# Biologique Recherche Crème Dermopurifiante for mature skin

**Lovi Fit: Average fit for mature skin.**
Normal Skin Fit: Average · Effectiveness: Average · Safety: Excellent.

Page: https://lovi.care/skincare/sa/p/biologique-recherche/creme-dermopurifiante/for/mature-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Saudi Arabia.

Brand: [Biologique Recherche](https://lovi.care/skincare/sa/brands/biologique-recherche)
Category: [Serums and treatments](https://lovi.care/skincare/sa/best/serums)

This fit is calculated for the concerns frequently associated with mature skin: fine lines, wrinkles, and loss of firmness. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for mature skin; other serums fit it better.

## Why this fit

- Offers moderate suitability for normal skin, as Glycerin and Niacinamide provide hydration and barrier support, but the formula lacks ingredients specifically targeting wrinkles and fine lines.
- The product's inclusion of Centella Asiatica Extract and Arnica Montana Flower Extract ensures a gentle experience for normal skin, minimizing irritation.
- The safety profile is excellent, with no harsh ingredients and the presence of soothing agents, making it safe for your skin.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/sa/p/biologique-recherche/creme-dermopurifiante/for/oily-skin): High
- [Dry skin](https://lovi.care/skincare/sa/p/biologique-recherche/creme-dermopurifiante/for/dry-skin): Low
- [Combination skin](https://lovi.care/skincare/sa/p/biologique-recherche/creme-dermopurifiante/for/combination-skin): Average
- [Sensitive skin](https://lovi.care/skincare/sa/p/biologique-recherche/creme-dermopurifiante/for/sensitive-skin): Average
- [Acne-prone skin](https://lovi.care/skincare/sa/p/biologique-recherche/creme-dermopurifiante/for/acne-prone-skin): Average
- [Skin with dark spots](https://lovi.care/skincare/sa/p/biologique-recherche/creme-dermopurifiante/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/sa/p/biologique-recherche/creme-dermopurifiante/for/mature-skin): Average (this page)
- [Dry sensitive skin](https://lovi.care/skincare/sa/p/biologique-recherche/creme-dermopurifiante/for/dry-sensitive-skin): Low
- [Oily acne-prone skin](https://lovi.care/skincare/sa/p/biologique-recherche/creme-dermopurifiante/for/oily-acne-prone-skin): Average

## Key ingredients

Niacinamide, Mimosa Tenuiflora Extract, Centella Asiatica Extract, Arnica Montana Extract, Salicylic Acid

## What the research says

- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Cosmetic formulations containing 5% Centella asiatica extract showed the best efficacy in improving skin moisture and decreasing transepidermal water loss, while also exhibiting antiinflammatory properties in 25 volunteers compared to baseline measurements. ([Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/))
- Co-delivery of paeonol and madecassoside via nanoemulsions improved transdermal delivery, promoted barrier repair proteins, inhibited inflammatory cytokine secretion in cellular and 3D models, and reduced transepidermal water loss and acne in human facial skin compared to free components. ([Molecules, 2023](https://pubmed.ncbi.nlm.nih.gov/37446936/))
- Gels containing 1% Arnica montana L. flower extract successfully enhanced the volume of the lips and face with a reduction of wrinkles in humans. ([International Journal of Cosmetic Science, 2023](https://pubmed.ncbi.nlm.nih.gov/35984685/))
- Twice daily application of a multitargeted dermocosmetic cream provided comparable efficacy to benzoyl peroxide 5% gel in reducing inflammatory, non-inflammatory, and total lesions in 150 Caucasian subjects with mild-to-moderate acne over 56 days, while demonstrating superior skin tolerability. ([Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/37941097/))
- Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33103316/))
- Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women. ([The Journal of Investigative Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/17882270/))
- Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging. ([Dermatologic Surgery, 2005](https://pubmed.ncbi.nlm.nih.gov/16029679/))
- Chitosan/Mimosa tenuiflora bio-composite films exhibited improved thermal stability, increased water-uptake ability, antibacterial properties against Escherichia Coli and Micrococcus, and were non-toxic in cytotoxicity assays. ([International Journal of Biological Macromolecules, 2016](https://pubmed.ncbi.nlm.nih.gov/27693339/))
- Arabinogalactan-enriched fractions isolated from Mimosa tenuiflora bark significantly stimulated mitochondrial activity and proliferation in human primary dermal fibroblasts while having minor influence on HaCaT keratinocytes. ([Journal of Ethnopharmacology, 2009](https://pubmed.ncbi.nlm.nih.gov/19505559/))
- Topical application of 0.05% w/w ECa 233 gel reduced erythema index by 0.03 U and improved early crusting and general wound appearance compared to placebo in thirty individuals undergoing facial laser resurfacing. ([Journal of Alternative and Complementary Medicine, 2020](https://pubmed.ncbi.nlm.nih.gov/32310680/))
- Moisturizer containing 5% panthenol, madecassoside, and copper-zinc-manganese decreased adverse reactions and downtime after ablative fractional carbon dioxide laser resurfacing with comparable efficacy to 0.02% triamcinolone acetonide cream in 20 subjects. ([Journal of Cosmetic Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30945430/))
- Topical treatment with 5% vitamin C and 0.1% madecassoside significantly improved clinical scores for wrinkles, suppleness, firmness, roughness, and skin hydration, along with functional and structural remodeling of the elastic fiber network in 20 female volunteers with photoaged skin after 6 months compared to baseline. ([Experimental Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/18503551/))
- Topical application of Arnica montana ointment reduced the inflammatory response and oxidative damage in mice exposed to UVB radiation compared to untreated UVB-exposed skin. ([Cutaneous and Ocular Toxicology, 2020](https://pubmed.ncbi.nlm.nih.gov/32183539/))
- The protocol combining microcurrent with topical Arnica montana reduces inflammation, increases myofibroblast proliferation, and decreases macrophage presence in rats with skin lesions compared to controls. ([International Journal of Experimental Pathology, 2023](https://pubmed.ncbi.nlm.nih.gov/36752313/))
- Cryotherapy with liquid nitrogen achieved a higher cure rate (39%) than salicylic acid (24%) and a wait-and-see approach (16%) for cutaneous warts at 13 weeks in primary care patients. ([CMAJ, 2010](https://pubmed.ncbi.nlm.nih.gov/20837684/))
- A moisturizer containing licochalcone A, 1,2-decanediol, L-carnitine, and salicylic acid significantly reduced noninflammatory, inflammatory, and total acne lesion counts compared to a vehicle control in Thai patients during a 12-week maintenance phase. ([BioMed Research International, 2020](https://pubmed.ncbi.nlm.nih.gov/33150170/))
- Treatment with 2% supramolecular salicylic acid hydrogel resulted in a regression and markedly improvement rate of 51.01% compared to 43.10% for Adapaline gel in patients with mild to moderate facial acne vulgaris, showing no significant difference in efficacy. ([Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38590107/))

## Why other serums fit mature skin better

- Topical application of retinol and retinoic acid both increased epidermal thickness and upregulated collagen genes and proteins in human skin, with retinol producing similar histological and molecular changes to retinoic acid alongside a significant reduction in facial wrinkles after 12 weeks. ([Journal of Cosmetic Dermatology, 2016](https://pubmed.ncbi.nlm.nih.gov/26578346/))
- A topical serum containing vitamin C, vitamin E, and raspberry leaf cell culture extract improved skin color, elasticity, radiance, smoothness, scaliness, and wrinkles compared to the untreated contralateral side in fifty female volunteers. ([Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31975502/))

## What reviewers say

Users with oily, acne-prone, and congested skin frequently report that this cream effectively regulates sebum and clears breakouts without causing dryness. The distinct, often-mentioned yeasty scent is a common drawback, but the majority of users find the balancing, purifying, and redness-reducing benefits outweigh this sensory aspect.

- Liked: Clears acne (mostly mentioned)
- Disliked: Unpleasant scent (mostly mentioned)
- Liked: Balances oil production (often mentioned)
- Disliked: High price (often mentioned)
- Liked: Hydrates without greasiness (sometimes noted)
- Liked: Refines texture (sometimes noted)
- Liked: Soothes redness (sometimes noted)
- Disliked: Initial reaction (rarely noted)
- Disliked: Reformulation concerns (rarely noted)
- Disliked: Texture issues (rarely noted)

## How to apply

- Use this serum in your PM routine. Start by applying it 3 times a week, and work up to daily use if your skin likes it.
- Apply this serum after your toner and before your moisturizer.
- Gently press 2-3 drops of the serum into your skin and let it absorb for a minute.
- You can apply the serum on dry skin for the best results against fine lines.
- Always do a patch test before your first use and avoid the sensitive eye area.
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### How well does Biologique Recherche Crème Dermopurifiante work for mature skin?

Biologique Recherche Crème Dermopurifiante works moderately well for mature skin, as glycerin and niacinamide help hydrate and support the skin barrier, though the formula lacks ingredients specifically targeting wrinkles and fine lines. Treatments that fit mature skin better need high concentrations of potent antioxidants, nourishing oils, peptides, and ingredients that effectively smooth wrinkles and fine lines while keeping the skin soft and firm.
Sources: [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/), [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Which ingredients make this cream a good fit for mature skin?

Glycerin and Niacinamide help provide hydration and barrier support for mature skin. To be a better fit for this skin type, a product of this type needs high-quality ingredients that effectively target wrinkles and fine lines, along with potent antioxidants.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/), [International Journal of Cosmetic Science, 2023](https://pubmed.ncbi.nlm.nih.gov/35984685/)

### What does Niacinamide do for mature skin?

Niacinamide helps mature skin by smoothing out fine lines and wrinkles, reducing dark spots, and improving overall skin elasticity. It is also very well tolerated and supports a strong skin barrier to keep skin looking healthy.
Sources: [Antioxidants, 2021](https://pubmed.ncbi.nlm.nih.gov/34439563/), [Journal of Cosmetic Dermatology, 2004](https://pubmed.ncbi.nlm.nih.gov/17147561/)

### What does Mimosa Tenuiflora Extract do for mature skin?

Mimosa Tenuiflora Extract helps support skin repair and can improve the look of damaged skin over time. Clinical studies show that this extract assists with cell activity and tissue recovery, which may benefit aging skin by encouraging a smoother and more resilient feel.
Sources: [Journal of Ethnopharmacology, 2009](https://pubmed.ncbi.nlm.nih.gov/19505559/), [Journal of Ethnopharmacology, 2007](https://pubmed.ncbi.nlm.nih.gov/17088036/)

### Where does this cream go in a skincare routine for mature skin?

This treatment goes in the evening routine after cleansing and before moisturizing, following the general rule to use treatments at night for simplicity and safety around sun exposure. Because this cream is an average fit for mature skin, a product of this type for this skin needs added ingredients that specifically target wrinkles and fine lines to truly smooth the skin.

### Can I use this cream with retinol, and in what order?

You can use this cream alongside retinol by applying your retinol first and following with this treatment once it absorbs. This product is safe and gentle on the skin, though mature skin works best with a formula that includes ingredients targeting wrinkles and fine lines.

### How often should I use this cream?

This treatment is used in the evening once a week to start, and people who tolerate it well and see good results can carefully use it more often. Mature skin also needs ingredients that specifically target wrinkles and fine lines to get the best fit from this type of product.

### Can this cream clog pores, cause breakouts or purging for mature skin?

This cream is unlikely to clog pores or cause breakouts for mature skin since it has a very safe formula with soothing plant extracts, but it may not provide enough support against wrinkles. A product for mature skin needs powerful ingredients like peptides, retinol, and deep moisturizers to smooth fine lines and keep the skin plump.
Sources: [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/), [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Is this cream fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol. Cetyl alcohol is a fatty alcohol, which soften the skin.

## Alternatives for mature skin

- [Paula's Choice RESIST Super Antioxidant Concentrate Serum](https://lovi.care/skincare/sa/p/paula-s-choice/resist-super-antioxidant-concentrate-serum/for/mature-skin) — Superior fit — SAR 461.00 at Amazon
- [SkinCeuticals C E Ferulic](https://lovi.care/skincare/sa/p/skinceuticals/c-e-ferulic/for/mature-skin) — Superior fit — SAR 865.37 at Amazon
- [Drunk Elephant A-Passioni Retinol Cream](https://lovi.care/skincare/sa/p/drunk-elephant/a-passioni-retinol-cream/for/mature-skin) — High fit — SAR 491.04 at Amazon

## Pairs well with

- Cleanser: [Fresh Soy Face Cleanser](https://lovi.care/skincare/sa/p/fresh/soy-face-cleanser/for/mature-skin) — Superior fit — SAR 191.00 at Amazon
- Hydrating Toner: [COSRX Propolis Synergy Toner](https://lovi.care/skincare/sa/p/cosrx/full-fit-propolis-synergy-toner/for/mature-skin) — Superior fit — SAR 30.00 at Amazon
- Moisturizer: [Obagi Hydrate Luxe Moisture-Rich Cream](https://lovi.care/skincare/sa/p/obagi/hydrate-luxe/for/mature-skin) — Superior fit — SAR 329.18 at Amazon

## Where to buy

No store in Saudi Arabia has a checked price for this product, so the page shows none.

## Ingredients

Water, Propylene Glycol, Glycerin, Dicaprylyl Carbonate, Butylene Glycol, Sucrose Polystearate, C10-18 Triglycerides, Cetyl Alcohol, 1,2-Hexanediol, Niacinamide, Polyamide-5, Arctium Lappa Root Extract, Betula Alba Bark Extract, Enantia Chlorantha Bark Extract Moambe Jaune Bark Extract, Equisetum Arvense Extract, Mimosa Tenuiflora Bark Extract Acacia Decurrens Bark Extract, Hedera Helix Stem Extract Leaf, Fucus Vesiculosus Extract, Centella Asiatica Extract, Spiraea Ulmaria Extract, Arnica Montana Flower Extract, Rosa Canina Fruit Extract, Achillea Millefolium Extract Common Yarrow Extract, Aesculus Hippocastanum Seed Extract, Lavandula Angustifolia Flower Extract Lavender Flower Extract, Thymus Vulgaris Extract, Myrtus Communis Extract, Onion Bulb Extract, Commiphora Myrrha Extract Resin, Oleanolic Acid, Glycine Soja Oil Soybean Oil, Yeast Extract, Citric Acid, Tocopherol, Sodium Stearoyl Glutamate, Hydrogenated Polyisobutene, Polyacrylate Crosspolymer-6, Caprylyl Glycol, Phenoxyethanol, Sodium Benzoate, Potassium Sorbate, Sorbic Acid
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/biologique-recherche/creme-dermopurifiante/for/mature-skin
- United Kingdom: https://lovi.care/skincare/uk/p/biologique-recherche/creme-dermopurifiante/for/mature-skin
- Ireland: https://lovi.care/skincare/ie/p/biologique-recherche/creme-dermopurifiante/for/mature-skin
- Germany: https://lovi.care/skincare/de/p/biologique-recherche/creme-dermopurifiante/for/mature-skin
- France: https://lovi.care/skincare/fr/p/biologique-recherche/creme-dermopurifiante/for/mature-skin
- Italy: https://lovi.care/skincare/it/p/biologique-recherche/creme-dermopurifiante/for/mature-skin
- Netherlands: https://lovi.care/skincare/nl/p/biologique-recherche/creme-dermopurifiante/for/mature-skin
- Spain: https://lovi.care/skincare/es/p/biologique-recherche/creme-dermopurifiante/for/mature-skin
- Canada: https://lovi.care/skincare/ca/p/biologique-recherche/creme-dermopurifiante/for/mature-skin
- Australia: https://lovi.care/skincare/au/p/biologique-recherche/creme-dermopurifiante/for/mature-skin
- Singapore: https://lovi.care/skincare/sg/p/biologique-recherche/creme-dermopurifiante/for/mature-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/biologique-recherche/creme-dermopurifiante/for/mature-skin (this page)
- United Arab Emirates: https://lovi.care/skincare/ae/p/biologique-recherche/creme-dermopurifiante/for/mature-skin