# NIOD Modulating Glucosides for sensitive skin

**Lovi Fit: High fit for sensitive skin.**
Normal Skin Fit: High · Effectiveness: High · Safety: High.

Page: https://lovi.care/skincare/sa/p/niod/modulating-glucosides/for/sensitive-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Saudi Arabia.

Brand: [NIOD](https://lovi.care/skincare/sa/brands/niod)
Category: [Serums and treatments](https://lovi.care/skincare/sa/best/serums)

This fit is calculated for the concerns frequently associated with sensitive skin: redness, stinging, and reactions to new products. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

A great choice for sensitive skin; a few serums fit it even better.

## Why this fit

- Highly suitable for your normal skin, this formula leverages Bisabolol and Epigallocatechin Gallatyl Glucoside to effectively calm redness and irritation. These ingredients work synergistically to reduce inflammation and provide antioxidant protection, aligning perfectly with your primary concerns.
- The inclusion of Tasmannia Lanceolata Leaf Extract and Mirabilis Jalapa Callus Extract further enhances the soothing properties, offering additional benefits for your sensitive skin.
- The product demonstrates an excellent safety profile, free from harsh or prohibited ingredients and enriched with soothing components, ensuring no risk of irritation for your sensitive skin.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/sa/p/niod/modulating-glucosides/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/sa/p/niod/modulating-glucosides/for/dry-skin): High
- [Combination skin](https://lovi.care/skincare/sa/p/niod/modulating-glucosides/for/combination-skin): High
- [Sensitive skin](https://lovi.care/skincare/sa/p/niod/modulating-glucosides/for/sensitive-skin): High (this page)
- [Acne-prone skin](https://lovi.care/skincare/sa/p/niod/modulating-glucosides/for/acne-prone-skin): Average
- [Skin with dark spots](https://lovi.care/skincare/sa/p/niod/modulating-glucosides/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/sa/p/niod/modulating-glucosides/for/mature-skin): High
- [Dry sensitive skin](https://lovi.care/skincare/sa/p/niod/modulating-glucosides/for/dry-sensitive-skin): High
- [Oily acne-prone skin](https://lovi.care/skincare/sa/p/niod/modulating-glucosides/for/oily-acne-prone-skin): High

## Key ingredients

Glucosides, Squalane, Superoxide Dismutase, Epigallocatechin Gallatyl Glucoside, Palmitoyl Tripeptide-8

## What the research says

- Squalane at 0.005-0.015% counteracts UVA-induced oxidative stress, inflammation, and collagen metabolism inhibition while stimulating fibroblast migration in human dermal fibroblasts. ([Molecules, 2025](https://pubmed.ncbi.nlm.nih.gov/40363772/))
- Plant-derived squalane protected human dermal fibroblasts against UVA-induced damage by counteracting ROS formation, suppressing apoptosis-related proteins p53, caspase-3, caspase-9, and PARP, and restoring the pro-survival p-Akt/mTOR pathway. ([Antioxidants, 2025](https://pubmed.ncbi.nlm.nih.gov/40722956/))
- Topical application of TAT-SOD significantly suppresses UVB-induced erythema formation, blood flow rise, and apoptotic sunburn cell formation in human volunteers compared to a vehicle control. ([European Journal of Pharmaceutics and Biopharmaceutics, 2016](https://pubmed.ncbi.nlm.nih.gov/27460952/))
- Topical treatment with the synthetic SOD/catalase mimetic EUK-134 reduced lipid peroxide levels both at baseline on non-irradiated human skin and at the surface of UVA-exposed skin when applied before or after irradiation, compared to controls. ([International Journal of Cosmetic Science, 2004](https://pubmed.ncbi.nlm.nih.gov/18492138/))
- Topical superoxide dismutase formulations maintained physical stability and enzymatic activity for 6 months at 4 and 30 degrees C, and effectively inhibited UVB-induced skin erythema for 48 hours, whereas formulations combined with alpha-tocopherol were unstable. ([European Journal of Pharmaceutics and Biopharmaceutics, 2007](https://pubmed.ncbi.nlm.nih.gov/17196809/))
- Topical green tea extract significantly improved clinical symptoms, tear breakup times, and meibomian gland health compared to standard treatment in patients with dry eye and Meibomian Gland Dysfunction. ([Journal of Clinical and Diagnostic Research, 2017](https://pubmed.ncbi.nlm.nih.gov/28384900/))
- Topical low-dose green tea extract reduces UVB-induced p53 expression and apoptosis in human skin keratinocytes compared to placebo. ([Experimental Dermatology, 2009](https://pubmed.ncbi.nlm.nih.gov/18631247/))
- An anti-acne hydrogel containing Aloe barbadensis, Garcinia mangostana, and Camellia sinensis extracts showed superior antiacne and antiblotch activities compared to 1% clindamycin gel in sixty subjects with mild-moderate acne. ([Clinical, Cosmetic and Investigational Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/31239743/))

## What reviewers say

This serum is highly praised for its ability to calm sensitive, reactive, and irritated skin, with users frequently reporting significant improvements in redness, stinging, and compromised skin barriers. It is a popular choice for those recovering from aesthetic treatments or harsh active ingredients. Some users with normal skin may find the benefits less noticeable or the texture slightly heavy.

- Liked: Calms sensitive skin (mostly mentioned)
- Liked: Reduces skin redness (often mentioned)
- Liked: Buffers active irritation (sometimes noted)
- Liked: Strengthens skin barrier (sometimes noted)
- Disliked: Inconvenient packaging (sometimes noted)
- Disliked: Subtle for normal skin (sometimes noted)
- Disliked: Can cause breakouts (rarely noted)
- Disliked: Unappealing scent (rarely noted)

## How to apply

- Use your serum in the PM routine, starting 3 times a week before building up to daily use if your skin is happy.
- Apply the serum after cleansing and toning, but before putting on your moisturizer for the best results.
- Gently press 2-3 drops of the serum into your skin and wait a minute ⏱ for it to soak in.
- Since your skin is sensitive and easily irritated, apply the serum on completely dry skin to help keep it calm.
- Always do a patch test before your first use and avoid getting the serum too close to your eyes .
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### What makes Modulating Glucosides a great fit for sensitive skin?

This treatment is a great fit because it uses ingredients like bisabolol and soothing plant extracts to calm redness and irritation on sensitive skin. It also has a safe formula that is free from harsh ingredients, ensuring it is very unlikely to cause any further irritation.

### Which ingredients make this serum a good fit for sensitive skin?

This serum is a great fit for sensitive skin because it uses bisabolol and epigallocatechin gallatyl glucoside to calm redness and irritation. Tasmannia lanceolata leaf extract and mirabilis jalapa callus extract further enhance these soothing properties to keep your skin comfortable and protected.

### What do Glucosides do for sensitive skin?

Glucosides help cleanse or carry ingredients for sensitive skin while showing an acceptable safety profile with little to no irritation. Clinical studies on human volunteers show that formulas using alkyl polyglucoside emulsifiers provide good skin hydration and are well tolerated by normal and irritated skin.
Sources: [Vojnosanitetski Pregled, 2016](https://pubmed.ncbi.nlm.nih.gov/29328637/), [Pharmaceutical Development and Technology, 2021](https://pubmed.ncbi.nlm.nih.gov/33428486/)

### What does Squalane do for sensitive skin?

Squalane helps calm sensitive skin by defending against everyday irritation and keeping it smooth and soft. It is unlikely to cause irritation and supports your skin barrier so it stays comfortable and hydrated.
Sources: [International Journal of Molecular Sciences, 2017](https://pubmed.ncbi.nlm.nih.gov/29280987/)

### Where does this serum go in a skincare routine for sensitive skin?

This treatment goes in the evening routine after your cleansing and toning steps, which helps keep things simple and safe for sensitive skin. This gentle formula is unlikely to cause irritation and works to calm redness.

### Can I use this serum with retinol, and in what order?

You can use this treatment alongside retinol by applying it first to calm the skin before layering your retinol, as it is very gentle and well-tolerated. This helps keep your skin comfortable and minimizes any redness or irritation that strong ingredients might cause.
Sources: [Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38102855/)

### How often should I use this serum?

This serum is a great fit for your sensitive skin and is used in the evening as part of your routine. It is unlikely to cause irritation and helps calm redness because it is free from harsh ingredients and enriched with soothing components.

### Can this serum clog pores, cause breakouts or purging for sensitive skin?

This serum is unlikely to cause breakouts or clog pores on sensitive skin because it has a very safe formula free from harsh ingredients and is enriched with calming components. Reviewers only rarely mention breakouts from using it.

### Is this serum fragrance-free and alcohol-free?

It has no drying alcohol and contains fragrance (benzyl alcohol).

## Alternatives for sensitive skin

- [Paula's Choice RESIST Super Antioxidant Concentrate Serum](https://lovi.care/skincare/sa/p/paula-s-choice/resist-super-antioxidant-concentrate-serum/for/sensitive-skin) — Superior fit — SAR 461.00 at Amazon
- [SkinCeuticals C E Ferulic](https://lovi.care/skincare/sa/p/skinceuticals/c-e-ferulic/for/sensitive-skin) — High fit — SAR 865.37 at Amazon
- [Neogen Dermalogy Real Vitamin C Serum](https://lovi.care/skincare/sa/p/neogen-dermalogy/real-vitamin-c-serum/for/sensitive-skin) — High fit — SAR 130.97 at Amazon

## Pairs well with

- Cleanser: [Fresh Soy Face Cleanser](https://lovi.care/skincare/sa/p/fresh/soy-face-cleanser/for/sensitive-skin) — Superior fit — SAR 191.00 at Amazon
- Soothing Toner: [Clarins Toning Lotion with Camomile](https://lovi.care/skincare/sa/p/clarins/soothing-toning-lotion/for/sensitive-skin) — Superior fit — SAR 141.00 at Amazon
- Moisturizer with Sun Protection: [Bioderma Bioderma Photoderm Mineral SPF 50+](https://lovi.care/skincare/sa/p/bioderma/photoderm-mineral-fluide-spf50/for/sensitive-skin) — Superior fit — SAR 132.22 at Amazon

## Where to buy

No store in Saudi Arabia has a checked price for this product, so the page shows none.

## Ingredients

Water, Squalane, Isodecyl Neopentanoate, Glycerin, Caprylic Capric Triglyceride, Pentylene Glycol, Propanediol, Hexyldecanol, Bisabolol, Butylene Glycol, Epigallocatechin Gallatyl Glucoside, Rosmarinyl Glucoside, Caffeyl Glucoside, Gallyl Glucoside, Tetrasodium Tetracarboxymethyl Naringeninchalcone, Hydroxymethoxyphenyl Decanone, 4-T-Butylcyclohexanol, Cetylhydroxyproline Palmitamide, Hydroxyphenyl Propamidobenzoic Acid, Palmitoyl Tripeptide-8, Superoxide Dismutase, Sodium Pca, Pca, Arginine, Glycine, Alanine, Serine, Valine, Isoleucine, Proline, Threonine, Histidine, Phenylalanine, Aspartic Acid, Sodium Lactate, Mirabilis Jalapa Callus Extract, Tasmannia Lanceolata Leaf Extract Fruit, Zingiber Officinale Root Extract, Curculigo Orchioides Root Extract, Isochrysis Galbana Extract, Brassica Campestris Sterols, Stearic Acid, Dextran, Isoceteth-20, Polyacrylate Crosspolymer-6, Xanthan Gum, Tocopherol, Propyl Gallate, Tromethamine, Dehydroacetic Acid, 1,2-Hexanediol, Benzyl Alcohol, Phenoxyethanol, Caprylyl Glycol
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/niod/modulating-glucosides/for/sensitive-skin
- United Kingdom: https://lovi.care/skincare/uk/p/niod/modulating-glucosides/for/sensitive-skin
- Ireland: https://lovi.care/skincare/ie/p/niod/modulating-glucosides/for/sensitive-skin
- Germany: https://lovi.care/skincare/de/p/niod/modulating-glucosides/for/sensitive-skin
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- Australia: https://lovi.care/skincare/au/p/niod/modulating-glucosides/for/sensitive-skin
- Singapore: https://lovi.care/skincare/sg/p/niod/modulating-glucosides/for/sensitive-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/niod/modulating-glucosides/for/sensitive-skin (this page)
- United Arab Emirates: https://lovi.care/skincare/ae/p/niod/modulating-glucosides/for/sensitive-skin