# Medimine Phyto Enzyme Powder Wash for dry skin

**Lovi Fit: Superior fit for dry skin.**
Dry Skin Fit: High · Effectiveness: High · Safety: Excellent.

Page: https://lovi.care/skincare/sa/p/medimine/phyto-enzyme-powder-wash/for/dry-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Saudi Arabia.

Brand: Medimine
Category: [Exfoliants](https://lovi.care/skincare/sa/best/exfoliators)

This fit is calculated for the concerns frequently associated with dry skin: flakiness, tightness, dehydration, fine lines, and wrinkles. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

One of the best products for dry skin.

## Why this fit

- Offers excellent cleansing and moderate exfoliation for your dry or flaky skin, as papain and sodium cocoyl isethionate gently remove impurities and dead skin cells.
- The inclusion of sorbitol and betaine provides humectant action, while allantoin aids in barrier repair, ensuring your dry skin remains hydrated and supported.
- The product is safe for your dry skin, featuring soothing ingredients like Chamomilla Recutita Flower Extract and Glycyrrhiza Glabra Root Extract with no harsh or prohibited components.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/sa/p/medimine/phyto-enzyme-powder-wash/for/oily-skin): Superior
- [Dry skin](https://lovi.care/skincare/sa/p/medimine/phyto-enzyme-powder-wash/for/dry-skin): Superior (this page)
- [Combination skin](https://lovi.care/skincare/sa/p/medimine/phyto-enzyme-powder-wash/for/combination-skin): High
- [Sensitive skin](https://lovi.care/skincare/sa/p/medimine/phyto-enzyme-powder-wash/for/sensitive-skin): Superior
- [Acne-prone skin](https://lovi.care/skincare/sa/p/medimine/phyto-enzyme-powder-wash/for/acne-prone-skin): Superior
- [Skin with dark spots](https://lovi.care/skincare/sa/p/medimine/phyto-enzyme-powder-wash/for/dark-spots): Superior
- [Mature skin](https://lovi.care/skincare/sa/p/medimine/phyto-enzyme-powder-wash/for/mature-skin): Superior
- [Dry sensitive skin](https://lovi.care/skincare/sa/p/medimine/phyto-enzyme-powder-wash/for/dry-sensitive-skin): Superior
- [Oily acne-prone skin](https://lovi.care/skincare/sa/p/medimine/phyto-enzyme-powder-wash/for/oily-acne-prone-skin): Superior

## Key ingredients

Papain, Pearl Extract, Niacinamide, Licorice Root Extract, Chamomile Flower Extract

## What the research says

- Sodium cocoyl isethionate micelles are too large to penetrate stratum corneum aqueous pores, resulting in significant steric hindrance that prevents skin barrier perturbation and explains its skin mildness. ([Journal of Cosmetic Science, 2007](https://pubmed.ncbi.nlm.nih.gov/17598025/))
- Exogenous sorbitol protected epidermal keratinocytes from osmotic toxicity in vitro and significantly improved skin barrier repair and moisturization in individuals in arid environments. ([Journal of Cosmetic Science, 2013](https://pubmed.ncbi.nlm.nih.gov/23752031/))
- A combination of Aloe barbadensis leaf extract and trimethylglycine in a 1:1 mass ratio synergistically increased aquaporin 3 expression by up to 380% in keratinocytes and safely improved skin hydration in healthy volunteers. ([Molecules, 2024](https://pubmed.ncbi.nlm.nih.gov/38611819/))
- Barley beta-glucan films formulated with sorbitol and acacia gum demonstrated suitable mechanical properties and stimulated in vitro keratinocytes growth. ([International Journal of Pharmaceutics, 2023](https://pubmed.ncbi.nlm.nih.gov/37028573/))
- Topical papain treatment may slightly decrease pain within 30 minutes in humans stung by Chrysaora chinensis compared to placebo. ([Wilderness & Environmental Medicine, 2016](https://pubmed.ncbi.nlm.nih.gov/26827260/))
- A fixed combination of hydroxypinacolone retinoate, retinol glycospheres, and papain glycospheres in aqueous gel applied once daily for 12 weeks achieved a 41% mean reduction in GAGS score and a 40.8% mean reduction in total lesions, with 15.3% of patients experiencing mild to moderate local side effects, in 94 evaluable patients with comedonal-papular, mild to moderate acne of the face. ([Giornale Italiano Di Dermatologia E Venereologia, 2015](https://pubmed.ncbi.nlm.nih.gov/25876142/))
- Reflux extraction of Carica papaya leaves yielded higher antioxidant capacity and superior in vitro wound-healing activities including fibroblast proliferation, cell migration, and collagen synthesis in human skin fibroblasts compared to ultrasonic-assisted extraction and agitation. ([Molecules, 2020](https://pubmed.ncbi.nlm.nih.gov/31991676/))
- Micro and nanosized pearl powders increased skin cell proliferation and migration, accelerated wound closure, enhanced biomechanical strength, improved collagen deposition, and promoted angiogenesis in rats, with nanoscale pearl powder showing the highest efficiency. ([Drug Development and Industrial Pharmacy, 2019](https://pubmed.ncbi.nlm.nih.gov/30950303/))
- Topical pearl extract gel inhibited UV-irritated skin wrinkles, laxity, thickness, and dryness, upregulated antioxidant enzyme activities, decreased MDA levels, and suppressed inflammatory factors in UV-irradiated mice compared to untreated controls, with high-dose PEG showing superior effects to Vitamin E. ([Chemistry & Biodiversity, 2022](https://pubmed.ncbi.nlm.nih.gov/35098641/))
- Seawater pearl powder treatment significantly improves UV-induced photoaging and restores skin tissue structure in mice by reducing MMP-1, enhancing collagen I, inhibiting the MAPK signaling pathway, and scavenging reactive oxygen species. ([Evidence-based Complementary and Alternative Medicine, 2021](https://pubmed.ncbi.nlm.nih.gov/34925534/))
- Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33103316/))
- Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women. ([The Journal of Investigative Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/17882270/))
- Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging. ([Dermatologic Surgery, 2005](https://pubmed.ncbi.nlm.nih.gov/16029679/))
- Combining 755 nm alexandrite laser with topical licorice gel significantly reduces terminal hair counts compared to alexandrite laser with placebo in women with idiopathic hirsutism. ([Evidence-based Complementary and Alternative Medicine, 2015](https://pubmed.ncbi.nlm.nih.gov/26273313/))
- Licochalcone A activated Nrf2 signaling, elevated cytoprotective enzymes, increased the reduced-to-oxidized glutathione ratio, and decreased reactive oxygen species in human fibroblasts and neutrophils, while a LicA-rich licorice extract lowered UVA-induced oxidative processes in vivo. ([Experimental Dermatology, 2015](https://pubmed.ncbi.nlm.nih.gov/25381913/))
- Bioactive glycyrrhizic acid and oxymatrine ionic liquid self-assembled nanomicelles significantly promoted the transdermal permeation, subcutaneous retention, and anti-photoaging efficacy of palmitoyl pentapeptide-4 in cellular and animal models compared to unformulated peptide. ([Advanced Science, 2025](https://pubmed.ncbi.nlm.nih.gov/39783908/))
- Apigenin protects against UVA-induced cytotoxicity and senescence in normal human dermal fibroblasts, decreases MMP-1 expression, and when applied topically as a cream in human subjects, increases dermal density and elasticity while reducing fine wrinkle length, skin evenness, moisture content, and transepidermal water loss compared to control cream. ([International Journal of Molecular Medicine, 2016](https://pubmed.ncbi.nlm.nih.gov/27279007/))
- Topical chamomile oil combined with a night splint significantly improved the symptomatic and functional status of patients with severe carpal tunnel syndrome compared to placebo, while electrodiagnostic parameters showed no significant changes. ([Complementary Therapies in Clinical Practice, 2015](https://pubmed.ncbi.nlm.nih.gov/26573447/))
- German chamomile solution applied twice a day healed peristomal skin lesions significantly faster than once-a-day 1% hydrocortisone ointment in colostomy patients, with a mean healing time of 8.89 days versus 14.53 days. ([Ostomy/wound Management, 2011](https://pubmed.ncbi.nlm.nih.gov/21617262/))

## What reviewers say

Based on limited data, users generally praise this powder wash for its ability to dramatically improve skin texture and brightness without causing tightness, often describing it as a "holy grail" for smoothing rough skin. However, experiences are polarized regarding sensitivity; while many find it gentle, a minority report significant irritation and redness, and some struggle with the powder packaging.

- Liked: Smoothes skin texture (mostly mentioned)
- Liked: Brightening effect (often mentioned)
- Liked: Non-stripping (often mentioned)
- Liked: Clears bumps/acne (sometimes noted)
- Disliked: Packaging issues (sometimes noted)
- Disliked: High price (rarely noted)
- Disliked: Makeup removal (rarely noted)
- Disliked: Potential irritation (rarely noted)

## How to apply

- Use your enzyme powder cleanser as part of your PM routine once a week to start. Carefully increase frequency only if your dry skin tolerates it well.
- Apply this powder cleanser after your regular pre-cleanser and cleanser steps, but before your toner and moisturizer. Follow the weekly routine order for best results.
- Mix a small amount of the enzyme powder cleanser with water in your hands to create a gentle foam. Gently massage the foam onto your face without harsh rubbing.
- Apply the cleanser to slightly damp skin to help activate the enzyme formula smoothly. Rinse thoroughly with lukewarm water afterward.
- Avoid the eye area during application and do a patch test before your first use. Always use SPF the next day since exfoliants can make your skin more sensitive to the sun.
- Video: https://storage.pora.ai/2d8db6e67371d665a6a7736b5ed5d762.mp4

## Questions and answers

### What makes Medimine Phyto Enzyme Powder Wash one of the best fits for dry skin?

Medimine Phyto Enzyme Powder Wash is an exceptional fit for dry skin because it gently cleanses and smooths away flaky skin with papain and mild cleansers. It also keeps your skin soft and well-hydrated with sorbitol and betaine, while soothing ingredients like chamomile and licorice root keep your face calm and supported.
Sources: [Journal of Cosmetic Science, 2013](https://pubmed.ncbi.nlm.nih.gov/23752031/), [Journal of Cosmetic Science, 2007](https://pubmed.ncbi.nlm.nih.gov/17598025/)

### Which ingredients make this cleanser a good fit for dry skin?

Papain and sodium cocoyl isethionate gently remove impurities while sorbitol and betaine hold moisture in dry skin. Allantoin helps repair the skin barrier, and soothing licorice root and chamomile flower extracts keep skin calm.
Sources: [Journal of Cosmetic Science, 2013](https://pubmed.ncbi.nlm.nih.gov/23752031/), [Journal of Cosmetic Science, 2007](https://pubmed.ncbi.nlm.nih.gov/17598025/)

### What does Papain do for dry skin?

Papain helps exfoliate dry skin by breaking down dead surface cells, but it may cause irritation if the skin barrier is already compromised. Products for dry skin need gentle exfoliating enzymes paired with rich moisturizers and barrier-repairing ingredients to keep the skin smooth and comfortable.
Sources: [The Journal of Investigative Dermatology, 2015](https://pubmed.ncbi.nlm.nih.gov/25705851/), [Journal of Cosmetic Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/34897928/)

### What does Pearl Extract do for dry skin?

Pearl extract helps smooth dry skin and supports hydration. Studies show it helps keep skin soft by fighting irritation and dryness caused by the sun.
Sources: [Chemistry & Biodiversity, 2022](https://pubmed.ncbi.nlm.nih.gov/35098641/)

### Where does this cleanser go in a skincare routine for dry skin?

This enzyme powder cleanser goes in the morning and evening routine for dry skin. Start by using it once a week, and if your skin tolerates it well, you can carefully use it more often.

### Can I use this cleanser with retinol, and in what order?

You can use this cleanser with retinol by using the cleanser first in your routine to wash away dirt and dead skin cells, followed by your retinol treatment. This cleanser is unlikely to irritate dry skin because it contains gentle cleaning agents alongside soothing and hydrating ingredients.

### How often should I use this cleanser?

Start by using this cleanser once a week, and if your skin feels comfortable and looks good, you may carefully use it more often. This gentle approach helps clear away dead skin cells without stripping your dry skin of moisture.

### Can this cleanser clog pores, cause breakouts or purging for dry skin?

This cleanser is unlikely to clog pores, cause breakouts, or lead to purging on dry skin. Its gentle cleansing agents wash away impurities safely without disturbing the skin barrier.
Sources: [Journal of Cosmetic Science, 2007](https://pubmed.ncbi.nlm.nih.gov/17598025/)

### Is this cleanser fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for dry skin

- [SRB Stabilized Rice Bran Enzyme Powder Wash](https://lovi.care/skincare/sa/p/srb/stabilized-rice-bran-enzyme-powder-wash/for/dry-skin) — High fit — SAR 213.00 at Amazon
- [TONYMOLY I'm Rice Exfoliating Enzyme Cleanser](https://lovi.care/skincare/sa/p/tonymoly/i-m-rice-exfoliating-enzyme-cleanser/for/dry-skin) — Average fit — SAR 105.68 at Amazon
- [Tatcha The Rice Polish: Gentle](https://lovi.care/skincare/sa/p/tatcha/the-rice-polish-gentle/for/dry-skin) — Average fit — SAR 392.00 at Amazon

## Pairs well with

- Cleanser: [La Roche-Posay Hydrating Gentle Cleanser](https://lovi.care/skincare/sa/p/la-roche-posay/toleriane-hydrating-gentle-cleanser/for/dry-skin) — Superior fit — SAR 297.00 at Amazon
- Moisturizer: [SKIN1004 Madagascar Centella Probio-Cica Enrich Cream](https://lovi.care/skincare/sa/p/skin1004/madagascar-centella-probio-cica-enrich-cream/for/dry-skin) — Superior fit — SAR 48.00 at Amazon
- SPF: [d'Alba Piedmont Waterfull Mild Sunscreen](https://lovi.care/skincare/sa/p/d-alba/piedmont-waterfull-mild-sunscreen/for/dry-skin) — Superior fit — SAR 75.00 at Amazon

## Where to buy

No store in Saudi Arabia has a checked price for this product, so the page shows none.

## Ingredients

Zea Mays Starch, Sodium Cocoyl Isethionate, Sodium Lauroyl Glutamate, Sorbitol, Papain, Pearl Extract, Chamomilla Recutita Flower Extract Matricaria Flower Extract, Glycyrrhiza Glabra Root Extract Licorice Root Extract, Allantoin, Citric Acid, Disodium Edta, Isopropyl Palmitate, Niacinamide, Betaine
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/medimine/phyto-enzyme-powder-wash/for/dry-skin
- United Kingdom: https://lovi.care/skincare/uk/p/medimine/phyto-enzyme-powder-wash/for/dry-skin
- Ireland: https://lovi.care/skincare/ie/p/medimine/phyto-enzyme-powder-wash/for/dry-skin
- Germany: https://lovi.care/skincare/de/p/medimine/phyto-enzyme-powder-wash/for/dry-skin
- France: https://lovi.care/skincare/fr/p/medimine/phyto-enzyme-powder-wash/for/dry-skin
- Italy: https://lovi.care/skincare/it/p/medimine/phyto-enzyme-powder-wash/for/dry-skin
- Netherlands: https://lovi.care/skincare/nl/p/medimine/phyto-enzyme-powder-wash/for/dry-skin
- Spain: https://lovi.care/skincare/es/p/medimine/phyto-enzyme-powder-wash/for/dry-skin
- Canada: https://lovi.care/skincare/ca/p/medimine/phyto-enzyme-powder-wash/for/dry-skin
- Australia: https://lovi.care/skincare/au/p/medimine/phyto-enzyme-powder-wash/for/dry-skin
- Singapore: https://lovi.care/skincare/sg/p/medimine/phyto-enzyme-powder-wash/for/dry-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/medimine/phyto-enzyme-powder-wash/for/dry-skin (this page)
- United Arab Emirates: https://lovi.care/skincare/ae/p/medimine/phyto-enzyme-powder-wash/for/dry-skin