# Anessa vs NEOCUTIS

Page: https://lovi.care/skincare/sg/compare/anessa-vs-neocutis

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Singapore.

Anessa and NEOCUTIS are skincare brands that offer thoughtfully crafted formulas to nurture the complexion. The Japanese brand founded in 1992 is widely loved for its advanced sunscreens and sophisticated formulas, suiting all skin types best with options like the Perfect UV Sunscreen Skincare Milk and Perfect UV Sunscreen Skincare Gel. Conversely, the Swiss brand founded in 2003 is widely beloved for its refined [serums](https://lovi.care/skincare/sg/ingredients/serum) and moisturizers, suiting mature, dry, and stressed skin best through deeply restorative properties like Bio Serum Firm and lumière. These two lines differ primarily because one focuses on reliable daily protection for all complexions, while the other delivers balanced, gentle care to restore natural radiance.

Anessa is a Japanese skincare brand founded in 1992 and owned by Shiseido Company, Limited.

[anessaco.com](https://anessaco.com/about/) [en.wikipedia.org](https://en.wikipedia.org/wiki/Shiseido) [corp.shiseido.com](https://corp.shiseido.com/en/company/talk/20240625.html) [happi.com](https://www.happi.com/top-company-profile/shiseido/)

NEOCUTIS is a Swiss skincare brand founded in 2003 and owned by Merz Holding GmbH & Co. KG since 2013.

[businesswire.com](https://www.businesswire.com/news/home/20260716926041/en/Merz-Completes-Inaugural-%E2%82%AC450-Million-Schuldschein-Loan-Issuance) [gcimagazine.com](https://www.gcimagazine.com/brands-products/skin-care/news/21870673/merz-to-purchase-neocutis)

This page compares some of the most popular Anessa and NEOCUTIS products; for every product of both brands, with a fit score for your own skin, [use the Lovi app](https://app.pora.ai/vqqJ/j1xj2b6o?af_sub2=compare&af_sub3=selection_note&af_sub4=pgf38f98a7ca).

### Popular Anessa vs NEOCUTIS products

#### Anessa

- [Perfect UV Sunscreen Skincare Milk](https://lovi.care/skincare/sg/p/anessa/perfect-uv-sunscreen-skincare-milk/for/oily-skin) — High fit — [S$22.09 at YesStyle](https://www.yesstyle.com/en/shiseido-anessa-perfect-uv-sunscreen-skincare-milk-spf-50-pa-2024/info.html/pid.1127278830?curr=SGD&rco=SG)
- [Perfect UV Sunscreen Skincare Gel](https://lovi.care/skincare/sg/p/anessa/perfect-uv-sunscreen-skincare-gel/for/sensitive-skin) — High fit

#### NEOCUTIS

- [Bio Serum Firm](https://lovi.care/skincare/sg/p/neocutis/bio-serum-firm/for/mature-skin) — High fit
- [lumière](https://lovi.care/skincare/sg/p/neocutis/lumiere/for/dry-skin) — Average fit

## Questions and answers

### Anessa or NEOCUTIS: which is better?

Anessa earns High Lovi fit ratings across many skin types for its sunscreens on this page, while NEOCUTIS varies from High to Average for its anti-aging [serum](https://lovi.care/skincare/sg/ingredients/serum) and moisturizer. Every product from both brands on this page lists no fragrance in its ingredients.

### What is the difference between Anessa and NEOCUTIS?

Anessa is a Japanese sunscreen brand founded in 1992, while NEOCUTIS is a Swiss skincare brand founded in 2003. Both brands offer fragrance-free products on this page, but Anessa focuses on sunscreens with high fits for oily and acne-prone skin, whereas NEOCUTIS features anti-aging and moisturizing products like Bio Serum Firm.

### Which is more affordable, Anessa or NEOCUTIS?

The provided page facts do not mention the prices of products from either Anessa or NEOCUTIS, so it is not possible to determine which brand is more affordable.

### Which causes fewer breakouts, Anessa or NEOCUTIS?

Anessa has a High Lovi fit for acne-prone skin with the products on this page, while NEOCUTIS only has an Average fit. Every product from both brands lists no fragrance in its ingredients.

### Which brand is older, Anessa or NEOCUTIS?

Anessa is older than NEOCUTIS because Anessa was founded in Japan in 1992, while NEOCUTIS was founded in Switzerland in 2003.

### Where were Anessa and NEOCUTIS originally founded?

Anessa was originally founded in Japan, while NEOCUTIS was originally founded in Switzerland.

### Do Anessa and NEOCUTIS products contain fragrance?

Every product from Anessa and NEOCUTIS on this page lists no fragrance in its ingredients.

## Research behind their key ingredients

- [Benefits of topical hyaluronic acid for skin quality and signs of skin aging: From literature review to clinical evidence](https://pubmed.ncbi.nlm.nih.gov/36200921/) Hyaluronic acid · Dermatologic Therapy, 2022
- [Collagen Supplements for Aging and Wrinkles: A Paradigm Shift in the Fields of Dermatology and Cosmetics](https://pubmed.ncbi.nlm.nih.gov/35223163/) Water-soluble collagen · Dermatology Practical & Conceptual, 2022
- [Skin penetration and stabilization of formulations containing microfine titanium dioxide as physical UV filter](https://pubmed.ncbi.nlm.nih.gov/18503414/) Titanium dioxide · International Journal of Cosmetic Science, 2000
- [Vitamin C-squalene bioconjugate promotes epidermal thickening and collagen production in human skin](https://pubmed.ncbi.nlm.nih.gov/33037252/) Squalane · Scientific Reports, 2020
- [Treatment of acne with a combination of propolis, tea tree oil, and Aloe vera compared to erythromycin cream: two double-blind investigations](https://pubmed.ncbi.nlm.nih.gov/30588129/) Aloe barbadensis leaf extract · Clinical Pharmacology, 2018
- [Use of Collagen in Cosmetic Products](https://pubmed.ncbi.nlm.nih.gov/38534748/) Water-soluble collagen · Current Issues in Molecular Biology, 2024
- [Injectable thermo-sensitive and wide-crack self-healing hydrogel loaded with antibacterial anti-inflammatory dipotassium glycyrrhizate for full-thickness skin wound repair](https://pubmed.ncbi.nlm.nih.gov/35245682/) Dipotassium glycyrrhizate · Acta Biomaterialia, 2022
- [Green tea extract reduces induction of p53 and apoptosis in UVB-irradiated human skin independent of transcriptional controls](https://pubmed.ncbi.nlm.nih.gov/18631247/) Camellia sinensis leaf extract · Experimental Dermatology, 2009
- [The 24-hour skin hydration and barrier function effects of a hyaluronic 1%, glycerin 5%, and Centella asiatica stem cells extract moisturizing fluid: an intra-subject, randomized, assessor-blinded study](https://pubmed.ncbi.nlm.nih.gov/28860834/) Glycerin · Clinical, Cosmetic and Investigational Dermatology, 2017
- [The human stratum corneum layer: an effective barrier against dermal uptake of different forms of topically applied micronised titanium dioxide](https://pubmed.ncbi.nlm.nih.gov/11509913/) Titanium dioxide · Skin Pharmacology and Applied Skin Physiology, 2001
- [Biomimetic hyaluronic acid-stabilized zinc oxide nanoparticles in acne treatment: A preclinical and clinical approach](https://pubmed.ncbi.nlm.nih.gov/40254135/) Zinc oxide · Journal of Controlled Release, 2025
- [Evaluation of dermal extracellular matrix and epidermal-dermal junction modifications using matrix-assisted laser desorption/ionization mass spectrometric imaging, in vivo reflectance confocal microscopy, echography, and histology: effect of age and peptide applications](https://pubmed.ncbi.nlm.nih.gov/25817264/) Palmitoyl tripeptide-1 acetate, Palmitoyl tetrapeptide-7 · Journal of Cosmetic Dermatology, 2015
- [Antiacne and antiblotch activities of a formulated combination of Aloe barbadensis leaf powder, Garcinia mangostana peel extract, and Camellia sinensis leaf extract](https://pubmed.ncbi.nlm.nih.gov/31239743/) Camellia sinensis leaf extract · Clinical, Cosmetic and Investigational Dermatology, 2019
- [In vivo and in vitro evaluation of octyl methoxycinnamate liposomes](https://pubmed.ncbi.nlm.nih.gov/24376350/) Ethylhexyl methoxycinnamate · International Journal of Nanomedicine, 2013
- [Squalane as a Promising Agent Protecting UV-Induced Inhibition of Collagen Biosynthesis and Wound Healing in Human Dermal Fibroblast](https://pubmed.ncbi.nlm.nih.gov/40363772/) Squalane · Molecules, 2025
- [Topical Zinc Oxide Nanoparticle Formulations for Acne Vulgaris: A Systematic Review of Pre-Clinical and Early-Phase Clinical Evidence](https://pubmed.ncbi.nlm.nih.gov/41007718/) Zinc oxide · Biomedicines, 2025
- [Influence of vitamin E acetate on stratum corneum hydration](https://pubmed.ncbi.nlm.nih.gov/9706379/) Tocopheryl acetate · Arzneimittel-Forschung, 1998
- [Nanostructured Lipid Carrier Based Gel Containing α-Tocopherol and α-Tocopheryl Acetate for Synergistic Cutaneous Antiaging Efficacy](https://pubmed.ncbi.nlm.nih.gov/41309687/) Tocopheryl acetate · Scientific Reports, 2025
- [Facial disbiosis and UV filters](https://pubmed.ncbi.nlm.nih.gov/39499337/) Ethylhexyl methoxycinnamate · Archives of Dermatological Research, 2024
- [Mitigation of ultraviolet-induced erythema and inflammation by para-hydroxycinnamic acid in human skin](https://pubmed.ncbi.nlm.nih.gov/39138602/) Ethylhexyl methoxycinnamate · International Journal of Cosmetic Science, 2025
- [Efficacy of a Topical Formulation on Skin Hydration and Barrier Function in Individuals With Xerosis: A 28-Day Randomized, Split-Leg, Untreated-Controlled Trial](https://pubmed.ncbi.nlm.nih.gov/42108609/) Dipotassium glycyrrhizate · Journal of Cosmetic Dermatology, 2026
- [Targeting Circadian Rhythm for the Regulation of Skin Collagen Metabolism](https://pubmed.ncbi.nlm.nih.gov/41527525/) Palmitoyl tripeptide-1 acetate, Palmitoyl tripeptide-1 · Journal of Cosmetic Dermatology, 2026
- [Mechanistic understanding and peptide ingredient screening for type III collagen via biological knowledge graph and molecular docking](https://pubmed.ncbi.nlm.nih.gov/42683869/) Palmitoyl tripeptide-1 acetate · International Journal of Cosmetic Science, 2026

## The brands

- Japanese skincare: [Anessa](https://lovi.care/skincare/sg/brands/anessa)
- Swiss skincare: [NEOCUTIS](https://lovi.care/skincare/sg/brands/neocutis)

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## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this comparison: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

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- Singapore: https://lovi.care/skincare/sg/compare/anessa-vs-neocutis (this page)
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