# Numbuzin No.2 Protein 43% Creamy Serum for dry skin

**Lovi Fit: High fit for dry skin.**
Dry Skin Fit: High · Effectiveness: Superior · Safety: Excellent.

Page: https://lovi.care/skincare/sa/p/numbuzin/no-2-protein-43-creamy-serum/for/dry-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Saudi Arabia.

Brand: [Numbuzin](https://lovi.care/skincare/sa/brands/numbuzin)
Category: [Moisturizers and moisturizing serums](https://lovi.care/skincare/sa/best/moisturizers)

This fit is calculated for the concerns frequently associated with dry skin: flakiness, tightness, dehydration, fine lines, and wrinkles. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

A great choice for dry skin; a few moisturizers fit it even better.

## Why this fit

- Highly suitable for your dry skin as oat extract protein and ceramide np provide emollient and barrier repair actions, addressing your dry or flaky skin concerns with targeted moisturization.
- Rice seed protein and hydrolyzed corn protein further enhance hydration and smoothing texture, supporting your skin's barrier function.
- The formulation is safe for your dry skin, containing soothing ingredients and lacking harsh components.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/sa/p/numbuzin/no-2-protein-43-creamy-serum/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/sa/p/numbuzin/no-2-protein-43-creamy-serum/for/dry-skin): High (this page)
- [Combination skin](https://lovi.care/skincare/sa/p/numbuzin/no-2-protein-43-creamy-serum/for/combination-skin): Average
- [Sensitive skin](https://lovi.care/skincare/sa/p/numbuzin/no-2-protein-43-creamy-serum/for/sensitive-skin): Average
- [Acne-prone skin](https://lovi.care/skincare/sa/p/numbuzin/no-2-protein-43-creamy-serum/for/acne-prone-skin): Average
- [Skin with dark spots](https://lovi.care/skincare/sa/p/numbuzin/no-2-protein-43-creamy-serum/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/sa/p/numbuzin/no-2-protein-43-creamy-serum/for/mature-skin): High
- [Dry sensitive skin](https://lovi.care/skincare/sa/p/numbuzin/no-2-protein-43-creamy-serum/for/dry-sensitive-skin): High
- [Oily acne-prone skin](https://lovi.care/skincare/sa/p/numbuzin/no-2-protein-43-creamy-serum/for/oily-acne-prone-skin): Average

## Key ingredients

Content Protein, Rice Seed Protein, Hydrolyzed Protein, Ceramide Np, Cholesterol

## What the research says

- A lipid mixture enriched by ceramide NP with fatty acids of diverse chain lengths significantly improved skin barrier recovery rate, stratum corneum integrity, and hydration compared to a vehicle cream in healthy adult male volunteers with corticosteroid-impaired skin. ([Skin Pharmacology and Physiology, 2022](https://pubmed.ncbi.nlm.nih.gov/34348350/))
- Emulsions containing ceramides 1 and 3 improved skin hydration and reduced transepidermal water loss in sodium lauryl sulfate-irritated skin of fifteen healthy Asian women compared to a control emulsion. ([International Journal of Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/18717861/))
- Topical application of oyster protein hydrolysates peptides protected against UVB-induced skin photodamage in mice by alleviating moisture loss, epidermal hyperplasia, and fiber degradation through antioxidant and anti-inflammatory mechanisms. ([Marine Drugs, 2020](https://pubmed.ncbi.nlm.nih.gov/32486363/))
- Rice protein hydrolysate and its characteristic peptides Leu-Leu-Lys, Leu-Pro-Lys, and pyroGlu-Lys reduced melanin content, tyrosinase activity, and ROS production in UVB-induced human epidermal melanocyte PIG1 cells by regulating the JNK/Β-Trcp/NFΗB-p65/MITF signaling pathway and lowering TRP-1 and TRP-2 expression. ([Food & Function, 2020](https://pubmed.ncbi.nlm.nih.gov/32955075/))
- A liquid formulation containing hydrolyzed collagen demonstrated structural stability, peptide mass distribution between 0.5 and 19.5 kDa, and faded forehead wrinkles in five volunteers while proving to be non-irritating and hypoallergenic. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/32390321/))
- Combined treatment with human umbilical cord mesenchymal stem cell-derived exosomes and hydrolyzed collagen oligopeptides enhanced proliferation and migration, reduced reactive oxygen species and senescence-associated beta-galactosidase activity, increased type I and type III collagen expression, and decreased metalloproteinases, inflammatory cytokines, and senescence markers in human skin fibroblasts compared to either treatment alone. ([Molecules, 2024](https://pubmed.ncbi.nlm.nih.gov/38611748/))
- Collagen peptides induced cell proliferation and pro-collagen-1α expression, increased TGF-β and VEGF, and suppressed the LPS-induced inflammatory response in human skin fibroblasts and keratinocytes. ([Nutrients, 2022](https://pubmed.ncbi.nlm.nih.gov/36501011/))
- Botulinum toxin-A encapsulated in phosphatidylcholine/cholesterol nanoliposomes delivered transdermally achieved a diffusion depth of 380 μm and showed a nonsignificant advantage in relieving post-acne scarring compared to hyaluronic acid hydrogel treatment in 12 facial patients. ([Journal of Materials Science. Materials in Medicine, 2024](https://pubmed.ncbi.nlm.nih.gov/39073502/))
- Topical application of cholesterol sulfate increases stratum corneum thickness and inhibits protease-induced cell dissociation by competitively inhibiting serine proteases in mice and human stratum corneum. ([The Journal of Investigative Dermatology, 1998](https://pubmed.ncbi.nlm.nih.gov/9699715/))
- Topical lovastatin treatment impairs the recovery of cutaneous permeability barrier function and stratum corneum cholesterol levels after acetone disruption in mice, an effect normalized by simultaneous treatment with mevalonate or cholesterol. ([The Journal of Clinical Investigation, 1990](https://pubmed.ncbi.nlm.nih.gov/2243142/))

## What reviewers say

This serum is widely praised as a "winter savior" for dry, sensitive, and dehydrated skin, effectively repairing damaged barriers and alleviating flakiness. Users consistently report a plump, healthy glow and deep "inner" hydration, though its rich, protein-heavy formula can be too heavy or potentially pore-clogging for oily or acne-prone skin types.

- Liked: Deep barrier repair (mostly mentioned)
- Liked: Long-lasting hydration (often mentioned)
- Liked: Rich creamy texture (often mentioned)
- Liked: Glowy finish (sometimes noted)
- Disliked: Not for oily skin (sometimes noted)
- Disliked: Potential breakouts (sometimes noted)
- Disliked: Stickiness/tackiness (sometimes noted)
- Disliked: Packaging issues (rarely noted)

## How to apply

- Could be used as part of your AM or PM routine. Start using it 3 times a week and work your way up to daily use.
- Apply your moisturizer after your toner and before your sunscreen in the morning. At night, use it as the final step after your serum.
- Gently press a small amount of the moisturizer into your skin. Avoid rubbing to keep your dry skin happy.
- Apply the moisturizer on slightly damp skin to help lock in extra hydration. This is great for soothing dry and flaky areas .
- Avoid the sensitive eye area and do a patch test before your first use .
- Video: https://storage.pora.ai/2f72f5d69f07beeafc30237f829efbff.mp4

## Questions and answers

### What makes Numbuzin No.2 Protein 43% Creamy Serum a great fit for dry skin?

This serum is a great fit because oat extract protein and ceramide NP deeply moisturize dry skin and repair your skin barrier. Rice seed protein and hydrolyzed corn protein also help smooth your skin and boost lasting hydration.
Sources: [Skin Pharmacology and Physiology, 2022](https://pubmed.ncbi.nlm.nih.gov/34348350/)

### Which ingredients make this serum a good fit for dry skin?

This serum is a great fit for dry skin because it contains oat extract protein and ceramide np, which help smooth away flakes and repair your skin barrier. Rice seed protein and hydrolyzed corn protein also work together to boost hydration and keep your skin soft.
Sources: [Skin Pharmacology and Physiology, 2022](https://pubmed.ncbi.nlm.nih.gov/34348350/)

### What does Content Protein do for dry skin?

Content Protein helps dry skin by boosting hydration, making the skin feel soft and smooth, and reinforcing the skin barrier to lock in moisture. Topical application of similar peptide formulas has been shown to increase moisture levels and improve overall water-holding capacity.
Sources: [Skin Research and Technology, 2008](https://pubmed.ncbi.nlm.nih.gov/18412569/), [International Journal of Cosmetic Science, 2001](https://pubmed.ncbi.nlm.nih.gov/18498478/)

### What does Rice Seed Protein do for dry skin?

Rice Seed Protein helps moisturize dry skin and calms irritation. It also supports the skin barrier and protects against damage from the sun.
Sources: [Journal of Cosmetic Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/35587098/)

### Where does this serum go in a skincare routine for dry skin?

This serum goes in the evening routine after cleansing and before moisturizing. Using it at night keeps things simple and avoids extra sun sensitivity.

### Can I use this serum with niacinamide, and in what order?

You can use this serum with niacinamide by applying niacinamide first and following with this moisturizing treatment. This combination helps smooth texture and restore moisture while keeping dry skin calm.
Sources: [Skin Pharmacology and Physiology, 2022](https://pubmed.ncbi.nlm.nih.gov/34348350/)

### How often should I use this serum?

You can use this treatment in the evening as part of your routine for dry skin. Daily application of moisturizers and barrier-repair ingredients like ceramide NP helps keep dry or flaky skin smooth and hydrated.
Sources: [Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/32141711/), [Health Science Reports, 2021](https://pubmed.ncbi.nlm.nih.gov/34141902/)

### Can this serum clog pores, cause breakouts or purging for dry skin?

This serum may cause breakouts for some, as reviewers note moderate complaints about potential blemishes. However, it is generally unlikely to irritate dry skin since its formulation includes soothing ingredients and lacks harsh components.

### Can I use this serum around the eyes or on my body?

You can use this serum around the eyes and on your body as its gentle, moisturizing ingredients are safe for these areas. It helps hydrate dry or flaky skin and supports the skin barrier using proteins and ceramide NP.
Sources: [Skin Pharmacology and Physiology, 2022](https://pubmed.ncbi.nlm.nih.gov/34348350/)

### Is this serum fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for dry skin

- [Revision Skincare Hydrating Serum](https://lovi.care/skincare/sa/p/revision-skincare/hydrating-serum/for/dry-skin) — High fit — SAR 515.82 at Amazon
- [Isntree Green Tea Fresh Serum](https://lovi.care/skincare/sa/p/isntree/green-tea-fresh-serum/for/dry-skin) — High fit — SAR 58.98 at Amazon
- [innisfree Green Tea Seed Hyaluronic Acid Hydrating Serum](https://lovi.care/skincare/sa/p/innisfree/green-tea-seed-hyaluronic-acid-hydrating-serum/for/dry-skin) — High fit — SAR 120.00 at Amazon

## Pairs well with

- Cleanser: [La Roche-Posay Hydrating Gentle Cleanser](https://lovi.care/skincare/sa/p/la-roche-posay/toleriane-hydrating-gentle-cleanser/for/dry-skin) — Superior fit — SAR 297.00 at Amazon
- SPF: [d'Alba Piedmont Waterfull Mild Sunscreen](https://lovi.care/skincare/sa/p/d-alba/piedmont-waterfull-mild-sunscreen/for/dry-skin) — Superior fit — SAR 75.00 at Amazon
- Pre-Cleanser: [MISSHA Ultra Hyalon Cleansing Cream](https://lovi.care/skincare/sa/p/missha/ultra-hyalon-cleansing-cream/for/dry-skin) — Superior fit — SAR 65.11 at Amazon

## Where to buy

No store in Saudi Arabia has a checked price for this product, so the page shows none.

## Ingredients

Voat Extract Protein, Water, Cyclopentasiloxane, Butylene Glycol, Cetearyl Ethyl Hexanoate, Cyclohexasiloxane, Phenyl Trimethicone, Cetyl Pg, Sebum-10 1 Dimethicone, Hydrogenate Tid Poly, Rice Seed Protein, Prunus Amygdalus Dulcis Protein, Hydrolyzed Corn Protein, Hydrolyzed Protein, Hydrolyzed Pea Protein, Hydrolyzed Milk Protein, Glycine Soja Protein Soybean Protein, Hydrolyzed Lupine Protein, Ceramide Np, Cholesterol
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/numbuzin/no-2-protein-43-creamy-serum/for/dry-skin
- United Kingdom: https://lovi.care/skincare/uk/p/numbuzin/no-2-protein-43-creamy-serum/for/dry-skin
- Ireland: https://lovi.care/skincare/ie/p/numbuzin/no-2-protein-43-creamy-serum/for/dry-skin
- Germany: https://lovi.care/skincare/de/p/numbuzin/no-2-protein-43-creamy-serum/for/dry-skin
- France: https://lovi.care/skincare/fr/p/numbuzin/no-2-protein-43-creamy-serum/for/dry-skin
- Italy: https://lovi.care/skincare/it/p/numbuzin/no-2-protein-43-creamy-serum/for/dry-skin
- Netherlands: https://lovi.care/skincare/nl/p/numbuzin/no-2-protein-43-creamy-serum/for/dry-skin
- Spain: https://lovi.care/skincare/es/p/numbuzin/no-2-protein-43-creamy-serum/for/dry-skin
- Canada: https://lovi.care/skincare/ca/p/numbuzin/no-2-protein-43-creamy-serum/for/dry-skin
- Australia: https://lovi.care/skincare/au/p/numbuzin/no-2-protein-43-creamy-serum/for/dry-skin
- Singapore: https://lovi.care/skincare/sg/p/numbuzin/no-2-protein-43-creamy-serum/for/dry-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/numbuzin/no-2-protein-43-creamy-serum/for/dry-skin (this page)
- United Arab Emirates: https://lovi.care/skincare/ae/p/numbuzin/no-2-protein-43-creamy-serum/for/dry-skin