# Medicube Triple Collagen Serum for dry sensitive skin

**Lovi Fit: Average fit for dry sensitive skin.**
Dry Skin Fit: High · Effectiveness: Average · Safety: Excellent.

Page: https://lovi.care/skincare/sa/p/medicube/triple-collagen-serum/for/dry-sensitive-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Saudi Arabia.

Brand: [Medicube](https://lovi.care/skincare/sa/brands/medicube)
Category: [Serums and treatments](https://lovi.care/skincare/sa/best/serums)

This fit is calculated for the concerns frequently associated with dry sensitive skin: flakiness, tightness, redness, fine lines, and wrinkles. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for dry sensitive skin; other serums fit it better.

## Why this fit

- Offers moderate suitability for your dry skin, as Glycerin and Trehalose provide humectant action to hydrate and support flaky skin, but it lacks sufficient emollient ingredients for optimal results.
- The serum provides excellent plumping and firming benefits due to multiple forms of collagen and hyaluronic acid, which offer general skincare hydration.
- The safety profile is good, with no risks of irritation for your dry and sensitive skin due to the absence of harsh ingredients and the presence of soothing components like Glycerin and Collagen Extract.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/sa/p/medicube/triple-collagen-serum/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/sa/p/medicube/triple-collagen-serum/for/dry-skin): Average
- [Combination skin](https://lovi.care/skincare/sa/p/medicube/triple-collagen-serum/for/combination-skin): High
- [Sensitive skin](https://lovi.care/skincare/sa/p/medicube/triple-collagen-serum/for/sensitive-skin): High
- [Acne-prone skin](https://lovi.care/skincare/sa/p/medicube/triple-collagen-serum/for/acne-prone-skin): High
- [Skin with dark spots](https://lovi.care/skincare/sa/p/medicube/triple-collagen-serum/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/sa/p/medicube/triple-collagen-serum/for/mature-skin): High
- [Dry sensitive skin](https://lovi.care/skincare/sa/p/medicube/triple-collagen-serum/for/dry-sensitive-skin): Average (this page)
- [Oily acne-prone skin](https://lovi.care/skincare/sa/p/medicube/triple-collagen-serum/for/oily-acne-prone-skin): Average

## Key ingredients

Triple Collagen Complex, Sodium Hyaluronate, Niacinamide, Collagen Extract, Adenosine

## What the research says

- Sodium trehalose sulfate decreased transepidermal water loss and increased stratum corneum water content in participants with low stratum corneum water content when applied for 4 weeks compared to placebo. ([Skin Research and Technology, 2024](https://pubmed.ncbi.nlm.nih.gov/38606717/))
- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Topical hyaluronic acid filler serum combined with Botulinum toxin type A lengthened the duration of the toxin's effect in reducing wrinkles compared to Botulinum toxin type A alone. ([Dermatologic Therapy, 2022](https://pubmed.ncbi.nlm.nih.gov/36200921/))
- Both oral and topical collagen supplements help delay the skin aging process by improving moisture, elasticity, and hydration, with no differences arising between the two types of collagen. ([Dermatology Practical & Conceptual, 2022](https://pubmed.ncbi.nlm.nih.gov/35223163/))
- Topical application of TAC/Collagen postbiotics gel improved skin moisture score and inflammation index, and reduced porphyrins and brown spots in 20 volunteers with acne vulgaris. ([Journal of Cosmetic Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/35818134/))
- Topical collagen tripeptide application improved skin wrinkles, elasticity, and density while reducing advanced glycated end products in 22 Asian women over 4 weeks. ([International Journal of Molecular Sciences, 2022](https://pubmed.ncbi.nlm.nih.gov/35163025/))
- Marine collagen extracted from Greenland halibut skin showed a non-cytotoxic effect on fibroblast cells and provided a slight skin hydration effect when incorporated into cosmetic hydrogel formulations at dosages of 0.1, 0.25, and 0.5% in 23 healthy volunteers. ([Marine Drugs, 2023](https://pubmed.ncbi.nlm.nih.gov/36827098/))
- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))
- Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33103316/))
- Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women. ([The Journal of Investigative Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/17882270/))
- Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging. ([Dermatologic Surgery, 2005](https://pubmed.ncbi.nlm.nih.gov/16029679/))
- Topical adenosine treatment significantly increased the anagen hair growth rate and thick hair rate compared to placebo in Japanese women with female pattern hair loss over 12 months. ([The Journal of Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/19239555/))
- Topical application of a disodium adenosine monophosphate-based formulation reduced wrinkles and hyperpigmentation while improving hydration, barrier function, skin lifting, and epidermal turnover in female participants. ([International Journal of Molecular Sciences, 2026](https://pubmed.ncbi.nlm.nih.gov/42278371/))
- Adenosine and cordycepin stimulate the Wnt/beta-catenin signaling pathway through adenosine receptor and PKA activation, promoting cell proliferation, migration, and growth factor secretion in cultured dermal fibroblasts. ([International Journal of Molecular Sciences, 2021](https://pubmed.ncbi.nlm.nih.gov/34070360/))

## Why other serums fit dry sensitive skin better

- Tocopherol succinate-loaded ethosomal gel increased skin deposition, stability, moisture, and mechanical properties in 13 human subjects compared to a control gel over 12 weeks. ([Journal of Cosmetic Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/35274433/))
- In 50 participants with sensitive skin, a Ceramide NP C15-containing emollient improved skin barrier function with a significant reduction in transepidermal water loss and induced modest changes in skin microbiota compared to the vehicle. ([Skin Pharmacology and Physiology, 2026](https://pubmed.ncbi.nlm.nih.gov/41758783/))
- Hydrogels containing vitamin E-loaded nanostructured lipid carriers exhibited better occlusive properties and long-lasting effects, while vitamin E-loaded nanoemulsions performed a faster skin hydration effect and were selected as more attractive for skin application. ([Colloids and Surfaces. B, Biointerfaces, 2019](https://pubmed.ncbi.nlm.nih.gov/30974262/))

## What reviewers say

Users frequently report this serum provides deep hydration, leading to a plumped, radiant complexion often described as 'glass skin'. It is well-loved for its smooth, non-greasy texture and effectiveness in diminishing fine lines, making it a great base for makeup. Some users find the fragrance to be strong and occasionally encounter issues with the packaging.

- Liked: Deep hydration (mostly mentioned)
- Liked: Glow and radiance (often mentioned)
- Liked: Good texture (sometimes noted)
- Liked: Plumping and anti-aging (sometimes noted)
- Disliked: Packaging issues (sometimes noted)
- Disliked: Strong fragrance (sometimes noted)
- Liked: Makeup compatibility (rarely noted)
- Disliked: Skin sensitivity (rarely noted)
- Disliked: Slightly sticky (rarely noted)
- Disliked: Small quantity (rarely noted)

## How to apply

- Use this PM routine for your evening skincare. Start using the serum 3 times a week and increase to daily use if your skin feels comfortable.
- Apply the serum after cleansing and toner, but right before your moisturizer. This step locks in deep hydration for dry skin.
- Gently press 2-3 drops of the serum into your skin using your palms. Let it absorb completely for a minute ⏱ before applying your next product.
- Since your skin is sensitive, apply the serum on completely dry skin for better tolerance and less irritation.
- Avoid the sensitive eye area during application. Always do a patch test before your first use to ensure your skin reacts well.
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### How well does Triple Collagen Serum work for dry sensitive skin?

Medicube Triple Collagen Serum provides moderate hydration for dry sensitive skin using glycerin and trehalose, but it lacks sufficient softening ingredients for optimal results. A product of this type needs rich moisturizing components and barrier-supporting ingredients like ceramides to properly care for dry sensitive skin.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/), [Skin Research and Technology, 2024](https://pubmed.ncbi.nlm.nih.gov/38606717/)

### Which ingredients make this serum a good fit for dry sensitive skin?

Glycerin, trehalose, and multiple forms of collagen and hyaluronic acid make this serum a good fit by hydrating flaky skin and providing plumping benefits. However, because this product only offers moderate suitability for dry skin, a product of this type needs more nourishing, softening ingredients like ceramides and rich oils to lock in moisture and fully support your skin barrier.
Sources: [Skin Research and Technology, 2024](https://pubmed.ncbi.nlm.nih.gov/38606717/), [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### What does Triple Collagen do for dry sensitive skin?

Triple Collagen helps soothe dry sensitive skin by improving hydration, reducing roughness, and calming irritation. It supports the skin barrier to keep moisture locked in and makes the skin feel much softer.
Sources: [International Journal of Cosmetic Science, 2009](https://pubmed.ncbi.nlm.nih.gov/19496838/)

### What does Hyaluronic Acid do for dry sensitive skin?

Hyaluronic acid is a great fit for dry, sensitive skin because it brings a large boost in hydration, making the skin feel soft and smooth while improving barrier function. It helps calm tightness and dryness, and is unlikely to cause irritation.
Sources: [Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/), [Dermatology and Therapy, 2021](https://pubmed.ncbi.nlm.nih.gov/34176098/)

### Where does this serum go in a skincare routine for dry sensitive skin?

This serum goes in your evening routine after your toner and before your moisturizer. To best care for dry skin, a product of this type needs rich smoothing and softening ingredients alongside hydration to keep flaky skin smooth and comfortable.

### Can I use it with retinol, and in what order?

You can use this serum with retinol by applying the serum first to hydrate and soothe your skin, followed by your retinol product. This product works for dry and sensitive skin, but a product of this type needs extra rich, softening ingredients to properly seal in moisture.

### How often should I use this serum?

You can use this serum in the evening as part of your routine. This helps hydrate and firm your dry skin, though this skin type needs extra softening ingredients for the best results.

### Can it clog pores, cause breakouts or purging for dry sensitive skin?

Medicube Triple Collagen Serum is unlikely to clog pores, cause breakouts, or lead to purging for dry and sensitive skin. Its safety profile is good, with no harsh ingredients that typically trigger irritation on sensitive skin.

### Is this serum fragrance-free and alcohol-free?

It contains fragrance (linalool and limonene) and drying alcohol (alcohol denat).

## Alternatives for dry sensitive skin

- [SkinCeuticals C E Ferulic](https://lovi.care/skincare/sa/p/skinceuticals/c-e-ferulic/for/dry-sensitive-skin) — Superior fit — SAR 865.37 at Amazon
- [Paula's Choice RESIST Super Antioxidant Concentrate Serum](https://lovi.care/skincare/sa/p/paula-s-choice/resist-super-antioxidant-concentrate-serum/for/dry-sensitive-skin) — Superior fit — SAR 461.00 at Amazon
- [Beauty of Joseon Propolis + Niacinamide Glow Serum](https://lovi.care/skincare/sa/p/beauty-of-joseon/propolis-niacinamide-glow-serum/for/dry-sensitive-skin) — Superior fit — SAR 226.83 at Amazon

## Pairs well with

- Cleanser: [Illiyoon Ceramide Derma Amino Cleansing Foam](https://lovi.care/skincare/sa/p/illiyoon/ceramide-derma-amino-cleansing-foam/for/dry-sensitive-skin) — Superior fit — SAR 149.44 at Amazon
- Soothing Toner: [Clarins Toning Lotion with Camomile](https://lovi.care/skincare/sa/p/clarins/soothing-toning-lotion/for/dry-sensitive-skin) — Superior fit — SAR 141.00 at Amazon
- Moisturizer with Sun Protection: [d'Alba UVessence Mild Waterfull Sun Cream SPF 50](https://lovi.care/skincare/sa/p/d-alba/uvessence-mild-waterfull-sun-cream-spf-50/for/dry-sensitive-skin) — Superior fit — SAR 89.00 at Amazon

## Where to buy

- Amazon.sa: SAR 49.96 (https://www.amazon.sa/dp/B085VWWJJT?tag=lovisa02-21&linkCode=osi&th=1&psc=1)
Prices checked 5 Nov 2026.

## Ingredients

Water, Glycerin, Butylene Glycol, Cetyl Ethylhexanoate, Niacinamide, Glycereth-26, Alcohol Denat, 1,2-Hexanediol, Trehalose, Carbomer, Cetearyl Olivate, Tromethamine, Sorbitan Olivate, Ethylhexylglycerin, Collagen Extract, Adenosine, Disodium Edta, Atelocollagen, Desamido Collagen, Hydrolyzed Collagen, Sodium Hyaluronate, Water-Soluble Collagen, Sodium Hyaluronate Crosspolymer, Hydrolyzed Sodium Hyaluronate, Hydrolyzed Hyaluronic Acid, Collagen, Collagen Amino Acids, Sodium Acetylated Hyaluronate, Procollagen, Cyclopentasiloxane, Hydroxypropyltrimonium Hyaluronate, Cyclohexasiloxane, Dimethicone, Benzyl Benzoate, Linalool, Limonene
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/medicube/triple-collagen-serum/for/dry-sensitive-skin
- United Kingdom: https://lovi.care/skincare/uk/p/medicube/triple-collagen-serum/for/dry-sensitive-skin
- Ireland: https://lovi.care/skincare/ie/p/medicube/triple-collagen-serum/for/dry-sensitive-skin
- Germany: https://lovi.care/skincare/de/p/medicube/triple-collagen-serum/for/dry-sensitive-skin
- France: https://lovi.care/skincare/fr/p/medicube/triple-collagen-serum/for/dry-sensitive-skin
- Italy: https://lovi.care/skincare/it/p/medicube/triple-collagen-serum/for/dry-sensitive-skin
- Netherlands: https://lovi.care/skincare/nl/p/medicube/triple-collagen-serum/for/dry-sensitive-skin
- Spain: https://lovi.care/skincare/es/p/medicube/triple-collagen-serum/for/dry-sensitive-skin
- Canada: https://lovi.care/skincare/ca/p/medicube/triple-collagen-serum/for/dry-sensitive-skin
- Australia: https://lovi.care/skincare/au/p/medicube/triple-collagen-serum/for/dry-sensitive-skin
- Singapore: https://lovi.care/skincare/sg/p/medicube/triple-collagen-serum/for/dry-sensitive-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/medicube/triple-collagen-serum/for/dry-sensitive-skin (this page)
- United Arab Emirates: https://lovi.care/skincare/ae/p/medicube/triple-collagen-serum/for/dry-sensitive-skin