# SkinCeuticals Phloretin CF for acne-prone skin

**Lovi Fit: High fit for acne-prone skin.**
Combination Skin Fit: High · Effectiveness: High · Safety: High.

Page: https://lovi.care/skincare/sa/p/skinceuticals/phloretin-cf/for/acne-prone-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Saudi Arabia.

Brand: [SkinCeuticals](https://lovi.care/skincare/sa/brands/skinceuticals)
Category: [Serums and treatments](https://lovi.care/skincare/sa/best/serums)

This fit is calculated for the concerns frequently associated with acne-prone skin: breakouts, blackheads, and post-acne marks. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

A great choice for acne-prone skin; a few serums fit it even better.

## Why this fit

- This formulation offers excellent antioxidant protection and helps to even skin tone for your combination skin, as ascorbic acid and ferulic acid work synergistically to shield from environmental stressors and support collagen synthesis.
- The presence of phloretin further enhances the benefits for your acne, blemishes, and breakouts by providing additional antioxidant protection and improving overall skin tone.
- The safety profile is excellent, with no risks of irritation due to the absence of prohibited or harsh ingredients.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/sa/p/skinceuticals/phloretin-cf/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/sa/p/skinceuticals/phloretin-cf/for/dry-skin): Caution
- [Combination skin](https://lovi.care/skincare/sa/p/skinceuticals/phloretin-cf/for/combination-skin): High
- [Sensitive skin](https://lovi.care/skincare/sa/p/skinceuticals/phloretin-cf/for/sensitive-skin): Average
- [Acne-prone skin](https://lovi.care/skincare/sa/p/skinceuticals/phloretin-cf/for/acne-prone-skin): High (this page)
- [Skin with dark spots](https://lovi.care/skincare/sa/p/skinceuticals/phloretin-cf/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/sa/p/skinceuticals/phloretin-cf/for/mature-skin): Average
- [Dry sensitive skin](https://lovi.care/skincare/sa/p/skinceuticals/phloretin-cf/for/dry-sensitive-skin): Low
- [Oily acne-prone skin](https://lovi.care/skincare/sa/p/skinceuticals/phloretin-cf/for/oily-acne-prone-skin): High

## Key ingredients

Phloretin, Ascorbic Acid, Ferulic Acid

## What the research says

- A topical antioxidant solution of 15% L-ascorbic acid, 1% alpha-tocopherol, and 0.5% ferulic acid provides significant photoprotection against solar-simulated UV radiation in human skin compared to its vehicle. ([Journal of the American Academy of Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/18603326/))
- Pretreatment with a topical antioxidant mixture of vitamin C, ferulic acid, and phloretin attenuated ultraviolet-induced sunburn cell formation, thymine dimer formation, matrix metalloproteinase-9 expression, p53 protein expression, and the suppression of CD1a-expressing Langerhans cells in human skin compared to vehicle control. ([Journal of Cosmetic Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/19146606/))
- Phloretin inhibits the growth of acne-related bacteria, attenuates P. acnes-induced inflammatory mediators in vitro, and significantly reduces comedo counts, sebum output, and porphyrin levels in subjects with whiteheads compared to before treatment. ([International Journal of Cosmetic Science, 2016](https://pubmed.ncbi.nlm.nih.gov/26212527/))
- Phloretin 3',3-disulfonate attenuated UVB-induced cyclobutane pyrimidine dimer formation, glutathione depletion, apoptosis, and inflammatory mediator release in skin cells by enhancing nucleotide excision repair gene expression. ([International Journal of Molecular Sciences, 2014](https://pubmed.ncbi.nlm.nih.gov/25334063/))
- Compound 11c showed potent inhibitory activity against tyrosinase at nanomolar concentrations and reduced melanin content in a UV-induced skin pigmentation guinea pig model. ([Journal of Medicinal Chemistry, 2023](https://pubmed.ncbi.nlm.nih.gov/36940414/))
- An optimized phloretin-based antiacne hydrogel formulation achieved 75% drug release over 120 minutes and strong antimicrobial activity against Staphylococcus epidermidis with an 11 mm inhibition zone, comparable to benzoyl peroxide gel, while showing no skin irritancy. ([Anti-inflammatory & Anti-allergy Agents in Medicinal Chemistry, 2026](https://pubmed.ncbi.nlm.nih.gov/42163615/))
- Topical application of 5% vitamin C cream significantly improved global clinical scores, increased skin microrelief density, and induced elastic tissue repair in photoaged skin compared to excipient control in healthy female volunteers. ([Experimental Dermatology, 2003](https://pubmed.ncbi.nlm.nih.gov/12823436/))
- Ascorbic acid 2-glucoside gel significantly reduced gingival melanin pigmentation after 4 weeks compared to placebo in 73 subjects with symmetric pigmentation. ([Journal of Periodontology, 2009](https://pubmed.ncbi.nlm.nih.gov/19186973/))
- Topical application of VC-IP cream twice daily for 8 weeks reduces periorbital wrinkles in female subjects compared to a placebo cream. ([Journal of Cosmetic Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/34910367/))
- Treatment with 14% ferulic acid and 12% l-ascorbic acid significantly reduced pigmentation and erythema while improving hydration and elasticity in 20 women with photoaged skin, with neither acid proving definitively more effective overall though ascorbic acid showed slightly greater skin lightening. ([Dermatologic Therapy, 2022](https://pubmed.ncbi.nlm.nih.gov/34877760/))
- Combining fractional microneedle radiofrequency with a topical antioxidant serum significantly reduced wrinkle severity by 29.9% versus 18.0%, increased elasticity by 12.9% versus 2.3%, and improved aesthetic outcomes in 31 participants compared to radiofrequency and placebo. ([The Journal of Dermatological Treatment, 2025](https://pubmed.ncbi.nlm.nih.gov/40464749/))
- Topical ferulic acid-containing formulations effectively reduce skin erythema, hyperpigmentation, and signs of aging in adults compared to baseline or alternative conditions. ([The Journal of Clinical and Aesthetic Dermatology, 2025](https://pubmed.ncbi.nlm.nih.gov/40538529/))

## What reviewers say

Based on a very large amount of data, this product is highly regarded for brightening the complexion, evening skin tone, and reducing discoloration such as dark spots and melasma, particularly benefiting those with normal, oily, combination, or acne-prone skin. Many users report achieving smoother, more radiant skin and a decrease in fine lines. However, a significant number of reviews mention the high cost, a strong scent, and occasional issues with stickiness or packaging.

- Liked: Brightens skin (mostly mentioned)
- Liked: Fades discoloration (often mentioned)
- Liked: Lightweight texture (often mentioned)
- Disliked: High price point (often mentioned)
- Liked: Good for oily skin (sometimes noted)
- Disliked: Unpleasant scent (sometimes noted)
- Disliked: Packaging issues (rarely noted)

## How to apply

- Use your serum as part of your PM routine and start 3x/week before working up to daily use.
- Apply this treatment after cleansing and toner, and before your moisturizer.
- Gently press 2-3 drops of the serum into your skin and let it absorb for a minute.
- Apply the product on clean, dry skin to help manage your breakouts safely.
- Avoid the eye area and do a patch test before your first use.
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### What makes SkinCeuticals Phloretin CF a great fit for acne-prone skin?

SkinCeuticals Phloretin CF is a great fit for acne-prone skin because phloretin, ascorbic acid, and ferulic acid provide powerful antioxidant protection while helping to calm breakouts and even out skin tone. This product is very safe and is unlikely to cause irritation.
Sources: [Journal of Cosmetic Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/19146606/), [International Journal of Cosmetic Science, 2016](https://pubmed.ncbi.nlm.nih.gov/26212527/)

### Which ingredients make this serum a good fit for acne-prone skin?

Phloretin, Ascorbic Acid, and Ferulic Acid make this serum a great fit for your skin by providing powerful antioxidant protection and improving overall skin tone. Phloretin helps manage breakouts by calming the skin, while the other ingredients work together to shield you from environmental damage and support a smooth, even look with a very low risk of irritation.
Sources: [Journal of the American Academy of Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/18603326/), [Journal of Cosmetic Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/19146606/)

### What does phloretin do for acne-prone skin?

Phloretin helps acne-prone skin by slowing down the growth of acne-causing bacteria and reducing swelling. It also may lower oil production and decrease clogged pores to keep your skin clearer and calmer.
Sources: [International Journal of Cosmetic Science, 2016](https://pubmed.ncbi.nlm.nih.gov/26212527/), [International Journal of Molecular Sciences, 2014](https://pubmed.ncbi.nlm.nih.gov/25334063/)

### What does vitamin C do for acne-prone skin?

Vitamin C helps brighten skin and smooth out uneven texture for acne-prone skin while improving overall radiance. It also supports treatments for post-acne dark spots and aging.
Sources: [Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31975502/), [Journal of Cosmetic Dermatology, 2023](https://pubmed.ncbi.nlm.nih.gov/37128827/)

### Where does this serum go in a skincare routine for acne-prone skin?

This treatment goes in the evening routine after cleansing and before moisturizing, as Lovi routines place treatments in the PM for simplicity and extra safety around sun exposure. The formula contains Ascorbic Acid, Phloretin, and Ferulic Acid, which help protect acne-prone skin from environmental stressors and improve skin tone without causing irritation.
Sources: [Journal of Drugs in Dermatology, 2023](https://pubmed.ncbi.nlm.nih.gov/36607762/)

### Can I use this serum with retinol, and in what order?

You can use this serum alongside retinol by applying the serum in your morning routine and your retinol in the evening. This approach lets you get the protective benefits of the antioxidants while keeping your skin calm and avoiding harsh irritation.
Sources: [Journal of the American Academy of Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/18603326/), [Journal of Cosmetic Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/19146606/)

### How often should I use this serum?

This serum is a great fit for your acne-prone skin, so you can safely use it in the evening as part of your routine. Antioxidant treatments like this are well-tolerated and help shield your skin from environmental stressors while evening out skin tone.
Sources: [Journal of the American Academy of Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/18603326/), [Journal of Cosmetic Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/19146606/)

### Can this serum clog pores, cause breakouts or purging for acne-prone skin?

This serum is a great fit and is unlikely to cause breakouts or clog pores on acne-prone skin. It has a very safe formula without harsh ingredients, and phloretin helps reduce blemishes, excess oil, and acne-causing bacteria.
Sources: [International Journal of Cosmetic Science, 2016](https://pubmed.ncbi.nlm.nih.gov/26212527/), [Journal of Cosmetic Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/19146606/)

### Is this serum fragrance-free and alcohol-free?

It has no fragrance and contains drying alcohol (alcohol denat).

## Alternatives for acne-prone skin

- [Beauty of Joseon Propolis + Niacinamide Glow Serum](https://lovi.care/skincare/sa/p/beauty-of-joseon/propolis-niacinamide-glow-serum/for/acne-prone-skin) — Superior fit — SAR 226.83 at Amazon
- [SkinCeuticals C E Ferulic](https://lovi.care/skincare/sa/p/skinceuticals/c-e-ferulic/for/acne-prone-skin) — Superior fit — SAR 865.37 at Amazon
- [Clinique Fresh Pressed Daily Booster with Pure Vitamin C 10%](https://lovi.care/skincare/sa/p/clinique/fresh-pressed-daily-booster-with-pure-vitamin-c-10/for/acne-prone-skin) — Superior fit — SAR 653.00 at Amazon

## Pairs well with

- Cleanser: [CeraVe Foaming Facial Cleanser](https://lovi.care/skincare/sa/p/cerave/foaming-facial-cleanser/for/acne-prone-skin) — Superior fit — SAR 36.33 at Amazon
- Hydrating Toner: [SOME BY MI Snail Truecica Miracle Repair Toner](https://lovi.care/skincare/sa/p/some-by-mi/snail-truecica-miracle-repair-toner/for/acne-prone-skin) — Superior fit — SAR 53.04 at Amazon
- Moisturizer: [Some By Mi Yuja Niacin Brightening Moisture Gel Cream](https://lovi.care/skincare/sa/p/some-by-mi/yuja-niacin-brightening-moisture-gel-cream/for/acne-prone-skin) — Superior fit — SAR 78.95 at Amazon

## Where to buy

- Amazon.sa: SAR 602.05 (https://www.amazon.sa/dp/B0H228X6CQ?tag=lovisa02-21&linkCode=osi&th=1&psc=1)
Prices checked 6 Nov 2026.

## Ingredients

Water, Dipropylene Glycol, Alcohol Denat, Ascorbic Acid, Butylene Glycol, Triethyl Citrate, Phloretin, Ferulic Acid
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/skinceuticals/phloretin-cf/for/acne-prone-skin
- United Kingdom: https://lovi.care/skincare/uk/p/skinceuticals/phloretin-cf/for/acne-prone-skin
- Ireland: https://lovi.care/skincare/ie/p/skinceuticals/phloretin-cf/for/acne-prone-skin
- Germany: https://lovi.care/skincare/de/p/skinceuticals/phloretin-cf/for/acne-prone-skin
- France: https://lovi.care/skincare/fr/p/skinceuticals/phloretin-cf/for/acne-prone-skin
- Italy: https://lovi.care/skincare/it/p/skinceuticals/phloretin-cf/for/acne-prone-skin
- Netherlands: https://lovi.care/skincare/nl/p/skinceuticals/phloretin-cf/for/acne-prone-skin
- Spain: https://lovi.care/skincare/es/p/skinceuticals/phloretin-cf/for/acne-prone-skin
- Canada: https://lovi.care/skincare/ca/p/skinceuticals/phloretin-cf/for/acne-prone-skin
- Australia: https://lovi.care/skincare/au/p/skinceuticals/phloretin-cf/for/acne-prone-skin
- Singapore: https://lovi.care/skincare/sg/p/skinceuticals/phloretin-cf/for/acne-prone-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/skinceuticals/phloretin-cf/for/acne-prone-skin (this page)
- United Arab Emirates: https://lovi.care/skincare/ae/p/skinceuticals/phloretin-cf/for/acne-prone-skin