# The INKEY List 10% Azelaic Acid Serum for mature skin

**Lovi Fit: High fit for mature skin.**
Normal Skin Fit: High · Effectiveness: Average · Safety: High.

Page: https://lovi.care/skincare/sa/p/the-inkey-list/10-azelaic-acid-serum/for/mature-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Saudi Arabia.

Brand: [The INKEY List](https://lovi.care/skincare/sa/brands/the-inkey-list)
Category: [Serums and treatments](https://lovi.care/skincare/sa/best/serums)

This fit is calculated for the concerns frequently associated with mature skin: fine lines, wrinkles, and loss of firmness. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

A great choice for mature skin; a few serums fit it even better.

## Why this fit

- Highly suitable for your normal skin, this serum contains azelaic acid and glycerin to help regulate melanogenesis and provide humectant action, offering supportive benefits for wrinkles and fine lines through mild exfoliation and antioxidant effects.
- The moderate concentration of azelaic acid also aids in reducing acne lesions, further supporting your skin's overall health.
- The safety profile is excellent, with no risks of irritation due to the absence of prohibited or harsh ingredients.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/sa/p/the-inkey-list/10-azelaic-acid-serum/for/oily-skin): High
- [Dry skin](https://lovi.care/skincare/sa/p/the-inkey-list/10-azelaic-acid-serum/for/dry-skin): High
- [Combination skin](https://lovi.care/skincare/sa/p/the-inkey-list/10-azelaic-acid-serum/for/combination-skin): Superior
- [Sensitive skin](https://lovi.care/skincare/sa/p/the-inkey-list/10-azelaic-acid-serum/for/sensitive-skin): High
- [Acne-prone skin](https://lovi.care/skincare/sa/p/the-inkey-list/10-azelaic-acid-serum/for/acne-prone-skin): Superior
- [Skin with dark spots](https://lovi.care/skincare/sa/p/the-inkey-list/10-azelaic-acid-serum/for/dark-spots): High
- [Mature skin](https://lovi.care/skincare/sa/p/the-inkey-list/10-azelaic-acid-serum/for/mature-skin): High (this page)
- [Dry sensitive skin](https://lovi.care/skincare/sa/p/the-inkey-list/10-azelaic-acid-serum/for/dry-sensitive-skin): High
- [Oily acne-prone skin](https://lovi.care/skincare/sa/p/the-inkey-list/10-azelaic-acid-serum/for/oily-acne-prone-skin): High

## Key ingredients

Azelaic Acid, Allantoin, Glycerin, Hydrolyzed Gardenia Florida Extract, Niacinamide

## What the research says

- Application of 15% azelaic acid gel significantly reduced post-inflammatory erythema and hyperpigmentation, decreased hemoglobin and melanin content, improved quality of life, and contributed to acne improvement in patients with mild to moderate acne compared to placebo. ([Dermatology and Therapy, 2024](https://pubmed.ncbi.nlm.nih.gov/38734843/))
- Azelaic acid nanocrystal hydrogel 10% achieved a higher success rate and greater lesion reduction than azelaic acid cream 20% in patients with mild to moderate facial acne. ([Pharmaceutics, 2021](https://pubmed.ncbi.nlm.nih.gov/33923739/))
- Topical treatment of nicotinamide, alone or in combination with other active ingredients, reduces the progression of skin aging and hyperpigmentation in clinical trials while being well tolerated. ([Antioxidants, 2021](https://pubmed.ncbi.nlm.nih.gov/34439563/))
- Topical application of a dermocosmetic containing Myrtus communis extract and azelaic acid reduced acne relapses and helped maintain remission compared to a light moisturizing cream in adult females in the acne maintenance phase over 16 weeks. ([Journal of the European Academy of Dermatology and Venereology, 2023](https://pubmed.ncbi.nlm.nih.gov/36729399/))
- Topical administration of 20% azelaic acid cream and 5% tranexamic acid solution comparably improved acne-related postinflammatory hyperpigmentation in patients with acne vulgaris, while tranexamic acid demonstrated a significantly better safety profile at week 4. ([Journal of Research in Medical Sciences, 2023](https://pubmed.ncbi.nlm.nih.gov/37213446/))
- Azelaic acid 15% gel showed comparable efficacy to adapalene 0.1% gel in reducing lesions, severity, and Dermatology Life Quality Index in women with adult acne, with significantly lower dryness and scaling, and demonstrated superiority during maintenance compared to no further treatment. ([Journal of the European Academy of Dermatology and Venereology, 2015](https://pubmed.ncbi.nlm.nih.gov/25399481/))
- Topical gel containing chitosan, 0.2% chlorhexidine, allantoin and dexpanthenol did not improve postoperative comfort regarding swelling and pain, but improved the wound's aesthetic appearance following impacted lower third molar extraction compared to no gel. ([Medicina Oral, Patologia Oral Y Cirugia Bucal, 2016](https://pubmed.ncbi.nlm.nih.gov/27475700/))
- A topical gel containing chitosan, chlorhexidine, allantoin, and dexpanthenol significantly reduced postoperative pain, trismus, swelling, and analgesic consumption, while improving wound healing after third molar surgery compared to a placebo. ([Medicina Oral, Patologia Oral Y Cirugia Bucal, 2020](https://pubmed.ncbi.nlm.nih.gov/32683390/))
- An overnight patch containing Allium cepa extract and allantoin safely promotes scar healing after dermatologic surgery, resulting in significantly greater reductions in observer- and patient-assessed POSAS scores compared to no treatment. ([Aesthetic Plastic Surgery, 2018](https://pubmed.ncbi.nlm.nih.gov/29948103/))
- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- The emollient V0034CR significantly reduced TEWL compared to vehicle and vehicle plus glycerol, and significantly increased corneometry scores compared to vehicle and vehicle plus petrolatum in healthy volunteers with dry skin, demonstrating combined barrier function improvement from petrolatum and hydration improvement from glycerol. ([Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31532576/))
- Ten days of treatment with a cream containing 20% glycerin significantly increased skin hydration measured by corneometer values in 17 healthy volunteers compared to a placebo cream, but showed no influence on transepidermal water loss or skin sensitivity to an irritating surfactant. ([International Journal of Cosmetic Science, 2001](https://pubmed.ncbi.nlm.nih.gov/18498456/))
- Gardenia jasminoides extract protected against blue light digital stress and premature aging with a decrease in wrinkle number by -21% compared to placebo. ([International Journal of Molecular Sciences, 2023](https://pubmed.ncbi.nlm.nih.gov/36902379/))
- Crocin exhibits antioxidant potential, protects squalene against UVA-induced peroxidation, prevents inflammatory mediator release, and modulates NF-kB-related and glycosylation-related gene expression in normal human epidermal keratinocytes and human dermal fibroblasts in vitro. ([International Journal of Cosmetic Science, 2018](https://pubmed.ncbi.nlm.nih.gov/29893408/))
- Gardenia jasminoides extract dose-dependently enhanced cell viability, attenuated UVB-induced mRNA expressions of IL-1β and TNF-α in HaCaT keratinocytes, and indirectly inhibited MMP-1 protein expression in human dermal fibroblasts compared to UVB exposure alone. ([Evidence-based Complementary and Alternative Medicine, 2014](https://pubmed.ncbi.nlm.nih.gov/24711853/))
- Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33103316/))
- Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women. ([The Journal of Investigative Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/17882270/))
- Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging. ([Dermatologic Surgery, 2005](https://pubmed.ncbi.nlm.nih.gov/16029679/))

## What reviewers say

It also often smooths skin texture and evens tone. Some users report it can be drying, necessitating immediate moisturizer application.

- Liked: Reduces redness (mostly mentioned)
- Liked: Clears acne (often mentioned)
- Liked: Affordable and effective (sometimes noted)
- Liked: Smoothes texture (sometimes noted)
- Disliked: Drying and tight (sometimes noted)
- Disliked: Itching and tingling (rarely noted)
- Disliked: Small packaging (rarely noted)
- Disliked: Texture and pilling (rarely noted)

## How to apply

- Use this serum in your PM routine. Start by applying it 3 times a week, and work up to daily use if your skin likes it.
- Apply this serum after your toner and before your moisturizer.
- Gently press 2-3 drops of the serum into your skin and let it absorb for a minute.
- You can apply the serum on dry skin for the best results against fine lines.
- Always do a patch test before your first use and avoid the sensitive eye area.
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### What makes The INKEY List Azelaic Acid Serum a great fit for mature skin?

This serum is a great fit for mature skin because it uses azelaic acid and glycerin to help smooth fine lines, gently remove dead skin cells, and keep your face hydrated. It also has a very safe formula with no harsh ingredients, so it is unlikely to cause irritation.

### Which ingredients make this serum a good fit for mature skin?

Azelaic acid, glycerin, and niacinamide make this serum a great fit for mature skin by helping smooth fine lines, even out skin tone, and keep the skin feeling soft. These ingredients provide gentle exfoliation and moisture while supporting overall skin health without causing irritation.

### What does Azelaic Acid do for mature skin?

Azelaic acid helps mature skin by targeting dark spots and uneven tone, while supporting smoother texture and a more youthful look. It provides antioxidant benefits that may reduce signs of aging and protect skin from environmental stress.
Sources: [Frontiers in Medicine, 2026](https://pubmed.ncbi.nlm.nih.gov/42023095/), [Journal of Cosmetic Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/36056802/)

### What does Allantoin do for mature skin?

Allantoin helps soothe dry and irritated mature skin while supporting a smooth and healthy skin barrier. This ingredient may improve overall skin softness and comfort, making it a helpful addition to daily anti-aging routines.
Sources: [Pharmaceutics, 2026](https://pubmed.ncbi.nlm.nih.gov/41900878/), [Journal of Functional Biomaterials, 2021](https://pubmed.ncbi.nlm.nih.gov/34842756/)

### Where does this serum go in a skincare routine for mature skin?

This serum goes in the evening routine after cleansing and toning, followed by your moisturizer. Using it at night keeps things simple and helps avoid extra sun sensitivity.

### Can I use this serum with retinol, and in what order?

Yes, you can use this serum with retinol by applying them on alternate nights or using the retinol at night and this serum in the morning to avoid any potential dryness. This product is very safe and unlikely to cause irritation.

### How often should I use this serum?

You can use this treatment in your evening routine once a week to start, and then carefully use it more often if your skin tolerates it well and you see good results. It is unlikely to cause irritation due to the absence of harsh ingredients.

### Can this serum clog pores, cause breakouts or purging for mature skin?

This serum is unlikely to clog pores or cause breakouts for mature skin because its gentle azelaic acid and glycerin formula helps keep skin clear and calm without harsh ingredients. It also aids in reducing acne lesions and smoothing out fine lines, making it a safe choice for everyday use.
Sources: [Pharmaceutics, 2021](https://pubmed.ncbi.nlm.nih.gov/33923739/)

### Is this serum fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for mature skin

- [Paula's Choice RESIST Super Antioxidant Concentrate Serum](https://lovi.care/skincare/sa/p/paula-s-choice/resist-super-antioxidant-concentrate-serum/for/mature-skin) — Superior fit — SAR 461.00 at Amazon
- [SkinCeuticals C E Ferulic](https://lovi.care/skincare/sa/p/skinceuticals/c-e-ferulic/for/mature-skin) — Superior fit — SAR 865.37 at Amazon
- [La Prairie Skin Caviar Liquid Lift](https://lovi.care/skincare/sa/p/la-prairie/skin-caviar-liquid-lift/for/mature-skin) — High fit — SAR 5,271.00 at Amazon

## Pairs well with

- Cleanser: [Fresh Soy Face Cleanser](https://lovi.care/skincare/sa/p/fresh/soy-face-cleanser/for/mature-skin) — Superior fit — SAR 191.00 at Amazon
- Hydrating Toner: [COSRX Propolis Synergy Toner](https://lovi.care/skincare/sa/p/cosrx/full-fit-propolis-synergy-toner/for/mature-skin) — Superior fit — SAR 30.00 at Amazon
- Moisturizer: [Obagi Hydrate Luxe Moisture-Rich Cream](https://lovi.care/skincare/sa/p/obagi/hydrate-luxe/for/mature-skin) — Superior fit — SAR 329.18 at Amazon

## Where to buy

- Amazon.sa: SAR 149.00 (https://www.amazon.sa/dp/B0BJ7JKRWY?tag=lovisa02-21&linkCode=osi&th=1&psc=1)
Prices checked 6 Nov 2026.

## Ingredients

Water, Azelaic Acid, Propanediol, Hydroxyethyl Acrylate Sodium Acryloyldimethyl Taurate Copolymer, Phenoxyethanol, Acacia Senegal Gum, Xanthan Gum, Allantoin, Glycerin, Ethylhexylglycerin, Polysorbate 60, Sorbitan Isostearate, Maltodextrin, Sodium Hydroxide, Hydrolyzed Gardenia Florida Extract, Gardenia Florida Fruit Extract, Polylysine
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/the-inkey-list/10-azelaic-acid-serum/for/mature-skin
- United Kingdom: https://lovi.care/skincare/uk/p/the-inkey-list/10-azelaic-acid-serum/for/mature-skin
- Ireland: https://lovi.care/skincare/ie/p/the-inkey-list/10-azelaic-acid-serum/for/mature-skin
- Germany: https://lovi.care/skincare/de/p/the-inkey-list/10-azelaic-acid-serum/for/mature-skin
- France: https://lovi.care/skincare/fr/p/the-inkey-list/10-azelaic-acid-serum/for/mature-skin
- Italy: https://lovi.care/skincare/it/p/the-inkey-list/10-azelaic-acid-serum/for/mature-skin
- Netherlands: https://lovi.care/skincare/nl/p/the-inkey-list/10-azelaic-acid-serum/for/mature-skin
- Spain: https://lovi.care/skincare/es/p/the-inkey-list/10-azelaic-acid-serum/for/mature-skin
- Canada: https://lovi.care/skincare/ca/p/the-inkey-list/10-azelaic-acid-serum/for/mature-skin
- Australia: https://lovi.care/skincare/au/p/the-inkey-list/10-azelaic-acid-serum/for/mature-skin
- Singapore: https://lovi.care/skincare/sg/p/the-inkey-list/10-azelaic-acid-serum/for/mature-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/the-inkey-list/10-azelaic-acid-serum/for/mature-skin (this page)
- United Arab Emirates: https://lovi.care/skincare/ae/p/the-inkey-list/10-azelaic-acid-serum/for/mature-skin