# Cetaphil vs Galderma

Page: https://lovi.care/skincare/sg/compare/cetaphil-vs-galderma

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Singapore.

Cetaphil and Galderma are established skincare brands owned by the Galderma Group AG, with the American brand founded in 1947 and the Swiss counterpart established in 1981. The former is widely loved for its thoughtful range of cleansers, moisturizers, [serums](https://lovi.care/skincare/sg/ingredients/serum), sunscreens, and more, which are carefully formulated with nourishing ingredients like [glycerin](https://lovi.care/skincare/sg/ingredients/glycerin), [niacinamide](https://lovi.care/skincare/sg/ingredients/niacinamide), and [panthenol](https://lovi.care/skincare/sg/ingredients/panthenol) to suit combination skin and acne-prone skin best, while the latter focuses its offerings here on targeted serums. Both brands differ in their product scope and heritage, with the American brand providing everyday hydration and barrier support through glycerin and niacinamide, and the Swiss brand offering specialized acne gels.

Cetaphil is an American skincare brand founded in 1947 and owned by Galderma Group AG.

[en.wikipedia.org](https://en.wikipedia.org/wiki/Cetaphil) [cetaphil.co.uk](https://www.cetaphil.co.uk/why-cetaphil/our-story.html)

Galderma is a Swiss skincare brand founded in 1981 and owned by Galderma Group AG.

[en.wikipedia.org](https://en.wikipedia.org/wiki/Galderma)

This page compares some of the most popular Cetaphil and Galderma products; for every product of both brands, with a fit score for your own skin, [use the Lovi app](https://app.pora.ai/vqqJ/j1xj2b6o?af_sub2=compare&af_sub3=selection_note&af_sub4=pg0bb25b73a6).

### Popular Cetaphil vs Galderma products

#### Galderma

- [Epiduo Gel](https://lovi.care/skincare/sg/p/galderma/epiduo-gel/for/acne-prone-skin) — High fit
- [Benzac AC 5](https://lovi.care/skincare/sg/p/galderma/benzac-ac-5/for/oily-acne-prone-skin) — High fit
- [Benzac AC Mild Strength 2.5% Acne Gel](https://lovi.care/skincare/sg/p/galderma/benzac-ac-mild-strength-2-5-acne-gel/for/oily-acne-prone-skin) — High fit

#### Cetaphil

- [Gentle Skin Cleanser](https://lovi.care/skincare/sg/p/cetaphil/gentle-skin-cleanser/for/dry-skin) — Superior fit — [S$29.66 at Amazon](https://www.amazon.sg/dp/B099N3NM61?tag=lovi-care-web-product0e-22&linkCode=osi&th=1&psc=1)
- [Moisturizing Cream](https://lovi.care/skincare/sg/p/cetaphil/moisturizing-cream/for/dry-skin) — Average fit — [S$31.81 at Amazon](https://www.amazon.sg/dp/B099N1LC4R?tag=lovi-care-web-product0e-22&linkCode=osi&th=1&psc=1)
- [Daily Facial Cleanser](https://lovi.care/skincare/sg/p/cetaphil/daily-facial-cleanser/for/oily-skin) — Superior fit — [S$26.29 at Amazon](https://www.amazon.sg/dp/B099MSZX25?tag=lovi-care-web-product0e-22&linkCode=osi&th=1&psc=1)
- [Moisturizing Lotion](https://lovi.care/skincare/sg/p/cetaphil/moisturizing-lotion/for/sensitive-skin) — Average fit — [S$29.98 at Amazon](https://www.amazon.sg/dp/B099N2SLT9?tag=lovi-care-web-product0e-22&linkCode=osi&th=1&psc=1)
- [Gentle Exfoliating SA Cleanser](https://lovi.care/skincare/sg/p/cetaphil/gentle-exfoliating-sa-cleanser/for/acne-prone-skin) — High fit
- [Moisturising Cream](https://lovi.care/skincare/sg/p/cetaphil/moisturising-cream/for/dry-sensitive-skin) — Average fit
- [Gentle Cleansing Bar](https://lovi.care/skincare/sg/p/cetaphil/gentle-cleansing-bar/for/dry-skin) — High fit — [S$26.50 at Amazon](https://www.amazon.sg/dp/B004OCGZWW?tag=lovi-care-web-product0e-22&linkCode=osi&th=1&psc=1)
- [Extra Gentle Daily Scrub](https://lovi.care/skincare/sg/p/cetaphil/extra-gentle-daily-scrub/for/sensitive-skin) — Superior fit — [S$31.19 at Amazon](https://www.amazon.sg/dp/B077FZ112C?tag=lovi-care-web-product0e-22&linkCode=osi&th=1&psc=1)

## People Say

Cetaphil

Galderma

- Gentleness and sensitivity Mostly Mentioned Sometimes Noted “The only thing my reactive skin tolerates. — Cetaphil Gentle Skin Cleanser” “No breakouts since switching to this. — Cetaphil Gentle Skin Cleanser” “Lifesaver for my very sensitive skin — Cetaphil Gentle Cleansing Bar” “didn't burn my face — Galderma Benzac AC Mild Strength 2.5% Acne Gel”
- Acne clearing Not noted Mostly Mentioned “cleared up my skin — Galderma Benzac AC Mild Strength 2.5% Acne Gel” “cystic acne gone — Galderma Epiduo Gel” “cleared completely in 1 week — Galderma Benzac AC 5”
- Hydration and moisture Mostly Mentioned Not noted “cleared up flaky skin — Cetaphil Moisturizing Cream” “healed my dry patches — Cetaphil Moisturising Cream” “Leaves my face feeling soft, not tight. — Cetaphil Gentle Skin Cleanser”
- Breakout prevention Not noted Often Mentioned “stops new pimples — Galderma Epiduo Gel” “stopped all my acne — Galderma Benzac AC 5”
- Absorption and finish Often Mentioned Not noted “absorbs instantly — Cetaphil Moisturizing Lotion” “Absorbs quickly into skin without residue — Cetaphil Daily Hydrating Lotion” “absorbs quickly — Cetaphil Moisturizing Cream”
- Skin smoothing and texture Sometimes Noted Sometimes Noted “Skin felt softer after one use — Cetaphil Gentle Exfoliating SA Cleanser” “Skin feels instantly softer — Cetaphil Extra Gentle Daily Scrub” “skin feels smooth — Galderma Epiduo Gel”
- Drying effects Sometimes Noted Mostly Mentioned “Felt a little stripping on sensitive areas. — Cetaphil Oily Skin Cleanser” “Skin felt dehydrated after 30 minutes — Cetaphil Daily Hydrating Lotion” “dried out my cheeks — Cetaphil Daily Facial Cleanser” “skin flaking off — Galderma Epiduo Gel”
- Skin irritation and burning Rarely Noted Mostly Mentioned “Stings my face immediately after applying. — Cetaphil Daily Facial Moisturizer” “burned my face — Cetaphil Vitamin C Serum” “Harsh burning sensation — Cetaphil Daily Hydrating Lotion” “face on fire — Galderma Epiduo Gel”
- Initial purging and side effects Not noted Mostly Mentioned “got worse first — Galderma Epiduo Gel”
- Fabric bleaching Not noted Mostly Mentioned “bleached my towel — Galderma Benzac AC 5”

## Questions and answers

### Cetaphil or Galderma: which is better?

Cetaphil is better for gentleness, hydration, and absorption, offering products on this page that fit sensitive, combination, and acne-prone skin well. Galderma does better for acne clearing and breakout prevention, though its [serums](https://lovi.care/skincare/sg/ingredients/serum) may cause severe dryness and irritation.

### What is the difference between Cetaphil and Galderma?

Cetaphil focuses on gentleness and hydration with a wide range of fragrance-free products, while Galderma specializes in effective acne-clearing serums.

### Which is more affordable, Cetaphil or Galderma?

The provided page facts and reviews do not contain pricing or affordability information to compare Cetaphil and Galderma.

### Which causes fewer breakouts, Cetaphil or Galderma?

Galderma does better for breakout prevention than Cetaphil according to the review themes on this page.

### Between Cetaphil and Galderma, which brand is better suited for acne-prone skin and breakout prevention?

Galderma is better suited for acne-prone skin and breakout prevention, as its products on this page feature effective acne-clearing serums. Reviewers note that Galderma does better for acne clearing and breakout prevention, though it may cause severe dryness and peeling.

### How do the review themes compare regarding gentleness, skin irritation, and drying effects between Cetaphil and Galderma?

Cetaphil does better for gentleness, whereas Galderma does better for avoiding drying effects, though reviewers note that Cetaphil can cause drying effects, skin irritation, and burning.

### Which brand offers fragrance-free products, and how do their country of origin and founding years compare?

Both brands offer fragrance-free products, as every product listed for Galderma and 26 of the 27 Cetaphil products on this page list no fragrance. Cetaphil was founded in 1947 in the United States, whereas Galderma was founded in 1981 in Switzerland.

## Research behind their key ingredients

- [The effect of niacinamide on reducing cutaneous pigmentation and suppression of melanosome transfer](https://pubmed.ncbi.nlm.nih.gov/12100180/) Niacinamide, Gentlebright complex · The British Journal of Dermatology, 2002
- [Mechanistic Basis and Clinical Evidence for the Applications of Nicotinamide (Niacinamide) to Control Skin Aging and Pigmentation](https://pubmed.ncbi.nlm.nih.gov/34439563/) Niacinamide · Antioxidants, 2021
- [Benefits of topical hyaluronic acid for skin quality and signs of skin aging: From literature review to clinical evidence](https://pubmed.ncbi.nlm.nih.gov/36200921/) Hyaluronic acid, Sodium hyaluronate · Dermatologic Therapy, 2022
- [Topical use of dexpanthenol in skin disorders](https://pubmed.ncbi.nlm.nih.gov/12113650/) Panthenol, Panthenol vitamin b5 · American Journal of Clinical Dermatology, 2002
- [Topical ascorbic acid on photoaged skin. Clinical, topographical and ultrastructural evaluation: double-blind study vs. placebo](https://pubmed.ncbi.nlm.nih.gov/12823436/) Sodium ascorbyl phosphate ascorbic acid, Ascorbyl palmitate ascorbic acid · Experimental Dermatology, 2003
- [Anti-aging and brightening effects of a topical treatment containing vitamin C, vitamin E, and raspberry leaf cell culture extract: A split-face, randomized controlled trial](https://pubmed.ncbi.nlm.nih.gov/31975502/) Ascorbic acid, Tocopherol · Journal of Cosmetic Dermatology, 2020
- [Effects of menthol and cold on histamine-induced itch and skin reactions in man](https://pubmed.ncbi.nlm.nih.gov/7624016/) Peppermint leaf extract · Neuroscience Letters, 1995
- [Anti-microbial and -inflammatory activity and efficacy of phytosphingosine: an in vitro and in vivo study addressing acne vulgaris](https://pubmed.ncbi.nlm.nih.gov/18489348/) Phytosphingosine · International Journal of Cosmetic Science, 2007
- [Prospective, randomized, double-blind assessment of topical bakuchiol and retinol for facial photoageing](https://pubmed.ncbi.nlm.nih.gov/29947134/) Bakuchiol · The British Journal of Dermatology, 2019
- [Effects of ascorbic acid on gingival melanin pigmentation in vitro and in vivo](https://pubmed.ncbi.nlm.nih.gov/19186973/) Sodium ascorbyl phosphate ascorbic acid · Journal of Periodontology, 2009
- [Skin penetration and stabilization of formulations containing microfine titanium dioxide as physical UV filter](https://pubmed.ncbi.nlm.nih.gov/18503414/) Titanium dioxide · International Journal of Cosmetic Science, 2000
- [The effects of a topical gel containing chitosan, 0,2% chlorhexidine, allantoin and despanthenol on the wound healing process subsequent to impacted lower third molar extraction](https://pubmed.ncbi.nlm.nih.gov/27475700/) Allantoin · Medicina Oral, Patologia Oral Y Cirugia Bucal, 2016
- [Treatment of acne with a combination of propolis, tea tree oil, and Aloe vera compared to erythromycin cream: two double-blind investigations](https://pubmed.ncbi.nlm.nih.gov/30588129/) Aloe barbadensis leaf juice powder · Clinical Pharmacology, 2018
- [Alteration of barrier properties, stratum corneum ceramides and microbiome composition in response to lotion application on cosmetic dry skin](https://pubmed.ncbi.nlm.nih.gov/35340018/) Ceramides · Scientific Reports, 2022
- [Topical benzoyl peroxide for acne](https://pubmed.ncbi.nlm.nih.gov/32175593/) Benzoyl peroxide, Benzoyl peroxide 25mg g · The Cochrane Database of Systematic Reviews, 2020
- [Vitamin C mesotherapy versus topical application for gingival hyperpigmentation: a clinical and histopathological study](https://pubmed.ncbi.nlm.nih.gov/33966113/) Ascorbic acid · Clinical Oral Investigations, 2021
- [Ceramide 1 and ceramide 3 act synergistically on skin hydration and the transepidermal water loss of sodium lauryl sulfate-irritated skin](https://pubmed.ncbi.nlm.nih.gov/18717861/) Ceramide np · International Journal of Dermatology, 2008
- [Effects of Locally Applied Glycerol and Xylitol on the Hydration, Barrier Function and Morphological Parameters of the Skin](https://pubmed.ncbi.nlm.nih.gov/27349297/) Xylitol, Xylitylglucoside · Acta Dermato-venereologica, 2017
- [Effect of a topical antioxidant serum containing vitamin C, vitamin E, and ferulic acid after Q-switched 1064-nm Nd:YAG laser for treatment of environment-induced skin pigmentation](https://pubmed.ncbi.nlm.nih.gov/32052907/) Ascorbic acid · Journal of Cosmetic Dermatology, 2020
- [Green tea extract reduces induction of p53 and apoptosis in UVB-irradiated human skin independent of transcriptional controls](https://pubmed.ncbi.nlm.nih.gov/18631247/) Camellia sinensis leaf extract · Experimental Dermatology, 2009
- [Anti-inflammatory activities of colloidal oatmeal (Avena sativa) contribute to the effectiveness of oats in treatment of itch associated with dry, irritated skin](https://pubmed.ncbi.nlm.nih.gov/25607907/) Avena sativa kernel extract oat kernel extract · Journal of Drugs in Dermatology, 2015
- [The 24-hour skin hydration and barrier function effects of a hyaluronic 1%, glycerin 5%, and Centella asiatica stem cells extract moisturizing fluid: an intra-subject, randomized, assessor-blinded study](https://pubmed.ncbi.nlm.nih.gov/28860834/) Glycerin · Clinical, Cosmetic and Investigational Dermatology, 2017
- [Randomized controlled study for the anti-aging effect of human adipocyte-derived mesenchymal stem cell media combined with niacinamide after laser therapy](https://pubmed.ncbi.nlm.nih.gov/33103316/) Niacinamide, Gentlebright complex · Journal of Cosmetic Dermatology, 2021
- [Niacinamide mitigates SASP-related inflammation induced by environmental stressors in human epidermal keratinocytes and skin](https://pubmed.ncbi.nlm.nih.gov/32657437/) Gentlebright complex · International Journal of Cosmetic Science, 2020
- [The human stratum corneum layer: an effective barrier against dermal uptake of different forms of topically applied micronised titanium dioxide](https://pubmed.ncbi.nlm.nih.gov/11509913/) Titanium dioxide · Skin Pharmacology and Applied Skin Physiology, 2001
- [Prevention and Reduction of Atrophic Acne Scars with Adapalene 0.3%/Benzoyl Peroxide 2.5% Gel in Subjects with Moderate or Severe Facial Acne: Results of a 6-Month Randomized, Vehicle-Controlled Trial Using Intra-Individual Comparison](https://pubmed.ncbi.nlm.nih.gov/29549588/) Adapalene · American Journal of Clinical Dermatology, 2018
- [Benzoyl peroxide treatment decreases Cutibacterium acnes in shoulder surgery, from skin incision until wound closure](https://pubmed.ncbi.nlm.nih.gov/33545336/) Benzoyl peroxide, Benzoyl peroxide 25mg g · Journal of Shoulder and Elbow Surgery, 2021
- [Anti-Aging Effects of Leontopodium alpinum (Edelweiss) Callus Culture Extract Through Transcriptome Profiling](https://pubmed.ncbi.nlm.nih.gov/32098197/) Leontopodium alpinum extract · Genes, 2020
- [Efficacy and Safety of a Fixed-Dose Clindamycin Phosphate 1.2%, Benzoyl Peroxide 3.1%, and Adapalene 0.15% Gel for Moderate-to-Severe Acne: A Randomized Phase II Study of the First Triple-Combination Drug](https://pubmed.ncbi.nlm.nih.gov/34674160/) Benzoyl peroxide, Benzoyl peroxide 25mg g · American Journal of Clinical Dermatology, 2022
- [Two superior antioxidants: Ferulic acid and ascorbic acid in reducing signs of photoaging-A split-face comparative study](https://pubmed.ncbi.nlm.nih.gov/34877760/) Sodium ascorbyl phosphate ascorbic acid · Dermatologic Therapy, 2022
- [A new topical panthenol-containing emollient: Results from two randomized controlled studies assessing its skin moisturization and barrier restoration potential, and the effect on skin microflora](https://pubmed.ncbi.nlm.nih.gov/27425824/) Panthenol, Panthenol vitamin b5 · The Journal of Dermatological Treatment, 2017
- [Senomorphic activity of a combination of niacinamide and hyaluronic acid: correlation with clinical improvement of skin aging](https://pubmed.ncbi.nlm.nih.gov/39009698/) Niacinamide · Scientific Reports, 2024
- [A Double-Blinded, Randomized, Vehicle-Controlled Study of the Efficacy of Moisturizer Containing Licochalcone A, Decanediol, L-Carnitine, and Salicylic Acid for Prevention of Acne Relapse in Asian Population](https://pubmed.ncbi.nlm.nih.gov/33150170/) Salicylic acid · BioMed Research International, 2020
- [Stable Ozonides with Vitamin E Acetate versus Corticosteroid in the Treatment of Lichen Sclerosus in Foreskin: Evaluation of Effects on Inflammation](https://pubmed.ncbi.nlm.nih.gov/30991399/) Tocopheryl acetate vitamin e, Tocopheryl acetate vitamin e acetate · Urologia Internationalis, 2019
- [Ascorbic Acid Treatments as Effective and Safe Anti-Aging Therapies for Sensitive Skin](https://pubmed.ncbi.nlm.nih.gov/38397772/) Ascorbyl palmitate ascorbic acid · Antioxidants, 2024
- [Adenosine-loaded dissolving microneedle patches to improve skin wrinkles, dermal density, elasticity and hydration](https://pubmed.ncbi.nlm.nih.gov/29574973/) Adenosine · International Journal of Cosmetic Science, 2018
- [Comparative study of efficacy and safety of 45% mandelic acid versus 30% salicylic acid peels in mild-to-moderate acne vulgaris](https://pubmed.ncbi.nlm.nih.gov/31553119/) Mandelic acid · Journal of Cosmetic Dermatology, 2020
- [Another Reason for Using Caffeine in Dermocosmetics: Sunscreen Adjuvant](https://pubmed.ncbi.nlm.nih.gov/31130869/) Caffeine · Frontiers in Physiology, 2019
- [Structural characterization and in vivo evaluation of retinyl palmitate in non-ionic lamellar liquid crystalline system](https://pubmed.ncbi.nlm.nih.gov/21411295/) Retinyl palmitate · Colloids and Surfaces. B, Biointerfaces, 2011
- [A Dunaliella salina Extract Counteracts Skin Aging under Intense Solar Irradiation Thanks to Its Antiglycation and Anti-Inflammatory Properties](https://pubmed.ncbi.nlm.nih.gov/35200634/) Dunaliella salina extract · Marine Drugs, 2022
- [A topical gel of tea tree oil nanoemulsion containing adapalene versus adapalene marketed gel in patients with acne vulgaris: a randomized clinical trial](https://pubmed.ncbi.nlm.nih.gov/34251536/) Adapalene · Archives of Dermatological Research, 2022
- [Efficacy of a topical gel containing chitosan, chlorhexidine, allantoin and dexpanthenol for pain and inflammation control after third molar surgery: A randomized and placebo-controlled clinical trial](https://pubmed.ncbi.nlm.nih.gov/32683390/) Panthenol vitamin b5, Panthenol, Allantoin · Medicina Oral, Patologia Oral Y Cirugia Bucal, 2020
- [The efficacy of glycolic acid, salicylic acid, gluconolactone, and licochalcone A combined with 0.1% adapalene vs adapalene monotherapy in mild-to-moderate acne vulgaris: a double-blinded within-person comparative study](https://pubmed.ncbi.nlm.nih.gov/30858720/) Pha polyhydroxy acid · Clinical, Cosmetic and Investigational Dermatology, 2019
- [Development of Multifunctional Cosmetic Cream Using Bioactive Materials from Streptomyces sp. T65 with Synthesized Mesoporous Silica Particles SBA-15](https://pubmed.ncbi.nlm.nih.gov/32224894/) Silicon dioxide · Antioxidants, 2020
- [In vivo anti-ageing activity of cream containing niosomes loaded with purple glutinous rice (Oryza sativa Linn.) extract](https://pubmed.ncbi.nlm.nih.gov/32812663/) Rice extract lees extract · International Journal of Cosmetic Science, 2020
- [A comparative study of gluconolactone versus benzoyl peroxide in the treatment of acne](https://pubmed.ncbi.nlm.nih.gov/1303072/) Pha polyhydroxy acid · The Australasian Journal of Dermatology, 1992
- [Efficacy of a multitargeted, salicylic acid-based dermocosmetic cream compared to benzoyl peroxide 5% in Acne vulgaris: Results from a randomized study](https://pubmed.ncbi.nlm.nih.gov/37941097/) Salicylic acid · Journal of Cosmetic Dermatology, 2024
- [Biomimetic hyaluronic acid-stabilized zinc oxide nanoparticles in acne treatment: A preclinical and clinical approach](https://pubmed.ncbi.nlm.nih.gov/40254135/) Zinc oxide · Journal of Controlled Release, 2025
- [Fatty acids based α-Tocopherol loaded nanostructured lipid carrier gel: In vitro and in vivo evaluation for moisturizing and anti-aging effects](https://pubmed.ncbi.nlm.nih.gov/32129554/) Vitamin e · Journal of Cosmetic Dermatology, 2020
- [A Lipid Mixture Enriched by Ceramide NP with Fatty Acids of Diverse Chain Lengths Contributes to Restore the Skin Barrier Function Impaired by Topical Corticosteroid](https://pubmed.ncbi.nlm.nih.gov/34348350/) Ceramide np · Skin Pharmacology and Physiology, 2022
- [Comparison of clinical efficacies of sodium ascorbyl phosphate, retinol and their combination in acne treatment](https://pubmed.ncbi.nlm.nih.gov/19134126/) Sodium ascorbyl phosphate · International Journal of Cosmetic Science, 2009
- [Formulating octyl methoxycinnamate in hybrid lipid-silica nanoparticles: An innovative approach for UV skin protection](https://pubmed.ncbi.nlm.nih.gov/32395645/) Silicon dioxide · Heliyon, 2020
- [A Salicylic Acid-Based Dermocosmetic is Effective as an Adjunct to Benzoyl Peroxide for Mild to Moderate Acne and as Monotherapy in Maintenance Post Benzoyl Peroxide](https://pubmed.ncbi.nlm.nih.gov/38051857/) Salicylic acid · Journal of Drugs in Dermatology, 2023
- [Colloidal Oatmeal <em>(Avena Sativa)</em> Improves Skin Barrier Through Multi-Therapy Activity](https://pubmed.ncbi.nlm.nih.gov/27272074/) Avena sativa kernel extract oat kernel extract · Journal of Drugs in Dermatology, 2016
- [Efficacy of a topical serum containing L-ascorbic acid, neohesperidin, pycnogenol, tocopherol, and hyaluronic acid in relation to skin aging signs](https://pubmed.ncbi.nlm.nih.gov/35150043/) Vitamin e · Journal of Cosmetic Dermatology, 2022
- [Clindamycin phosphate 1.2%/adapalene 0.15%/benzoyl peroxide 3.1% gel for moderate-to-severe acne: Efficacy and safety results from two randomized phase 3 trials](https://pubmed.ncbi.nlm.nih.gov/37656094/) Adapalene · Journal of the American Academy of Dermatology, 2023
- [Efficacy and safety of microencapsulated benzoyl peroxide and microencapsulated tretinoin for the treatment of acne vulgaris: Results from two phase 3 double-blind, randomized, vehicle-controlled studies](https://pubmed.ncbi.nlm.nih.gov/37356627/) Benzoyl peroxide, Benzoyl peroxide 25mg g · Journal of the American Academy of Dermatology, 2023
- [Semi-Solid Dosage Forms Containing Pranoprofen-Loaded NLC as Topical Therapy for Local Inflammation: In Vitro, Ex Vivo and In Vivo Evaluation](https://pubmed.ncbi.nlm.nih.gov/37367119/) Carbomer 940 · Gels, 2023
- [Botulinum toxin injection as a single or combined treatment with non-cross-linked high molecular weight and low molecular weight hyaluronic acid gel for neck rejuvenation: A randomized clinical trial](https://pubmed.ncbi.nlm.nih.gov/35775872/) Hydrolyzed hyaluronic acid · Dermatologic Therapy, 2022
- [Subclinical, non-erythematous irritation with an open assay model (washing): sodium lauryl sulfate (SLS) versus sodium laureth sulfate (SLES)](https://pubmed.ncbi.nlm.nih.gov/11278060/) Sodium laureth sulfate · Food and Chemical Toxicology, 2001
- [In Vitro and Clinical Safety Assessment of the Multiple W/O/W Emulsion Based on the Active Ingredients from Rosmarinus officinalis L., Avena sativa L. and Linum usitatissimum L](https://pubmed.ncbi.nlm.nih.gov/34065623/) Avena sativa kernel extract oat kernel extract · Pharmaceutics, 2021
- [Whitening effect of alpha-bisabolol in Asian women subjects](https://pubmed.ncbi.nlm.nih.gov/20642768/) Bisabolol · International Journal of Cosmetic Science, 2010
- [Clinical evaluation of the efficacy of a facial serum containing dioic acid, glycolic acid, salicylic acid, LHA, citric acid, and HEPES in treating post-inflammatory hyperchromia and controlling oily skin in patients with acne vulgaris](https://pubmed.ncbi.nlm.nih.gov/33617668/) Citric acid · Journal of Cosmetic Dermatology, 2021
- [Assessment of Combined Ascorbyl Palmitate (AP) and Sodium Ascorbyl Phosphate (SAP) on Facial Skin Sebum Control in Female Healthy Volunteers](https://pubmed.ncbi.nlm.nih.gov/27756097/) Sodium ascorbyl phosphate · Drug Research, 2017
- [The impacts of sodium lauroyl sarcosinate in facial cleanser on facial skin microbiome and lipidome](https://pubmed.ncbi.nlm.nih.gov/37990616/) Sodium lauroyl sarcosinate · Journal of Cosmetic Dermatology, 2024
- [Two-phase delivery using a horse oil and adenosine-loaded dissolving microneedle patch for skin barrier restoration, moisturization, and wrinkle improvement](https://pubmed.ncbi.nlm.nih.gov/30160014/) Adenosine · Journal of Cosmetic Dermatology, 2019
- [Synergetic Effects of Aloe Vera Extract with Trimethylglycine for Targeted Aquaporin 3 Regulation and Long-Term Skin Hydration](https://pubmed.ncbi.nlm.nih.gov/38611819/) Betaine · Molecules, 2024
- [Supramolecular collagen nanoparticles for anti-wrinkle, skin whitening, and moisturizing effects](https://pubmed.ncbi.nlm.nih.gov/39383579/) Palmitoyl tripeptide-5 · Colloids and Surfaces. B, Biointerfaces, 2025
- [Why is sodium cocoyl isethionate (SCI) mild to the skin barrier? - An in vitro investigation based on the relative sizes of the SCI micelles and the skin aqueous pores](https://pubmed.ncbi.nlm.nih.gov/17598025/) Sodium cocoyl isethionate · Journal of Cosmetic Science, 2007
- [Influence of vitamin E acetate on stratum corneum hydration](https://pubmed.ncbi.nlm.nih.gov/9706379/) Tocopheryl acetate vitamin e, Tocopheryl acetate · Arzneimittel-Forschung, 1998
- [The use of different concentrations of betaine as a reducing irritation agent in soaps monitored visually and non-invasively](https://pubmed.ncbi.nlm.nih.gov/12535284/) Betaine · Skin Research and Technology, 2003
- [Lactobionic acid in a natural alkylpolyglucoside-based vehicle: assessing safety and efficacy aspects in comparison to glycolic acid](https://pubmed.ncbi.nlm.nih.gov/20367666/) Pha polyhydroxy acid · Journal of Cosmetic Dermatology, 2010
- [Clinical efficacy and safety of nano-microneedle-assisted phenylethyl resorcinol for the treatment of infraorbital dark circles](https://pubmed.ncbi.nlm.nih.gov/32783330/) Phenylethyl resorcinol · Journal of Cosmetic Dermatology, 2021
- [Comparative physicochemical stability and clinical anti-wrinkle efficacy of transdermal emulgel preparations of 5% sodium ascorbyl phosphate and or ascorbic acid on human volunteers](https://pubmed.ncbi.nlm.nih.gov/32383548/) Sodium ascorbyl phosphate · Journal of Cosmetic Dermatology, 2021
- [Topical prevention from high energy visible light-induced pigmentation by 2-mercaptonicotinoyl glycine, but not by ascorbic acid antioxidant: 2 randomized controlled trials](https://pubmed.ncbi.nlm.nih.gov/41142247/) Ascorbyl palmitate ascorbic acid · Frontiers in Pharmacology, 2025
- [Topical Zinc Oxide Nanoparticle Formulations for Acne Vulgaris: A Systematic Review of Pre-Clinical and Early-Phase Clinical Evidence](https://pubmed.ncbi.nlm.nih.gov/41007718/) Zinc oxide · Biomedicines, 2025
- [Modulation of lipid fluidity likely contributes to the fructose/xylitol-induced acceleration of epidermal permeability barrier recovery](https://pubmed.ncbi.nlm.nih.gov/30847563/) Xylitylglucoside · Archives of Dermatological Research, 2019
- [Evaluation of the Efficacy and Safety of a Panthenol-Enriched Mask for Skin Barrier Recovery After Facial Laser Treatment: Results of a Double-Blind Randomized Controlled Study](https://pubmed.ncbi.nlm.nih.gov/40613435/) Panthenol, Panthenol vitamin b5 · Journal of Cosmetic Dermatology, 2025
- [Safety of a preservative system containing 1,2-hexanediol and caprylyl glycol](https://pubmed.ncbi.nlm.nih.gov/19514921/) Caprylyl glycol · Cutaneous and Ocular Toxicology, 2009
- [Efficacy and Tolerability of Stable Hybrid Cooperative Complexes of High- and Low-Molecular Weight Hyaluronic Acid in Asian Patients: An Open-Label Study](https://pubmed.ncbi.nlm.nih.gov/40921777/) Hydrolyzed hyaluronic acid · Aesthetic Plastic Surgery, 2026
- [Modulation of skin pigmentation by the tetrapeptide PKEK: in vitro and in vivo evidence for skin whitening effects](https://pubmed.ncbi.nlm.nih.gov/22142309/) Sodium ascorbyl phosphate · Experimental Dermatology, 2012
- [Tocopherol succinate-loaded ethosomal gel synthesized by cold method technique: Deeper biophysical characterizations for translational application on human skin](https://pubmed.ncbi.nlm.nih.gov/38268219/) Vitamin e · Journal of Cosmetic Dermatology, 2024
- [The effect of a vitamin A palmitate and antioxidant-containing oil-based moisturizer on photodamaged skin of several body sites](https://pubmed.ncbi.nlm.nih.gov/23438139/) Retinyl palmitate · Journal of Cosmetic Dermatology, 2013
- [Modulating effects of oatmeal extracts in the sodium lauryl sulfate skin irritancy model](https://pubmed.ncbi.nlm.nih.gov/11867969/) Avena sativa kernel extract oat kernel extract · Skin Pharmacology and Applied Skin Physiology, 2002
- [Propanediol (and) Caprylic Acid (and) Xylitol as a New Single Topical Active Ingredient against Acne: In Vitro and In Vivo Efficacy Assays](https://pubmed.ncbi.nlm.nih.gov/34771112/) Xylitylglucoside · Molecules, 2021
- [Nanostructured Lipid Carrier Based Gel Containing α-Tocopherol and α-Tocopheryl Acetate for Synergistic Cutaneous Antiaging Efficacy](https://pubmed.ncbi.nlm.nih.gov/41309687/) Tocopheryl acetate vitamin e, Tocopheryl acetate vitamin e acetate, Tocopheryl acetate · Scientific Reports, 2025
- [Nanocomplex of quaternized cyclodextrin grafted chitosan and hyaluronic acid for a skin delivery](https://pubmed.ncbi.nlm.nih.gov/36279763/) Hydrolyzed hyaluronic acid · Colloids and Surfaces. B, Biointerfaces, 2022
- [Translational Evaluation of a Disodium Adenosine Monophosphate (AMP2Na)-Based Topical Formulation for Physiology-Aligned Skin Rejuvenation: Integrated In Vitro, Ex Vivo, and Clinical Evidence](https://pubmed.ncbi.nlm.nih.gov/42278371/) Adenosine · International Journal of Molecular Sciences, 2026
- [Evaulation of irritation potential of surfactant mixtures](https://pubmed.ncbi.nlm.nih.gov/18503452/) Sodium laureth sulfate · International Journal of Cosmetic Science, 1999
- [Safety assessment on comedogenicity of dermatological products containing d-alpha tocopheryl acetate in Asian subjects: A double-blind randomized controlled trial](https://pubmed.ncbi.nlm.nih.gov/34471722/) Tocopheryl acetate vitamin e, Tocopheryl acetate · Contemporary Clinical Trials Communications, 2021
- [Facial disbiosis and UV filters](https://pubmed.ncbi.nlm.nih.gov/39499337/) Octocrylene · Archives of Dermatological Research, 2024
- [A polyhydroxy acid skin care regimen provides antiaging effects comparable to an alpha-hydroxyacid regimen](https://pubmed.ncbi.nlm.nih.gov/15002657/) Pha polyhydroxy acid · Cutis, 2004
- [A Randomized Controlled Trial of the Genistein Plus Bakuchiol and Vitamins (GEN+) Product for Male Facial Skin: Effects on Skin Appearance and Properties](https://pubmed.ncbi.nlm.nih.gov/41562471/) Bakuchiol · Skin Research and Technology, 2026
- [Synergistic combination: Developing a natural carrier-free assembled gel through hydrogen bond reconstruction strategy for efficient skin photo-damage restoration](https://pubmed.ncbi.nlm.nih.gov/41129958/) Sodium pca · Biomaterials Advances, 2026
- [Efficacy of a Topical Formulation on Skin Hydration and Barrier Function in Individuals With Xerosis: A 28-Day Randomized, Split-Leg, Untreated-Controlled Trial](https://pubmed.ncbi.nlm.nih.gov/42108609/) Dipotassium glycyrrhizate · Journal of Cosmetic Dermatology, 2026
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## The brands

- American skincare: [Cetaphil](https://lovi.care/skincare/sg/brands/cetaphil)
- Swiss skincare: [Galderma](https://lovi.care/skincare/sg/brands/galderma)

## More comparisons

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- [Anua vs Cetaphil](https://lovi.care/skincare/sg/compare/anua-vs-cetaphil)
- [Anua vs Galderma](https://lovi.care/skincare/sg/compare/anua-vs-galderma)
- [Medicube vs Cetaphil](https://lovi.care/skincare/sg/compare/medicube-vs-cetaphil)
- [Medicube vs Galderma](https://lovi.care/skincare/sg/compare/medicube-vs-galderma)
- [The Ordinary vs Cetaphil](https://lovi.care/skincare/sg/compare/the-ordinary-vs-cetaphil)
- [The Ordinary vs Galderma](https://lovi.care/skincare/sg/compare/the-ordinary-vs-galderma)
- [Beauty of Joseon vs Cetaphil](https://lovi.care/skincare/sg/compare/beauty-of-joseon-vs-cetaphil)
- [Beauty of Joseon vs Galderma](https://lovi.care/skincare/sg/compare/beauty-of-joseon-vs-galderma)
- [COSRX vs Cetaphil](https://lovi.care/skincare/sg/compare/cosrx-vs-cetaphil)
- [COSRX vs Galderma](https://lovi.care/skincare/sg/compare/cosrx-vs-galderma)
- [CeraVe vs Cetaphil](https://lovi.care/skincare/sg/compare/cerave-vs-cetaphil)
- [CeraVe vs Galderma](https://lovi.care/skincare/sg/compare/cerave-vs-galderma)
- [La Roche-Posay vs Cetaphil](https://lovi.care/skincare/sg/compare/la-roche-posay-vs-cetaphil)
- [La Roche-Posay vs Galderma](https://lovi.care/skincare/sg/compare/la-roche-posay-vs-galderma)
- [Dr. Althea vs Cetaphil](https://lovi.care/skincare/sg/compare/dr-althea-vs-cetaphil)
- [Dr. Althea vs Galderma](https://lovi.care/skincare/sg/compare/dr-althea-vs-galderma)
- [Some By Mi vs Cetaphil](https://lovi.care/skincare/sg/compare/some-by-mi-vs-cetaphil)
- [Some By Mi vs Galderma](https://lovi.care/skincare/sg/compare/some-by-mi-vs-galderma)

## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this comparison: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/compare/cetaphil-vs-galderma
- United Kingdom: https://lovi.care/skincare/uk/compare/cetaphil-vs-galderma
- Ireland: https://lovi.care/skincare/ie/compare/cetaphil-vs-galderma
- Germany: https://lovi.care/skincare/de/compare/cetaphil-vs-galderma
- France: https://lovi.care/skincare/fr/compare/cetaphil-vs-galderma
- Italy: https://lovi.care/skincare/it/compare/cetaphil-vs-galderma
- Netherlands: https://lovi.care/skincare/nl/compare/cetaphil-vs-galderma
- Spain: https://lovi.care/skincare/es/compare/cetaphil-vs-galderma
- Canada: https://lovi.care/skincare/ca/compare/cetaphil-vs-galderma
- Australia: https://lovi.care/skincare/au/compare/cetaphil-vs-galderma
- Singapore: https://lovi.care/skincare/sg/compare/cetaphil-vs-galderma (this page)
- Saudi Arabia: https://lovi.care/skincare/sa/compare/cetaphil-vs-galderma
- United Arab Emirates: https://lovi.care/skincare/ae/compare/cetaphil-vs-galderma