# Estée Lauder vs Medik8

Page: https://lovi.care/skincare/sg/compare/estee-lauder-vs-medik8

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Singapore.

Estée Lauder and Medik8 are established skincare houses offering comprehensive ranges of [serums](https://lovi.care/skincare/sg/ingredients/serum), moisturizers, eye products, and cleansers built around key ingredients like [hyaluronic acid](https://lovi.care/skincare/sg/ingredients/hyaluronic-acid) and [glycerin](https://lovi.care/skincare/sg/ingredients/glycerin). The American brand suits mature skin and oily, acne-prone skin best, featuring standout options such as the Micro Essence Treatment Lotion, the DayWear Moisturizer, and the Futurist Peptide-Power Serum Primer. Meanwhile, the British brand addresses similar concerns with targeted formulations like the Surface Radiance Cleanse, Oxy-R Peptides, and Total Moisture Daily Facial Cream. While both brands utilize hyaluronic acid to lengthen toxin wrinkle effect duration, they differ in their heritage, ownership, and specific botanical and scientific compositions.

Estée Lauder is an American skincare brand founded in 1946 and owned by The Estée Lauder Companies Inc..

[en.wikipedia.org](https://en.wikipedia.org/wiki/Est%C3%A9e_Lauder_Companies) [elcompanies.com](https://www.elcompanies.com/en/who-we-are/our-heritage)

Medik8 is a British skincare brand founded in 2009 and owned by L'Oréal Groupe since 2025.

[loreal.com](https://www.loreal.com/en/press-release/group/l-oreal-groupe-to-acquire-a-majority-stake-in-medik8/) [medik8.com](https://www.medik8.com/pages/founders-story) [tracxn.com](https://tracxn.com/d/companies/medik8/__vqs3N9eL3EfvIq0IoeUPADts7CrlGbzm7kjy9M9QY8o)

This page compares some of the most popular Estée Lauder and Medik8 products; for every product of both brands, with a fit score for your own skin, [use the Lovi app](https://app.pora.ai/vqqJ/j1xj2b6o?af_sub2=compare&af_sub3=selection_note&af_sub4=pg84e4e680bd).

### Popular Estée Lauder vs Medik8 products

#### Medik8

- [Liquid Peptides](https://lovi.care/skincare/sg/p/medik8/liquid-peptides/for/oily-acne-prone-skin) — Average fit
- [CRYSTAL RETINAL 3](https://lovi.care/skincare/sg/p/medik8/crystal-retinal-3/for/mature-skin) — High fit
- [C-Tetra Serum](https://lovi.care/skincare/sg/p/medik8/c-tetra-serum/for/dry-sensitive-skin) — Average fit
- [Bakuchiol Peptides](https://lovi.care/skincare/sg/p/medik8/bakuchiol-peptides/for/dry-skin) — Superior fit
- [Crystal Retinal Ceramide Eye 3](https://lovi.care/skincare/sg/p/medik8/crystal-retinal-ceramide-eye-3/for/mature-skin) — High fit
- [Oxy-R Peptides](https://lovi.care/skincare/sg/p/medik8/oxy-r-peptides/for/mature-skin) — Superior fit
- [Total Moisture Daily Facial Cream](https://lovi.care/skincare/sg/p/medik8/total-moisture-daily-facial-cream/for/mature-skin) — High fit
- [Hydr8 B5 Intense](https://lovi.care/skincare/sg/p/medik8/hydr8-b5-intense/for/dry-skin) — Superior fit

#### Estée Lauder

- [Advanced Night Repair](https://lovi.care/skincare/sg/p/estee-lauder/advanced-night-repair/for/acne-prone-skin) — Average fit — [S$13.55 at YesStyle](https://www.yesstyle.com/en/estee-lauder-advanced-night-repair-synchronized-multi-recovery-complex/info.html/pid.1130730977?curr=SGD&rco=SG)
- [Revitalizing Supreme+](https://lovi.care/skincare/sg/p/estee-lauder/revitalizing-supreme/for/mature-skin) — Average fit — [S$158.73 at YesStyle](https://www.yesstyle.com/en/estee-lauder-revitalizing-supreme-youth-power-soft-milky-lotion-100ml/info.html/pid.1126107836?curr=SGD&rco=SG)
- [Micro Essence Treatment Lotion](https://lovi.care/skincare/sg/p/estee-lauder/micro-essence-treatment-lotion/for/oily-acne-prone-skin) — Superior fit
- [Re-Nutriv](https://lovi.care/skincare/sg/p/estee-lauder/re-nutriv/for/dry-skin) — Low fit
- [Perfectionist Pro](https://lovi.care/skincare/sg/p/estee-lauder/perfectionist-pro/for/mature-skin) — Average fit
- [Advanced Night Repair Eye Supercharged Gel-Creme](https://lovi.care/skincare/sg/p/estee-lauder/advanced-night-repair-eye-supercharged-gel-creme/for/mature-skin) — High fit
- [Advanced Night Cleansing Gelée](https://lovi.care/skincare/sg/p/estee-lauder/advanced-night-cleansing-gelee/for/acne-prone-skin) — High fit
- [DayWear Moisturizer](https://lovi.care/skincare/sg/p/estee-lauder/daywear-moisturizer/for/dry-sensitive-skin) — Superior fit

## People Say

Estée Lauder

Medik8

- Deep hydration and moisturization Mostly Mentioned Often Mentioned “skin drinks it up immediately — Estée Lauder Advanced Night Repair” “The formula is incredibly hydrating and leaves my skin feeling smooth. — Estée Lauder Re-Nutriv” “texture is dreamy — Estée Lauder Advanced Night Repair Eye Supercharged Gel-Creme” “Restores moisture — Medik8 Liquid Peptides”
- Skin texture improvement and smoothing Often Mentioned Mostly Mentioned “absorbed effortlessly — Medik8 Total Moisture Daily Facial Cream” “My skin was smoother, my skin texture felt more resurfaced. — Medik8 Sleep Glycolic” “Absorbs fast — Medik8 Liquid Peptides” “Absorbs quickly into the skin — Estée Lauder Revitalizing Supreme+”
- Gentle and non-drying formula Often Mentioned Mostly Mentioned “zero irritation or peeling — Medik8 CRYSTAL RETINAL 3” “only Vitamin C my sensitive skin can tolerate — Medik8 C-Tetra Serum” “Best retinol replacement — Medik8 Bakuchiol Peptides” “doesn't strip the skin — Estée Lauder Advanced Night Cleansing Gelée”
- Radiance, glow and brightening Sometimes Noted Often Mentioned “I wake up glowing. It adds back that youthful bloom that I've lost. — Medik8 Sleep Glycolic” “unlocked a serious glow — Medik8 C-Tetra Serum” “immediate glow — Medik8 Super C Ferulic” “gives me that glass skin look — Estée Lauder Advanced Night Repair”
- Effective cleansing and makeup removal Sometimes Noted Rarely Noted “removes all my makeup effortlessly — Estée Lauder Advanced Night Cleansing Gelée” “Melts away Double Wear foundation instantly — Estée Lauder Take It Away Makeup Remover Lotion” “Leaves my skin very clean — Estée Lauder Soft Clean Moisture Rich Foaming Cleanser” “pores feel cleaner — Medik8 Surface Radiance Cleanse”
- Pleasant scent Sometimes Noted Rarely Noted “pleasant cucumber fragrance — Estée Lauder DayWear Moisturizer” “Smells luxurious and expensive — Estée Lauder Revitalizing Supreme+” “Smells fresh and clean — Estée Lauder Take It Away Makeup Remover Lotion” “smell is gorgeous — Medik8 C-Tetra Serum”
- High price point Mostly Mentioned Often Mentioned “Expensive per bottle — Medik8 Liquid Peptides” “very expensive for amount — Medik8 CRYSTAL RETINAL 3” “hefty price tag — Medik8 C-Tetra Serum” “way too expensive for the size — Estée Lauder Advanced Night Repair”
- Lack of results or effectiveness Sometimes Noted Sometimes Noted “didn't notice any difference — Estée Lauder Advanced Night Repair” “just expensive water — Estée Lauder Micro Essence Treatment Lotion” “Not as effective as retinol — Medik8 Bakuchiol Peptides” “no difference — Medik8 Oxy-R Peptides”
- Packaging issues and bulky design Sometimes Noted Sometimes Noted “lid is hard to open — Estée Lauder Advanced Night Cleansing Gelée” “Please make a jar or refill that is not as big and heavy. — Estée Lauder Re-Nutriv” “Glass bottle breaks easily — Medik8 Liquid Peptides” “hard to get last bit — Medik8 CRYSTAL RETINAL 3”
- Scent and fragrance complaints Often Mentioned Rarely Noted “metallic scent — Medik8 Super C Ferulic” “Scent is too overpowering — Estée Lauder Revitalizing Supreme+”

## Questions and answers

### Estée Lauder or Medik8: which is better?

Medik8 tends to do better for skin texture improvement, gentle formulas, and brightening, while Estée Lauder stands out for deep hydration and effective cleansing. The products on this page help improve skin quality and hydration, supported by studies on [hyaluronic acid](https://lovi.care/skincare/sg/ingredients/hyaluronic-acid).

[Dermatologic Therapy, 2022](https://pubmed.ncbi.nlm.nih.gov/36200921/) [Journal of Pharmacy & Pharmaceutical Sciences, 2015](https://pubmed.ncbi.nlm.nih.gov/25877441/)

### What is the difference between Estée Lauder and Medik8?

Estée Lauder tends to do better for deep hydration and moisturization, whereas Medik8 performs better for skin texture improvement and smoothing as well as gentle and non-drying formulas. Both brands share high price points among their drawbacks.

### Estée Lauder or Medik8: which cleanser is better?

For cleansers, Estée Lauder provides effective cleansing and makeup removal, while Medik8 offers a gentle and non-drying formula that may help improve skin texture. In terms of Lovi fit levels on this page, Estée Lauder's Advanced Night Cleansing Gelée is High for acne-prone, mature, and combination skin, whereas Medik8's Surface Radiance Cleanse is Superior for acne-prone skin and skin with dark spots.

### Which is more affordable, Estée Lauder or Medik8?

Reviewers on this page indicate that both Estee Lauder and Medik8 have a high price point, so neither brand is more affordable.

### Which causes fewer breakouts, Estée Lauder or Medik8?

When it comes to breakout prevention, Medik8 focuses on formulas that reviewers frequently note as gentle and non-irritating, whereas Estée Lauder's products on this page are rated as having an Average fit for acne-prone skin.

### Between Estée Lauder and Medik8, which brand provides better deep hydration according to review themes?

According to the review themes on this page, Estée Lauder provides better deep hydration and moisturization than Medik8. Topical hyaluronic acid helps provide deep hydration to the skin.

[Dermatologic Therapy, 2022](https://pubmed.ncbi.nlm.nih.gov/36200921/)

### How do the fragrance options compare between the two brands?

Estee Lauder has 12 out of 14 products on this page listing no fragrance, while Medik8 has 11 out of 12 unfragranced options. Both brands keep most of their products on this page free of added scents.

### Which brand is better suited for improving skin texture and providing a brightening glow?

Medik8 does better for improving skin texture and providing a brightening glow. The products on this page help deliver smoother skin and visible brightening.

### Estée Lauder or Medik8: which moisturizer is better?

When comparing moisturizers, Estée Lauder is better for deep hydration, while Medik8 is often noted for improving skin texture and providing a gentle, non-irritating formula. Both brands feature high price points as a common drawback in the products on this page.

## Research behind their key ingredients

- [Hyaluronic acid and wound healing](https://pubmed.ncbi.nlm.nih.gov/25877441/) Sodium hyaluronate · Journal of Pharmacy & Pharmaceutical Sciences, 2015
- [The effect of niacinamide on reducing cutaneous pigmentation and suppression of melanosome transfer](https://pubmed.ncbi.nlm.nih.gov/12100180/) Niacinamide · The British Journal of Dermatology, 2002
- [Skin delivery of epigallocatechin-3-gallate (EGCG) and hyaluronic acid loaded nano-transfersomes for antioxidant and anti-aging effects in UV radiation induced skin damage](https://pubmed.ncbi.nlm.nih.gov/28155509/) Hyaluronic acid · Drug Delivery, 2017
- [Benefits of topical hyaluronic acid for skin quality and signs of skin aging: From literature review to clinical evidence](https://pubmed.ncbi.nlm.nih.gov/36200921/) Hyaluronic acid, Sodium hyaluronate · Dermatologic Therapy, 2022
- [Topical use of dexpanthenol in skin disorders](https://pubmed.ncbi.nlm.nih.gov/12113650/) Panthenol · American Journal of Clinical Dermatology, 2002
- [Peroxidated squalene induces the production of inflammatory mediators in HaCaT keratinocytes: a possible role in acne vulgaris](https://pubmed.ncbi.nlm.nih.gov/16778793/) Squalane · The Journal of Investigative Dermatology, 2006
- [Anti-aging and brightening effects of a topical treatment containing vitamin C, vitamin E, and raspberry leaf cell culture extract: A split-face, randomized controlled trial](https://pubmed.ncbi.nlm.nih.gov/31975502/) Tocopherol vitamin e, Tocopherol, Ascorbic acid · Journal of Cosmetic Dermatology, 2020
- [A topical antioxidant solution containing vitamins C and E stabilized by ferulic acid provides protection for human skin against damage caused by ultraviolet irradiation](https://pubmed.ncbi.nlm.nih.gov/18603326/) Ferulic acid · Journal of the American Academy of Dermatology, 2008
- [Protective effects of a topical antioxidant mixture containing vitamin C, ferulic acid, and phloretin against ultraviolet-induced photodamage in human skin](https://pubmed.ncbi.nlm.nih.gov/19146606/) Ferulic acid · Journal of Cosmetic Dermatology, 2008
- [Production and characterization of cosmetic nanoemulsions containing Opuntia ficus-indica (L.) mill extract as moisturizing agent](https://pubmed.ncbi.nlm.nih.gov/25648593/) Hydrolyzed opuntia ficus-indica flower extract · Molecules, 2015
- [Topical anti-inflammatory effects of isorhamnetin glycosides isolated from Opuntia ficus-indica](https://pubmed.ncbi.nlm.nih.gov/25821823/) Hydrolyzed opuntia ficus-indica flower extract · BioMed Research International, 2015
- [Prospective, randomized, double-blind assessment of topical bakuchiol and retinol for facial photoageing](https://pubmed.ncbi.nlm.nih.gov/29947134/) Bakuchiol · The British Journal of Dermatology, 2019
- [Chrysin protects epidermal keratinocytes from UVA- and UVB-induced damage](https://pubmed.ncbi.nlm.nih.gov/21699266/) Passiflora incarnata flower extract · Journal of Agricultural and Food Chemistry, 2011
- [Topical delivery of tetrahydrocurcumin lipid nanoparticles effectively inhibits skin inflammation: in vitro and in vivo study](https://pubmed.ncbi.nlm.nih.gov/29938544/) Tetrahydrodiferuloylmethane · Drug Development and Industrial Pharmacy, 2018
- [Vitamin C-squalene bioconjugate promotes epidermal thickening and collagen production in human skin](https://pubmed.ncbi.nlm.nih.gov/33037252/) Squalane · Scientific Reports, 2020
- [Treatment of acne with a combination of propolis, tea tree oil, and Aloe vera compared to erythromycin cream: two double-blind investigations](https://pubmed.ncbi.nlm.nih.gov/30588129/) Aloe barbadensis leaf juice · Clinical Pharmacology, 2018
- [Urea: a comprehensive review of the clinical literature](https://pubmed.ncbi.nlm.nih.gov/24314769/) Urea · Dermatology Online Journal, 2013
- [Effects of glyceryl glucoside on AQP3 expression, barrier function and hydration of human skin](https://pubmed.ncbi.nlm.nih.gov/22584263/) Glyceryl glucoside · Skin Pharmacology and Physiology, 2012
- [Antioxidant Opuntia ficus-indica Extract Activates AHR-NRF2 Signaling and Upregulates Filaggrin and Loricrin Expression in Human Keratinocytes](https://pubmed.ncbi.nlm.nih.gov/26061570/) Hydrolyzed opuntia ficus-indica flower extract · Journal of Medicinal Food, 2015
- [Effect of a topical antioxidant serum containing vitamin C, vitamin E, and ferulic acid after Q-switched 1064-nm Nd:YAG laser for treatment of environment-induced skin pigmentation](https://pubmed.ncbi.nlm.nih.gov/32052907/) Tocopherol vitamin e, Ferulic acid · Journal of Cosmetic Dermatology, 2020
- [Inhibitory effect of mulberroside A and its derivatives on melanogenesis induced by ultraviolet B irradiation](https://pubmed.ncbi.nlm.nih.gov/21946069/) Hydroxyresveratrol · Food and Chemical Toxicology, 2011
- [Green tea extract reduces induction of p53 and apoptosis in UVB-irradiated human skin independent of transcriptional controls](https://pubmed.ncbi.nlm.nih.gov/18631247/) Camellia sinensis leaf extract · Experimental Dermatology, 2009
- [Clinical, biometric and structural evaluation of the long-term effects of a topical treatment with ascorbic acid and madecassoside in photoaged human skin](https://pubmed.ncbi.nlm.nih.gov/18503551/) Centella asiatica leaf extract · Experimental Dermatology, 2008
- [Proliferation and In Vitro Wound Healing Effects of the Microniosomes Containing Narcissus tazetta L. Bulb Extract on Primary Human Fibroblasts (HDFs)](https://pubmed.ncbi.nlm.nih.gov/30209758/) Narcissus tazetta bulb extract · Daru, 2018
- [The 24-hour skin hydration and barrier function effects of a hyaluronic 1%, glycerin 5%, and Centella asiatica stem cells extract moisturizing fluid: an intra-subject, randomized, assessor-blinded study](https://pubmed.ncbi.nlm.nih.gov/28860834/) Glycerin · Clinical, Cosmetic and Investigational Dermatology, 2017
- [Randomized controlled study for the anti-aging effect of human adipocyte-derived mesenchymal stem cell media combined with niacinamide after laser therapy](https://pubmed.ncbi.nlm.nih.gov/33103316/) Niacinamide · Journal of Cosmetic Dermatology, 2021
- [Reduction in the appearance of facial hyperpigmentation by topical N-acetyl glucosamine](https://pubmed.ncbi.nlm.nih.gov/17348991/) Acetyl glucosamine · Journal of Cosmetic Dermatology, 2007
- [Reduction in the appearance of facial hyperpigmentation after use of moisturizers with a combination of topical niacinamide and N-acetyl glucosamine: results of a randomized, double-blind, vehicle-controlled trial](https://pubmed.ncbi.nlm.nih.gov/19845667/) Acetyl glucosamine · The British Journal of Dermatology, 2010
- [The Herbal Bitter Drug Gentiana lutea Modulates Lipid Synthesis in Human Keratinocytes In Vitro and In Vivo](https://pubmed.ncbi.nlm.nih.gov/28829355/) Gentiana lutea root extract · International Journal of Molecular Sciences, 2017
- [The anti-wrinkle efficacy of argireline, a synthetic hexapeptide, in Chinese subjects: a randomized, placebo-controlled study](https://pubmed.ncbi.nlm.nih.gov/23417317/) Acetyl hexapeptide-8 · American Journal of Clinical Dermatology, 2013
- [Senomorphic activity of a combination of niacinamide and hyaluronic acid: correlation with clinical improvement of skin aging](https://pubmed.ncbi.nlm.nih.gov/39009698/) Niacinamide · Scientific Reports, 2024
- [A new topical panthenol-containing emollient: Results from two randomized controlled studies assessing its skin moisturization and barrier restoration potential, and the effect on skin microflora](https://pubmed.ncbi.nlm.nih.gov/27425824/) Panthenol · The Journal of Dermatological Treatment, 2017
- [A Double-Blinded, Randomized, Vehicle-Controlled Study of the Efficacy of Moisturizer Containing Licochalcone A, Decanediol, L-Carnitine, and Salicylic Acid for Prevention of Acne Relapse in Asian Population](https://pubmed.ncbi.nlm.nih.gov/33150170/) Salicylic acid · BioMed Research International, 2020
- [Another Reason for Using Caffeine in Dermocosmetics: Sunscreen Adjuvant](https://pubmed.ncbi.nlm.nih.gov/31130869/) Caffeine · Frontiers in Physiology, 2019
- [Treatment of xerosis with a topical formulation containing glyceryl glucoside, natural moisturizing factors, and ceramide](https://pubmed.ncbi.nlm.nih.gov/22916312/) Moisturizing factors nmf, Glyceryl glucoside · The Journal of Clinical and Aesthetic Dermatology, 2012
- [Comparative study of efficacy and safety of 45% mandelic acid versus 30% salicylic acid peels in mild-to-moderate acne vulgaris](https://pubmed.ncbi.nlm.nih.gov/31553119/) Mandelic acid · Journal of Cosmetic Dermatology, 2020
- [Sunscreens and Cosmetic Formulations Containing Ascorbyl Tetraisopalmitate and Rice Peptides for the Improvement of Skin Photoaging: A Double-blind, Randomized Placebo-controlled Clinical Study](https://pubmed.ncbi.nlm.nih.gov/33529350/) Tetrahexyldecyl ascorbate · Photochemistry and Photobiology, 2021
- [Clinical evidence of the efficacy and safety of a new 3-in-1 anti-aging topical night serum-in-oil containing melatonin, bakuchiol, and ascorbyl tetraisopalmitate: 103 females treated from 28 to 84 days](https://pubmed.ncbi.nlm.nih.gov/30924254/) Tetrahexyldecyl ascorbate · Journal of Cosmetic Dermatology, 2019
- [The efficacy of glycolic acid, salicylic acid, gluconolactone, and licochalcone A combined with 0.1% adapalene vs adapalene monotherapy in mild-to-moderate acne vulgaris: a double-blinded within-person comparative study](https://pubmed.ncbi.nlm.nih.gov/30858720/) Gluconolactone, Glycolic acid · Clinical, Cosmetic and Investigational Dermatology, 2019
- [Efficacy of a topical gel containing chitosan, chlorhexidine, allantoin and dexpanthenol for pain and inflammation control after third molar surgery: A randomized and placebo-controlled clinical trial](https://pubmed.ncbi.nlm.nih.gov/32683390/) Allantoin, Panthenol · Medicina Oral, Patologia Oral Y Cirugia Bucal, 2020
- [Anti-Wrinkle Efficacy of Cross-Linked Hyaluronic Acid-Based Microneedle Patch with Acetyl Hexapeptide-8 and Epidermal Growth Factor on Korean Skin](https://pubmed.ncbi.nlm.nih.gov/33911590/) Acetyl hexapeptide-8 · Annals of Dermatology, 2019
- [Systematic Study of Paeonol/Madecassoside Co-Delivery Nanoemulsion Transdermal Delivery System for Enhancing Barrier Repair and Anti-Inflammatory Efficacy](https://pubmed.ncbi.nlm.nih.gov/37446936/) Centella asiatica leaf extract · Molecules, 2023
- [A comparative study of gluconolactone versus benzoyl peroxide in the treatment of acne](https://pubmed.ncbi.nlm.nih.gov/1303072/) Gluconolactone · The Australasian Journal of Dermatology, 1992
- [The pivotal role of Bifida Ferment Lysate on reinforcing the skin barrier function and maintaining homeostasis of skin defenses in vitro](https://pubmed.ncbi.nlm.nih.gov/37218728/) Bifida lysate ferment · Journal of Cosmetic Dermatology, 2023
- [Anti-photoaging effects of flexible nanoliposomes encapsulated Moringa oleifera Lam. isothiocyanate in UVB-induced cell damage in HaCaT cells](https://pubmed.ncbi.nlm.nih.gov/35277099/) Moringa oleifera seed extract · Drug Delivery, 2022
- [Fatty acids based α-Tocopherol loaded nanostructured lipid carrier gel: In vitro and in vivo evaluation for moisturizing and anti-aging effects](https://pubmed.ncbi.nlm.nih.gov/32129554/) Vitamin e · Journal of Cosmetic Dermatology, 2020
- [Efficacy of a multitargeted, salicylic acid-based dermocosmetic cream compared to benzoyl peroxide 5% in Acne vulgaris: Results from a randomized study](https://pubmed.ncbi.nlm.nih.gov/37941097/) Salicylic acid · Journal of Cosmetic Dermatology, 2024
- [Evaluation of dermal extracellular matrix and epidermal-dermal junction modifications using matrix-assisted laser desorption/ionization mass spectrometric imaging, in vivo reflectance confocal microscopy, echography, and histology: effect of age and peptide applications](https://pubmed.ncbi.nlm.nih.gov/25817264/) Palmitoyl hexapeptide-12 · Journal of Cosmetic Dermatology, 2015
- [Antioxidant-based topical formulations influence on the inflammatory response of Japanese skin: A clinical study using non-invasive techniques](https://pubmed.ncbi.nlm.nih.gov/28385617/) Tetrahexyldecyl ascorbate · European Journal of Pharmaceutics and Biopharmaceutics, 2017
- [Efficacy of a topical serum containing L-ascorbic acid, neohesperidin, pycnogenol, tocopherol, and hyaluronic acid in relation to skin aging signs](https://pubmed.ncbi.nlm.nih.gov/35150043/) Vitamin e · Journal of Cosmetic Dermatology, 2022
- [A dermocosmetic containing bakuchiol, Ginkgo biloba extract and mannitol improves the efficacy of adapalene in patients with acne vulgaris: result from a controlled randomized trial](https://pubmed.ncbi.nlm.nih.gov/25914553/) Bakuchiol · Clinical, Cosmetic and Investigational Dermatology, 2015
- [Efficacy and safety of moisturizer containing 5% panthenol, madecassoside, and copper-zinc-manganese versus 0.02% triamcinolone acetonide cream in decreasing adverse reaction and downtime after ablative fractional carbon dioxide laser resurfacing: A split-face, double-blinded, randomized, controlled trial](https://pubmed.ncbi.nlm.nih.gov/30945430/) Centella asiatica leaf extract · Journal of Cosmetic Dermatology, 2019
- [Retaining Skin Barrier Function Properties of the Stratum Corneum with Components of the Natural Moisturizing Factor-A Randomized, Placebo-Controlled Double-Blind In Vivo Study](https://pubmed.ncbi.nlm.nih.gov/33809557/) Moisturizing factors nmf · Molecules, 2021
- [A Salicylic Acid-Based Dermocosmetic is Effective as an Adjunct to Benzoyl Peroxide for Mild to Moderate Acne and as Monotherapy in Maintenance Post Benzoyl Peroxide](https://pubmed.ncbi.nlm.nih.gov/38051857/) Salicylic acid · Journal of Drugs in Dermatology, 2023
- [Effects of 1,3-propanediol associated, or not, with butylene glycol and/or glycerol on skin hydration and skin barrier function](https://pubmed.ncbi.nlm.nih.gov/37699769/) Propanediol · International Journal of Cosmetic Science, 2024
- [Subclinical, non-erythematous irritation with an open assay model (washing): sodium lauryl sulfate (SLS) versus sodium laureth sulfate (SLES)](https://pubmed.ncbi.nlm.nih.gov/11278060/) Sodium laureth sulfate · Food and Chemical Toxicology, 2001
- [Excellent clinical results with a new preparation for chemical peeling in acne: 30% salicylic acid in polyethylene glycol vehicle](https://pubmed.ncbi.nlm.nih.gov/18363720/) Polyethylene · Dermatologic Surgery, 2008
- [Efficacy and Tolerability of Topical Nicotinamide Plus Antibacterial Adhesive Agents and Zinc-Pyrrolidone Carboxylic Acid Versus Placebo as an Adjuvant Treatment for Moderate Acne Vulgaris in Indonesia: A Multicenter, Double-blind, Randomized, Controlled Trial](https://pubmed.ncbi.nlm.nih.gov/32983333/) Zinc pca · The Journal of Clinical and Aesthetic Dermatology, 2020
- [Development of stable tocopherol succinate-loaded ethosomes to enhance transdermal permeation: In vitro and in vivo characterizations](https://pubmed.ncbi.nlm.nih.gov/35274433/) Vitamin e · Journal of Cosmetic Dermatology, 2022
- [Topical application of jojoba (Simmondsia chinensis L.) wax enhances the synthesis of pro-collagen III and hyaluronic acid and reduces inflammation in the ex-vivo human skin organ culture model](https://pubmed.ncbi.nlm.nih.gov/38344180/) Jojoba seed oil · Frontiers in Pharmacology, 2024
- [The efficacy study of the combination of tripeptide-10-citrulline and acetyl hexapeptide-3. A prospective, randomized controlled study](https://pubmed.ncbi.nlm.nih.gov/28150423/) Acetyl hexapeptide-8 · Journal of Cosmetic Dermatology, 2017
- [Antiacne and antiblotch activities of a formulated combination of Aloe barbadensis leaf powder, Garcinia mangostana peel extract, and Camellia sinensis leaf extract](https://pubmed.ncbi.nlm.nih.gov/31239743/) Camellia sinensis leaf extract · Clinical, Cosmetic and Investigational Dermatology, 2019
- [Safety assessment of cyclomethicone, cyclotetrasiloxane, cyclopentasiloxane, cyclohexasiloxane, and cycloheptasiloxane](https://pubmed.ncbi.nlm.nih.gov/22247236/) Cyclopentasiloxane · International Journal of Toxicology, 2011
- [Evaluation of moisturizing and irritation potential of sacha inchi oil](https://pubmed.ncbi.nlm.nih.gov/31441999/) Plukenetia volubilis seed oil · Journal of Cosmetic Dermatology, 2020
- [Assessment of Human Skin Gene Expression by Different Blends of Plant Extracts with Implications to Periorbital Skin Aging](https://pubmed.ncbi.nlm.nih.gov/30373163/) Narcissus tazetta bulb extract · International Journal of Molecular Sciences, 2018
- [Tolerance and efficacy of a product containing ellagic and salicylic acids in reducing hyperpigmentation and dark spots in comparison with 4% hydroquinone](https://pubmed.ncbi.nlm.nih.gov/23377328/) Pomegranate pericarp extract · Journal of Drugs in Dermatology, 2013
- [Topical microemulsion containing Punica granatum extract: its control over skin erythema and melanin in healthy Asian subjects](https://pubmed.ncbi.nlm.nih.gov/25610348/) Punica granatum extract · Postepy Dermatologii I Alergologii, 2014
- [A randomized, double-blind, vehicle-controlled study of a preparation containing undecylenoyl phenylalanine 2% in the treatment of solar lentigines](https://pubmed.ncbi.nlm.nih.gov/19874316/) Undecylenoyl phenylalanine · Clinical and Experimental Dermatology, 2010
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- [Emulgels Containing Perilla frutescens Seed Oil, Moringa oleifera Seed Oil, and Mixed Seed Oil: Microemulsion and Safety Assessment](https://pubmed.ncbi.nlm.nih.gov/35745923/) Moringa oleifera seed oil · Polymers, 2022
- [Assessment of the efficacy and safety of a new complex skin cream in Asian women: A controlled clinical trial](https://pubmed.ncbi.nlm.nih.gov/28512843/) Hydroxyresveratrol · Journal of Cosmetic Dermatology, 2017
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- [Propanediol (and) Caprylic Acid (and) Xylitol as a New Single Topical Active Ingredient against Acne: In Vitro and In Vivo Efficacy Assays](https://pubmed.ncbi.nlm.nih.gov/34771112/) Propanediol · Molecules, 2021
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## The brands

- American skincare: [Estée Lauder](https://lovi.care/skincare/sg/brands/estee-lauder)
- British skincare: [Medik8](https://lovi.care/skincare/sg/brands/medik8)

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## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this comparison: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/compare/estee-lauder-vs-medik8
- United Kingdom: https://lovi.care/skincare/uk/compare/estee-lauder-vs-medik8
- Ireland: https://lovi.care/skincare/ie/compare/estee-lauder-vs-medik8
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- Singapore: https://lovi.care/skincare/sg/compare/estee-lauder-vs-medik8 (this page)
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