# Good Molecules vs Shiseido

Page: https://lovi.care/skincare/sg/compare/good-molecules-vs-shiseido

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Singapore.

Good Molecules and Shiseido are a 2019 American skincare brand owned by Beautylish, Inc. and an 1872 Japanese skincare brand owned by Shiseido Company, Limited, respectively. The former is widely loved for its thoughtful range of [serums](https://lovi.care/skincare/sg/ingredients/serum), moisturizers, eye products, exfoliants, and more, which are formulated with key ingredients like [glycerin](https://lovi.care/skincare/sg/ingredients/glycerin) and [hyaluronic acid](https://lovi.care/skincare/sg/ingredients/hyaluronic-acid), while the latter is beloved for its thoughtful array of moisturizers, cleansers, sunscreens, serums, and more, all formulated with key ingredients like glycerin. Good Molecules suits combination skin and oily acne-prone skin best, whereas the brand from Japan suits sensitive skin and mature skin best, offering gentle yet effective daily care. They differ primarily in their specific target audiences and distinct ingredient profiles, as the American line utilizes glycerin to improve skin hydration and restore barrier function alongside hyaluronic acid to lengthen the effect of wrinkle-reducing toxins, while the Japanese line relies on glycerin, which clinical study findings show significantly improved stratum corneum hydration.

Good Molecules is an American skincare brand founded in 2019 and owned by Beautylish, Inc..

[beautymatter.com](https://beautymatter.com/articles/aria-growth-partners-makes-investment-in-good-molecules) [goodmolecules.com](https://www.goodmolecules.com/about) [pitchbook.com](https://pitchbook.com/profiles/company/458272-45) [preqin.com](https://www.preqin.com/data/profile/asset/good-molecules--llc-/802471)

Shiseido is a Japanese skincare brand founded in 1872 and owned by Shiseido Company, Limited.

[corp.shiseido.com](https://corp.shiseido.com/en/company/info/) [en.wikipedia.org](https://en.wikipedia.org/wiki/Shiseido) [marketscreener.com](https://www.marketscreener.com/quote/stock/SHISEIDO-COMPANY-LIMITED-6492328/news/Shiseido-Company-Limited-Announces-CEO-Changes-Effective-January-1-2025-47501230/)

This page compares some of the most popular Good Molecules and Shiseido products; for every product of both brands, with a fit score for your own skin, [use the Lovi app](https://app.pora.ai/vqqJ/j1xj2b6o?af_sub2=compare&af_sub3=selection_note&af_sub4=pg9628a14780).

### Popular Good Molecules vs Shiseido products

#### Good Molecules

- [Discoloration Correcting Serum](https://lovi.care/skincare/sg/p/good-molecules/discoloration-correcting-serum/for/dry-skin) — High fit — [S$56.22 at Amazon](https://www.amazon.sg/dp/B0BX32CXP6?tag=lovi-care-web-product0e-22&linkCode=osi&th=1&psc=1)
- [Hyaluronic Acid Serum](https://lovi.care/skincare/sg/p/good-molecules/hyaluronic-acid-serum/for/dry-skin) — Superior fit
- [Gentle Retinol Cream](https://lovi.care/skincare/sg/p/good-molecules/gentle-retinol-cream/for/mature-skin) — High fit
- [Niacinamide Serum](https://lovi.care/skincare/sg/p/good-molecules/niacinamide-serum/for/oily-skin) — Average fit — [S$56.22 at Amazon](https://www.amazon.sg/dp/B0BX32CXP6?tag=lovi-care-web-product0e-22&linkCode=osi&th=1&psc=1)
- [Niacinamide Brightening Toner](https://lovi.care/skincare/sg/p/good-molecules/niacinamide-brightening-toner/for/dry-skin) — High fit
- [PIMPLE PATCHES](https://lovi.care/skincare/sg/p/good-molecules/pimple-patches/for/acne-prone-skin) — Average fit
- [Yerba Mate Wake Up Eye Gel](https://lovi.care/skincare/sg/p/good-molecules/yerba-mate-wake-up-eye-gel/for/mature-skin) — Superior fit
- [Lightweight Daily Moisturizer](https://lovi.care/skincare/sg/p/good-molecules/lightweight-daily-moisturizer/for/dry-skin) — Superior fit

#### Shiseido

- [Benefiance Wrinkle Smoothing Eye Cream](https://lovi.care/skincare/sg/p/shiseido/benefiance-wrinkle-smoothing-eye-cream/for/mature-skin) — High fit — [S$55.43 at YesStyle](https://www.yesstyle.com/en/shiseido-benefiance-wrinkle-smoothing-eye-cream-international-edition/info.html/pid.1137782181?curr=SGD&rco=SG)
- [Ultimune Power Infusing Concentrate](https://lovi.care/skincare/sg/p/shiseido/ultimune-power-infusing-concentrate/for/sensitive-skin) — Average fit — [S$9.25 at YesStyle](https://www.yesstyle.com/en/shiseido-ultimune-power-infusing-serum-10ml/info.html/pid.1129827910?curr=SGD&rco=SG)
- [VITAL PERFECTION](https://lovi.care/skincare/sg/p/shiseido/vital-perfection/for/mature-skin) — Average fit — [S$124.16 at Amazon](https://www.amazon.sg/dp/B008BEK3PE?tag=lovi-care-web-product0e-22&linkCode=osi&th=1&psc=1)
- [Clarifying Cleansing Foam](https://lovi.care/skincare/sg/p/shiseido/clarifying-cleansing-foam/for/mature-skin) — Average fit — [S$54.05 at Amazon](https://www.amazon.sg/dp/B07Q2HNRTB?tag=lovi-care-web-product0e-22&linkCode=osi&th=1&psc=1)
- [Essential Energy Hydrating Cream](https://lovi.care/skincare/sg/p/shiseido/essential-energy-hydrating-cream/for/mature-skin) — Superior fit — [S$78.82 at Amazon](https://www.amazon.sg/dp/B09SBSPXTY?tag=lovi-care-web-product0e-22&linkCode=osi&th=1&psc=1)
- [Activating Essence](https://lovi.care/skincare/sg/p/shiseido/activating-essence/for/dry-skin) — High fit
- [FUTURE SOLUTION LX](https://lovi.care/skincare/sg/p/shiseido/future-solution-lx/for/sensitive-skin) — High fit
- [Bio-Performance Advanced Super Revitalizing Cream](https://lovi.care/skincare/sg/p/shiseido/bio-performance-advanced-super-revitalizing-cream/for/dry-skin) — Warning fit — [S$161.49 at Amazon](https://www.amazon.sg/dp/B0002JBQFW?tag=lovi-care-web-product0e-22&linkCode=osi&th=1&psc=1)

## People Say

Good Molecules

Shiseido

- Deep hydration and moisture Often Mentioned Mostly Mentioned “Immediate sensation of comfort — Shiseido Benefiance Wrinkle Smoothing Eye Cream” “skin feels plump, soft and nourished, eliminates dryness, bouncy feel — Shiseido VITAL PERFECTION” “Skin feels more hydrated — Shiseido Activating Essence” “skin appears smooth and supple — Good Molecules Hyaluronic Acid Serum”
- Affordable price and great value Mostly Mentioned Not noted “best value for money — Good Molecules Hyaluronic Acid Serum” “great value — Good Molecules Niacinamide Serum”
- Luxurious and elegant texture Sometimes Noted Often Mentioned “silky smooth, rich but non-greasy, absorbs quickly, melts into skin — Shiseido VITAL PERFECTION” “Velvety, rich cream texture — Shiseido Benefiance Wrinkle Smoothing Eye Cream” “Velvety texture — Shiseido FUTURE SOLUTION LX” “absorbs almost instantly — Good Molecules Hyaluronic Acid Serum”
- Brightening and radiant glow Sometimes Noted Often Mentioned “Skin looks brighter, more radiant, and "glowy." — Shiseido Ultimune Power Infusing Concentrate” “faded pimple marks — Shiseido White Lucent Brightening Gel Cream” “Eyes look more awake — Shiseido Benefiance Wrinkle Smoothing Eye Cream” “skin looks more radiant — Good Molecules Niacinamide Brightening Toner”
- Improves skin texture and smoothness Often Mentioned Sometimes Noted “skin looks like brand new baby skin — Good Molecules Overnight Exfoliating Treatment” “Leaves skin "baby soft," "super smooth," "polished feel" — Good Molecules Pineapple Exfoliating Powder” “softened fine lines — Good Molecules Gentle Retinol Cream” “makes skin baby soft — Shiseido Benefiance Wrinkle Smoothing Cream Enriched”
- Lightweight and non-greasy texture Sometimes Noted Sometimes Noted “absorbs quickly... zero irritation or tacky feeling — Good Molecules Discoloration Correcting Serum” “absorbs instantly into skin — Good Molecules Lightweight Daily Moisturizer” “Airy-soft texture — Shiseido Essential Energy Hydrating Cream” “absorbs quickly — Shiseido White Lucent Brightening Gel Cream”
- High price point Not noted Mostly Mentioned “Very expensive for the size — Shiseido Benefiance Wrinkle Smoothing Eye Cream”
- Strong fragrance and scent complaints Sometimes Noted Often Mentioned “Strong bergamot smell — Good Molecules Super Peptide Serum” “weird faint smell — Good Molecules Gentle Retinol Cream” “smelled of glycolic acid — Good Molecules Overnight Exfoliating Treatment” “old lady smell — Shiseido Eudermine Revitalizing Essence”
- Packaging issues and design Sometimes Noted Sometimes Noted “Metal tube cracks — Good Molecules Yerba Mate Wake Up Eye Gel” “Hole is too big — Good Molecules Pineapple Exfoliating Powder” “heavy to travel — Shiseido Eudermine Revitalizing Essence” “Heavy bottle but plastic pump, cannot see remaining product, straw too short to get last drops. — Shiseido Ultimune Power Infusing Concentrate”

### Good Molecules vs Shiseido routines for dry skin

#### Good Molecules-focused routine

- Cleanser: [CeraVe Hydrating Facial Cleanser](https://lovi.care/skincare/sg/p/cerave/hydrating-facial-cleanser/for/dry-skin) — Superior fit — [S$25.06 at Amazon](https://www.amazon.sg/dp/B07RL88DD2?tag=lovi-care-web-routine07-22&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- Hydrating Toner: [COSRX Propolis Synergy Toner](https://lovi.care/skincare/sg/p/cosrx/propolis-synergy-toner/for/dry-skin) — Superior fit — [S$41.07 at Amazon](https://www.amazon.sg/dp/B07XHHRXDZ?tag=lovi-care-web-routine07-22&linkCode=osi&th=1&psc=1) — Morning
- Moisturizer: [d'Alba First Spray Serum](https://lovi.care/skincare/sg/p/d-alba/first-spray-serum/for/dry-skin) — Superior fit — [S$25.94 at Amazon](https://www.amazon.sg/dp/B0C5T25JJP?tag=lovi-care-web-routine07-22&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- SPF: [thinkbaby Safe Sunscreen SPF 50+](https://lovi.care/skincare/sg/p/thinkbaby/safe-sunscreen-spf-50/for/dry-skin) — Superior fit — [S$21.09 at Amazon](https://www.amazon.sg/dp/B007SAC6XE?tag=lovi-care-web-routine07-22&linkCode=osi&th=1&psc=1) — Morning
- Pre-Cleanser: [MISSHA Ultra Hyalon Cleansing Cream](https://lovi.care/skincare/sg/p/missha/ultra-hyalon-cleansing-cream/for/dry-skin) — Superior fit — [S$39.68 at Amazon](https://www.amazon.sg/dp/B084Q16G8D?tag=lovi-care-web-routine07-22&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Serum or Treatment: [Discoloration Correcting Serum](https://lovi.care/skincare/sg/p/good-molecules/discoloration-correcting-serum/for/dry-skin) — High fit — [S$56.22 at Amazon](https://www.amazon.sg/dp/B0BX32CXP6?tag=lovi-care-web-routine07-22&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Nourishing Mask: [MEDIHEAL Collagen Essential Mask](https://lovi.care/skincare/sg/p/mediheal/collagen-essential-mask/for/dry-skin) — Superior fit — [S$62.94 at Amazon](https://www.amazon.sg/dp/B0DDBDYZWN?tag=lovi-care-web-routine07-22&linkCode=osi&th=1&psc=1) — Once a week

#### Shiseido-focused routine

- Cleanser: [Clarifying Cleansing Foam](https://lovi.care/skincare/sg/p/shiseido/clarifying-cleansing-foam/for/dry-skin) — Caution fit — [S$54.05 at Amazon](https://www.amazon.sg/dp/B07Q2HNRTB?tag=lovi-care-web-routine07-22&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- Hydrating Toner: [Eudermine Revitalizing Essence](https://lovi.care/skincare/sg/p/shiseido/eudermine-revitalizing-essence/for/dry-skin) — Average fit — [S$112.11 at YesStyle](https://www.yesstyle.com/en/shiseido-eudermine-revitalizing-essence-200ml/info.html/pid.1076117866?curr=SGD&rco=SG) — Morning
- Moisturizer: [Essential Energy Hydrating Cream](https://lovi.care/skincare/sg/p/shiseido/essential-energy-hydrating-cream/for/dry-skin) — High fit — [S$78.82 at Amazon](https://www.amazon.sg/dp/B09SBSPXTY?tag=lovi-care-web-routine07-22&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- SPF: [thinkbaby Safe Sunscreen SPF 50+](https://lovi.care/skincare/sg/p/thinkbaby/safe-sunscreen-spf-50/for/dry-skin) — Superior fit — [S$21.09 at Amazon](https://www.amazon.sg/dp/B007SAC6XE?tag=lovi-care-web-routine07-22&linkCode=osi&th=1&psc=1) — Morning
- Pre-Cleanser: [MISSHA Ultra Hyalon Cleansing Cream](https://lovi.care/skincare/sg/p/missha/ultra-hyalon-cleansing-cream/for/dry-skin) — Superior fit — [S$39.68 at Amazon](https://www.amazon.sg/dp/B084Q16G8D?tag=lovi-care-web-routine07-22&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Serum or Treatment: [Ultimune Power Infusing Concentrate](https://lovi.care/skincare/sg/p/shiseido/ultimune-power-infusing-concentrate/for/dry-skin) — Low fit — [S$9.25 at YesStyle](https://www.yesstyle.com/en/shiseido-ultimune-power-infusing-serum-10ml/info.html/pid.1129827910?curr=SGD&rco=SG) — Evening · Once a week
- Nourishing Mask: [MEDIHEAL Collagen Essential Mask](https://lovi.care/skincare/sg/p/mediheal/collagen-essential-mask/for/dry-skin) — Superior fit — [S$62.94 at Amazon](https://www.amazon.sg/dp/B0DDBDYZWN?tag=lovi-care-web-routine07-22&linkCode=osi&th=1&psc=1) — Once a week

[Buy Good Molecules routine · S$272.00 · 96% fit](https://www.amazon.sg/gp/aws/cart/add.html?ASIN.1=B07RL88DD2&Quantity.1=1&ASIN.2=B07XHHRXDZ&Quantity.2=1&ASIN.3=B0C5T25JJP&Quantity.3=1&ASIN.4=B007SAC6XE&Quantity.4=1&ASIN.5=B084Q16G8D&Quantity.5=1&ASIN.6=B0BX32CXP6&Quantity.6=1&ASIN.7=B0DDBDYZWN&Quantity.7=1&AssociateTag=lovi-care-web-routine07-22) [Buy Shiseido routine · S$256.58 · 74% fit](https://www.amazon.sg/gp/aws/cart/add.html?ASIN.1=B07Q2HNRTB&Quantity.1=1&ASIN.2=B09SBSPXTY&Quantity.2=1&ASIN.3=B007SAC6XE&Quantity.3=1&ASIN.4=B084Q16G8D&Quantity.4=1&ASIN.5=B0DDBDYZWN&Quantity.5=1&AssociateTag=lovi-care-web-routine07-22) [See multi-brand routine · 99% fit](https://lovi.care/skincare/sg/skin/dry-skin)

### Good Molecules vs Shiseido routines for oily skin

#### Good Molecules-focused routine

- Cleanser: [CeraVe Foaming Facial Cleanser](https://lovi.care/skincare/sg/p/cerave/foaming-facial-cleanser/for/oily-skin) — Superior fit — [S$30.40 at Amazon](https://www.amazon.sg/dp/B07RJ18VMF?tag=lovi-care-web-routine07-22&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- Hydrating Toner: [TROIAREUKE H+Cocktail Purifying Ampoule Toner](https://lovi.care/skincare/sg/p/troiareuke/h-cocktail-purifying-ampoule-toner/for/oily-skin) — Superior fit — [S$168.51 at Amazon](https://www.amazon.sg/dp/B00S7GMF02?tag=lovi-care-web-routine07-22&linkCode=osi&th=1&psc=1) — Morning · Once a week
- Moisturizer: [SKIN1004 Centella Cream](https://lovi.care/skincare/sg/p/skin1004/centella-cream/for/oily-skin) — Superior fit — [S$33.87 at Amazon](https://www.amazon.sg/dp/B0C8SBJD89?tag=lovi-care-web-routine07-22&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- SPF: [CeraVe AM Facial Moisturizing Lotion SPF 30](https://lovi.care/skincare/sg/p/cerave/am-facial-moisturizing-lotion-spf-30/for/oily-skin) — Superior fit — [S$28.72 at Amazon](https://www.amazon.sg/dp/B077TQR6ZW?tag=lovi-care-web-routine07-22&linkCode=osi&th=1&psc=1) — Morning
- Pre-Cleanser: [Shu Uemura Ultime8 Sublime Beauty Cleansing Oil](https://lovi.care/skincare/sg/p/shu-uemura/ultime8-sublime-beauty-cleansing-oil/for/oily-skin) — Superior fit — [S$70.21 at Amazon](https://www.amazon.sg/dp/B0DNJKPSB8?tag=lovi-care-web-routine07-22&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Cleansing Toner: [Medicube Zero Pore Pad 2.0](https://lovi.care/skincare/sg/p/medicube/zero-pore-pad-2-0/for/oily-skin) — Superior fit — [S$36.48 at Amazon](https://www.amazon.sg/dp/B0CV7RX6ML?tag=lovi-care-web-routine07-22&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Serum or Treatment: [Overnight Exfoliating Treatment](https://lovi.care/skincare/sg/p/good-molecules/overnight-exfoliating-treatment/for/oily-skin) — Superior fit — [S$43.99 at Amazon](https://www.amazon.sg/dp/B08TMDRF1L?tag=lovi-care-web-routine07-22&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Cleansing Mask: [HERBIVORE Botanicals Blue Tansy BHA and Enzyme Pore Refining Mask](https://lovi.care/skincare/sg/p/herbivore-botanicals/blue-tansy-bha-and-enzyme-pore-refining-mask/for/oily-skin) — Superior fit — [S$89.14 at Amazon](https://www.amazon.sg/dp/B015RRNQCY?tag=lovi-care-web-routine07-22&linkCode=osi&th=1&psc=1) — Once a week

#### Shiseido-focused routine

- Cleanser: [Deep Cleansing Foam](https://lovi.care/skincare/sg/p/shiseido/deep-cleansing-foam/for/oily-skin) — High fit — [S$52.06 at Amazon](https://www.amazon.sg/dp/B07HYQXNKF?tag=lovi-care-web-routine07-22&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- Hydrating Toner: [Eudermine Revitalizing Essence](https://lovi.care/skincare/sg/p/shiseido/eudermine-revitalizing-essence/for/oily-skin) — Average fit — [S$112.11 at YesStyle](https://www.yesstyle.com/en/shiseido-eudermine-revitalizing-essence-200ml/info.html/pid.1076117866?curr=SGD&rco=SG) — Morning · Once a week
- Moisturizer: [Essential Energy Hydrating Cream](https://lovi.care/skincare/sg/p/shiseido/essential-energy-hydrating-cream/for/oily-skin) — Average fit — [S$78.82 at Amazon](https://www.amazon.sg/dp/B09SBSPXTY?tag=lovi-care-web-routine07-22&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- SPF: [CeraVe AM Facial Moisturizing Lotion SPF 30](https://lovi.care/skincare/sg/p/cerave/am-facial-moisturizing-lotion-spf-30/for/oily-skin) — Superior fit — [S$28.72 at Amazon](https://www.amazon.sg/dp/B077TQR6ZW?tag=lovi-care-web-routine07-22&linkCode=osi&th=1&psc=1) — Morning
- Pre-Cleanser: [Shu Uemura Ultime8 Sublime Beauty Cleansing Oil](https://lovi.care/skincare/sg/p/shu-uemura/ultime8-sublime-beauty-cleansing-oil/for/oily-skin) — Superior fit — [S$70.21 at Amazon](https://www.amazon.sg/dp/B0DNJKPSB8?tag=lovi-care-web-routine07-22&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Cleansing Toner: [Medicube Zero Pore Pad 2.0](https://lovi.care/skincare/sg/p/medicube/zero-pore-pad-2-0/for/oily-skin) — Superior fit — [S$36.48 at Amazon](https://www.amazon.sg/dp/B0CV7RX6ML?tag=lovi-care-web-routine07-22&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Serum or Treatment: [Ultimune Power Infusing Concentrate](https://lovi.care/skincare/sg/p/shiseido/ultimune-power-infusing-concentrate/for/oily-skin) — Average fit — [S$9.25 at YesStyle](https://www.yesstyle.com/en/shiseido-ultimune-power-infusing-serum-10ml/info.html/pid.1129827910?curr=SGD&rco=SG) — Evening · Once a week
- Cleansing Mask: [HERBIVORE Botanicals Blue Tansy BHA and Enzyme Pore Refining Mask](https://lovi.care/skincare/sg/p/herbivore-botanicals/blue-tansy-bha-and-enzyme-pore-refining-mask/for/oily-skin) — Superior fit — [S$89.14 at Amazon](https://www.amazon.sg/dp/B015RRNQCY?tag=lovi-care-web-routine07-22&linkCode=osi&th=1&psc=1) — Once a week

[Buy Good Molecules routine · S$501.32 · 96% fit](https://www.amazon.sg/gp/aws/cart/add.html?ASIN.1=B07RJ18VMF&Quantity.1=1&ASIN.2=B00S7GMF02&Quantity.2=1&ASIN.3=B0C8SBJD89&Quantity.3=1&ASIN.4=B077TQR6ZW&Quantity.4=1&ASIN.5=B0DNJKPSB8&Quantity.5=1&ASIN.6=B0CV7RX6ML&Quantity.6=1&ASIN.7=B08TMDRF1L&Quantity.7=1&ASIN.8=B015RRNQCY&Quantity.8=1&AssociateTag=lovi-care-web-routine07-22) [Buy Shiseido routine · S$355.43 · 82% fit](https://www.amazon.sg/gp/aws/cart/add.html?ASIN.1=B07HYQXNKF&Quantity.1=1&ASIN.2=B09SBSPXTY&Quantity.2=1&ASIN.3=B077TQR6ZW&Quantity.3=1&ASIN.4=B0DNJKPSB8&Quantity.4=1&ASIN.5=B0CV7RX6ML&Quantity.5=1&ASIN.6=B015RRNQCY&Quantity.6=1&AssociateTag=lovi-care-web-routine07-22) [See multi-brand routine · 96% fit](https://lovi.care/skincare/sg/skin/oily-skin)

### Good Molecules vs Shiseido routines for combination skin

#### Good Molecules-focused routine

- Cleanser: [Fresh Soy Face Cleanser](https://lovi.care/skincare/sg/p/fresh/soy-face-cleanser/for/combination-skin) — Superior fit — [S$30.00 at Amazon](https://www.amazon.sg/dp/B0013522FC?tag=lovi-care-web-routine07-22&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- Hydrating Toner: [Whamisa Organic Flowers Toner Deep Rich](https://lovi.care/skincare/sg/p/whamisa/organic-flowers-toner-deep-rich/for/combination-skin) — Superior fit — [S$64.81 at Amazon](https://www.amazon.sg/dp/B01N7P9N8I?tag=lovi-care-web-routine07-22&linkCode=osi&th=1&psc=1) — Morning · Once a week
- SPF: [CeraVe AM Facial Moisturizing Lotion SPF 30](https://lovi.care/skincare/sg/p/cerave/am-facial-moisturizing-lotion-spf-30/for/combination-skin) — Superior fit — [S$28.72 at Amazon](https://www.amazon.sg/dp/B077TQR6ZW?tag=lovi-care-web-routine07-22&linkCode=osi&th=1&psc=1) — Morning
- Pre-Cleanser: [Shu Uemura Ultime8 Sublime Beauty Cleansing Oil](https://lovi.care/skincare/sg/p/shu-uemura/ultime8-sublime-beauty-cleansing-oil/for/combination-skin) — Superior fit — [S$70.21 at Amazon](https://www.amazon.sg/dp/B0DNJKPSB8?tag=lovi-care-web-routine07-22&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Cleansing Toner: [Medicube Zero Pore Pad 2.0](https://lovi.care/skincare/sg/p/medicube/zero-pore-pad-2-0/for/combination-skin) — Superior fit — [S$36.48 at Amazon](https://www.amazon.sg/dp/B0CV7RX6ML?tag=lovi-care-web-routine07-22&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Serum or Treatment: [Overnight Exfoliating Treatment](https://lovi.care/skincare/sg/p/good-molecules/overnight-exfoliating-treatment/for/combination-skin) — Superior fit — [S$43.99 at Amazon](https://www.amazon.sg/dp/B08TMDRF1L?tag=lovi-care-web-routine07-22&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Cleansing Mask: [HERBIVORE Botanicals Blue Tansy BHA and Enzyme Pore Refining Mask](https://lovi.care/skincare/sg/p/herbivore-botanicals/blue-tansy-bha-and-enzyme-pore-refining-mask/for/combination-skin) — Superior fit — [S$89.14 at Amazon](https://www.amazon.sg/dp/B015RRNQCY?tag=lovi-care-web-routine07-22&linkCode=osi&th=1&psc=1) — Once a week

#### Shiseido-focused routine

- Cleanser: [Deep Cleansing Foam](https://lovi.care/skincare/sg/p/shiseido/deep-cleansing-foam/for/combination-skin) — High fit — [S$52.06 at Amazon](https://www.amazon.sg/dp/B07HYQXNKF?tag=lovi-care-web-routine07-22&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- Hydrating Toner: [Eudermine Revitalizing Essence](https://lovi.care/skincare/sg/p/shiseido/eudermine-revitalizing-essence/for/combination-skin) — High fit — [S$112.11 at YesStyle](https://www.yesstyle.com/en/shiseido-eudermine-revitalizing-essence-200ml/info.html/pid.1076117866?curr=SGD&rco=SG) — Morning · Once a week
- Moisturizer: [Essential Energy Hydrating Cream](https://lovi.care/skincare/sg/p/shiseido/essential-energy-hydrating-cream/for/combination-skin) — Average fit — [S$78.82 at Amazon](https://www.amazon.sg/dp/B09SBSPXTY?tag=lovi-care-web-routine07-22&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- SPF: [CeraVe AM Facial Moisturizing Lotion SPF 30](https://lovi.care/skincare/sg/p/cerave/am-facial-moisturizing-lotion-spf-30/for/combination-skin) — Superior fit — [S$28.72 at Amazon](https://www.amazon.sg/dp/B077TQR6ZW?tag=lovi-care-web-routine07-22&linkCode=osi&th=1&psc=1) — Morning
- Pre-Cleanser: [Shu Uemura Ultime8 Sublime Beauty Cleansing Oil](https://lovi.care/skincare/sg/p/shu-uemura/ultime8-sublime-beauty-cleansing-oil/for/combination-skin) — Superior fit — [S$70.21 at Amazon](https://www.amazon.sg/dp/B0DNJKPSB8?tag=lovi-care-web-routine07-22&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Cleansing Toner: [Medicube Zero Pore Pad 2.0](https://lovi.care/skincare/sg/p/medicube/zero-pore-pad-2-0/for/combination-skin) — Superior fit — [S$36.48 at Amazon](https://www.amazon.sg/dp/B0CV7RX6ML?tag=lovi-care-web-routine07-22&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Serum or Treatment: [Ultimune Power Infusing Concentrate](https://lovi.care/skincare/sg/p/shiseido/ultimune-power-infusing-concentrate/for/combination-skin) — Average fit — [S$9.25 at YesStyle](https://www.yesstyle.com/en/shiseido-ultimune-power-infusing-serum-10ml/info.html/pid.1129827910?curr=SGD&rco=SG) — Evening · Once a week
- Cleansing Mask: [HERBIVORE Botanicals Blue Tansy BHA and Enzyme Pore Refining Mask](https://lovi.care/skincare/sg/p/herbivore-botanicals/blue-tansy-bha-and-enzyme-pore-refining-mask/for/combination-skin) — Superior fit — [S$89.14 at Amazon](https://www.amazon.sg/dp/B015RRNQCY?tag=lovi-care-web-routine07-22&linkCode=osi&th=1&psc=1) — Once a week

[Buy Good Molecules routine · S$363.35 · 97% fit](https://www.amazon.sg/gp/aws/cart/add.html?ASIN.1=B0013522FC&Quantity.1=1&ASIN.2=B01N7P9N8I&Quantity.2=1&ASIN.3=B077TQR6ZW&Quantity.3=1&ASIN.4=B0DNJKPSB8&Quantity.4=1&ASIN.5=B0CV7RX6ML&Quantity.5=1&ASIN.6=B08TMDRF1L&Quantity.6=1&ASIN.7=B015RRNQCY&Quantity.7=1&AssociateTag=lovi-care-web-routine07-22) [Buy Shiseido routine · S$355.43 · 82% fit](https://www.amazon.sg/gp/aws/cart/add.html?ASIN.1=B07HYQXNKF&Quantity.1=1&ASIN.2=B09SBSPXTY&Quantity.2=1&ASIN.3=B077TQR6ZW&Quantity.3=1&ASIN.4=B0DNJKPSB8&Quantity.4=1&ASIN.5=B0CV7RX6ML&Quantity.5=1&ASIN.6=B015RRNQCY&Quantity.6=1&AssociateTag=lovi-care-web-routine07-22) [See multi-brand routine · 97% fit](https://lovi.care/skincare/sg/skin/combination-skin)

## Questions and answers

### Good Molecules or Shiseido: which is better?

Good Molecules offers better value with more affordable prices and fragrance-free formulas, while Shiseido provides more luxurious textures and deep hydration. For dry skin routines, Lovi rates Good Molecules as Superior and Shiseido as Average.

### What is the difference between Good Molecules and Shiseido?

Good Molecules offers a more affordable price point and great value, while Shiseido provides deep hydration and luxurious textures. Good Molecules also stands out for its fragrance-free formulas, as every product on this page lists no fragrance, whereas 15 of Shiseido's 20 products contain fragrance.

### Good Molecules or Shiseido for dry skin?

Good Molecules is the better choice for dry skin, as Lovi rates its routine fit as Superior compared to Shiseido's Average. Good Molecules offers deeply hydrating and affordable moisturizers and [serums](https://lovi.care/skincare/sg/ingredients/serum) that help nourish dry skin effectively.

### Good Molecules or Shiseido: which cleanser is better?

Good Molecules is the better choice for cleansers because Lovi rates its Hydrating Facial Cleansing Gel as High for dry and sensitive skin, whereas Shiseido cleansers range from Low to Caution for those skin types.

### Which is more affordable, Good Molecules or Shiseido?

Good Molecules is more affordable, as reviewers mention it offers affordable and great value serums and moisturizers. In contrast, reviewers note that Shiseido has a high price point.

### Which brand has products that are entirely free of fragrance according to the ingredients lists?

Good Molecules has products that are entirely free of fragrance on this page, as every single item lists no fragrance in its ingredients.

### How do the founding years and countries of origin compare between Good Molecules and Shiseido?

Good Molecules was founded in the United States in 2019, whereas Shiseido is a much older brand founded in Japan in 1872.

### Which brand performs better for providing deep hydration and moisture according to review themes?

Shiseido performs better for providing deep hydration and moisture according to the review themes.

### Good Molecules or Shiseido for oily skin?

Good Molecules is a Superior fit for oily skin, whereas Shiseido is a High fit. Reviewers note that Good Molecules offers affordable and great value serums, while Shiseido products often feature strong fragrances.

### Good Molecules or Shiseido: which moisturizer is better?

Good Molecules is better for moisturizers because it offers affordable and hydrating options with zero fragrance across its products. Reviewers highlight Good Molecules for its affordable price and great value, whereas Shiseido is often noted for a high price point and strong fragrance complaints.

### Good Molecules or Shiseido for sensitive skin?

Good Molecules is a better fit for sensitive skin, offering a Superior routine fit compared to Shiseido's High fit on this page. Good Molecules also has the advantage of listing no fragrance across its products.

### Good Molecules or Shiseido: which sunscreen is better?

Good Molecules offers a superior fit for dry sensitive skin, dry skin, sensitive skin, skin with dark spots, and mature skin with its Sheer Mineral Sunscreen [SPF 30](https://lovi.care/skincare/sg/ingredients/spf-30). In contrast, Shiseido features options like the Benefiance Wrinkle Smoothing Day Cream and Essential Energy Hydrating Day Cream, though reviewers frequently mention a strong fragrance.

### Good Molecules or Shiseido for acne-prone skin?

Good Molecules has a Superior routine fit for acne-prone skin, while Shiseido has a High routine fit. Reviewers mention that Good Molecules offers very gentle serums, though some note occasional breakouts.

## Research behind their key ingredients

- [Vitamin A antagonizes decreased cell growth and elevated collagen-degrading matrix metalloproteinases and stimulates collagen accumulation in naturally aged human skin](https://pubmed.ncbi.nlm.nih.gov/10692106/) Retinol · The Journal of Investigative Dermatology, 2000
- [The effect of niacinamide on reducing cutaneous pigmentation and suppression of melanosome transfer](https://pubmed.ncbi.nlm.nih.gov/12100180/) Niacinamide · The British Journal of Dermatology, 2002
- [Mechanistic Basis and Clinical Evidence for the Applications of Nicotinamide (Niacinamide) to Control Skin Aging and Pigmentation](https://pubmed.ncbi.nlm.nih.gov/34439563/) Niacinamide · Antioxidants, 2021
- [Benefits of topical hyaluronic acid for skin quality and signs of skin aging: From literature review to clinical evidence](https://pubmed.ncbi.nlm.nih.gov/36200921/) Sodium hyaluronate · Dermatologic Therapy, 2022
- [Topical use of dexpanthenol in skin disorders](https://pubmed.ncbi.nlm.nih.gov/12113650/) Panthenol · American Journal of Clinical Dermatology, 2002
- [Caffeine's mechanisms of action and its cosmetic use](https://pubmed.ncbi.nlm.nih.gov/23075568/) Caffeine · Skin Pharmacology and Physiology, 2013
- [Improvement of naturally aged skin with vitamin A (retinol)](https://pubmed.ncbi.nlm.nih.gov/17515510/) Retinol · Archives of Dermatology, 2007
- [Peroxidated squalene induces the production of inflammatory mediators in HaCaT keratinocytes: a possible role in acne vulgaris](https://pubmed.ncbi.nlm.nih.gov/16778793/) Squalane · The Journal of Investigative Dermatology, 2006
- [Anti-aging and brightening effects of a topical treatment containing vitamin C, vitamin E, and raspberry leaf cell culture extract: A split-face, randomized controlled trial](https://pubmed.ncbi.nlm.nih.gov/31975502/) Tocopherol · Journal of Cosmetic Dermatology, 2020
- [Molecular basis of retinol anti-ageing properties in naturally aged human skin in vivo](https://pubmed.ncbi.nlm.nih.gov/27261203/) Retinol · International Journal of Cosmetic Science, 2017
- [Psychophysical study of the effects of topical application of menthol in healthy volunteers](https://pubmed.ncbi.nlm.nih.gov/16527405/) Menthol · Pain, 2006
- [Prospective, randomized, double-blind assessment of topical bakuchiol and retinol for facial photoageing](https://pubmed.ncbi.nlm.nih.gov/29947134/) Bakuchiol · The British Journal of Dermatology, 2019
- [Evaluation of efficacy and tolerance of a nighttime topical antioxidant containing resveratrol, baicalin, and vitamin e for treatment of mild to moderately photodamaged skin](https://pubmed.ncbi.nlm.nih.gov/25607790/) Scutellaria baicalensis root extract · Journal of Drugs in Dermatology, 2014
- [Ethanol extracts of Sanguisorba officinalis L. suppress TNF-α/IFN-γ-induced pro-inflammatory chemokine production in HaCaT cells](https://pubmed.ncbi.nlm.nih.gov/26655409/) Sanguisorba officinalis root extract · Phytomedicine, 2015
- [Skin barrier disruption by sodium lauryl sulfate-exposure alters the expressions of involucrin, transglutaminase 1, profilaggrin, and kallikreins during the repair phase in human skin in vivo](https://pubmed.ncbi.nlm.nih.gov/18007579/) Sodium lauryl sulfate · The Journal of Investigative Dermatology, 2008
- [Panax ginseng induces human Type I collagen synthesis through activation of Smad signaling](https://pubmed.ncbi.nlm.nih.gov/16890388/) Panax ginseng root extract · Journal of Ethnopharmacology, 2007
- [The effects of a topical gel containing chitosan, 0,2% chlorhexidine, allantoin and despanthenol on the wound healing process subsequent to impacted lower third molar extraction](https://pubmed.ncbi.nlm.nih.gov/27475700/) Allantoin · Medicina Oral, Patologia Oral Y Cirugia Bucal, 2016
- [Effect of fermentation time on the content of bioactive compounds with cosmetic and dermatological properties in Kombucha Yerba Mate extracts](https://pubmed.ncbi.nlm.nih.gov/34552134/) Ilex paraguariensis leaf extract · Scientific Reports, 2021
- [Vitamin C-squalene bioconjugate promotes epidermal thickening and collagen production in human skin](https://pubmed.ncbi.nlm.nih.gov/33037252/) Squalane · Scientific Reports, 2020
- [Treatment of acne with a combination of propolis, tea tree oil, and Aloe vera compared to erythromycin cream: two double-blind investigations](https://pubmed.ncbi.nlm.nih.gov/30588129/) Aloe barbadensis leaf juice · Clinical Pharmacology, 2018
- [Anti-acne vulgaris effects of chlorogenic acid by anti-inflammatory activity and lipogenesis inhibition](https://pubmed.ncbi.nlm.nih.gov/33433016/) Ilex paraguariensis leaf extract · Experimental Dermatology, 2021
- [Effect of a topical antioxidant serum containing vitamin C, vitamin E, and ferulic acid after Q-switched 1064-nm Nd:YAG laser for treatment of environment-induced skin pigmentation](https://pubmed.ncbi.nlm.nih.gov/32052907/) Ascorbic acid, Ascorbic acid powder · Journal of Cosmetic Dermatology, 2020
- [A double-blind, placebo-controlled randomized trial of Serratulae quinquefoliae folium, a new source of β-arbutin, in selected skin hyperpigmentations](https://pubmed.ncbi.nlm.nih.gov/26119285/) Arbutin · Journal of Cosmetic Dermatology, 2015
- [Licochalcone A activates Nrf2 in vitro and contributes to licorice extract-induced lowered cutaneous oxidative stress in vivo](https://pubmed.ncbi.nlm.nih.gov/25381913/) Licorice root extract · Experimental Dermatology, 2015
- [Green tea extract reduces induction of p53 and apoptosis in UVB-irradiated human skin independent of transcriptional controls](https://pubmed.ncbi.nlm.nih.gov/18631247/) Camellia sinensis leaf extract · Experimental Dermatology, 2009
- [A review of topical high-concentration L-menthol as a translational model of cold allodynia and hyperalgesia](https://pubmed.ncbi.nlm.nih.gov/23963768/) Menthol · European Journal of Pain, 2014
- [Design, preparation, and evaluation of liposomal gel formulations for treatment of acne: in vitro and in vivo studies](https://pubmed.ncbi.nlm.nih.gov/30442066/) Lauric acid · Drug Development and Industrial Pharmacy, 2019
- [The 24-hour skin hydration and barrier function effects of a hyaluronic 1%, glycerin 5%, and Centella asiatica stem cells extract moisturizing fluid: an intra-subject, randomized, assessor-blinded study](https://pubmed.ncbi.nlm.nih.gov/28860834/) Glycerin · Clinical, Cosmetic and Investigational Dermatology, 2017
- [Randomized controlled study for the anti-aging effect of human adipocyte-derived mesenchymal stem cell media combined with niacinamide after laser therapy](https://pubmed.ncbi.nlm.nih.gov/33103316/) Niacinamide · Journal of Cosmetic Dermatology, 2021
- [Reduction in the appearance of facial hyperpigmentation by topical N-acetyl glucosamine](https://pubmed.ncbi.nlm.nih.gov/17348991/) Acetyl glucosamine · Journal of Cosmetic Dermatology, 2007
- [In vitro antioxidant, collagenase inhibition, and in vivo anti-wrinkle effects of combined formulation containing Punica granatum, Ginkgo biloba, Ficus carica, and Morus alba fruits extract](https://pubmed.ncbi.nlm.nih.gov/26203268/) Ginkgo biloba leaf extract · Clinical, Cosmetic and Investigational Dermatology, 2015
- [The anti-wrinkle efficacy of argireline, a synthetic hexapeptide, in Chinese subjects: a randomized, placebo-controlled study](https://pubmed.ncbi.nlm.nih.gov/23417317/) Acetyl hexapeptide-8 · American Journal of Clinical Dermatology, 2013
- [A new topical panthenol-containing emollient: Results from two randomized controlled studies assessing its skin moisturization and barrier restoration potential, and the effect on skin microflora](https://pubmed.ncbi.nlm.nih.gov/27425824/) Panthenol · The Journal of Dermatological Treatment, 2017
- [A Double-Blinded, Randomized, Vehicle-Controlled Study of the Efficacy of Moisturizer Containing Licochalcone A, Decanediol, L-Carnitine, and Salicylic Acid for Prevention of Acne Relapse in Asian Population](https://pubmed.ncbi.nlm.nih.gov/33150170/) Salicylic acid · BioMed Research International, 2020
- [Senomorphic activity of a combination of niacinamide and hyaluronic acid: correlation with clinical improvement of skin aging](https://pubmed.ncbi.nlm.nih.gov/39009698/) Niacinamide · Scientific Reports, 2024
- [Comparative study of efficacy and safety of 45% mandelic acid versus 30% salicylic acid peels in mild-to-moderate acne vulgaris](https://pubmed.ncbi.nlm.nih.gov/31553119/) Mandelic acid · Journal of Cosmetic Dermatology, 2020
- [Another Reason for Using Caffeine in Dermocosmetics: Sunscreen Adjuvant](https://pubmed.ncbi.nlm.nih.gov/31130869/) Caffeine · Frontiers in Physiology, 2019
- [The efficacy of glycolic acid, salicylic acid, gluconolactone, and licochalcone A combined with 0.1% adapalene vs adapalene monotherapy in mild-to-moderate acne vulgaris: a double-blinded within-person comparative study](https://pubmed.ncbi.nlm.nih.gov/30858720/) Glycolic acid · Clinical, Cosmetic and Investigational Dermatology, 2019
- [Efficacy of a topical gel containing chitosan, chlorhexidine, allantoin and dexpanthenol for pain and inflammation control after third molar surgery: A randomized and placebo-controlled clinical trial](https://pubmed.ncbi.nlm.nih.gov/32683390/) Allantoin · Medicina Oral, Patologia Oral Y Cirugia Bucal, 2020
- [Clinical evidence of the efficacy and safety of a new 3-in-1 anti-aging topical night serum-in-oil containing melatonin, bakuchiol, and ascorbyl tetraisopalmitate: 103 females treated from 28 to 84 days](https://pubmed.ncbi.nlm.nih.gov/30924254/) Tetrahexyldecyl ascorbate · Journal of Cosmetic Dermatology, 2019
- [Sunscreens and Cosmetic Formulations Containing Ascorbyl Tetraisopalmitate and Rice Peptides for the Improvement of Skin Photoaging: A Double-blind, Randomized Placebo-controlled Clinical Study](https://pubmed.ncbi.nlm.nih.gov/33529350/) Tetrahexyldecyl ascorbate · Photochemistry and Photobiology, 2021
- [High molecular compounds (polysaccharides and proanthocyanidins) from Hamamelis virginiana bark: influence on human skin keratinocyte proliferation and differentiation and influence on irritated skin](https://pubmed.ncbi.nlm.nih.gov/11684194/) Witch hazel leaf extract · Phytochemistry, 2001
- [Daily Fluctuation of Facial Pore Area, Roughness and Redness among Young Japanese Women; Beneficial Effects of Galactomyces Ferment Filtrate Containing Antioxidative Skin Care Formula](https://pubmed.ncbi.nlm.nih.gov/34198790/) Saccharomyces ferment filtrate · Journal of Clinical Medicine, 2021
- [Anti-Wrinkle Efficacy of Cross-Linked Hyaluronic Acid-Based Microneedle Patch with Acetyl Hexapeptide-8 and Epidermal Growth Factor on Korean Skin](https://pubmed.ncbi.nlm.nih.gov/33911590/) Acetyl hexapeptide-8 · Annals of Dermatology, 2019
- [Efficacy of a multitargeted, salicylic acid-based dermocosmetic cream compared to benzoyl peroxide 5% in Acne vulgaris: Results from a randomized study](https://pubmed.ncbi.nlm.nih.gov/37941097/) Salicylic acid · Journal of Cosmetic Dermatology, 2024
- [Biomimetic hyaluronic acid-stabilized zinc oxide nanoparticles in acne treatment: A preclinical and clinical approach](https://pubmed.ncbi.nlm.nih.gov/40254135/) Zinc oxide · Journal of Controlled Release, 2025
- [Preparation and evaluation of anti-wrinkle cream containing saffron extract and avocado oil](https://pubmed.ncbi.nlm.nih.gov/31957954/) Avocado oil · Journal of Cosmetic Dermatology, 2020
- [Evaluation of dermal extracellular matrix and epidermal-dermal junction modifications using matrix-assisted laser desorption/ionization mass spectrometric imaging, in vivo reflectance confocal microscopy, echography, and histology: effect of age and peptide applications](https://pubmed.ncbi.nlm.nih.gov/25817264/) Palmitoyl tetrapeptide-7, Palmitoyl tripeptide-1 · Journal of Cosmetic Dermatology, 2015
- [Changes in Skin Barrier Function after Repeated Exposition to Phospholipid-Based Surfactants and Sodium Dodecyl Sulfate In Vivo and Corneocyte Surface Analysis by Atomic Force Microscopy](https://pubmed.ncbi.nlm.nih.gov/33804924/) Sodium lauryl sulfate · Pharmaceutics, 2021
- [A Salicylic Acid-Based Dermocosmetic is Effective as an Adjunct to Benzoyl Peroxide for Mild to Moderate Acne and as Monotherapy in Maintenance Post Benzoyl Peroxide](https://pubmed.ncbi.nlm.nih.gov/38051857/) Salicylic acid · Journal of Drugs in Dermatology, 2023
- [Chemical peels for acne vulgaris: a systematic review of randomised controlled trials](https://pubmed.ncbi.nlm.nih.gov/29705755/) Mandelic acid · BMJ Open, 2018
- [Antioxidant-based topical formulations influence on the inflammatory response of Japanese skin: A clinical study using non-invasive techniques](https://pubmed.ncbi.nlm.nih.gov/28385617/) Tetrahexyldecyl ascorbate · European Journal of Pharmaceutics and Biopharmaceutics, 2017
- [Botulinum toxin injection as a single or combined treatment with non-cross-linked high molecular weight and low molecular weight hyaluronic acid gel for neck rejuvenation: A randomized clinical trial](https://pubmed.ncbi.nlm.nih.gov/35775872/) Hydrolyzed hyaluronic acid · Dermatologic Therapy, 2022
- [Effects of 1,3-propanediol associated, or not, with butylene glycol and/or glycerol on skin hydration and skin barrier function](https://pubmed.ncbi.nlm.nih.gov/37699769/) Propanediol · International Journal of Cosmetic Science, 2024
- [Challenging the safety and efficacy of topically applied chlorogenic acid, apigenin, kaempferol, and naringenin by HET-CAM, HPLC-TBARS-EVSC, and laser Doppler flowmetry](https://pubmed.ncbi.nlm.nih.gov/38831914/) Ilex paraguariensis extract · Frontiers in Chemistry, 2024
- [Topical application of jojoba (Simmondsia chinensis L.) wax enhances the synthesis of pro-collagen III and hyaluronic acid and reduces inflammation in the ex-vivo human skin organ culture model](https://pubmed.ncbi.nlm.nih.gov/38344180/) Jojoba seed oil · Frontiers in Pharmacology, 2024
- [Evaluating the Safety and Efficacy of a Topical Formulation Containing Epidermal Growth Factor, Tranexamic Acid, Vitamin C, Arbutin, Niacinamide and Other Ingredients as Hydroquinone 4% Alternatives to Improve Hyperpigmentation: A Prospective, Randomized, Controlled Split Face Study](https://pubmed.ncbi.nlm.nih.gov/33022197/) Arbutin · Journal of Cosmetic Science, 2020
- [A novel model of inflammatory pain in human skin involving topical application of sodium lauryl sulfate](https://pubmed.ncbi.nlm.nih.gov/20358390/) Sodium lauryl sulfate · Inflammation Research, 2010
- [Subclinical, non-erythematous irritation with an open assay model (washing): sodium lauryl sulfate (SLS) versus sodium laureth sulfate (SLES)](https://pubmed.ncbi.nlm.nih.gov/11278060/) Sodium laureth sulfate · Food and Chemical Toxicology, 2001
- [Antiacne and antiblotch activities of a formulated combination of Aloe barbadensis leaf powder, Garcinia mangostana peel extract, and Camellia sinensis leaf extract](https://pubmed.ncbi.nlm.nih.gov/31239743/) Camellia sinensis leaf extract · Clinical, Cosmetic and Investigational Dermatology, 2019
- [The efficacy study of the combination of tripeptide-10-citrulline and acetyl hexapeptide-3. A prospective, randomized controlled study](https://pubmed.ncbi.nlm.nih.gov/28150423/) Acetyl hexapeptide-8 · Journal of Cosmetic Dermatology, 2017
- [Whitening effect of alpha-bisabolol in Asian women subjects](https://pubmed.ncbi.nlm.nih.gov/20642768/) Bisabolol · International Journal of Cosmetic Science, 2010
- ['All-natural' anti-wrinkle emulsion serum with Acmella oleracea extract: A design of experiments (DoE) formulation approach, rheology and in vivo skin performance/efficacy evaluation](https://pubmed.ncbi.nlm.nih.gov/34297422/) Acmella oleracea extract · International Journal of Cosmetic Science, 2021
- [Effect of a botanical cleansing lotion on skin sebum and erythema of the face: A randomized controlled blinded half-side comparison](https://pubmed.ncbi.nlm.nih.gov/30022595/) Willow bark extract · Journal of Cosmetic Dermatology, 2019
- [Anti-Inflammatory Effect of a Novel Topical Herbal Composition (VEL-091604) Consisting of Gentian Root, Licorice Root and Willow Bark Extract](https://pubmed.ncbi.nlm.nih.gov/30690691/) Willow bark extract · Planta Medica, 2019
- [In vivo and in vitro evaluation of octyl methoxycinnamate liposomes](https://pubmed.ncbi.nlm.nih.gov/24376350/) Ethylhexyl methoxycinnamate · International Journal of Nanomedicine, 2013
- [A retrospective assessment and comparison of the effectiveness of benzoyl peroxide; the combination of topical niacinamide, gallic acid, and lauric acid; and the combination of benzoyl peroxide and erythromycin in acne vulgaris](https://pubmed.ncbi.nlm.nih.gov/32390309/) Lauric acid · Dermatologic Therapy, 2020
- [Synergetic Effects of Aloe Vera Extract with Trimethylglycine for Targeted Aquaporin 3 Regulation and Long-Term Skin Hydration](https://pubmed.ncbi.nlm.nih.gov/38611819/) Betaine · Molecules, 2024
- [Clinical Development and Evaluation of a Multi-Component Dissolving Microneedle Patch for Skin Pigmentation Disorders](https://pubmed.ncbi.nlm.nih.gov/37571190/) 2-o-ethyl ascorbic acid · Polymers, 2023
- [Squalane as a Promising Agent Protecting UV-Induced Inhibition of Collagen Biosynthesis and Wound Healing in Human Dermal Fibroblast](https://pubmed.ncbi.nlm.nih.gov/40363772/) Squalane · Molecules, 2025
- [Microbicidal activity of tripotassium phosphate and fatty acids toward spoilage and pathogenic bacteria associated with poultry](https://pubmed.ncbi.nlm.nih.gov/16013388/) Myristic acid · Journal of Food Protection, 2005
- [Synergistic approach for acne vulgaris treatment using glycerosomes loaded with lincomycin and lauric acid: Formulation, in silico, in vitro, LC-MS/MS skin deposition assay and in vivo evaluation](https://pubmed.ncbi.nlm.nih.gov/37805147/) Lauric acid · International Journal of Pharmaceutics, 2023
- [New topical tranexamic acid derivative for the improvement of hyperpigmentation and inflammation in the sun-damaged skin](https://pubmed.ncbi.nlm.nih.gov/32588531/) Cetyl tranexamate mesylate · Journal of Cosmetic Dermatology, 2021
- [Formulation of Ascorbic Acid and Betaine-based Therapeutic Deep Eutectic System for Enhanced Transdermal Delivery of Ascorbic Acid](https://pubmed.ncbi.nlm.nih.gov/38794349/) Betaine · Pharmaceutics, 2024
- [Fabrication of polyvinyl pyrrolidone-K90/Eudragit RL100-based dissolving microneedle patches loaded with alpha-arbutin and resveratrol for skin depigmentation](https://pubmed.ncbi.nlm.nih.gov/37183632/) Arbutin · Biomaterials Science, 2023
- [Treatment of mild to moderate acne with a fixed combination of hydroxypinacolone retinoate, retinol glycospheres and papain glycospheres](https://pubmed.ncbi.nlm.nih.gov/25876142/) Papain · Giornale Italiano Di Dermatologia E Venereologia, 2015
- [Randomized prospective study of low-dose isotretinoin alone and combination with salicylic acid and mandelic peel against acne tarda](https://pubmed.ncbi.nlm.nih.gov/35388606/) Mandelic acid · Journal of Cosmetic Dermatology, 2022
- [Effect of hydroxypropyl-β-cyclodextrin in fluid and semi-solid submicron emulsions on physiological skin parameters during regular in vivo application](https://pubmed.ncbi.nlm.nih.gov/33236374/) Cyclodextrin · International Journal of Cosmetic Science, 2021
- [The use of different concentrations of betaine as a reducing irritation agent in soaps monitored visually and non-invasively](https://pubmed.ncbi.nlm.nih.gov/12535284/) Betaine · Skin Research and Technology, 2003
- [Influence of vitamin E acetate on stratum corneum hydration](https://pubmed.ncbi.nlm.nih.gov/9706379/) Tocopheryl acetate · Arzneimittel-Forschung, 1998
- [A randomized controlled trial to compare the effectiveness and safety of adsorbent lotion containing tapioca starch, spent grain wax, Butyrospermum parkii extract, argania spinosa kernel oil, aloe barbadensis, rosehip oil, and allantoin with a low-potency topical corticosteroid in the treatment of intertrigo](https://pubmed.ncbi.nlm.nih.gov/33811776/) Shea butter · Journal of Cosmetic Dermatology, 2022
- [Topical Zinc Oxide Nanoparticle Formulations for Acne Vulgaris: A Systematic Review of Pre-Clinical and Early-Phase Clinical Evidence](https://pubmed.ncbi.nlm.nih.gov/41007718/) Zinc oxide · Biomedicines, 2025
- [Anatomical site differences of sodium lauryl sulfate-induced irritation: randomized controlled trial](https://pubmed.ncbi.nlm.nih.gov/30637727/) Sodium lauryl sulfate · The British Journal of Dermatology, 2019
- [A controlled, three-part trial to investigate the barrier function and skin hydration properties of six skin protectants](https://pubmed.ncbi.nlm.nih.gov/16439809/) Dimethicone · Ostomy/wound Management, 2005
- [Skin recovery by Lavandula angustifolia leaf callus extract: Redox control of Nrf2 signaling](https://pubmed.ncbi.nlm.nih.gov/40345503/) Lavandula angustifolia oil lavender oil · Free Radical Biology & Medicine, 2025
- [Efficacy and Tolerability of Stable Hybrid Cooperative Complexes of High- and Low-Molecular Weight Hyaluronic Acid in Asian Patients: An Open-Label Study](https://pubmed.ncbi.nlm.nih.gov/40921777/) Hydrolyzed hyaluronic acid · Aesthetic Plastic Surgery, 2026
- [Propanediol (and) Caprylic Acid (and) Xylitol as a New Single Topical Active Ingredient against Acne: In Vitro and In Vivo Efficacy Assays](https://pubmed.ncbi.nlm.nih.gov/34771112/) Propanediol · Molecules, 2021
- [Enhanced Fluctuations in Facial Pore Size, Redness, and TEWL Caused by Mask Usage Are Normalized by the Application of a Moisturizer](https://pubmed.ncbi.nlm.nih.gov/35456214/) Saccharomyces ferment filtrate · Journal of Clinical Medicine, 2022
- [Evaluation of the Efficacy and Safety of a Panthenol-Enriched Mask for Skin Barrier Recovery After Facial Laser Treatment: Results of a Double-Blind Randomized Controlled Study](https://pubmed.ncbi.nlm.nih.gov/40613435/) Panthenol · Journal of Cosmetic Dermatology, 2025
- [The anti wrinkle efficacy of synthetic hexapeptide (Argireline) in Chinese Subjects](https://pubmed.ncbi.nlm.nih.gov/23607739/) Acetyl hexapeptide-8 · Journal of Cosmetic and Laser Therapy, 2013
- [Moisturizing Effects of Diglycerol Combined with Glycerol on Human Stratum Corneum](https://pubmed.ncbi.nlm.nih.gov/27430380/) Diglycerin · Journal of Oleo Science, 2016
- [Antioxidant and membrane-protective effects of the 3-O-ethyl ascorbic acid-cannabigerol system on UVB-irradiated human keratinocytes](https://pubmed.ncbi.nlm.nih.gov/39778604/) 2-o-ethyl ascorbic acid · Free Radical Biology & Medicine, 2025
- [Ginkgo biloba leaves extract's cosmeceutical evaluation: a preliminary assessments on human volunteers towards achieving improved skin condition and rejuvenation](https://pubmed.ncbi.nlm.nih.gov/37074796/) Ginkgo biloba leaf extract · Drug Development and Industrial Pharmacy, 2023
- [Combining Topical and Oral Botanicals for Skin Redness, Pigmentation, Sleep, and Mood: A Randomized Controlled Study](https://pubmed.ncbi.nlm.nih.gov/36431167/) Theanine · Journal of Clinical Medicine, 2022
- [Nanocomplex of quaternized cyclodextrin grafted chitosan and hyaluronic acid for a skin delivery](https://pubmed.ncbi.nlm.nih.gov/36279763/) Hydrolyzed hyaluronic acid · Colloids and Surfaces. B, Biointerfaces, 2022
- [Preliminary safety and in vivo efficacy of Acmella oleracea extract-loaded glycolipid emulsion serum-Effects on ocular irritation, dermal absorption, and facial skin biophysical and microrelief properties](https://pubmed.ncbi.nlm.nih.gov/39617635/) Acmella oleracea extract · International Journal of Cosmetic Science, 2025
- [Taurine and Polyphenol Complex Repaired Epidermal Keratinocyte Wounds by Regulating IL8 and TIMP2 Expression](https://pubmed.ncbi.nlm.nih.gov/39194729/) Ilex paraguariensis leaf extract · Current Issues in Molecular Biology, 2024
- [Nanostructured Lipid Carrier Based Gel Containing α-Tocopherol and α-Tocopheryl Acetate for Synergistic Cutaneous Antiaging Efficacy](https://pubmed.ncbi.nlm.nih.gov/41309687/) Tocopheryl acetate · Scientific Reports, 2025
- [Thermostable hyaluronic acid-based dissolving microneedles with high-loading capacity: design, optimization, and transdermal delivery of anti-aging ingredients](https://pubmed.ncbi.nlm.nih.gov/41628877/) 2-o-ethyl ascorbic acid · International Journal of Biological Macromolecules, 2026
- [Prospective randomized double-blind comparative study of topical acetyl zingerone with tetrahexyldecyl ascorbate versus tetrahexyldecyl ascorbate alone on facial photoaging](https://pubmed.ncbi.nlm.nih.gov/38525606/) Tetrahexyldecyl ascorbate · Journal of Cosmetic Dermatology, 2024
- [Hippophae rhamnoides oil-in-water (O/W) emulsion improves barrier function in healthy human subjects](https://pubmed.ncbi.nlm.nih.gov/25362595/) Hippophae rhamnoides oil · Pakistan Journal of Pharmaceutical Sciences, 2014
- [Development and efficacy assessments of tea seed oil makeup remover](https://pubmed.ncbi.nlm.nih.gov/27988044/) Camellia oleifera seed oil · Annales Pharmaceutiques Francaises, 2017
- [Functional properties and skin care effects of sodium trehalose sulfate](https://pubmed.ncbi.nlm.nih.gov/38606717/) Trehalose · Skin Research and Technology, 2024
- [Transdermal Delivery of Baicalin Based on Bio-Vesicles and Its Efficacy in Antiaging of the Skin](https://pubmed.ncbi.nlm.nih.gov/39946269/) Scutellaria baicalensis root extract · Journal of Cosmetic Dermatology, 2025
- [Effect of an Emollient Emulsion Containing 15.0% of Caprylic/Capric Triglyceride on the Urocanic Acid of the Stratum Corneum](https://pubmed.ncbi.nlm.nih.gov/37109405/) Caprylic capric triglyceride · Life, 2023
- [Effect of isosecotanapartholide isolated from Artemisia princeps Pampanini on IL‑33 production and STAT‑1 activation in HaCaT keratinocytes](https://pubmed.ncbi.nlm.nih.gov/28447741/) Artemisia princeps leaf extract · Molecular Medicine Reports, 2017
- [Liposomal formulation of a vitamin C derivative: a promising strategy to increase skin permeability](https://pubmed.ncbi.nlm.nih.gov/39985147/) 2-o-ethyl ascorbic acid · Journal of Liposome Research, 2025
- [Pleiotropic effects of a Camellia sinensis leaf extract on in vitro and in vivo skin health characteristics](https://pubmed.ncbi.nlm.nih.gov/40391588/) Camellia sinensis leaf water · International Journal of Cosmetic Science, 2025
- [Effects of fermented tea seed oil on the skin lipid barrier and microbiome of sensitive skin](https://pubmed.ncbi.nlm.nih.gov/41319188/) Camellia oleifera seed oil · International Journal of Cosmetic Science, 2026
- [Safety assessment on comedogenicity of dermatological products containing d-alpha tocopheryl acetate in Asian subjects: A double-blind randomized controlled trial](https://pubmed.ncbi.nlm.nih.gov/34471722/) Tocopheryl acetate · Contemporary Clinical Trials Communications, 2021
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- [Facial disbiosis and UV filters](https://pubmed.ncbi.nlm.nih.gov/39499337/) Ethylhexyl methoxycinnamate, Octocrylene · Archives of Dermatological Research, 2024
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- [The Effectiveness of Galactomyces Ferment Filtrate, Dexpanthenol, and Centella Asiatica Combination Serum in the Treatment of Post-Acne Hyperpigmentation in Subjects with Skin of Color](https://pubmed.ncbi.nlm.nih.gov/33938432/) Saccharomyces ferment filtrate · Skinmed, 2021
- [Efficacy of anti-sebum moisturizing cream containing 2% l-carnitine and 5% epigallocatechin gallate in seborrhea: A randomized clinical trial](https://pubmed.ncbi.nlm.nih.gov/37194909/) Uji green tea extract · Journal of Cosmetic Dermatology, 2023
- [Efficacy and safety of combination cream of stimu-tex AS™ (spent grain wax, Argania Spinosa Kernel oil, Butyrospermum Parkii (shea butter) extract), and saccharide isomerate after fractional CO2 laser procedure: split-face, double blinded, randomized controlled trial](https://pubmed.ncbi.nlm.nih.gov/41134387/) Shea butter · Lasers in Medical Science, 2025
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- [Retrospective Review of Dermal Safety Studies of Organic Sunscreens](https://pubmed.ncbi.nlm.nih.gov/40911743/) Homosalate · Journal of Drugs in Dermatology, 2025

## The brands

- American skincare: [Good Molecules](https://lovi.care/skincare/sg/brands/good-molecules)
- Japanese skincare: [Shiseido](https://lovi.care/skincare/sg/brands/shiseido)

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## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this comparison: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/compare/good-molecules-vs-shiseido
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- Canada: https://lovi.care/skincare/ca/compare/good-molecules-vs-shiseido
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- Singapore: https://lovi.care/skincare/sg/compare/good-molecules-vs-shiseido (this page)
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- United Arab Emirates: https://lovi.care/skincare/ae/compare/good-molecules-vs-shiseido