# Anua Heartleaf 80 Moisture Soothing Ampoule for dry sensitive skin

**Lovi Fit: Superior fit for dry sensitive skin.**
Dry Skin Fit: Superior · Effectiveness: Superior · Safety: Excellent.

Page: https://lovi.care/skincare/sa/p/anua/heartleaf-80-moisture-soothing-ampoule/for/dry-sensitive-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Saudi Arabia.

Brand: [Anua](https://lovi.care/skincare/sa/brands/anua)
Category: [Moisturizers and moisturizing serums](https://lovi.care/skincare/sa/best/moisturizers)

This fit is calculated for the concerns frequently associated with dry sensitive skin: flakiness, tightness, redness, fine lines, and wrinkles. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

One of the best moisturizers for dry sensitive skin.

## Why this fit

- Excellent suitability for your dry and sensitive skin as Houttuynia Cordata Extract and Hyaluronic Acid provide superior hydration and soothing effects, addressing dryness and flakiness.
- The inclusion of Panthenol and Allantoin further supports barrier repair and calms irritation, enhancing overall skin comfort.
- This formula is safe for your skin, containing no harsh ingredients and featuring a blend of calming agents.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/sa/p/anua/heartleaf-80-moisture-soothing-ampoule/for/oily-skin): High
- [Dry skin](https://lovi.care/skincare/sa/p/anua/heartleaf-80-moisture-soothing-ampoule/for/dry-skin): Superior
- [Combination skin](https://lovi.care/skincare/sa/p/anua/heartleaf-80-moisture-soothing-ampoule/for/combination-skin): High
- [Sensitive skin](https://lovi.care/skincare/sa/p/anua/heartleaf-80-moisture-soothing-ampoule/for/sensitive-skin): High
- [Acne-prone skin](https://lovi.care/skincare/sa/p/anua/heartleaf-80-moisture-soothing-ampoule/for/acne-prone-skin): Superior
- [Skin with dark spots](https://lovi.care/skincare/sa/p/anua/heartleaf-80-moisture-soothing-ampoule/for/dark-spots): High
- [Mature skin](https://lovi.care/skincare/sa/p/anua/heartleaf-80-moisture-soothing-ampoule/for/mature-skin): High
- [Dry sensitive skin](https://lovi.care/skincare/sa/p/anua/heartleaf-80-moisture-soothing-ampoule/for/dry-sensitive-skin): Superior (this page)
- [Oily acne-prone skin](https://lovi.care/skincare/sa/p/anua/heartleaf-80-moisture-soothing-ampoule/for/oily-acne-prone-skin): Superior

## Key ingredients

Heartleaf Extract, Hyaluronic Acid, Glycerin, Allantoin, Panthenol

## What the research says

- Topical hyaluronic acid filler serum combined with Botulinum toxin type A lengthened the duration of the toxin's effect in reducing wrinkles compared to Botulinum toxin type A alone. ([Dermatologic Therapy, 2022](https://pubmed.ncbi.nlm.nih.gov/36200921/))
- Topical dexpanthenol acts as a moisturizer, improves stratum corneum hydration, accelerates wound healing and epidermal regeneration, reduces erythema, and improves symptoms of skin irritation compared to vehicle or no pretreatment. ([American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/))
- A new topical panthenol-containing emollient significantly improved transepidermal water loss reduction, stratum corneum hydration, and intercellular lipid lamellae length compared with control in healthy subjects without negatively impacting bacterial viability. ([The Journal of Dermatological Treatment, 2017](https://pubmed.ncbi.nlm.nih.gov/27425824/))
- A panthenol-enriched mask significantly decreased erythema and hyperpigmentation, increased sebum and stratum corneum moisture, and reduced transepidermal water loss compared to a saline dressing in 60 subjects undergoing facial laser treatment. ([Journal of Cosmetic Dermatology, 2025](https://pubmed.ncbi.nlm.nih.gov/40613435/))
- Quercetin phospholipids 1% cream significantly reduced UV-, histamine-, and chemical-induced skin erythema (-10.05%) and mean wheal diameter in 30 healthy human volunteers, showing comparable efficacy to 1% dexchlorpheniramine cream. ([Clinical, Cosmetic and Investigational Dermatology, 2016](https://pubmed.ncbi.nlm.nih.gov/27013898/))
- Quercetin-loaded niosomes formulated with Span60-RH40 at a 9:11 mass ratio improved quercetin solubility, photostability, sustained release, and transdermal penetration, yielding a skin retention 2.95 times higher than quercetin solution. ([Molecules, 2019](https://pubmed.ncbi.nlm.nih.gov/31238562/))
- Optimized rutin-loaded glycerosomes formulated into a nanosunscreen gel demonstrated sustained drug release, greater skin permeation, good antioxidant activity, and better epidermal retention compared to the dermis, indicating high safety, stability, and sun protection factor values for topical administration. ([Gels, 2023](https://pubmed.ncbi.nlm.nih.gov/37754433/))
- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))
- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- The emollient V0034CR significantly reduced TEWL compared to vehicle and vehicle plus glycerol, and significantly increased corneometry scores compared to vehicle and vehicle plus petrolatum in healthy volunteers with dry skin, demonstrating combined barrier function improvement from petrolatum and hydration improvement from glycerol. ([Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31532576/))
- Ten days of treatment with a cream containing 20% glycerin significantly increased skin hydration measured by corneometer values in 17 healthy volunteers compared to a placebo cream, but showed no influence on transepidermal water loss or skin sensitivity to an irritating surfactant. ([International Journal of Cosmetic Science, 2001](https://pubmed.ncbi.nlm.nih.gov/18498456/))
- Topical gel containing chitosan, 0.2% chlorhexidine, allantoin and dexpanthenol did not improve postoperative comfort regarding swelling and pain, but improved the wound's aesthetic appearance following impacted lower third molar extraction compared to no gel. ([Medicina Oral, Patologia Oral Y Cirugia Bucal, 2016](https://pubmed.ncbi.nlm.nih.gov/27475700/))
- A topical gel containing chitosan, chlorhexidine, allantoin, and dexpanthenol significantly reduced postoperative pain, trismus, swelling, and analgesic consumption, while improving wound healing after third molar surgery compared to a placebo. ([Medicina Oral, Patologia Oral Y Cirugia Bucal, 2020](https://pubmed.ncbi.nlm.nih.gov/32683390/))
- An overnight patch containing Allium cepa extract and allantoin safely promotes scar healing after dermatologic surgery, resulting in significantly greater reductions in observer- and patient-assessed POSAS scores compared to no treatment. ([Aesthetic Plastic Surgery, 2018](https://pubmed.ncbi.nlm.nih.gov/29948103/))
- Moisturizer containing 5% panthenol, madecassoside, and copper-zinc-manganese decreased adverse reactions and downtime after ablative fractional carbon dioxide laser resurfacing with comparable efficacy to 0.02% triamcinolone acetonide cream in 20 subjects. ([Journal of Cosmetic Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30945430/))
- Topical dexpanthenol formulated in lipophilic vehicles improved stratum corneum hydration and reduced transepidermal water loss compared to vehicle control in humans. ([Arzneimittel-Forschung, 2000](https://pubmed.ncbi.nlm.nih.gov/10965426/))
- Hyaluronic acid, hyaluronic acid plus dexpanthenol, and isotonic saline nasal sprays all significantly improved dry nose symptoms over four weeks in 240 patients, with hyaluronic acid plus dexpanthenol providing superior nasal moisturisation compared to the other two. ([Auris, Nasus, Larynx, 2020](https://pubmed.ncbi.nlm.nih.gov/32067777/))

## What reviewers say

Based on a very large amount of data, this ampoule is widely praised by users with sensitive and acne-prone skin for its ability to rapidly soothe redness and provide deep hydration without clogging pores. While most users achieve a "glass skin" glow and reduced inflammation, a minority experience a tacky finish or find it ineffective for severe breakouts.

- Liked: Soothing redness (mostly mentioned)
- Liked: Deep hydration (often mentioned)
- Liked: Acne care (sometimes noted)
- Liked: Lightweight texture (sometimes noted)
- Disliked: Small quantity (sometimes noted)
- Disliked: Sticky finish (sometimes noted)
- Disliked: Caused breakouts (rarely noted)
- Disliked: Lack of results (rarely noted)

## How to apply

- Could be used as part of your AM or PM routine. Start using this moisturizer 3 times a week and move to daily use if your dry skin tolerates it well.
- Apply this moisturizer after cleansing and toner in the morning, or after your serum in the evening. Always pair it with SPF in the morning.
- Gently press a small amount of the moisturizer into your skin. Avoid rubbing it harshly to protect your sensitive skin.
- Apply the moisturizer on slightly damp skin to help with hydration absorption. This also works well for dry and flaky skin types.
- Do a patch test before your first use. Avoid the eye area to prevent any irritation.
- Video: https://storage.pora.ai/2f72f5d69f07beeafc30237f829efbff.mp4

## Questions and answers

### What makes Anua Heartleaf 80 Ampoule one of the best fits for dry sensitive skin?

This ampoule is a great fit for your dry sensitive skin because heartleaf extract and hyaluronic acid give you deep moisture and comfort while calming any flakiness. Panthenol and allantoin also help repair your skin barrier and soothe irritation.
Sources: [American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/), [The Journal of Dermatological Treatment, 2017](https://pubmed.ncbi.nlm.nih.gov/27425824/)

### Which ingredients make this serum a good fit for dry sensitive skin?

Heartleaf extract and hyaluronic acid make this serum a great fit by providing deep moisture to help with dryness and flakiness, while panthenol and allantoin calm irritation and help repair your skin barrier. These soothing ingredients work gently together to keep sensitive skin comfortable and smooth without any harsh additives.
Sources: [American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/), [The Journal of Dermatological Treatment, 2017](https://pubmed.ncbi.nlm.nih.gov/27425824/)

### What does Heartleaf Extract do for dry sensitive skin?

Heartleaf Extract helps calm dry sensitive skin by reducing irritation and supporting the skin barrier. It is unlikely to cause trouble and may help keep your skin feeling soft and smooth.
Sources: [International Journal of Biological Macromolecules, 2025](https://pubmed.ncbi.nlm.nih.gov/40393586/)

### What does Hyaluronic Acid do for dry sensitive skin?

Hyaluronic acid is a great fit for dry, sensitive skin because it brings a large boost in hydration, making the skin feel soft and smooth while improving barrier function. It helps calm tightness and dryness, and is unlikely to cause irritation.
Sources: [Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/), [Dermatology and Therapy, 2021](https://pubmed.ncbi.nlm.nih.gov/34176098/)

### Where does this serum go in a skincare routine for dry sensitive skin?

This treatment goes in your evening routine after your toner and before your moisturizer. Using it at night is simple and keeps your skin safe around sun exposure, while ingredients like panthenol help calm irritation and repair your skin barrier.
Sources: [American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/), [The Journal of Dermatological Treatment, 2017](https://pubmed.ncbi.nlm.nih.gov/27425824/)

### Can I use this serum with retinol, and in what order?

You can use this serum with retinol by applying it before your retinol to help calm your skin and lower the likelihood of irritation. Using a barrier-supporting moisturizer alongside active treatments is well-supported by studies showing improved comfort and skin recovery.
Sources: [Cutis, 2006](https://pubmed.ncbi.nlm.nih.gov/17121065/), [American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/)

### How often should I use this serum?

You can use this treatment in your evening routine daily, and some people may also use it in the morning or twice a day. Regular application helps keep dry and sensitive skin calm, soft, and well hydrated.
Sources: [Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/32141711/), [Health Science Reports, 2021](https://pubmed.ncbi.nlm.nih.gov/34141902/)

### Can this serum clog pores, cause breakouts or purging for dry sensitive skin?

This serum is unlikely to clog pores or cause breakouts for dry sensitive skin, as it features a gentle formula without harsh ingredients. Reviewers only rarely report breakouts from using it.

### Can I use this serum around the eyes or on my body?

This moisturizing treatment is gentle enough for the thin skin around the eyes and dry areas on the body because it contains soothing ingredients like Panthenol and Hyaluronic Acid that hydrate and calm irritation. Regular application helps improve skin comfort and barrier repair without causing irritation.
Sources: [Surgical and Radiologic Anatomy, 2002](https://pubmed.ncbi.nlm.nih.gov/12375070/), [Polymers, 2023](https://pubmed.ncbi.nlm.nih.gov/37896378/)

### Is this serum fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for dry sensitive skin

- [COSRX Hydrium Triple Hyaluronic Moisture Ampoule](https://lovi.care/skincare/sa/p/cosrx/hydrium-triple-hyaluronic-moisture-ampoule/for/dry-sensitive-skin) — Superior fit — SAR 162.01 at Amazon
- [Torriden DIVE-IN Low Molecular Hyaluronic Acid Serum](https://lovi.care/skincare/sa/p/torriden/dive-in-low-molecular-hyaluronic-acid-serum/for/dry-sensitive-skin) — High fit — SAR 69.70 at Amazon
- [Kiehl's Midnight Recovery Concentrate](https://lovi.care/skincare/sa/p/kiehl-s/midnight-recovery-concentrate/for/dry-sensitive-skin) — High fit — SAR 786.00 at Amazon

## Pairs well with

- Cleanser: [Illiyoon Ceramide Derma Amino Cleansing Foam](https://lovi.care/skincare/sa/p/illiyoon/ceramide-derma-amino-cleansing-foam/for/dry-sensitive-skin) — Superior fit — SAR 149.44 at Amazon
- Soothing Toner: [Clarins Toning Lotion with Camomile](https://lovi.care/skincare/sa/p/clarins/soothing-toning-lotion/for/dry-sensitive-skin) — Superior fit — SAR 141.00 at Amazon
- Moisturizer with Sun Protection: [d'Alba UVessence Mild Waterfull Sun Cream SPF 50](https://lovi.care/skincare/sa/p/d-alba/uvessence-mild-waterfull-sun-cream-spf-50/for/dry-sensitive-skin) — Superior fit — SAR 89.00 at Amazon

## Where to buy

- Amazon.sa: SAR 17.10 (https://www.amazon.sa/dp/B08CMVXQ9W?tag=lovisa02-21&linkCode=osi&th=1&psc=1)
Prices checked 5 Nov 2026.

## Ingredients

Water, Houttuynia Cordata Extract, Glycerin, Butylene Glycol, 1,2-Hexanediol, Hyaluronic Acid, Betaine, Allantoin, Panthenol, Ethylhexylglycerin, Disodium Edta
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/anua/heartleaf-80-moisture-soothing-ampoule/for/dry-sensitive-skin
- United Kingdom: https://lovi.care/skincare/uk/p/anua/heartleaf-80-moisture-soothing-ampoule/for/dry-sensitive-skin
- Ireland: https://lovi.care/skincare/ie/p/anua/heartleaf-80-moisture-soothing-ampoule/for/dry-sensitive-skin
- Germany: https://lovi.care/skincare/de/p/anua/heartleaf-80-moisture-soothing-ampoule/for/dry-sensitive-skin
- France: https://lovi.care/skincare/fr/p/anua/heartleaf-80-moisture-soothing-ampoule/for/dry-sensitive-skin
- Italy: https://lovi.care/skincare/it/p/anua/heartleaf-80-moisture-soothing-ampoule/for/dry-sensitive-skin
- Netherlands: https://lovi.care/skincare/nl/p/anua/heartleaf-80-moisture-soothing-ampoule/for/dry-sensitive-skin
- Spain: https://lovi.care/skincare/es/p/anua/heartleaf-80-moisture-soothing-ampoule/for/dry-sensitive-skin
- Canada: https://lovi.care/skincare/ca/p/anua/heartleaf-80-moisture-soothing-ampoule/for/dry-sensitive-skin
- Australia: https://lovi.care/skincare/au/p/anua/heartleaf-80-moisture-soothing-ampoule/for/dry-sensitive-skin
- Singapore: https://lovi.care/skincare/sg/p/anua/heartleaf-80-moisture-soothing-ampoule/for/dry-sensitive-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/anua/heartleaf-80-moisture-soothing-ampoule/for/dry-sensitive-skin (this page)
- United Arab Emirates: https://lovi.care/skincare/ae/p/anua/heartleaf-80-moisture-soothing-ampoule/for/dry-sensitive-skin