# Avène vs Azclear

Page: https://lovi.care/skincare/sg/compare/avene-vs-azclear

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Singapore.

Avène and Azclear are distinct skincare brands designed to nurture diverse complexions with care. The French brand, founded in 1990 and owned by Fondation Pierre Fabre, is known for its gentle moisturizers, protective sunscreens, targeted [serums](https://lovi.care/skincare/sg/ingredients/serum), and soothing cleansers formulated with [glycerin](https://lovi.care/skincare/sg/ingredients/glycerin), suiting oily acne-prone skin and combination skin best through standouts like the Tolerance Control Soothing Skin Recovery Balm, the Cleanance, and the [Hyaluron](https://lovi.care/skincare/sg/ingredients/hyaluronic-acid) Activ B3 Concentrated Plumping Serum. Meanwhile, the other is deeply appreciated for its soothing serums and carefully balanced formulas, such as the Medicated Lotion, which suit sensitive, acne-prone, and reactive skin types best. While both offer thoughtful formulations, glycerin improves hydration and restores barrier function for the first, whereas the gentle nature of the second focuses on nurturing and balancing the complexion.

Avène is a French skincare brand founded in 1990 and owned by Fondation Pierre Fabre.

[pierre-fabre.com](https://www.pierre-fabre.com/en/our-company/governance) [avene.co.uk](https://www.avene.co.uk/a/water-that-makes-all-the-difference-thermal-spring-water) [aveneusa.com](https://www.aveneusa.com/history)

This page compares some of the most popular Avène and Azclear products; for every product of both brands, with a fit score for your own skin, [use the Lovi app](https://app.pora.ai/vqqJ/j1xj2b6o?af_sub2=compare&af_sub3=selection_note&af_sub4=pg5e365b85c5).

### Popular Avène vs Azclear products

#### Avène

- [Cicalfate+ Restorative Protective Cream](https://lovi.care/skincare/sg/p/avene/cicalfate-restorative-protective-cream/for/dry-skin) — High fit — [S$26.35 at YesStyle](https://www.yesstyle.com/en/avene-cicalfate-restorative-protective-cream-40ml/info.html/pid.1133246374?curr=SGD&rco=SG)
- [Cleanance](https://lovi.care/skincare/sg/p/avene/cleanance/for/oily-skin) — Superior fit — [S$27.51 at Amazon](https://www.amazon.sg/dp/B01MQWXZNV?tag=lovi-care-web-product0e-22&linkCode=osi&th=1&psc=1)
- [Cleanance Cleansing Gel](https://lovi.care/skincare/sg/p/avene/cleanance-cleansing-gel/for/oily-acne-prone-skin) — High fit — [S$27.51 at Amazon](https://www.amazon.sg/dp/B01MQWXZNV?tag=lovi-care-web-product0e-22&linkCode=osi&th=1&psc=1)
- [Hydrance+](https://lovi.care/skincare/sg/p/avene/hydrance/for/dry-sensitive-skin) — Average fit
- [Tolerance Control Soothing Skin Recovery Balm](https://lovi.care/skincare/sg/p/avene/tolerance-control-soothing-skin-recovery-balm/for/dry-skin) — Superior fit — [S$50.68 at Amazon](https://www.amazon.sg/dp/B08XYVMRP7?tag=lovi-care-web-product0e-22&linkCode=osi&th=1&psc=1)
- [RetrinAL EYES](https://lovi.care/skincare/sg/p/avene/retrinal-eyes/for/dry-skin) — High fit
- [Cold Cream](https://lovi.care/skincare/sg/p/avene/cold-cream/for/dry-sensitive-skin) — High fit
- [Vitamin Activ Cg Radiance Concentrated Serum](https://lovi.care/skincare/sg/p/avene/vitamin-activ-cg-radiance-concentrated-serum/for/mature-skin) — High fit

#### Azclear

- [Medicated Lotion](https://lovi.care/skincare/sg/p/azclear/medicated-lotion/for/oily-acne-prone-skin) — High fit

## Questions and answers

### Avène or Azclear: which is better?

Avène is better for a wider variety of skin concerns and types because the products on this page cover multiple routines, whereas Azclear features only a single medicated lotion.

### What is the difference between Avène and Azclear?

Avène is a French brand offering a wide range of fifteen products on this page featuring key ingredients like [thermal water](https://lovi.care/skincare/sg/ingredients/thermal-water) and [glycerin](https://lovi.care/skincare/sg/ingredients/glycerin) with varying Lovi fit levels, while Azclear is an Ego Pharmaceuticals brand featuring a single fragrance-free medicated lotion with a High Lovi fit for oily acne-prone skin.

### Which is more affordable, Avène or Azclear?

Reviews note that the price point is sometimes mentioned for Avène products on this page. Azclear features only one product on this page, and no pricing details are available for either brand.

### Which causes fewer breakouts, Avène or Azclear?

Avène and Azclear both include products for acne-prone skin, with Avène featuring multiple cleansers and [serums](https://lovi.care/skincare/sg/ingredients/serum) that have an oily acne-prone skin fit of High, while Azclear offers Medicated Lotion with a High fit for oily acne-prone skin.

### How do the founding years and parent companies of Avène and Azclear compare?

Avène was founded in 1990 in France and is owned by Fondation Pierre Fabre, whereas Azclear was founded in 2010 and is owned by Ego Pharmaceuticals.

### Which Avène products are fragrance-free, and does Azclear offer any fragrance-free products?

Avene offers 8 fragrance-free products on this page, including the Cicalfate+ Restorative Protective Cream, Tolerance Control Soothing Skin Recovery Balm, and RetrinAL EYES. Azclear also offers fragrance-free products, as every product on this page lists no fragrance in its ingredients.

### What is the Lovi fit level of Azclear Medicated Lotion for oily acne-prone skin compared to Avène's Cleanance sunscreen?

Azclear Medicated Lotion has a High Lovi fit level for oily acne-prone skin. Avène's Cleanance sunscreen also has a High Lovi fit level for oily acne-prone skin.

## Research behind their key ingredients

- [Vitamin A antagonizes decreased cell growth and elevated collagen-degrading matrix metalloproteinases and stimulates collagen accumulation in naturally aged human skin](https://pubmed.ncbi.nlm.nih.gov/10692106/) Retinol · The Journal of Investigative Dermatology, 2000
- [The effect of niacinamide on reducing cutaneous pigmentation and suppression of melanosome transfer](https://pubmed.ncbi.nlm.nih.gov/12100180/) Niacinamide · The British Journal of Dermatology, 2002
- [Mechanistic Basis and Clinical Evidence for the Applications of Nicotinamide (Niacinamide) to Control Skin Aging and Pigmentation](https://pubmed.ncbi.nlm.nih.gov/34439563/) Niacinamide · Antioxidants, 2021
- [Benefits of topical hyaluronic acid for skin quality and signs of skin aging: From literature review to clinical evidence](https://pubmed.ncbi.nlm.nih.gov/36200921/) Hyaluronic acid, Sodium hyaluronate · Dermatologic Therapy, 2022
- [Improvement of naturally aged skin with vitamin A (retinol)](https://pubmed.ncbi.nlm.nih.gov/17515510/) Retinol · Archives of Dermatology, 2007
- [Topical ascorbic acid on photoaged skin. Clinical, topographical and ultrastructural evaluation: double-blind study vs. placebo](https://pubmed.ncbi.nlm.nih.gov/12823436/) Ascorbic acid activ cg · Experimental Dermatology, 2003
- [Anti-aging and brightening effects of a topical treatment containing vitamin C, vitamin E, and raspberry leaf cell culture extract: A split-face, randomized controlled trial](https://pubmed.ncbi.nlm.nih.gov/31975502/) Tocopherol · Journal of Cosmetic Dermatology, 2020
- [Molecular basis of retinol anti-ageing properties in naturally aged human skin in vivo](https://pubmed.ncbi.nlm.nih.gov/27261203/) Retinol · International Journal of Cosmetic Science, 2017
- [Prospective, randomized, double-blind assessment of topical bakuchiol and retinol for facial photoageing](https://pubmed.ncbi.nlm.nih.gov/29947134/) Retinol, Bakuchiol · The British Journal of Dermatology, 2019
- [Efficacy and Safety of Azelaic Acid Nanocrystal-Loaded In Situ Hydrogel in the Treatment of Acne Vulgaris](https://pubmed.ncbi.nlm.nih.gov/33923739/) Azelaic acid · Pharmaceutics, 2021
- [The 24-hour skin hydration and barrier function effects of a hyaluronic 1%, glycerin 5%, and Centella asiatica stem cells extract moisturizing fluid: an intra-subject, randomized, assessor-blinded study](https://pubmed.ncbi.nlm.nih.gov/28860834/) Glycerin · Clinical, Cosmetic and Investigational Dermatology, 2017
- [Randomized controlled study for the anti-aging effect of human adipocyte-derived mesenchymal stem cell media combined with niacinamide after laser therapy](https://pubmed.ncbi.nlm.nih.gov/33103316/) Niacinamide · Journal of Cosmetic Dermatology, 2021
- [Senomorphic activity of a combination of niacinamide and hyaluronic acid: correlation with clinical improvement of skin aging](https://pubmed.ncbi.nlm.nih.gov/39009698/) Niacinamide · Scientific Reports, 2024
- [Efficacy and tolerability assessment of a topical formulation containing copper sulfate and hypericum perforatum on patients with herpes skin lesions: a comparative, randomized controlled trial](https://pubmed.ncbi.nlm.nih.gov/22270204/) Copper sulfate · Journal of Drugs in Dermatology, 2012
- [Adenosine-loaded dissolving microneedle patches to improve skin wrinkles, dermal density, elasticity and hydration](https://pubmed.ncbi.nlm.nih.gov/29574973/) Adenosine · International Journal of Cosmetic Science, 2018
- [Biomimetic hyaluronic acid-stabilized zinc oxide nanoparticles in acne treatment: A preclinical and clinical approach](https://pubmed.ncbi.nlm.nih.gov/40254135/) Zinc oxide · Journal of Controlled Release, 2025
- [An oil-soluble extract of Rubus idaeus cells enhances hydration and water homeostasis in skin cells](https://pubmed.ncbi.nlm.nih.gov/25940647/) Rubus idaeus fruit extract raspberry fruit extract · International Journal of Cosmetic Science, 2015
- [Inhibition of TRPV1 prevented skin irritancy induced by phenoxyethanol. A preliminary in vitro and in vivo study](https://pubmed.ncbi.nlm.nih.gov/27168163/) Phenoxyethanol · International Journal of Cosmetic Science, 2017
- [A dermocosmetic containing bakuchiol, Ginkgo biloba extract and mannitol improves the efficacy of adapalene in patients with acne vulgaris: result from a controlled randomized trial](https://pubmed.ncbi.nlm.nih.gov/25914553/) Bakuchiol · Clinical, Cosmetic and Investigational Dermatology, 2015
- [Effects of 15% Azelaic Acid Gel in the Management of Post-Inflammatory Erythema and Post-Inflammatory Hyperpigmentation in Acne Vulgaris](https://pubmed.ncbi.nlm.nih.gov/38734843/) Azelaic acid · Dermatology and Therapy, 2024
- [Assessment of the Benefit of a Deep Cleansing Gel Containing Salicylic Acid 2%, Zinc Gluconate 0.2% and Lipohydroxy Acids 0.05% in Patients with Mild to Moderate Truncal Acne: Results from an Exploratory Study](https://pubmed.ncbi.nlm.nih.gov/36698447/) Zinc gluconate · Clinical, Cosmetic and Investigational Dermatology, 2023
- [A new dermocosmetic containing retinaldehyde, delta-tocopherol glucoside and glycylglycine oleamide for managing naturally aged skin: results from in vitro to clinical studies](https://pubmed.ncbi.nlm.nih.gov/28203099/) Tocopheryl glucoside · Clinical, Cosmetic and Investigational Dermatology, 2017
- [Efficacy and safety of non-thermal nitrogen plasma versus long-pulsed Nd:YAG laser for hand rejuvenation](https://pubmed.ncbi.nlm.nih.gov/33420853/) Nitrogen · Lasers in Medical Science, 2022
- [Clinical evaluation of the efficacy of a facial serum containing dioic acid, glycolic acid, salicylic acid, LHA, citric acid, and HEPES in treating post-inflammatory hyperchromia and controlling oily skin in patients with acne vulgaris](https://pubmed.ncbi.nlm.nih.gov/33617668/) Citric acid · Journal of Cosmetic Dermatology, 2021
- [The usefulness of a dermocosmetic containing Myrtus communis extract and azelaic acid for maintenance phase of adult female acne: Results from a randomized exploratory investigator-blinded comparative study](https://pubmed.ncbi.nlm.nih.gov/36729399/) Azelaic acid · Journal of the European Academy of Dermatology and Venereology, 2023
- [Comparative benefit of two thermal spring waters after photodynamic therapy procedure](https://pubmed.ncbi.nlm.nih.gov/17348993/) Avène thermal spring water, Avene thermal spring water avene aqua · Journal of Cosmetic Dermatology, 2007
- [Wax-oil lubricants to reduce the shear between skin and PPE](https://pubmed.ncbi.nlm.nih.gov/34078980/) Paraffinum liquidum mineral oil · Scientific Reports, 2021
- [Two-phase delivery using a horse oil and adenosine-loaded dissolving microneedle patch for skin barrier restoration, moisturization, and wrinkle improvement](https://pubmed.ncbi.nlm.nih.gov/30160014/) Adenosine · Journal of Cosmetic Dermatology, 2019
- [Comparison of methods for assessing photoprotection against ultraviolet A in vivo](https://pubmed.ncbi.nlm.nih.gov/3819071/) Butyl methoxydibenzoylmethane · Journal of the American Academy of Dermatology, 1987
- [Using ordered mesoporous silica SBA-15 to limit cutaneous penetration and transdermal permeation of organic UV filters](https://pubmed.ncbi.nlm.nih.gov/31437563/) Butyl methoxydibenzoylmethane · International Journal of Pharmaceutics, 2019
- [Topical Zinc Oxide Nanoparticle Formulations for Acne Vulgaris: A Systematic Review of Pre-Clinical and Early-Phase Clinical Evidence](https://pubmed.ncbi.nlm.nih.gov/41007718/) Zinc oxide · Biomedicines, 2025
- [Influence of vitamin E acetate on stratum corneum hydration](https://pubmed.ncbi.nlm.nih.gov/9706379/) Tocopheryl acetate · Arzneimittel-Forschung, 1998
- [Specific protection of sensitive skin against environmental stress by maintenance and improvement of barrier function](https://pubmed.ncbi.nlm.nih.gov/35315151/) Aquaphilus dolomiae extract filtrate · Journal of the European Academy of Dermatology and Venereology, 2022
- [TiO2-embedded mesoporous silica with lower porosity is beneficial to adsorb the pollutants and retard UV filter absorption: A possible application for outdoor skin protection](https://pubmed.ncbi.nlm.nih.gov/36455708/) Butyl methoxydibenzoylmethane · European Journal of Pharmaceutical Sciences, 2023
- [Effect of an Emollient Emulsion Containing 15.0% of Caprylic/Capric Triglyceride on the Urocanic Acid of the Stratum Corneum](https://pubmed.ncbi.nlm.nih.gov/37109405/) Caprylic capric triglyceride · Life, 2023
- [Sustained effect of two antioxidants (oxothiazolidine and δ-tocopheryl glucoside) for immediate and long-term sun protection in a sunscreen emulsion based on their different penetrating properties](https://pubmed.ncbi.nlm.nih.gov/33848378/) Tocopheryl glucoside · International Journal of Cosmetic Science, 2021
- [Comparison of clindamycin 1% and benzoyl peroxide 5% gel to a novel composition containing salicylic acid, capryloyl salicylic acid, HEPES, glycolic acid, citric acid, and dioic acid in the treatment of acne vulgaris](https://pubmed.ncbi.nlm.nih.gov/23545907/) Citric acid · Journal of Drugs in Dermatology, 2013
- [Nanostructured Lipid Carrier Based Gel Containing α-Tocopherol and α-Tocopheryl Acetate for Synergistic Cutaneous Antiaging Efficacy](https://pubmed.ncbi.nlm.nih.gov/41309687/) Tocopheryl acetate · Scientific Reports, 2025
- [Clinical evaluation of anaesthetic-like effect of two dermocosmetic formulations containing Aquaphilus dolomiae extract-G3 in subjects with sensitive facial skin](https://pubmed.ncbi.nlm.nih.gov/35315150/) Aquaphilus dolomiae extract filtrate · Journal of the European Academy of Dermatology and Venereology, 2022
- [The Real-World Effectiveness and Tolerability of a Soothing Cream Containing the Postbiotic Aquaphilus dolomiae Extract-G2 for Skin Healing](https://pubmed.ncbi.nlm.nih.gov/38451421/) Aquaphilus dolomiae extract filtrate · Dermatology and Therapy, 2024
- [A Double-Blind, 12-Week Study to Evaluate the Antiaging Efficacy of a Cream Containing the NFκB Inhibitor 4-Hexyl-1, 3-Phenylenediol and Ascorbic Acid-2 Glucoside in Adult Females](https://pubmed.ncbi.nlm.nih.gov/27272084/) Ascorbyl glucoside · Journal of Drugs in Dermatology, 2016
- [Protective properties of Avène Thermal Spring Water on biomechanical, ultrastructural and clinical parameters of human skin](https://pubmed.ncbi.nlm.nih.gov/32870553/) Thermal spring water, Aqua dolomiae extract · Journal of the European Academy of Dermatology and Venereology, 2020
- [Effects of Malaysian thermal spring water as adjunct therapy for mild to moderate acne vulgaris - a prospective, randomised, controlled, split face study](https://pubmed.ncbi.nlm.nih.gov/38553920/) Avène thermal spring water, Avene thermal spring water avene aqua, Thermal spring water · The Medical Journal of Malaysia, 2024
- [Rapid and Visible Efficacy of a Dermocosmetic in Acne Patients With Fair Skin Phototypes: Results of a Randomized Split-Face Study](https://pubmed.ncbi.nlm.nih.gov/41487026/) Zinc gluconate · Journal of Cosmetic Dermatology, 2026
- [Safety assessment on comedogenicity of dermatological products containing d-alpha tocopheryl acetate in Asian subjects: A double-blind randomized controlled trial](https://pubmed.ncbi.nlm.nih.gov/34471722/) Tocopheryl acetate · Contemporary Clinical Trials Communications, 2021
- [A cleanser formulated with Tris (hydroxymethyl) aminomethane and l-arginine significantly improves facial acne in male Thai subjects](https://pubmed.ncbi.nlm.nih.gov/31347768/) Arginine · Journal of Cosmetic Dermatology, 2020
- [Treatment with Ascorbyl Glucoside-Arginine Complex Ameliorates Solar Lentigos](https://pubmed.ncbi.nlm.nih.gov/39769217/) Ascorbyl glucoside · International Journal of Molecular Sciences, 2024
- [A Randomized Controlled Trial of the Genistein Plus Bakuchiol and Vitamins (GEN+) Product for Male Facial Skin: Effects on Skin Appearance and Properties](https://pubmed.ncbi.nlm.nih.gov/41562471/) Bakuchiol · Skin Research and Technology, 2026
- [Retrospective Review of Dermal Safety Studies of Organic Sunscreens](https://pubmed.ncbi.nlm.nih.gov/40911743/) Ethylhexyl salicylate · Journal of Drugs in Dermatology, 2025
- [Efficacy and safety of combination cream of stimu-tex AS™ (spent grain wax, Argania Spinosa Kernel oil, Butyrospermum Parkii (shea butter) extract), and saccharide isomerate after fractional CO2 laser procedure: split-face, double blinded, randomized controlled trial](https://pubmed.ncbi.nlm.nih.gov/41134387/) Butyrospermum parkii butter shea butter · Lasers in Medical Science, 2025
- [Clinical Evaluation of a Soap-Free Cleansing Lotion Containing Sodium Cocoyl Apple Amino Acids for Effective Impurity Removal and Skin Barrier Preservation in Healthy Adults With Diverse Skin Types](https://pubmed.ncbi.nlm.nih.gov/40978887/) Cetyl alcohol · Cureus, 2025
- [Dermatological Effects of a Beeswax-Pine Resin Mixture on Abdominal Skin: A Proof-of-Concept Study Supporting the Development of an Affordable Investigational Ostomy Pouching System in Low-Income Regions](https://pubmed.ncbi.nlm.nih.gov/42758164/) Beeswax cera alba cera · Journal of Wound, Ostomy, and Continence Nursing, 2026
- [Prospective, Randomized, Double-Blind Assessment of Supramolecular Bakuchiol and Terminalia Chebula Extract for Facial Photoaging in Chinese Sensitive Skin Population](https://pubmed.ncbi.nlm.nih.gov/41424674/) Bakuchiol · Health Science Reports, 2025

## The brands

- French skincare: [Avène](https://lovi.care/skincare/sg/brands/avene)
- Skincare: [Azclear](https://lovi.care/skincare/sg/brands/azclear)

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## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this comparison: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

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