# Jole Azelaic Acid 10% Serum for mature skin

**Lovi Fit: Average fit for mature skin.**
Normal Skin Fit: High · Effectiveness: Average · Safety: High.

Page: https://lovi.care/skincare/sa/p/jole/azelaic-acid-10-serum/for/mature-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Saudi Arabia.

Brand: [Jole](https://lovi.care/skincare/sa/brands/jole)
Category: [Serums and treatments](https://lovi.care/skincare/sa/best/serums)

This fit is calculated for the concerns frequently associated with mature skin: fine lines, wrinkles, and loss of firmness. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for mature skin; other serums fit it better.

## Why this fit

- Offers moderate treatment for acne-prone skin due to the presence of azelaic acid in a 10% concentration for reducing acne lesions and blemishes, and niacinamide for its anti-inflammatory and melanogenesis regulation properties, which is highly suitable for your normal skin.
- Provides general skincare benefits, such as hydration and soothing, due to ingredients like allantoin and bisabolol, which are supportive but not targeted for your main goal of wrinkles and fine lines.
- The product is safe for your normal skin due to the absence of prohibited or harsh ingredients, posing no risks of irritation.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/sa/p/jole/azelaic-acid-10-serum/for/oily-skin): High
- [Dry skin](https://lovi.care/skincare/sa/p/jole/azelaic-acid-10-serum/for/dry-skin): Average
- [Combination skin](https://lovi.care/skincare/sa/p/jole/azelaic-acid-10-serum/for/combination-skin): High
- [Sensitive skin](https://lovi.care/skincare/sa/p/jole/azelaic-acid-10-serum/for/sensitive-skin): High
- [Acne-prone skin](https://lovi.care/skincare/sa/p/jole/azelaic-acid-10-serum/for/acne-prone-skin): High
- [Skin with dark spots](https://lovi.care/skincare/sa/p/jole/azelaic-acid-10-serum/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/sa/p/jole/azelaic-acid-10-serum/for/mature-skin): Average (this page)
- [Dry sensitive skin](https://lovi.care/skincare/sa/p/jole/azelaic-acid-10-serum/for/dry-sensitive-skin): Average
- [Oily acne-prone skin](https://lovi.care/skincare/sa/p/jole/azelaic-acid-10-serum/for/oily-acne-prone-skin): High

## Key ingredients

Azelaic Acid, Niacinamide, Squalane, Bisabolol, Allantoin

## What the research says

- Niacinamide significantly decreased hyperpigmentation and increased skin lightness compared with vehicle alone after 4 weeks of use in women by inhibiting melanosome transfer. ([The British Journal of Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12100180/))
- Azelaic acid nanocrystal hydrogel 10% achieved a higher success rate and greater lesion reduction than azelaic acid cream 20% in patients with mild to moderate facial acne. ([Pharmaceutics, 2021](https://pubmed.ncbi.nlm.nih.gov/33923739/))
- Application of 15% azelaic acid gel significantly reduced post-inflammatory erythema and hyperpigmentation, decreased hemoglobin and melanin content, improved quality of life, and contributed to acne improvement in patients with mild to moderate acne compared to placebo. ([Dermatology and Therapy, 2024](https://pubmed.ncbi.nlm.nih.gov/38734843/))
- A topical gel containing chitosan, chlorhexidine, allantoin, and dexpanthenol significantly reduced postoperative pain, trismus, swelling, and analgesic consumption, while improving wound healing after third molar surgery compared to a placebo. ([Medicina Oral, Patologia Oral Y Cirugia Bucal, 2020](https://pubmed.ncbi.nlm.nih.gov/32683390/))
- Topical application of a dermocosmetic containing Myrtus communis extract and azelaic acid reduced acne relapses and helped maintain remission compared to a light moisturizing cream in adult females in the acne maintenance phase over 16 weeks. ([Journal of the European Academy of Dermatology and Venereology, 2023](https://pubmed.ncbi.nlm.nih.gov/36729399/))
- Topical administration of 20% azelaic acid cream and 5% tranexamic acid solution comparably improved acne-related postinflammatory hyperpigmentation in patients with acne vulgaris, while tranexamic acid demonstrated a significantly better safety profile at week 4. ([Journal of Research in Medical Sciences, 2023](https://pubmed.ncbi.nlm.nih.gov/37213446/))
- Azelaic acid 15% gel showed comparable efficacy to adapalene 0.1% gel in reducing lesions, severity, and Dermatology Life Quality Index in women with adult acne, with significantly lower dryness and scaling, and demonstrated superiority during maintenance compared to no further treatment. ([Journal of the European Academy of Dermatology and Venereology, 2015](https://pubmed.ncbi.nlm.nih.gov/25399481/))
- Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33103316/))
- Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women. ([The Journal of Investigative Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/17882270/))
- Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging. ([Dermatologic Surgery, 2005](https://pubmed.ncbi.nlm.nih.gov/16029679/))
- Squalane at 0.005-0.015% counteracts UVA-induced oxidative stress, inflammation, and collagen metabolism inhibition while stimulating fibroblast migration in human dermal fibroblasts. ([Molecules, 2025](https://pubmed.ncbi.nlm.nih.gov/40363772/))
- Plant-derived squalane protected human dermal fibroblasts against UVA-induced damage by counteracting ROS formation, suppressing apoptosis-related proteins p53, caspase-3, caspase-9, and PARP, and restoring the pro-survival p-Akt/mTOR pathway. ([Antioxidants, 2025](https://pubmed.ncbi.nlm.nih.gov/40722956/))
- Application of an alpha-bisabolol-containing cream produced a significant skin-lightening effect in pigmented skin compared to a vehicle control in the majority of female subjects after 8 weeks. ([International Journal of Cosmetic Science, 2010](https://pubmed.ncbi.nlm.nih.gov/20642768/))
- The combination of allantoin, bisabolol, D-panthenol and dipotassium glycyrrhizinate reduces UVB-induced PGE2, inflammatory cytokines, and mitochondrial superoxide in human epidermal keratinocytes. ([International Journal of Cosmetic Science, 2024](https://pubmed.ncbi.nlm.nih.gov/38433250/))
- Topical gel containing chitosan, 0.2% chlorhexidine, allantoin and dexpanthenol did not improve postoperative comfort regarding swelling and pain, but improved the wound's aesthetic appearance following impacted lower third molar extraction compared to no gel. ([Medicina Oral, Patologia Oral Y Cirugia Bucal, 2016](https://pubmed.ncbi.nlm.nih.gov/27475700/))
- An overnight patch containing Allium cepa extract and allantoin safely promotes scar healing after dermatologic surgery, resulting in significantly greater reductions in observer- and patient-assessed POSAS scores compared to no treatment. ([Aesthetic Plastic Surgery, 2018](https://pubmed.ncbi.nlm.nih.gov/29948103/))
- Prophylactic application of a topical scar gel containing Allium cepae extract, allantoin, and heparin significantly improves patient-assessed scar color, stiffness, and irregularity compared to no treatment in women following a cesarean section. ([Journal of Drugs in Dermatology, 2014](https://pubmed.ncbi.nlm.nih.gov/24509969/))

## Why other serums fit mature skin better

- Caviar oil enhanced adipocyte differentiation in vitro, reduced MMP expression while increasing collagen and elastin formation ex vivo, and improved skin moisture, elasticity, and density in 102 participants over four weeks of Cavi Balm usage compared to baseline. ([In Vivo, 2023](https://pubmed.ncbi.nlm.nih.gov/37652485/))
- Chronomodulated daytime application of baicalin and nighttime application of palmitoyl tripeptide-1 synergistically improved skin luminance by 16.29%, nasolabial fold depth by -36.35%, and firmness by 24.35% in 30 female participants. ([Journal of Cosmetic Dermatology, 2026](https://pubmed.ncbi.nlm.nih.gov/41527525/))
- A topical serum containing vitamin C, vitamin E, and raspberry leaf cell culture extract improved skin color, elasticity, radiance, smoothness, scaliness, and wrinkles compared to the untreated contralateral side in fifty female volunteers. ([Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31975502/))

## What reviewers say

Users highly recommend this serum for acne-prone and sensitive skin, noting its strong effectiveness in clearing active breakouts, reducing inflammation, and fading post-acne hyperpigmentation. The lightweight formula absorbs quickly and improves overall skin texture, though a small number of users experienced temporary dryness or a brief purging phase.

- Liked: Reduces acne breakouts (mostly mentioned)
- Liked: Fades post-acne marks (often mentioned)
- Liked: Absorbs very quickly (sometimes noted)
- Liked: Calms skin redness (sometimes noted)
- Disliked: Causes mild dryness (rarely noted)
- Disliked: Faulty pump dispenser (rarely noted)
- Disliked: Initial skin purging (rarely noted)

## How to apply

- Use this serum in your PM routine. Start by applying it 3 times a week, and work up to daily use if your skin likes it.
- Apply this serum after your toner and before your moisturizer.
- Gently press 2-3 drops of the serum into your skin and let it absorb for a minute.
- You can apply the serum on dry skin for the best results against fine lines.
- Always do a patch test before your first use and avoid the sensitive eye area.
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### How well does Jole Jole Azelaic Acid 10% Serum work for mature skin?

Jole Jole Azelaic Acid 10% Serum is an average fit for mature skin because, while it provides general hydration and soothing, it lacks targeted ingredients for fine lines and wrinkles. Mature skin needs products with powerful antioxidants, peptides, and hydrating ingredients to effectively improve skin elasticity, smooth lines, and keep the skin looking youthful.
Sources: [The British Journal of Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12100180/), [Pharmaceutics, 2021](https://pubmed.ncbi.nlm.nih.gov/33923739/)

### Which ingredients make this serum a good fit for mature skin?

This serum works for mature skin because it includes niacinamide and azelaic acid, which help even out skin tone. To better care for mature skin, a product of this type needs high concentrations of potent antioxidants, peptides, and humectants that specifically target wrinkles and fine lines while improving skin elasticity and moisture retention.
Sources: [The British Journal of Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12100180/)

### What does Azelaic Acid do for mature skin?

Azelaic acid helps mature skin by targeting dark spots and uneven tone, while supporting smoother texture and a more youthful look. It provides antioxidant benefits that may reduce signs of aging and protect skin from environmental stress.
Sources: [Frontiers in Medicine, 2026](https://pubmed.ncbi.nlm.nih.gov/42023095/), [Journal of Cosmetic Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/36056802/)

### What does Niacinamide do for mature skin?

Niacinamide helps mature skin by smoothing out fine lines and wrinkles, reducing dark spots, and improving overall skin elasticity. It is also very well tolerated and supports a strong skin barrier to keep skin looking healthy.
Sources: [Antioxidants, 2021](https://pubmed.ncbi.nlm.nih.gov/34439563/), [Journal of Cosmetic Dermatology, 2004](https://pubmed.ncbi.nlm.nih.gov/17147561/)

### Where does this serum go in a skincare routine for mature skin?

This serum goes in the evening routine after cleansing and toning, as treatments with active ingredients are typically used then for simplicity and extra safety around sun exposure. Mature skin seeking help for wrinkles and fine lines needs products of this type that include targeted anti-aging ingredients like retinoids, peptides, or antioxidants.

### Can I use this serum with retinol, and in what order?

You can use this serum with retinol, but apply them on alternating nights to keep your skin calm and avoid irritation. When used together in a routine, a treatment for mature skin needs ingredients like peptides, retinol, and antioxidants to target wrinkles and fine lines.

### How often should I use this serum?

This serum is used in the evening once a week to start, since routines start treatments cautiously. Mature skin needs targeted anti-aging ingredients like retinoids, peptides, or antioxidants to smooth fine lines and wrinkles.

### Can this serum clog pores, cause breakouts or purging for mature skin?

This serum is unlikely to clog pores, but initial skin purging may rarely happen when you start using it. Reviewers report only low chances of mild dryness or purging, and it is safe for your skin.

### Is this serum fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for mature skin

- [Paula's Choice RESIST Super Antioxidant Concentrate Serum](https://lovi.care/skincare/sa/p/paula-s-choice/resist-super-antioxidant-concentrate-serum/for/mature-skin) — Superior fit — SAR 461.00 at Amazon
- [SkinCeuticals C E Ferulic](https://lovi.care/skincare/sa/p/skinceuticals/c-e-ferulic/for/mature-skin) — Superior fit — SAR 865.37 at Amazon
- [La Prairie Skin Caviar Liquid Lift](https://lovi.care/skincare/sa/p/la-prairie/skin-caviar-liquid-lift/for/mature-skin) — High fit — SAR 5,271.00 at Amazon

## Pairs well with

- Cleanser: [Fresh Soy Face Cleanser](https://lovi.care/skincare/sa/p/fresh/soy-face-cleanser/for/mature-skin) — Superior fit — SAR 191.00 at Amazon
- Hydrating Toner: [COSRX Propolis Synergy Toner](https://lovi.care/skincare/sa/p/cosrx/full-fit-propolis-synergy-toner/for/mature-skin) — Superior fit — SAR 30.00 at Amazon
- Moisturizer: [Obagi Hydrate Luxe Moisture-Rich Cream](https://lovi.care/skincare/sa/p/obagi/hydrate-luxe/for/mature-skin) — Superior fit — SAR 329.18 at Amazon

## Where to buy

No store in Saudi Arabia has a checked price for this product, so the page shows none.

## Ingredients

Water, Ethoxydiglycol, Azelaic Acid, Niacinamide, Glyceryl Glucoside, Squalane, Bisabolol, Allantoin, Ammonium Acryloyldimethyltaurate Vp Copolymer, Valine, Proline, Lysine, Serine, Sorbitan Caprylate, 1,2 Propanediol, Benzoic Acid
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/jole/azelaic-acid-10-serum/for/mature-skin
- United Kingdom: https://lovi.care/skincare/uk/p/jole/azelaic-acid-10-serum/for/mature-skin
- Ireland: https://lovi.care/skincare/ie/p/jole/azelaic-acid-10-serum/for/mature-skin
- Germany: https://lovi.care/skincare/de/p/jole/azelaic-acid-10-serum/for/mature-skin
- France: https://lovi.care/skincare/fr/p/jole/azelaic-acid-10-serum/for/mature-skin
- Italy: https://lovi.care/skincare/it/p/jole/azelaic-acid-10-serum/for/mature-skin
- Netherlands: https://lovi.care/skincare/nl/p/jole/azelaic-acid-10-serum/for/mature-skin
- Spain: https://lovi.care/skincare/es/p/jole/azelaic-acid-10-serum/for/mature-skin
- Canada: https://lovi.care/skincare/ca/p/jole/azelaic-acid-10-serum/for/mature-skin
- Australia: https://lovi.care/skincare/au/p/jole/azelaic-acid-10-serum/for/mature-skin
- Singapore: https://lovi.care/skincare/sg/p/jole/azelaic-acid-10-serum/for/mature-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/jole/azelaic-acid-10-serum/for/mature-skin (this page)
- United Arab Emirates: https://lovi.care/skincare/ae/p/jole/azelaic-acid-10-serum/for/mature-skin