# SKIN1004 Madagascar Centella Hyalu-Cica First Ampoule for oily acne-prone skin

**Lovi Fit: High fit for oily acne-prone skin.**
Oily Skin Fit: High · Effectiveness: Superior · Safety: High.

Page: https://lovi.care/skincare/sa/p/skin1004/madagascar-centella-hyalu-cica-first-ampoule/for/oily-acne-prone-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Saudi Arabia.

Brand: [SKIN1004](https://lovi.care/skincare/sa/brands/skin1004)
Category: [Moisturizers and moisturizing serums](https://lovi.care/skincare/sa/best/moisturizers)

This fit is calculated for the concerns frequently associated with oily acne-prone skin: shine, breakouts, blemishes, and enlarged pores. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

A great choice for oily acne-prone skin; a few moisturizers fit it even better.

## Why this fit

- Excellent for your oily skin and acne concerns, as Centella Asiatica Extract and Niacinamide work synergistically to soothe inflammation and regulate sebum production. Sodium Hyaluronate and Glycerin provide deep hydration, ensuring your skin remains balanced and comfortable.
- The inclusion of Portulaca Oleracea Extract and Anastatica Hierochuntica Extract further supports skin barrier function and resilience, beneficial for managing breakouts.
- This formulation is safe for your skin, with no reported irritation risks due to the absence of harsh ingredients and the presence of soothing botanical extracts.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/sa/p/skin1004/madagascar-centella-hyalu-cica-first-ampoule/for/oily-skin): High
- [Dry skin](https://lovi.care/skincare/sa/p/skin1004/madagascar-centella-hyalu-cica-first-ampoule/for/dry-skin): Superior
- [Combination skin](https://lovi.care/skincare/sa/p/skin1004/madagascar-centella-hyalu-cica-first-ampoule/for/combination-skin): Average
- [Sensitive skin](https://lovi.care/skincare/sa/p/skin1004/madagascar-centella-hyalu-cica-first-ampoule/for/sensitive-skin): Superior
- [Acne-prone skin](https://lovi.care/skincare/sa/p/skin1004/madagascar-centella-hyalu-cica-first-ampoule/for/acne-prone-skin): Superior
- [Skin with dark spots](https://lovi.care/skincare/sa/p/skin1004/madagascar-centella-hyalu-cica-first-ampoule/for/dark-spots): High
- [Mature skin](https://lovi.care/skincare/sa/p/skin1004/madagascar-centella-hyalu-cica-first-ampoule/for/mature-skin): High
- [Dry sensitive skin](https://lovi.care/skincare/sa/p/skin1004/madagascar-centella-hyalu-cica-first-ampoule/for/dry-sensitive-skin): Superior
- [Oily acne-prone skin](https://lovi.care/skincare/sa/p/skin1004/madagascar-centella-hyalu-cica-first-ampoule/for/oily-acne-prone-skin): High (this page)

## Key ingredients

Centella Asiatica, Sodium Hyaluronate, Niacinamide, Glycerin, Curcuma Longa Extract

## What the research says

- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Cosmetic formulations containing 5% Centella asiatica extract showed the best efficacy in improving skin moisture and decreasing transepidermal water loss, while also exhibiting antiinflammatory properties in 25 volunteers compared to baseline measurements. ([Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/))
- Facial masks containing low-temperature extracted Portulaca oleracea protect sensitive skin from photothermal stimulation and improve skin barrier function during photorejuvenation. ([Cutaneous and Ocular Toxicology, 2025](https://pubmed.ncbi.nlm.nih.gov/41182319/))
- Co-delivery of paeonol and madecassoside via nanoemulsions improved transdermal delivery, promoted barrier repair proteins, inhibited inflammatory cytokine secretion in cellular and 3D models, and reduced transepidermal water loss and acne in human facial skin compared to free components. ([Molecules, 2023](https://pubmed.ncbi.nlm.nih.gov/37446936/))
- Topical application of 0.05% w/w ECa 233 gel reduced erythema index by 0.03 U and improved early crusting and general wound appearance compared to placebo in thirty individuals undergoing facial laser resurfacing. ([Journal of Alternative and Complementary Medicine, 2020](https://pubmed.ncbi.nlm.nih.gov/32310680/))
- Moisturizer containing 5% panthenol, madecassoside, and copper-zinc-manganese decreased adverse reactions and downtime after ablative fractional carbon dioxide laser resurfacing with comparable efficacy to 0.02% triamcinolone acetonide cream in 20 subjects. ([Journal of Cosmetic Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30945430/))
- Topical treatment with 5% vitamin C and 0.1% madecassoside significantly improved clinical scores for wrinkles, suppleness, firmness, roughness, and skin hydration, along with functional and structural remodeling of the elastic fiber network in 20 female volunteers with photoaged skin after 6 months compared to baseline. ([Experimental Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/18503551/))
- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))
- Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33103316/))
- Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women. ([The Journal of Investigative Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/17882270/))
- Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging. ([Dermatologic Surgery, 2005](https://pubmed.ncbi.nlm.nih.gov/16029679/))
- The emollient V0034CR significantly reduced TEWL compared to vehicle and vehicle plus glycerol, and significantly increased corneometry scores compared to vehicle and vehicle plus petrolatum in healthy volunteers with dry skin, demonstrating combined barrier function improvement from petrolatum and hydration improvement from glycerol. ([Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31532576/))
- Ten days of treatment with a cream containing 20% glycerin significantly increased skin hydration measured by corneometer values in 17 healthy volunteers compared to a placebo cream, but showed no influence on transepidermal water loss or skin sensitivity to an irritating surfactant. ([International Journal of Cosmetic Science, 2001](https://pubmed.ncbi.nlm.nih.gov/18498456/))
- Niacinamide/glycerin body moisturizers provided better rapid and prolonged improvement of cosmetic xerosis through functional improvement of stratum corneum barrier function compared to no treatment and conventional moisturizers in female subjects. ([Journal of Drugs in Dermatology, 2012](https://pubmed.ncbi.nlm.nih.gov/22206073/))
- Topical application of curcumin or turmeric treats various skin conditions by leveraging antioxidant, anti-inflammatory, and antimicrobial properties. ([Skin Pharmacology and Physiology, 2023](https://pubmed.ncbi.nlm.nih.gov/38008088/))
- Topical formulations of curcumin target oxidative damage and inflammation to improve wound healing in animal models. ([Drug Discovery Today, 2017](https://pubmed.ncbi.nlm.nih.gov/28711364/))
- A curcumin-loaded spanlastic anti-aging gel utilizing formula F5 incorporated into 2% HPMC E50 demonstrated sustained release action, compatibility, and the ability to penetrate skin layers to a depth of about 112.5 um without signs of irritation. ([Saudi Pharmaceutical Journal, 2024](https://pubmed.ncbi.nlm.nih.gov/38178851/))

## What reviewers say

Based on a very large amount of data, this ampoule is widely praised as a holy grail for oily, combination, and sensitive skin types due to its incredibly lightweight, water-like texture that deeply hydrates without clogging pores. While it excels at soothing redness and prepping the skin for makeup, users with very dry skin often find it insufficient as a standalone moisturizer, particularly during colder months.

- Liked: Lightweight hydration (mostly mentioned)
- Liked: Rapid absorption (mostly mentioned)
- Liked: Soothing and calming (often mentioned)
- Liked: Makeup compatibility (sometimes noted)
- Liked: Value for money (sometimes noted)
- Disliked: Insufficient for dry (sometimes noted)
- Disliked: Breakouts rare (rarely noted)
- Disliked: Lack of wow (rarely noted)
- Disliked: Runny texture (rarely noted)

## How to apply

- Use this AM and PM routine every day to help clear your skin. Always remember to finish with SPF in the morning.
- Apply the moisturizer after your cleanser and toner, right before your SPF during the day.
- Gently press a small amount into your skin and avoid rubbing to keep pores clear.
- Apply on clean, slightly damp skin to help the product absorb better and control oil.
- Avoid the sensitive eye area and do a simple patch test before your first use.
- Video: https://storage.pora.ai/2f72f5d69f07beeafc30237f829efbff.mp4

## Questions and answers

### What makes SKIN1004 Hyalu-Cica First Ampoule a great fit for oily acne-prone skin?

This product is a great fit because centella asiatica extract and niacinamide help soothe inflammation and balance oil production. Sodium hyaluronate and glycerin also provide deep hydration to keep your skin comfortable, while soothing botanical extracts support your skin barrier without irritation risks.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/), [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/)

### Which ingredients make this serum a good fit for oily acne-prone skin?

Centella Asiatica and Niacinamide help soothe your skin and manage oil, while Sodium Hyaluronate and Glycerin keep your face feeling balanced and comfortable. This blend is unlikely to cause irritation and supports your skin barrier to help you manage breakouts.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/), [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/)

### What does Centella Asiatica do for oily acne-prone skin?

Centella asiatica helps calm redness, reduce acne breakouts, and improve moisture while supporting skin barrier repair. It may also help decrease inflammation and excess oil.
Sources: [Molecules, 2023](https://pubmed.ncbi.nlm.nih.gov/37446936/), [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/)

### What does Hyaluronic Acid do for oily acne-prone skin?

Hyaluronic acid helps calm oily acne-prone skin by reducing sebum production and lipid synthesis in sebaceous glands. It also supports skin barrier function and improves hydration while helping deliver treatments without causing irritation.
Sources: [The Journal of Investigative Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28163068/), [Journal of Cosmetic Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/35796638/)

### Where does this serum go in a skincare routine for oily acne-prone skin?

This treatment goes in the evening routine after cleansing and toning, and before moisturizing. Putting it in the evening helps keep things simple and adds extra safety around sun exposure.

### Can I use this serum with retinol, and in what order?

You can use this moisturizing treatment with retinol by applying it before your retinol to keep your skin calm and comfortable. This type of routine helps minimize dryness and irritation while supporting your skin barrier during active treatments.
Sources: [Cutis, 2006](https://pubmed.ncbi.nlm.nih.gov/17121065/), [Journal of Drugs in Dermatology, 2012](https://pubmed.ncbi.nlm.nih.gov/22648223/)

### How often should I use this serum?

This treatment is a great fit for your oily acne-prone skin and is designed to be used in your evening routine. Using it daily helps soothe redness and calm breakouts while keeping your skin balanced and hydrated.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/), [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/)

### Can this serum clog pores, cause breakouts or purging for oily acne-prone skin?

This moisturizing treatment is unlikely to clog pores or cause breakouts for oily acne-prone skin, as it contains soothing Centella Asiatica and Niacinamide to calm inflammation and help balance oil production without harsh ingredients.
Sources: [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/)

### Can I use this serum around the eyes or on my body?

You can use this moisturizing treatment around your eyes and on your body, as its gentle ingredients are safe for delicate areas and thinner skin. The soothing botanicals and hydrators like glycerin and hyaluronic acid help keep sensitive and dry spots calm and comfortable without irritation.
Sources: [Surgical and Radiologic Anatomy, 2002](https://pubmed.ncbi.nlm.nih.gov/12375070/), [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Is this serum fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for oily acne-prone skin

- [innisfree Green Tea Seed Hyaluronic Acid Hydrating Serum](https://lovi.care/skincare/sa/p/innisfree/green-tea-seed-hyaluronic-acid-hydrating-serum/for/oily-acne-prone-skin) — Superior fit — SAR 120.00 at Amazon
- [Elizavecca Witch Piggy Hell Pore Control Hyaluronic Acid 97%](https://lovi.care/skincare/sa/p/elizavecca/witch-piggy-hell-pore-control-hyaluronic-acid-97/for/oily-acne-prone-skin) — Superior fit — SAR 80.75 at Amazon
- [Torriden DIVE-IN Low Molecular Hyaluronic Acid Serum](https://lovi.care/skincare/sa/p/torriden/dive-in-low-molecular-hyaluronic-acid-serum/for/oily-acne-prone-skin) — Superior fit — SAR 69.70 at Amazon

## Pairs well with

- Cleanser: [CeraVe Foaming Facial Cleanser](https://lovi.care/skincare/sa/p/cerave/foaming-facial-cleanser/for/oily-acne-prone-skin) — Superior fit — SAR 36.33 at Amazon
- Hydrating Toner: [Paula's Choice Pore-Reducing Toner](https://lovi.care/skincare/sa/p/paula-s-choice/skin-balancing-pore-reducing-toner/for/oily-acne-prone-skin) — Superior fit — SAR 166.90 at Amazon
- SPF: [Dear, Klairs All-day Airy Sunscreen](https://lovi.care/skincare/sa/p/dear-klairs/all-day-airy-sunscreen/for/oily-acne-prone-skin) — Superior fit — SAR 148.78 at Amazon

## Where to buy

- Amazon.sa: SAR 44.92 (https://www.amazon.sa/dp/B0B5WRBK93?tag=lovisa02-21&linkCode=osi&th=1&psc=1)
Prices checked 3 Nov 2026.

## Ingredients

Centella Asiatica Extract, Butylene Glycol, Niacinamide, 1,2-Hexanediol, Water, Hydroxyacetophenone, Carbomer, Glycereth-25 Pca Isostearate, Ethylhexylglycerin, Tromethamine, Sodium Hyaluronate, Betula Platyphylla Japonica Juice, Melia Azadirachta Leaf Extract, Melia Azadirachta Flower Extract, Propanediol, Musa Sapientum Flower Extract, Coccinia Indica Fruit Extract, Rosa Damascena Flower Water, Pyrus Communis Fruit Extract, Prunus Domestica Fruit Extract, Aloe Barbadensis Flower Extract, Cucumis Melo Fruit Extract, Solanum Melongena Fruit Extract, Hedera Helix Stem Extract Leaf, Ocimum Sanctum Leaf Extract, Glycerin, Anastatica Hierochuntica Extract, Corallina Officinalis Extract, Curcuma Longa Root Extract, Hydrolyzed Hyaluronic Acid, Portulaca Oleracea Extract, Artemisia Princeps Extract, Rhodiola Rosea Root Extract
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/skin1004/madagascar-centella-hyalu-cica-first-ampoule/for/oily-acne-prone-skin
- United Kingdom: https://lovi.care/skincare/uk/p/skin1004/madagascar-centella-hyalu-cica-first-ampoule/for/oily-acne-prone-skin
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- Singapore: https://lovi.care/skincare/sg/p/skin1004/madagascar-centella-hyalu-cica-first-ampoule/for/oily-acne-prone-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/skin1004/madagascar-centella-hyalu-cica-first-ampoule/for/oily-acne-prone-skin (this page)
- United Arab Emirates: https://lovi.care/skincare/ae/p/skin1004/madagascar-centella-hyalu-cica-first-ampoule/for/oily-acne-prone-skin