# Mylan Tretinoin for combination skin

**Lovi Fit: Low fit for combination skin.**
Combination Skin Fit: High · Effectiveness: Average · Safety: High.

Page: https://lovi.care/skincare/sa/p/mylan/tretinoin/for/combination-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Saudi Arabia.

Brand: [Mylan](https://lovi.care/skincare/sa/brands/mylan)
Category: [Serums and treatments](https://lovi.care/skincare/sa/best/serums)

This fit is calculated for the concerns frequently associated with combination skin: an oily T-zone, enlarged pores, and dry cheeks. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

A weak match for combination skin; the serums alongside fit it better.

## Why this fit

- Offers moderate exfoliation for your combination skin, as tretinoin promotes skin cell turnover to address oily shine. Alcohol in the formula may cause dryness for some users.
- The presence of butylated hydroxytoluene offers antioxidant benefits, which is suitable for your skin type.
- The safety profile is excellent, with no risks of irritation due to the absence of prohibited or harsh ingredients.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/sa/p/mylan/tretinoin/for/oily-skin): Low
- [Dry skin](https://lovi.care/skincare/sa/p/mylan/tretinoin/for/dry-skin): Caution
- [Combination skin](https://lovi.care/skincare/sa/p/mylan/tretinoin/for/combination-skin): Low (this page)
- [Sensitive skin](https://lovi.care/skincare/sa/p/mylan/tretinoin/for/sensitive-skin): Caution
- [Acne-prone skin](https://lovi.care/skincare/sa/p/mylan/tretinoin/for/acne-prone-skin): Average
- [Skin with dark spots](https://lovi.care/skincare/sa/p/mylan/tretinoin/for/dark-spots): Caution
- [Mature skin](https://lovi.care/skincare/sa/p/mylan/tretinoin/for/mature-skin): Caution
- [Dry sensitive skin](https://lovi.care/skincare/sa/p/mylan/tretinoin/for/dry-sensitive-skin): Caution
- [Oily acne-prone skin](https://lovi.care/skincare/sa/p/mylan/tretinoin/for/oily-acne-prone-skin): Average

## Key ingredients

Tretinoin, Alcohol, Butylated Hydroxytoluene

## What the research says

- A galenic compound containing essential oils and tretinoin demonstrated anti-acne efficacy and anti-inflammatory activity, significantly reducing papular erythema and retinoid-induced rashes compared to clindamycin-tretinoin gel in sixty volunteers over 30 days. ([Clinical, Cosmetic and Investigational Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/32210603/))
- Tretinoin-loaded nano lipid carriers resulted in a significantly higher rate of decrease in acne lesions and greater reduction in porphyrin production compared to conventional tretinoin cream in patients with mild to moderate acne vulgaris. ([Archives of Dermatological Research, 2022](https://pubmed.ncbi.nlm.nih.gov/34146120/))
- Topical tretinoin improves clinical appearance of photoaging in terms of wrinkling, mottled hyperpigmentation, sallowness, and lentigines and is safe and well tolerated. ([International Journal of Women's Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/35620028/))
- Topical tretinoin daily application for 10 to 12 months produced an 80 percent increase in collagen I formation in photodamaged human skin compared with a 14 percent decrease with vehicle alone. ([The New England Journal of Medicine, 1993](https://pubmed.ncbi.nlm.nih.gov/8336752/))
- Topical tretinoin precursors and tretinoin showed no significant difference in efficacy for moderate to severe facial photodamage in 20 patients, while tretinoin precursors caused erythema six times less frequently. ([JAMA Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/35675051/))
- Topical cyproterone acetate alcohol lotion at 0.5% and 1% reduced total acne lesions and acne severity index significantly more than placebo in female patients with mild to moderate acne vulgaris. ([Dermatology Online Journal, 2006](https://pubmed.ncbi.nlm.nih.gov/16638440/))
- Topical patchouli alcohol significantly accelerated the recovery of UV-induced skin lesions in mice through antioxidant and anti-inflammatory actions and down-regulation of MMP-1 and MMP-3 expression compared to vehicle. ([European Journal of Pharmaceutical Sciences, 2014](https://pubmed.ncbi.nlm.nih.gov/25033712/))

## What reviewers say

Users report significant improvements in skin texture and clarity for acne and photoaging after an adjustment period. The cream formulation is generally well-tolerated and smooth, while the gel formulation is frequently described as having a poor, glue-like consistency that pills and has a strong alcohol smell.

- Disliked: Gel pills (mostly mentioned)
- Liked: Clears acne (often mentioned)
- Disliked: Severe dryness/peeling (often mentioned)
- Disliked: Strong alcohol smell (often mentioned)
- Liked: Anti-aging results (sometimes noted)
- Liked: Smooth cream (sometimes noted)
- Disliked: Initial purging (sometimes noted)

## How to apply

- Use your serum as part of your PM routine. Start using it 3 times a week and move to daily use if your skin likes it.
- Apply the serum after cleansing and toner, and right before your moisturizer.
- Gently press 2-3 drops of the serum into your skin and wait a minute ⏳for it to soak in.
- Apply the serum on clean and dry skin since your skin is not sensitive.
- Always do a patch test before using the serum for the first time, and avoid the eye area .
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### Why is Mylan Tretinoin Cream a weak match for combination skin?

Mylan Tretinoin is a weak match for combination skin because the alcohol in the formula may cause dryness for some users. To fit this skin well, a treatment of this type needs effective ingredients like niacinamide and propolis or zinc PCA that provide balance and hydration without causing excess oiliness or dryness.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/32210603/), [Archives of Dermatological Research, 2022](https://pubmed.ncbi.nlm.nih.gov/34146120/)

### Which ingredients make this cream a poor fit for combination skin?

Alcohol in this formula may cause dryness, making it a weak match for combination skin. Treatments that fit combination skin well need helpful ingredients like niacinamide, propolis, or zinc PCA to balance oil and hydration without causing dryness.

### What does Tretinoin do for combination skin?

Tretinoin helps clear breakouts and smooth out uneven texture by speeding up skin renewal. Because it can be drying, combination skin needs a gentle moisturizer and daily sunscreen to protect the skin barrier while using this ingredient.
Sources: [Archives of Dermatological Research, 2022](https://pubmed.ncbi.nlm.nih.gov/34146120/), [International Journal of Women's Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/35620028/)

### What does Alcohol do for combination skin?

Alcohol in skincare helps products dry down fast and feel lightweight on combination skin, but it may dry out the cheeks and upset the skin barrier with frequent use. A formula for combination skin needs gentle hydration and soothing ingredients to balance these drying effects.
Sources: [Pharmaceutics, 2025](https://pubmed.ncbi.nlm.nih.gov/40006563/), [International Journal of Toxicology, 2008](https://pubmed.ncbi.nlm.nih.gov/18569160/)

### Where does this cream go in a skincare routine for combination skin?

This treatment goes in the evening routine after cleansing and before your moisturizer. Combination skin needs a product that balances oily areas without causing dryness, using hydrating and soothing ingredients.

### Can I use it with benzoyl peroxide, and in what order?

You can use this treatment with benzoyl peroxide, but it may cause dryness and irritation on combination skin, so alternating days or using them at different times of day helps prevent discomfort. This type of skin needs gentle soothing ingredients and hydrating moisturizers to keep it calm and balanced while using strong treatments.
Sources: [American Family Physician, 2012](https://pubmed.ncbi.nlm.nih.gov/23062156/), [Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38102855/)

### How often should I use it?

Start by using this treatment once a week in your evening routine, and if your skin feels fine, you may carefully use it more often. Because this product contains alcohol which may cause dryness, combination skin needs a formula with soothing hydrators and gentle moisturizers to keep it balanced.

### Can this cream clog pores, cause breakouts or purging for combination skin?

Yes, initial purging may happen when using this treatment on combination skin. Alcohol in the formula may also cause dryness for some users, and a product for this skin needs soothing, hydrating ingredients to balance the cell turnover.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/32210603/), [Archives of Dermatological Research, 2022](https://pubmed.ncbi.nlm.nih.gov/34146120/)

## Alternatives for combination skin

- [Beauty of Joseon Propolis + Niacinamide Glow Serum](https://lovi.care/skincare/sa/p/beauty-of-joseon/propolis-niacinamide-glow-serum/for/combination-skin) — Superior fit — SAR 226.83 at Amazon
- [Augustinus Bader The Serum](https://lovi.care/skincare/sa/p/augustinus-bader/the-serum/for/combination-skin) — Superior fit — SAR 2,799.99 at Amazon
- [SkinCeuticals C E Ferulic](https://lovi.care/skincare/sa/p/skinceuticals/c-e-ferulic/for/combination-skin) — Superior fit — SAR 865.37 at Amazon

## Routine for combination skin

### AM

- Cleanser: [Fresh Soy Face Cleanser](https://lovi.care/skincare/sa/p/fresh/soy-face-cleanser/for/combination-skin) — Superior fit — SAR 191.00 at Amazon
- Hydrating Toner: [Paula's Choice Pore-Reducing Toner](https://lovi.care/skincare/sa/p/paula-s-choice/skin-balancing-pore-reducing-toner/for/combination-skin) — Superior fit — SAR 166.90 at Amazon
- Moisturizer: [COSRX Oil-Free Ultra-Moisturizing Lotion with Birch Sap](https://lovi.care/skincare/sa/p/cosrx/oil-free-ultra-moisturizing-lotion-with-birch-sap/for/combination-skin) — Superior fit — SAR 39.70 at Amazon
- SPF: [CeraVe AM Facial Moisturizing Lotion](https://lovi.care/skincare/sa/p/cerave/am-facial-moisturizing-lotion-spf-30/for/combination-skin) — Superior fit — SAR 46.95 at Amazon

### PM

- Pre-Cleanser: [Shu Uemura Ultime8 Sublime Beauty Cleansing Oil](https://lovi.care/skincare/sa/p/shu-uemura/ultime8-sublime-beauty-cleansing-oil/for/combination-skin) — Superior fit — SAR 245.95 at Amazon
- Cleanser: [Fresh Soy Face Cleanser](https://lovi.care/skincare/sa/p/fresh/soy-face-cleanser/for/combination-skin) — Superior fit — SAR 191.00 at Amazon
- Cleansing Toner: [Medicube Zero Pore Pad 2.0](https://lovi.care/skincare/sa/p/medicube/zero-pore-pad-2-0/for/combination-skin) — Superior fit — SAR 64.80 at Amazon
- Serum or Treatment: [Peach & Lily Glass Skin Refining Serum](https://lovi.care/skincare/sa/p/peach-and-lily/glass-skin-refining-serum/for/combination-skin) — Superior fit — SAR 222.00 at Amazon
- Moisturizer: [COSRX Oil-Free Ultra-Moisturizing Lotion with Birch Sap](https://lovi.care/skincare/sa/p/cosrx/oil-free-ultra-moisturizing-lotion-with-birch-sap/for/combination-skin) — Superior fit — SAR 39.70 at Amazon

### Weekly

- Pre-Cleanser: [Shu Uemura Ultime8 Sublime Beauty Cleansing Oil](https://lovi.care/skincare/sa/p/shu-uemura/ultime8-sublime-beauty-cleansing-oil/for/combination-skin) — Superior fit — SAR 245.95 at Amazon
- Cleanser: [Fresh Soy Face Cleanser](https://lovi.care/skincare/sa/p/fresh/soy-face-cleanser/for/combination-skin) — Superior fit — SAR 191.00 at Amazon
- Enzyme Powder: [Dermalogica Daily Microfoliant](https://lovi.care/skincare/sa/p/dermalogica/daily-microfoliant/for/combination-skin) — Superior fit — SAR 157.51 at Amazon
- Cleansing Mask: [Kora Organics Turmeric Brightening & Exfoliating Mask](https://lovi.care/skincare/sa/p/kora-organics/turmeric-brightening-and-exfoliating-mask/for/combination-skin) — Superior fit — SAR 168.77 at Amazon
- Hydrating Toner: [Paula's Choice Pore-Reducing Toner](https://lovi.care/skincare/sa/p/paula-s-choice/skin-balancing-pore-reducing-toner/for/combination-skin) — Superior fit — SAR 166.90 at Amazon
- Serum or Treatment: [Peach & Lily Glass Skin Refining Serum](https://lovi.care/skincare/sa/p/peach-and-lily/glass-skin-refining-serum/for/combination-skin) — Superior fit — SAR 222.00 at Amazon

## Where to buy

No store in Saudi Arabia has a checked price for this product, so the page shows none.

## Ingredients

Tretinoin, Alcohol, Butylated Hydroxytoluene, Hydroxypropyl Cellulose
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/mylan/tretinoin/for/combination-skin
- United Kingdom: https://lovi.care/skincare/uk/p/mylan/tretinoin/for/combination-skin
- Ireland: https://lovi.care/skincare/ie/p/mylan/tretinoin/for/combination-skin
- Germany: https://lovi.care/skincare/de/p/mylan/tretinoin/for/combination-skin
- France: https://lovi.care/skincare/fr/p/mylan/tretinoin/for/combination-skin
- Italy: https://lovi.care/skincare/it/p/mylan/tretinoin/for/combination-skin
- Netherlands: https://lovi.care/skincare/nl/p/mylan/tretinoin/for/combination-skin
- Spain: https://lovi.care/skincare/es/p/mylan/tretinoin/for/combination-skin
- Canada: https://lovi.care/skincare/ca/p/mylan/tretinoin/for/combination-skin
- Australia: https://lovi.care/skincare/au/p/mylan/tretinoin/for/combination-skin
- Singapore: https://lovi.care/skincare/sg/p/mylan/tretinoin/for/combination-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/mylan/tretinoin/for/combination-skin (this page)
- United Arab Emirates: https://lovi.care/skincare/ae/p/mylan/tretinoin/for/combination-skin