# Mesoestetic Cosmelan 2 for oily skin

**Lovi Fit: Average fit for oily skin.**
Oily Skin Fit: High · Effectiveness: Average · Safety: High.

Page: https://lovi.care/skincare/sa/p/mesoestetic/cosmelan-2/for/oily-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Saudi Arabia.

Brand: [Mesoestetic](https://lovi.care/skincare/sa/brands/mesoestetic)
Category: [Serums and treatments](https://lovi.care/skincare/sa/best/serums)

This fit is calculated for the concerns frequently associated with oily skin: shine, enlarged pores, blackheads, and blemishes. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for oily skin; other serums fit it better.

## Why this fit

- Offers moderate exfoliation and tone evening for your oily skin due to the presence of salicylic acid and azelaic acid, which help regulate oil production and address hyperpigmentation.
- While ingredients like Glycerin and Aloe Barbadensis Leaf Juice provide beneficial hydration and soothing effects, they are less relevant to your primary concern of oily shine.
- The product is safe for your oily skin, with no risks of irritation from harsh ingredients and the inclusion of soothing agents like Bisabolol and Glycyrrhiza Glabra Root Extract.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/sa/p/mesoestetic/cosmelan-2/for/oily-skin): Average (this page)
- [Dry skin](https://lovi.care/skincare/sa/p/mesoestetic/cosmelan-2/for/dry-skin): Low
- [Combination skin](https://lovi.care/skincare/sa/p/mesoestetic/cosmelan-2/for/combination-skin): Average
- [Sensitive skin](https://lovi.care/skincare/sa/p/mesoestetic/cosmelan-2/for/sensitive-skin): Low
- [Acne-prone skin](https://lovi.care/skincare/sa/p/mesoestetic/cosmelan-2/for/acne-prone-skin): Average
- [Skin with dark spots](https://lovi.care/skincare/sa/p/mesoestetic/cosmelan-2/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/sa/p/mesoestetic/cosmelan-2/for/mature-skin): Average
- [Dry sensitive skin](https://lovi.care/skincare/sa/p/mesoestetic/cosmelan-2/for/dry-sensitive-skin): Low
- [Oily acne-prone skin](https://lovi.care/skincare/sa/p/mesoestetic/cosmelan-2/for/oily-acne-prone-skin): Average

## Key ingredients

Kojic Acid, Ascorbic Acid, Retinyl Palmitate, Niacinamide, Alpha-Arbutin

## What the research says

- Application of 15% azelaic acid gel significantly reduced post-inflammatory erythema and hyperpigmentation, decreased hemoglobin and melanin content, improved quality of life, and contributed to acne improvement in patients with mild to moderate acne compared to placebo. ([Dermatology and Therapy, 2024](https://pubmed.ncbi.nlm.nih.gov/38734843/))
- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Licochalcone A activated Nrf2 signaling, elevated cytoprotective enzymes, increased the reduced-to-oxidized glutathione ratio, and decreased reactive oxygen species in human fibroblasts and neutrophils, while a LicA-rich licorice extract lowered UVA-induced oxidative processes in vivo. ([Experimental Dermatology, 2015](https://pubmed.ncbi.nlm.nih.gov/25381913/))
- A topical formulation containing kojic acid, emblica extract, and glycolic acid demonstrated efficacy parity compared with hydroquinone 4% in multiethnic participants with mild to moderate facial dyschromia. ([Cutis, 2010](https://pubmed.ncbi.nlm.nih.gov/21049734/))
- A nanoemulsion containing 1 mg/mL kojic dipalmitate and 5% rosehip oil demonstrated high incorporation efficiency, suitable physicochemical stability, antioxidant and depigmenting efficacy close to 1 mM ascorbic acid, and no cytotoxicity at concentrations from 0.06% to 1% in vitro. ([Pharmaceutics, 2023](https://pubmed.ncbi.nlm.nih.gov/36839792/))
- Topical application of iron chelators kojic acid and deferiprone significantly accelerated wound healing in rats compared to control groups, with deferiprone showing superior efficacy due to higher antioxidant and iron chelation abilities. ([International Wound Journal, 2013](https://pubmed.ncbi.nlm.nih.gov/22621771/))
- Topical application of 5% vitamin C cream significantly improved global clinical scores, increased skin microrelief density, and induced elastic tissue repair in photoaged skin compared to excipient control in healthy female volunteers. ([Experimental Dermatology, 2003](https://pubmed.ncbi.nlm.nih.gov/12823436/))
- Ascorbic acid 2-glucoside gel significantly reduced gingival melanin pigmentation after 4 weeks compared to placebo in 73 subjects with symmetric pigmentation. ([Journal of Periodontology, 2009](https://pubmed.ncbi.nlm.nih.gov/19186973/))
- Topical application of VC-IP cream twice daily for 8 weeks reduces periorbital wrinkles in female subjects compared to a placebo cream. ([Journal of Cosmetic Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/34910367/))
- Over-the-counter retinol products provided only weak evidence for a mild ameliorating effect on fine facial skin wrinkle lines in randomized, double-blind, vehicle-controlled trials, and major methodological flaws call the validity of positive results into question. ([The Journal of Clinical and Aesthetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/34980969/))
- A cosmetic niacinamide/peptide/retinyl propionate regimen significantly improved periorbital wrinkle appearance relative to a 0.02% tretinoin regimen at 8 weeks with comparable benefits at 24 weeks, while demonstrating significantly better tolerability in 196 women. ([The British Journal of Dermatology, 2010](https://pubmed.ncbi.nlm.nih.gov/20374604/))
- A novel triple-active cosmetic formulation containing 4-hexylresorcinol, retinyl propionate, and niacinamide improved the visual appearance of photoageing similarly to 0.02% tretinoin and reversed a consensus gene signature associated with ageing in female adults while causing less skin irritation. ([International Journal of Cosmetic Science, 2024](https://pubmed.ncbi.nlm.nih.gov/38685700/))
- Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33103316/))
- Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women. ([The Journal of Investigative Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/17882270/))
- Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging. ([Dermatologic Surgery, 2005](https://pubmed.ncbi.nlm.nih.gov/16029679/))
- A non-hydroquinone topical formulation (SKNB19) improved hyperpigmentation by 28.5% in patient self-assessment and 27% in independent reviewer assessment compared with 4% hydroquinone in 18 adult subjects, while showing significantly less irritation and better tolerability. ([Journal of Cosmetic Science, 2020](https://pubmed.ncbi.nlm.nih.gov/33022197/))
- Encapsulation of alpha arbutin in an optimized ethosomal gel significantly improved skin melanin reduction, moisture content, and elasticity in human volunteers compared to conventional formulations. ([Heliyon, 2023](https://pubmed.ncbi.nlm.nih.gov/37681127/))
- Combining a home-based radiofrequency device and arbutin cream reduced mMASI scores by 25.6% and melanin index by 22.8% at 8 weeks compared to baseline in 38 participants. ([Journal of Cosmetic Dermatology, 2025](https://pubmed.ncbi.nlm.nih.gov/39918262/))

## What reviewers say

Based on limited data, users with stubborn hormonal melasma, sun spots, and post-inflammatory hyperpigmentation report significant improvements in skin clarity and texture, often describing the product as a "holy grail" for evening skin tone. The treatment is intense, with many users noting that success requires tolerating an adjustment period of redness, peeling, and sensitivity that mimics a mild sunburn.

- Liked: Fades stubborn melasma (mostly mentioned)
- Disliked: Severe redness peeling (mostly mentioned)
- Liked: Evens skin tone (often mentioned)
- Disliked: High price point (often mentioned)
- Liked: Improves skin texture (sometimes noted)
- Liked: Prevents reoccurrence (sometimes noted)
- Disliked: Painful application (sometimes noted)
- Disliked: Requires social downtime (sometimes noted)

## How to apply

- Use this serum in your PM routine. Start by applying it 3 times a week and build up to daily use if your skin tolerates it well.
- Apply the serum after cleansing and toning, but right before your moisturizer for the best results.
- Gently press 2-3 drops of the serum into your skin. Let it absorb ⏱ for a minute before applying the next product.
- Apply the serum on clean and dry skin since your skin is not sensitive and you want to target oily shine. This helps control excess oil throughout the night.
- Avoid the delicate eye area and do a patch test before using the serum for the very first time.
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### How well does Cosmelan 2 work for oily skin?

Mesoestetic Cosmelan 2 works moderately well for oily skin by offering gentle exfoliation and evening out your tone, though other treatments fit this skin type better. To achieve an ideal fit for oily skin, a treatment needs ingredients like niacinamide to control excess oil and shine while keeping pores clear.
Sources: [Dermatology and Therapy, 2024](https://pubmed.ncbi.nlm.nih.gov/38734843/)

### Which ingredients make this cream a good fit for oily skin?

Salicylic acid and azelaic acid make this cream a fit by helping regulate oil production and evening out skin tone for oily skin. To work even better for this skin type, a treatment needs effective ingredients like niacinamide that control sebum production and enhance radiance without irritation, alongside a balance of soothing extracts and hydrators.
Sources: [Dermatology and Therapy, 2024](https://pubmed.ncbi.nlm.nih.gov/38734843/)

### What does Kojic Acid do for oily skin?

Kojic acid helps fade dark spots and even out skin tone by slowing down the pigment production in oily skin. It is generally well tolerated, though products of this type for oily skin also need balancing ingredients to control shine and keep pores clear.
Sources: [Biomedicine & Pharmacotherapy = Biomedecine & Pharmacotherapie, 2019](https://pubmed.ncbi.nlm.nih.gov/30537675/), [The Journal of Pharmacy and Pharmacology, 1994](https://pubmed.ncbi.nlm.nih.gov/7714722/)

### What does Vitamin C do for oily skin?

Vitamin C helps brighten skin tone and smooth texture while providing antioxidant protection that prevents sebum oxidation. For oily skin, this type of product typically needs to be paired with oil-controlling or pore-clearing ingredients like salicylic acid or plant extracts.
Sources: [International Journal of Cosmetic Science, 2005](https://pubmed.ncbi.nlm.nih.gov/18492184/), [Journal of Cosmetic Dermatology, 2023](https://pubmed.ncbi.nlm.nih.gov/37128827/)

### Where does this cream go in a skincare routine for oily skin?

This treatment goes in the evening routine after cleansing and toning. Oily skin works best with a treatment that includes lightweight hydrators, oil-controlling acids, and soothing ingredients.

### Can I use this cream with retinol, and in what order?

You can use this treatment alongside retinol, but apply this cream first in your routine to let its active ingredients work directly on your skin. Because this product already contains exfoliating ingredients and retinoids, using them together may increase the likelihood of dryness or sensitivity. Oily skin works best with products that provide targeted oil control and blemish-clearing ingredients like salicylic acid and niacinamide without adding unnecessary heaviness.

### How often should I use this cream?

Start by using this cream once a week in the evening, and if your skin tolerates it well and shows good results, you may carefully use it more often. This product of this type needs ingredients like salicylic acid and azelaic acid to regulate oil production and address dark spots on oily skin.
Sources: [Dermatology and Therapy, 2024](https://pubmed.ncbi.nlm.nih.gov/38734843/)

### Can this cream clog pores, cause breakouts or purging for oily skin?

This cream is unlikely to clog pores or cause breakouts on oily skin, as it contains salicylic acid and azelaic acid to help clear skin and manage oil. However, an oily skin type needs a lighter formula focused mainly on balancing oil and controlling shine rather than heavy hydrators.
Sources: [Dermatology and Therapy, 2024](https://pubmed.ncbi.nlm.nih.gov/38734843/)

### Is this cream fragrance-free and alcohol-free?

It has no fragrance and contains drying alcohol (alcohol).

## Alternatives for oily skin

- [Clinique Fresh Pressed Daily Booster with Pure Vitamin C 10%](https://lovi.care/skincare/sa/p/clinique/fresh-pressed-daily-booster-with-pure-vitamin-c-10/for/oily-skin) — Superior fit — SAR 653.00 at Amazon
- [Beauty of Joseon Propolis + Niacinamide Glow Serum](https://lovi.care/skincare/sa/p/beauty-of-joseon/propolis-niacinamide-glow-serum/for/oily-skin) — Superior fit — SAR 226.83 at Amazon
- [SkinCeuticals C E Ferulic](https://lovi.care/skincare/sa/p/skinceuticals/c-e-ferulic/for/oily-skin) — High fit — SAR 865.37 at Amazon

## Pairs well with

- Cleanser: [CeraVe Foaming Facial Cleanser](https://lovi.care/skincare/sa/p/cerave/foaming-facial-cleanser/for/oily-skin) — Superior fit — SAR 36.33 at Amazon
- Hydrating Toner: [SOME BY MI Snail Truecica Miracle Repair Toner](https://lovi.care/skincare/sa/p/some-by-mi/snail-truecica-miracle-repair-toner/for/oily-skin) — Superior fit — SAR 53.04 at Amazon
- Moisturizer: [COSRX Oil-Free Ultra-Moisturizing Lotion with Birch Sap](https://lovi.care/skincare/sa/p/cosrx/oil-free-ultra-moisturizing-lotion-with-birch-sap/for/oily-skin) — Superior fit — SAR 39.70 at Amazon

## Where to buy

No store in Saudi Arabia has a checked price for this product, so the page shows none.

## Ingredients

Water, Acacia Senegal Gum, Alcohol, Allantoin, Aloe Barbadensis Leaf Juice, Alpha-Arbutin, Aminoethylphosphinic Acid, Ascorbic Acid, Azelaic Acid, Behenyl Alcohol, Bisabolol, Butylene Glycol, Butylene Glycol Dicaprylate Dicaprate, Caprylic Capric Triglyceride, Ceteareth-25, Citric Acid, Cyclomethicone, Di-C12-13 Alkyl Malate, Dimethicone, Disodium Ethylene Dicocamide Peg-15 Disulfate, Ethoxydiglycol, Ethylhexyl Methoxycinnamate, Glycerin, Glyceryl Stearate, Glyceryl Stearate Citrate, Glycyrrhiza Glabra Root Extract, Hydroxypropyl Phosphate Starch, Kojic Acid, Manganese Oxide, Niacinamide, Peg-8 Beeswax, Phenoxyethanol, Phytic Acid, Poloxamer 407, Retinyl Palmitate, Rumex Occidentalis Extract, Salicylic Acid, Sclerotium Gum, Sodium Ascorbyl Phosphate, Sodium Lauroyl Lactylate, Sodium Metabisulfite, Sorbitan Stearate, Stearic Acid, Stearyl Dimethicone, Titanium Dioxide, Tocopherol, Tocopheryl Acetate, Xanthan Gum
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/mesoestetic/cosmelan-2/for/oily-skin
- United Kingdom: https://lovi.care/skincare/uk/p/mesoestetic/cosmelan-2/for/oily-skin
- Ireland: https://lovi.care/skincare/ie/p/mesoestetic/cosmelan-2/for/oily-skin
- Germany: https://lovi.care/skincare/de/p/mesoestetic/cosmelan-2/for/oily-skin
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- Canada: https://lovi.care/skincare/ca/p/mesoestetic/cosmelan-2/for/oily-skin
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- Singapore: https://lovi.care/skincare/sg/p/mesoestetic/cosmelan-2/for/oily-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/mesoestetic/cosmelan-2/for/oily-skin (this page)
- United Arab Emirates: https://lovi.care/skincare/ae/p/mesoestetic/cosmelan-2/for/oily-skin