# Lipohydroxy acid

Page: https://lovi.care/skincare/sa/ingredients/lipohydroxy-acid

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Saudi Arabia.

Lipohydroxy acid gently smooths skin texture, softens fine lines, reduces dark spots, balances oil, and clears blemishes while encouraging gentle renewal. It suits dry skin and oily skin particularly well, and is most commonly found in exfoliators and toners. When applying it, simply keep it apart from [niacinamide](https://lovi.care/skincare/sa/ingredients/niacinamide) to support a balanced daily routine.

[Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33617668/) [Journal of Cosmetic Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/19146601/) [Cutis, 2012](https://pubmed.ncbi.nlm.nih.gov/22838094/)

This page shows lipohydroxy acid products with a Lovi page. For every product, and a routine built for your skin, use the Lovi app.

### Popular lipohydroxy acid products

- [La Roche-Posay Effaclar Medicated Gel Cleanser](https://lovi.care/skincare/sa/p/la-roche-posay/effaclar-medicated-gel-cleanser/for/acne-prone-skin) — High fit
- [SkinCeuticals LHA Cleanser Gel](https://lovi.care/skincare/sa/p/skinceuticals/lha-cleanser-gel/for/oily-acne-prone-skin) — High fit
- [SkinCeuticals Blemish + Age Defense](https://lovi.care/skincare/sa/p/skinceuticals/blemish-age-defense/for/oily-skin) — Superior fit — [SAR 458.33 at Amazon](https://www.amazon.sa/dp/B07HCGKJ76?tag=lovisa02-21&linkCode=osi&th=1&psc=1)
- [L'Oreal Paris Age Perfect Cell Renewal Midnight Cream](https://lovi.care/skincare/sa/p/l-oreal-paris/age-perfect-cell-renewal-midnight-cream/for/dry-sensitive-skin) — High fit
- [La Roche-Posay Effaclar Mat](https://lovi.care/skincare/sa/p/la-roche-posay/effaclar-mat/for/combination-skin) — Average fit — [SAR 44.89 at Amazon](https://www.amazon.sa/dp/B00B4RJP72?tag=lovisa02-21&linkCode=osi&th=1&psc=1)
- [La Roche-Posay Effaclar Clarifying Solution](https://lovi.care/skincare/sa/p/la-roche-posay/effaclar-clarifying-solution/for/oily-acne-prone-skin) — High fit
- [La Roche-Posay Effaclar Ultra Concentrated Serum](https://lovi.care/skincare/sa/p/la-roche-posay/effaclar-ultra-concentrated-serum/for/oily-acne-prone-skin) — High fit — [SAR 142.00 at Amazon](https://www.amazon.sa/dp/B08H81SZKH?tag=lovisa02-21&linkCode=osi&th=1&psc=1)
- [MEDIHEAL Phyto-Enzyme Peeling Pad](https://lovi.care/skincare/sa/p/mediheal/phyto-enzyme-peeling-pad/for/mature-skin) — High fit — [SAR 118.00 at Amazon](https://www.amazon.sa/dp/B0C6F2VL93?tag=lovisa02-21&linkCode=osi&th=1&psc=1)

### Lipohydroxy acid exfoliators

- [La Roche-Posay Effaclar Clarifying Solution](https://lovi.care/skincare/sa/p/la-roche-posay/effaclar-clarifying-solution/for/oily-acne-prone-skin) — High fit
- [La Roche-Posay Effaclar Ultra Concentrated Serum](https://lovi.care/skincare/sa/p/la-roche-posay/effaclar-ultra-concentrated-serum/for/oily-acne-prone-skin) — High fit — [SAR 142.00 at Amazon](https://www.amazon.sa/dp/B08H81SZKH?tag=lovisa02-21&linkCode=osi&th=1&psc=1)
- [MEDIHEAL Phyto-Enzyme Peeling Pad](https://lovi.care/skincare/sa/p/mediheal/phyto-enzyme-peeling-pad/for/mature-skin) — High fit — [SAR 118.00 at Amazon](https://www.amazon.sa/dp/B0C6F2VL93?tag=lovisa02-21&linkCode=osi&th=1&psc=1)
- [StriVectin Daily Reveal Exfoliating Pads](https://lovi.care/skincare/sa/p/strivectin/daily-reveal-exfoliating-pads/for/oily-skin) — Average fit — [SAR 241.56 at Amazon](https://www.amazon.sa/dp/B089TPYFX3?tag=lovisa02-21&linkCode=osi&th=1&psc=1)
- [Anua Heartleaf LHA Moisture Peeling Gel](https://lovi.care/skincare/sa/p/anua/heartleaf-lha-moisture-peeling-gel/for/dark-spots) — High fit — [SAR 24.35 at Amazon](https://www.amazon.sa/dp/B0BVVJYVBK?tag=lovisa02-21&linkCode=osi&th=1&psc=1)
- [La Roche-Posay Effaclar Micro-Peeling Purifying Gel](https://lovi.care/skincare/sa/p/la-roche-posay/effaclar-micro-peeling-purifying-gel/for/oily-acne-prone-skin) — High fit

## What reviewers say about popular lipohydroxy acid products

The highlight reviewers mention most for each popular lipohydroxy acid product on Lovi.

- La Roche-Posay Effaclar Medicated Gel Cleanser Controls oil ★4.6 · 2.3k+ reviews Deep clean Gentle formula “removes excess oil” [What people say about Effaclar Medicated Gel Cleanser](https://lovi.care/skincare/sa/p/la-roche-posay/effaclar-medicated-gel-cleanser/for/acne-prone-skin)
- SkinCeuticals LHA Cleanser Gel Deeply exfoliates ★4.6 · 800+ reviews Controls oil Refines texture “decongests clogged pores” [What people say about LHA Cleanser Gel](https://lovi.care/skincare/sa/p/skinceuticals/lha-cleanser-gel/for/oily-acne-prone-skin)
- SkinCeuticals Blemish + Age Defense Clears stubborn acne ★4.6 · 1.9k+ reviews Improves skin texture Reduces excess oil “cystic acne shrinking” [What people say about Blemish + Age Defense](https://lovi.care/skincare/sa/p/skinceuticals/blemish-age-defense/for/oily-skin)
- L'Oreal Paris Age Perfect Cell Renewal Midnight Cream Deep hydration ★4.6 · 6.6k+ reviews Luxurious texture Visible radiance “wake up with soft skin” [What people say about Age Perfect Cell Renewal Midnight Cream](https://lovi.care/skincare/sa/p/l-oreal-paris/age-perfect-cell-renewal-midnight-cream/for/dry-sensitive-skin)
- La Roche-Posay Effaclar Mat Effective Oil Control ★4.4 · 1.4k+ reviews Excellent Makeup Base Lightweight Texture “sucked up the shine” [What people say about Effaclar Mat](https://lovi.care/skincare/sa/p/la-roche-posay/effaclar-mat/for/combination-skin)
- La Roche-Posay Effaclar Clarifying Solution Minimizes pores ★4.5 · 2.2k+ reviews Gentle and non-drying Smoothes texture “effective at unclogging pores” [What people say about Effaclar Clarifying Solution](https://lovi.care/skincare/sa/p/la-roche-posay/effaclar-clarifying-solution/for/oily-acne-prone-skin)

### Lipohydroxy acid toners

- [Kiehl's Daily Refining Milk-Peel Toner](https://lovi.care/skincare/sa/p/kiehl-s/daily-refining-milk-peel-toner/for/mature-skin) — High fit
- [Troubless Clear Toner Pad](https://lovi.care/skincare/sa/p/troubless/clear-toner-pad/for/oily-acne-prone-skin) — Superior fit — [SAR 49.00 at Amazon](https://www.amazon.sa/dp/B0BNJNCR82?tag=lovisa02-21&linkCode=osi&th=1&psc=1)
- [ma:nyo Galactomy Clearskin Toner](https://lovi.care/skincare/sa/p/ma-nyo/galactomy-clearskin-toner/for/oily-acne-prone-skin) — Superior fit — [SAR 140.87 at Amazon](https://www.amazon.sa/dp/B08ZMZTBS4?tag=lovisa02-21&linkCode=osi&th=1&psc=1)
- [SkinCeuticals LHA Toner](https://lovi.care/skincare/sa/p/skinceuticals/lha-toner/for/oily-skin) — Superior fit
- [Kiehl's Iris Extract Activating Treatment Essence](https://lovi.care/skincare/sa/p/kiehl-s/iris-extract-activating-treatment-essence/for/combination-skin) — High fit — [SAR 490.00 at Amazon](https://www.amazon.sa/dp/B00UW7PVLO?tag=lovisa02-21&linkCode=osi&th=1&psc=1)

### Other lipohydroxy acid products

- [La Roche-Posay Effaclar Medicated Gel Cleanser](https://lovi.care/skincare/sa/p/la-roche-posay/effaclar-medicated-gel-cleanser/for/acne-prone-skin) — High fit
- [SkinCeuticals LHA Cleanser Gel](https://lovi.care/skincare/sa/p/skinceuticals/lha-cleanser-gel/for/oily-acne-prone-skin) — High fit
- [Garnier Express Aclara](https://lovi.care/skincare/sa/p/garnier/express-aclara/for/oily-acne-prone-skin) — Average fit
- [Minimalist Salicylic Acid + LHA 2% Face Cleanser](https://lovi.care/skincare/sa/p/minimalist/salicylic-acid-lha-2-face-cleanser/for/acne-prone-skin) — Superior fit — [SAR 127.09 at Amazon](https://www.amazon.sa/dp/B0D3WX7G3H?tag=lovisa02-21&linkCode=osi&th=1&psc=1)
- [L'Oreal Paris Age Perfect Cell Renewal Midnight Cream](https://lovi.care/skincare/sa/p/l-oreal-paris/age-perfect-cell-renewal-midnight-cream/for/dry-sensitive-skin) — High fit
- [La Roche-Posay Effaclar Mat](https://lovi.care/skincare/sa/p/la-roche-posay/effaclar-mat/for/combination-skin) — Average fit — [SAR 44.89 at Amazon](https://www.amazon.sa/dp/B00B4RJP72?tag=lovisa02-21&linkCode=osi&th=1&psc=1)
- [SkinCeuticals Blemish + Age Defense](https://lovi.care/skincare/sa/p/skinceuticals/blemish-age-defense/for/oily-skin) — Superior fit — [SAR 458.33 at Amazon](https://www.amazon.sa/dp/B07HCGKJ76?tag=lovisa02-21&linkCode=osi&th=1&psc=1)
- [La Roche-Posay Redermic R](https://lovi.care/skincare/sa/p/la-roche-posay/redermic-r/for/mature-skin) — High fit
- [Kiehl's Vital Skin-Strengthening Super Serum](https://lovi.care/skincare/sa/p/kiehl-s/vital-skin-strengthening-super-serum/for/mature-skin) — Average fit — [SAR 337.83 at Amazon](https://www.amazon.sa/dp/B092RBKPTC?tag=lovisa02-21&linkCode=osi&th=1&psc=1)

### Lipohydroxy acid for dry skin

- [L'Oreal Paris Age Perfect Cell Renewal Midnight Cream](https://lovi.care/skincare/sa/p/l-oreal-paris/age-perfect-cell-renewal-midnight-cream/for/dry-skin) — High fit
- [Kiehl's Daily Refining Milk-Peel Toner](https://lovi.care/skincare/sa/p/kiehl-s/daily-refining-milk-peel-toner/for/dry-skin) — High fit
- [MEDIHEAL Phyto-Enzyme Peeling Pad](https://lovi.care/skincare/sa/p/mediheal/phyto-enzyme-peeling-pad/for/dry-skin) — Average fit — [SAR 118.00 at Amazon](https://www.amazon.sa/dp/B0C6F2VL93?tag=lovisa02-21&linkCode=osi&th=1&psc=1)
- [Kiehl's Vital Skin-Strengthening Super Serum](https://lovi.care/skincare/sa/p/kiehl-s/vital-skin-strengthening-super-serum/for/dry-skin) — Average fit — [SAR 337.83 at Amazon](https://www.amazon.sa/dp/B092RBKPTC?tag=lovisa02-21&linkCode=osi&th=1&psc=1)
- [Anua Heartleaf LHA Moisture Peeling Gel](https://lovi.care/skincare/sa/p/anua/heartleaf-lha-moisture-peeling-gel/for/dry-skin) — Average fit — [SAR 24.35 at Amazon](https://www.amazon.sa/dp/B0BVVJYVBK?tag=lovisa02-21&linkCode=osi&th=1&psc=1)
- [Troubless Clear Toner Pad](https://lovi.care/skincare/sa/p/troubless/clear-toner-pad/for/dry-skin) — Average fit — [SAR 49.00 at Amazon](https://www.amazon.sa/dp/B0BNJNCR82?tag=lovisa02-21&linkCode=osi&th=1&psc=1)
- [SkinCeuticals Blemish + Age Defense](https://lovi.care/skincare/sa/p/skinceuticals/blemish-age-defense/for/dry-skin) — Average fit — [SAR 458.33 at Amazon](https://www.amazon.sa/dp/B07HCGKJ76?tag=lovisa02-21&linkCode=osi&th=1&psc=1)
- [StriVectin Daily Reveal Exfoliating Pads](https://lovi.care/skincare/sa/p/strivectin/daily-reveal-exfoliating-pads/for/dry-skin) — Average fit — [SAR 241.56 at Amazon](https://www.amazon.sa/dp/B089TPYFX3?tag=lovisa02-21&linkCode=osi&th=1&psc=1)
- [Kiehl's Iris Extract Activating Treatment Essence](https://lovi.care/skincare/sa/p/kiehl-s/iris-extract-activating-treatment-essence/for/dry-skin) — Low fit — [SAR 490.00 at Amazon](https://www.amazon.sa/dp/B00UW7PVLO?tag=lovisa02-21&linkCode=osi&th=1&psc=1)
- [La Roche-Posay Effaclar Medicated Gel Cleanser](https://lovi.care/skincare/sa/p/la-roche-posay/effaclar-medicated-gel-cleanser/for/dry-skin) — Low fit
- [La Roche-Posay Redermic R](https://lovi.care/skincare/sa/p/la-roche-posay/redermic-r/for/dry-skin) — Low fit
- [SkinCeuticals LHA Cleanser Gel](https://lovi.care/skincare/sa/p/skinceuticals/lha-cleanser-gel/for/dry-skin) — Caution fit

### Lipohydroxy acid for oily skin

- [SkinCeuticals Blemish + Age Defense](https://lovi.care/skincare/sa/p/skinceuticals/blemish-age-defense/for/oily-skin) — Superior fit — [SAR 458.33 at Amazon](https://www.amazon.sa/dp/B07HCGKJ76?tag=lovisa02-21&linkCode=osi&th=1&psc=1)
- [SkinCeuticals LHA Toner](https://lovi.care/skincare/sa/p/skinceuticals/lha-toner/for/oily-skin) — Superior fit
- [Minimalist Salicylic Acid + LHA 2% Face Cleanser](https://lovi.care/skincare/sa/p/minimalist/salicylic-acid-lha-2-face-cleanser/for/oily-skin) — High fit — [SAR 127.09 at Amazon](https://www.amazon.sa/dp/B0D3WX7G3H?tag=lovisa02-21&linkCode=osi&th=1&psc=1)
- [ma:nyo Galactomy Clearskin Toner](https://lovi.care/skincare/sa/p/ma-nyo/galactomy-clearskin-toner/for/oily-skin) — High fit — [SAR 140.87 at Amazon](https://www.amazon.sa/dp/B08ZMZTBS4?tag=lovisa02-21&linkCode=osi&th=1&psc=1)
- [Troubless Clear Toner Pad](https://lovi.care/skincare/sa/p/troubless/clear-toner-pad/for/oily-skin) — High fit — [SAR 49.00 at Amazon](https://www.amazon.sa/dp/B0BNJNCR82?tag=lovisa02-21&linkCode=osi&th=1&psc=1)
- [La Roche-Posay Effaclar Clarifying Solution](https://lovi.care/skincare/sa/p/la-roche-posay/effaclar-clarifying-solution/for/oily-skin) — High fit
- [Kiehl's Daily Refining Milk-Peel Toner](https://lovi.care/skincare/sa/p/kiehl-s/daily-refining-milk-peel-toner/for/oily-skin) — High fit
- [SkinCeuticals LHA Cleanser Gel](https://lovi.care/skincare/sa/p/skinceuticals/lha-cleanser-gel/for/oily-skin) — High fit
- [La Roche-Posay Effaclar Ultra Concentrated Serum](https://lovi.care/skincare/sa/p/la-roche-posay/effaclar-ultra-concentrated-serum/for/oily-skin) — High fit — [SAR 142.00 at Amazon](https://www.amazon.sa/dp/B08H81SZKH?tag=lovisa02-21&linkCode=osi&th=1&psc=1)
- [MEDIHEAL Phyto-Enzyme Peeling Pad](https://lovi.care/skincare/sa/p/mediheal/phyto-enzyme-peeling-pad/for/oily-skin) — High fit — [SAR 118.00 at Amazon](https://www.amazon.sa/dp/B0C6F2VL93?tag=lovisa02-21&linkCode=osi&th=1&psc=1)
- [La Roche-Posay Effaclar Medicated Gel Cleanser](https://lovi.care/skincare/sa/p/la-roche-posay/effaclar-medicated-gel-cleanser/for/oily-skin) — High fit
- [La Roche-Posay Redermic R](https://lovi.care/skincare/sa/p/la-roche-posay/redermic-r/for/oily-skin) — Average fit

### Lipohydroxy acid for combination skin

- [Minimalist Salicylic Acid + LHA 2% Face Cleanser](https://lovi.care/skincare/sa/p/minimalist/salicylic-acid-lha-2-face-cleanser/for/combination-skin) — Superior fit — [SAR 127.09 at Amazon](https://www.amazon.sa/dp/B0D3WX7G3H?tag=lovisa02-21&linkCode=osi&th=1&psc=1)
- [Troubless Clear Toner Pad](https://lovi.care/skincare/sa/p/troubless/clear-toner-pad/for/combination-skin) — High fit — [SAR 49.00 at Amazon](https://www.amazon.sa/dp/B0BNJNCR82?tag=lovisa02-21&linkCode=osi&th=1&psc=1)
- [SkinCeuticals Blemish + Age Defense](https://lovi.care/skincare/sa/p/skinceuticals/blemish-age-defense/for/combination-skin) — High fit — [SAR 458.33 at Amazon](https://www.amazon.sa/dp/B07HCGKJ76?tag=lovisa02-21&linkCode=osi&th=1&psc=1)
- [ma:nyo Galactomy Clearskin Toner](https://lovi.care/skincare/sa/p/ma-nyo/galactomy-clearskin-toner/for/combination-skin) — High fit — [SAR 140.87 at Amazon](https://www.amazon.sa/dp/B08ZMZTBS4?tag=lovisa02-21&linkCode=osi&th=1&psc=1)
- [Kiehl's Iris Extract Activating Treatment Essence](https://lovi.care/skincare/sa/p/kiehl-s/iris-extract-activating-treatment-essence/for/combination-skin) — High fit — [SAR 490.00 at Amazon](https://www.amazon.sa/dp/B00UW7PVLO?tag=lovisa02-21&linkCode=osi&th=1&psc=1)
- [La Roche-Posay Effaclar Medicated Gel Cleanser](https://lovi.care/skincare/sa/p/la-roche-posay/effaclar-medicated-gel-cleanser/for/combination-skin) — High fit
- [SkinCeuticals LHA Toner](https://lovi.care/skincare/sa/p/skinceuticals/lha-toner/for/combination-skin) — High fit
- [La Roche-Posay Effaclar Ultra Concentrated Serum](https://lovi.care/skincare/sa/p/la-roche-posay/effaclar-ultra-concentrated-serum/for/combination-skin) — High fit — [SAR 142.00 at Amazon](https://www.amazon.sa/dp/B08H81SZKH?tag=lovisa02-21&linkCode=osi&th=1&psc=1)
- [MEDIHEAL Phyto-Enzyme Peeling Pad](https://lovi.care/skincare/sa/p/mediheal/phyto-enzyme-peeling-pad/for/combination-skin) — High fit — [SAR 118.00 at Amazon](https://www.amazon.sa/dp/B0C6F2VL93?tag=lovisa02-21&linkCode=osi&th=1&psc=1)
- [Kiehl's Daily Refining Milk-Peel Toner](https://lovi.care/skincare/sa/p/kiehl-s/daily-refining-milk-peel-toner/for/combination-skin) — High fit
- [Anua Heartleaf LHA Moisture Peeling Gel](https://lovi.care/skincare/sa/p/anua/heartleaf-lha-moisture-peeling-gel/for/combination-skin) — Average fit — [SAR 24.35 at Amazon](https://www.amazon.sa/dp/B0BVVJYVBK?tag=lovisa02-21&linkCode=osi&th=1&psc=1)
- [La Roche-Posay Redermic R](https://lovi.care/skincare/sa/p/la-roche-posay/redermic-r/for/combination-skin) — Average fit

### Lipohydroxy acid for sensitive skin

- [Kiehl's Daily Refining Milk-Peel Toner](https://lovi.care/skincare/sa/p/kiehl-s/daily-refining-milk-peel-toner/for/sensitive-skin) — High fit
- [Kiehl's Iris Extract Activating Treatment Essence](https://lovi.care/skincare/sa/p/kiehl-s/iris-extract-activating-treatment-essence/for/sensitive-skin) — High fit — [SAR 490.00 at Amazon](https://www.amazon.sa/dp/B00UW7PVLO?tag=lovisa02-21&linkCode=osi&th=1&psc=1)
- [Anua Heartleaf LHA Moisture Peeling Gel](https://lovi.care/skincare/sa/p/anua/heartleaf-lha-moisture-peeling-gel/for/sensitive-skin) — High fit — [SAR 24.35 at Amazon](https://www.amazon.sa/dp/B0BVVJYVBK?tag=lovisa02-21&linkCode=osi&th=1&psc=1)
- [La Roche-Posay Effaclar Ultra Concentrated Serum](https://lovi.care/skincare/sa/p/la-roche-posay/effaclar-ultra-concentrated-serum/for/sensitive-skin) — High fit — [SAR 142.00 at Amazon](https://www.amazon.sa/dp/B08H81SZKH?tag=lovisa02-21&linkCode=osi&th=1&psc=1)
- [Troubless Clear Toner Pad](https://lovi.care/skincare/sa/p/troubless/clear-toner-pad/for/sensitive-skin) — Average fit — [SAR 49.00 at Amazon](https://www.amazon.sa/dp/B0BNJNCR82?tag=lovisa02-21&linkCode=osi&th=1&psc=1)
- [MEDIHEAL Phyto-Enzyme Peeling Pad](https://lovi.care/skincare/sa/p/mediheal/phyto-enzyme-peeling-pad/for/sensitive-skin) — Average fit — [SAR 118.00 at Amazon](https://www.amazon.sa/dp/B0C6F2VL93?tag=lovisa02-21&linkCode=osi&th=1&psc=1)
- [L'Oreal Paris Age Perfect Cell Renewal Midnight Cream](https://lovi.care/skincare/sa/p/l-oreal-paris/age-perfect-cell-renewal-midnight-cream/for/sensitive-skin) — Average fit
- [Kiehl's Vital Skin-Strengthening Super Serum](https://lovi.care/skincare/sa/p/kiehl-s/vital-skin-strengthening-super-serum/for/sensitive-skin) — Average fit — [SAR 337.83 at Amazon](https://www.amazon.sa/dp/B092RBKPTC?tag=lovisa02-21&linkCode=osi&th=1&psc=1)
- [SkinCeuticals Blemish + Age Defense](https://lovi.care/skincare/sa/p/skinceuticals/blemish-age-defense/for/sensitive-skin) — Average fit — [SAR 458.33 at Amazon](https://www.amazon.sa/dp/B07HCGKJ76?tag=lovisa02-21&linkCode=osi&th=1&psc=1)
- [ma:nyo Galactomy Clearskin Toner](https://lovi.care/skincare/sa/p/ma-nyo/galactomy-clearskin-toner/for/sensitive-skin) — Average fit — [SAR 140.87 at Amazon](https://www.amazon.sa/dp/B08ZMZTBS4?tag=lovisa02-21&linkCode=osi&th=1&psc=1)
- [La Roche-Posay Redermic R](https://lovi.care/skincare/sa/p/la-roche-posay/redermic-r/for/sensitive-skin) — Average fit
- [SkinCeuticals LHA Cleanser Gel](https://lovi.care/skincare/sa/p/skinceuticals/lha-cleanser-gel/for/sensitive-skin) — Average fit

## What to combine lipohydroxy acid with

Ingredient Together How to use them

[Niacinamide](https://lovi.care/skincare/sa/ingredients/niacinamide) Keep apart Use them at different times of day, applying the hydroxy acid first and [niacinamide](https://lovi.care/skincare/sa/ingredients/niacinamide) later, because combining them causes irritation. [Lipohydroxy acid and niacinamide](https://lovi.care/skincare/sa/ingredients/niacinamide-and-lipohydroxy-acid)

From the ingredient rules behind the "Works well with" and "Don't mix with" notes on every product in the Lovi app.

## Questions and answers

### What does lipohydroxy acid do for the skin?

Lipohydroxy acid helps reduce acne severity, post-inflammatory dark spots, and oiliness, and may improve the look of fine lines, wrinkles, and skin texture. It also helps smooth and thicken the outer skin layer for a more even appearance.

[Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33617668/) [Journal of Cosmetic Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/19146601/)

### How do you use lipohydroxy acid?

You use lipohydroxy acid daily, or as directed by your product, but you should keep it apart from [niacinamide](https://lovi.care/skincare/sa/ingredients/niacinamide) by using them at different times of day with the hydroxy acid applied first to avoid irritation. It may help reduce acne, fine lines, and hyperpigmentation when used as part of your routine.

[Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33617668/) [Journal of Cosmetic Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/19146601/)

### Should you use lipohydroxy acid in the morning or at night?

You can use lipohydroxy acid in your routine, but you should keep it apart from niacinamide by using them at different times of day and applying the hydroxy acid first. This helps prevent irritation.

### Can you use lipohydroxy acid every day?

Yes, you can use lipohydroxy acid daily, as daily treatment with products containing it helps control oily skin and reduce acne lesions. It is unlikely to cause adverse reactions when used as directed in facial [serums](https://lovi.care/skincare/sa/ingredients/serum) and masks.

[Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33617668/) [Journal of Cosmetic Dermatology, 2023](https://pubmed.ncbi.nlm.nih.gov/36999489/)

### Does lipohydroxy acid cause purging or irritation?

Lipohydroxy acid may cause irritation when combined with niacinamide, so keep them apart by using them at different times of day and applying the hydroxy acid first. Lovi assigns this a fit rating based on compatibility rules.

### Which skin types is lipohydroxy acid best for?

Lipohydroxy acid is well suited for various skin types, with top-rated options including SkinCeuticals Blemish + Age Defense for oily skin and ma:nyo Galactomy Clearskin Toner for acne-prone skin. Lovi rates SkinCeuticals Blemish + Age Defense as a Superior fit for oily skin.

[Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33617668/)

### Can you use lipohydroxy acid with niacinamide?

You should keep lipohydroxy acid and niacinamide apart and use them at different times of day, applying the hydroxy acid first and niacinamide later, because combining them causes irritation.

## Research on lipohydroxy acid

- [Clinical evaluation of the efficacy of a facial serum containing dioic acid, glycolic acid, salicylic acid, LHA, citric acid, and HEPES in treating post-inflammatory hyperchromia and controlling oily skin in patients with acne vulgaris](https://pubmed.ncbi.nlm.nih.gov/33617668/) Lipohydroxy acid · Journal of Cosmetic Dermatology, 2021
- [Clinical tolerance and efficacy of capryloyl salicylic acid peel compared to a glycolic acid peel in subjects with fine lines/wrinkles and hyperpigmented skin](https://pubmed.ncbi.nlm.nih.gov/19146601/) Lipohydroxy acid · Journal of Cosmetic Dermatology, 2008
- [A multicenter, double-blind study to evaluate the efficacy and safety of 2 treatments in participants with mild to moderate acne vulgaris](https://pubmed.ncbi.nlm.nih.gov/22838094/) Lipohydroxy acid · Cutis, 2012
- [Comparison of clindamycin 1% and benzoyl peroxide 5% gel to a novel composition containing salicylic acid, capryloyl salicylic acid, HEPES, glycolic acid, citric acid, and dioic acid in the treatment of acne vulgaris](https://pubmed.ncbi.nlm.nih.gov/23545907/) Lipohydroxy acid · Journal of Drugs in Dermatology, 2013
- [Efficacy and safety of a facial serum and a mask containing salicylic acid and lipohydroxy acid in acne management: A randomized controlled trial](https://pubmed.ncbi.nlm.nih.gov/36999489/) Lipohydroxy acid · Journal of Cosmetic Dermatology, 2023

## Combining lipohydroxy acid

- Keep them apart: [Niacinamide and lipohydroxy acid](https://lovi.care/skincare/sa/ingredients/niacinamide-and-lipohydroxy-acid)

## Brands with lipohydroxy acid

- French skincare: [La Roche-Posay](https://lovi.care/skincare/sa/brands/la-roche-posay)
- Korean skincare: [Anua](https://lovi.care/skincare/sa/brands/anua)
- Korean skincare: [MEDIHEAL](https://lovi.care/skincare/sa/brands/mediheal)
- Indian skincare: [Minimalist](https://lovi.care/skincare/sa/brands/minimalist)
- American skincare: [SkinCeuticals](https://lovi.care/skincare/sa/brands/skinceuticals)
- American skincare: [Kiehl's](https://lovi.care/skincare/sa/brands/kiehl-s)
- Korean skincare: [Troubless](https://lovi.care/skincare/sa/brands/troubless)
- French skincare: [L'Oreal Paris](https://lovi.care/skincare/sa/brands/l-oreal-paris)
- American skincare: [StriVectin](https://lovi.care/skincare/sa/brands/strivectin)
- French skincare: [Garnier](https://lovi.care/skincare/sa/brands/garnier)

## Related ingredients

- [Niacinamide](https://lovi.care/skincare/sa/ingredients/niacinamide)

## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi checks every ingredient with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this ingredient guide: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

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