# The History of Whoo Bichup Self-Generating Anti-Aging Concentrate for mature skin

**Lovi Fit: High fit for mature skin.**
Normal Skin Fit: High · Effectiveness: High · Safety: High.

Page: https://lovi.care/skincare/sa/p/the-history-of-whoo/bichup-self-generating-anti-aging-concentrate/for/mature-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Saudi Arabia.

Brand: The History of Whoo
Category: [Serums and treatments](https://lovi.care/skincare/sa/best/serums)

This fit is calculated for the concerns frequently associated with mature skin: fine lines, wrinkles, and loss of firmness. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

A great choice for mature skin; a few serums fit it even better.

## Why this fit

- Excellent for your normal skin, this formula features acetyl hexapeptide-8 and copper tripeptide-1 to effectively minimize fine lines and wrinkles by promoting collagen synthesis and skin elasticity.
- Glycerin and biosaccharide gum-1 provide essential hydration, while ceramides and cholesterol support your skin barrier, ensuring overall skin health and comfort.
- The product is safe for your skin, with no risks of irritation due to the absence of prohibited or harsh ingredients.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/sa/p/the-history-of-whoo/bichup-self-generating-anti-aging-concentrate/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/sa/p/the-history-of-whoo/bichup-self-generating-anti-aging-concentrate/for/dry-skin): High
- [Combination skin](https://lovi.care/skincare/sa/p/the-history-of-whoo/bichup-self-generating-anti-aging-concentrate/for/combination-skin): Average
- [Sensitive skin](https://lovi.care/skincare/sa/p/the-history-of-whoo/bichup-self-generating-anti-aging-concentrate/for/sensitive-skin): High
- [Acne-prone skin](https://lovi.care/skincare/sa/p/the-history-of-whoo/bichup-self-generating-anti-aging-concentrate/for/acne-prone-skin): Average
- [Skin with dark spots](https://lovi.care/skincare/sa/p/the-history-of-whoo/bichup-self-generating-anti-aging-concentrate/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/sa/p/the-history-of-whoo/bichup-self-generating-anti-aging-concentrate/for/mature-skin): High (this page)
- [Dry sensitive skin](https://lovi.care/skincare/sa/p/the-history-of-whoo/bichup-self-generating-anti-aging-concentrate/for/dry-sensitive-skin): High
- [Oily acne-prone skin](https://lovi.care/skincare/sa/p/the-history-of-whoo/bichup-self-generating-anti-aging-concentrate/for/oily-acne-prone-skin): Average

## Key ingredients

Niacinamide, Ceramide Np, Panax Ginseng Root Extract, Copper Tripeptide-1, Hydrolyzed Soy Protein

## What the research says

- Argireline treatment twice daily for 4 weeks produced a significant anti-wrinkle effect with 48.9% total efficacy and decreased skin roughness in Chinese subjects compared with 0% efficacy and no decrease in roughness in the placebo group. ([American Journal of Clinical Dermatology, 2013](https://pubmed.ncbi.nlm.nih.gov/23417317/))
- Argireline applied twice daily for 4 weeks achieved a total anti-wrinkle efficiency of 48.9% and notably reduced wrinkle depth compared to placebo in Chinese subjects. ([Journal of Cosmetic and Laser Therapy, 2013](https://pubmed.ncbi.nlm.nih.gov/23607739/))
- Treatment with cross-linked hyaluronic acid-based microneedle patches combined with acetyl hexapeptide-8 or epidermal growth factor significantly improved wrinkles and skin hydration compared to the patch alone in Korean females over 29 days. ([Annals of Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/33911590/))
- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33103316/))
- Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women. ([The Journal of Investigative Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/17882270/))
- Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging. ([Dermatologic Surgery, 2005](https://pubmed.ncbi.nlm.nih.gov/16029679/))
- Enzyme-modified ginseng extract cream significantly reduced the global photo-damage score and various roughness measures including total roughness, smoothness depth, and arithmetic roughness average compared to placebo in 23 human subjects. ([Rejuvenation Research, 2015](https://pubmed.ncbi.nlm.nih.gov/25867599/))
- A red ginseng hydrogel formulation with 1,2-hexanediol promoted selective growth of Staphylococcus epidermidis and decreased Cutibacterium acnes in 20 female subjects. ([Journal of Ginseng Research, 2022](https://pubmed.ncbi.nlm.nih.gov/35509819/))
- A 1% fermented black ginseng cream significantly reduced eye wrinkles and brightened skin color in twenty-three human subjects compared to control cream and baseline. ([Journal of Toxicology and Environmental Health. Part A, 2020](https://pubmed.ncbi.nlm.nih.gov/32564709/))
- Topical copper tripeptide complex on CO2 laser-resurfaced skin caused no significant reduction in erythema or objective improvement in wrinkles compared to controls, but significantly increased patient satisfaction regarding overall skin quality. ([Archives of Facial Plastic Surgery, 2006](https://pubmed.ncbi.nlm.nih.gov/16847171/))
- A novel regimen combining a hydroxy acid-based scrub and copper tripeptide serum significantly reduced adherent scalp flaking by 61.24%, increased hair density by 12.48%, increased hair thickness by 25.36%, and improved scalp skin hydration by 76.24% in adults with mild to moderate dandruff over 15 days. ([Cureus, 2024](https://pubmed.ncbi.nlm.nih.gov/39449909/))
- The combination of Thermus thermophilus and Bacillus subtilis mixed-culture ferment extract and copper tripeptide-1 GHK-Cu reduced inflammatory cytokines, protected skin explants from UV-induced damage, and improved wrinkles and skin barrier conditions compared to individual components or controls. ([Skin Research and Technology, 2026](https://pubmed.ncbi.nlm.nih.gov/42573538/))

## What reviewers say

Many users report plumper, firmer skin with diminished fine lines. However, some find the texture sticky and the floral fragrance overpowering.

- Liked: Deep hydration (often mentioned)
- Liked: Radiant glow (often mentioned)
- Disliked: Strong fragrance (often mentioned)
- Liked: Plumping effect (sometimes noted)
- Liked: Soothing & healing (sometimes noted)
- Disliked: High price (sometimes noted)
- Disliked: Sticky texture (sometimes noted)
- Disliked: Awkward packaging (rarely noted)

## How to apply

- Use this serum in your PM routine. Start by applying it 3 times a week, and work up to daily use if your skin likes it.
- Apply this serum after your toner and before your moisturizer.
- Gently press 2-3 drops of the serum into your skin and let it absorb for a minute.
- You can apply the serum on dry skin for the best results against fine lines.
- Always do a patch test before your first use and avoid the sensitive eye area.
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### What makes Bichup Self-Generating Anti-Aging Concentrate a great fit for mature skin?

This treatment is a great fit for mature skin because it uses acetyl hexapeptide-8 and copper tripeptide-1 to smooth fine lines and boost skin elasticity. It also provides essential hydration and supports your skin barrier with glycerin, ceramides, and cholesterol for a comfortable, healthy feel.
Sources: [American Journal of Clinical Dermatology, 2013](https://pubmed.ncbi.nlm.nih.gov/23417317/), [Journal of Cosmetic and Laser Therapy, 2013](https://pubmed.ncbi.nlm.nih.gov/23607739/)

### Which ingredients make this serum a good fit for mature skin?

This serum is a great fit for mature skin because it contains acetyl hexapeptide-8 and copper tripeptide-1, which help smooth out fine lines and wrinkles.
Sources: [American Journal of Clinical Dermatology, 2013](https://pubmed.ncbi.nlm.nih.gov/23417317/), [Journal of Cosmetic and Laser Therapy, 2013](https://pubmed.ncbi.nlm.nih.gov/23607739/)

### What does Niacinamide do for mature skin?

Niacinamide helps mature skin by smoothing out fine lines and wrinkles, reducing dark spots, and improving overall skin elasticity. It is also very well tolerated and supports a strong skin barrier to keep skin looking healthy.
Sources: [Antioxidants, 2021](https://pubmed.ncbi.nlm.nih.gov/34439563/), [Journal of Cosmetic Dermatology, 2004](https://pubmed.ncbi.nlm.nih.gov/17147561/)

### What do Ceramides do for mature skin?

Ceramides help keep mature skin feeling soft and smooth by strengthening the moisture barrier and locking in hydration. This type of skin needs ingredients that rebuild lost moisture and protect against dryness to stay comfortable.
Sources: [Experimental Dermatology, 2025](https://pubmed.ncbi.nlm.nih.gov/39912256/), [American Journal of Clinical Dermatology, 2003](https://pubmed.ncbi.nlm.nih.gov/12553851/)

### Where does this serum go in a skincare routine for mature skin?

This treatment goes in the evening routine after cleansing and before moisturizing, as Lovi routines place treatments in the evening for simplicity and extra safety around sun exposure.

### Can I use this serum with retinol, and in what order?

You can use this treatment alongside retinol by applying the serum first to give your skin essential hydration and barrier support, followed by your retinol. This product is unlikely to cause irritation because it lacks harsh ingredients, helping to keep your skin comfortable.

### How often should I use this serum?

This serum fits your mature skin very well and is used in the evening as part of your routine. Nonprescription topical treatments like this one serve as a low-risk mainstay for skin rejuvenation.
Sources: [Facial Plastic Surgery, 2014](https://pubmed.ncbi.nlm.nih.gov/24488631/), [American Journal of Clinical Dermatology, 2013](https://pubmed.ncbi.nlm.nih.gov/23417317/)

### Can this serum clog pores, cause breakouts or purging for mature skin?

This treatment is unlikely to clog pores or cause breakouts for mature skin. It features nourishing ingredients and a safe profile that helps keep skin comfortable without harsh additives.

### Is this serum fragrance-free and alcohol-free?

It has no drying alcohol and contains fragrance (benzyl salicylate, citronellol, geraniol, limonene, and linalool).

## Alternatives for mature skin

- [Paula's Choice RESIST Super Antioxidant Concentrate Serum](https://lovi.care/skincare/sa/p/paula-s-choice/resist-super-antioxidant-concentrate-serum/for/mature-skin) — Superior fit — SAR 461.00 at Amazon
- [SkinCeuticals C E Ferulic](https://lovi.care/skincare/sa/p/skinceuticals/c-e-ferulic/for/mature-skin) — Superior fit — SAR 865.37 at Amazon
- [La Prairie Skin Caviar Liquid Lift](https://lovi.care/skincare/sa/p/la-prairie/skin-caviar-liquid-lift/for/mature-skin) — High fit — SAR 5,271.00 at Amazon

## Pairs well with

- Cleanser: [Fresh Soy Face Cleanser](https://lovi.care/skincare/sa/p/fresh/soy-face-cleanser/for/mature-skin) — Superior fit — SAR 191.00 at Amazon
- Hydrating Toner: [COSRX Propolis Synergy Toner](https://lovi.care/skincare/sa/p/cosrx/full-fit-propolis-synergy-toner/for/mature-skin) — Superior fit — SAR 30.00 at Amazon
- Moisturizer: [Obagi Hydrate Luxe Moisture-Rich Cream](https://lovi.care/skincare/sa/p/obagi/hydrate-luxe/for/mature-skin) — Superior fit — SAR 329.18 at Amazon

## Where to buy

No store in Saudi Arabia has a checked price for this product, so the page shows none.

## Ingredients

Water, Glycerin, Dipropylene Glycol, Peg Ppg Polybutylene Glycol-8 5 3 Glycerin, Glyceryl Polymethacrylate, Biosaccharide Gum-1, Dimethicone, 1,2-Hexanediol, Peg-150, Propylene Glycol, Phenyl Trimethicone, Panthenol, Methyl Trimethicone, Cordyceps Sinensis Extract, Nelumbo Nucifera Extract, Nuphar Japonicum Root Extract, Panax Ginseng Root Extract, Ophiopogon Japonicus Root Extract, Rehmannia Chinensis Root Extract, Poria Cocos Extract, Dioscorea Japonica Root Extract, Glycyrrhiza Glabra Root Extract Licorice Root Extract, Typha Angustifolia Spike Extract, Paeonia Albiflora Extract, Scutellaria Baicalensis Root Extract, Angelica Gigas Extract, Saposhnikovia Divaricata Root Extract, Atractylodes Japonica Root Extract, Cinnamomum Cassia Bark Extract, Zingiber Officinale Root Extract, Ziziphus Jujuba Fruit Extract, Angelica Acutiloba Root Extract, Cornus Officinalis Fruit Extract, Velvet Extract, Theobroma Cacao Extract, Thymus Vulgaris Extract, Hydroxyproline, Ceramide Np, Cholesterol, Arbutin, Oligopeptide-1, Oligopeptide-2, Oligopeptide-4, Hydrolyzed Soy Protein, Acetyl Hexapeptide-8, Copper Tripeptide-1, Arginine, Cystine, Histidine Hcl, Isoleucine, Leucine, Lysine, Methionine, Phenylalanine, Threonine, Tryptophan, Tyrosine, Valine, Biotin, Folic Acid, Inositol, Niacinamide, Calcium Pantothenate, Pyridoxine Hcl, Riboflavin, Thiamine Hcl, Cyanocobalamin, Glycosphingolipids, Beta-Glucan, Hydrogenated Lecithin, Peg-10 Rapeseed Sterol, Glyceryl Stearate, Glycereth-20, C14-22 Alcohols, Phytosqualane, Macadamia Ternifolia Seed Oil, Triethylhexanoin, Arachidyl Glucoside, Butyrospermum Parkii Butter Shea Butter, Stearic Acid, Peg-100 Stearate, Polymethylsilsesquioxane, Cyclopentasiloxane, Dimethiconol, Butylene Glycol, Peg-60 Hydrogenated Castor Oil, Carbomer, Algin, Sodium Polyacrylate, Acrylates C10-30 Alkyl Acrylate Crosspolymer, Sunset Yellow Fcf, Tartrazine, Tromethamine, Trisodium Edta, Alpha-Isomethyl Ionone, Benzyl Salicylate, Citronellol, Geraniol, Hydroxycitronellal, Limonene, Linalool
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/the-history-of-whoo/bichup-self-generating-anti-aging-concentrate/for/mature-skin
- United Kingdom: https://lovi.care/skincare/uk/p/the-history-of-whoo/bichup-self-generating-anti-aging-concentrate/for/mature-skin
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- Australia: https://lovi.care/skincare/au/p/the-history-of-whoo/bichup-self-generating-anti-aging-concentrate/for/mature-skin
- Singapore: https://lovi.care/skincare/sg/p/the-history-of-whoo/bichup-self-generating-anti-aging-concentrate/for/mature-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/the-history-of-whoo/bichup-self-generating-anti-aging-concentrate/for/mature-skin (this page)
- United Arab Emirates: https://lovi.care/skincare/ae/p/the-history-of-whoo/bichup-self-generating-anti-aging-concentrate/for/mature-skin