gingival Depigmentation: A Randomized Controlled Trial](https://pubmed.ncbi.nlm.nih.gov/42147661/) Ascorbyl glucoside · Cureus, 2026
- [Efficacy and safety of combination cream of stimu-tex AS™ (spent grain wax, Argania Spinosa Kernel oil, Butyrospermum Parkii (shea butter) extract), and saccharide isomerate after fractional CO2 laser procedure: split-face, double blinded, randomized controlled trial](https://pubmed.ncbi.nlm.nih.gov/41134387/) Butyrospermum parkii butter shea butter · Lasers in Medical Science, 2025
- [The Therapeutic Effects of a Bentonite-Based Facial Mask With Alcea sulphurea Extract on Acne Severity and Patient Experience: Add-On Randomized Controlled Clinical Trial](https://pubmed.ncbi.nlm.nih.gov/41347526/) Bentonite · Journal of Cosmetic Dermatology, 2025
- [Impact of dermal emulsions containing diacyl phospholipids, mono acyl phospholipids, sodium lauryl ether sulfate and polysorbate 80 in combination with UVA irradiation on human skin physiology in vivo: A pilot study](https://pubmed.ncbi.nlm.nih.gov/42617898/) Sodium laureth sulfate · International Journal of Pharmaceutics, 2026
- [Split-face evaluation: Gluconolactone plus oxybrasion versus gluconolactone plus microneedling. The effects on skin parameters](https://pubmed.ncbi.nlm.nih.gov/37357656/) Gluconolactone · Skin Research and Technology, 2023
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## The brands

- American skincare: [Neutrogena](https://lovi.care/skincare/sg/brands/neutrogena)
- Spanish skincare: [ISDIN](https://lovi.care/skincare/sg/brands/isdin)

## More comparisons

- [SKIN1004 vs Neutrogena](https://lovi.care/skincare/sg/compare/skin1004-vs-neutrogena)
- [SKIN1004 vs ISDIN](https://lovi.care/skincare/sg/compare/skin1004-vs-isdin)
- [Anua vs Neutrogena](https://lovi.care/skincare/sg/compare/anua-vs-neutrogena)
- [Anua vs ISDIN](https://lovi.care/skincare/sg/compare/anua-vs-isdin)
- [Medicube vs Neutrogena](https://lovi.care/skincare/sg/compare/medicube-vs-neutrogena)
- [Medicube vs ISDIN](https://lovi.care/skincare/sg/compare/medicube-vs-isdin)
- [The Ordinary vs Neutrogena](https://lovi.care/skincare/sg/compare/the-ordinary-vs-neutrogena)
- [The Ordinary vs ISDIN](https://lovi.care/skincare/sg/compare/the-ordinary-vs-isdin)
- [Beauty of Joseon vs Neutrogena](https://lovi.care/skincare/sg/compare/beauty-of-joseon-vs-neutrogena)
- [Beauty of Joseon vs ISDIN](https://lovi.care/skincare/sg/compare/beauty-of-joseon-vs-isdin)
- [COSRX vs Neutrogena](https://lovi.care/skincare/sg/compare/cosrx-vs-neutrogena)
- [COSRX vs ISDIN](https://lovi.care/skincare/sg/compare/cosrx-vs-isdin)
- [CeraVe vs Neutrogena](https://lovi.care/skincare/sg/compare/cerave-vs-neutrogena)
- [CeraVe vs ISDIN](https://lovi.care/skincare/sg/compare/cerave-vs-isdin)
- [La Roche-Posay vs Neutrogena](https://lovi.care/skincare/sg/compare/la-roche-posay-vs-neutrogena)
- [La Roche-Posay vs ISDIN](https://lovi.care/skincare/sg/compare/la-roche-posay-vs-isdin)
- [Dr. Althea vs Neutrogena](https://lovi.care/skincare/sg/compare/dr-althea-vs-neutrogena)
- [Dr. Althea vs ISDIN](https://lovi.care/skincare/sg/compare/dr-althea-vs-isdin)
- [Some By Mi vs Neutrogena](https://lovi.care/skincare/sg/compare/some-by-mi-vs-neutrogena)
- [Some By Mi vs ISDIN](https://lovi.care/skincare/sg/compare/some-by-mi-vs-isdin)

## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this comparison: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/compare/neutrogena-vs-isdin
- United Kingdom: https://lovi.care/skincare/uk/compare/neutrogena-vs-isdin
- Ireland: https://lovi.care/skincare/ie/compare/neutrogena-vs-isdin
- Germany: https://lovi.care/skincare/de/compare/neutrogena-vs-isdin
- France: https://lovi.care/skincare/fr/compare/neutrogena-vs-isdin
- Italy: https://lovi.care/skincare/it/compare/neutrogena-vs-isdin
- Netherlands: https://lovi.care/skincare/nl/compare/neutrogena-vs-isdin
- Spain: https://lovi.care/skincare/es/compare/neutrogena-vs-isdin
- Canada: https://lovi.care/skincare/ca/compare/neutrogena-vs-isdin
- Australia: https://lovi.care/skincare/au/compare/neutrogena-vs-isdin
- Singapore: https://lovi.care/skincare/sg/compare/neutrogena-vs-isdin (this page)
- Saudi Arabia: https://lovi.care/skincare/sa/compare/neutrogena-vs-isdin
- United Arab Emirates: https://lovi.care/skincare/ae/compare/neutrogena-vs-isdin