# BIOEFFECT EGF Power Serum for sensitive skin

**Lovi Fit: High fit for sensitive skin.**
Normal Skin Fit: High · Effectiveness: Average · Safety: High.

Page: https://lovi.care/skincare/sa/p/bioeffect/egf-power-serum/for/sensitive-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Saudi Arabia.

Brand: [BIOEFFECT](https://lovi.care/skincare/sa/brands/bioeffect)
Category: [Serums and treatments](https://lovi.care/skincare/sa/best/serums)

This fit is calculated for the concerns frequently associated with sensitive skin: redness, stinging, and reactions to new products. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

A great choice for sensitive skin; a few serums fit it even better.

## Why this fit

- Highly suitable for normal skin due to the humectant action of Sodium Hyaluronate and Glycerin, complemented by Rh-Oligopeptide-1 Barley Sh-Oligopeptide-1 and Kgf Barley Sh-Polypeptide-3 for collagen stimulation.
- While the serum offers excellent skin regeneration for anti-aging effects, it lacks targeted ingredients to address your specific concerns of redness and irritation.
- The product is safe for your sensitive skin, as it contains no harsh or prohibited ingredients that could cause irritation.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/sa/p/bioeffect/egf-power-serum/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/sa/p/bioeffect/egf-power-serum/for/dry-skin): High
- [Combination skin](https://lovi.care/skincare/sa/p/bioeffect/egf-power-serum/for/combination-skin): Average
- [Sensitive skin](https://lovi.care/skincare/sa/p/bioeffect/egf-power-serum/for/sensitive-skin): High (this page)
- [Acne-prone skin](https://lovi.care/skincare/sa/p/bioeffect/egf-power-serum/for/acne-prone-skin): Average
- [Skin with dark spots](https://lovi.care/skincare/sa/p/bioeffect/egf-power-serum/for/dark-spots): High
- [Mature skin](https://lovi.care/skincare/sa/p/bioeffect/egf-power-serum/for/mature-skin): High
- [Dry sensitive skin](https://lovi.care/skincare/sa/p/bioeffect/egf-power-serum/for/dry-sensitive-skin): High
- [Oily acne-prone skin](https://lovi.care/skincare/sa/p/bioeffect/egf-power-serum/for/oily-acne-prone-skin): Average

## Key ingredients

Rh-Oligopeptide-1, Sodium Hyaluronate, Acetyl Glucosamine, Hordeum Vulgare Seed Extract, Glycerin

## What the research says

- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Topical hyaluronic acid filler serum combined with Botulinum toxin type A lengthened the duration of the toxin's effect in reducing wrinkles compared to Botulinum toxin type A alone. ([Dermatologic Therapy, 2022](https://pubmed.ncbi.nlm.nih.gov/36200921/))
- Optimized transfersomes loaded with epigallocatechin-3-gallate and hyaluronic acid increased cell viability while reducing lipid peroxidation, intracellular ROS, and MMP expression in HaCaT cells, and exhibited higher skin permeation and deposition compared to plain EGCG. ([Drug Delivery, 2017](https://pubmed.ncbi.nlm.nih.gov/28155509/))
- Topical cosmetic products containing hyaluronic acid, N-acetyl glucosamine, and gamma-amino butyric acid improved skin hydration by 24.28% to 33.60%, elasticity by 11.98%, and skin lightening by 5.26% over 2 months in 20 female participants. ([Journal of Cosmetic and Laser Therapy, 2019](https://pubmed.ncbi.nlm.nih.gov/30040516/))
- Topical epidermal growth factor combined with silver sulfadiazine accelerated the rate of epidermal regeneration and significantly decreased healing time by approximately 1 to 1.5 days across all stages of healing in skin-graft-donor sites of 12 patients compared to silver sulfadiazine alone. ([The New England Journal of Medicine, 1989](https://pubmed.ncbi.nlm.nih.gov/2659995/))
- Topical recombinant human epidermal growth factor combined with ablative fractional carbon dioxide laser significantly improved striae surface texture and showed significantly greater participant satisfaction regarding marked improvement compared to ablative fractional carbon dioxide laser combined with Aloe vera gel in patients with striae alba. ([Lasers in Surgery and Medicine, 2020](https://pubmed.ncbi.nlm.nih.gov/30614013/))
- Topical EGF combined with fractional CO2 laser significantly improves the clinical appearance of atrophic acne scars and decreases skin pigmentation compared to fractional CO2 laser alone in patients with atrophic acne scars. ([The Journal of Clinical and Aesthetic Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/35942017/))
- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))
- Topical 2% N-acetyl glucosamine reduced facial hyperpigmentation in an 8-week split-face clinical test, with an even greater effect observed when combined with 4% niacinamide. ([Journal of Cosmetic Dermatology, 2007](https://pubmed.ncbi.nlm.nih.gov/17348991/))
- N-acetyl-glucosamine-loaded nanostructured lipid carriers successfully delivered the hydrophilic agent through the skin and reduced melanin distribution in healthy volunteers. ([Advanced Pharmaceutical Bulletin, 2016](https://pubmed.ncbi.nlm.nih.gov/28101465/))
- Liposomes containing N-acetyl glucosamine prepared using the fusion method significantly increased skin moisture content compared to empty liposomes in human volunteers over a 5-hour period. ([Journal of Cosmetic Dermatology, 2013](https://pubmed.ncbi.nlm.nih.gov/23725302/))
- The emollient V0034CR significantly reduced TEWL compared to vehicle and vehicle plus glycerol, and significantly increased corneometry scores compared to vehicle and vehicle plus petrolatum in healthy volunteers with dry skin, demonstrating combined barrier function improvement from petrolatum and hydration improvement from glycerol. ([Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31532576/))
- Ten days of treatment with a cream containing 20% glycerin significantly increased skin hydration measured by corneometer values in 17 healthy volunteers compared to a placebo cream, but showed no influence on transepidermal water loss or skin sensitivity to an irritating surfactant. ([International Journal of Cosmetic Science, 2001](https://pubmed.ncbi.nlm.nih.gov/18498456/))
- Niacinamide/glycerin body moisturizers provided better rapid and prolonged improvement of cosmetic xerosis through functional improvement of stratum corneum barrier function compared to no treatment and conventional moisturizers in female subjects. ([Journal of Drugs in Dermatology, 2012](https://pubmed.ncbi.nlm.nih.gov/22206073/))

## What reviewers say

This serum is highly effective for mature, dry, and aging skin, with users frequently reporting improvements in texture, firmness, and radiance. Based on limited data, the product is praised for visibly reducing fine lines and hyperpigmentation, leaving the complexion plumper and more even-toned. Some users note a tacky feel after application and that results require patience, while the high price point is a common concern.

- Liked: Improves skin texture (mostly mentioned)
- Disliked: High price point (mostly mentioned)
- Liked: Boosts skin radiance (often mentioned)
- Liked: Reduces fine lines (often mentioned)
- Liked: Deeply hydrating (sometimes noted)
- Liked: Gentle formula (sometimes noted)
- Disliked: Requires patience (sometimes noted)
- Disliked: Tacky skin feel (sometimes noted)
- Disliked: Limited care feeling (rarely noted)

## How to apply

- Use your serum in the PM routine, starting 3 times a week before building up to daily use if your skin is happy.
- Apply the serum after cleansing and toning, but before putting on your moisturizer for the best results.
- Gently press 2-3 drops of the serum into your skin and wait a minute ⏱ for it to soak in.
- Since your skin is sensitive and easily irritated, apply the serum on completely dry skin to help keep it calm.
- Always do a patch test before your first use and avoid getting the serum too close to your eyes .
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### What makes BIOEFFECT EGF Power Serum a great fit for sensitive skin?

BIOEFFECT EGF Power Serum is a great fit for sensitive skin because it is very safe and contains no harsh or prohibited ingredients that could cause irritation. It also deeply hydrates the skin with sodium hyaluronate and glycerin, while plant-based growth factors help stimulate collagen for smooth and healthy-looking skin.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Which ingredients make this serum a good fit for sensitive skin?

Sodium hyaluronate and glycerin make this serum a good fit for sensitive skin by boosting hydration, while plant-based growth factors help stimulate collagen. The formula is safe for sensitive skin because it lacks harsh ingredients that could cause irritation.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### What does EGF do for sensitive skin?

EGF helps calm sensitive skin by supporting barrier recovery and reducing moisture loss after irritation. It also helps protect skin cells from environmental damage and lowers inflammation to keep your face feeling soft and smooth.
Sources: [Skin Pharmacology and Physiology, 2013](https://pubmed.ncbi.nlm.nih.gov/23108135/)

### What does Hyaluronic Acid do for sensitive skin?

Hyaluronic acid helps calm and hydrate sensitive skin while supporting the skin barrier to keep it soft and comfortable. Clinical studies show it improves surface moisture and reduces dryness, roughness, and redness without irritation.
Sources: [Journal of Drugs in Dermatology, 2025](https://pubmed.ncbi.nlm.nih.gov/41037531/), [Journal of Cosmetic Dermatology, 2018](https://pubmed.ncbi.nlm.nih.gov/29356277/)

### Where does this serum go in a skincare routine for sensitive skin?

This serum goes in your evening routine, applied after your toner and before your moisturizer. Putting it on at night helps keep your routine simple and adds extra safety around sun exposure.

### Can I use this serum with retinol, and in what order?

You can use this serum in your evening routine after your toner and before your moisturizer. When combining it with retinol, apply your retinol first, let it absorb, and then follow with this treatment to keep your skin feeling soft and calm.
Sources: [Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38102855/)

### How often should I use this serum?

Apply this serum in your evening routine, using it as part of your nighttime steps. The product is safe for sensitive skin as it contains no harsh or prohibited ingredients that could cause irritation.

### Can this serum clog pores, cause breakouts or purging for sensitive skin?

This serum is unlikely to clog pores or cause breakouts on sensitive skin because it contains no harsh ingredients that typically trigger irritation or congestion. It helps keep your skin feeling soft and smooth without heavy oils that can block pores.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Is this serum fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for sensitive skin

- [Paula's Choice RESIST Super Antioxidant Concentrate Serum](https://lovi.care/skincare/sa/p/paula-s-choice/resist-super-antioxidant-concentrate-serum/for/sensitive-skin) — Superior fit — SAR 461.00 at Amazon
- [SkinCeuticals C E Ferulic](https://lovi.care/skincare/sa/p/skinceuticals/c-e-ferulic/for/sensitive-skin) — High fit — SAR 865.37 at Amazon
- [Neogen Dermalogy Real Vitamin C Serum](https://lovi.care/skincare/sa/p/neogen-dermalogy/real-vitamin-c-serum/for/sensitive-skin) — High fit — SAR 130.97 at Amazon

## Pairs well with

- Cleanser: [Fresh Soy Face Cleanser](https://lovi.care/skincare/sa/p/fresh/soy-face-cleanser/for/sensitive-skin) — Superior fit — SAR 191.00 at Amazon
- Soothing Toner: [Clarins Toning Lotion with Camomile](https://lovi.care/skincare/sa/p/clarins/soothing-toning-lotion/for/sensitive-skin) — Superior fit — SAR 141.00 at Amazon
- Moisturizer with Sun Protection: [Bioderma Bioderma Photoderm Mineral SPF 50+](https://lovi.care/skincare/sa/p/bioderma/photoderm-mineral-fluide-spf50/for/sensitive-skin) — Superior fit — SAR 132.22 at Amazon

## Where to buy

No store in Saudi Arabia has a checked price for this product, so the page shows none.

## Ingredients

Glycerin, Water, Sodium Citrate, Acetyl Glucosamine Nag, Isopentyldiol, Phenoxyethanol, Sodium Chloride, Sodium Hyaluronate, Citric Acid, Hordeum Vulgare Seed Extract, Rh-Oligopeptide-1 Barley Sh-Oligopeptide-1, Kgf Barley Sh-Polypeptide-3
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/bioeffect/egf-power-serum/for/sensitive-skin
- United Kingdom: https://lovi.care/skincare/uk/p/bioeffect/egf-power-serum/for/sensitive-skin
- Ireland: https://lovi.care/skincare/ie/p/bioeffect/egf-power-serum/for/sensitive-skin
- Germany: https://lovi.care/skincare/de/p/bioeffect/egf-power-serum/for/sensitive-skin
- France: https://lovi.care/skincare/fr/p/bioeffect/egf-power-serum/for/sensitive-skin
- Italy: https://lovi.care/skincare/it/p/bioeffect/egf-power-serum/for/sensitive-skin
- Netherlands: https://lovi.care/skincare/nl/p/bioeffect/egf-power-serum/for/sensitive-skin
- Spain: https://lovi.care/skincare/es/p/bioeffect/egf-power-serum/for/sensitive-skin
- Canada: https://lovi.care/skincare/ca/p/bioeffect/egf-power-serum/for/sensitive-skin
- Australia: https://lovi.care/skincare/au/p/bioeffect/egf-power-serum/for/sensitive-skin
- Singapore: https://lovi.care/skincare/sg/p/bioeffect/egf-power-serum/for/sensitive-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/bioeffect/egf-power-serum/for/sensitive-skin (this page)
- United Arab Emirates: https://lovi.care/skincare/ae/p/bioeffect/egf-power-serum/for/sensitive-skin