# SKIN1004 Madagascar Centella Asiatica Ampoule for combination skin

**Lovi Fit: Average fit for combination skin.**
Combination Skin Fit: High · Effectiveness: Average · Safety: Excellent.

Page: https://lovi.care/skincare/sa/p/skin1004/madagascar-centella-asiatica-ampoule/for/combination-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Saudi Arabia.

Brand: [SKIN1004](https://lovi.care/skincare/sa/brands/skin1004)
Category: [Serums and treatments](https://lovi.care/skincare/sa/best/serums)

This fit is calculated for the concerns frequently associated with combination skin: an oily T-zone, enlarged pores, and dry cheeks. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for combination skin; other serums fit it better.

## Why this fit

- Suitable for combination skin, this product offers moderate soothing and barrier support due to Centella Asiatica Extract, which calms irritation and enhances resilience. Glycerin and Butylene Glycol provide hydration, which is supportive for oily shine and combination skin, but lacks specialized ingredients to directly address these concerns.
- The safety profile is excellent, with no risks of irritation for your combination skin due to the absence of prohibited or harsh ingredients and the presence of soothing ingredients like Centella Asiatica Extract.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/sa/p/skin1004/madagascar-centella-asiatica-ampoule/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/sa/p/skin1004/madagascar-centella-asiatica-ampoule/for/dry-skin): High
- [Combination skin](https://lovi.care/skincare/sa/p/skin1004/madagascar-centella-asiatica-ampoule/for/combination-skin): Average (this page)
- [Sensitive skin](https://lovi.care/skincare/sa/p/skin1004/madagascar-centella-asiatica-ampoule/for/sensitive-skin): High
- [Acne-prone skin](https://lovi.care/skincare/sa/p/skin1004/madagascar-centella-asiatica-ampoule/for/acne-prone-skin): High
- [Skin with dark spots](https://lovi.care/skincare/sa/p/skin1004/madagascar-centella-asiatica-ampoule/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/sa/p/skin1004/madagascar-centella-asiatica-ampoule/for/mature-skin): Average
- [Dry sensitive skin](https://lovi.care/skincare/sa/p/skin1004/madagascar-centella-asiatica-ampoule/for/dry-sensitive-skin): Average
- [Oily acne-prone skin](https://lovi.care/skincare/sa/p/skin1004/madagascar-centella-asiatica-ampoule/for/oily-acne-prone-skin): High

## Key ingredients

Centella Asiatica Extract, Glycerin, Butylene Glycol, 1,2-Hexanediol

## What the research says

- Cosmetic formulations containing 5% Centella asiatica extract showed the best efficacy in improving skin moisture and decreasing transepidermal water loss, while also exhibiting antiinflammatory properties in 25 volunteers compared to baseline measurements. ([Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/))
- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Co-delivery of paeonol and madecassoside via nanoemulsions improved transdermal delivery, promoted barrier repair proteins, inhibited inflammatory cytokine secretion in cellular and 3D models, and reduced transepidermal water loss and acne in human facial skin compared to free components. ([Molecules, 2023](https://pubmed.ncbi.nlm.nih.gov/37446936/))
- Topical application of 0.05% w/w ECa 233 gel reduced erythema index by 0.03 U and improved early crusting and general wound appearance compared to placebo in thirty individuals undergoing facial laser resurfacing. ([Journal of Alternative and Complementary Medicine, 2020](https://pubmed.ncbi.nlm.nih.gov/32310680/))
- Moisturizer containing 5% panthenol, madecassoside, and copper-zinc-manganese decreased adverse reactions and downtime after ablative fractional carbon dioxide laser resurfacing with comparable efficacy to 0.02% triamcinolone acetonide cream in 20 subjects. ([Journal of Cosmetic Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30945430/))
- Topical treatment with 5% vitamin C and 0.1% madecassoside significantly improved clinical scores for wrinkles, suppleness, firmness, roughness, and skin hydration, along with functional and structural remodeling of the elastic fiber network in 20 female volunteers with photoaged skin after 6 months compared to baseline. ([Experimental Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/18503551/))
- The emollient V0034CR significantly reduced TEWL compared to vehicle and vehicle plus glycerol, and significantly increased corneometry scores compared to vehicle and vehicle plus petrolatum in healthy volunteers with dry skin, demonstrating combined barrier function improvement from petrolatum and hydration improvement from glycerol. ([Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31532576/))
- Ten days of treatment with a cream containing 20% glycerin significantly increased skin hydration measured by corneometer values in 17 healthy volunteers compared to a placebo cream, but showed no influence on transepidermal water loss or skin sensitivity to an irritating surfactant. ([International Journal of Cosmetic Science, 2001](https://pubmed.ncbi.nlm.nih.gov/18498456/))
- Niacinamide/glycerin body moisturizers provided better rapid and prolonged improvement of cosmetic xerosis through functional improvement of stratum corneum barrier function compared to no treatment and conventional moisturizers in female subjects. ([Journal of Drugs in Dermatology, 2012](https://pubmed.ncbi.nlm.nih.gov/22206073/))
- A red ginseng hydrogel formulation with 1,2-hexanediol promoted selective growth of Staphylococcus epidermidis and decreased Cutibacterium acnes in 20 female subjects. ([Journal of Ginseng Research, 2022](https://pubmed.ncbi.nlm.nih.gov/35509819/))
- Sensory skin irritation potential of 1,2-alkanediols increased with alkane chain length, whereas 1,2-hexanediol showed the lowest objective skin irritation potential compared to both shorter and longer chain lengths, and percutaneous absorption negatively correlated with alkane chain length. ([International Journal of Cosmetic Science, 2011](https://pubmed.ncbi.nlm.nih.gov/21585401/))

## Why other serums fit combination skin better

- Niacinamide and ferulic acid incorporated in a stable multiple emulsion successfully reduced melanin, sebum, and skin erythema while improving skin elasticity and hydration in human skin compared to a placebo. ([BioMed Research International, 2022](https://pubmed.ncbi.nlm.nih.gov/35342760/))
- A panthenol-enriched mask improved skin hydration, regulated sebum, and reduced redness and TEWL across dry sensitive, oily sensitive, and oily acne skin subgroups with excellent tolerance and no adverse reactions. ([Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38366684/))

## What reviewers say

Based on a very large amount of data, users describe this ampoule as a gentle, watery product that effectively calms redness and repairs the moisture barrier without feeling heavy. It is highly praised by individuals with sensitive, acne-prone, or irritated skin. Some users with resilient skin types find it too lightweight for significant hydration or notice minimal changes.

- Liked: Lightweight texture (mostly mentioned)
- Liked: Soothes redness (mostly mentioned)
- Liked: Safe for sensitive skin (often mentioned)
- Liked: Hydrating for oily skin (sometimes noted)
- Disliked: No visible results (sometimes noted)
- Disliked: Caused breakouts (rarely noted)
- Disliked: Not hydrating enough (rarely noted)

## How to apply

- Use your serum as part of your PM routine. Start using it 3 times a week and move to daily use if your skin likes it.
- Apply the serum after cleansing and toner, and right before your moisturizer.
- Gently press 2-3 drops of the serum into your skin and wait a minute ⏳for it to soak in.
- Apply the serum on clean and dry skin since your skin is not sensitive.
- Always do a patch test before using the serum for the first time, and avoid the eye area .
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### How well does SKIN1004 Centella Ampoule work for combination skin?

This ampoule works moderately well for combination skin by calming irritation and providing basic hydration, though other products fit it better. Treatments that fit combination skin best need ingredients like niacinamide, zinc PCA, or propolis to regulate oiliness, enhance radiance, and balance dry and oily areas.
Sources: [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/), [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Which ingredients make this serum a good fit for combination skin?

Centella Asiatica Extract, Glycerin, and Butylene Glycol make this serum a good fit by helping to calm irritation, support the skin barrier, and provide gentle hydration for dry and oily areas. To work best for combination skin, a treatment of this type needs ingredients like niacinamide, propolis, or zinc PCA to regulate oiliness and enhance radiance without causing irritation.
Sources: [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/), [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### What does Centella Asiatica Extract do for combination skin?

Centella Asiatica Extract helps balance combination skin by boosting moisture levels while keeping redness and irritation calm. It also supports skin barrier repair to help maintain smooth and healthy skin overall.
Sources: [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/), [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### What does Glycerin do for combination skin?

Glycerin helps keep combination skin soft and smooth by pulling moisture in and keeping it there. It improves hydration and supports your skin barrier, which is unlikely to cause irritation.
Sources: [The British Journal of Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/18510666/), [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Where does this serum go in a skincare routine for combination skin?

This treatment goes in the evening routine after cleansing and before moisturizing, which keeps the routine simple and safe around sun exposure.

### Can I use this serum with retinol, and in what order?

You can use this treatment alongside retinol by applying the serum first to calm your skin and provide basic hydration before layering your retinol product. It is very safe and unlikely to cause irritation for your combination skin. A product for this skin type also needs targeted ingredients to actively balance oil and refine pores.
Sources: [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/), [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### How often should I use this serum?

This treatment is used in the evening for your combination skin, starting once a week or as your routine directs for extra safety and simplicity. Centella Asiatica Extract helps calm irritation and Glycerin provides hydration, though combination skin also needs specialized ingredients to fully balance oily shine.
Sources: [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/), [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Can this serum clog pores, cause breakouts or purging for combination skin?

This serum is unlikely to cause breakouts or clog pores for your combination skin. Its safe formula lacks harsh ingredients that typically trigger irritation, and reviewers report a negligible risk of breakouts.

### Is this serum fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for combination skin

- [Beauty of Joseon Propolis + Niacinamide Glow Serum](https://lovi.care/skincare/sa/p/beauty-of-joseon/propolis-niacinamide-glow-serum/for/combination-skin) — Superior fit — SAR 226.83 at Amazon
- [Augustinus Bader The Serum](https://lovi.care/skincare/sa/p/augustinus-bader/the-serum/for/combination-skin) — Superior fit — SAR 2,799.99 at Amazon
- [SkinCeuticals C E Ferulic](https://lovi.care/skincare/sa/p/skinceuticals/c-e-ferulic/for/combination-skin) — Superior fit — SAR 865.37 at Amazon

## Pairs well with

- Cleanser: [Fresh Soy Face Cleanser](https://lovi.care/skincare/sa/p/fresh/soy-face-cleanser/for/combination-skin) — Superior fit — SAR 191.00 at Amazon
- Hydrating Toner: [Paula's Choice Pore-Reducing Toner](https://lovi.care/skincare/sa/p/paula-s-choice/skin-balancing-pore-reducing-toner/for/combination-skin) — Superior fit — SAR 166.90 at Amazon
- Moisturizer: [COSRX Oil-Free Ultra-Moisturizing Lotion with Birch Sap](https://lovi.care/skincare/sa/p/cosrx/oil-free-ultra-moisturizing-lotion-with-birch-sap/for/combination-skin) — Superior fit — SAR 39.70 at Amazon

## Where to buy

- Amazon.sa: SAR 26.76 (https://www.amazon.sa/dp/B07ZKHPV9Y?tag=lovisa02-21&linkCode=osi&th=1&psc=1)
Prices checked 6 Nov 2026.

## Ingredients

Centella Asiatica Extract, Water, Glycerin, Butylene Glycol, 1,2-Hexanediol, Phenoxyethanol, Cellulose Gum
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/skin1004/madagascar-centella-asiatica-ampoule/for/combination-skin
- United Kingdom: https://lovi.care/skincare/uk/p/skin1004/madagascar-centella-asiatica-ampoule/for/combination-skin
- Ireland: https://lovi.care/skincare/ie/p/skin1004/madagascar-centella-asiatica-ampoule/for/combination-skin
- Germany: https://lovi.care/skincare/de/p/skin1004/madagascar-centella-asiatica-ampoule/for/combination-skin
- France: https://lovi.care/skincare/fr/p/skin1004/madagascar-centella-asiatica-ampoule/for/combination-skin
- Italy: https://lovi.care/skincare/it/p/skin1004/madagascar-centella-asiatica-ampoule/for/combination-skin
- Netherlands: https://lovi.care/skincare/nl/p/skin1004/madagascar-centella-asiatica-ampoule/for/combination-skin
- Spain: https://lovi.care/skincare/es/p/skin1004/madagascar-centella-asiatica-ampoule/for/combination-skin
- Canada: https://lovi.care/skincare/ca/p/skin1004/madagascar-centella-asiatica-ampoule/for/combination-skin
- Australia: https://lovi.care/skincare/au/p/skin1004/madagascar-centella-asiatica-ampoule/for/combination-skin
- Singapore: https://lovi.care/skincare/sg/p/skin1004/madagascar-centella-asiatica-ampoule/for/combination-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/skin1004/madagascar-centella-asiatica-ampoule/for/combination-skin (this page)
- United Arab Emirates: https://lovi.care/skincare/ae/p/skin1004/madagascar-centella-asiatica-ampoule/for/combination-skin