# Azclear vs NEOCUTIS

Page: https://lovi.care/skincare/sg/compare/azclear-vs-neocutis

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Singapore.

Azclear and NEOCUTIS are skincare lines known for soothing [serums](https://lovi.care/skincare/sg/ingredients/serum), moisturizers, and balanced formulas. Azclear features gentle, soothing serums and the Medicated Lotion that suit sensitive, acne-prone, and reactive skin best, while the Swiss brand NEOCUTIS offers refined serums and moisturizers, including Bio Serum Firm and lumière, that suit mature, dry, and stressed skin best. Both brands nurture the complexion with thoughtful formulations, but differ in their specific targeted concerns and core restorative properties.

NEOCUTIS is a Swiss skincare brand founded in 2003 and owned by Merz Holding GmbH & Co. KG since 2013.

[businesswire.com](https://www.businesswire.com/news/home/20260716926041/en/Merz-Completes-Inaugural-%E2%82%AC450-Million-Schuldschein-Loan-Issuance) [gcimagazine.com](https://www.gcimagazine.com/brands-products/skin-care/news/21870673/merz-to-purchase-neocutis)

This page compares some of the most popular Azclear and NEOCUTIS products; for every product of both brands, with a fit score for your own skin, [use the Lovi app](https://app.pora.ai/vqqJ/j1xj2b6o?af_sub2=compare&af_sub3=selection_note&af_sub4=pg935fe91504).

### Popular Azclear vs NEOCUTIS products

#### NEOCUTIS

- [Bio Serum Firm](https://lovi.care/skincare/sg/p/neocutis/bio-serum-firm/for/mature-skin) — High fit
- [lumière](https://lovi.care/skincare/sg/p/neocutis/lumiere/for/dry-skin) — Average fit

#### Azclear

- [Medicated Lotion](https://lovi.care/skincare/sg/p/azclear/medicated-lotion/for/oily-acne-prone-skin) — High fit

## Questions and answers

### Azclear or NEOCUTIS: which is better?

NEOCUTIS Bio [Serum](https://lovi.care/skincare/sg/ingredients/serum) Firm has a High Lovi fit for mature and dry skin, while Azclear Medicated Lotion has a High fit for oily acne-prone skin. Both brands have no fragrance in the products on this page.

### What is the difference between Azclear and NEOCUTIS?

Azclear has a High fit for oily acne-prone skin with its Medicated Lotion, whereas NEOCUTIS achieves a High fit for mature, dry, and sensitive skin through products like Bio Serum Firm. Both brands offer fragrance-free formulations across the products on this page.

[Pharmaceutics, 2021](https://pubmed.ncbi.nlm.nih.gov/33923739/)

### Which is more affordable, Azclear or NEOCUTIS?

The products on this page do not list pricing information, so a comparison of affordability cannot be made between Azclear and NEOCUTIS.

### Which causes fewer breakouts, Azclear or NEOCUTIS?

Azclear Medicated Lotion has a High Lovi fit for oily acne-prone skin, whereas NEOCUTIS Bio Serum Firm and lumière have an Average fit for acne-prone skin.

[Pharmaceutics, 2021](https://pubmed.ncbi.nlm.nih.gov/33923739/)

### When were Azclear and NEOCUTIS founded and who owns them?

Azclear was founded in 2010 and is owned by Ego Pharmaceuticals, while NEOCUTIS was founded in Switzerland in 2003 and has been owned by Merz Holding GmbH & Co. KG since 2013.

### Which products do Azclear and NEOCUTIS offer on this page and what are their types?

Azclear offers Medicated Lotion, which is a serum, while NEOCUTIS offers Bio Serum Firm, a serum, and lumière, a moisturizer.

### Do Azclear and NEOCUTIS products contain fragrance in their ingredients?

Every product on this page from both Azclear and NEOCUTIS lists no fragrance in its ingredients.

## Research behind their key ingredients

- [Benefits of topical hyaluronic acid for skin quality and signs of skin aging: From literature review to clinical evidence](https://pubmed.ncbi.nlm.nih.gov/36200921/) Hyaluronic acid · Dermatologic Therapy, 2022
- [Vitamin C-squalene bioconjugate promotes epidermal thickening and collagen production in human skin](https://pubmed.ncbi.nlm.nih.gov/33037252/) Squalane · Scientific Reports, 2020
- [Efficacy and Safety of Azelaic Acid Nanocrystal-Loaded In Situ Hydrogel in the Treatment of Acne Vulgaris](https://pubmed.ncbi.nlm.nih.gov/33923739/) Azelaic acid · Pharmaceutics, 2021
- [The 24-hour skin hydration and barrier function effects of a hyaluronic 1%, glycerin 5%, and Centella asiatica stem cells extract moisturizing fluid: an intra-subject, randomized, assessor-blinded study](https://pubmed.ncbi.nlm.nih.gov/28860834/) Glycerin · Clinical, Cosmetic and Investigational Dermatology, 2017
- [Inhibition of TRPV1 prevented skin irritancy induced by phenoxyethanol. A preliminary in vitro and in vivo study](https://pubmed.ncbi.nlm.nih.gov/27168163/) Phenoxyethanol · International Journal of Cosmetic Science, 2017
- [Evaluation of dermal extracellular matrix and epidermal-dermal junction modifications using matrix-assisted laser desorption/ionization mass spectrometric imaging, in vivo reflectance confocal microscopy, echography, and histology: effect of age and peptide applications](https://pubmed.ncbi.nlm.nih.gov/25817264/) Palmitoyl tripeptide-1 acetate, Palmitoyl tetrapeptide-7 · Journal of Cosmetic Dermatology, 2015
- [Effects of 15% Azelaic Acid Gel in the Management of Post-Inflammatory Erythema and Post-Inflammatory Hyperpigmentation in Acne Vulgaris](https://pubmed.ncbi.nlm.nih.gov/38734843/) Azelaic acid · Dermatology and Therapy, 2024
- [The usefulness of a dermocosmetic containing Myrtus communis extract and azelaic acid for maintenance phase of adult female acne: Results from a randomized exploratory investigator-blinded comparative study](https://pubmed.ncbi.nlm.nih.gov/36729399/) Azelaic acid · Journal of the European Academy of Dermatology and Venereology, 2023
- [Squalane as a Promising Agent Protecting UV-Induced Inhibition of Collagen Biosynthesis and Wound Healing in Human Dermal Fibroblast](https://pubmed.ncbi.nlm.nih.gov/40363772/) Squalane · Molecules, 2025
- [Influence of vitamin E acetate on stratum corneum hydration](https://pubmed.ncbi.nlm.nih.gov/9706379/) Tocopheryl acetate · Arzneimittel-Forschung, 1998
- [Nanostructured Lipid Carrier Based Gel Containing α-Tocopherol and α-Tocopheryl Acetate for Synergistic Cutaneous Antiaging Efficacy](https://pubmed.ncbi.nlm.nih.gov/41309687/) Tocopheryl acetate · Scientific Reports, 2025
- [Targeting Circadian Rhythm for the Regulation of Skin Collagen Metabolism](https://pubmed.ncbi.nlm.nih.gov/41527525/) Palmitoyl tripeptide-1 acetate, Palmitoyl tripeptide-1 · Journal of Cosmetic Dermatology, 2026
- [Mechanistic understanding and peptide ingredient screening for type III collagen via biological knowledge graph and molecular docking](https://pubmed.ncbi.nlm.nih.gov/42683869/) Palmitoyl tripeptide-1 acetate · International Journal of Cosmetic Science, 2026

## The brands

- Skincare: [Azclear](https://lovi.care/skincare/sg/brands/azclear)
- Swiss skincare: [NEOCUTIS](https://lovi.care/skincare/sg/brands/neocutis)

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- [La Roche-Posay vs Azclear](https://lovi.care/skincare/sg/compare/la-roche-posay-vs-azclear)
- [La Roche-Posay vs NEOCUTIS](https://lovi.care/skincare/sg/compare/la-roche-posay-vs-neocutis)
- [Dr. Althea vs Azclear](https://lovi.care/skincare/sg/compare/dr-althea-vs-azclear)
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- [Some By Mi vs Azclear](https://lovi.care/skincare/sg/compare/some-by-mi-vs-azclear)
- [Some By Mi vs NEOCUTIS](https://lovi.care/skincare/sg/compare/some-by-mi-vs-neocutis)

## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this comparison: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/compare/azclear-vs-neocutis
- United Kingdom: https://lovi.care/skincare/uk/compare/azclear-vs-neocutis
- Ireland: https://lovi.care/skincare/ie/compare/azclear-vs-neocutis
- Germany: https://lovi.care/skincare/de/compare/azclear-vs-neocutis
- France: https://lovi.care/skincare/fr/compare/azclear-vs-neocutis
- Italy: https://lovi.care/skincare/it/compare/azclear-vs-neocutis
- Netherlands: https://lovi.care/skincare/nl/compare/azclear-vs-neocutis
- Spain: https://lovi.care/skincare/es/compare/azclear-vs-neocutis
- Canada: https://lovi.care/skincare/ca/compare/azclear-vs-neocutis
- Australia: https://lovi.care/skincare/au/compare/azclear-vs-neocutis
- Singapore: https://lovi.care/skincare/sg/compare/azclear-vs-neocutis (this page)
- Saudi Arabia: https://lovi.care/skincare/sa/compare/azclear-vs-neocutis
- United Arab Emirates: https://lovi.care/skincare/ae/compare/azclear-vs-neocutis
