# No7 Protect & Perfect Intense Advanced Serum for oily acne-prone skin

**Lovi Fit: Average fit for oily acne-prone skin.**
Oily Skin Fit: Average · Effectiveness: Average · Safety: High.

Page: https://lovi.care/skincare/sa/p/no7/protect-and-perfect-intense-advanced-serum/for/oily-acne-prone-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Saudi Arabia.

Brand: [No7](https://lovi.care/skincare/sa/brands/no7)
Category: [Serums and treatments](https://lovi.care/skincare/sa/best/serums)

This fit is calculated for the concerns frequently associated with oily acne-prone skin: shine, breakouts, blemishes, and enlarged pores. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for oily acne-prone skin; other serums fit it better.

## Why this fit

- Offers moderate suitability for oily skin as Sodium Ascorbyl Phosphate and Retinyl Palmitate provide antioxidant activity and collagen stimulation, but lacks sufficient ingredients for optimal oil control.
- The presence of Palmitoyl Oligopeptide and Palmitoyl Tetrapeptide-7 offers excellent anti-aging benefits by minimizing fine lines and wrinkles, though these do not directly address your primary concerns of acne and blemishes.
- The safety profile is good, with no risks of irritation for your oily skin due to the absence of prohibited or harsh ingredients.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/sa/p/no7/protect-and-perfect-intense-advanced-serum/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/sa/p/no7/protect-and-perfect-intense-advanced-serum/for/dry-skin): High
- [Combination skin](https://lovi.care/skincare/sa/p/no7/protect-and-perfect-intense-advanced-serum/for/combination-skin): Average
- [Sensitive skin](https://lovi.care/skincare/sa/p/no7/protect-and-perfect-intense-advanced-serum/for/sensitive-skin): Average
- [Acne-prone skin](https://lovi.care/skincare/sa/p/no7/protect-and-perfect-intense-advanced-serum/for/acne-prone-skin): Average
- [Skin with dark spots](https://lovi.care/skincare/sa/p/no7/protect-and-perfect-intense-advanced-serum/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/sa/p/no7/protect-and-perfect-intense-advanced-serum/for/mature-skin): Average
- [Dry sensitive skin](https://lovi.care/skincare/sa/p/no7/protect-and-perfect-intense-advanced-serum/for/dry-sensitive-skin): Average
- [Oily acne-prone skin](https://lovi.care/skincare/sa/p/no7/protect-and-perfect-intense-advanced-serum/for/oily-acne-prone-skin): Average (this page)

## Key ingredients

Sodium Ascorbyl Phosphate, Retinyl Palmitate, Acetyl Dipeptide-1 Cetyl Ester, Hydrolyzed Rice Protein, Dimethicone

## What the research says

- Retinyl palmitate-loaded non-ionic lamellar liquid crystalline systems provided a significant reduction of orbicular wrinkles in human volunteers compared to systems without retinyl palmitate. ([Colloids and Surfaces. B, Biointerfaces, 2011](https://pubmed.ncbi.nlm.nih.gov/21411295/))
- A multi-modal methodology combining MALDI-MSI, in vivo RCM, echography, and histology revealed age-related decreases in extracellular matrix and epidermal-dermal junction proteins and undulation depth, while a blend of palmitoyl oligopeptide and palmitoyl tetrapeptide-7 improved subepidermal low-echogenic band thickness, density, and extracellular matrix structure compared to placebo. ([Journal of Cosmetic Dermatology, 2015](https://pubmed.ncbi.nlm.nih.gov/25817264/))
- Palmitoyl tetrapeptide-7, acetyl hexapeptide-8, palmitoyl tripeptide-1, and palmitoyl tetrapeptide-10 significantly increased type III collagen levels in human dermal fibroblasts following UV exposure, with their combination demonstrating a greater effect in vitro and enhancing type I, III, and IV collagen levels in ex vivo skin tissues compared to individual components. ([International Journal of Cosmetic Science, 2026](https://pubmed.ncbi.nlm.nih.gov/42683869/))
- Retinyl palmitate ethosomal hydrogel reduced non-inflammatory and total acne lesion counts significantly better than marketed tretinoin while improving tolerability with minimal skin irritation in patients with acne vulgaris. ([International Journal of Nanomedicine, 2021](https://pubmed.ncbi.nlm.nih.gov/34211271/))
- Topical application of 5% vitamin C cream significantly improved global clinical scores, increased skin microrelief density, and induced elastic tissue repair in photoaged skin compared to excipient control in healthy female volunteers. ([Experimental Dermatology, 2003](https://pubmed.ncbi.nlm.nih.gov/12823436/))
- Ascorbic acid 2-glucoside gel significantly reduced gingival melanin pigmentation after 4 weeks compared to placebo in 73 subjects with symmetric pigmentation. ([Journal of Periodontology, 2009](https://pubmed.ncbi.nlm.nih.gov/19186973/))
- Topical application of VC-IP cream twice daily for 8 weeks reduces periorbital wrinkles in female subjects compared to a placebo cream. ([Journal of Cosmetic Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/34910367/))
- Over-the-counter retinol products provided only weak evidence for a mild ameliorating effect on fine facial skin wrinkle lines in randomized, double-blind, vehicle-controlled trials, and major methodological flaws call the validity of positive results into question. ([The Journal of Clinical and Aesthetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/34980969/))
- A cosmetic niacinamide/peptide/retinyl propionate regimen significantly improved periorbital wrinkle appearance relative to a 0.02% tretinoin regimen at 8 weeks with comparable benefits at 24 weeks, while demonstrating significantly better tolerability in 196 women. ([The British Journal of Dermatology, 2010](https://pubmed.ncbi.nlm.nih.gov/20374604/))
- A novel triple-active cosmetic formulation containing 4-hexylresorcinol, retinyl propionate, and niacinamide improved the visual appearance of photoageing similarly to 0.02% tretinoin and reversed a consensus gene signature associated with ageing in female adults while causing less skin irritation. ([International Journal of Cosmetic Science, 2024](https://pubmed.ncbi.nlm.nih.gov/38685700/))
- Cosmetic products containing 4-t-butylcyclohexanol demonstrated a faster and more pronounced soothing effect on capsaicin-induced burning compared to those containing acetyl dipeptide-1 cetyl ester in volunteers with sensitive skin. ([Journal of the European Academy of Dermatology and Venereology, 2016](https://pubmed.ncbi.nlm.nih.gov/26805418/))
- Rice protein hydrolysate and its characteristic peptides Leu-Leu-Lys, Leu-Pro-Lys, and pyroGlu-Lys reduced melanin content, tyrosinase activity, and ROS production in UVB-induced human epidermal melanocyte PIG1 cells by regulating the JNK/Β-Trcp/NFΗB-p65/MITF signaling pathway and lowering TRP-1 and TRP-2 expression. ([Food & Function, 2020](https://pubmed.ncbi.nlm.nih.gov/32955075/))
- Wearing an N95 mask alone compared to using dimethicone cream or hydrocolloid dressing caused more adverse skin reactions among 73 military health care workers, with no significant differences in fit test failure rates between groups. ([Military Medicine, 2024](https://pubmed.ncbi.nlm.nih.gov/38771104/))
- Treatment with a moisturizer containing dimethicone and glycerine increased epidermal thickness by 0.019 mm, improved barrier function by decreasing transepidermal water loss by 13%, decreased melanin intensity, and induced keratins 6 and 16 in fifteen women with moderately photoaged forearms. ([Clinical and Experimental Dermatology, 2007](https://pubmed.ncbi.nlm.nih.gov/17137484/))
- Externally applied substances such as ceramides, hyaluronic acid, licorice extracts, dimethicone, petrolatum, and paraffin wax treat skin disease resulting from damage to the skin barrier. ([Clinics in Dermatology, 2012](https://pubmed.ncbi.nlm.nih.gov/22507050/))

## Why other serums fit oily acne-prone skin better

- A cream combining propolis, tea tree oil, and Aloe vera reduced erythema scars, acne severity index, and total lesion count better than erythromycin cream in sixty patients with mild to moderate acne vulgaris compared to placebo. ([Clinical Pharmacology, 2018](https://pubmed.ncbi.nlm.nih.gov/30588129/))
- Niacinamide and ferulic acid incorporated in a stable multiple emulsion successfully reduced melanin, sebum, and skin erythema while improving skin elasticity and hydration in human skin compared to a placebo. ([BioMed Research International, 2022](https://pubmed.ncbi.nlm.nih.gov/35342760/))

## What reviewers say

Based on a very large amount of data, users with aging, dry, or combination skin frequently praise this serum for its silky texture and ability to instantly smooth and hydrate the skin. While many report visible improvements in fine lines and overall radiance after consistent use, results regarding deep wrinkles are mixed, with some users seeing significant firming and others noticing little change.

- Liked: Instant skin smoothing (mostly mentioned)
- Liked: Silky, lightweight texture (mostly mentioned)
- Liked: Quick absorption (often mentioned)
- Liked: Hydration and radiance (sometimes noted)
- Liked: Reduces fine lines (sometimes noted)
- Disliked: Lack of visible results (sometimes noted)
- Disliked: Silicone-heavy feel (sometimes noted)
- Disliked: Greasiness (rarely noted)
- Disliked: Packaging issues (rarely noted)
- Disliked: Skin irritation (rarely noted)

## How to apply

- Could be used as part of your PM routine. Start 3 times a week and build up to daily use if your skin tolerates it well.
- Apply your serum after cleansing and toning, but before putting on your moisturizer.
- Gently press 2 to 3 drops of the serum into your skin and let it absorb for a minute.
- Apply the serum on clean, dry skin to help manage your blemishes safely.
- Do a patch test before your first use and avoid the delicate eye area.
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### How well does No7 Protect & Perfect work for oily acne-prone skin?

No7 Protect & Perfect Intense Advanced Serum works moderately well for oily acne-prone skin, providing helpful antioxidants and anti-aging benefits while lacking sufficient ingredients for optimal oil control. This skin type needs products with ingredients like niacinamide, propolis, and vitamin C that control excess oil and target breakouts without heavy or pore-clogging components.
Sources: [International Journal of Nanomedicine, 2021](https://pubmed.ncbi.nlm.nih.gov/34211271/), [Colloids and Surfaces. B, Biointerfaces, 2011](https://pubmed.ncbi.nlm.nih.gov/21411295/)

### Which ingredients make this serum a good fit for oily acne-prone skin?

Sodium Ascorbyl Phosphate and retinyl palmitate help this serum fit your oily acne-prone skin by providing antioxidant activity and managing acne lesions. A product of this type for this skin needs ingredients like niacinamide and propolis for oil control and blemishes, along with soothing extracts and lightweight hydrators.
Sources: [International Journal of Nanomedicine, 2021](https://pubmed.ncbi.nlm.nih.gov/34211271/)

### What does Vitamin C do for oily acne-prone skin?

Vitamin C helps oily acne-prone skin by reducing breakouts, calming red spots, and controlling extra oil. Studies show that using it on the skin can help clear up acne pimples and keep oil production balanced.
Sources: [International Journal of Cosmetic Science, 2009](https://pubmed.ncbi.nlm.nih.gov/19134126/), [Drug Research, 2017](https://pubmed.ncbi.nlm.nih.gov/27756097/)

### What does Retinyl Palmitate do for oily acne-prone skin?

Retinyl palmitate helps manage acne-prone skin by reducing acne blemishes and spots while keeping skin irritation low. It works well for oily skin types because it supports normal skin cell turnover and helps keep pores clear, though this type of skin also needs ingredients that control excess oil and soothe inflammation.
Sources: [International Journal of Nanomedicine, 2021](https://pubmed.ncbi.nlm.nih.gov/34211271/), [Biochimica Et Biophysica Acta, 2012](https://pubmed.ncbi.nlm.nih.gov/21914489/)

### Where does this serum go in a skincare routine for oily acne-prone skin?

This serum goes in the evening routine after cleansing and before moisturizing. It has a safe design that is unlikely to irritate oily skin, but this type of product also needs strong oil-control ingredients to properly balance this skin type.

### Can I use this serum with retinol, and in what order?

You can use this serum with retinol, applying this treatment first in your evening routine and following with your retinol product. This serum is unlikely to cause irritation on oily skin, but to keep your skin clear and balanced, a product of this type for oily acne-prone skin needs strong oil control ingredients.

### How often should I use this serum?

This treatment works well in your evening routine, where you can apply it safely for simplicity and protection around sun exposure. This product of this type needs enough ingredients for oil control to truly suit oily acne-prone skin.

### Can this serum clog pores, cause breakouts or purging for oily acne-prone skin?

This serum is unlikely to cause breakouts or purging for your oily skin because it has a good safety profile with no harsh ingredients that typically trigger irritation. However, it lacks sufficient ingredients for optimal oil control, so oily acne-prone skin needs a product with targeted oil-balancing ingredients.

### Is this serum fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for oily acne-prone skin

- [Clinique Fresh Pressed Daily Booster with Pure Vitamin C 10%](https://lovi.care/skincare/sa/p/clinique/fresh-pressed-daily-booster-with-pure-vitamin-c-10/for/oily-acne-prone-skin) — Superior fit — SAR 653.00 at Amazon
- [Beauty of Joseon Propolis + Niacinamide Glow Serum](https://lovi.care/skincare/sa/p/beauty-of-joseon/propolis-niacinamide-glow-serum/for/oily-acne-prone-skin) — Superior fit — SAR 226.83 at Amazon
- [Neogen Dermalogy Real Vitamin C Serum](https://lovi.care/skincare/sa/p/neogen-dermalogy/real-vitamin-c-serum/for/oily-acne-prone-skin) — Superior fit — SAR 130.97 at Amazon

## Pairs well with

- Cleanser: [CeraVe Foaming Facial Cleanser](https://lovi.care/skincare/sa/p/cerave/foaming-facial-cleanser/for/oily-acne-prone-skin) — Superior fit — SAR 36.33 at Amazon
- Hydrating Toner: [Paula's Choice Pore-Reducing Toner](https://lovi.care/skincare/sa/p/paula-s-choice/skin-balancing-pore-reducing-toner/for/oily-acne-prone-skin) — Superior fit — SAR 166.90 at Amazon
- Moisturizer: [COSRX Oil-Free Ultra-Moisturizing Lotion with Birch Sap](https://lovi.care/skincare/sa/p/cosrx/oil-free-ultra-moisturizing-lotion-with-birch-sap/for/oily-acne-prone-skin) — Superior fit — SAR 39.70 at Amazon

## Where to buy

- Amazon.sa: SAR 124.26 (https://www.amazon.sa/dp/B0719SCY9M?tag=lovisa02-21&linkCode=osi&th=1&psc=1)
Prices checked 5 Nov 2026.

## Ingredients

Acetyl Dipeptide-1 Cetyl Ester, Water, Butylene Glycol, Carbomer, Cetyl Peg Ppg-10 1 Dimethicone, Dimethicone, Dimethicone Crosspolymer, Ethylhexylglycerin, Ethylparaben, Glycerin, Hexyl Laurate, Hydrolyzed Rice Protein, Hydroxyethylcellulose, Magnesium Sulfate, Medicago Sativa Extract, Methylparaben, Morus Alba Leaf Extract, Palmitoyl Oligopeptide, Palmitoyl Tetrapeptide-7, Panax Ginseng Root Extract, Peg Ppg-18 18 Dimethicone, Phenoxyethanol, Polyglyceryl-4 Isostearate, Polysorbate 20, Propylene Glycol, Retinyl Palmitate, Sodium Ascorbyl Phosphate, Sodium Benzoate, Sodium Hyaluronate, Sorbitan Laurate, Tocopherol, Tocopheryl Acetate
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/no7/protect-and-perfect-intense-advanced-serum/for/oily-acne-prone-skin
- United Kingdom: https://lovi.care/skincare/uk/p/no7/protect-and-perfect-intense-advanced-serum/for/oily-acne-prone-skin
- Ireland: https://lovi.care/skincare/ie/p/no7/protect-and-perfect-intense-advanced-serum/for/oily-acne-prone-skin
- Germany: https://lovi.care/skincare/de/p/no7/protect-and-perfect-intense-advanced-serum/for/oily-acne-prone-skin
- France: https://lovi.care/skincare/fr/p/no7/protect-and-perfect-intense-advanced-serum/for/oily-acne-prone-skin
- Italy: https://lovi.care/skincare/it/p/no7/protect-and-perfect-intense-advanced-serum/for/oily-acne-prone-skin
- Netherlands: https://lovi.care/skincare/nl/p/no7/protect-and-perfect-intense-advanced-serum/for/oily-acne-prone-skin
- Spain: https://lovi.care/skincare/es/p/no7/protect-and-perfect-intense-advanced-serum/for/oily-acne-prone-skin
- Canada: https://lovi.care/skincare/ca/p/no7/protect-and-perfect-intense-advanced-serum/for/oily-acne-prone-skin
- Australia: https://lovi.care/skincare/au/p/no7/protect-and-perfect-intense-advanced-serum/for/oily-acne-prone-skin
- Singapore: https://lovi.care/skincare/sg/p/no7/protect-and-perfect-intense-advanced-serum/for/oily-acne-prone-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/no7/protect-and-perfect-intense-advanced-serum/for/oily-acne-prone-skin (this page)
- United Arab Emirates: https://lovi.care/skincare/ae/p/no7/protect-and-perfect-intense-advanced-serum/for/oily-acne-prone-skin