# ZO Skin Health Daily Power Defense for dry skin

**Lovi Fit: Average fit for dry skin.**
Dry Skin Fit: High · Effectiveness: Average · Safety: High.

Page: https://lovi.care/skincare/sa/p/zo-skin-health/daily-power-defense/for/dry-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Saudi Arabia.

Brand: [ZO Skin Health](https://lovi.care/skincare/sa/brands/zo-skin-health)
Category: [Serums and treatments](https://lovi.care/skincare/sa/best/serums)

This fit is calculated for the concerns frequently associated with dry skin: flakiness, tightness, dehydration, fine lines, and wrinkles. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for dry skin; other serums fit it better.

## Why this fit

- Offers moderate hydration and barrier support for your dry skin, as glycerin and Safflower Palm Aminopropanediol Esters Oil provide humectant and emollient actions. Micrococcus lysate and tocopherol offer excellent antioxidant protection and barrier enhancement.
- The product provides general skincare benefits, such as cleansing and soothing, which are supportive for your dry or flaky skin.
- The safety profile is excellent, with no risks of irritation for your dry skin due to the absence of prohibited or harsh ingredients.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/sa/p/zo-skin-health/daily-power-defense/for/oily-skin): High
- [Dry skin](https://lovi.care/skincare/sa/p/zo-skin-health/daily-power-defense/for/dry-skin): Average (this page)
- [Combination skin](https://lovi.care/skincare/sa/p/zo-skin-health/daily-power-defense/for/combination-skin): Average
- [Sensitive skin](https://lovi.care/skincare/sa/p/zo-skin-health/daily-power-defense/for/sensitive-skin): Average
- [Acne-prone skin](https://lovi.care/skincare/sa/p/zo-skin-health/daily-power-defense/for/acne-prone-skin): High
- [Skin with dark spots](https://lovi.care/skincare/sa/p/zo-skin-health/daily-power-defense/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/sa/p/zo-skin-health/daily-power-defense/for/mature-skin): Average
- [Dry sensitive skin](https://lovi.care/skincare/sa/p/zo-skin-health/daily-power-defense/for/dry-sensitive-skin): Average
- [Oily acne-prone skin](https://lovi.care/skincare/sa/p/zo-skin-health/daily-power-defense/for/oily-acne-prone-skin): Average

## Key ingredients

Retinol, Beta-Glucan, Arabidopsis Thaliana Extract, Tocopheryl Acetate, Palmitoyl Tripeptide-1

## What the research says

- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Vitamin E in O/W and W/O emulsions significantly increased stratum corneum hydration and enhanced water-binding capacity, with an optimum concentration of 5%. ([Arzneimittel-Forschung, 1998](https://pubmed.ncbi.nlm.nih.gov/9706379/))
- Skin care regimens containing beta-glucan improved hemoglobin index, skin hydration, and transepidermal water loss compared to vehicle control in 20 patients undergoing fractional laser therapy. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33128496/))
- Dermatological products containing d-alpha tocopheryl acetate showed non-comedogenic potential with less than a 50% increase in microcomedones in 12 healthy male subjects compared to octyl palmitate. ([Contemporary Clinical Trials Communications, 2021](https://pubmed.ncbi.nlm.nih.gov/34471722/))
- Topical 0.4% retinol significantly increased epidermal thickness, dermal vascularity, and extracellular matrix production by stimulating keratinocyte proliferation, endothelial cell proliferation, and fibroblast activation in naturally aged human skin compared to vehicle. ([International Journal of Cosmetic Science, 2017](https://pubmed.ncbi.nlm.nih.gov/27261203/))
- Topical bakuchiol 0.5% applied twice daily compared with retinol 0.5% applied daily significantly decreased wrinkle surface area and hyperpigmentation with no statistical difference between the compounds in 44 patients over 12 weeks, while retinol users reported more facial skin scaling and stinging. ([The British Journal of Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/29947134/))
- Silicone particles encapsulating retinol increased its half-life by 9-fold and yielded 12-23% lower skin irritation in human subjects compared to Microsponge particles while maintaining biological activity. ([Journal of Controlled Release, 2018](https://pubmed.ncbi.nlm.nih.gov/29604311/))
- Treatment with topical formulations containing beta-glucan combined with nanofractional radiofrequency plus magnetic nanofractional radiofrequency showed the best efficacy and was tolerable and effective in Chinese women with abdominal stretch marks compared to control groups. ([Dermatology and Therapy, 2023](https://pubmed.ncbi.nlm.nih.gov/37171578/))
- Topical beta-glucan mildly improved striae gravidarum, 1565-nm non-ablative fractional laser showed better results than topical beta-glucan, and the combined strategy further improved striae gravidarum atrophy compared to single treatment. ([The Journal of Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/35570397/))
- Topical application of oat beta-glucan ameliorates epidermal hyperplasia and accelerates epidermal barrier recovery by promoting keratinocyte differentiation through dectin-1-mediated ERK and p38 signaling pathways that upregulate CaSR expression. ([International Journal of Biological Macromolecules, 2021](https://pubmed.ncbi.nlm.nih.gov/34237364/))
- Topical application of an antioxidant serum containing 15% ascorbic acid, 0.5% ferulic acid, and 1% tocopherol prevented particulate matter-induced degradation of extracellular matrix components, inflammation, and oxidative stress in the skin of 15 female volunteers compared to untreated controls. ([Journal of Cosmetic Dermatology, 2025](https://pubmed.ncbi.nlm.nih.gov/40642809/))
- Topical application of an antioxidant mix containing 15% ascorbic acid, 0.5% ferulic acid, and 1% tocopherol prevented PM and UV-induced skin barrier perturbation, lipid peroxidation, inflammatory markers, MMP9 activation, and Type I collagen loss in 15 healthy females compared to untreated exposed skin. ([Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38590207/))
- A topical antioxidant serum significantly reduced air pollution-induced skin pigmentation and proinflammatory gene expression ex vivo, and improved skin aging signs in 40 healthy adult females after 90 days of daily use. ([Journal of Cosmetic Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/35150043/))
- A multi-modal methodology combining MALDI-MSI, in vivo RCM, echography, and histology revealed age-related decreases in extracellular matrix and epidermal-dermal junction proteins and undulation depth, while a blend of palmitoyl oligopeptide and palmitoyl tetrapeptide-7 improved subepidermal low-echogenic band thickness, density, and extracellular matrix structure compared to placebo. ([Journal of Cosmetic Dermatology, 2015](https://pubmed.ncbi.nlm.nih.gov/25817264/))
- Chronomodulated daytime application of baicalin and nighttime application of palmitoyl tripeptide-1 synergistically improved skin luminance by 16.29%, nasolabial fold depth by -36.35%, and firmness by 24.35% in 30 female participants. ([Journal of Cosmetic Dermatology, 2026](https://pubmed.ncbi.nlm.nih.gov/41527525/))
- Palmitoyl tetrapeptide-7, acetyl hexapeptide-8, palmitoyl tripeptide-1, and palmitoyl tetrapeptide-10 significantly increased type III collagen levels in human dermal fibroblasts following UV exposure, with their combination demonstrating a greater effect in vitro and enhancing type I, III, and IV collagen levels in ex vivo skin tissues compared to individual components. ([International Journal of Cosmetic Science, 2026](https://pubmed.ncbi.nlm.nih.gov/42683869/))

## What reviewers say

Based on limited data, this serum is highly regarded for its ability to repair the skin barrier, providing a healthy glow and improved texture. Most users appreciate its lightweight feel and hydrating properties. Some users report experiencing initial irritation or breakouts due to active ingredients, and the high price point is a frequent concern.

- Liked: Barrier repair (mostly mentioned)
- Liked: Lightweight & absorbent (often mentioned)
- Disliked: High price point (often mentioned)
- Liked: Anti-aging results (sometimes noted)
- Liked: Versatile hydration (sometimes noted)
- Disliked: Initial irritation (sometimes noted)
- Disliked: Counterfeit risk (rarely noted)
- Disliked: Scent/packaging (rarely noted)

## How to apply

- Apply this serum PM, starting 3×/week and working up to daily use as your skin adjusts.
- Place the serum after cleansing and toner, but right before your moisturizer.
- Gently press 2-3 drops of the serum into your skin and let it absorb for a minute.
- Apply the serum on slightly damp skin to help lock in extra moisture.
- Avoid the eye area and do a patch test before your first use.
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### How well does Daily Power Defense work for dry skin?

ZO Skin Health Daily Power Defense works moderately well for dry skin, offering helpful moisture and antioxidant protection without irritation. To fit dry skin even better, a treatment of this type needs richer hydrating ingredients, ceramides, niacinamide, and soothing plant extracts for deep nourishment and barrier support.
Sources: [Arzneimittel-Forschung, 1998](https://pubmed.ncbi.nlm.nih.gov/9706379/)

### Which ingredients make this serum a good fit for dry skin?

Glycerin, safflower palm aminopropanediol esters oil, and beta-glucan help make this serum a good fit by offering moisture and barrier support for dry skin. To work best for dry skin, a product of this type needs richer hydrating ingredients like ceramides, niacinamide, and propolis to deeply nourish and maintain a healthy glow.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### What does Retinol do for dry skin?

Retinol is a poor fit for dry skin because it frequently causes scaling, stinging, and dryness. To care for dry skin properly, a product needs gentle, hydrating ingredients like ceramides, glycerin, and hyaluronic acid to lock in moisture and keep the skin barrier calm and smooth.
Sources: [The British Journal of Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/29947134/), [Journal of Drugs in Dermatology, 2023](https://pubmed.ncbi.nlm.nih.gov/37276158/)

### What does Beta-Glucan do for dry skin?

Beta-glucan helps dry skin by boosting hydration and supporting the skin barrier so it holds onto moisture better. Studies show that using beta-glucan daily improves skin moisture and helps calm dryness and roughness.
Sources: [International Journal of Cosmetic Science, 2008](https://pubmed.ncbi.nlm.nih.gov/19099547/), [Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33128496/)

### Where does this serum go in a skincare routine for dry skin?

This treatment goes in the evening routine after cleansing and before your moisturizer. Dry skin needs a rich moisturizer and a gentle hydrating toner to keep it soft and comfortable.

### Can I use it with vitamin C, and in what order?

You can use this treatment with vitamin C by applying vitamin C first on clean, dry skin, followed by this product. Because this treatment offers only moderate hydration and barrier support, dry skin needs an extra rich moisturizer and heavy oils to deeply lock in moisture.
Sources: [Arzneimittel-Forschung, 1998](https://pubmed.ncbi.nlm.nih.gov/9706379/)

### How often should I use this serum?

This treatment is used in the evening in your routine, starting once a week and gradually increasing as your skin adjusts. To work best for dry skin, this product needs richer moisturizing ingredients and barrier-supporting oils that deeply soften and stop moisture loss.

### Can it clog pores, cause breakouts or purging for dry skin?

This treatment is unlikely to clog pores or cause breakouts for dry skin, and it has a very safe profile with no harsh ingredients. However, because it contains retinol, it may occasionally cause mild initial irritation as your skin gets used to it.

### Is this serum fragrance-free and alcohol-free?

It has no drying alcohol and contains fragrance (parfum and limonene). Cetearyl alcohol is a fatty alcohol, which soften the skin.

## Alternatives for dry skin

- [Beauty of Joseon Propolis + Niacinamide Glow Serum](https://lovi.care/skincare/sa/p/beauty-of-joseon/propolis-niacinamide-glow-serum/for/dry-skin) — Superior fit — SAR 226.83 at Amazon
- [Paula's Choice RESIST Super Antioxidant Concentrate Serum](https://lovi.care/skincare/sa/p/paula-s-choice/resist-super-antioxidant-concentrate-serum/for/dry-skin) — Superior fit — SAR 461.00 at Amazon
- [ma:nyo Bifida Biome Complex Ampoule](https://lovi.care/skincare/sa/p/ma-nyo/bifida-biome-complex-ampoule/for/dry-skin) — Superior fit — SAR 145.51 at Amazon

## Pairs well with

- Cleanser: [La Roche-Posay Hydrating Gentle Cleanser](https://lovi.care/skincare/sa/p/la-roche-posay/toleriane-hydrating-gentle-cleanser/for/dry-skin) — Superior fit — SAR 297.00 at Amazon
- Moisturizer: [SKIN1004 Madagascar Centella Probio-Cica Enrich Cream](https://lovi.care/skincare/sa/p/skin1004/madagascar-centella-probio-cica-enrich-cream/for/dry-skin) — Superior fit — SAR 48.00 at Amazon
- SPF: [d'Alba Piedmont Waterfull Mild Sunscreen](https://lovi.care/skincare/sa/p/d-alba/piedmont-waterfull-mild-sunscreen/for/dry-skin) — Superior fit — SAR 75.00 at Amazon

## Where to buy

- Amazon.sa: SAR 662.61 (https://www.amazon.sa/dp/B07QF1B66M?tag=lovisa02-21&linkCode=osi&th=1&psc=1)
Prices checked 4 Nov 2026.

## Ingredients

Water, 1,2-Hexanediol, Dicaprylyl Carbonate, Cetearyl Isononanoate, Glycerin, Pentylene Glycol, Cetearyl Alcohol, Steareth-20, Safflower Palm Aminopropanediol Esters Oil, Laminaria Digitata Extract, Opuntia Ficus-Indica Stem Extract, Arabidopsis Thaliana Extract, Marrubium Vulgare Meristem Cell Culture, Leontopodium Alpinum Meristem Cell Culture, Retinyl Palmitate, Tocopheryl Acetate, Tocopherol, Micrococcus Lysate, Caprylyl Glycol, Hexylene Glycol, Lactose, Galactoarabinan, Schizophyllan, Beta-Glucan, Carbomer, Cellulose, Maltodextrin, C14-22 Alcohols, C12-20 Alkyl Glucoside, Hydroxypropyl Methylcellulose, Disodium Edta, Sodium Hydroxide, Phenoxyethanol, Ethylhexylglycerin, Sodium Benzoate, Parfum, Ultramarines, Limonene
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/zo-skin-health/daily-power-defense/for/dry-skin
- United Kingdom: https://lovi.care/skincare/uk/p/zo-skin-health/daily-power-defense/for/dry-skin
- Ireland: https://lovi.care/skincare/ie/p/zo-skin-health/daily-power-defense/for/dry-skin
- Germany: https://lovi.care/skincare/de/p/zo-skin-health/daily-power-defense/for/dry-skin
- France: https://lovi.care/skincare/fr/p/zo-skin-health/daily-power-defense/for/dry-skin
- Italy: https://lovi.care/skincare/it/p/zo-skin-health/daily-power-defense/for/dry-skin
- Netherlands: https://lovi.care/skincare/nl/p/zo-skin-health/daily-power-defense/for/dry-skin
- Spain: https://lovi.care/skincare/es/p/zo-skin-health/daily-power-defense/for/dry-skin
- Canada: https://lovi.care/skincare/ca/p/zo-skin-health/daily-power-defense/for/dry-skin
- Australia: https://lovi.care/skincare/au/p/zo-skin-health/daily-power-defense/for/dry-skin
- Singapore: https://lovi.care/skincare/sg/p/zo-skin-health/daily-power-defense/for/dry-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/zo-skin-health/daily-power-defense/for/dry-skin (this page)
- United Arab Emirates: https://lovi.care/skincare/ae/p/zo-skin-health/daily-power-defense/for/dry-skin