# Neutrogena vs FRE

Page: https://lovi.care/skincare/sg/compare/neutrogena-vs-fre

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Singapore.

Neutrogena and FRE are trusted skincare brands recognized for distinct offerings and formulations. The former provides moisturizers, sunscreens, cleansers, and toners with [glycerin](https://lovi.care/skincare/sg/ingredients/glycerin), [hyaluronic acid](https://lovi.care/skincare/sg/ingredients/hyaluronic-acid), and [dimethicone](https://lovi.care/skincare/sg/ingredients/dimethicone), while the latter is known for targeted [Argan Oil](https://lovi.care/skincare/sg/ingredients/argan-oil). Both brands suit sensitive, mature, and acne-prone skin best through gentle and nourishing compositions. They differ as the first relies on scientific backing for barrier function, wrinkle reduction, and moisture retention, whereas the second focuses on balancing and supporting the complexion.

Neutrogena is an American skincare brand founded in 1930 and owned by Kimberly-Clark Corporation since 2026.

[investor.kimberly-clark.com](https://www.investor.kimberly-clark.com/news-releases/news-release-details/kimberly-clark-completes-acquisition-kenvue-creating-preeminent) [en.wikipedia.org](https://en.wikipedia.org/wiki/Neutrogena) [investors.kenvue.com](https://investors.kenvue.com/financial-news/news-details/2025/Kimberly-Clark-to-Acquire-Kenvue-Creating-a-32-Billion-Global-Health-and-Wellness-Leader/default.aspx)

This page compares some of the most popular Neutrogena and FRE products; for every product of both brands, with a fit score for your own skin, [use the Lovi app](https://app.pora.ai/vqqJ/j1xj2b6o?af_sub2=compare&af_sub3=selection_note&af_sub4=pgbe31a12a6e).

### Popular Neutrogena vs FRE products

#### Neutrogena

- [Hydro Boost Water Gel](https://lovi.care/skincare/sg/p/neutrogena/hydro-boost-water-gel/for/sensitive-skin) — Average fit — [S$28.51 at Amazon](https://www.amazon.sg/dp/B0CX3CCJWV?tag=lovi-care-web-product0e-22&linkCode=osi&th=1&psc=1)
- [Ultra Sheer Dry-Touch Sunscreen](https://lovi.care/skincare/sg/p/neutrogena/ultra-sheer-dry-touch-sunscreen/for/combination-skin) — Superior fit — [S$28.35 at Amazon](https://www.amazon.sg/dp/B004D2DR0Q?tag=lovi-care-web-product0e-22&linkCode=osi&th=1&psc=1)
- [HYDRO BOOST WATER CREAM](https://lovi.care/skincare/sg/p/neutrogena/hydro-boost-water-cream/for/dry-skin) — Superior fit — [S$28.51 at Amazon](https://www.amazon.sg/dp/B0CX3CCJWV?tag=lovi-care-web-product0e-22&linkCode=osi&th=1&psc=1)
- [Ultra Gentle Daily Cleanser](https://lovi.care/skincare/sg/p/neutrogena/ultra-gentle-daily-cleanser/for/mature-skin) — Superior fit — [S$82.61 at Amazon](https://www.amazon.sg/dp/B08CSLHGL2?tag=lovi-care-web-product0e-22&linkCode=osi&th=1&psc=1)
- [Rapid Wrinkle Repair Regenerating Cream](https://lovi.care/skincare/sg/p/neutrogena/rapid-wrinkle-repair-regenerating-cream/for/mature-skin) — High fit — [S$36.58 at Amazon](https://www.amazon.sg/dp/B0725JP4TN?tag=lovi-care-web-product0e-22&linkCode=osi&th=1&psc=1)
- [Oil-Free Eye Makeup Remover](https://lovi.care/skincare/sg/p/neutrogena/oil-free-eye-makeup-remover/for/dark-spots) — Superior fit — [S$17.59 at Amazon](https://www.amazon.sg/dp/B07T9JV956?tag=lovi-care-web-product0e-22&linkCode=osi&th=1&psc=1)
- [Retinol Regenerating Cream](https://lovi.care/skincare/sg/p/neutrogena/retinol-regenerating-cream/for/mature-skin) — Average fit
- [COLLAGEN BANK Moisturizer](https://lovi.care/skincare/sg/p/neutrogena/collagen-bank-moisturizer/for/dry-skin) — Average fit — [S$28.16 at Amazon](https://www.amazon.sg/dp/B0D43JLX7H?tag=lovi-care-web-product0e-22&linkCode=osi&th=1&psc=1)

#### FRE

- [Argan Oil](https://lovi.care/skincare/sg/p/fre/argan-oil/for/dry-sensitive-skin) — High fit

## Questions and answers

### Neutrogena or FRE: which is better?

Neutrogena is the better choice for most shoppers on this page because it offers a wide range of products with High and Superior Lovi fit levels for various skin types, whereas FRE only features a single [argan oil](https://lovi.care/skincare/sg/ingredients/argan-oil) product with at best High fit for dry sensitive skin. Reviewers mostly mention that Neutrogena provides deeply hydrating and lightweight moisturizers.

### What is the difference between Neutrogena and FRE?

Neutrogena is a much larger and older brand founded in the United States in 1930, offering a wide range of products on this page that fit sensitive, mature, and dry skin best. In contrast, FRE was founded in 2016 as an independent brand and features only a single product on this page, which has a High fit level for dry sensitive skin.

### Which is more affordable, Neutrogena or FRE?

The provided page facts do not contain pricing information for either Neutrogena or FRE, so it is not possible to determine which brand is more affordable.

### Which causes fewer breakouts, Neutrogena or FRE?

Neutrogena has a wide range of products with high or superior Lovi fit levels for acne-prone skin, whereas FRE features only Argan Oil on this page, which has an average fit level for acne-prone skin. Neutrogena offers many acne-safe and gentle moisturizers and cleansers, while its formulations help address breakouts through key ingredients like [salicylic acid](https://lovi.care/skincare/sg/ingredients/salicylic-acid).

### How does the founding year and company ownership compare between Neutrogena and FRE?

Neutrogena was founded in 1930 in the United States and has been owned by the Kimberly-Clark Corporation since 2026. In comparison, FRE was founded in 2016 and is independently owned.

### Which brand offers more fragrance-free product options?

Neutrogena offers more fragrance-free product options, with 35 out of 39 products on this page listing no fragrance.

### How do the Lovi fit levels for dry skin compare between Neutrogena's moisturizers and FRE's Argan Oil?

Neutrogena offers several moisturizers with a Superior or High Lovi fit for dry skin, whereas FRE's Argan Oil has an Average Lovi fit for dry skin. Reviewers often mention that Neutrogena provides deeply hydrating moisturizers.

## Research behind their key ingredients

- [Vitamin A antagonizes decreased cell growth and elevated collagen-degrading matrix metalloproteinases and stimulates collagen accumulation in naturally aged human skin](https://pubmed.ncbi.nlm.nih.gov/10692106/) Retinol · The Journal of Investigative Dermatology, 2000
- [Hyaluronic acid and wound healing](https://pubmed.ncbi.nlm.nih.gov/25877441/) Sodium hyaluronate · Journal of Pharmacy & Pharmaceutical Sciences, 2015
- [The effect of niacinamide on reducing cutaneous pigmentation and suppression of melanosome transfer](https://pubmed.ncbi.nlm.nih.gov/12100180/) Niacinamide · The British Journal of Dermatology, 2002
- [Skin delivery of epigallocatechin-3-gallate (EGCG) and hyaluronic acid loaded nano-transfersomes for antioxidant and anti-aging effects in UV radiation induced skin damage](https://pubmed.ncbi.nlm.nih.gov/28155509/) Sodium hyaluronate · Drug Delivery, 2017
- [Final report on the safety assessment of Benzyl Alcohol, Benzoic Acid, and Sodium Benzoate](https://pubmed.ncbi.nlm.nih.gov/11766131/) Benzyl alcohol · International Journal of Toxicology, 2001
- [Benefits of topical hyaluronic acid for skin quality and signs of skin aging: From literature review to clinical evidence](https://pubmed.ncbi.nlm.nih.gov/36200921/) Sodium hyaluronate, Hyaluronic acid · Dermatologic Therapy, 2022
- [Topical use of dexpanthenol in skin disorders](https://pubmed.ncbi.nlm.nih.gov/12113650/) Vitamin b5, Panthenol · American Journal of Clinical Dermatology, 2002
- [The Effect of Aloe Vera Clinical Trials on Prevention and Healing of Skin Wound: A Systematic Review](https://pubmed.ncbi.nlm.nih.gov/30666070/) Aloe barbadensis leaf extract · Iranian Journal of Medical Sciences, 2019
- [Improvement of naturally aged skin with vitamin A (retinol)](https://pubmed.ncbi.nlm.nih.gov/17515510/) Retinol · Archives of Dermatology, 2007
- [Final report on the safety assessment of BHT(1)](https://pubmed.ncbi.nlm.nih.gov/12396675/) Bht · International Journal of Toxicology, 2002
- [Anti-aging and brightening effects of a topical treatment containing vitamin C, vitamin E, and raspberry leaf cell culture extract: A split-face, randomized controlled trial](https://pubmed.ncbi.nlm.nih.gov/31975502/) Ascorbic acid, Tocopherol · Journal of Cosmetic Dermatology, 2020
- [Molecular basis of retinol anti-ageing properties in naturally aged human skin in vivo](https://pubmed.ncbi.nlm.nih.gov/27261203/) Retinol · International Journal of Cosmetic Science, 2017
- [Prospective, randomized, double-blind assessment of topical bakuchiol and retinol for facial photoageing](https://pubmed.ncbi.nlm.nih.gov/29947134/) Retinol, Bakuchiol · The British Journal of Dermatology, 2019
- [Effects of ascorbic acid on gingival melanin pigmentation in vitro and in vivo](https://pubmed.ncbi.nlm.nih.gov/19186973/) Ascorbyl glucoside · Journal of Periodontology, 2009
- [Apigenin inhibits UVA-induced cytotoxicity in vitro and prevents signs of skin aging in vivo](https://pubmed.ncbi.nlm.nih.gov/27279007/) Chamomilla recutita flower extract matricaria flower extract · International Journal of Molecular Medicine, 2016
- [Skin penetration and stabilization of formulations containing microfine titanium dioxide as physical UV filter](https://pubmed.ncbi.nlm.nih.gov/18503414/) Titanium dioxide · International Journal of Cosmetic Science, 2000
- [Treatment of acne with a combination of propolis, tea tree oil, and Aloe vera compared to erythromycin cream: two double-blind investigations](https://pubmed.ncbi.nlm.nih.gov/30588129/) Aloe barbadensis leaf juice, Aloe barbadensis leaf extract · Clinical Pharmacology, 2018
- [Topical benzoyl peroxide for acne](https://pubmed.ncbi.nlm.nih.gov/32175593/) Benzoyl peroxide · The Cochrane Database of Systematic Reviews, 2020
- [Sacha Inchi Oil (Plukenetia volubilis L.), effect on adherence of Staphylococus aureus to human skin explant and keratinocytes in vitro](https://pubmed.ncbi.nlm.nih.gov/26087228/) Plukenetia volubilis seed oil · Journal of Ethnopharmacology, 2015
- [Effect of a topical antioxidant serum containing vitamin C, vitamin E, and ferulic acid after Q-switched 1064-nm Nd:YAG laser for treatment of environment-induced skin pigmentation](https://pubmed.ncbi.nlm.nih.gov/32052907/) Ascorbic acid, Tocopherol · Journal of Cosmetic Dermatology, 2020
- [Design, characterization, and clinical evaluation of argan oil nanostructured lipid carriers to improve skin hydration](https://pubmed.ncbi.nlm.nih.gov/25143733/) Argania spinosa kernel oil argan kernel oil · International Journal of Nanomedicine, 2014
- [The 24-hour skin hydration and barrier function effects of a hyaluronic 1%, glycerin 5%, and Centella asiatica stem cells extract moisturizing fluid: an intra-subject, randomized, assessor-blinded study](https://pubmed.ncbi.nlm.nih.gov/28860834/) Glycerin · Clinical, Cosmetic and Investigational Dermatology, 2017
- [The human stratum corneum layer: an effective barrier against dermal uptake of different forms of topically applied micronised titanium dioxide](https://pubmed.ncbi.nlm.nih.gov/11509913/) Titanium dioxide · Skin Pharmacology and Applied Skin Physiology, 2001
- [Benzoyl peroxide treatment decreases Cutibacterium acnes in shoulder surgery, from skin incision until wound closure](https://pubmed.ncbi.nlm.nih.gov/33545336/) Benzoyl peroxide · Journal of Shoulder and Elbow Surgery, 2021
- [Randomized controlled study for the anti-aging effect of human adipocyte-derived mesenchymal stem cell media combined with niacinamide after laser therapy](https://pubmed.ncbi.nlm.nih.gov/33103316/) Niacinamide · Journal of Cosmetic Dermatology, 2021
- [Efficacy and Safety of a Fixed-Dose Clindamycin Phosphate 1.2%, Benzoyl Peroxide 3.1%, and Adapalene 0.15% Gel for Moderate-to-Severe Acne: A Randomized Phase II Study of the First Triple-Combination Drug](https://pubmed.ncbi.nlm.nih.gov/34674160/) Benzoyl peroxide · American Journal of Clinical Dermatology, 2022
- [Reduction in the appearance of facial hyperpigmentation by topical N-acetyl glucosamine](https://pubmed.ncbi.nlm.nih.gov/17348991/) Acetyl glucosamine, Neoglucosamine · Journal of Cosmetic Dermatology, 2007
- [Reduction in the appearance of facial hyperpigmentation after use of moisturizers with a combination of topical niacinamide and N-acetyl glucosamine: results of a randomized, double-blind, vehicle-controlled trial](https://pubmed.ncbi.nlm.nih.gov/19845667/) Acetyl glucosamine, Neoglucosamine · The British Journal of Dermatology, 2010
- [Quaternized carboxymethyl chitosan/organic montmorillonite nanocomposite as a novel cosmetic ingredient against skin aging](https://pubmed.ncbi.nlm.nih.gov/28732847/) Bentonite · Carbohydrate Polymers, 2017
- [A new topical panthenol-containing emollient: Results from two randomized controlled studies assessing its skin moisturization and barrier restoration potential, and the effect on skin microflora](https://pubmed.ncbi.nlm.nih.gov/27425824/) Vitamin b5, Panthenol · The Journal of Dermatological Treatment, 2017
- [Phytosphingosine enhances moisture level in human skin barrier through stimulation of the filaggrin biosynthesis and degradation leading to NMF formation](https://pubmed.ncbi.nlm.nih.gov/28936777/) Hydration complex · Archives of Dermatological Research, 2017
- [A Double-Blinded, Randomized, Vehicle-Controlled Study of the Efficacy of Moisturizer Containing Licochalcone A, Decanediol, L-Carnitine, and Salicylic Acid for Prevention of Acne Relapse in Asian Population](https://pubmed.ncbi.nlm.nih.gov/33150170/) Salicylic acid, Microclear technology · BioMed Research International, 2020
- [Senomorphic activity of a combination of niacinamide and hyaluronic acid: correlation with clinical improvement of skin aging](https://pubmed.ncbi.nlm.nih.gov/39009698/) Niacinamide · Scientific Reports, 2024
- [Efficacy of a topical gel containing chitosan, chlorhexidine, allantoin and dexpanthenol for pain and inflammation control after third molar surgery: A randomized and placebo-controlled clinical trial](https://pubmed.ncbi.nlm.nih.gov/32683390/) Allantoin · Medicina Oral, Patologia Oral Y Cirugia Bucal, 2020
- [High molecular compounds (polysaccharides and proanthocyanidins) from Hamamelis virginiana bark: influence on human skin keratinocyte proliferation and differentiation and influence on irritated skin](https://pubmed.ncbi.nlm.nih.gov/11684194/) Witch hazel extract · Phytochemistry, 2001
- [The efficacy of glycolic acid, salicylic acid, gluconolactone, and licochalcone A combined with 0.1% adapalene vs adapalene monotherapy in mild-to-moderate acne vulgaris: a double-blinded within-person comparative study](https://pubmed.ncbi.nlm.nih.gov/30858720/) Glycolic acid · Clinical, Cosmetic and Investigational Dermatology, 2019
- [A comparative study of gluconolactone versus benzoyl peroxide in the treatment of acne](https://pubmed.ncbi.nlm.nih.gov/1303072/) Gluconolactone · The Australasian Journal of Dermatology, 1992
- [Anti-inflammatory activity of parthenolide-depleted Feverfew (Tanacetum parthenium)](https://pubmed.ncbi.nlm.nih.gov/19112586/) Chrysanthemum parthenium flower leaf stem juice · Inflammopharmacology, 2009
- [Efficacy of a multitargeted, salicylic acid-based dermocosmetic cream compared to benzoyl peroxide 5% in Acne vulgaris: Results from a randomized study](https://pubmed.ncbi.nlm.nih.gov/37941097/) Salicylic acid, Microclear technology · Journal of Cosmetic Dermatology, 2024
- [Biomimetic hyaluronic acid-stabilized zinc oxide nanoparticles in acne treatment: A preclinical and clinical approach](https://pubmed.ncbi.nlm.nih.gov/40254135/) Zinc oxide · Journal of Controlled Release, 2025
- [Efficacy and Tolerability of a Skin Brightening/Anti-Aging Cosmeceutical Containing Retinol 0.5%, Niacinamide, Hexylresorcinol, and Resveratrol](https://pubmed.ncbi.nlm.nih.gov/27391637/) Hexylresorcinol · Journal of Drugs in Dermatology, 2016
- [Comparison of clinical efficacies of sodium ascorbyl phosphate, retinol and their combination in acne treatment](https://pubmed.ncbi.nlm.nih.gov/19134126/) Sodium ascorbyl phosphate · International Journal of Cosmetic Science, 2009
- [Preparation and evaluation of benzalkonium chloride hand sanitizer as a potential alternative for alcohol-based hand gels](https://pubmed.ncbi.nlm.nih.gov/34408542/) Benzalkonium chloride · Saudi Pharmaceutical Journal, 2021
- [Retaining Skin Barrier Function Properties of the Stratum Corneum with Components of the Natural Moisturizing Factor-A Randomized, Placebo-Controlled Double-Blind In Vivo Study](https://pubmed.ncbi.nlm.nih.gov/33809557/) Hydration complex · Molecules, 2021
- [Superior even skin tone and anti-ageing benefit of a combination of 4-hexylresorcinol and niacinamide](https://pubmed.ncbi.nlm.nih.gov/34958693/) Hexylresorcinol · International Journal of Cosmetic Science, 2022
- [Efficacy and safety of microencapsulated benzoyl peroxide and microencapsulated tretinoin for the treatment of acne vulgaris: Results from two phase 3 double-blind, randomized, vehicle-controlled studies](https://pubmed.ncbi.nlm.nih.gov/37356627/) Benzoyl peroxide · Journal of the American Academy of Dermatology, 2023
- [A Salicylic Acid-Based Dermocosmetic is Effective as an Adjunct to Benzoyl Peroxide for Mild to Moderate Acne and as Monotherapy in Maintenance Post Benzoyl Peroxide](https://pubmed.ncbi.nlm.nih.gov/38051857/) Salicylic acid, Microclear technology · Journal of Drugs in Dermatology, 2023
- [Efficacy and tolerability of the investigational topical cream SD-101 (6% allantoin) in patients with epidermolysis bullosa: a phase 3, randomized, double-blind, vehicle-controlled trial (ESSENCE study)](https://pubmed.ncbi.nlm.nih.gov/32576219/) Allantoin · Orphanet Journal of Rare Diseases, 2020
- [Botulinum toxin injection as a single or combined treatment with non-cross-linked high molecular weight and low molecular weight hyaluronic acid gel for neck rejuvenation: A randomized clinical trial](https://pubmed.ncbi.nlm.nih.gov/35775872/) Hydrolyzed hyaluronic acid · Dermatologic Therapy, 2022
- [Subclinical, non-erythematous irritation with an open assay model (washing): sodium lauryl sulfate (SLS) versus sodium laureth sulfate (SLES)](https://pubmed.ncbi.nlm.nih.gov/11278060/) Sodium laureth sulfate · Food and Chemical Toxicology, 2001
- [Challenging the safety and efficacy of topically applied chlorogenic acid, apigenin, kaempferol, and naringenin by HET-CAM, HPLC-TBARS-EVSC, and laser Doppler flowmetry](https://pubmed.ncbi.nlm.nih.gov/38831914/) Grapefruit extract · Frontiers in Chemistry, 2024
- [Safety assessment of cyclomethicone, cyclotetrasiloxane, cyclopentasiloxane, cyclohexasiloxane, and cycloheptasiloxane](https://pubmed.ncbi.nlm.nih.gov/22247236/) Cyclopentasiloxane · International Journal of Toxicology, 2011
- [Is benzyl alcohol a significant contact sensitizer?](https://pubmed.ncbi.nlm.nih.gov/35080274/) Benzyl alcohol · Journal of the European Academy of Dermatology and Venereology, 2022
- [Evaluation of moisturizing and irritation potential of sacha inchi oil](https://pubmed.ncbi.nlm.nih.gov/31441999/) Plukenetia volubilis seed oil · Journal of Cosmetic Dermatology, 2020
- [Whitening effect of alpha-bisabolol in Asian women subjects](https://pubmed.ncbi.nlm.nih.gov/20642768/) Bisabolol · International Journal of Cosmetic Science, 2010
- [Clinical evaluation of the efficacy of a facial serum containing dioic acid, glycolic acid, salicylic acid, LHA, citric acid, and HEPES in treating post-inflammatory hyperchromia and controlling oily skin in patients with acne vulgaris](https://pubmed.ncbi.nlm.nih.gov/33617668/) Citric acid · Journal of Cosmetic Dermatology, 2021
- [Parthenolide-depleted Feverfew (Tanacetum parthenium) protects skin from UV irradiation and external aggression](https://pubmed.ncbi.nlm.nih.gov/18071724/) Chrysanthemum parthenium flower leaf stem juice · Archives of Dermatological Research, 2008
- [Assessment of Combined Ascorbyl Palmitate (AP) and Sodium Ascorbyl Phosphate (SAP) on Facial Skin Sebum Control in Female Healthy Volunteers](https://pubmed.ncbi.nlm.nih.gov/27756097/) Sodium ascorbyl phosphate · Drug Research, 2017
- [Solid lipid nanoparticles bearing oxybenzone: in-vitro and in-vivo evaluation](https://pubmed.ncbi.nlm.nih.gov/19622017/) Oxybenzone, Oxybenzone-free formula · Journal of Microencapsulation, 2010
- [Nanostructured Lipid Carrier for Topical Application of N-Acetyl Glucosamine](https://pubmed.ncbi.nlm.nih.gov/28101465/) Acetyl glucosamine, Neoglucosamine · Advanced Pharmaceutical Bulletin, 2016
- [Axillary hyperhidrosis. Local treatment with aluminium-chloride hexahydrate 25% in absolute ethanol with and without supplementary treatment with triethanolamine](https://pubmed.ncbi.nlm.nih.gov/2449022/) Triethanolamine · Acta Dermato-venereologica, 1988
- [Using ordered mesoporous silica SBA-15 to limit cutaneous penetration and transdermal permeation of organic UV filters](https://pubmed.ncbi.nlm.nih.gov/31437563/) Oxybenzone-free formula · International Journal of Pharmaceutics, 2019
- [Enhancing Photoprotection and Mitigating Ex Vivo Stratum Corneum Oxidative Stress: A Multifunctional Strategy Combining Rosmarinic Acid with UVB Filters](https://pubmed.ncbi.nlm.nih.gov/40227214/) Octocrylene · Antioxidants, 2025
- [Rates of allergic sensitization and irritation to oxybenzone-containing sunscreen products: a quantitative meta-analysis of 64 exaggerated use studies](https://pubmed.ncbi.nlm.nih.gov/18717962/) Helioplex technology, Helioplex · Photodermatology, Photoimmunology & Photomedicine, 2008
- [Influence of vitamin E acetate on stratum corneum hydration](https://pubmed.ncbi.nlm.nih.gov/9706379/) Tocopheryl acetate vitamin e, Tocopheryl acetate · Arzneimittel-Forschung, 1998
- [Topical Zinc Oxide Nanoparticle Formulations for Acne Vulgaris: A Systematic Review of Pre-Clinical and Early-Phase Clinical Evidence](https://pubmed.ncbi.nlm.nih.gov/41007718/) Zinc oxide · Biomedicines, 2025
- [A controlled, three-part trial to investigate the barrier function and skin hydration properties of six skin protectants](https://pubmed.ncbi.nlm.nih.gov/16439809/) Dimethicone · Ostomy/wound Management, 2005
- [Comparative physicochemical stability and clinical anti-wrinkle efficacy of transdermal emulgel preparations of 5% sodium ascorbyl phosphate and or ascorbic acid on human volunteers](https://pubmed.ncbi.nlm.nih.gov/32383548/) Sodium ascorbyl phosphate · Journal of Cosmetic Dermatology, 2021
- [TiO2-embedded mesoporous silica with lower porosity is beneficial to adsorb the pollutants and retard UV filter absorption: A possible application for outdoor skin protection](https://pubmed.ncbi.nlm.nih.gov/36455708/) Avobenzone · European Journal of Pharmaceutical Sciences, 2023
- [A new formula for a mild body cleanser: sodium laureth sulphate supplemented with sodium laureth carboxylate and lauryl glucoside](https://pubmed.ncbi.nlm.nih.gov/24617572/) Lauryl glucoside · International Journal of Cosmetic Science, 2014
- [Evaluation of the Efficacy and Safety of a Panthenol-Enriched Mask for Skin Barrier Recovery After Facial Laser Treatment: Results of a Double-Blind Randomized Controlled Study](https://pubmed.ncbi.nlm.nih.gov/40613435/) Vitamin b5, Panthenol · Journal of Cosmetic Dermatology, 2025
- [Safety of a preservative system containing 1,2-hexanediol and caprylyl glycol](https://pubmed.ncbi.nlm.nih.gov/19514921/) Caprylyl glycol · Cutaneous and Ocular Toxicology, 2009
- [Cucumber (Cucumis sativus L.) with heterologous poly-γ-glutamic acid has skin moisturizing, whitening and anti-wrinkle effects](https://pubmed.ncbi.nlm.nih.gov/38336313/) Cucumis sativus fruit extract · International Journal of Biological Macromolecules, 2024
- [Efficacy and Tolerability of Stable Hybrid Cooperative Complexes of High- and Low-Molecular Weight Hyaluronic Acid in Asian Patients: An Open-Label Study](https://pubmed.ncbi.nlm.nih.gov/40921777/) Hydrolyzed hyaluronic acid · Aesthetic Plastic Surgery, 2026
- [Prospective, randomized, double-blind clinical study of split-body comparison of topical hydroquinone and hexylresorcinol for skin pigment appearance](https://pubmed.ncbi.nlm.nih.gov/36502500/) Hexylresorcinol · Archives of Dermatological Research, 2023
- [Instrumental, clinical and subjective evaluation of the efficacy of a cosmetic treatment for home use](https://pubmed.ncbi.nlm.nih.gov/30040516/) Acetyl glucosamine, Neoglucosamine · Journal of Cosmetic and Laser Therapy, 2019
- [Nanocomplex of quaternized cyclodextrin grafted chitosan and hyaluronic acid for a skin delivery](https://pubmed.ncbi.nlm.nih.gov/36279763/) Hydrolyzed hyaluronic acid · Colloids and Surfaces. B, Biointerfaces, 2022
- [Functional properties and skin care effects of sodium trehalose sulfate](https://pubmed.ncbi.nlm.nih.gov/38606717/) Trehalose · Skin Research and Technology, 2024
- [A Double-Blind, 12-Week Study to Evaluate the Antiaging Efficacy of a Cream Containing the NFκB Inhibitor 4-Hexyl-1, 3-Phenylenediol and Ascorbic Acid-2 Glucoside in Adult Females](https://pubmed.ncbi.nlm.nih.gov/27272084/) Ascorbyl glucoside · Journal of Drugs in Dermatology, 2016
- [Nanostructured Lipid Carrier Based Gel Containing α-Tocopherol and α-Tocopheryl Acetate for Synergistic Cutaneous Antiaging Efficacy](https://pubmed.ncbi.nlm.nih.gov/41309687/) Tocopheryl acetate · Scientific Reports, 2025
- [Evaulation of irritation potential of surfactant mixtures](https://pubmed.ncbi.nlm.nih.gov/18503452/) Sodium laureth sulfate · International Journal of Cosmetic Science, 1999
- [Comparison of clindamycin 1% and benzoyl peroxide 5% gel to a novel composition containing salicylic acid, capryloyl salicylic acid, HEPES, glycolic acid, citric acid, and dioic acid in the treatment of acne vulgaris](https://pubmed.ncbi.nlm.nih.gov/23545907/) Citric acid · Journal of Drugs in Dermatology, 2013
- [Facial disbiosis and UV filters](https://pubmed.ncbi.nlm.nih.gov/39499337/) Octocrylene · Archives of Dermatological Research, 2024
- [A Randomized Controlled Trial of the Genistein Plus Bakuchiol and Vitamins (GEN+) Product for Male Facial Skin: Effects on Skin Appearance and Properties](https://pubmed.ncbi.nlm.nih.gov/41562471/) Bakuchiol · Skin Research and Technology, 2026
- [Treatment with Ascorbyl Glucoside-Arginine Complex Ameliorates Solar Lentigos](https://pubmed.ncbi.nlm.nih.gov/39769217/) Ascorbyl glucoside · International Journal of Molecular Sciences, 2024
- [Safety assessment on comedogenicity of dermatological products containing d-alpha tocopheryl acetate in Asian subjects: A double-blind randomized controlled trial](https://pubmed.ncbi.nlm.nih.gov/34471722/) Tocopheryl acetate · Contemporary Clinical Trials Communications, 2021
- [Portulaca oleracea extract relieves skin barrier damage induced by increased photosensitivity after GA peeling](https://pubmed.ncbi.nlm.nih.gov/35920724/) Portulaca oleracea extract · Cutaneous and Ocular Toxicology, 2022
- [Retrospective Review of Dermal Safety Studies of Organic Sunscreens](https://pubmed.ncbi.nlm.nih.gov/40911743/) Homosalate, Octisalate, Ethylhexyl salicylate · Journal of Drugs in Dermatology, 2025
- [Acetyl Dipeptide-31 Amide: A Novel Cosmetic Anti-Inflammatory Peptide That Demonstrates Anti-Aging, Firming, and Lifting Benefits](https://pubmed.ncbi.nlm.nih.gov/39761149/) Acetyl dipeptide-31 amide · Journal of Drugs in Dermatology, 2025
- [Natural Moisturizing Factor-Enriched Formulations Compared to a Ceramide-Based Cream](https://pubmed.ncbi.nlm.nih.gov/38443132/) Hydration complex · Journal of Drugs in Dermatology, 2024
- [Synergistic combination: Developing a natural carrier-free assembled gel through hydrogen bond reconstruction strategy for efficient skin photo-damage restoration](https://pubmed.ncbi.nlm.nih.gov/41129958/) Sodium pca · Biomaterials Advances, 2026
- [Clinical Efficacy of Topical Ascorbic Acid 2-Glucoside in Enhancing Outcomes of Laser Gingival Depigmentation: A Randomized Controlled Trial](https://pubmed.ncbi.nlm.nih.gov/42147661/) Ascorbyl glucoside · Cureus, 2026
- [Efficacy and safety of combination cream of stimu-tex AS™ (spent grain wax, Argania Spinosa Kernel oil, Butyrospermum Parkii (shea butter) extract), and saccharide isomerate after fractional CO2 laser procedure: split-face, double blinded, randomized controlled trial](https://pubmed.ncbi.nlm.nih.gov/41134387/) Butyrospermum parkii butter shea butter · Lasers in Medical Science, 2025
- [The Therapeutic Effects of a Bentonite-Based Facial Mask With Alcea sulphurea Extract on Acne Severity and Patient Experience: Add-On Randomized Controlled Clinical Trial](https://pubmed.ncbi.nlm.nih.gov/41347526/) Bentonite · Journal of Cosmetic Dermatology, 2025
- [Impact of dermal emulsions containing diacyl phospholipids, mono acyl phospholipids, sodium lauryl ether sulfate and polysorbate 80 in combination with UVA irradiation on human skin physiology in vivo: A pilot study](https://pubmed.ncbi.nlm.nih.gov/42617898/) Sodium laureth sulfate · International Journal of Pharmaceutics, 2026
- [Split-face evaluation: Gluconolactone plus oxybrasion versus gluconolactone plus microneedling. The effects on skin parameters](https://pubmed.ncbi.nlm.nih.gov/37357656/) Gluconolactone · Skin Research and Technology, 2023
- [Low-temperature extracted Portulaca oleracea L. as a functional ingredient in facial masks for photorejuvenation of sensitive skin](https://pubmed.ncbi.nlm.nih.gov/41182319/) Portulaca oleracea extract · Cutaneous and Ocular Toxicology, 2025

## The brands

- American skincare: [Neutrogena](https://lovi.care/skincare/sg/brands/neutrogena)
- Skincare: [FRE](https://lovi.care/skincare/sg/brands/fre)

## More comparisons

- [SKIN1004 vs Neutrogena](https://lovi.care/skincare/sg/compare/skin1004-vs-neutrogena)
- [SKIN1004 vs FRE](https://lovi.care/skincare/sg/compare/skin1004-vs-fre)
- [Anua vs Neutrogena](https://lovi.care/skincare/sg/compare/anua-vs-neutrogena)
- [Anua vs FRE](https://lovi.care/skincare/sg/compare/anua-vs-fre)
- [Medicube vs Neutrogena](https://lovi.care/skincare/sg/compare/medicube-vs-neutrogena)
- [Medicube vs FRE](https://lovi.care/skincare/sg/compare/medicube-vs-fre)
- [The Ordinary vs Neutrogena](https://lovi.care/skincare/sg/compare/the-ordinary-vs-neutrogena)
- [The Ordinary vs FRE](https://lovi.care/skincare/sg/compare/the-ordinary-vs-fre)
- [Beauty of Joseon vs Neutrogena](https://lovi.care/skincare/sg/compare/beauty-of-joseon-vs-neutrogena)
- [Beauty of Joseon vs FRE](https://lovi.care/skincare/sg/compare/beauty-of-joseon-vs-fre)
- [COSRX vs Neutrogena](https://lovi.care/skincare/sg/compare/cosrx-vs-neutrogena)
- [COSRX vs FRE](https://lovi.care/skincare/sg/compare/cosrx-vs-fre)
- [CeraVe vs Neutrogena](https://lovi.care/skincare/sg/compare/cerave-vs-neutrogena)
- [CeraVe vs FRE](https://lovi.care/skincare/sg/compare/cerave-vs-fre)
- [La Roche-Posay vs Neutrogena](https://lovi.care/skincare/sg/compare/la-roche-posay-vs-neutrogena)
- [La Roche-Posay vs FRE](https://lovi.care/skincare/sg/compare/la-roche-posay-vs-fre)
- [Dr. Althea vs Neutrogena](https://lovi.care/skincare/sg/compare/dr-althea-vs-neutrogena)
- [Dr. Althea vs FRE](https://lovi.care/skincare/sg/compare/dr-althea-vs-fre)
- [Some By Mi vs Neutrogena](https://lovi.care/skincare/sg/compare/some-by-mi-vs-neutrogena)
- [Some By Mi vs FRE](https://lovi.care/skincare/sg/compare/some-by-mi-vs-fre)

## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this comparison: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/compare/neutrogena-vs-fre
- United Kingdom: https://lovi.care/skincare/uk/compare/neutrogena-vs-fre
- Ireland: https://lovi.care/skincare/ie/compare/neutrogena-vs-fre
- Germany: https://lovi.care/skincare/de/compare/neutrogena-vs-fre
- France: https://lovi.care/skincare/fr/compare/neutrogena-vs-fre
- Italy: https://lovi.care/skincare/it/compare/neutrogena-vs-fre
- Netherlands: https://lovi.care/skincare/nl/compare/neutrogena-vs-fre
- Spain: https://lovi.care/skincare/es/compare/neutrogena-vs-fre
- Canada: https://lovi.care/skincare/ca/compare/neutrogena-vs-fre
- Australia: https://lovi.care/skincare/au/compare/neutrogena-vs-fre
- Singapore: https://lovi.care/skincare/sg/compare/neutrogena-vs-fre (this page)
- Saudi Arabia: https://lovi.care/skincare/sa/compare/neutrogena-vs-fre
- United Arab Emirates: https://lovi.care/skincare/ae/compare/neutrogena-vs-fre