# Aestura A-Cica 365 Blemish Calming Serum for dry skin

**Lovi Fit: Average fit for dry skin.**
Dry Skin Fit: High · Effectiveness: Average · Safety: Excellent.

Page: https://lovi.care/skincare/sa/p/aestura/a-cica-365-blemish-calming-serum/for/dry-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Saudi Arabia.

Brand: [Aestura](https://lovi.care/skincare/sa/brands/aestura)
Category: [Serums and treatments](https://lovi.care/skincare/sa/best/serums)

This fit is calculated for the concerns frequently associated with dry skin: flakiness, tightness, dehydration, fine lines, and wrinkles. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for dry skin; other serums fit it better.

## Why this fit

- Offers moderate hydration for your dry skin, as glycerin and squalane provide humectant and emollient actions respectively, helping to alleviate flakiness.
- The inclusion of madecassoside and beta-glucan offers excellent calming and soothing benefits, addressing general irritation without exacerbating dryness.
- The formula is safe for your dry skin, with no risks of irritation due to the absence of harsh ingredients and the presence of soothing components.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/sa/p/aestura/a-cica-365-blemish-calming-serum/for/oily-skin): High
- [Dry skin](https://lovi.care/skincare/sa/p/aestura/a-cica-365-blemish-calming-serum/for/dry-skin): Average (this page)
- [Combination skin](https://lovi.care/skincare/sa/p/aestura/a-cica-365-blemish-calming-serum/for/combination-skin): High
- [Sensitive skin](https://lovi.care/skincare/sa/p/aestura/a-cica-365-blemish-calming-serum/for/sensitive-skin): High
- [Acne-prone skin](https://lovi.care/skincare/sa/p/aestura/a-cica-365-blemish-calming-serum/for/acne-prone-skin): High
- [Skin with dark spots](https://lovi.care/skincare/sa/p/aestura/a-cica-365-blemish-calming-serum/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/sa/p/aestura/a-cica-365-blemish-calming-serum/for/mature-skin): High
- [Dry sensitive skin](https://lovi.care/skincare/sa/p/aestura/a-cica-365-blemish-calming-serum/for/dry-sensitive-skin): High
- [Oily acne-prone skin](https://lovi.care/skincare/sa/p/aestura/a-cica-365-blemish-calming-serum/for/oily-acne-prone-skin): High

## Key ingredients

Centella Asiatica, Niacinamide, Madecassoside, Beta-Glucan, Squalene

## What the research says

- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Cosmetic formulations containing 5% Centella asiatica extract showed the best efficacy in improving skin moisture and decreasing transepidermal water loss, while also exhibiting antiinflammatory properties in 25 volunteers compared to baseline measurements. ([Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/))
- Co-delivery of paeonol and madecassoside via nanoemulsions improved transdermal delivery, promoted barrier repair proteins, inhibited inflammatory cytokine secretion in cellular and 3D models, and reduced transepidermal water loss and acne in human facial skin compared to free components. ([Molecules, 2023](https://pubmed.ncbi.nlm.nih.gov/37446936/))
- Topical application of 0.05% w/w ECa 233 gel reduced erythema index by 0.03 U and improved early crusting and general wound appearance compared to placebo in thirty individuals undergoing facial laser resurfacing. ([Journal of Alternative and Complementary Medicine, 2020](https://pubmed.ncbi.nlm.nih.gov/32310680/))
- Moisturizer containing 5% panthenol, madecassoside, and copper-zinc-manganese decreased adverse reactions and downtime after ablative fractional carbon dioxide laser resurfacing with comparable efficacy to 0.02% triamcinolone acetonide cream in 20 subjects. ([Journal of Cosmetic Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30945430/))
- Topical treatment with 5% vitamin C and 0.1% madecassoside significantly improved clinical scores for wrinkles, suppleness, firmness, roughness, and skin hydration, along with functional and structural remodeling of the elastic fiber network in 20 female volunteers with photoaged skin after 6 months compared to baseline. ([Experimental Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/18503551/))
- Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33103316/))
- Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women. ([The Journal of Investigative Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/17882270/))
- Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging. ([Dermatologic Surgery, 2005](https://pubmed.ncbi.nlm.nih.gov/16029679/))
- Skin care regimens containing beta-glucan improved hemoglobin index, skin hydration, and transepidermal water loss compared to vehicle control in 20 patients undergoing fractional laser therapy. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33128496/))
- Treatment with topical formulations containing beta-glucan combined with nanofractional radiofrequency plus magnetic nanofractional radiofrequency showed the best efficacy and was tolerable and effective in Chinese women with abdominal stretch marks compared to control groups. ([Dermatology and Therapy, 2023](https://pubmed.ncbi.nlm.nih.gov/37171578/))
- Topical beta-glucan mildly improved striae gravidarum, 1565-nm non-ablative fractional laser showed better results than topical beta-glucan, and the combined strategy further improved striae gravidarum atrophy compared to single treatment. ([The Journal of Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/35570397/))
- A single use of an alpha-tocopherol-enriched rinse-off product strongly increases alpha-tocopherol levels in skin barrier lipids maintained for at least 24 hours and significantly inhibits squalene photooxidation in human volunteers compared to a control product. ([Skin Pharmacology and Physiology, 2005](https://pubmed.ncbi.nlm.nih.gov/15608499/))
- The investigated actives incorporated into alkyl polyglucoside emulsifier-stabilized creams showed no skin irritation and provided increased skin hydration and reduced transepidermal water loss in 76 healthy volunteers. ([Vojnosanitetski Pregled, 2016](https://pubmed.ncbi.nlm.nih.gov/29328637/))
- Topical treatment with a mixed RetinSphere - vitamin E formulation significantly decreased lipid peroxidation levels and oxidized squalene percentage, reduced interleukin-1α concentration in lesional areas, and led to clinical improvement in 18 patients with mild comedonal acne. ([Journal of the European Academy of Dermatology and Venereology, 2014](https://pubmed.ncbi.nlm.nih.gov/24628899/))

## What reviewers say

Based on a very large amount of data, this serum is highly praised by users with sensitive and acne-prone skin for its ability to rapidly soothe redness and repair the skin barrier without causing irritation. The lightweight, non-sticky formula is effective for calming inflammation and improving texture. However, many users find the small bottle size and high price point to be significant drawbacks.

- Disliked: Expensive for size (mostly mentioned)
- Liked: Calms redness fast (often mentioned)
- Liked: Gentle, non-irritating (often mentioned)
- Liked: Lightweight, non-sticky (often mentioned)
- Liked: Hydrating for oily (sometimes noted)
- Liked: Improves texture (sometimes noted)
- Disliked: Not enough for dry (sometimes noted)
- Disliked: Heavy for summer (rarely noted)
- Disliked: Slightly tacky (rarely noted)

## How to apply

- Apply this serum PM, starting 3×/week and working up to daily use as your skin adjusts.
- Place the serum after cleansing and toner, but right before your moisturizer.
- Gently press 2-3 drops of the serum into your skin and let it absorb for a minute.
- Apply the serum on slightly damp skin to help lock in extra moisture.
- Avoid the eye area and do a patch test before your first use.
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### How well does Aestura A-Cica 365 Blemish Calming Serum work for dry skin?

This serum works moderately well for dry skin, offering helpful hydration and soothing irritated areas without causing irritation. To truly thrive, dry skin needs products featuring richer hydrating ingredients, ceramides, and barrier-supporting components.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Which ingredients make this serum a good fit for dry skin?

Glycerin, squalane, madecassoside, and beta-glucan help make this serum a good fit for dry skin by providing moderate hydration to alleviate flakiness and soothing irritation. A treatment of this type needs richer hydrating ingredients, ceramides, and barrier-supporting nutrients to properly care for dry skin.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### What does Centella Asiatica do for dry skin?

Centella asiatica helps dry skin by boosting moisture levels and keeping water locked in to make the skin feel softer and smoother. It also calms redness and supports the natural barrier to prevent everyday irritation.
Sources: [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/), [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### What does Niacinamide do for dry skin?

Niacinamide helps dry skin by strengthening the skin barrier, increasing hydration, and reducing water loss. It supports ceramide production and helps keep the surface smooth and calm. This ingredient tends to be very well tolerated and is unlikely to irritate dry skin.
Sources: [Journal of Cosmetic Dermatology, 2004](https://pubmed.ncbi.nlm.nih.gov/17147561/), [Journal of Cosmetic Dermatology, 2026](https://pubmed.ncbi.nlm.nih.gov/42108609/)

### Where does this serum go in a skincare routine for dry skin?

This treatment goes in the evening routine after cleansing and before moisturizing, which keeps application simple and safe around sun exposure. Dry skin of this type needs richer moisturizers and heavier smoothing ingredients to fully lock in hydration and stop flakiness.

### Can I use this serum with retinol, and in what order?

You can use this serum with retinol by applying the serum first to help calm irritation before your retinol product. This product is generally safe for your dry skin and is unlikely to cause irritation when combined thoughtfully, though dry skin often needs richer oils and heavier barrier-repair creams to fully prevent flakiness.

### How often should I use this serum?

You can use this serum in your evening routine, and a product of this type for dry skin needs richer moisturizing ingredients like ceramides and heavier oils to lock in hydration and deeply soften dry patches.

### Can this serum clog pores, cause breakouts or purging for dry skin?

This serum is unlikely to clog pores or cause breakouts for dry skin, as its gentle formula focuses on calming irritation and providing moderate moisture without harsh ingredients. Dry skin typically needs richer moisturizers packed with heavier hydrating oils and barrier-repairing butters to fully lock in moisture and prevent flakiness.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Is this serum fragrance-free and alcohol-free?

It has no fragrance and contains drying alcohol (alcohol denat).

## Alternatives for dry skin

- [Beauty of Joseon Propolis + Niacinamide Glow Serum](https://lovi.care/skincare/sa/p/beauty-of-joseon/propolis-niacinamide-glow-serum/for/dry-skin) — Superior fit — SAR 226.83 at Amazon
- [Paula's Choice RESIST Super Antioxidant Concentrate Serum](https://lovi.care/skincare/sa/p/paula-s-choice/resist-super-antioxidant-concentrate-serum/for/dry-skin) — Superior fit — SAR 461.00 at Amazon
- [ma:nyo Bifida Biome Complex Ampoule](https://lovi.care/skincare/sa/p/ma-nyo/bifida-biome-complex-ampoule/for/dry-skin) — Superior fit — SAR 145.51 at Amazon

## Pairs well with

- Cleanser: [La Roche-Posay Hydrating Gentle Cleanser](https://lovi.care/skincare/sa/p/la-roche-posay/toleriane-hydrating-gentle-cleanser/for/dry-skin) — Superior fit — SAR 297.00 at Amazon
- Moisturizer: [SKIN1004 Madagascar Centella Probio-Cica Enrich Cream](https://lovi.care/skincare/sa/p/skin1004/madagascar-centella-probio-cica-enrich-cream/for/dry-skin) — Superior fit — SAR 48.00 at Amazon
- SPF: [d'Alba Piedmont Waterfull Mild Sunscreen](https://lovi.care/skincare/sa/p/d-alba/piedmont-waterfull-mild-sunscreen/for/dry-skin) — Superior fit — SAR 75.00 at Amazon

## Where to buy

No store in Saudi Arabia has a checked price for this product, so the page shows none.

## Ingredients

Water, Glycerin, Butylene Glycol, Dipropylene Glycol, Betaine, Niacinamide, 1,2-Hexanediol, Alcohol Denat, Squalene, Diethoxyethyl Succinate, Polyglyceryl-10 Stearate, Sucrose Stearate, Polymethyl Methacrylate, Polyglyceryl-10 Laurate, Phytosterols, Caprylyl Methicone, Carbomer, Hydrogenated Lecithin, Hydrogenated Phosphatidylcholine, Tromethamine, Ethylhexylglycerin, Xanthan Gum, Propanediol, Cellulose Gum, Disodium Edta, Madecassoside, Beta-Glucan, Tocopherol
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/aestura/a-cica-365-blemish-calming-serum/for/dry-skin
- United Kingdom: https://lovi.care/skincare/uk/p/aestura/a-cica-365-blemish-calming-serum/for/dry-skin
- Ireland: https://lovi.care/skincare/ie/p/aestura/a-cica-365-blemish-calming-serum/for/dry-skin
- Germany: https://lovi.care/skincare/de/p/aestura/a-cica-365-blemish-calming-serum/for/dry-skin
- France: https://lovi.care/skincare/fr/p/aestura/a-cica-365-blemish-calming-serum/for/dry-skin
- Italy: https://lovi.care/skincare/it/p/aestura/a-cica-365-blemish-calming-serum/for/dry-skin
- Netherlands: https://lovi.care/skincare/nl/p/aestura/a-cica-365-blemish-calming-serum/for/dry-skin
- Spain: https://lovi.care/skincare/es/p/aestura/a-cica-365-blemish-calming-serum/for/dry-skin
- Canada: https://lovi.care/skincare/ca/p/aestura/a-cica-365-blemish-calming-serum/for/dry-skin
- Australia: https://lovi.care/skincare/au/p/aestura/a-cica-365-blemish-calming-serum/for/dry-skin
- Singapore: https://lovi.care/skincare/sg/p/aestura/a-cica-365-blemish-calming-serum/for/dry-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/aestura/a-cica-365-blemish-calming-serum/for/dry-skin (this page)
- United Arab Emirates: https://lovi.care/skincare/ae/p/aestura/a-cica-365-blemish-calming-serum/for/dry-skin