# Medi-Peel Cica Antio Cream for dry sensitive skin

**Lovi Fit: Average fit for dry sensitive skin.**
Dry Skin Fit: Average · Effectiveness: High · Safety: High.

Page: https://lovi.care/skincare/sa/p/medi-peel/cica-antio-cream/for/dry-sensitive-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Saudi Arabia.

Brand: [Medi-Peel](https://lovi.care/skincare/sa/brands/medi-peel)
Category: [Moisturizers and moisturizing serums](https://lovi.care/skincare/sa/best/moisturizers)

This fit is calculated for the concerns frequently associated with dry sensitive skin: flakiness, tightness, redness, fine lines, and wrinkles. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for dry sensitive skin; other moisturizers fit it better.

## Why this fit

- Offers moderate suitability for your dry and sensitive skin, as Glycerin and Sodium Hyaluronate provide hydration, while Centella Asiatica Extract and Licorice Root Extract offer soothing benefits. Niacinamide also helps improve skin tone, but the formula lacks sufficient emollient and occlusive ingredients to fully address dryness.
- The product provides general skincare benefits like hydration and soothing, which are supportive for dry or flaky skin and sensitivity.
- The safety profile is excellent, with no risks of irritation due to the absence of harsh ingredients and the presence of soothing components.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/sa/p/medi-peel/cica-antio-cream/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/sa/p/medi-peel/cica-antio-cream/for/dry-skin): Average
- [Combination skin](https://lovi.care/skincare/sa/p/medi-peel/cica-antio-cream/for/combination-skin): Average
- [Sensitive skin](https://lovi.care/skincare/sa/p/medi-peel/cica-antio-cream/for/sensitive-skin): Average
- [Acne-prone skin](https://lovi.care/skincare/sa/p/medi-peel/cica-antio-cream/for/acne-prone-skin): Average
- [Skin with dark spots](https://lovi.care/skincare/sa/p/medi-peel/cica-antio-cream/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/sa/p/medi-peel/cica-antio-cream/for/mature-skin): Average
- [Dry sensitive skin](https://lovi.care/skincare/sa/p/medi-peel/cica-antio-cream/for/dry-sensitive-skin): Average (this page)
- [Oily acne-prone skin](https://lovi.care/skincare/sa/p/medi-peel/cica-antio-cream/for/oily-acne-prone-skin): Average

## Key ingredients

Centella Asiatica Extract, Niacinamide, Sodium Hyaluronate, Squalane, Ceramide Np

## What the research says

- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Niacinamide significantly decreased hyperpigmentation and increased skin lightness compared with vehicle alone after 4 weeks of use in women by inhibiting melanosome transfer. ([The British Journal of Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12100180/))
- Cosmetic formulations containing 5% Centella asiatica extract showed the best efficacy in improving skin moisture and decreasing transepidermal water loss, while also exhibiting antiinflammatory properties in 25 volunteers compared to baseline measurements. ([Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/))
- Emulsions containing ceramides 1 and 3 improved skin hydration and reduced transepidermal water loss in sodium lauryl sulfate-irritated skin of fifteen healthy Asian women compared to a control emulsion. ([International Journal of Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/18717861/))
- Topical application of 0.05% w/w ECa 233 gel reduced erythema index by 0.03 U and improved early crusting and general wound appearance compared to placebo in thirty individuals undergoing facial laser resurfacing. ([Journal of Alternative and Complementary Medicine, 2020](https://pubmed.ncbi.nlm.nih.gov/32310680/))
- Moisturizer containing 5% panthenol, madecassoside, and copper-zinc-manganese decreased adverse reactions and downtime after ablative fractional carbon dioxide laser resurfacing with comparable efficacy to 0.02% triamcinolone acetonide cream in 20 subjects. ([Journal of Cosmetic Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30945430/))
- Topical treatment with 5% vitamin C and 0.1% madecassoside significantly improved clinical scores for wrinkles, suppleness, firmness, roughness, and skin hydration, along with functional and structural remodeling of the elastic fiber network in 20 female volunteers with photoaged skin after 6 months compared to baseline. ([Experimental Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/18503551/))
- Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33103316/))
- Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women. ([The Journal of Investigative Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/17882270/))
- Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging. ([Dermatologic Surgery, 2005](https://pubmed.ncbi.nlm.nih.gov/16029679/))
- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))
- Squalane at 0.005-0.015% counteracts UVA-induced oxidative stress, inflammation, and collagen metabolism inhibition while stimulating fibroblast migration in human dermal fibroblasts. ([Molecules, 2025](https://pubmed.ncbi.nlm.nih.gov/40363772/))
- Plant-derived squalane protected human dermal fibroblasts against UVA-induced damage by counteracting ROS formation, suppressing apoptosis-related proteins p53, caspase-3, caspase-9, and PARP, and restoring the pro-survival p-Akt/mTOR pathway. ([Antioxidants, 2025](https://pubmed.ncbi.nlm.nih.gov/40722956/))

## Why other moisturizers fit dry sensitive skin better

- Nanoemulsions containing Macadamia integrifolia seed oil successfully enhanced skin hydration and reduced wrinkles in human volunteers, outperforming conventional emulsions in skin hydration enhancement. ([Nanomaterials, 2024](https://pubmed.ncbi.nlm.nih.gov/38668218/))
- Tocopherol succinate-loaded ethosomal gel increased skin deposition, stability, moisture, and mechanical properties in 13 human subjects compared to a control gel over 12 weeks. ([Journal of Cosmetic Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/35274433/))

## What reviewers say

This cream is widely praised as a rescue treatment for damaged skin barriers, effectively calming redness and inflammation associated with acne and sensitivity. While many users with dry or combination skin love its deep hydration and healing properties, those with very oily skin sometimes find the texture too heavy or occlusive, occasionally leading to clogged pores.

- Liked: Soothes redness (mostly mentioned)
- Liked: Deep hydration (often mentioned)
- Disliked: Poor packaging (often mentioned)
- Liked: Improves acne (sometimes noted)
- Liked: Pleasant texture (sometimes noted)
- Disliked: Sticky/heavy finish (sometimes noted)
- Disliked: Caused breakouts (rarely noted)
- Disliked: Ineffective for some (rarely noted)

## How to apply

- Could be used as part of your AM or PM routine. Start using this moisturizer 3 times a week and move to daily use if your dry skin tolerates it well.
- Apply this moisturizer after cleansing and toner in the morning, or after your serum in the evening. Always pair it with SPF in the morning.
- Gently press a small amount of the moisturizer into your skin. Avoid rubbing it harshly to protect your sensitive skin.
- Apply the moisturizer on slightly damp skin to help with hydration absorption. This also works well for dry and flaky skin types.
- Do a patch test before your first use. Avoid the eye area to prevent any irritation.
- Video: https://storage.pora.ai/2f72f5d69f07beeafc30237f829efbff.mp4

## Questions and answers

### How well does Medi-Peel Cica Antio work for dry sensitive skin?

Medi-Peel Cica Antio Cream works moderately well for dry sensitive skin, offering hydration and calming benefits, though it lacks enough rich moisturizing and sealing ingredients to fully address dryness. A product for this skin needs plenty of nourishing emollients and moisture-locking ingredients to keep dry skin soft and support the skin barrier.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/), [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/)

### Which ingredients make this cream a good fit for dry sensitive skin?

Glycerin and sodium hyaluronate draw in hydration while centella asiatica extract and licorice root extract help calm dry and sensitive skin. To truly fit dry sensitive skin, this type of product needs rich moisturizing oils and protective sealing ingredients to lock in moisture and fully support the skin barrier.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/), [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/)

### What does Centella Asiatica Extract do for dry sensitive skin?

Centella asiatica extract helps calm dry sensitive skin by reducing irritation and improving moisture while protecting the skin barrier. Clinical studies show that regular use noticeably decreases redness and discomfort while keeping the skin soft and hydrated.
Sources: [Journal of Cosmetic Dermatology, 2025](https://pubmed.ncbi.nlm.nih.gov/40682399/), [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/)

### What does Niacinamide do for dry sensitive skin?

Niacinamide helps dry sensitive skin by calming irritation and keeping moisture locked in so your face feels soft and smooth. It works to build up your skin barrier and calm redness while being very gentle and unlikely to cause irritation.
Sources: [Journal of Cosmetic Dermatology, 2004](https://pubmed.ncbi.nlm.nih.gov/17147561/), [International Journal of Pharmaceutics, 2013](https://pubmed.ncbi.nlm.nih.gov/23220080/)

### Where does this cream go in a skincare routine for dry sensitive skin?

This moisturizing treatment goes in the evening routine after your soothing toner and before your moisturizer. For dry sensitive skin, this product needs richer sealing ingredients and heavy softeners to lock in moisture and fully prevent dryness.

### Can I use it with retinol, and in what order?

You can use this treatment with retinol, applying it before your retinol step to help keep your skin calm while it adjusts. A product of this type works best for dry sensitive skin when it includes rich, protective ingredients that lock in moisture and fully prevent dryness.

### How often should I use this cream?

You can use this moisturizing treatment daily to help keep your skin hydrated and calm, though a product of this type for dry sensitive skin ultimately needs richer moisturizing oils and protective butters to fully lock in moisture.
Sources: [Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/32141711/), [Health Science Reports, 2021](https://pubmed.ncbi.nlm.nih.gov/34141902/)

### Can it clog pores, cause breakouts or purging for dry sensitive skin?

Medi-Peel Cica Antio Cream is unlikely to clog pores or cause breakouts for dry sensitive skin, as its safety profile is excellent and harsh ingredients are absent. Reviewers rarely report breakouts, and soothing components like Centella Asiatica Extract help calm the skin.
Sources: [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/)

### Can I use this cream around the eyes or on my body?

You can use this moisturizing treatment around the eyes and on the body, as its excellent safety profile is gentle on thin and delicate areas. However, for dry and sensitive skin, this product type needs richer smoothing and sealing ingredients to fully lock in moisture.

### Is it fragrance-free and alcohol-free?

It has no drying alcohol and contains fragrance (hexyl cinnamal, limonene, linalool, and citronellol). Cetearyl alcohol is a fatty alcohol, which soften the skin.

## Alternatives for dry sensitive skin

- [SKIN1004 Madagascar Centella Probio-Cica Enrich Cream](https://lovi.care/skincare/sa/p/skin1004/madagascar-centella-probio-cica-enrich-cream/for/dry-sensitive-skin) — Superior fit — SAR 48.00 at Amazon
- [Obagi Hydrate Luxe Moisture-Rich Cream](https://lovi.care/skincare/sa/p/obagi/hydrate-luxe/for/dry-sensitive-skin) — Superior fit — SAR 329.18 at Amazon
- [L'Occitane Immortelle Divine Cream](https://lovi.care/skincare/sa/p/l-occitane/immortelle-divine-cream/for/dry-sensitive-skin) — Superior fit — SAR 540.00 at Amazon

## Pairs well with

- Cleanser: [Illiyoon Ceramide Derma Amino Cleansing Foam](https://lovi.care/skincare/sa/p/illiyoon/ceramide-derma-amino-cleansing-foam/for/dry-sensitive-skin) — Superior fit — SAR 149.44 at Amazon
- Soothing Toner: [Clarins Toning Lotion with Camomile](https://lovi.care/skincare/sa/p/clarins/soothing-toning-lotion/for/dry-sensitive-skin) — Superior fit — SAR 141.00 at Amazon
- Moisturizer with Sun Protection: [d'Alba UVessence Mild Waterfull Sun Cream SPF 50](https://lovi.care/skincare/sa/p/d-alba/uvessence-mild-waterfull-sun-cream-spf-50/for/dry-sensitive-skin) — Superior fit — SAR 89.00 at Amazon

## Where to buy

No store in Saudi Arabia has a checked price for this product, so the page shows none.

## Ingredients

Water, Glycerin, Caprylic Capric Triglyceride, Cetearyl Alcohol, Dipropylene Glycol, Niacinamide, Glyceryl Stearate, Peg-100 Stearate, Betaine, Sorbitan Stearate, Arginine, Carbomer, Hydroxyacetophenone, Dimethicone, Caprylyl Glycol, Melia Azadirachta Leaf Extract, Dipotassium Glycyrrhizate, Wheat Extract Sprout, Centella Asiatica Extract, Melia Azadirachta Flower Extract, Coccinia Indica Fruit Extract, Ethylhexylglycerin, Curcuma Longa Root Extract, Eclipta Prostrata Extract, Adenosine, Corallina Officinalis Extract, Ocimum Sanctum Leaf Extract, Glyceryl Acrylate Acrylic Acid Copolymer, Solanum Melongena Fruit Extract, Disodium Edta, Allantoin, Aloe Barbadensis Flower Extract, Tocopheryl Acetate, Panthenol, Propylene Glycol, Propanediol, Beta-Glucan, Squalane, Palmitoyl Tetrapeptide-7, Palmitoyl Tripeptide-1, Fructan, Butylene Glycol, Sodium Hyaluronate Crosspolymer, Glyceryl Polymethacrylate, Sodium Hyaluronate, Hydrolyzed Glycosaminoglycans, Butyrospermum Parkii Butter Shea Butter, 1,2-Hexanediol, Olea Europaea Leaf Extract Olive Leaf Extract, Mannan, Glycyrrhiza Glabra Root Extract Licorice Root Extract, Dandelion Leaf Extract, Benzyl Glycol, Ceramide Np, Phytosphingosine, Hydrolyzed Hyaluronic Acid, Rosa Damascena Flower Extract, Rhodiola Rosea Root Extract, Origanum Vulgare Leaf Extract, Palmitoyl Tripeptide-5, Chamaecyparis Obtusa Leaf Extract, Willow Bark Extract, Usnea Barbata Extract, Zanthoxylum Piperitum Fruit Extract, Pulsatilla Koreana Extract, Lactobacillus Soybean Extract Ferment, Portulaca Oleracea Extract, Citric Acid, Cinnamomum Cassia Bark Extract, Scutellaria Baicalensis Root Extract, Raspberry Ketone, Acetyl Hexapeptide-8, Copper Tripeptide-1, Oligopeptide-29, Oligopeptide-32, Palmitoyl Oligopeptide, Palmitoyl Pentapeptide-4, Hexyl Cinnamal, Limonene, Linalool, Citronellol
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/medi-peel/cica-antio-cream/for/dry-sensitive-skin
- United Kingdom: https://lovi.care/skincare/uk/p/medi-peel/cica-antio-cream/for/dry-sensitive-skin
- Ireland: https://lovi.care/skincare/ie/p/medi-peel/cica-antio-cream/for/dry-sensitive-skin
- Germany: https://lovi.care/skincare/de/p/medi-peel/cica-antio-cream/for/dry-sensitive-skin
- France: https://lovi.care/skincare/fr/p/medi-peel/cica-antio-cream/for/dry-sensitive-skin
- Italy: https://lovi.care/skincare/it/p/medi-peel/cica-antio-cream/for/dry-sensitive-skin
- Netherlands: https://lovi.care/skincare/nl/p/medi-peel/cica-antio-cream/for/dry-sensitive-skin
- Spain: https://lovi.care/skincare/es/p/medi-peel/cica-antio-cream/for/dry-sensitive-skin
- Canada: https://lovi.care/skincare/ca/p/medi-peel/cica-antio-cream/for/dry-sensitive-skin
- Australia: https://lovi.care/skincare/au/p/medi-peel/cica-antio-cream/for/dry-sensitive-skin
- Singapore: https://lovi.care/skincare/sg/p/medi-peel/cica-antio-cream/for/dry-sensitive-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/medi-peel/cica-antio-cream/for/dry-sensitive-skin (this page)
- United Arab Emirates: https://lovi.care/skincare/ae/p/medi-peel/cica-antio-cream/for/dry-sensitive-skin