# Centellian24 Madeca Cream for acne-prone skin

**Lovi Fit: High fit for acne-prone skin.**
Combination Skin Fit: High · Effectiveness: High · Safety: High.

Page: https://lovi.care/skincare/sa/p/centellian24/madeca-cream/for/acne-prone-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Saudi Arabia.

Brand: [Centellian24](https://lovi.care/skincare/sa/brands/centellian24)
Category: [Moisturizers and moisturizing serums](https://lovi.care/skincare/sa/best/moisturizers)

This fit is calculated for the concerns frequently associated with acne-prone skin: breakouts, blackheads, and post-acne marks. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

A great choice for acne-prone skin; a few moisturizers fit it even better.

## Why this fit

- Highly suitable for your combination skin, the Centella Asiatica Extract and Niacinamide work synergistically to soothe inflammation and regulate sebum production, directly addressing your acne, blemishes, and breakouts.
- The inclusion of Madecassic Acid further enhances texture smoothing and hydration, complementing the anti-inflammatory benefits for your skin.
- The product is safe for your acne-prone skin, featuring soothing ingredients like Centella Asiatica Extract and Allantoin with no harsh or prohibited substances.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/sa/p/centellian24/madeca-cream/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/sa/p/centellian24/madeca-cream/for/dry-skin): High
- [Combination skin](https://lovi.care/skincare/sa/p/centellian24/madeca-cream/for/combination-skin): Average
- [Sensitive skin](https://lovi.care/skincare/sa/p/centellian24/madeca-cream/for/sensitive-skin): High
- [Acne-prone skin](https://lovi.care/skincare/sa/p/centellian24/madeca-cream/for/acne-prone-skin): High (this page)
- [Skin with dark spots](https://lovi.care/skincare/sa/p/centellian24/madeca-cream/for/dark-spots): High
- [Mature skin](https://lovi.care/skincare/sa/p/centellian24/madeca-cream/for/mature-skin): High
- [Dry sensitive skin](https://lovi.care/skincare/sa/p/centellian24/madeca-cream/for/dry-sensitive-skin): High
- [Oily acne-prone skin](https://lovi.care/skincare/sa/p/centellian24/madeca-cream/for/oily-acne-prone-skin): High

## Key ingredients

Centella Asiatica, Madecassoside, Teca Extract Titrated Of Centella Asiatica Extract, Niacinamide, Sodium Hyaluronate

## What the research says

- Co-delivery of paeonol and madecassoside via nanoemulsions improved transdermal delivery, promoted barrier repair proteins, inhibited inflammatory cytokine secretion in cellular and 3D models, and reduced transepidermal water loss and acne in human facial skin compared to free components. ([Molecules, 2023](https://pubmed.ncbi.nlm.nih.gov/37446936/))
- Cosmetic formulations containing 5% Centella asiatica extract showed the best efficacy in improving skin moisture and decreasing transepidermal water loss, while also exhibiting antiinflammatory properties in 25 volunteers compared to baseline measurements. ([Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/))
- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Topical application of 0.05% w/w ECa 233 gel reduced erythema index by 0.03 U and improved early crusting and general wound appearance compared to placebo in thirty individuals undergoing facial laser resurfacing. ([Journal of Alternative and Complementary Medicine, 2020](https://pubmed.ncbi.nlm.nih.gov/32310680/))
- Chitosan-based hydrogels loaded with asiaticoside-rich Centella asiatica extract achieved controlled drug release, skin permeability, antimicrobial activity, and synergistic wound healing effects in an in vitro model. ([International Journal of Molecular Sciences, 2023](https://pubmed.ncbi.nlm.nih.gov/38139059/))
- Moisturizer containing 5% panthenol, madecassoside, and copper-zinc-manganese decreased adverse reactions and downtime after ablative fractional carbon dioxide laser resurfacing with comparable efficacy to 0.02% triamcinolone acetonide cream in 20 subjects. ([Journal of Cosmetic Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30945430/))
- Topical treatment with 5% vitamin C and 0.1% madecassoside significantly improved clinical scores for wrinkles, suppleness, firmness, roughness, and skin hydration, along with functional and structural remodeling of the elastic fiber network in 20 female volunteers with photoaged skin after 6 months compared to baseline. ([Experimental Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/18503551/))
- Treatment with an asiaticoside-containing cream applied twice daily for 12 weeks significantly improved periorbital wrinkles in 65% of 27 female volunteers compared to a vehicle control cream. ([International Journal of Cosmetic Science, 2008](https://pubmed.ncbi.nlm.nih.gov/18452433/))
- Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33103316/))
- Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women. ([The Journal of Investigative Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/17882270/))
- Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging. ([Dermatologic Surgery, 2005](https://pubmed.ncbi.nlm.nih.gov/16029679/))
- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))

## What reviewers say

Based on a very large amount of data, this cream is highly praised for its barrier repair and anti-aging benefits, delivering a radiant glow and soothing sensitive skin. It is particularly effective for dry and mature skin types. However, individuals with oily or acne-prone skin may find it too heavy, potentially leading to congestion.

- Liked: Intense hydration glow (often mentioned)
- Liked: Soothing barrier repair (often mentioned)
- Disliked: Strong herbal scent (often mentioned)
- Liked: Anti-aging effects (sometimes noted)
- Liked: Rich absorbent texture (sometimes noted)
- Disliked: Greasy/sticky finish (sometimes noted)
- Disliked: Causes breakouts (rarely noted)
- Disliked: Packaging issues (rarely noted)

## How to apply

- Use your moisturizer twice a day in your AM and PM routines. Apply it daily to help keep breakouts under control.
- Apply after your cleanser and toner, and make sure to use your SPF right after in the morning.
- Gently spread a small amount of moisturizer over your face using soft motions. Let it absorb into the skin for a minute before getting dressed or applying makeup.
- Apply on slightly damp skin to help lock in extra moisture. This keeps your combination skin balanced without feeling heavy.
- Avoid the eye area and do a patch test before your first use. Stop using if you feel any irritation.
- Video: https://storage.pora.ai/2f72f5d69f07beeafc30237f829efbff.mp4

## Questions and answers

### What makes Centellian24 Madeca Cream a great fit for acne-prone skin?

Centellian24 Madeca Cream is a great fit for acne-prone skin because Centella Asiatica extract and niacinamide work together to calm irritation and help control excess oil. Madecassic acid further helps smooth texture and keep skin hydrated without clogging pores, while soothing ingredients like allantoin ensure a gentle and safe experience.
Sources: [Molecules, 2023](https://pubmed.ncbi.nlm.nih.gov/37446936/), [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/)

### Which ingredients make this cream a good fit for acne-prone skin?

Centella Asiatica and niacinamide make this cream a great fit for acne-prone skin because they help calm redness and keep oil under control. Ingredients like madecassic acid and allantoin also soothe your face and support a smooth, healthy skin barrier without harsh additives.
Sources: [Molecules, 2023](https://pubmed.ncbi.nlm.nih.gov/37446936/), [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/)

### What does Centella Asiatica do for acne-prone skin?

Centella asiatica helps calm acne-prone skin by reducing redness and soothing inflammation while supporting healing. It may also help manage breakouts by addressing factors like acne blemishes and irritation.
Sources: [Molecules, 2023](https://pubmed.ncbi.nlm.nih.gov/37446936/), [Journal of Alternative and Complementary Medicine, 2020](https://pubmed.ncbi.nlm.nih.gov/32310680/)

### What does Madecassoside do for acne-prone skin?

Madecassoside helps acne-prone skin by calming redness, reducing acne breakouts, and repairing the skin barrier to keep it healthy. It may also lower water loss and soothe irritation when used consistently in your routine.
Sources: [Molecules, 2023](https://pubmed.ncbi.nlm.nih.gov/37446936/), [Bioengineering, 2025](https://pubmed.ncbi.nlm.nih.gov/41007180/)

### Where does this cream go in a skincare routine for acne-prone skin?

This moisturizing treatment goes near the end of your evening routine, right after your treatment step. Using a daily moisturizer helps keep your skin balanced and is unlikely to clog pores.
Sources: [The Journal of Dermatological Treatment, 2022](https://pubmed.ncbi.nlm.nih.gov/32239984/), [International Journal of Cosmetic Science, 2020](https://pubmed.ncbi.nlm.nih.gov/31461548/)

### Can I use this cream with retinol, and in what order?

You can use this cream with retinol by applying the cream after your retinol to help soothe redness and keep your skin calm. Using a moisturizing treatment alongside retinol is unlikely to cause irritation and helps support your skin barrier while treating breakouts.
Sources: [Cutis, 2006](https://pubmed.ncbi.nlm.nih.gov/17121065/), [Journal of Drugs in Dermatology, 2023](https://pubmed.ncbi.nlm.nih.gov/37276158/)

### How often should I use this cream?

This moisturizing treatment is a great fit because Centella Asiatica and Niacinamide help soothe inflammation and balance oil for acne-prone skin. Daily application improves skin moisture and helps calm irritation.
Sources: [Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/32141711/), [Dermatology, 2003](https://pubmed.ncbi.nlm.nih.gov/14571069/)

### Can this cream clog pores, cause breakouts or purging for acne-prone skin?

This cream is unlikely to clog pores or cause breakouts for acne-prone skin, as it features soothing ingredients like Centella Asiatica and allantoin with a safe profile. Clinical studies show that Centella Asiatica and madecassoside help reduce inflammation and improve skin barrier function without causing irritation.
Sources: [Molecules, 2023](https://pubmed.ncbi.nlm.nih.gov/37446936/), [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/)

### Can I use this cream around the eyes or on my body?

Centellian24 Madeca Cream is a great fit because its Centella Asiatica and Niacinamide soothe irritation and calm acne-prone skin. It is safe to use on the body and around the eyes, where the skin is thinner, as it features gentle, hydrating ingredients with an excellent safety profile and no harsh substances.
Sources: [Surgical and Radiologic Anatomy, 2002](https://pubmed.ncbi.nlm.nih.gov/12375070/), [Molecules, 2023](https://pubmed.ncbi.nlm.nih.gov/37446936/)

### Is this cream fragrance-free and alcohol-free?

It has no drying alcohol and contains fragrance (limonene).

## Alternatives for acne-prone skin

- [Some By Mi Yuja Niacin Brightening Moisture Gel Cream](https://lovi.care/skincare/sa/p/some-by-mi/yuja-niacin-brightening-moisture-gel-cream/for/acne-prone-skin) — Superior fit — SAR 78.95 at Amazon
- [COSRX Advanced Snail 96 Mucin Power Essence](https://lovi.care/skincare/sa/p/cosrx/advanced-snail-96-mucin-power-essence/for/acne-prone-skin) — Superior fit — SAR 14.95 at Amazon
- [Drunk Elephant Protini Polypeptide Cream](https://lovi.care/skincare/sa/p/drunk-elephant/protini-polypeptide-cream/for/acne-prone-skin) — Superior fit — SAR 146.71 at Amazon

## Pairs well with

- Cleanser: [CeraVe Foaming Facial Cleanser](https://lovi.care/skincare/sa/p/cerave/foaming-facial-cleanser/for/acne-prone-skin) — Superior fit — SAR 36.33 at Amazon
- Hydrating Toner: [SOME BY MI Snail Truecica Miracle Repair Toner](https://lovi.care/skincare/sa/p/some-by-mi/snail-truecica-miracle-repair-toner/for/acne-prone-skin) — Superior fit — SAR 53.04 at Amazon
- SPF: [d'Alba Piedmont Waterfull Mild Sunscreen](https://lovi.care/skincare/sa/p/d-alba/piedmont-waterfull-mild-sunscreen/for/acne-prone-skin) — Superior fit — SAR 75.00 at Amazon

## Where to buy

- Amazon.sa: SAR 33.46 (https://www.amazon.sa/dp/B0D2XPMCJK?tag=lovisa02-21&linkCode=osi&th=1&psc=1)
Prices checked 4 Nov 2026.

## Ingredients

Centella Asiatica Extract, Cyclohexasiloxane, Niacinamide, Dicaprylyl Ether, 1,2-Hexanediol, C14-22 Alcohols, Dipropylene Glycol, Laminaria Japonica Extract, Eclipta Prostrata Leaf Extract, Ficus Carica Fruit Extract, Monarda Didyma Leaf Extract, Chrysanthemum Parthenium Extract Feverview Extract, Salvia Officinalis Leaf Water, Water-Soluble Collagen, Citrus Aurantium Dulcis Peel Oil, Hydrogenated Lecithin, Olea Europaea Oil Fruit Olive Oil Fruit, Centella Asiatica Oil, Polyglyceryl-10 Laurate, Sodium Acrylate Sodium Acryloyldimethyl Taurate Copolymer, Water, Dimethicone Vinyl Dimethicone Crosspolymer, Polyisobutene, C12-20 Alkyl Glucoside, Glyceryl Stearate Se, Acrylates C10-30 Alkyl Acrylate Crosspolymer, Tromethamine, Beta-Glucan, Sorbitan Oleate, Caprylyl Capryl Glucoside, Adenosine, Fructooligosaccharides, Sodium Stearoyl Glutamate, Disodium Edta, Glycerin, Sodium Laurate, Allantoin, Hydrolyzed Hyaluronic Acid, Lauric Acid, Madecassic Acid, Asiaticoside, Glucose, Asiatic Acid, Ceramide Np, Soluble Proteoglycan, Elastin, Sodium Hyaluronate, Polysorbate 60, Ethylhexylglycerin, Limonene
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/centellian24/madeca-cream/for/acne-prone-skin
- United Kingdom: https://lovi.care/skincare/uk/p/centellian24/madeca-cream/for/acne-prone-skin
- Ireland: https://lovi.care/skincare/ie/p/centellian24/madeca-cream/for/acne-prone-skin
- Germany: https://lovi.care/skincare/de/p/centellian24/madeca-cream/for/acne-prone-skin
- France: https://lovi.care/skincare/fr/p/centellian24/madeca-cream/for/acne-prone-skin
- Italy: https://lovi.care/skincare/it/p/centellian24/madeca-cream/for/acne-prone-skin
- Netherlands: https://lovi.care/skincare/nl/p/centellian24/madeca-cream/for/acne-prone-skin
- Spain: https://lovi.care/skincare/es/p/centellian24/madeca-cream/for/acne-prone-skin
- Canada: https://lovi.care/skincare/ca/p/centellian24/madeca-cream/for/acne-prone-skin
- Australia: https://lovi.care/skincare/au/p/centellian24/madeca-cream/for/acne-prone-skin
- Singapore: https://lovi.care/skincare/sg/p/centellian24/madeca-cream/for/acne-prone-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/centellian24/madeca-cream/for/acne-prone-skin (this page)
- United Arab Emirates: https://lovi.care/skincare/ae/p/centellian24/madeca-cream/for/acne-prone-skin