# A+ 345 Relief Cream for sensitive skin

**Lovi Fit: Average fit for sensitive skin.**
Normal Skin Fit: High · Effectiveness: Average · Safety: High.

Page: https://lovi.care/skincare/sa/p/a/345-relief-cream/for/sensitive-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Saudi Arabia.

Brand: [A+](https://lovi.care/skincare/sa/brands/a)
Category: [Moisturizers and moisturizing serums](https://lovi.care/skincare/sa/best/moisturizers)

This fit is calculated for the concerns frequently associated with sensitive skin: redness, stinging, and reactions to new products. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for sensitive skin; other moisturizers fit it better.

## Why this fit

- This product offers moderate benefits for your normal skin, with glycerin and hyaluronic acid providing excellent hydration and plumping effects that are well-suited to your skin type.
- Ingredients like panthenol and centella asiatica leaf extract offer soothing properties that can help with your redness and irritation, though they are not specifically targeted for significant improvement.
- The formula is safe for your sensitive skin, containing no harsh ingredients and including soothing components like niacinamide and panthenol.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/sa/p/a/345-relief-cream/for/oily-skin): Low
- [Dry skin](https://lovi.care/skincare/sa/p/a/345-relief-cream/for/dry-skin): Average
- [Combination skin](https://lovi.care/skincare/sa/p/a/345-relief-cream/for/combination-skin): Low
- [Sensitive skin](https://lovi.care/skincare/sa/p/a/345-relief-cream/for/sensitive-skin): Average (this page)
- [Acne-prone skin](https://lovi.care/skincare/sa/p/a/345-relief-cream/for/acne-prone-skin): Average
- [Skin with dark spots](https://lovi.care/skincare/sa/p/a/345-relief-cream/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/sa/p/a/345-relief-cream/for/mature-skin): Average
- [Dry sensitive skin](https://lovi.care/skincare/sa/p/a/345-relief-cream/for/dry-sensitive-skin): Average
- [Oily acne-prone skin](https://lovi.care/skincare/sa/p/a/345-relief-cream/for/oily-acne-prone-skin): Average

## Key ingredients

Niacinamide, Hyaluronic Acid, Coptis Japonica Root Extract

## What the research says

- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Topical dexpanthenol acts as a moisturizer, improves stratum corneum hydration, accelerates wound healing and epidermal regeneration, reduces erythema, and improves symptoms of skin irritation compared to vehicle or no pretreatment. ([American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/))
- A panthenol-enriched mask significantly decreased erythema and hyperpigmentation, increased sebum and stratum corneum moisture, and reduced transepidermal water loss compared to a saline dressing in 60 subjects undergoing facial laser treatment. ([Journal of Cosmetic Dermatology, 2025](https://pubmed.ncbi.nlm.nih.gov/40613435/))
- Co-delivery of paeonol and madecassoside via nanoemulsions improved transdermal delivery, promoted barrier repair proteins, inhibited inflammatory cytokine secretion in cellular and 3D models, and reduced transepidermal water loss and acne in human facial skin compared to free components. ([Molecules, 2023](https://pubmed.ncbi.nlm.nih.gov/37446936/))
- A new topical panthenol-containing emollient significantly improved transepidermal water loss reduction, stratum corneum hydration, and intercellular lipid lamellae length compared with control in healthy subjects without negatively impacting bacterial viability. ([The Journal of Dermatological Treatment, 2017](https://pubmed.ncbi.nlm.nih.gov/27425824/))
- Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33103316/))
- Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women. ([The Journal of Investigative Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/17882270/))
- Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging. ([Dermatologic Surgery, 2005](https://pubmed.ncbi.nlm.nih.gov/16029679/))
- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))
- Topical steroid withdrawal is driven by excess mitochondrial NAD+ metabolism that can be successfully targeted using complex I-inhibiting interventions such as metformin and berberine. ([The Journal of Investigative Dermatology, 2025](https://pubmed.ncbi.nlm.nih.gov/40088241/))
- Topical steroid withdrawal presents as a distinct dermatopathology characterized by burning, flushing, thermodysregulation, and elevated mitochondrial NAD+ oxidation, which can be improved by targeting complex I with metformin or berberine. ([MedRxiv, 2024](https://pubmed.ncbi.nlm.nih.gov/38712043/))
- Hydroxypropyl methylcellulose hydrogel formulations of berberine chloride-loaded escinosomes increased skin residence time and transdermal permeability while maintaining high safety and biocompatibility without skin irritation. ([International Journal of Biological Macromolecules, 2020](https://pubmed.ncbi.nlm.nih.gov/32682035/))

## Why other moisturizers fit sensitive skin better

- Soaps containing betaine caused the least skin irritation compared to other tested soaps in twenty-eight healthy subjects, though irritation did not decrease with increasing concentrations of betaine. ([Skin Research and Technology, 2003](https://pubmed.ncbi.nlm.nih.gov/12535284/))

## What reviewers say

Based on a very large amount of data, this lightweight, gel-like cream is widely celebrated by users with oily, combination, and sensitive skin for its ability to soothe redness and fade post-acne marks without clogging pores. However, those with dry skin often find it insufficiently moisturizing, and a subset of users report breakouts or fungal acne triggers despite its soothing claims.

- Liked: Lightweight & fast-absorbing (mostly mentioned)
- Liked: Ideal for oily/combo skin (often mentioned)
- Liked: Soothing & calming (often mentioned)
- Liked: Fades acne marks (sometimes noted)
- Disliked: Not moisturizing enough (sometimes noted)
- Disliked: Caused breakouts (rarely noted)
- Disliked: Fungal acne trigger (rarely noted)
- Disliked: Texture/pilling issues (rarely noted)

## How to apply

- Use this soothing AM and PM routine every day to keep your normal skin calm. Always remember to apply SPF in the morning after your moisturizer.
- Apply your moisturizer after your toner in the morning, and after your serum in the evening. This step locks in hydration and protects your skin.
- Gently press a small amount of the moisturizer evenly across your face. Avoid rubbing to keep your sensitive skin happy and calm.
- You can apply this gentle formula on dry or slightly damp skin for the best comfort. It works wonderfully on clean skin to soothe redness and irritation.
- Do a patch test before your very first use to check your skin's reaction. Avoid getting the product directly into your eyes .
- Video: https://storage.pora.ai/2f72f5d69f07beeafc30237f829efbff.mp4

## Questions and answers

### How well does A+ 345 Relief Cream work for sensitive skin?

A+ 345 Relief Cream works reasonably well for sensitive skin, offering safe hydration and mild soothing benefits for your redness and irritation. To fit this skin better, a moisturizing treatment needs highly effective soothing ingredients like fermented centella asiatica and cica ceramide that strongly target redness and strengthen the skin barrier without overwhelming it.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/), [American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/)

### Which ingredients make this cream a good fit for sensitive skin?

This cream works well for sensitive skin because it includes niacinamide, panthenol, hyaluronic acid, and centella asiatica leaf extract, which help keep skin calm, hydrated, and smooth. This type of product needs soothing ingredients like fermented centella asiatica, cica ceramide, and nourishing oils to strengthen the skin barrier and deliver hydration without causing irritation.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/), [American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/)

### What does Niacinamide do for sensitive skin?

Niacinamide helps calm sensitive skin by strengthening the skin barrier and reducing redness and irritation. It is very well tolerated and may improve overall comfort and resilience with regular use.
Sources: [Cutis, 2005](https://pubmed.ncbi.nlm.nih.gov/16209160/), [Journal of Cosmetic Dermatology, 2004](https://pubmed.ncbi.nlm.nih.gov/17147561/)

### What does Hyaluronic Acid do for sensitive skin?

Hyaluronic acid helps calm and hydrate sensitive skin while supporting the skin barrier to keep it soft and comfortable. Clinical studies show it improves surface moisture and reduces dryness, roughness, and redness without irritation.
Sources: [Journal of Drugs in Dermatology, 2025](https://pubmed.ncbi.nlm.nih.gov/41037531/), [Journal of Cosmetic Dermatology, 2018](https://pubmed.ncbi.nlm.nih.gov/29356277/)

### Where does it go in a skincare routine for sensitive skin?

Apply this treatment in the evening after your soothing toner and before your moisturizer. To best care for sensitive skin, products of this type also need extra soothing and hydrating ingredients like ceramides and centella asiatica leaf extract to strengthen the skin barrier and calm redness.

### Can I use this cream with retinol, and in what order?

You can use this cream alongside retinol by applying the cream after your retinol to help buffer and protect dry skin against irritation. A product for this skin needs gentle barrier-restoring ingredients like ceramides and soothing extracts to keep your face calm and smooth.
Sources: [Cutis, 2006](https://pubmed.ncbi.nlm.nih.gov/17121065/), [American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/)

### How often should I use it?

You can use this moisturizing treatment in your evening routine, applying it after your toner and before your moisturizer. Daily application helps keep skin hydrated and calm.
Sources: [Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/32141711/), [Health Science Reports, 2021](https://pubmed.ncbi.nlm.nih.gov/34141902/)

### Can this cream clog pores, cause breakouts or purging for sensitive skin?

This cream is unlikely to clog pores or cause breakouts for sensitive skin, as it has a very low risk of causing breakouts based on user feedback. To keep sensitive skin clear and comfortable, a moisturizer of this type needs soothing ingredients like centella asiatica and panthenol, alongside reliable hydrators like glycerin and hyaluronic acid.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/), [American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/)

### Can I use it around the eyes or on my body?

You can use this moisturizing treatment around the eyes and on the body because its formula has a very good safety profile for sensitive skin. However, since skin around the eyes is exceptionally thin and body skin can be thicker, a product of this type needs richer or more targeted hydrating ingredients and barrier-supporting components to provide an optimal fit for those areas.
Sources: [Surgical and Radiologic Anatomy, 2002](https://pubmed.ncbi.nlm.nih.gov/12375070/), [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Is this cream fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for sensitive skin

- [SKIN1004 Madagascar Centella Probio-Cica Enrich Cream](https://lovi.care/skincare/sa/p/skin1004/madagascar-centella-probio-cica-enrich-cream/for/sensitive-skin) — Superior fit — SAR 48.00 at Amazon
- [COSRX Advanced Snail 96 Mucin Power Essence](https://lovi.care/skincare/sa/p/cosrx/advanced-snail-96-mucin-power-essence/for/sensitive-skin) — Superior fit — SAR 14.95 at Amazon
- [COSRX Advanced Snail 92 All in One Cream](https://lovi.care/skincare/sa/p/cosrx/advanced-snail-92-all-in-one-cream/for/sensitive-skin) — Superior fit — SAR 79.00 at Amazon

## Pairs well with

- Cleanser: [Fresh Soy Face Cleanser](https://lovi.care/skincare/sa/p/fresh/soy-face-cleanser/for/sensitive-skin) — Superior fit — SAR 191.00 at Amazon
- Soothing Toner: [Clarins Toning Lotion with Camomile](https://lovi.care/skincare/sa/p/clarins/soothing-toning-lotion/for/sensitive-skin) — Superior fit — SAR 141.00 at Amazon
- Moisturizer with Sun Protection: [Bioderma Bioderma Photoderm Mineral SPF 50+](https://lovi.care/skincare/sa/p/bioderma/photoderm-mineral-fluide-spf50/for/sensitive-skin) — Superior fit — SAR 132.22 at Amazon

## Where to buy

No store in Saudi Arabia has a checked price for this product, so the page shows none.

## Ingredients

Water, Propanediol, Glycerin, Cyclohexasiloxane, 1,2-Hexanediol, Niacinamide, Caprylic Capric Triglyceride, Polyglycerin-3, Panthenol, Polyglyceryl-10 Stearate, Hydrogenated Polydecene, Hydrogenated Poly C6-14 Olefin, Dicaprylyl Carbonate, Ammonium Acryloyldimethyltaurate Vp Copolymer, C14-22 Alcohols, Polymethylsilsesquioxane, C12-20 Alkyl Glucoside, Butylene Glycol, Acrylates C10-30 Alkyl Acrylate Crosspolymer, Ethylhexylglycerin, Polyquaternium-51, Tromethamine, Hyaluronic Acid, Coptis Japonica Root Extract, Houttuynia Cordata Extract, Oenothera Biennis Flower Extract, Beta-Glucan, Resveratrol, Gardenia Florida Fruit Extract, Lavandula Angustifolia Flower Extract Lavender Flower Extract, Opuntia Ficus-Indica Stem Extract, Hydrolyzed Hyaluronic Acid, Centella Asiatica Leaf Extract, Phenoxyethanol, Hibiscus Sabdariffa Flower Extract, Tocopherol, Corallina Officinalis Extract, Ceramide Np
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/a/345-relief-cream/for/sensitive-skin
- United Kingdom: https://lovi.care/skincare/uk/p/a/345-relief-cream/for/sensitive-skin
- Ireland: https://lovi.care/skincare/ie/p/a/345-relief-cream/for/sensitive-skin
- Germany: https://lovi.care/skincare/de/p/a/345-relief-cream/for/sensitive-skin
- France: https://lovi.care/skincare/fr/p/a/345-relief-cream/for/sensitive-skin
- Italy: https://lovi.care/skincare/it/p/a/345-relief-cream/for/sensitive-skin
- Netherlands: https://lovi.care/skincare/nl/p/a/345-relief-cream/for/sensitive-skin
- Spain: https://lovi.care/skincare/es/p/a/345-relief-cream/for/sensitive-skin
- Canada: https://lovi.care/skincare/ca/p/a/345-relief-cream/for/sensitive-skin
- Australia: https://lovi.care/skincare/au/p/a/345-relief-cream/for/sensitive-skin
- Singapore: https://lovi.care/skincare/sg/p/a/345-relief-cream/for/sensitive-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/a/345-relief-cream/for/sensitive-skin (this page)
- United Arab Emirates: https://lovi.care/skincare/ae/p/a/345-relief-cream/for/sensitive-skin