# Medicube PDRN PINK CICA SOOTHING TONER for mature skin

**Lovi Fit: Average fit for mature skin.**
Normal Skin Fit: High · Effectiveness: Average · Safety: High.

Page: https://lovi.care/skincare/sa/p/medicube/pdrn-pink-cica-soothing-toner/for/mature-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Saudi Arabia.

Brand: [Medicube](https://lovi.care/skincare/sa/brands/medicube)
Category: [Toners](https://lovi.care/skincare/sa/best/toners)

This fit is calculated for the concerns frequently associated with mature skin: fine lines, wrinkles, and loss of firmness. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for mature skin; other toners fit it better.

## Why this fit

- Offers moderate soothing and calming benefits for your normal skin, as Centella Asiatica Extract and Allantoin work to reduce redness and irritation. Glycerin and Hyaluronic Acid provide excellent humectant action, supporting overall skin hydration.
- While beneficial for general hydration and soothing, the formula does not specifically target your concerns of wrinkles and fine lines.
- The product is safe for your normal skin, featuring soothing ingredients like Centella Asiatica Extract and Hyaluronic Acid with no harsh or prohibited components.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/sa/p/medicube/pdrn-pink-cica-soothing-toner/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/sa/p/medicube/pdrn-pink-cica-soothing-toner/for/dry-skin): Average
- [Combination skin](https://lovi.care/skincare/sa/p/medicube/pdrn-pink-cica-soothing-toner/for/combination-skin): High
- [Sensitive skin](https://lovi.care/skincare/sa/p/medicube/pdrn-pink-cica-soothing-toner/for/sensitive-skin): High
- [Acne-prone skin](https://lovi.care/skincare/sa/p/medicube/pdrn-pink-cica-soothing-toner/for/acne-prone-skin): High
- [Skin with dark spots](https://lovi.care/skincare/sa/p/medicube/pdrn-pink-cica-soothing-toner/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/sa/p/medicube/pdrn-pink-cica-soothing-toner/for/mature-skin): Average (this page)
- [Dry sensitive skin](https://lovi.care/skincare/sa/p/medicube/pdrn-pink-cica-soothing-toner/for/dry-sensitive-skin): Average
- [Oily acne-prone skin](https://lovi.care/skincare/sa/p/medicube/pdrn-pink-cica-soothing-toner/for/oily-acne-prone-skin): Average

## Key ingredients

Centella Asiatica Extract, Hyaluronic Acid, Pdrn Polydeoxyribonucleotide

## What the research says

- Cosmetic formulations containing 5% Centella asiatica extract showed the best efficacy in improving skin moisture and decreasing transepidermal water loss, while also exhibiting antiinflammatory properties in 25 volunteers compared to baseline measurements. ([Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/))
- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Topical hyaluronic acid filler serum combined with Botulinum toxin type A lengthened the duration of the toxin's effect in reducing wrinkles compared to Botulinum toxin type A alone. ([Dermatologic Therapy, 2022](https://pubmed.ncbi.nlm.nih.gov/36200921/))
- Topical application of 0.05% w/w ECa 233 gel reduced erythema index by 0.03 U and improved early crusting and general wound appearance compared to placebo in thirty individuals undergoing facial laser resurfacing. ([Journal of Alternative and Complementary Medicine, 2020](https://pubmed.ncbi.nlm.nih.gov/32310680/))
- Moisturizer containing 5% panthenol, madecassoside, and copper-zinc-manganese decreased adverse reactions and downtime after ablative fractional carbon dioxide laser resurfacing with comparable efficacy to 0.02% triamcinolone acetonide cream in 20 subjects. ([Journal of Cosmetic Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30945430/))
- Topical treatment with 5% vitamin C and 0.1% madecassoside significantly improved clinical scores for wrinkles, suppleness, firmness, roughness, and skin hydration, along with functional and structural remodeling of the elastic fiber network in 20 female volunteers with photoaged skin after 6 months compared to baseline. ([Experimental Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/18503551/))
- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))
- Topical application of Low-Peony PDRN enhanced barrier recovery and improved periorbital skin elasticity in human subjects. ([International Journal of Molecular Sciences, 2025](https://pubmed.ncbi.nlm.nih.gov/41516097/))
- Polydeoxyribonucleotide promotes skin regeneration by increasing ERK phosphorylation, collagen accumulation, and cell proliferation and migration in fibroblasts while inhibiting ERK phosphorylation and inflammatory cytokine expression in keratinocytes. ([Molecular Medicine Reports, 2023](https://pubmed.ncbi.nlm.nih.gov/37350391/))
- A topical mixture of polydeoxyribonucleotide, vitamin C, and niacinamide delivered via a microneedling therapy system decreased skin pigmentation and increased skin elasticity by attenuating melanogenesis and the destruction of collagen and elastin fibers in a UV-B-radiated animal model. ([Molecules, 2022](https://pubmed.ncbi.nlm.nih.gov/35209068/))

## Why other toners fit mature skin better

- Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33103316/))
- Adenosine-loaded dissolving microneedle patches showed similar or better efficacy on skin wrinkles, dermal density, elasticity, and hydration compared to adenosine cream in 22 female subjects. ([International Journal of Cosmetic Science, 2018](https://pubmed.ncbi.nlm.nih.gov/29574973/))
- Topical application of 1.0% Lactobacillus ferment from jojoba cake significantly increased skin collagen fluorescence compared to baseline and placebo cream over 56 days in 46 individuals. ([International Journal of Cosmetic Science, 2026](https://pubmed.ncbi.nlm.nih.gov/42698229/))

## What reviewers say

Users with sensitive and acne-prone skin frequently praise this toner for its immediate soothing and redness-reducing effects, often noting a brighter, more even complexion after consistent use. The lightweight, non-sticky texture is a popular choice for oily and combination skin, though some users with dry skin report it lacks sufficient hydration on its own.

- Liked: Lightweight texture (mostly mentioned)
- Liked: Soothing and calming (often mentioned)
- Liked: Barrier support (sometimes noted)
- Liked: Brightening and glow (sometimes noted)
- Disliked: Not hydrating enough (sometimes noted)
- Disliked: Average results (rarely noted)
- Disliked: Expensive for value (rarely noted)
- Disliked: Sensory complaints (rarely noted)

## How to apply

- Could be used as part of your AM or PM routine. Start using it 3 times a week and move to daily use if your skin tolerates it well.
- Apply this soothing toner right after cleansing and before your moisturizer or SPF .
- Gently press 2-3 drops of the soothing toner into your skin and let it absorb for a minute.
- Apply the soothing toner on slightly damp skin to help with better absorption.
- Avoid the sensitive eye area and do a patch test before your very first use .
- Video: https://storage.pora.ai/25abe7eb181ba53153fd15de2058c2a9.mp4

## Questions and answers

### How well does Medicube PDRN Pink Cica Soothing Toner work for mature skin?

Medicube PDRN Pink Cica Soothing Toner works moderately well for mature skin because ingredients like Centella Asiatica Extract and Hyaluronic Acid help keep skin hydrated and calm, though the formula does not specifically target wrinkles and fine lines. A soothing toner for mature skin needs ingredients that actively help smooth fine lines and boost firmness while providing deep hydration.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/), [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/)

### Which ingredients make this toner a good fit for mature skin?

Glycerin and hyaluronic acid make this toner a good fit by providing deep hydration, while centella asiatica extract and allantoin help calm the skin. However, a soothing toner for mature skin also needs ingredients that specifically target wrinkles and fine lines.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/), [Dermatologic Therapy, 2022](https://pubmed.ncbi.nlm.nih.gov/36200921/)

### What does Centella Asiatica Extract do for mature skin?

Centella Asiatica Extract helps mature skin by improving moisture, reducing moisture loss, and supporting collagen production to keep skin firm and smooth. It also provides antioxidant and calming benefits that help protect against everyday stress and visible signs of aging.
Sources: [Scientific Reports, 2021](https://pubmed.ncbi.nlm.nih.gov/34188145/), [International Journal of Molecular Sciences, 2025](https://pubmed.ncbi.nlm.nih.gov/41516082/)

### What does Hyaluronic Acid do for mature skin?

Hyaluronic acid helps mature skin by deeply boosting moisture, improving elasticity, and smoothing the appearance of fine lines and wrinkles. Regular use keeps the skin looking plump and soft while supporting overall firmness and hydration.
Sources: [Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/), [Skin Research and Technology, 2024](https://pubmed.ncbi.nlm.nih.gov/38591218/)

### Where does this toner go in a skincare routine for mature skin?

This toner goes right after cleansing in the morning and evening, helping to boost hydration and calm redness with ingredients like hyaluronic acid and centella asiatica. Mature skin also needs ingredients and products that specifically target wrinkles and fine lines to truly improve firmness and smooth texture.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/), [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/)

### Can I use this toner with retinol, and in what order?

You can use this toner with your retinol, applying the toner right after cleansing to calm and hydrate your skin before putting on your treatment. This product helps support skin comfort, but mature skin needs active ingredients that specifically target wrinkles and fine lines.
Sources: [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/), [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### How often should I use this toner?

You can use this soothing toner daily to help keep your skin calm and hydrated, as it is safe for your skin type. To properly care for mature skin, a product of this type needs added ingredients that specifically target wrinkles and fine lines.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/), [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/)

### Can this toner clog pores, cause breakouts or purging for mature skin?

This toner is unlikely to clog pores or cause breakouts for mature skin, as it features gentle and soothing ingredients like Centella Asiatica Extract and Hyaluronic Acid without any heavy or harsh components. It helps keep skin calm and hydrated, though a product of this type for mature skin also needs ingredients that specifically target wrinkles and fine lines.
Sources: [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/), [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Is this toner fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for mature skin

- [1004 Skin Madagascar Centella Toning Toner](https://lovi.care/skincare/sa/p/1004-skin/madagascar-centella-toning-toner/for/mature-skin) — Superior fit — SAR 42.61 at Amazon
- [Pixi Milky Tonic](https://lovi.care/skincare/sa/p/pixi/milky-tonic/for/mature-skin) — Superior fit — SAR 107.48 at Amazon
- [TIRTIR Milk Skin](https://lovi.care/skincare/sa/p/tirtir/milk-skin/for/mature-skin) — Superior fit — SAR 80.00 at Amazon

## Pairs well with

- Cleanser: [Fresh Soy Face Cleanser](https://lovi.care/skincare/sa/p/fresh/soy-face-cleanser/for/mature-skin) — Superior fit — SAR 191.00 at Amazon
- Moisturizer: [Obagi Hydrate Luxe Moisture-Rich Cream](https://lovi.care/skincare/sa/p/obagi/hydrate-luxe/for/mature-skin) — Superior fit — SAR 329.18 at Amazon
- SPF: [ISDIN Eryfotona Actinica SPF 50+](https://lovi.care/skincare/sa/p/isdin/eryfotona-actinica-spf-50/for/mature-skin) — Superior fit — SAR 429.81 at Amazon

## Where to buy

- Amazon.sa: SAR 57.80 (https://www.amazon.sa/dp/B0DGPWK9H3?tag=lovisa02-21&linkCode=osi&th=1&psc=1)
Prices checked 6 Nov 2026.

## Ingredients

Water, Glycerin, Centella Asiatica Extract, Hyaluronic Acid, Pdrn Polydeoxyribonucleotide, Rosa Damascena Flower Water, Butylene Glycol, 1,2-Hexanediol, Allantoin, Panthenol, Betaine, Dipropylene Glycol, Ethylhexylglycerin, Disodium Edta
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/medicube/pdrn-pink-cica-soothing-toner/for/mature-skin
- United Kingdom: https://lovi.care/skincare/uk/p/medicube/pdrn-pink-cica-soothing-toner/for/mature-skin
- Ireland: https://lovi.care/skincare/ie/p/medicube/pdrn-pink-cica-soothing-toner/for/mature-skin
- Germany: https://lovi.care/skincare/de/p/medicube/pdrn-pink-cica-soothing-toner/for/mature-skin
- France: https://lovi.care/skincare/fr/p/medicube/pdrn-pink-cica-soothing-toner/for/mature-skin
- Italy: https://lovi.care/skincare/it/p/medicube/pdrn-pink-cica-soothing-toner/for/mature-skin
- Netherlands: https://lovi.care/skincare/nl/p/medicube/pdrn-pink-cica-soothing-toner/for/mature-skin
- Spain: https://lovi.care/skincare/es/p/medicube/pdrn-pink-cica-soothing-toner/for/mature-skin
- Canada: https://lovi.care/skincare/ca/p/medicube/pdrn-pink-cica-soothing-toner/for/mature-skin
- Australia: https://lovi.care/skincare/au/p/medicube/pdrn-pink-cica-soothing-toner/for/mature-skin
- Singapore: https://lovi.care/skincare/sg/p/medicube/pdrn-pink-cica-soothing-toner/for/mature-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/medicube/pdrn-pink-cica-soothing-toner/for/mature-skin (this page)
- United Arab Emirates: https://lovi.care/skincare/ae/p/medicube/pdrn-pink-cica-soothing-toner/for/mature-skin