# NIVEA DERMA SKIN CLEAR for mature skin

**Lovi Fit: Average fit for mature skin.**
Normal Skin Fit: High · Effectiveness: Average · Safety: Excellent.

Page: https://lovi.care/skincare/sa/p/nivea/derma-skin-clear/for/mature-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Saudi Arabia.

Brand: [NIVEA](https://lovi.care/skincare/sa/brands/nivea)
Category: [Serums and treatments](https://lovi.care/skincare/sa/best/serums)

This fit is calculated for the concerns frequently associated with mature skin: fine lines, wrinkles, and loss of firmness. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for mature skin; other serums fit it better.

## Why this fit

- Offers moderate treatment for acne-prone skin due to salicylic acid and niacinamide, which help reduce acne lesions and blemishes, but these ingredients are not targeted for your goal of reducing wrinkles and fine lines.
- Provides general skincare benefits like hydration and mild exfoliation from glycerin and salicylic acid, which are suitable for your normal skin type.
- The product is safe for your normal skin, as it lacks harsh ingredients and contains soothing panthenol.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/sa/p/nivea/derma-skin-clear/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/sa/p/nivea/derma-skin-clear/for/dry-skin): Caution
- [Combination skin](https://lovi.care/skincare/sa/p/nivea/derma-skin-clear/for/combination-skin): Average
- [Sensitive skin](https://lovi.care/skincare/sa/p/nivea/derma-skin-clear/for/sensitive-skin): Average
- [Acne-prone skin](https://lovi.care/skincare/sa/p/nivea/derma-skin-clear/for/acne-prone-skin): High
- [Skin with dark spots](https://lovi.care/skincare/sa/p/nivea/derma-skin-clear/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/sa/p/nivea/derma-skin-clear/for/mature-skin): Average (this page)
- [Dry sensitive skin](https://lovi.care/skincare/sa/p/nivea/derma-skin-clear/for/dry-sensitive-skin): Caution
- [Oily acne-prone skin](https://lovi.care/skincare/sa/p/nivea/derma-skin-clear/for/oily-acne-prone-skin): High

## Key ingredients

Salicylic Acid, Niacinamide, Glycerin, Panthenol, Citric Acid

## What the research says

- Twice daily application of a multitargeted dermocosmetic cream provided comparable efficacy to benzoyl peroxide 5% gel in reducing inflammatory, non-inflammatory, and total lesions in 150 Caucasian subjects with mild-to-moderate acne over 56 days, while demonstrating superior skin tolerability. ([Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/37941097/))
- The use of a salicylic acid-based dermocosmetic significantly reduces the needed quantity of benzoyl peroxide without impacting efficacy in mild to moderate acne, and as maintenance post-benzoyl peroxide allows a significant reduction of acne relapse compared to vehicle. ([Journal of Drugs in Dermatology, 2023](https://pubmed.ncbi.nlm.nih.gov/38051857/))
- A moisturizer containing licochalcone A, 1,2-decanediol, L-carnitine, and salicylic acid significantly reduced noninflammatory, inflammatory, and total acne lesion counts compared to a vehicle control in Thai patients during a 12-week maintenance phase. ([BioMed Research International, 2020](https://pubmed.ncbi.nlm.nih.gov/33150170/))
- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Topical dexpanthenol acts as a moisturizer, improves stratum corneum hydration, accelerates wound healing and epidermal regeneration, reduces erythema, and improves symptoms of skin irritation compared to vehicle or no pretreatment. ([American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/))
- Cryotherapy with liquid nitrogen achieved a higher cure rate (39%) than salicylic acid (24%) and a wait-and-see approach (16%) for cutaneous warts at 13 weeks in primary care patients. ([CMAJ, 2010](https://pubmed.ncbi.nlm.nih.gov/20837684/))
- Treatment with 2% supramolecular salicylic acid hydrogel resulted in a regression and markedly improvement rate of 51.01% compared to 43.10% for Adapaline gel in patients with mild to moderate facial acne vulgaris, showing no significant difference in efficacy. ([Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38590107/))
- Topical 5% benzoyl peroxide plus salicylic acid achieved the greatest lesion reduction at early 2 to 4 week time points compared to benzoyl peroxide, clindamycin, and combination benzoyl peroxide/clindamycin, while 5% benzoyl peroxide plus salicylic acid and combination benzoyl peroxide/clindamycin showed similar efficacy at 10 to 12 weeks in acne patients. ([Journal of the American Academy of Dermatology, 2010](https://pubmed.ncbi.nlm.nih.gov/20488582/))
- Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33103316/))
- Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women. ([The Journal of Investigative Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/17882270/))
- Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging. ([Dermatologic Surgery, 2005](https://pubmed.ncbi.nlm.nih.gov/16029679/))
- The emollient V0034CR significantly reduced TEWL compared to vehicle and vehicle plus glycerol, and significantly increased corneometry scores compared to vehicle and vehicle plus petrolatum in healthy volunteers with dry skin, demonstrating combined barrier function improvement from petrolatum and hydration improvement from glycerol. ([Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31532576/))
- Ten days of treatment with a cream containing 20% glycerin significantly increased skin hydration measured by corneometer values in 17 healthy volunteers compared to a placebo cream, but showed no influence on transepidermal water loss or skin sensitivity to an irritating surfactant. ([International Journal of Cosmetic Science, 2001](https://pubmed.ncbi.nlm.nih.gov/18498456/))
- Niacinamide/glycerin body moisturizers provided better rapid and prolonged improvement of cosmetic xerosis through functional improvement of stratum corneum barrier function compared to no treatment and conventional moisturizers in female subjects. ([Journal of Drugs in Dermatology, 2012](https://pubmed.ncbi.nlm.nih.gov/22206073/))
- Moisturizer containing 5% panthenol, madecassoside, and copper-zinc-manganese decreased adverse reactions and downtime after ablative fractional carbon dioxide laser resurfacing with comparable efficacy to 0.02% triamcinolone acetonide cream in 20 subjects. ([Journal of Cosmetic Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30945430/))
- Topical dexpanthenol formulated in lipophilic vehicles improved stratum corneum hydration and reduced transepidermal water loss compared to vehicle control in humans. ([Arzneimittel-Forschung, 2000](https://pubmed.ncbi.nlm.nih.gov/10965426/))
- Hyaluronic acid, hyaluronic acid plus dexpanthenol, and isotonic saline nasal sprays all significantly improved dry nose symptoms over four weeks in 240 patients, with hyaluronic acid plus dexpanthenol providing superior nasal moisturisation compared to the other two. ([Auris, Nasus, Larynx, 2020](https://pubmed.ncbi.nlm.nih.gov/32067777/))
- A novel composition containing salicylic acid, capryloyl salicylic acid, HEPES, glycolic acid, citric acid, and dioic acid showed similar tolerance and efficacy compared with clindamycin 1% and benzoyl peroxide 5% gel in subjects with acne vulgaris. ([Journal of Drugs in Dermatology, 2013](https://pubmed.ncbi.nlm.nih.gov/23545907/))
- Daily treatment with a facial serum containing multiple acids reduced post-inflammatory hyperchromia lesion grade and number by 29.4% at 56 days, and decreased skin oiliness by 30.7% at 7 days in Brazilian patients with acne vulgaris. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33617668/))
- Topical 20% citric acid lotion increases viable epidermal thickness and dermal glycosaminoglycan content in sun-damaged skin compared to vehicle alone. ([Dermatologic Surgery, 1997](https://pubmed.ncbi.nlm.nih.gov/9256916/))

## Why other serums fit mature skin better

- Topical application of retinol and retinoic acid both increased epidermal thickness and upregulated collagen genes and proteins in human skin, with retinol producing similar histological and molecular changes to retinoic acid alongside a significant reduction in facial wrinkles after 12 weeks. ([Journal of Cosmetic Dermatology, 2016](https://pubmed.ncbi.nlm.nih.gov/26578346/))
- A topical serum containing vitamin C, vitamin E, and raspberry leaf cell culture extract improved skin color, elasticity, radiance, smoothness, scaliness, and wrinkles compared to the untreated contralateral side in fifty female volunteers. ([Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31975502/))

## What reviewers say

Based on a very large amount of data, this range for oily and blemish-prone skin is highly effective at reducing active acne and improving skin texture, with many users noting clearer pores and balanced oil production without dryness. Some users with very oily skin experienced increased shine, and a small number reported initial breakouts or had mixed feelings about the scent and consistency.

- Liked: Clears active blemishes (mostly mentioned)
- Liked: Smoother skin texture (often mentioned)
- Liked: Good value for money (sometimes noted)
- Liked: Non-drying formula (sometimes noted)
- Disliked: Increases skin shine (rarely noted)
- Disliked: Initial skin purging (rarely noted)
- Disliked: Scent preferences (rarely noted)
- Disliked: Sticky consistency (rarely noted)

## How to apply

- Use this serum in your PM routine. Start by applying it 3 times a week, and work up to daily use if your skin likes it.
- Apply this serum after your toner and before your moisturizer.
- Gently press 2-3 drops of the serum into your skin and let it absorb for a minute.
- You can apply the serum on dry skin for the best results against fine lines.
- Always do a patch test before your first use and avoid the sensitive eye area.
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### How well does NIVEA Derma Skin Clear work for mature skin?

This product works moderately well to clear blemishes on normal skin, but it is not targeted for reducing wrinkles and fine lines. A treatment for mature skin needs to be exceptionally safe with no risk of irritation, effectively target wrinkles and fine lines with high-quality ingredients, and perform its intended anti-aging function excellently.
Sources: [American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/), [Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/37941097/)

### Which ingredients make this treatment a good fit for mature skin?

Glycerin, salicylic acid, and panthenol make this treatment a fit for mature skin by providing hydration and mild exfoliation while keeping the skin calm. However, because it lacks targeted ingredients for reducing wrinkles and fine lines, a treatment for mature skin needs potent antioxidants, hydrating components, skin-repairing ingredients, nourishing oils, and peptides.
Sources: [American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/)

### What does Salicylic Acid do for mature skin?

Salicylic acid helps smooth and firm mature skin by boosting collagen and elasticity while reducing roughness and wrinkles. It is unlikely to cause irritation when used correctly, but this skin type also needs extra hydrating ingredients to stay soft and plump.
Sources: [Aesthetic Plastic Surgery, 2025](https://pubmed.ncbi.nlm.nih.gov/38926250/)

### What does Niacinamide do for mature skin?

Niacinamide helps mature skin by smoothing out fine lines and wrinkles, reducing dark spots, and improving overall skin elasticity. It is also very well tolerated and supports a strong skin barrier to keep skin looking healthy.
Sources: [Antioxidants, 2021](https://pubmed.ncbi.nlm.nih.gov/34439563/), [Journal of Cosmetic Dermatology, 2004](https://pubmed.ncbi.nlm.nih.gov/17147561/)

### Where does this treatment go in a skincare routine for mature skin?

This treatment goes in the evening routine, as treatments with active ingredients are placed at night for simplicity and extra safety around sun exposure. Since this is an average fit for mature skin, a product of this type needs targeted anti-aging ingredients like peptides or retinol to help reduce wrinkles and fine lines.

### Can I use this treatment with retinol, and in what order?

It is unlikely to be safe or comfortable to use this treatment in the same routine as retinol, because combining salicylic acid and retinol may easily dry out and irritate your skin. To use both safely, apply this treatment in your evening routine on some nights and your retinol on alternating nights, or use this product in the morning and retinol at night.

### How often should I use this treatment?

Start by using this treatment once a week in the evening, and if your skin feels comfortable and you see good results, you may carefully use it more often. A product for mature skin also needs ingredients that help smooth fine lines and wrinkles, such as retinoids and antioxidants.
Sources: [Facial Plastic Surgery, 2014](https://pubmed.ncbi.nlm.nih.gov/24488631/)

### Can this treatment clog pores, cause breakouts or purging for mature skin?

This treatment is unlikely to clog pores, but initial breakouts or purging may happen with a low likelihood when you start using it. It is safe for your skin and helps keep it calm with soothing ingredients.
Sources: [Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/37941097/), [Journal of Drugs in Dermatology, 2023](https://pubmed.ncbi.nlm.nih.gov/38051857/)

### Is this treatment fragrance-free and alcohol-free?

It has no drying alcohol and contains fragrance (parfum).

## Alternatives for mature skin

- [Paula's Choice RESIST Super Antioxidant Concentrate Serum](https://lovi.care/skincare/sa/p/paula-s-choice/resist-super-antioxidant-concentrate-serum/for/mature-skin) — Superior fit — SAR 461.00 at Amazon
- [SkinCeuticals C E Ferulic](https://lovi.care/skincare/sa/p/skinceuticals/c-e-ferulic/for/mature-skin) — Superior fit — SAR 865.37 at Amazon
- [Drunk Elephant A-Passioni Retinol Cream](https://lovi.care/skincare/sa/p/drunk-elephant/a-passioni-retinol-cream/for/mature-skin) — High fit — SAR 491.04 at Amazon

## Pairs well with

- Cleanser: [Fresh Soy Face Cleanser](https://lovi.care/skincare/sa/p/fresh/soy-face-cleanser/for/mature-skin) — Superior fit — SAR 191.00 at Amazon
- Hydrating Toner: [COSRX Propolis Synergy Toner](https://lovi.care/skincare/sa/p/cosrx/full-fit-propolis-synergy-toner/for/mature-skin) — Superior fit — SAR 30.00 at Amazon
- Moisturizer: [Obagi Hydrate Luxe Moisture-Rich Cream](https://lovi.care/skincare/sa/p/obagi/hydrate-luxe/for/mature-skin) — Superior fit — SAR 329.18 at Amazon

## Where to buy

- Amazon.sa: SAR 90.30 (https://www.amazon.sa/dp/B0DG61WSVX?tag=lovisa02-21&linkCode=osi&th=1&psc=1)
Prices checked 5 Nov 2026.

## Ingredients

Water, Glycerin, Salicylic Acid, Niacinamide, Butylene Glycol, Sodium Hydroxide, Panthenol, Citric Acid, Sodium Citrate, Phenoxyethanol, Ethylhexylglycerin, Parfum
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/nivea/derma-skin-clear/for/mature-skin
- United Kingdom: https://lovi.care/skincare/uk/p/nivea/derma-skin-clear/for/mature-skin
- Ireland: https://lovi.care/skincare/ie/p/nivea/derma-skin-clear/for/mature-skin
- Germany: https://lovi.care/skincare/de/p/nivea/derma-skin-clear/for/mature-skin
- France: https://lovi.care/skincare/fr/p/nivea/derma-skin-clear/for/mature-skin
- Italy: https://lovi.care/skincare/it/p/nivea/derma-skin-clear/for/mature-skin
- Netherlands: https://lovi.care/skincare/nl/p/nivea/derma-skin-clear/for/mature-skin
- Spain: https://lovi.care/skincare/es/p/nivea/derma-skin-clear/for/mature-skin
- Canada: https://lovi.care/skincare/ca/p/nivea/derma-skin-clear/for/mature-skin
- Australia: https://lovi.care/skincare/au/p/nivea/derma-skin-clear/for/mature-skin
- Singapore: https://lovi.care/skincare/sg/p/nivea/derma-skin-clear/for/mature-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/nivea/derma-skin-clear/for/mature-skin (this page)
- United Arab Emirates: https://lovi.care/skincare/ae/p/nivea/derma-skin-clear/for/mature-skin