# Medicube Zero Pore One-Day Cream for sensitive skin

**Lovi Fit: Average fit for sensitive skin.**
Normal Skin Fit: High · Effectiveness: Average · Safety: High.

Page: https://lovi.care/skincare/sa/p/medicube/zero-pore-one-day-cream/for/sensitive-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Saudi Arabia.

Brand: [Medicube](https://lovi.care/skincare/sa/brands/medicube)
Category: [Moisturizers and moisturizing serums](https://lovi.care/skincare/sa/best/moisturizers)

This fit is calculated for the concerns frequently associated with sensitive skin: redness, stinging, and reactions to new products. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for sensitive skin; other moisturizers fit it better.

## Why this fit

- Offers moderate benefits for your normal skin, as niacinamide and salicylic acid help regulate sebum and refine texture, while hyaluronic acid and panthenol provide hydration and soothing effects for redness and irritation.
- Witch hazel extract and allantoin further support skin comfort and barrier function, contributing to overall skin health.
- The product is safe for your sensitive skin, with no harsh ingredients and the inclusion of soothing components like panthenol and witch hazel extract.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/sa/p/medicube/zero-pore-one-day-cream/for/oily-skin): High
- [Dry skin](https://lovi.care/skincare/sa/p/medicube/zero-pore-one-day-cream/for/dry-skin): Low
- [Combination skin](https://lovi.care/skincare/sa/p/medicube/zero-pore-one-day-cream/for/combination-skin): High
- [Sensitive skin](https://lovi.care/skincare/sa/p/medicube/zero-pore-one-day-cream/for/sensitive-skin): Average (this page)
- [Acne-prone skin](https://lovi.care/skincare/sa/p/medicube/zero-pore-one-day-cream/for/acne-prone-skin): High
- [Skin with dark spots](https://lovi.care/skincare/sa/p/medicube/zero-pore-one-day-cream/for/dark-spots): High
- [Mature skin](https://lovi.care/skincare/sa/p/medicube/zero-pore-one-day-cream/for/mature-skin): High
- [Dry sensitive skin](https://lovi.care/skincare/sa/p/medicube/zero-pore-one-day-cream/for/dry-sensitive-skin): Low
- [Oily acne-prone skin](https://lovi.care/skincare/sa/p/medicube/zero-pore-one-day-cream/for/oily-acne-prone-skin): High

## Key ingredients

Panthenol, Bha, Glycerin, Niacinamide, Sodium Hyaluronate

## What the research says

- Topical dexpanthenol acts as a moisturizer, improves stratum corneum hydration, accelerates wound healing and epidermal regeneration, reduces erythema, and improves symptoms of skin irritation compared to vehicle or no pretreatment. ([American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/))
- A new topical panthenol-containing emollient significantly improved transepidermal water loss reduction, stratum corneum hydration, and intercellular lipid lamellae length compared with control in healthy subjects without negatively impacting bacterial viability. ([The Journal of Dermatological Treatment, 2017](https://pubmed.ncbi.nlm.nih.gov/27425824/))
- A panthenol-enriched mask significantly decreased erythema and hyperpigmentation, increased sebum and stratum corneum moisture, and reduced transepidermal water loss compared to a saline dressing in 60 subjects undergoing facial laser treatment. ([Journal of Cosmetic Dermatology, 2025](https://pubmed.ncbi.nlm.nih.gov/40613435/))
- Hamamelis bark proanthocyanidins strongly increased the proliferation of cultured human keratinocytes and reduced transepidermal water loss and erythema formation in SLS-irritated skin, whereas the polysaccharide fraction had no effect. ([Phytochemistry, 2001](https://pubmed.ncbi.nlm.nih.gov/11684194/))
- A topical gel containing chitosan, chlorhexidine, allantoin, and dexpanthenol significantly reduced postoperative pain, trismus, swelling, and analgesic consumption, while improving wound healing after third molar surgery compared to a placebo. ([Medicina Oral, Patologia Oral Y Cirugia Bucal, 2020](https://pubmed.ncbi.nlm.nih.gov/32683390/))
- Moisturizer containing 5% panthenol, madecassoside, and copper-zinc-manganese decreased adverse reactions and downtime after ablative fractional carbon dioxide laser resurfacing with comparable efficacy to 0.02% triamcinolone acetonide cream in 20 subjects. ([Journal of Cosmetic Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30945430/))
- Topical dexpanthenol formulated in lipophilic vehicles improved stratum corneum hydration and reduced transepidermal water loss compared to vehicle control in humans. ([Arzneimittel-Forschung, 2000](https://pubmed.ncbi.nlm.nih.gov/10965426/))
- Hyaluronic acid, hyaluronic acid plus dexpanthenol, and isotonic saline nasal sprays all significantly improved dry nose symptoms over four weeks in 240 patients, with hyaluronic acid plus dexpanthenol providing superior nasal moisturisation compared to the other two. ([Auris, Nasus, Larynx, 2020](https://pubmed.ncbi.nlm.nih.gov/32067777/))
- Cryotherapy with liquid nitrogen achieved a higher cure rate (39%) than salicylic acid (24%) and a wait-and-see approach (16%) for cutaneous warts at 13 weeks in primary care patients. ([CMAJ, 2010](https://pubmed.ncbi.nlm.nih.gov/20837684/))
- A moisturizer containing licochalcone A, 1,2-decanediol, L-carnitine, and salicylic acid significantly reduced noninflammatory, inflammatory, and total acne lesion counts compared to a vehicle control in Thai patients during a 12-week maintenance phase. ([BioMed Research International, 2020](https://pubmed.ncbi.nlm.nih.gov/33150170/))
- Treatment with 2% supramolecular salicylic acid hydrogel resulted in a regression and markedly improvement rate of 51.01% compared to 43.10% for Adapaline gel in patients with mild to moderate facial acne vulgaris, showing no significant difference in efficacy. ([Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38590107/))
- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- The emollient V0034CR significantly reduced TEWL compared to vehicle and vehicle plus glycerol, and significantly increased corneometry scores compared to vehicle and vehicle plus petrolatum in healthy volunteers with dry skin, demonstrating combined barrier function improvement from petrolatum and hydration improvement from glycerol. ([Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31532576/))
- Ten days of treatment with a cream containing 20% glycerin significantly increased skin hydration measured by corneometer values in 17 healthy volunteers compared to a placebo cream, but showed no influence on transepidermal water loss or skin sensitivity to an irritating surfactant. ([International Journal of Cosmetic Science, 2001](https://pubmed.ncbi.nlm.nih.gov/18498456/))
- Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33103316/))
- Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women. ([The Journal of Investigative Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/17882270/))
- Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging. ([Dermatologic Surgery, 2005](https://pubmed.ncbi.nlm.nih.gov/16029679/))
- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))

## What reviewers say

Users with oily and combination skin appreciate this cream's lightweight, non-sticky texture that effectively balances moisture and controls sebum. Many report smoother skin texture and a reduction in the appearance of pores over time, though some find the "one-day" pore-shrinking claims to be exaggerated, suggesting it functions better as a daily moisturizer than a rapid treatment.

- Liked: Lightweight texture (often mentioned)
- Disliked: Strong fragrance (often mentioned)
- Liked: Oil control (sometimes noted)
- Liked: Skin smoothing (sometimes noted)
- Disliked: Slow results (sometimes noted)
- Disliked: Unsanitary packaging (sometimes noted)
- Liked: Pore maintenance (rarely noted)
- Disliked: Potential irritation (rarely noted)

## How to apply

- Use this soothing AM and PM routine every day to keep your normal skin calm. Always remember to apply SPF in the morning after your moisturizer.
- Apply your moisturizer after your toner in the morning, and after your serum in the evening. This step locks in hydration and protects your skin.
- Gently press a small amount of the moisturizer evenly across your face. Avoid rubbing to keep your sensitive skin happy and calm.
- You can apply this gentle formula on dry or slightly damp skin for the best comfort. It works wonderfully on clean skin to soothe redness and irritation.
- Do a patch test before your very first use to check your skin's reaction. Avoid getting the product directly into your eyes .
- Video: https://storage.pora.ai/2f72f5d69f07beeafc30237f829efbff.mp4

## Questions and answers

### How well does Zero Pore One-Day Cream work for sensitive skin?

This cream works decently for sensitive skin, helping balance oil and soothe redness with ingredients like panthenol and niacinamide. A moisturizing treatment for this skin needs highly effective soothing components like fermented Centella Asiatica, cica ceramide, and nourishing oils to enhance barrier function and provide deep hydration without any risk of irritation.
Sources: [American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/), [The Journal of Dermatological Treatment, 2017](https://pubmed.ncbi.nlm.nih.gov/27425824/)

### Which ingredients make this cream a good fit for sensitive skin?

Panthenol, glycerin, hyaluronic acid, and allantoin make this cream a good fit for sensitive skin by providing gentle hydration and soothing effects that help calm redness and irritation. To fit sensitive skin even better, a moisturizing treatment needs ingredients like fermented Centella Asiatica, cica ceramide, and nourishing oils to enhance barrier function and deliver deep hydration without feeling heavy.
Sources: [American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/), [The Journal of Dermatological Treatment, 2017](https://pubmed.ncbi.nlm.nih.gov/27425824/)

### What does Panthenol do for sensitive skin?

Panthenol helps calm sensitive skin by reducing redness and irritation while improving hydration and repairing the skin barrier. It is unlikely to cause negative reactions and supports healing for dry or reactive skin.
Sources: [Journal of Cosmetic Dermatology, 2025](https://pubmed.ncbi.nlm.nih.gov/40682399/), [American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/)

### What does Bha do for sensitive skin?

BHA helps keep sensitive or oily skin calm and clear by gently clearing out pores and lowering extra oil without causing a lot of irritation. Clinical studies show that regular use can improve breakouts and keep the skin barrier feeling comfortable.
Sources: [Journal of Cosmetic Dermatology, 2025](https://pubmed.ncbi.nlm.nih.gov/40682377/), [European Review for Medical and Pharmacological Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/26875890/)

### Where does this cream go in a skincare routine for sensitive skin?

This cream goes in the evening routine as a treatment step, used after cleansing and toning and before moisturizing. Sensitive skin needs gentle hydrating ingredients like hyaluronic acid and soothing components like panthenol and allantoin to keep the skin calm and comfortable.
Sources: [American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/), [The Journal of Dermatological Treatment, 2017](https://pubmed.ncbi.nlm.nih.gov/27425824/)

### Can I use this cream with retinol, and in what order?

You can use this cream with retinol by applying your retinol first and following it with this moisturizer to help keep your skin calm and hydrated. Using a supportive moisturizer with ingredients like panthenol and glycerin may also help reduce dryness and irritation while you use retinol.
Sources: [Cutis, 2006](https://pubmed.ncbi.nlm.nih.gov/17121065/), [American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/)

### How often should I use this cream?

This treatment can be used in your evening routine, starting at once a week and slowly increasing the frequency if your skin tolerates it well. Daily application helps improve skin moisture and barrier function, though sensitive skin needs products rich in gentle, calming, and hydrating ingredients.
Sources: [Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/32141711/), [Health Science Reports, 2021](https://pubmed.ncbi.nlm.nih.gov/34141902/)

### Can this cream clog pores, cause breakouts or purging for sensitive skin?

This cream is unlikely to clog pores or cause breakouts for sensitive skin, as it contains ingredients that help regulate oil and keep skin clear. However, a product for sensitive skin needs extra soothing and barrier-protecting ingredients like panthenol and glycerin to prevent any potential irritation.
Sources: [American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/), [The Journal of Dermatological Treatment, 2017](https://pubmed.ncbi.nlm.nih.gov/27425824/)

### Can I use this cream around the eyes or on my body?

You can use this cream on the thin skin around your eyes and on your body, as it has a safe profile and includes soothing panthenol and witch hazel extract that help calm irritation. Sensitive skin of this type needs a gentle, deeply hydrating formula with barrier-supporting ingredients like ceramides and soothing botanical extracts without exfoliating acids.
Sources: [Surgical and Radiologic Anatomy, 2002](https://pubmed.ncbi.nlm.nih.gov/12375070/), [American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/)

### Is this cream fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for sensitive skin

- [SKIN1004 Madagascar Centella Probio-Cica Enrich Cream](https://lovi.care/skincare/sa/p/skin1004/madagascar-centella-probio-cica-enrich-cream/for/sensitive-skin) — Superior fit — SAR 48.00 at Amazon
- [COSRX Advanced Snail 96 Mucin Power Essence](https://lovi.care/skincare/sa/p/cosrx/advanced-snail-96-mucin-power-essence/for/sensitive-skin) — Superior fit — SAR 14.95 at Amazon
- [COSRX Advanced Snail 92 All in One Cream](https://lovi.care/skincare/sa/p/cosrx/advanced-snail-92-all-in-one-cream/for/sensitive-skin) — Superior fit — SAR 79.00 at Amazon

## Pairs well with

- Cleanser: [Fresh Soy Face Cleanser](https://lovi.care/skincare/sa/p/fresh/soy-face-cleanser/for/sensitive-skin) — Superior fit — SAR 191.00 at Amazon
- Soothing Toner: [Clarins Toning Lotion with Camomile](https://lovi.care/skincare/sa/p/clarins/soothing-toning-lotion/for/sensitive-skin) — Superior fit — SAR 141.00 at Amazon
- Moisturizer with Sun Protection: [Bioderma Bioderma Photoderm Mineral SPF 50+](https://lovi.care/skincare/sa/p/bioderma/photoderm-mineral-fluide-spf50/for/sensitive-skin) — Superior fit — SAR 132.22 at Amazon

## Where to buy

- Amazon.sa: SAR 71.59 (https://www.amazon.sa/dp/B0DVN7TWPR?tag=lovisa02-21&linkCode=osi&th=1&psc=1)
Prices checked 6 Nov 2026.

## Ingredients

Water, Glycerin, Witch Hazel Extract, Panthenol, Allantoin, Melaleuca Alternifolia Tree Leaf Extract, Butylene Glycol, 12-Hexanediol, Hyaluronic Acid, Salicylic Acid, Niacinamide, Vitis Vinifera Fruit Extract Grape Fruit Extract, Camellia Sinensis Leaf Extract, Peptides, Sorbitan Olivate, Beta-Glucan
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/medicube/zero-pore-one-day-cream/for/sensitive-skin
- United Kingdom: https://lovi.care/skincare/uk/p/medicube/zero-pore-one-day-cream/for/sensitive-skin
- Ireland: https://lovi.care/skincare/ie/p/medicube/zero-pore-one-day-cream/for/sensitive-skin
- Germany: https://lovi.care/skincare/de/p/medicube/zero-pore-one-day-cream/for/sensitive-skin
- France: https://lovi.care/skincare/fr/p/medicube/zero-pore-one-day-cream/for/sensitive-skin
- Italy: https://lovi.care/skincare/it/p/medicube/zero-pore-one-day-cream/for/sensitive-skin
- Netherlands: https://lovi.care/skincare/nl/p/medicube/zero-pore-one-day-cream/for/sensitive-skin
- Spain: https://lovi.care/skincare/es/p/medicube/zero-pore-one-day-cream/for/sensitive-skin
- Canada: https://lovi.care/skincare/ca/p/medicube/zero-pore-one-day-cream/for/sensitive-skin
- Australia: https://lovi.care/skincare/au/p/medicube/zero-pore-one-day-cream/for/sensitive-skin
- Singapore: https://lovi.care/skincare/sg/p/medicube/zero-pore-one-day-cream/for/sensitive-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/medicube/zero-pore-one-day-cream/for/sensitive-skin (this page)
- United Arab Emirates: https://lovi.care/skincare/ae/p/medicube/zero-pore-one-day-cream/for/sensitive-skin